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Results for MligTC455_53961

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53961 290 6.04 Mlig455_051313

Neo: -

Age: logFC(26M/2M)=-0.591

Region-enriched R2: 2.488/0.02898

TTLL7 Mlig455_051313 {REF} {Length: 3404} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=247.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.8]; YheC/D like ATP-grasp [PF14398.8, score=18.8]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [RH, Score=478, Expect=1e-157]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [RH, Score=474, Expect=2e-153]} {Dmel: FBgn0039501, CG5987, [Score=289, Expect=2e-85]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=184, Expect=5e-49]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [RH, Score=408, Expect=4e-128]} {RNA1509_8901} {RNA1310_4651, RNA1509_8901} {RNA1509_8901, RNA815_1757}

Cumulative graph for MligTC455_53961

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.236 2.947 0.11798 0.70722
RegionR2 2.488 2.947 0.00152 0.02898
RegionR3 0.934 2.947 0.27121 0.81561
RegionR4 0.271 2.947 0.73331 1.00000
RegionR5 0.28 2.947 0.72065 1.00000
RegionR6 1.14 2.947 0.16549 0.72003
RegionR7 0.047 2.947 0.84375 1.00000
RegionR8 1.076 2.947 0.37461 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 6.159 2.947 0.19605 0.93505
RegenerationR2 0.005 2.947 0.99341 1.00000
RegenerationR3 -0.153 2.947 0.77831 0.97458
RegenerationR4 -0.218 2.947 0.69887 0.95305
RegenerationR5 -0.669 2.947 0.21886 0.65355
RegenerationR6 -0.955 2.947 0.10853 0.40794
RegenerationBL 0.02 2.947 0.97908 1.00000
RegenerationTP -0.422 2.947 0.64999 0.98877


Genes with expression patterns similar to MligTC455_53961

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53961 290 6.04 Mlig455_051313

Neo: -

Age: logFC(26M/2M)=-0.591

Region-enriched R2: 2.488/0.02898

TTLL7 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_051313 {REF} {Length: 3404} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=247.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.8]; YheC/D like ATP-grasp [PF14398.8, score=18.8]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [RH, Score=478, Expect=1e-157]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [RH, Score=474, Expect=2e-153]} {Dmel: FBgn0039501, CG5987, [Score=289, Expect=2e-85]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=184, Expect=5e-49]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [RH, Score=408, Expect=4e-128]} {RNA1509_8901} {RNA1310_4651, RNA1509_8901} {RNA1509_8901, RNA815_1757}
2. MligTC455_53960 381 7.93 Mlig455_039523

Neo: -

Age: logFC(26M/2M)=-0.527

Region-enriched R2: 1.863/0.02753

TTLL7 5.646 0.921 0.897 0.959 0.922 0.993 0.954 Mlig455_039523 {REF} {Length: 2811} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=44.5]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=146, Expect=5e-37]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=261, Expect=2e-76]} {Dmel: FBgn0039501, CG5987, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=118, Expect=1e-27]} {RNA1509_8901} {RNA1310_4651} {RNA815_1757}
3. MligTC455_26817 353 7.36 Mlig455_062943

Neo: -

Age: logFC(26M/2M)=-0.515

TTLL10 4.15 0.740 - 0.833 0.815 0.782 0.980 Mlig455_062943 {REF} {Length: 3909} {Pfam: Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=21.8]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [Score=69.7, Expect=2e-12]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [Score=87.4, Expect=9e-19]} {RNA1509_23478} {RNA1310_12709.1} {RNA815_2937}
4. MligTC455_26816 355 7.39 Mlig455_062861

Neo: -

Age: logFC(26M/2M)=-0.333

TTLL10 4.145 0.740 - 0.833 0.813 0.779 0.980 Mlig455_062861 {REF} {Length: 4729} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=173.8]; YheC/D like ATP-grasp [PF14398.8, score=30.2]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=27.4]; Sugar-transfer associated ATP-grasp [PF14397.8, score=20.6]} {Human: ENSG00000162571, TTLL10, tubulin tyrosine ligase like 10, [RH, Score=323, Expect=5e-100]} {Mouse: ENSMUSG00000029074, Ttll10, tubulin tyrosine ligase-like family, member 10, [RH, Score=319, Expect=2e-98]} {Dmel: FBgn0030823, CG8918, [Score=129, Expect=2e-31]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=99.4, Expect=5e-22]} {Smed: dd_Smed_v6_9664_0_1, dd_Smed_v6_9664_0_1, [RH, Score=445, Expect=2e-147]} {RNA1509_23478, RNA1509_31433, RNA1509_39757} {RNA1310_12709.1, RNA1509_23478, RNA1509_31433, RNA1509_39757} {RNA1509_23478, RNA1509_31433, RNA1509_39757, RNA815_2937}
5. MligTC455_28457 1836 38.25 Mlig455_047188, Mlig455_048490

Neo: -

Age: logFC(26M/2M)=-0.228

RSPH10B2 3.544 - - 0.879 0.778 0.929 0.958

Mlig455_047188 {REF} {Length: 3292} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=169.8]} {Human: ENSG00000169402, RSPH10B2, radial spoke head 10 homolog B2, [RH, Score=435, Expect=9e-137]; ENSG00000155026, RSPH10B, radial spoke head 10 homolog B, [RH, Score=431, Expect=3e-135]} {Mouse: ENSMUSG00000075569, Rsph10b, radial spoke head 10 homolog B (Chlamydomonas), [RH, Score=435, Expect=5e-137]} {Dmel: FBgn0050429, CG30429, [Score=88.2, Expect=1e-18]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=77.0, Expect=4e-14]} {Smed: dd_Smed_v6_12762_0_1, dd_Smed_v6_12762_0_1, [RH, Score=524, Expect=5e-171]} {RNA1509_2912} {RNA1310_4817} {RNA815_4683.1}

Mlig455_048490 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: MORN repeat [PF02493.22, score=169.8]} {Human: ENSG00000169402, RSPH10B2, radial spoke head 10 homolog B2, [RH, Score=434, Expect=2e-136]; ENSG00000155026, RSPH10B, radial spoke head 10 homolog B, [RH, Score=429, Expect=1e-134]} {Mouse: ENSMUSG00000075569, Rsph10b, radial spoke head 10 homolog B (Chlamydomonas), [RH, Score=434, Expect=2e-136]} {Dmel: FBgn0050429, CG30429, [Score=88.2, Expect=1e-18]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=77.0, Expect=4e-14]} {Smed: dd_Smed_v6_12762_0_1, dd_Smed_v6_12762_0_1, [RH, Score=525, Expect=1e-171]} {RNA1509_2912} {RNA1310_4817, RNA1509_2912} {RNA1509_2912, RNA815_4683.1}
6. MligTC455_52303 382 7.96 Mlig455_009518

Neo: -

Age: -

Region-enriched R2: 1.953/0.01722

FAM149B1 3.514 - - 0.919 0.747 0.952 0.896 Mlig455_009518 {REF} {Length: 3223} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF3719) [PF12516.10, score=23.9]} {Human: ENSG00000138286, FAM149B1, family with sequence similarity 149 member B1, [RH, Score=79.3, Expect=1e-14]} {Mouse: ENSMUSG00000070044, Fam149a, family with sequence similarity 149, member A, [Score=74.7, Expect=2e-13]} {Smed: dd_Smed_v6_13092_0_1, dd_Smed_v6_13092_0_1, [Score=98.2, Expect=5e-21]} {RNA1509_15304} {RNA1310_4854, RNA1509_15304} {RNA1509_15304, RNA815_5012.1}
7. MligTC455_24516 292 6.08 Mlig455_035506

Neo: -

Age: -

PRKAR1B 3.497 - 0.765 0.842 - 0.936 0.954 Mlig455_035506 {REF} {Length: 3296} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=72.4]} {Human: ENSG00000188191, PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta, [Score=53.9, Expect=7e-07]} {Mouse: ENSMUSG00000025855, Prkar1b, protein kinase, cAMP dependent regulatory, type I beta, [Score=53.5, Expect=7e-07]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00002190, kin-2, cAMP-dependent protein kinase regulatory subunit, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_13623_0_1, dd_Smed_v6_13623_0_1, [Score=373, Expect=3e-118]} {RNA1509_48722} {RNA1310_4914, RNA1509_48722} {RNA1509_48722, RNA815_2637}
8. MligTC455_42812 255 5.31 Mlig455_051711

Neo: -

Age: Down-Up-Down

3.491 - - 0.741 0.887 0.895 0.968 Mlig455_051711 {REF} {Length: 2796} {TRANSSPLICED} {Smed: dd_Smed_v6_11800_0_1, dd_Smed_v6_11800_0_1, [Score=82.0, Expect=8e-16]} {RNA1509_36206} {RNA1310_23933, RNA1509_36206} {RNA1509_36206, RNA815_12504}
9. MligTC455_19702 266 5.54 Mlig455_012020

Neo: -

Age: -

TTC30B 3.468 - - 0.762 0.849 0.877 0.980 Mlig455_012020 {REF} {Length: 2634} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF14559.8, score=73.1]; Tetratricopeptide repeat [PF07719.19, score=53.4]; Tetratricopeptide repeat [PF13424.8, score=39.7]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=38.5]; Tetratricopeptide repeat [PF13432.8, score=37.3]; Tetratricopeptide repeat [PF13174.8, score=31.6]; Tetratricopeptide repeat [PF00515.30, score=27.1]; Tetratricopeptide repeat [PF13428.8, score=26.0]; Tetratricopeptide repeat [PF13181.8, score=25.9]; Tetratricopeptide repeat [PF13176.8, score=21.7]; Tetratricopeptide repeat [PF13371.8, score=20.6]; Outer membrane lipoprotein [PF13525.8, score=20.3]; Putative TPR-like repeat [PF17004.7, score=20.1]} {Human: ENSG00000196659, TTC30B, tetratricopeptide repeat domain 30B, [Score=778, Expect=0.0]; ENSG00000197557, TTC30A, tetratricopeptide repeat domain 30A, [Score=771, Expect=0.0]} {Mouse: ENSMUSG00000075271, Ttc30a1, tetratricopeptide repeat domain 30A1, [Score=778, Expect=0.0]; ENSMUSG00000075273, Ttc30b, tetratricopeptide repeat domain 30B, [Score=778, Expect=0.0]; ENSMUSG00000075272, Ttc30a2, tetratricopeptide repeat domain 30A2, [Score=774, Expect=0.0]} {Dmel: FBgn0032470, CG5142, [Score=515, Expect=1e-175]} {Celegans: WBGene00001117, dyf-1, Tetratricopeptide repeat protein 30 homolog, [Score=568, Expect=0.0]} {Smed: dd_Smed_v6_8798_0_1, dd_Smed_v6_8798_0_1, [Score=865, Expect=0.0]} {RNA1509_12977} {RNA1310_15403, RNA1509_12977} {RNA1509_12977, RNA815_4297}
10. MligTC455_24519 1035 21.55 Mlig455_026505

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.364/0.03756

DNAH10 3.465 - - 0.782 0.951 0.869 0.863 Mlig455_026505 {REF} {Length: 14733} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=521.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=390.5]; P-loop containing dynein motor region D4 [PF12780.9, score=341.0]; Dynein heavy chain C-terminal domain [PF18199.3, score=306.8]; ATP-binding dynein motor region [PF12781.9, score=282.5]; P-loop containing dynein motor region [PF12775.9, score=264.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=214.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=174.9]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=142.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=92.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=81.8]; AAA+ lid domain [PF17857.3, score=63.2]; AAA domain [PF13401.8, score=44.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=34.7]; AAA ATPase domain [PF13191.8, score=31.6]; AAA domain [PF13238.8, score=24.7]; MoxR domain in the MoxR-vWA-beta-propeller ternary systems [PF20030.1, score=21.4]; Sigma-54 interaction domain [PF00158.28, score=21.3]} {Human: ENSG00000281935, DNAH10, dynein axonemal heavy chain 10, [RH, Score=4662, Expect=0.0]} {Mouse: ENSMUSG00000038011, Dnah10, dynein, axonemal, heavy chain 10, [Score=4676, Expect=0.0]} {Dmel: FBgn0013813, Dhc98D, Dynein heavy chain at 89D, [RH, Score=3860, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1408, Expect=0.0]} {Smed: dd_Smed_v6_5169_0_1, dd_Smed_v6_5169_0_1, [RH, Score=4698, Expect=0.0]} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1310_40.1, RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395, RNA815_20}
11. MligTC455_34792 238 4.96 Mlig455_045574

Neo: -

Age: logFC(26M/2M)=-0.239

3.465 - - 0.944 0.718 0.822 0.981 Mlig455_045574 {REF} {Length: 4478} {Smed: dd_Smed_v6_27312_0_1, dd_Smed_v6_27312_0_1, [RH, Score=160, Expect=9e-40]} {RNA1509_6675} {RNA1310_2307, RNA1509_6675} {RNA1509_6675, RNA815_650}
12. MligTC455_34893 231 4.8 Mlig455_066819

Neo: -

Age: Down-Up-Down

CYP2U1 3.461 - 0.763 0.896 0.965 0.837 - Mlig455_066819 {REF} {Length: 1584} {Pfam: Cytochrome P450 [PF00067.24, score=109.5]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=95.5, Expect=9e-24]; ENSG00000186104, CYP2R1, cytochrome P450 family 2 subfamily R member 1, [Score=92.4, Expect=3e-22]; ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=91.3, Expect=9e-22]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=91.3, Expect=6e-22]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=90.5, Expect=1e-21]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=90.5, Expect=1e-21]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=90.1, Expect=1e-21]; ENSMUSG00000030670, Cyp2r1, cytochrome P450, family 2, subfamily r, polypeptide 1, [Score=89.7, Expect=4e-22]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=89.0, Expect=3e-21]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=87.8, Expect=1e-20]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [Score=87.4, Expect=1e-20]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=76.3, Expect=9e-17]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=89.0, Expect=2e-21]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [Score=102, Expect=4e-26]} {RNA1509_39728} {RNA1310_10949.2} {RNA815_7611}
13. MligTC455_28088 224 4.66 Mlig455_062818

Neo: -

Age: Up-Down-Down

FAM57A 3.443 - 0.804 - 0.870 0.789 0.980 Mlig455_062818 {REF} {Length: 3309} {TRANSSPLICED} {tRNA: Lys(TTT), score=88.9} {Pfam: TLC domain [PF03798.18, score=91.3]} {Human: ENSG00000167695, FAM57A, family with sequence similarity 57 member A, [Score=100, Expect=8e-25]} {Mouse: ENSMUSG00000069808, Fam57a, family with sequence similarity 57, member A, [Score=114, Expect=4e-30]} {RNA1509_29800} {RNA1310_23795.1} {RNA815_13618.1}
14. MligTC455_43683 520 10.83 Mlig455_029440

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.407

3.418 - - 0.839 0.724 0.958 0.897 Mlig455_029440 {REF} {Length: 1842} {RNA1509_21217} {RNA1310_16933.1, RNA1509_21217} {RNA1509_21217, RNA815_7959}
15. MligTC455_40158 660 13.75 Mlig455_011040

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.454

Region-enriched R2: 1.509/0.04515

ZMYND12 3.404 0.749 - 0.792 - 0.883 0.980 Mlig455_011040 {REF} {Length: 2385} {Pfam: MYND finger [PF01753.20, score=36.1]; MalT-like TPR region [PF17874.3, score=22.6]; Tetratricopeptide repeat [PF07719.19, score=22.5]; Tetratricopeptide repeat [PF00515.30, score=21.0]; Tetratricopeptide repeat [PF13424.8, score=21.0]} {Human: ENSG00000066185, ZMYND12, zinc finger MYND-type containing 12, [RH, Score=286, Expect=1e-93]} {Mouse: ENSMUSG00000070806, Zmynd12, zinc finger, MYND domain containing 12, [RH, Score=297, Expect=4e-98]} {Smed: dd_Smed_v6_10079_0_1, dd_Smed_v6_10079_0_1, [RH, Score=393, Expect=4e-136]} {RNA1509_3913, RNA1509_42555} {RNA1310_12452, RNA1509_3913, RNA1509_42555} {RNA1509_3913, RNA1509_42555, RNA815_3855}
16. MligTC455_44145 1616 33.67 Mlig455_013447

Neo: -

Age: -

3.397 - - 0.907 0.800 0.738 0.952 Mlig455_013447 {REF} {Length: 841} {RNA1509_20243} {RNA1310_1688.1} {RNA815_1415.1}
17. MligTC455_36043 215 4.49 Mlig455_046412

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.608

Region-enriched R4: 3.299/0.00544

LOXHD1 3.361 - 0.773 0.960 0.811 0.817 - Mlig455_046412 {REF} {Length: 3070} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=52.2]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=75.9, Expect=2e-13]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=76.6, Expect=5e-14]} {Smed: dd_Smed_v6_39713_0_1, dd_Smed_v6_39713_0_1, [RH, Score=81.3, Expect=4e-16]} {RNA1509_25188, RNA1509_53601} {RNA1310_11606, RNA1509_25188, RNA1509_53601} {RNA1509_25188, RNA1509_53601, RNA815_15282}
18. MligTC455_08944 160 3.34 Mlig455_050947

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.619

3.331 - - 0.713 0.712 0.922 0.984 Mlig455_050947 {REF} {Length: 1135} {RNA1310_13460.1} {RNA815_53760}
19. MligTC455_17580 2178 45.37 Mlig455_048028

Neo: -

Age: Down-Up-Up

3.272 - 0.726 - 0.715 0.855 0.976 Mlig455_048028 {REF} {Length: 5222} {RNA1509_12558, RNA1509_43882} {RNA1310_10969, RNA1509_43882} {RNA1509_43882, RNA815_3485.1}
20. MligTC455_40501 68 1.42 Mlig455_011503

Neo: -

Age: Up-Down-Down

SPATA18 3.222 - 0.745 0.723 0.784 0.970 - Mlig455_011503 {REF} {Length: 3947} {Pfam: Mitochondria-eating protein [PF16026.7, score=151.5]} {Human: ENSG00000163071, SPATA18, spermatogenesis associated 18, [Score=174, Expect=2e-47]} {Mouse: ENSMUSG00000029155, Spata18, spermatogenesis associated 18, [Score=174, Expect=4e-48]} {Smed: dd_Smed_v6_6321_0_1, dd_Smed_v6_6321_0_1, [Score=196, Expect=7e-56]} {RNA1509_30652} {RNA1310_42425} {RNA815_16227}
21. MligTC455_22285 679 14.14 Mlig455_019090, Mlig455_064274

Neo: -

Age: -

Region-enriched R2: 1.663/0.01632

INVS 3.206 0.714 - - 0.725 0.787 0.980

Mlig455_019090 {REF} {Length: 5312} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=202.1]; Ankyrin repeats (many copies) [PF13637.8, score=171.0]; Ankyrin repeat [PF00023.32, score=132.7]; Ankyrin repeat [PF13606.8, score=120.3]; Ankyrin repeats (many copies) [PF13857.8, score=107.4]} {Human: ENSG00000119509, INVS, inversin, [Score=155, Expect=1e-37]; ENSG00000151150, ANK3, ankyrin 3, [Score=152, Expect=4e-36]} {Mouse: ENSMUSG00000028344, Invs, inversin, [Score=156, Expect=5e-38]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=152, Expect=3e-36]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=149, Expect=1e-35]} {Dmel: FBgn0260487, CG42534, [RH, Score=293, Expect=1e-80]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [RH, Score=176, Expect=9e-45]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [RH, Score=471, Expect=3e-145]} {RNA1509_45730, RNA1509_6692} {RNA1310_1162.1, RNA1509_45730, RNA1509_6692} {RNA1509_45730, RNA1509_6692, RNA815_2654}

Mlig455_064274 {REF} {Length: 5181} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=202.3]; Ankyrin repeats (many copies) [PF13637.8, score=171.3]; Ankyrin repeat [PF00023.32, score=133.2]; Ankyrin repeat [PF13606.8, score=120.8]; Ankyrin repeats (many copies) [PF13857.8, score=107.9]} {Human: ENSG00000119509, INVS, inversin, [Score=155, Expect=1e-37]; ENSG00000151150, ANK3, ankyrin 3, [Score=151, Expect=6e-36]} {Mouse: ENSMUSG00000028344, Invs, inversin, [Score=156, Expect=6e-38]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=151, Expect=4e-36]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=149, Expect=1e-35]} {Dmel: FBgn0260487, CG42534, [RH, Score=293, Expect=1e-80]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [RH, Score=176, Expect=8e-45]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [RH, Score=471, Expect=2e-145]} {RNA1509_6692} {RNA1310_1162.1} {RNA815_2654}
22. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 2.736 - - 0.938 0.841 0.957 -

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
23. MligTC455_52762 237 4.94 Mlig455_020578

Neo: Irradiation

Age: -

DLC1 2.736 - - - 0.879 0.865 0.992 Mlig455_020578 {REF} {Length: 5812} {Pfam: RhoGAP domain [PF00620.29, score=111.3]; START domain [PF01852.21, score=52.9]} {Human: ENSG00000164741, DLC1, DLC1 Rho GTPase activating protein, [RH, Score=379, Expect=6e-114]; ENSG00000285265, DLC1, DLC1 Rho GTPase activating protein, [RH, Score=379, Expect=5e-111]} {Mouse: ENSMUSG00000031523, Dlc1, deleted in liver cancer 1, [RH, Score=374, Expect=2e-109]} {Dmel: FBgn0285955, cv-c, crossveinless c, [RH, Score=345, Expect=1e-98]} {Celegans: WBGene00001559, gei-1, GEX Interacting protein, [RH, Score=232, Expect=4e-62]} {Smed: dd_Smed_v6_9530_0_1, dd_Smed_v6_9530_0_1, [RH, Score=345, Expect=3e-103]} {RNA1509_36273} {RNA1310_9000} {RNA815_6507}
24. MligTC455_18347 118 2.46 Mlig455_000821

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.590

KCNA1 2.734 - - 0.808 - 0.963 0.963 Mlig455_000821 {REF} {Length: 3163} {Pfam: Ion transport protein [PF00520.33, score=166.1]; BTB/POZ domain [PF02214.24, score=97.8]; Ion channel [PF07885.18, score=48.4]} {Human: ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=611, Expect=0.0]; ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=611, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=610, Expect=0.0]; ENSG00000182255, KCNA4, potassium voltage-gated channel subfamily A member 4, [RH, Score=585, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=611, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=610, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]; ENSMUSG00000042604, Kcna4, potassium voltage-gated channel, shaker-related subfamily, member 4, [RH, Score=587, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=629, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=377, Expect=2e-124]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=707, Expect=0.0]} {RNA1509_47579} {RNA1310_8777} {RNA815_4701}
25. MligTC455_46306 458 9.55 Mlig455_059663

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.355

Region-enriched R2: 2.126/0.00026

PTBP3 2.722 - - 0.918 0.959 0.845 - Mlig455_059663 {REF} {Length: 3410} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=151.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=112.0]; RRM-like domain [PF11835.10, score=52.5]; Occluded RNA-recognition motif [PF16842.7, score=43.5]; RNA binding motif [PF08777.13, score=18.6]} {Human: ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [RH, Score=466, Expect=9e-157]; ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [RH, Score=463, Expect=1e-155]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [RH, Score=462, Expect=9e-156]} {Mouse: ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [RH, Score=468, Expect=2e-157]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [RH, Score=468, Expect=1e-157]; ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [RH, Score=465, Expect=6e-157]} {Dmel: FBgn0011224, heph, hephaestus, [RH, Score=442, Expect=2e-143]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [RH, Score=422, Expect=4e-139]} {Smed: dd_Smed_v6_14748_0_1, dd_Smed_v6_14748_0_1, [RH, Score=340, Expect=2e-107]} {RNA1509_7362} {RNA1310_5320} {RNA815_1604}
26. MligTC455_44782 1105 23.02 Mlig455_014607

Neo: -

Age: -

PGAM5 2.717 - - - 0.873 0.869 0.975 Mlig455_014607 {REF} {Length: 2581} {TRANSSPLICED} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=74.1]} {Human: ENSG00000247077, PGAM5, PGAM family member 5, mitochondrial serine/threonine protein phosphatase, [Score=169, Expect=1e-50]} {Mouse: ENSMUSG00000029500, Pgam5, phosphoglycerate mutase family member 5, [Score=171, Expect=2e-51]} {Dmel: FBgn0023517, Pgam5, Phosphoglycerate mutase 5, [Score=151, Expect=7e-44]} {Celegans: WBGene00019941, pgam-5, Serine/threonine-protein phosphatase Pgam5, mitochondrial, [Score=164, Expect=4e-49]} {Smed: dd_Smed_v6_6361_0_1, dd_Smed_v6_6361_0_1, [Score=160, Expect=5e-48]} {RNA1509_10913} {RNA1310_28905, RNA1509_10913} {RNA1509_10913, RNA815_15585}
27. MligTC455_45837 631 13.15 Mlig455_055002

Neo: -

Age: -

2.717 - - 0.903 0.842 0.972 - Mlig455_055002 {REF} {Length: 821} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
28. MligTC455_32268 289 6.01 Mlig455_033434

Neo: -

Age: -

HMCN1 2.716 - - 0.829 - 0.913 0.974 Mlig455_033434 {REF} {Length: 3936} {Pfam: Immunoglobulin domain [PF13927.8, score=169.9]; Immunoglobulin domain [PF13895.8, score=147.3]; Immunoglobulin I-set domain [PF07679.18, score=142.5]; Immunoglobulin domain [PF00047.27, score=108.6]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=50.3]; Immunoglobulin V-set domain [PF07686.19, score=35.9]; Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain [PF16681.7, score=27.3]; Fibronectin type III domain [PF00041.23, score=25.0]; Immunoglobulin domain [PF18452.3, score=18.9]} {Human: ENSG00000143341, HMCN1, hemicentin 1, [Score=133, Expect=8e-31]} {Mouse: ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=141, Expect=2e-33]} {Dmel: FBgn0000547, ed, echinoid, [RH, Score=248, Expect=1e-67]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=134, Expect=1e-31]} {Smed: dd_Smed_v6_13903_0_1, dd_Smed_v6_13903_0_1, [RH, Score=202, Expect=2e-53]} {RNA1509_34913} {RNA1310_1330.1, RNA1509_34913} {RNA1509_34913, RNA815_5998}
29. MligTC455_45120 345 7.18 Mlig455_064703

Neo: -

Age: logFC(26M/2M)=-0.394

CFAP61 2.7 - - - 0.841 0.886 0.973 Mlig455_064703 {REF} {Length: 4442} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4821) [PF16092.7, score=291.8]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=33.7]} {Human: ENSG00000089101, CFAP61, cilia and flagella associated protein 61, [RH, Score=1009, Expect=0.0]} {Mouse: ENSMUSG00000037143, Cfap61, cilia and flagella associated protein 61, [RH, Score=1006, Expect=0.0]} {Dmel: FBgn0050268, CG30268, [RH, Score=112, Expect=1e-24]} {Smed: dd_Smed_v6_4908_0_1, dd_Smed_v6_4908_0_1, [RH, Score=781, Expect=0.0]} {RNA1509_1314} {RNA1310_1812.1, RNA1509_1314} {RNA1509_1314, RNA815_503}
30. MligTC455_41538 1908 39.76 Mlig455_010187, Mlig455_058608, Mlig455_058684

Neo: -

Age: -

CCDC170 2.684 - - 0.937 0.791 0.956 -

Mlig455_010187 {REF} {Length: 3945} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [RH, Score=283, Expect=1e-83]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [RH, Score=273, Expect=3e-80]} {Dmel: FBgn0263079, CG43338, [RH, Score=117, Expect=9e-27]} {Smed: dd_Smed_v6_10140_0_2, dd_Smed_v6_10140_0_2, [RH, Score=296, Expect=3e-88]} {RNA1509_3115} {RNA1310_2598} {RNA815_746}

Mlig455_058608 {REF} {Length: 3920} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [Score=209, Expect=8e-58]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [Score=224, Expect=2e-63]} {Dmel: FBgn0263079, CG43338, [Score=95.5, Expect=6e-20]} {Smed: dd_Smed_v6_7992_0_1, dd_Smed_v6_7992_0_1, [Score=211, Expect=1e-58]} {RNA1509_3115} {RNA1310_2598} {RNA815_746}

Mlig455_058684 {REF} {Length: 3883} {Human: ENSG00000120262, CCDC170, coiled-coil domain containing 170, [RH, Score=272, Expect=1e-79]} {Mouse: ENSMUSG00000019767, Ccdc170, coiled-coil domain containing 170, [Score=257, Expect=3e-74]} {Dmel: FBgn0263079, CG43338, [RH, Score=108, Expect=8e-24]} {Smed: dd_Smed_v6_7066_0_1, dd_Smed_v6_7066_0_1, [Score=272, Expect=6e-80]} {RNA1509_3115} {RNA1310_2598} {RNA815_746}
31. MligTC455_27649 366 7.62 Mlig455_017718, Mlig455_057045

Neo: -

Age: logFC(26M/2M)=0.439

ADAM9 2.682 - - 0.893 0.830 0.959 -

Mlig455_017718 {REF} {Length: 3325} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=133.0]; Disintegrin [PF00200.25, score=68.9]; Metallo-peptidase family M12 [PF13688.8, score=68.7]; ADAM cysteine-rich [PF08516.14, score=58.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=52.3]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=44.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=32.0]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=272, Expect=2e-78]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=268, Expect=1e-76]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [RH, Score=276, Expect=2e-79]} {Dmel: FBgn0265140, Meltrin, [Score=262, Expect=7e-73]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=263, Expect=9e-75]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=247, Expect=2e-68]} {RNA1509_19133, RNA1509_24635, RNA1509_4260, RNA1509_50111} {RNA1310_4299.1, RNA1509_19133, RNA1509_24635, RNA1509_50111} {RNA1509_19133, RNA1509_24635, RNA1509_50111, RNA815_11215.1}

Mlig455_057045 {REF} {Length: 3286} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=133.0]; Disintegrin [PF00200.25, score=69.2]; Metallo-peptidase family M12 [PF13688.8, score=68.8]; ADAM cysteine-rich [PF08516.14, score=58.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=52.3]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=44.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=32.0]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=273, Expect=2e-78]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=268, Expect=7e-77]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [RH, Score=280, Expect=5e-81]} {Dmel: FBgn0265140, Meltrin, [Score=259, Expect=5e-73]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=263, Expect=8e-75]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=247, Expect=2e-68]} {RNA1509_22944, RNA1509_4260} {RNA1310_4299.1, RNA1509_22944, RNA1509_4260} {RNA1509_22944, RNA1509_4260, RNA815_11215.1}
32. MligTC455_40657 90 1.87 Mlig455_040779

Neo: -

Age: -

CLIP2 2.681 - - 0.920 0.789 0.972 - Mlig455_040779 {REF} {Length: 2164} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=1e-09]} {Dmel: FBgn0036882, CG9279, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
33. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

SYTL4 2.67 - - 0.847 0.860 0.963 - Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
34. MligTC455_51384 557 11.61 Mlig455_025859, Mlig455_025921, Mlig455_025953

Neo: -

Age: logFC(26M/2M)=-0.224

2.664 - - 0.819 - 0.877 0.968

Mlig455_025859 {REF} {Length: 3521} {Pfam: Dynamin family [PF00350.25, score=44.1]; 50S ribosome-binding GTPase [PF01926.25, score=38.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=28.5]; ATPase domain predominantly from Archaea [PF01637.20, score=21.4]; RsgA GTPase [PF03193.18, score=19.5]} {Smed: dd_Smed_v6_6544_0_1, dd_Smed_v6_6544_0_1, [Score=69.3, Expect=9e-12]} {RNA1509_11576} {RNA1310_3511} {RNA815_1113}

Mlig455_025921 {REF} {Length: 3198} {Pfam: Dynamin family [PF00350.25, score=44.4]; 50S ribosome-binding GTPase [PF01926.25, score=39.1]; Elongation factor Tu GTP binding domain [PF00009.29, score=28.7]; ATPase domain predominantly from Archaea [PF01637.20, score=21.5]; RsgA GTPase [PF03193.18, score=19.9]} {Smed: dd_Smed_v6_6544_0_1, dd_Smed_v6_6544_0_1, [Score=68.9, Expect=8e-12]} {RNA1509_58217, RNA1509_59966} {RNA1310_3511, RNA1509_59966} {RNA1509_59966, RNA815_1113}

Mlig455_025953 {REF} {Length: 3561} {Pfam: Dynamin family [PF00350.25, score=44.1]; 50S ribosome-binding GTPase [PF01926.25, score=39.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=29.0]; RsgA GTPase [PF03193.18, score=20.4]; ATPase domain predominantly from Archaea [PF01637.20, score=19.8]} {Smed: dd_Smed_v6_6544_0_1, dd_Smed_v6_6544_0_1, [Score=69.3, Expect=9e-12]} {RNA1509_11576, RNA1509_43753} {RNA1310_3511, RNA1509_43753} {RNA1509_43753, RNA815_1113}
35. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 2.661 - - 0.939 0.755 0.967 -

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
36. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

KY 2.635 - - 0.956 0.753 0.926 -

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
37. MligTC455_20555 325 6.77 Mlig455_035815

Neo: -

Age: -

LRRC56 2.629 - - 0.877 0.794 - 0.958 Mlig455_035815 {REF} {Length: 3489} {TRANSSPLICED} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=35.1]; Leucine rich repeat [PF13855.8, score=30.0]; Leucine-rich repeat [PF14580.8, score=26.7]} {Human: ENSG00000161328, LRRC56, leucine rich repeat containing 56, [RH, Score=222, Expect=2e-64]; ENSG00000273831, LRRC56, leucine rich repeat containing 56, [RH, Score=221, Expect=6e-64]} {Mouse: ENSMUSG00000038637, Lrrc56, leucine rich repeat containing 56, [RH, Score=202, Expect=2e-58]} {Dmel: FBgn0035497, CG14995, [Score=64.3, Expect=1e-10]} {Smed: dd_Smed_v6_10834_0_1, dd_Smed_v6_10834_0_1, [RH, Score=334, Expect=3e-107]} {RNA1509_10058} {RNA1310_11542} {RNA815_9595}
38. MligTC455_33841 898 18.71 Mlig455_004818, Mlig455_004886

Neo: -

Age: logFC(26M/2M)=-0.301

Region-enriched R2: 1.729/0.00165

CDKL1 2.621 - - 0.838 0.828 0.955 -

Mlig455_004818 {REF} {Length: 2858} {Pfam: Protein kinase domain [PF00069.27, score=245.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.2]; RIO1 family [PF01163.24, score=22.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=427, Expect=2e-147]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=4e-145]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=430, Expect=6e-149]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=421, Expect=1e-145]} {Dmel: FBgn0031730, CG7236, [RH, Score=379, Expect=7e-128]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=395, Expect=1e-133]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=478, Expect=1e-167]} {RNA1509_19679} {RNA1310_6686.2} {RNA815_5397}

Mlig455_004886 {REF} {Length: 2943} {Pfam: Protein kinase domain [PF00069.27, score=245.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.0]; RIO1 family [PF01163.24, score=22.4]; Haspin like kinase domain [PF12330.10, score=17.8]; ABC1 atypical kinase-like domain [PF03109.18, score=17.7]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=428, Expect=6e-148]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=4e-146]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=431, Expect=2e-149]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=422, Expect=6e-146]} {Dmel: FBgn0031730, CG7236, [RH, Score=380, Expect=3e-128]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=392, Expect=2e-132]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=479, Expect=5e-168]} {RNA1509_19679} {RNA1310_6686.2} {RNA815_5397}
39. MligTC455_38922 1324 27.57 Mlig455_055899

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.333

MX2 2.619 - - 0.760 - 0.871 0.988 Mlig455_055899 {REF} {Length: 3320} {Pfam: Dynamin central region [PF01031.22, score=177.8]; Dynamin family [PF00350.25, score=125.7]; Dynamin GTPase effector domain [PF02212.20, score=46.3]; 50S ribosome-binding GTPase [PF01926.25, score=21.2]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=308, Expect=3e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=182, Expect=9e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=176, Expect=6e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=198, Expect=2e-53]} {RNA1509_37170, RNA1509_6400} {RNA1310_6542.1, RNA1509_37170, RNA1509_6400} {RNA1509_37170, RNA1509_6400, RNA815_1426.1}
40. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

2.618 - 0.778 - 0.883 0.957 - Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
41. MligTC455_43110 746 15.54 Mlig455_029622

Neo: -

Age: -

Region-enriched R2: 1.632/0.03045

ARRDC2 2.615 - - - 0.804 0.856 0.955 Mlig455_029622 {REF} {Length: 1778} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=52.7]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=39.2]} {Human: ENSG00000105643, ARRDC2, arrestin domain containing 2, [Score=76.6, Expect=5e-15]} {Mouse: ENSMUSG00000110906, Arrdc2, arrestin domain containing 2, [Score=84.7, Expect=7e-18]; ENSMUSG00000002910, Arrdc2, arrestin domain containing 2, [Score=84.7, Expect=7e-18]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=76.3, Expect=2e-15]} {Celegans: WBGene00011732, arrd-17, Arrestin domain-containing protein 17, [Score=60.5, Expect=4e-10]} {Smed: dd_Smed_v6_8715_0_1, dd_Smed_v6_8715_0_1, [Score=51.6, Expect=3e-07]} {RNA1509_45476} {RNA1310_16251} {RNA815_9075}
42. MligTC455_21640 262 5.46 Mlig455_052657

Neo: -

Age: -

SLC6A5 2.611 - - - 0.821 0.812 0.978 Mlig455_052657 {REF} {Length: 4833} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=583.6]; BTB/POZ domain [PF00651.33, score=59.5]; BTB And C-terminal Kelch [PF07707.17, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=316, Expect=2e-92]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=315, Expect=5e-92]} {Dmel: FBgn0034911, CG5549, [Score=313, Expect=5e-89]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=228, Expect=2e-63]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=273, Expect=1e-78]} {RNA1509_27437} {RNA1310_7302.1} {RNA815_3821}
43. MligTC455_45865 1422 29.62 Mlig455_044968, Mlig455_044981, Mlig455_044993, Mlig455_055500

Neo: -

Age: -

Region-enriched R2: 2.439/0.00202

ANK2, ANK3 2.604 - - 0.951 0.729 0.924 -

Mlig455_044968 {REF} {Length: 2222} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=114.6]; Ankyrin repeat [PF00023.32, score=97.7]; Ankyrin repeats (many copies) [PF13857.8, score=85.9]; Ankyrin repeat [PF13606.8, score=79.3]; Ankyrin repeats (many copies) [PF13637.8, score=73.3]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=112, Expect=3e-25]; ENSG00000145362, ANK2, ankyrin 2, [Score=112, Expect=2e-25]; ENSG00000131503, ANKHD1, ankyrin repeat and KH domain containing 1, [Score=107, Expect=9e-24]; ENSG00000254996, ANKHD1-EIF4EBP3, ANKHD1-EIF4EBP3 readthrough, [Score=107, Expect=1e-23]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=114, Expect=4e-26]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=114, Expect=2e-26]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=103, Expect=7e-23]} {Smed: dd_Smed_v6_10835_0_1, dd_Smed_v6_10835_0_1, [Score=105, Expect=6e-24]} {RNA1509_57010} {RNA1310_16152} {RNA815_19238}

Mlig455_044981 {REF} {Length: 7748} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=84.4]; Ankyrin repeat [PF00023.32, score=67.2]; Ankyrin repeats (many copies) [PF13857.8, score=42.8]; Ankyrin repeat [PF13606.8, score=40.9]; Ankyrin repeats (many copies) [PF13637.8, score=23.4]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=62.4, Expect=2e-10]; ENSG00000146926, ASB10, ankyrin repeat and SOCS box containing 10, [Score=62.0, Expect=3e-10]; ENSG00000151150, ANK3, ankyrin 3, [Score=61.6, Expect=5e-10]; ENSG00000029534, ANK1, ankyrin 1, [Score=59.3, Expect=3e-09]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=65.9, Expect=1e-11]; ENSMUSG00000038204, Asb10, ankyrin repeat and SOCS box-containing 10, [Score=63.2, Expect=7e-11]} {Dmel: FBgn0031473, CG3104, [Score=59.7, Expect=5e-10]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=52.4, Expect=2e-07]} {Smed: dd_Smed_v6_9936_0_1, dd_Smed_v6_9936_0_1, [Score=62.8, Expect=5e-11]} {RNA1509_59330} {RNA1310_2367} {RNA815_1531}

Mlig455_044993 {REF} {Length: 2286} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=154.1]; Ankyrin repeat [PF00023.32, score=97.7]; Ankyrin repeats (many copies) [PF13857.8, score=85.8]; Ankyrin repeat [PF13606.8, score=79.3]; Ankyrin repeats (many copies) [PF13637.8, score=73.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=112, Expect=3e-25]; ENSG00000145362, ANK2, ankyrin 2, [Score=111, Expect=5e-25]; ENSG00000254996, ANKHD1-EIF4EBP3, ANKHD1-EIF4EBP3 readthrough, [Score=107, Expect=1e-23]; ENSG00000131503, ANKHD1, ankyrin repeat and KH domain containing 1, [Score=107, Expect=9e-24]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=113, Expect=8e-26]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=108, Expect=4e-24]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=115, Expect=2e-26]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=103, Expect=1e-22]} {Smed: dd_Smed_v6_10835_0_1, dd_Smed_v6_10835_0_1, [Score=105, Expect=1e-23]} {RNA1509_28218} {RNA1310_16152} {RNA815_19238}

Mlig455_055500 {REF} {Length: 3956} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=114.6]; Ankyrin repeat [PF00023.32, score=97.7]; Ankyrin repeats (many copies) [PF13857.8, score=85.9]; Ankyrin repeat [PF13606.8, score=79.3]; Ankyrin repeats (many copies) [PF13637.8, score=73.3]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=112, Expect=3e-25]; ENSG00000145362, ANK2, ankyrin 2, [Score=112, Expect=2e-25]; ENSG00000131503, ANKHD1, ankyrin repeat and KH domain containing 1, [Score=107, Expect=9e-24]; ENSG00000254996, ANKHD1-EIF4EBP3, ANKHD1-EIF4EBP3 readthrough, [Score=107, Expect=1e-23]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=114, Expect=4e-26]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=114, Expect=2e-26]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=103, Expect=7e-23]} {Smed: dd_Smed_v6_10835_0_1, dd_Smed_v6_10835_0_1, [Score=105, Expect=6e-24]} {RNA1509_28218, RNA1509_57010} {RNA1310_15834, RNA1509_28218, RNA1509_57010} {RNA1509_28218, RNA1509_57010, RNA815_19238}
44. MligTC455_35997 277 5.76 Mlig455_067328

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.880

AK5 2.597 - - 0.746 - 0.881 0.970 Mlig455_067328 {REF} {Length: 2734} {TRANSSPLICED} {Human: ENSG00000154027, AK5, adenylate kinase 5, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [Score=49.7, Expect=2e-06]} {RNA1509_17110} {RNA1310_19485, RNA1509_17110} {RNA1509_17110, RNA815_14117}
45. MligTC455_40999 200 4.16 Mlig455_032893

Neo: -

Age: -

2.593 - - 0.965 0.726 0.902 - Mlig455_032893 {REF} {Length: 1803} {TRANSSPLICED} {Pfam: Glutathione S-transferase, N-terminal domain [PF13409.8, score=65.0]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=40.2]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=35.4]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=21.1]; Glutathione S-transferase, C-terminal domain [PF14497.8, score=21.1]} {RNA1509_21804} {RNA1310_17102.1} {RNA815_6006.1}
46. MligTC455_47160 747 15.56 Mlig455_021750

Neo: -

Age: logFC(26M/2M)=-0.246

FAM184A 2.587 - - 0.701 0.971 0.915 - Mlig455_021750 {REF} {Length: 3705} {Pfam: Family with sequence similarity 184, A and B [PF15665.7, score=130.1]} {Human: ENSG00000111879, FAM184A, family with sequence similarity 184 member A, [RH, Score=340, Expect=5e-99]} {Mouse: ENSMUSG00000019856, Fam184a, family with sequence similarity 184, member A, [RH, Score=308, Expect=7e-88]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=60.8, Expect=5e-09]} {Smed: dd_Smed_v6_16975_0_1, dd_Smed_v6_16975_0_1, [RH, Score=264, Expect=3e-73]} {RNA1509_5806} {RNA1310_3258.1, RNA1509_5806} {RNA1509_5806, RNA815_936}
47. MligTC455_41118 1399 29.15 Mlig455_058900, Mlig455_058904

Neo: -

Age: -

WDR78 2.584 - - - 0.811 0.816 0.957

Mlig455_058900 {REF} {Length: 2776} {Pfam: WD domain, G-beta repeat [PF00400.34, score=52.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=36.7]} {Human: ENSG00000152763, WDR78, WD repeat domain 78, [RH, Score=447, Expect=9e-145]} {Mouse: ENSMUSG00000035126, Wdr78, WD repeat domain 78, [RH, Score=427, Expect=2e-137]} {Dmel: FBgn0263988, Dic61B, Dynein intermediate chain at 61B, [RH, Score=178, Expect=9e-47]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=97.4, Expect=1e-20]} {Smed: dd_Smed_v6_8721_0_1, dd_Smed_v6_8721_0_1, [RH, Score=606, Expect=0.0]} {RNA1509_18637} {RNA1310_6865} {RNA815_2311}

Mlig455_058904 {REF} {Length: 2779} {Pfam: WD domain, G-beta repeat [PF00400.34, score=52.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=36.7]} {Human: ENSG00000152763, WDR78, WD repeat domain 78, [RH, Score=444, Expect=3e-143]} {Mouse: ENSMUSG00000035126, Wdr78, WD repeat domain 78, [RH, Score=423, Expect=6e-136]} {Dmel: FBgn0263988, Dic61B, Dynein intermediate chain at 61B, [RH, Score=178, Expect=9e-47]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=97.1, Expect=1e-20]} {Smed: dd_Smed_v6_8721_0_1, dd_Smed_v6_8721_0_1, [RH, Score=603, Expect=0.0]} {RNA1509_18637} {RNA1310_6865, RNA1509_18637} {RNA1509_18637, RNA815_2311}
48. MligTC455_43972 1061 22.11 Mlig455_047704

Neo: -

Age: -

2.577 - - 0.779 0.827 0.971 - Mlig455_047704 {REF} {Length: 2155} {TRANSSPLICED} {RNA1509_7618} {RNA1310_9007} {RNA815_27926.1}
49. MligTC455_23643 406 8.46 Mlig455_067289

Neo: -

Age: Down-Up-Up

STK33 2.576 - - - 0.801 0.798 0.977 Mlig455_067289 {REF} {Length: 2596} {Pfam: Protein kinase domain [PF00069.27, score=206.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=137.9]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=22.3]} {Human: ENSG00000130413, STK33, serine/threonine kinase 33, [Score=184, Expect=7e-53]} {Mouse: ENSMUSG00000031027, Stk33, serine/threonine kinase 33, [Score=190, Expect=4e-55]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=137, Expect=2e-36]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=129, Expect=5e-34]} {Smed: dd_Smed_v6_12461_0_1, dd_Smed_v6_12461_0_1, [RH, Score=231, Expect=1e-72]} {RNA1509_36009} {RNA1310_11665} {RNA815_6928}
50. MligTC455_44588 393 8.19 Mlig455_029075

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.404

CASP8 2.573 - - 0.807 0.801 0.965 - Mlig455_029075 {REF} {Length: 2730} {Pfam: Caspase domain [PF00656.24, score=122.9]; Ankyrin repeats (3 copies) [PF12796.9, score=78.1]; Ankyrin repeats (many copies) [PF13637.8, score=65.6]; Ankyrin repeat [PF13606.8, score=61.3]; Ankyrin repeats (many copies) [PF13857.8, score=58.2]; Ankyrin repeat [PF00023.32, score=55.5]} {Human: ENSG00000064012, CASP8, caspase 8, [RH, Score=183, Expect=1e-50]} {Mouse: ENSMUSG00000026029, Casp8, caspase 8, [RH, Score=194, Expect=5e-55]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=149, Expect=4e-40]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=128, Expect=5e-33]} {Smed: dd_Smed_v6_4986_0_1, dd_Smed_v6_4986_0_1, [Score=127, Expect=3e-33]} {RNA1509_39135, RNA1509_56179} {RNA1310_8056, RNA1509_39135, RNA1509_56179} {RNA1509_39135, RNA1509_56179, RNA815_3832.1}
51. MligTC455_29828 3825 79.69 Mlig455_005927, Mlig455_028571

Neo: -

Age: -

Region-enriched R2: 2.078/0.00752

AOX1 2.572 - - 0.808 0.810 0.954 -

Mlig455_005927 {REF} {Length: 5419} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=461, Expect=1e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=454, Expect=4e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=468, Expect=2e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=449, Expect=1e-135]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345} {RNA1310_1703.1, RNA1509_1345} {RNA1509_1345, RNA815_528.1}

Mlig455_028571 {REF} {Length: 5081} {Pfam: Molybdopterin-binding domain of aldehyde dehydrogenase [PF02738.20, score=393.8]; [2Fe-2S] binding domain [PF01799.22, score=95.8]; FAD binding domain in molybdopterin dehydrogenase [PF00941.23, score=88.5]; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain [PF01315.24, score=82.6]; CO dehydrogenase flavoprotein C-terminal domain [PF03450.19, score=60.0]; 2Fe-2S iron-sulfur cluster binding domain [PF00111.29, score=21.6]} {Human: ENSG00000138356, AOX1, aldehyde oxidase 1, [Score=459, Expect=5e-139]; ENSG00000158125, XDH, xanthine dehydrogenase, [Score=453, Expect=6e-137]} {Mouse: ENSMUSG00000024066, Xdh, xanthine dehydrogenase, [Score=467, Expect=3e-142]; ENSMUSG00000063558, Aox1, aldehyde oxidase 1, [Score=450, Expect=9e-136]} {Dmel: FBgn0267408, AOX1, Aldehyde oxidase 1, [Score=665, Expect=0.0]} {Celegans: WBGene00010083, xhd-1, [Score=506, Expect=1e-156]} {RNA1509_1345, RNA1509_30386} {RNA1310_1703.1, RNA1509_30386} {RNA1509_30386, RNA815_528.1}
52. MligTC455_18964 466 9.7 Mlig455_010572

Neo: -

Age: Down-Up-Up

STK38L 2.57 - 0.742 0.868 - 0.960 - Mlig455_010572 {REF} {Length: 1993} {Pfam: Protein kinase domain [PF00069.27, score=146.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=75.4]; ABC1 atypical kinase-like domain [PF03109.18, score=32.4]; Phosphotransferase enzyme family [PF01636.25, score=19.9]} {Human: ENSG00000211455, STK38L, serine/threonine kinase 38 like, [Score=400, Expect=3e-139]; ENSG00000112079, STK38, serine/threonine kinase 38, [Score=400, Expect=8e-139]} {Mouse: ENSMUSG00000024006, Stk38, serine/threonine kinase 38, [Score=402, Expect=2e-142]; ENSMUSG00000001630, Stk38l, serine/threonine kinase 38 like, [Score=402, Expect=8e-140]} {Dmel: FBgn0003744, trc, tricornered, [Score=397, Expect=2e-138]} {Celegans: WBGene00004727, sax-1, Serine/threonine-protein kinase sax-1, [Score=367, Expect=3e-126]} {Smed: dd_Smed_v6_6462_0_2, dd_Smed_v6_6462_0_2, [Score=412, Expect=2e-142]} {RNA1509_22842} {RNA1310_31611, RNA1509_22842} {RNA1509_22842, RNA815_4455}
53. MligTC455_22761 288 6.01 Mlig455_005521

Neo: -

Age: -

ELOVL4 2.569 - - 0.878 0.727 0.964 - Mlig455_005521 {REF} {Length: 1592} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=138.3]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [Score=220, Expect=1e-70]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [Score=216, Expect=1e-69]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [Score=145, Expect=2e-42]} {Celegans: WBGene00001244, elo-6, Elongation of very long chain fatty acids protein 6, [Score=52.8, Expect=4e-08]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [Score=215, Expect=7e-70]} {RNA1509_11261} {RNA1310_42181} {RNA815_6649.1}
54. MligTC455_43971 1049 21.85 Mlig455_014401

Neo: -

Age: logFC(26M/2M)=-0.330

NEK1 2.569 - - 0.759 0.835 0.975 - Mlig455_014401 {REF} {Length: 2439} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=118.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=68.0]; Kinase-like [PF14531.8, score=20.7]} {Human: ENSG00000137601, NEK1, NIMA related kinase 1, [Score=111, Expect=1e-24]} {Mouse: ENSMUSG00000049897, Stkld1, serine/threonine kinase-like domain containing 1, [RH, Score=142, Expect=3e-35]} {Dmel: FBgn0029970, Nek2, [Score=68.9, Expect=8e-12]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=89.4, Expect=3e-18]} {Smed: dd_Smed_v6_10144_0_2, dd_Smed_v6_10144_0_2, [Score=100, Expect=7e-22]} {RNA1509_7618} {RNA1310_9007, RNA1509_7618} {RNA1509_7618, RNA815_6823}
55. MligTC455_24712 208 4.32 Mlig455_044659

Neo: -

Age: -

2.567 - - 0.702 - 0.875 0.990 Mlig455_044659 {REF} {Length: 1720} {NoTransDecoderORF} {RNA1310_99438}
56. MligTC455_35416 312 6.5 Mlig455_025858

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.218/0.01756

2.565 - - 0.958 0.710 0.897 - Mlig455_025858 {REF} {Length: 2565} {RNA1509_8462} {RNA1310_23985, RNA1509_8462} {RNA1509_8462, RNA815_9218.1}
57. MligTC455_19812 192 3.99 Mlig455_017616

Neo: -

Age: -

2.55 - 0.731 0.832 - - 0.987 Mlig455_017616 {REF} {Length: 579} {TRANSSPLICED} {RNA1509_45712} {RNA1310_38057.2} {RNA815_23034.1}
58. MligTC455_51933 583 12.15 Mlig455_024511

Neo: -

Age: logFC(26M/2M)=-0.429

Region-enriched R2: 2.089/0.00081

CBSL 2.546 - - 0.836 0.748 0.962 - Mlig455_024511 {REF} {Length: 1959} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=138.0]; CBS domain [PF00571.30, score=48.9]} {Human: ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=463, Expect=3e-160]; ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=463, Expect=3e-160]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=467, Expect=6e-162]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=327, Expect=2e-107]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=264, Expect=2e-81]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=511, Expect=6e-180]} {RNA1509_36721} {RNA1310_10809} {RNA815_3797.1}
59. MligTC455_28521 992 20.67 Mlig455_046502

Neo: -

Age: -

2.544 - - 0.824 0.952 0.768 - Mlig455_046502 {REF} {Length: 2752} {Dmel: FBgn0031174, CG1486, [Score=81.3, Expect=3e-17]} {Celegans: WBGene00007593, C14H10.3, [Score=87.4, Expect=3e-19]} {Smed: dd_Smed_v6_8663_0_1, dd_Smed_v6_8663_0_1, [Score=84.0, Expect=3e-18]} {RNA1509_19144} {RNA1310_30735} {RNA815_1517}
60. MligTC455_53642 1691 35.23 Mlig455_016919, Mlig455_017019

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.430

Region-specific R2: 1.934

Regeneration-downregulated BL: -2.204

Regeneration-depleted BL: -2.204

AC013470.2 2.539 - - 0.953 0.784 0.802 -

Mlig455_016919 {REF} {Length: 1485} {Human: ENSG00000226690, AC013470.2, uncharacterized LOC102725191, [RH, Score=81.6, Expect=2e-17]} {Smed: dd_Smed_v6_9968_0_1, dd_Smed_v6_9968_0_1, [RH, Score=137, Expect=6e-39]} {RNA1509_15243, RNA1509_21629} {RNA1310_24799.1, RNA1509_15243, RNA1509_21629} {RNA1509_15243, RNA1509_21629, RNA815_10515.1}

Mlig455_017019 {REF} {Length: 1382} {Human: ENSG00000226690, AC013470.2, uncharacterized LOC102725191, [Score=58.5, Expect=4e-10]} {Smed: dd_Smed_v6_9968_0_1, dd_Smed_v6_9968_0_1, [Score=82.0, Expect=5e-19]} {RNA1509_15243} {RNA1310_24799.1} {RNA815_10515.1}
61. MligTC455_40991 373 7.77 Mlig455_012838

Neo: -

Age: Up-Down-Up

RP1 2.532 - - 0.854 0.953 0.725 - Mlig455_012838 {REF} {Length: 9664} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=188.4]; Doublecortin [PF03607.19, score=102.1]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=419, Expect=3e-120]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=414, Expect=7e-119]} {Dmel: FBgn0261387, CG17528, [Score=68.9, Expect=6e-11]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [Score=75.1, Expect=5e-13]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=480, Expect=2e-142]} {RNA1509_42150} {RNA1310_1407} {RNA815_6255}
62. MligTC455_33876 123 2.56 Mlig455_030510

Neo: -

Age: -

2.531 - - - 0.747 0.789 0.995 Mlig455_030510 {REF} {Length: 1004} {RNA1509_42280} {RNA1310_51836} {RNA815_8810.1}
63. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

TRPM3 2.518 - 0.729 - 0.828 0.961 -

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
64. MligTC455_47875 72 1.5 Mlig455_067941

Neo: -

Age: -

2.517 - - 0.816 0.751 0.950 - Mlig455_067941 {REF} {Length: 1399} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.8, Expect=7e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
65. MligTC455_28524 1043 21.72 Mlig455_046600

Neo: -

Age: logFC(26M/2M)=-0.185

PDXDC1 2.514 - - 0.816 0.964 0.734 - Mlig455_046600 {REF} {Length: 4710} {TRANSSPLICED} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=48.8]} {Human: ENSG00000275498, PDXDC1, pyridoxal dependent decarboxylase domain containing 1, [Score=149, Expect=3e-36]; ENSG00000179889, PDXDC1, pyridoxal dependent decarboxylase domain containing 1, [Score=149, Expect=3e-36]; ENSG00000276709, PDXDC1, pyridoxal dependent decarboxylase domain containing 1, [Score=145, Expect=2e-36]} {Mouse: ENSMUSG00000022680, Pdxdc1, pyridoxal-dependent decarboxylase domain containing 1, [Score=146, Expect=1e-35]} {Dmel: FBgn0031174, CG1486, [RH, Score=107, Expect=2e-23]} {Celegans: WBGene00007593, C14H10.3, [RH, Score=107, Expect=2e-23]} {Smed: dd_Smed_v6_8663_0_1, dd_Smed_v6_8663_0_1, [RH, Score=290, Expect=6e-85]} {RNA1509_57468, RNA1509_7244} {RNA1310_4258.1, RNA1509_57468, RNA1509_7244} {RNA1509_57468, RNA1509_7244, RNA815_1517}
66. MligTC455_29164 899 18.73 Mlig455_006856

Neo: -

Age: Down-Up-Up

ANKRD42 2.502 - 0.742 - 0.781 0.979 - Mlig455_006856 {REF} {Length: 2038} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=124.3]; Ankyrin repeats (3 copies) [PF12796.9, score=118.0]; Ankyrin repeats (many copies) [PF13857.8, score=106.6]; Ankyrin repeat [PF13606.8, score=85.3]; Ankyrin repeat [PF00023.32, score=69.9]} {Human: ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [RH, Score=493, Expect=2e-170]} {Mouse: ENSMUSG00000041343, Ankrd42, ankyrin repeat domain 42, [RH, Score=491, Expect=1e-169]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=143, Expect=1e-35]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=125, Expect=4e-30]} {Smed: dd_Smed_v6_10615_0_1, dd_Smed_v6_10615_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_29991} {RNA1310_12980.1} {RNA815_2353.1}
67. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 2.5 - - 0.812 0.732 0.956 - Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
68. MligTC455_43528 1273 26.52 Mlig455_068411

Neo: -

Age: Down-Up-Up

2.497 - - 0.720 0.826 0.951 - Mlig455_068411 {REF} {Length: 842} {Pfam: Pancreatic hormone peptide [PF00159.20, score=37.0]} {RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1310_43859, RNA1509_15391, RNA1509_36078, RNA1509_47628} {RNA1509_15391, RNA1509_36078, RNA1509_47628, RNA815_26881}
69. MligTC455_17499 135 2.81 Mlig455_000190, Mlig455_067703

Neo: -

Age: -

ANKRD44 2.494 - - 0.823 0.704 0.967 -

Mlig455_000190 {REF} {Length: 1504} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=86.3]; Ankyrin repeats (many copies) [PF13637.8, score=73.9]; Ankyrin repeats (many copies) [PF13857.8, score=53.6]; Ankyrin repeat [PF00023.32, score=49.1]; Ankyrin repeat [PF13606.8, score=45.9]} {Human: ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=78.2, Expect=1e-14]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=75.5, Expect=5e-14]} {Smed: dd_Smed_v6_21003_0_1, dd_Smed_v6_21003_0_1, [Score=59.7, Expect=3e-09]} {RNA1509_51450} {RNA1310_16797} {RNA815_9033}

Mlig455_067703 {REF} {Length: 901} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=25.4]; Ankyrin repeats (many copies) [PF13637.8, score=21.9]} {RNA1509_51450} {RNA1310_16797} {RNA815_9033}
70. MligTC455_17267 266 5.55 Mlig455_017106

Neo: -

Age: logFC(26M/2M)=-0.337

OTOP2 2.479 0.725 - - - 0.771 0.983 Mlig455_017106 {REF} {Length: 3746} {Pfam: Otopetrin [PF03189.15, score=249.6]} {Human: ENSG00000183034, OTOP2, otopetrin 2, [Score=58.9, Expect=2e-08]} {Mouse: ENSMUSG00000050201, Otop2, otopetrin 2, [Score=68.2, Expect=2e-11]} {Dmel: FBgn0259150, CG42265, [Score=181, Expect=4e-47]} {Celegans: WBGene00017449, otpl-3, OToPetrin-Like, [Score=114, Expect=2e-26]} {Smed: dd_Smed_v6_13612_0_2, dd_Smed_v6_13612_0_2, [RH, Score=297, Expect=2e-91]} {RNA1509_17427} {RNA1310_8650, RNA1509_17427} {RNA1509_17427, RNA815_9942}
71. MligTC455_19959 364 7.57 Mlig455_014329

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.145

Region-enriched R5: 1.828/0.03883

PHYHD1 2.476 - - 0.755 0.733 - 0.988 Mlig455_014329 {REF} {Length: 1349} {TRANSSPLICED} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=167.1]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [Score=204, Expect=2e-64]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [Score=194, Expect=2e-60]} {Dmel: FBgn0037819, CG14688, [Score=167, Expect=4e-50]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [Score=182, Expect=2e-56]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [Score=214, Expect=1e-68]} {RNA1509_27946, RNA1509_32462, RNA1509_42101} {RNA1310_30765.1, RNA1509_27946, RNA1509_32462, RNA1509_42101} {RNA1509_27946, RNA1509_32462, RNA1509_42101, RNA815_12227}
72. MligTC455_21382 1874 39.04 Mlig455_004691, Mlig455_004766, Mlig455_004851

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.455

Region-enriched R2: 1.848/0.00119

CEP164 2.476 - - 0.961 0.797 0.718 -

Mlig455_004691 {REF} {Length: 3647} {Pfam: WW domain [PF00397.28, score=27.1]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=119, Expect=2e-27]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=118, Expect=2e-27]} {Dmel: FBgn0030716, CG9170, [Score=87.0, Expect=2e-17]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=115, Expect=7e-27]} {RNA1509_14489, RNA1509_33857, RNA1509_43099} {RNA1310_8537, RNA1509_14489, RNA1509_33857, RNA1509_43099} {RNA1509_14489, RNA1509_33857, RNA1509_43099, RNA815_4051}

Mlig455_004766 {REF} {Length: 3501} {Pfam: WW domain [PF00397.28, score=27.8]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=118, Expect=4e-27]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=118, Expect=3e-27]} {Dmel: FBgn0030716, CG9170, [Score=87.8, Expect=9e-18]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=116, Expect=2e-27]} {RNA1509_14489, RNA1509_41953} {RNA1310_8872, RNA1509_41953} {RNA1509_41953, RNA815_4051}

Mlig455_004851 {REF} {Length: 2227} {Pfam: WW domain [PF00397.28, score=27.7]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=118, Expect=4e-27]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=117, Expect=5e-27]} {Dmel: FBgn0030716, CG9170, [Score=86.3, Expect=3e-17]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=116, Expect=3e-27]} {RNA1509_14489} {RNA1310_8872} {RNA815_4051}
73. MligTC455_46255 2218 46.21 Mlig455_024833

Neo: -

Age: logFC(26M/2M)=-0.329

CASC1 2.468 - 0.703 - 0.810 0.955 - Mlig455_024833 {REF} {Length: 2822} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=170.2]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=30.7]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=293, Expect=5e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=82.4, Expect=8e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1} {RNA815_2139}
74. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 2.464 - - 0.729 0.776 0.959 - Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
75. MligTC455_47874 67 1.4 Mlig455_000340

Neo: -

Age: -

2.461 - - 0.806 0.705 0.950 - Mlig455_000340 {REF} {Length: 1412} {Smed: dd_Smed_v6_3944_0_1, dd_Smed_v6_3944_0_1, [Score=97.4, Expect=9e-26]} {RNA1509_55952} {RNA1310_12426} {RNA815_33214}
76. MligTC455_43667 251 5.24 Mlig455_070631

Neo: -

Age: Down-Down-Up

KY 2.457 - - 0.709 0.775 0.973 - Mlig455_070631 {REF} {Length: 5010} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=151, Expect=4e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=2e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=136, Expect=4e-32]} {RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1310_2203, RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1509_26818, RNA1509_52206, RNA1509_7582, RNA815_6135}
77. MligTC455_32754 154 3.21 Mlig455_058773

Neo: -

Age: Down-Down-Up

2.453 - - 0.721 - 0.751 0.981 Mlig455_058773 {REF} {Length: 3692} {RNA1509_27726, RNA1509_37478} {RNA1310_34949, RNA1509_27726, RNA1509_37478} {RNA1509_27726, RNA1509_37478, RNA815_47137}
78. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 2.452 - - 0.707 0.760 0.985 -

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
79. MligTC455_50567 146 3.04 Mlig455_012858

Neo: -

Age: -

Region-specific R2: 6.162

Region-enriched R2: 5.988/0.01054

2.451 - - 0.716 0.766 0.969 - Mlig455_012858 {REF} {Length: 1282} {Pfam: F5/8 type C domain [PF00754.27, score=27.5]} {Smed: dd_Smed_v6_36585_0_1, dd_Smed_v6_36585_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1310_34633} {RNA815_12537}
80. MligTC455_26611 643 13.39 Mlig455_024673

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.538/0.03428

RAB39B 2.439 - - - 0.750 0.726 0.963 Mlig455_024673 {REF} {Length: 2857} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=159.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=92.8]; ADP-ribosylation factor family [PF00025.23, score=40.5]; 50S ribosome-binding GTPase [PF01926.25, score=28.9]} {Human: ENSG00000155961, RAB39B, RAB39B, member RAS oncogene family, [RH, Score=189, Expect=4e-60]; ENSG00000179331, RAB39A, RAB39A, member RAS oncogene family, [RH, Score=187, Expect=2e-59]} {Mouse: ENSMUSG00000055069, Rab39, RAB39, member RAS oncogene family, [RH, Score=190, Expect=8e-61]; ENSMUSG00000031202, Rab39b, RAB39B, member RAS oncogene family, [RH, Score=189, Expect=3e-60]} {Dmel: FBgn0029959, Rab39, [RH, Score=201, Expect=3e-65]} {Celegans: WBGene00004286, rab-39, RAB family, [RH, Score=197, Expect=2e-63]} {Smed: dd_Smed_v6_3651_0_1, dd_Smed_v6_3651_0_1, [RH, Score=216, Expect=4e-71]} {RNA1509_26640, RNA1509_58665} {RNA1310_33935, RNA1509_26640, RNA1509_58665} {RNA1509_26640, RNA1509_58665, RNA815_16719}
81. MligTC455_22199 446 9.28 Mlig455_054328

Neo: -

Age: logFC(26M/2M)=-0.358

DCDC1 2.435 - - - 0.760 0.702 0.973 Mlig455_054328 {REF} {Length: 7417} {Pfam: Cep120 protein [PF12416.10, score=36.0]; Doublecortin [PF03607.19, score=29.7]} {Human: ENSG00000170959, DCDC1, doublecortin domain containing 1, [Score=132, Expect=7e-32]} {Smed: dd_Smed_v6_11770_0_1, dd_Smed_v6_11770_0_1, [Score=213, Expect=3e-59]} {RNA1509_1192, RNA1509_53568} {RNA1310_347, RNA1509_53568} {RNA1509_53568, RNA815_115}
82. MligTC455_19958 380 7.92 Mlig455_014312

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.224

PHYHD1 2.43 - - 0.733 0.709 - 0.988 Mlig455_014312 {REF} {Length: 528} {Pfam: Phytanoyl-CoA dioxygenase (PhyH) [PF05721.15, score=179.8]} {Human: ENSG00000175287, PHYHD1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=237, Expect=1e-76]} {Mouse: ENSMUSG00000079484, Phyhd1, phytanoyl-CoA dioxygenase domain containing 1, [RH, Score=229, Expect=1e-73]} {Dmel: FBgn0037819, CG14688, [RH, Score=206, Expect=4e-65]} {Celegans: WBGene00013650, Y105C5B.9, Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog, [RH, Score=217, Expect=3e-69]} {Smed: dd_Smed_v6_8029_0_1, dd_Smed_v6_8029_0_1, [RH, Score=247, Expect=5e-81]} {RNA1509_42101} {RNA1310_40002} {RNA815_12227}
83. MligTC455_21639 227 4.73 Mlig455_052612

Neo: -

Age: Down-Up-Down

SLC6A5 2.411 - - - 0.703 0.720 0.988 Mlig455_052612 {REF} {Length: 1918} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=351.9]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=311, Expect=6e-98]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=311, Expect=6e-98]} {Dmel: FBgn0034911, CG5549, [Score=307, Expect=5e-94]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=224, Expect=4e-67]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=271, Expect=6e-84]} {RNA1509_26562} {RNA1310_7302.1} {RNA815_18232}
84. MligTC455_21232 518 10.79 Mlig455_003729, Mlig455_003893

Neo: -

Age: -

RP1 2.41 - - 0.732 0.722 - 0.956

Mlig455_003729 {REF} {Length: 9766} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=241.2]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=465, Expect=2e-138]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=433, Expect=2e-125]} {Dmel: FBgn0035229, pns, pinstripe, [Score=61.2, Expect=1e-08]} {Smed: dd_Smed_v6_10315_0_1, dd_Smed_v6_10315_0_1, [Score=583, Expect=6e-178]} {RNA1509_11896, RNA1509_36099, RNA1509_38002, RNA1509_45398} {RNA1310_1638, RNA1509_36099, RNA1509_38002, RNA1509_45398} {RNA1509_36099, RNA1509_38002, RNA1509_45398, RNA815_162}

Mlig455_003893 {REF} {Length: 9769} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=245.2]} {Human: ENSG00000104237, RP1, RP1, axonemal microtubule associated, [Score=469, Expect=1e-139]} {Mouse: ENSMUSG00000025900, Rp1, retinitis pigmentosa 1 (human), [Score=437, Expect=1e-126]} {Dmel: FBgn0035229, pns, pinstripe, [Score=61.2, Expect=1e-08]} {Smed: dd_Smed_v6_10315_0_2, dd_Smed_v6_10315_0_2, [Score=591, Expect=0.0]} {RNA1509_11896, RNA1509_54254} {RNA1310_1638, RNA1509_54254} {RNA1509_54254, RNA815_162}
85. MligTC455_48462 203 4.23 Mlig455_064805

Neo: -

Age: -

TTC39A 2.398 - 0.706 - 0.735 - 0.957 Mlig455_064805 {REF} {Length: 4183} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF3808) [PF10300.11, score=394.5]; Tetratricopeptide repeat [PF07719.19, score=21.4]; Tetratricopeptide repeat [PF13181.8, score=21.4]; Tetratricopeptide repeat [PF00515.30, score=19.8]} {Human: ENSG00000085831, TTC39A, tetratricopeptide repeat domain 39A, [RH, Score=408, Expect=2e-135]; ENSG00000155158, TTC39B, tetratricopeptide repeat domain 39B, [RH, Score=403, Expect=3e-132]} {Mouse: ENSMUSG00000038172, Ttc39b, tetratricopeptide repeat domain 39B, [RH, Score=421, Expect=4e-140]; ENSMUSG00000028555, Ttc39a, tetratricopeptide repeat domain 39A, [RH, Score=418, Expect=1e-139]} {Celegans: WBGene00016314, C32D5.6, [RH, Score=346, Expect=5e-112]} {Smed: dd_Smed_v6_6902_0_1, dd_Smed_v6_6902_0_1, [RH, Score=454, Expect=3e-153]} {RNA1509_8690} {RNA1310_11081.1} {RNA815_1950.1}
86. MligTC455_22804 350 7.3 Mlig455_067193

Neo: -

Age: logFC(26M/2M)=-0.439

Region-enriched R2: 2.883/0.00412

TEKT3 2.395 0.704 - - 0.734 - 0.957 Mlig455_067193 {REF} {Length: 4067} {Pfam: Tektin family [PF03148.16, score=437.3]; fzo-like conserved region [PF04799.15, score=18.2]} {Human: ENSG00000125409, TEKT3, tektin 3, [Score=358, Expect=6e-119]} {Mouse: ENSMUSG00000042189, Tekt3, tektin 3, [Score=342, Expect=6e-113]} {Dmel: FBgn0052820, CG32820, [Score=286, Expect=5e-91]} {Smed: dd_Smed_v6_6511_0_1, dd_Smed_v6_6511_0_1, [RH, Score=552, Expect=0.0]} {RNA1509_7137} {RNA1310_13532} {RNA815_5924}
87. MligTC455_22569 338 7.03 Mlig455_006660

Neo: -

Age: -

2.389 - - 0.729 0.710 0.950 - Mlig455_006660 {REF} {Length: 4485} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=28.7]; Ankyrin repeats (3 copies) [PF12796.9, score=26.1]; Ankyrin repeats (many copies) [PF13857.8, score=22.7]; Ankyrin repeat [PF13606.8, score=20.1]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=50.1, Expect=6e-06]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=48.9, Expect=6e-06]} {RNA1509_12214} {RNA1310_987} {RNA815_3324}
88. MligTC455_23171 303 6.31 Mlig455_004997

Neo: -

Age: Up-Down-Down

GRIA2 2.385 - - - 0.725 0.704 0.956 Mlig455_004997 {REF} {Length: 2499} {TRANSSPLICED} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=89.2]; Ligand-gated ion channel [PF00060.28, score=67.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=55.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=135, Expect=3e-35]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=134, Expect=7e-35]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=130, Expect=1e-33]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=135, Expect=2e-35]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=134, Expect=5e-35]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=130, Expect=8e-34]} {Dmel: FBgn0031634, Ir25a, Ionotropic receptor 25a, [Score=110, Expect=5e-27]} {Celegans: WBGene00001617, glr-6, GLutamate Receptor family (AMPA), [Score=106, Expect=1e-25]} {Smed: dd_Smed_v6_7562_0_1, dd_Smed_v6_7562_0_1, [Score=129, Expect=1e-33]} {RNA1509_11251} {RNA1310_13034} {RNA815_2128.1}
89. MligTC455_30223 110 2.29 Mlig455_025799

Neo: -

Age: Down-Down-Down

PIF1 1.966 - - - - 0.977 0.989 Mlig455_025799 {REF} {Length: 9227} {Pfam: PIF1-like helicase [PF05970.16, score=333.7]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.7]; AAA domain [PF13604.8, score=45.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.5]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=2e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=122, Expect=5e-28]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=116, Expect=4e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
90. MligTC455_46163 276 5.75 Mlig455_038039

Neo: -

Age: Down-Up-Up

MAP3K19 1.957 - - - 0.965 - 0.992 Mlig455_038039 {REF} {Length: 2880} {Pfam: Protein kinase domain [PF00069.27, score=170.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.8]; Ankyrin repeats (3 copies) [PF12796.9, score=87.0]; Ankyrin repeats (many copies) [PF13857.8, score=62.7]; Ankyrin repeats (many copies) [PF13637.8, score=54.2]; Ankyrin repeat [PF13606.8, score=43.2]; Ankyrin repeat [PF00023.32, score=39.4]; Fungal protein kinase [PF17667.3, score=25.5]; ABC1 atypical kinase-like domain [PF03109.18, score=21.0]; Phosphotransferase enzyme family [PF01636.25, score=20.9]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=144, Expect=6e-36]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=147, Expect=2e-37]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=5e-29]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=113, Expect=1e-25]} {Smed: dd_Smed_v6_8526_0_8, dd_Smed_v6_8526_0_8, [Score=110, Expect=2e-25]} {RNA1509_28974} {RNA1310_12914, RNA1509_28974} {RNA1509_28974, RNA815_9717}
91. MligTC455_41151 536 11.16 Mlig455_007760

Neo: -

Age: -

PNKP 1.947 - - - - 0.974 0.973 Mlig455_007760 {REF} {Length: 1965} {TRANSSPLICED} {Pfam: Polynucleotide kinase 3 phosphatase [PF08645.13, score=165.7]; AAA domain [PF13671.8, score=55.5]; Zeta toxin [PF06414.14, score=20.7]} {Human: ENSG00000039650, PNKP, polynucleotide kinase 3'-phosphatase, [Score=259, Expect=8e-81]} {Mouse: ENSMUSG00000002963, Pnkp, polynucleotide kinase 3'- phosphatase, [Score=244, Expect=4e-75]} {Dmel: FBgn0037578, CG9601, [Score=231, Expect=2e-70]} {Celegans: WBGene00009010, F21D5.5, [Score=254, Expect=2e-80]} {Smed: dd_Smed_v6_1211_0_2, dd_Smed_v6_1211_0_2, [Score=216, Expect=2e-65]} {RNA1509_19728, RNA1509_46985} {RNA1310_14048, RNA1509_19728, RNA1509_46985} {RNA1509_19728, RNA1509_46985, RNA815_7193.1}
92. MligTC455_36910 84 1.75 Mlig455_031683

Neo: -

Age: -

1.923 - - - - 0.931 0.992 Mlig455_031683 {REF} {Length: 4716} {RNA1509_36080} {RNA1310_44068, RNA1509_36080} {RNA1509_36080, RNA815_39601}
93. MligTC455_19429 537 11.18 Mlig455_016019

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.664

Region-enriched R2: 1.983/0.00165

WDR49 1.922 - - 0.970 - 0.952 - Mlig455_016019 {REF} {Length: 4260} {Pfam: WD domain, G-beta repeat [PF00400.34, score=59.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.3]; EF-hand domain pair [PF13833.8, score=22.2]; EF-hand domain pair [PF13499.8, score=20.7]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=310, Expect=1e-88]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=232, Expect=7e-64]; ENSMUSG00000029658, Wdr95, WD40 repeat domain 95, [Score=231, Expect=4e-63]; ENSMUSG00000044083, Efcab8, EF-hand calcium binding domain 8, [Score=226, Expect=9e-60]} {Dmel: FBgn0267449, WDY, WD40 Y, [Score=180, Expect=9e-46]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=306, Expect=3e-87]} {RNA1509_3708} {RNA1310_2384.2, RNA1509_3708} {RNA1509_3708, RNA815_724.1}
94. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

WDR49 1.922 - - 0.966 - 0.956 - Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
95. MligTC455_45196 415 8.66 Mlig455_012327

Neo: -

Age: logFC(26M/2M)=-0.373

INVS 1.915 - - 0.961 - 0.954 - Mlig455_012327 {REF} {Length: 3620} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=130.7]; Ankyrin repeats (many copies) [PF13637.8, score=103.5]; Ankyrin repeats (many copies) [PF13857.8, score=90.3]; Ankyrin repeat [PF13606.8, score=74.3]; Ankyrin repeat [PF00023.32, score=60.1]} {Human: ENSG00000119509, INVS, inversin, [Score=114, Expect=3e-25]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=111, Expect=9e-25]; ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=110, Expect=6e-24]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=107, Expect=3e-23]; ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=107, Expect=2e-23]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=104, Expect=4e-22]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=103, Expect=5e-22]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=102, Expect=2e-21]} {Dmel: FBgn0260487, CG42534, [Score=112, Expect=6e-25]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=115, Expect=3e-26]} {RNA1509_13535, RNA1509_36786} {RNA1310_5307.1, RNA1509_36786} {RNA1509_36786, RNA815_942}
96. MligTC455_23081 239 4.97 Mlig455_070003

Neo: -

Age: logFC(26M/2M)=-0.477

LRP1B 1.911 - - - 0.914 - 0.997 Mlig455_070003 {REF} {Length: 1873} {Pfam: EGF-like domain [PF00008.29, score=35.2]; EGF-like domain [PF07974.15, score=19.2]} {Human: ENSG00000168702, LRP1B, LDL receptor related protein 1B, [Score=58.9, Expect=2e-09]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000027878, Notch2, notch 2, [Score=53.5, Expect=1e-07]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=53.1, Expect=1e-07]} {Dmel: FBgn0004647, N, Notch, [Score=47.8, Expect=5e-06]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=54.3, Expect=3e-08]} {RNA1509_38266} {RNA1310_19274, RNA1509_38266} {RNA1509_38266, RNA815_9585.2}
97. MligTC455_39265 459 9.57 Mlig455_025157, Mlig455_063935

Neo: -

Age: Down-Up-Down

PRX 1.907 - - 0.915 - - 0.992

Mlig455_025157 {REF} {Length: 1721} {RNA1509_50938} {RNA1310_45103} {RNA815_28196.1}

Mlig455_063935 {REF} {Length: 4827} {Human: ENSG00000105227, PRX, periaxin, [Score=66.6, Expect=3e-10]} {RNA1509_50938} {RNA1310_7875} {RNA815_14212}
98. MligTC455_53472 864 17.99 Mlig455_062449

Neo: -

Age: logFC(26M/2M)=-0.311

CFAP65 1.9 - - - - 0.950 0.950 Mlig455_062449 {REF} {Length: 5820} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=92.3]; MSP (Major sperm protein) domain [PF00635.28, score=45.2]; Transmembrane protein 131-like N-terminal [PF12371.10, score=24.9]; Protein of unknown function (DUF1573) [PF07610.13, score=23.0]} {Human: ENSG00000181378, CFAP65, cilia and flagella associated protein 65, [RH, Score=850, Expect=0.0]} {Mouse: ENSMUSG00000047021, Cfap65, cilia and flagella associated protein 65, [RH, Score=842, Expect=0.0]} {Smed: dd_Smed_v6_12428_0_1, dd_Smed_v6_12428_0_1, [RH, Score=1277, Expect=0.0]} {RNA1509_19700, RNA1509_38302, RNA1509_57456} {RNA1310_760, RNA1509_38302, RNA1509_57456} {RNA1509_38302, RNA1509_57456, RNA815_222.1}
99. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 1.896 - - - 0.953 0.943 - Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
100. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

CEP164 1.891 - - 0.924 - 0.967 -

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

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