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Results for MligTC455_53960

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53960 381 7.93 Mlig455_039523

Neo: -

Age: logFC(26M/2M)=-0.527

Region-enriched R2: 1.863/0.02753

 TTLL7 Mlig455_039523 {REF} {Length: 2811} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=44.5]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=146, Expect=5e-37]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=261, Expect=2e-76]} {Dmel: FBgn0039501, CG5987, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=118, Expect=1e-27]} {RNA1509_8901} {RNA1310_4651} {RNA815_1757}

Cumulative graph for MligTC455_53960

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.673 3.304 0.16991 0.79501
RegionR2 1.863 3.304 0.00140 0.02753
RegionR3 0.345 3.304 0.50451 0.99621
RegionR4 0.138 3.304 0.80830 1.00000
RegionR5 -0.132 3.304 0.81517 1.00000
RegionR6 0.598 3.304 0.25193 0.83795
RegionR7 -0.396 3.304 0.62393 1.00000
RegionR8 0.256 3.304 0.75864 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.218 3.304 0.39914 1.00000
RegenerationR2 0.195 3.304 0.60004 0.91549
RegenerationR3 0.118 3.304 0.81258 0.98567
RegenerationR4 -0.518 3.304 0.31552 0.75488
RegenerationR5 -0.563 3.304 0.25227 0.68540
RegenerationR6 -0.857 3.304 0.11585 0.41920
RegenerationBL 0.343 3.304 0.59860 0.94632
RegenerationTP -0.442 3.304 0.59139 0.95574


Genes with expression patterns similar to MligTC455_53960

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53960 381 7.93 Mlig455_039523

Neo: -

Age: logFC(26M/2M)=-0.527

Region-enriched R2: 1.863/0.02753

 TTLL7 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_039523 {REF} {Length: 2811} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=44.5]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=146, Expect=5e-37]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=261, Expect=2e-76]} {Dmel: FBgn0039501, CG5987, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=118, Expect=1e-27]} {RNA1509_8901} {RNA1310_4651} {RNA815_1757}
2. MligTC455_53961 290 6.04 Mlig455_051313

Neo: -

Age: logFC(26M/2M)=-0.591

Region-enriched R2: 2.488/0.02898

 TTLL7 5.646 0.921 0.897 0.959 0.922 0.993 0.954 Mlig455_051313 {REF} {Length: 3404} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=247.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.8]; YheC/D like ATP-grasp [PF14398.8, score=18.8]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [RH, Score=478, Expect=1e-157]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [RH, Score=474, Expect=2e-153]} {Dmel: FBgn0039501, CG5987, [Score=289, Expect=2e-85]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=184, Expect=5e-49]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [RH, Score=408, Expect=4e-128]} {RNA1509_8901} {RNA1310_4651, RNA1509_8901} {RNA1509_8901, RNA815_1757}
3. MligTC455_42082 3720 77.49 Mlig455_018683, Mlig455_043429, Mlig455_043577

Neo: -

Age: -

 4.279 - 0.751 0.852 0.961 0.932 0.783

Mlig455_018683 {REF} {Length: 1408} {Pfam: TRAF-type zinc finger [PF02176.20, score=24.3]} {RNA1509_22344} {RNA1310_27253} {RNA815_10437.1}

Mlig455_043429 {REF} {Length: 2590} {Pfam: TRAF-type zinc finger [PF02176.20, score=31.3]} {RNA1509_17243} {RNA1310_42365.1} {RNA815_10437.2}

Mlig455_043577 {REF} {Length: 1649} {Pfam: TRAF-type zinc finger [PF02176.20, score=24.6]} {RNA1509_17243} {RNA1310_41015} {RNA815_10437.1}
4. MligTC455_08757 509 10.61 Mlig455_010905

Neo: -

Age: -

 4.199 0.805 - 0.769 0.970 0.808 0.847 Mlig455_010905 {REF} {Length: 1700} {TRANSSPLICED} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=62.8, Expect=1e-12]} {RNA1509_51881} {RNA1310_201.1} {RNA815_6427.2}
5. MligTC455_43002 147 3.07 Mlig455_004304

Neo: -

Age: Up-Down-Down

 GLUD1 4.064 0.717 - 0.765 0.756 0.839 0.987 Mlig455_004304 {REF} {Length: 2088} {Pfam: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=134.8]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=288, Expect=8e-94]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=285, Expect=5e-93]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=288, Expect=5e-94]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=288, Expect=2e-96]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=240, Expect=4e-76]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=277, Expect=1e-90]} {RNA1509_18938, RNA1509_30743} {RNA1310_2661.2, RNA1509_18938} {RNA1509_18938, RNA815_713.2}
6. MligTC455_43683 520 10.83 Mlig455_029440

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.407

 3.709 - - 0.903 0.874 0.977 0.955 Mlig455_029440 {REF} {Length: 1842} {RNA1509_21217} {RNA1310_16933.1, RNA1509_21217} {RNA1509_21217, RNA815_7959}
7. MligTC455_44144 1917 39.94 Mlig455_013403

Neo: -

Age: logFC(26M/2M)=-0.387

 TNKS 3.631 - - 0.952 0.896 0.850 0.933 Mlig455_013403 {REF} {Length: 3109} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=73.2]; Ankyrin repeats (many copies) [PF13857.8, score=57.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.5]; Ion transport protein [PF00520.33, score=51.4]; Ankyrin repeat [PF00023.32, score=50.9]; Ankyrin repeat [PF13606.8, score=46.3]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=88.6, Expect=3e-17]; ENSG00000285372, AC270292.3, tankyrase, [Score=87.4, Expect=7e-17]; ENSG00000107854, TNKS2, tankyrase 2, [Score=84.3, Expect=6e-16]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=87.4, Expect=4e-17]; ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=84.0, Expect=5e-16]} {Dmel: FBgn0004647, N, Notch, [Score=80.1, Expect=7e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=82.8, Expect=6e-16]} {Smed: dd_Smed_v6_8547_0_1, dd_Smed_v6_8547_0_1, [Score=79.3, Expect=6e-15]} {RNA1509_2994} {RNA1310_1688.1, RNA1509_2994} {RNA1509_2994, RNA815_1415.1}
8. MligTC455_44145 1616 33.67 Mlig455_013447

Neo: -

Age: -

 3.609 - - 0.944 0.934 0.776 0.955 Mlig455_013447 {REF} {Length: 841} {RNA1509_20243} {RNA1310_1688.1} {RNA815_1415.1}
9. MligTC455_49514 319 6.65 Mlig455_044307

Neo: -

Age: -

 AGBL2 3.604 - - 0.954 0.888 0.843 0.919 Mlig455_044307 {REF} {Length: 4376} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=73.3]; Zinc carboxypeptidase [PF00246.26, score=65.6]} {Human: ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [Score=560, Expect=0.0]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [Score=560, Expect=0.0]; ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [Score=535, Expect=7e-173]} {Mouse: ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [Score=556, Expect=0.0]; ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [Score=540, Expect=8e-174]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=538, Expect=1e-176]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=267, Expect=3e-74]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [Score=585, Expect=0.0]} {RNA1509_10895} {RNA1310_1654.2} {RNA815_1445.1}
10. MligTC455_47923 9994 208.21 Mlig455_031159, Mlig455_031167

Neo: -

Age: logFC(26M/2M)=-0.423

 CCDC63 3.54 0.801 - 0.875 0.957 0.907 -

Mlig455_031159 {REF} {Length: 2325} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=22.9]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [Score=181, Expect=9e-50]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [Score=163, Expect=3e-43]; ENSMUSG00000040189, Ccdc114, coiled-coil domain containing 114, [Score=158, Expect=3e-41]} {Dmel: FBgn0038452, CG14905, [Score=159, Expect=9e-43]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [Score=431, Expect=8e-146]} {RNA1509_2578, RNA1509_9264} {RNA1310_10129.1, RNA1509_2578, RNA1509_9264} {RNA1509_2578, RNA1509_9264, RNA815_3341.1}

Mlig455_031167 {REF} {Length: 2293} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=22.9]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [Score=181, Expect=9e-50]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [Score=163, Expect=3e-43]; ENSMUSG00000040189, Ccdc114, coiled-coil domain containing 114, [Score=158, Expect=3e-41]} {Dmel: FBgn0038452, CG14905, [Score=159, Expect=9e-43]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [Score=431, Expect=8e-146]} {RNA1509_1172, RNA1509_13163, RNA1509_16375, RNA1509_2578} {RNA1310_10129.1, RNA1509_1172, RNA1509_13163, RNA1509_16375} {RNA1509_1172, RNA1509_13163, RNA1509_16375, RNA815_3341.1}
11. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

 PTBP1 3.526 0.723 - 0.955 0.894 0.954 - Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
12. MligTC455_26585 173 3.61 Mlig455_061024

Neo: -

Age: -

 3.501 0.833 - 0.959 0.848 0.861 - Mlig455_061024 {REF} {Length: 2825} {RNA1509_19437} {RNA1310_38787} {RNA815_16416}
13. MligTC455_34893 231 4.8 Mlig455_066819

Neo: -

Age: Down-Up-Down

 CYP2U1 3.481 - 0.746 0.964 0.936 0.835 - Mlig455_066819 {REF} {Length: 1584} {Pfam: Cytochrome P450 [PF00067.24, score=109.5]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=95.5, Expect=9e-24]; ENSG00000186104, CYP2R1, cytochrome P450 family 2 subfamily R member 1, [Score=92.4, Expect=3e-22]; ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=91.3, Expect=9e-22]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=91.3, Expect=6e-22]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=90.5, Expect=1e-21]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=90.5, Expect=1e-21]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=90.1, Expect=1e-21]; ENSMUSG00000030670, Cyp2r1, cytochrome P450, family 2, subfamily r, polypeptide 1, [Score=89.7, Expect=4e-22]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=89.0, Expect=3e-21]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=87.8, Expect=1e-20]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [Score=87.4, Expect=1e-20]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=76.3, Expect=9e-17]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=89.0, Expect=2e-21]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [Score=102, Expect=4e-26]} {RNA1509_39728} {RNA1310_10949.2} {RNA815_7611}
14. MligTC455_34792 238 4.96 Mlig455_045574

Neo: -

Age: logFC(26M/2M)=-0.239

 3.447 - - 0.988 0.727 0.809 0.923 Mlig455_045574 {REF} {Length: 4478} {Smed: dd_Smed_v6_27312_0_1, dd_Smed_v6_27312_0_1, [RH, Score=160, Expect=9e-40]} {RNA1509_6675} {RNA1310_2307, RNA1509_6675} {RNA1509_6675, RNA815_650}
15. MligTC455_48101 874 18.2 Mlig455_018395, Mlig455_069529

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.420/0.02237

 LRRC71 3.444 - 0.726 0.913 0.836 - 0.969

Mlig455_018395 {REF} {Length: 2255} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=67.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=25.6]; Leucine Rich Repeat [PF00560.35, score=24.4]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=199, Expect=3e-56]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=195, Expect=4e-55]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=230, Expect=1e-69]} {RNA1509_18089} {RNA1310_2341.2} {RNA815_677.1}

Mlig455_069529 {REF} {Length: 2441} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=66.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=25.2]; Leucine Rich Repeat [PF00560.35, score=24.2]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=202, Expect=2e-57]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=198, Expect=4e-56]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=227, Expect=2e-68]} {RNA1509_18089} {RNA1310_2341.2, RNA1509_18089} {RNA1509_18089, RNA815_677.1}
16. MligTC455_54217 941 19.61 Mlig455_013990

Neo: -

Age: logFC(26M/2M)=-0.425

 3.44 0.756 - 0.851 0.877 0.956 - Mlig455_013990 {REF} {Length: 3670} {RNA1509_11789} {RNA1310_16926.2, RNA1509_11789} {RNA1509_11789, RNA815_9044}
17. MligTC455_21640 262 5.46 Mlig455_052657

Neo: -

Age: -

 SLC6A5 3.419 0.734 - - 0.861 0.848 0.976 Mlig455_052657 {REF} {Length: 4833} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=583.6]; BTB/POZ domain [PF00651.33, score=59.5]; BTB And C-terminal Kelch [PF07707.17, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=316, Expect=2e-92]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=315, Expect=5e-92]} {Dmel: FBgn0034911, CG5549, [Score=313, Expect=5e-89]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=228, Expect=2e-63]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=273, Expect=1e-78]} {RNA1509_27437} {RNA1310_7302.1} {RNA815_3821}
18. MligTC455_54156 465 9.68 Mlig455_035955

Neo: -

Age: logFC(26M/2M)=-0.401

 PPP1R36 3.416 0.776 - - 0.778 0.911 0.951 Mlig455_035955 {REF} {Length: 2382} {Pfam: Protein phosphatase 1 inhibitor [PF14895.8, score=139.0]} {Human: ENSG00000165807, PPP1R36, protein phosphatase 1 regulatory subunit 36, [RH, Score=191, Expect=1e-55]} {Mouse: ENSMUSG00000052221, Ppp1r36, protein phosphatase 1, regulatory subunit 36, [RH, Score=167, Expect=5e-47]} {RNA1509_6292} {RNA1310_2911.1, RNA1509_6292} {RNA1509_6292, RNA815_5971.1}
19. MligTC455_31847 661 13.78 Mlig455_025501, Mlig455_070503

Neo: -

Age: Down-Up-Down

 KCNMA1 3.395 0.813 - - 0.846 0.765 0.971

Mlig455_025501 {REF} {Length: 4552} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1} {RNA815_830}

Mlig455_070503 {REF} {Length: 4866} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=85.2]; Ion channel [PF07885.18, score=43.4]; Ion transport protein [PF00520.33, score=34.6]; TrkA-N domain [PF02254.20, score=22.5]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=488, Expect=4e-154]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=335, Expect=3e-97]} {Dmel: FBgn0003429, slo, slowpoke, [Score=484, Expect=1e-151]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=454, Expect=9e-141]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=476, Expect=1e-149]} {RNA1509_14763} {RNA1310_2844.1, RNA1509_14763} {RNA1509_14763, RNA815_830}
20. MligTC455_39504 298 6.2 Mlig455_017354

Neo: -

Age: -

Region-enriched R2: 2.428/0.04005

 DTHD1 3.376 0.772 - 0.845 0.951 0.808 - Mlig455_017354 {REF} {Length: 3800} {Pfam: Death domain [PF00531.24, score=30.4]} {Human: ENSG00000197057, DTHD1, death domain containing 1, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000090326, Dthd1, death domain containing 1, [RH, Score=105, Expect=8e-23]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [RH, Score=169, Expect=3e-43]} {RNA1509_9917} {RNA1310_4320.1} {RNA815_4192.1}
21. MligTC455_50914 714 14.87 Mlig455_005873

Neo: -

Age: -

Region-enriched R2: 2.125/0.01399

 DNHD1 3.349 0.717 - 0.967 0.873 0.792 - Mlig455_005873 {REF} {Length: 14506} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=207.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=114.3]; P-loop containing dynein motor region D4 [PF12780.9, score=60.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=54.5]; P-loop containing dynein motor region [PF12775.9, score=46.5]; Dynein heavy chain C-terminal domain [PF18199.3, score=42.8]; Dynein heavy chain AAA lid domain [PF17852.3, score=38.9]; AAA domain [PF13401.8, score=22.7]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=20.3]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=19.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=159, Expect=1e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=177, Expect=3e-43]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=4e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=82.0, Expect=1e-14]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [Score=331, Expect=5e-90]} {RNA1509_32900} {RNA1310_31} {RNA815_1203}
22. MligTC455_22285 679 14.14 Mlig455_019090, Mlig455_064274

Neo: -

Age: -

Region-enriched R2: 1.663/0.01632

 INVS 3.332 0.796 - - 0.811 0.771 0.954

Mlig455_019090 {REF} {Length: 5312} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=202.1]; Ankyrin repeats (many copies) [PF13637.8, score=171.0]; Ankyrin repeat [PF00023.32, score=132.7]; Ankyrin repeat [PF13606.8, score=120.3]; Ankyrin repeats (many copies) [PF13857.8, score=107.4]} {Human: ENSG00000119509, INVS, inversin, [Score=155, Expect=1e-37]; ENSG00000151150, ANK3, ankyrin 3, [Score=152, Expect=4e-36]} {Mouse: ENSMUSG00000028344, Invs, inversin, [Score=156, Expect=5e-38]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=152, Expect=3e-36]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=149, Expect=1e-35]} {Dmel: FBgn0260487, CG42534, [RH, Score=293, Expect=1e-80]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [RH, Score=176, Expect=9e-45]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [RH, Score=471, Expect=3e-145]} {RNA1509_45730, RNA1509_6692} {RNA1310_1162.1, RNA1509_45730, RNA1509_6692} {RNA1509_45730, RNA1509_6692, RNA815_2654}

Mlig455_064274 {REF} {Length: 5181} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=202.3]; Ankyrin repeats (many copies) [PF13637.8, score=171.3]; Ankyrin repeat [PF00023.32, score=133.2]; Ankyrin repeat [PF13606.8, score=120.8]; Ankyrin repeats (many copies) [PF13857.8, score=107.9]} {Human: ENSG00000119509, INVS, inversin, [Score=155, Expect=1e-37]; ENSG00000151150, ANK3, ankyrin 3, [Score=151, Expect=6e-36]} {Mouse: ENSMUSG00000028344, Invs, inversin, [Score=156, Expect=6e-38]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=151, Expect=4e-36]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=149, Expect=1e-35]} {Dmel: FBgn0260487, CG42534, [RH, Score=293, Expect=1e-80]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [RH, Score=176, Expect=8e-45]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [RH, Score=471, Expect=2e-145]} {RNA1509_6692} {RNA1310_1162.1} {RNA815_2654}
23. MligTC455_42812 255 5.31 Mlig455_051711

Neo: -

Age: Down-Up-Down

 3.324 - - 0.733 0.723 0.900 0.968 Mlig455_051711 {REF} {Length: 2796} {TRANSSPLICED} {Smed: dd_Smed_v6_11800_0_1, dd_Smed_v6_11800_0_1, [Score=82.0, Expect=8e-16]} {RNA1509_36206} {RNA1310_23933, RNA1509_36206} {RNA1509_36206, RNA815_12504}
24. MligTC455_50505 454 9.46 Mlig455_050904

Neo: -

Age: Down-Up-Up

 3.315 - 0.707 0.738 - 0.893 0.977 Mlig455_050904 {REF} {Length: 1806} {RNA1509_31617} {RNA1310_16888, RNA1509_31617} {RNA1509_31617, RNA815_20985}
25. MligTC455_15661 322 6.72 Mlig455_000589

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.500/0.00231

 NR2E1 3.309 - - 0.954 0.798 0.855 0.702 Mlig455_000589 {REF} {Length: 2434} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=97.6]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=73.9]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [Score=188, Expect=2e-53]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [Score=188, Expect=1e-53]} {Dmel: FBgn0003720, tll, tailless, [RH, Score=202, Expect=2e-58]} {Celegans: WBGene00003657, nhr-67, Nuclear hormone receptor family member nhr-67, [RH, Score=193, Expect=3e-55]} {Smed: dd_Smed_v6_21347_0_1, dd_Smed_v6_21347_0_1, [RH, Score=188, Expect=9e-54]} {RNA1509_39776} {RNA1310_21550, RNA1509_39776} {RNA1509_39776, RNA815_27099.1}
26. MligTC455_41368 369 7.68 Mlig455_007683, Mlig455_020872, Mlig455_020918, Mlig455_020998

Neo: -

Age: -

 3.301 0.701 - 0.817 0.825 0.958 -

Mlig455_007683 {REF} {Length: 1379} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020872 {REF} {Length: 1217} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020918 {REF} {Length: 1220} {RNA1310_25040.2} {RNA815_12562.1}

Mlig455_020998 {REF} {Length: 1235} {RNA1310_25040.1} {RNA815_12562.1}
27. MligTC455_12970 132 2.76 Mlig455_022445

Neo: -

Age: logFC(26M/2M)=-1.642

 3.298 - - 0.730 0.813 0.799 0.956 Mlig455_022445 {REF} {Length: 1567} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=21.7]} {RNA1509_43359} {RNA1310_32360, RNA1509_43359} {RNA1509_43359, RNA815_34556}
28. MligTC455_37572 2798 58.29 Mlig455_009432

Neo: -

Age: logFC(26M/2M)=-0.283

 RIBC2 3.233 0.703 - 0.750 0.966 0.814 - Mlig455_009432 {REF} {Length: 2170} {Pfam: RIB43A [PF05914.14, score=482.0]} {Human: ENSG00000128408, RIBC2, RIB43A domain with coiled-coils 2, [RH, Score=295, Expect=2e-97]} {Mouse: ENSMUSG00000022431, Ribc2, RIB43A domain with coiled-coils 2, [RH, Score=254, Expect=3e-81]} {Dmel: FBgn0036214, CG7264, [RH, Score=136, Expect=2e-36]} {Smed: dd_Smed_v6_26360_0_1, dd_Smed_v6_26360_0_1, [RH, Score=439, Expect=4e-154]} {RNA1509_2052, RNA1509_25329, RNA1509_44631} {RNA1310_13602.1, RNA1509_2052, RNA1509_25329, RNA1509_44631} {RNA1509_2052, RNA1509_25329, RNA1509_44631, RNA815_3363.1}
29. MligTC455_45837 631 13.15 Mlig455_055002

Neo: -

Age: -

 2.833 - - 0.922 0.943 0.968 - Mlig455_055002 {REF} {Length: 821} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
30. MligTC455_42172 67 1.39 Mlig455_066943

Neo: -

Age: Down-Up-Up

 2.805 - - 0.947 0.955 0.903 - Mlig455_066943 {REF} {Length: 2101} {Pfam: Innexin [PF00876.20, score=94.4]} {Celegans: WBGene00002133, inx-11, Innexin-11, [Score=87.8, Expect=9e-20]} {Smed: dd_Smed_v6_11501_0_1, dd_Smed_v6_11501_0_1, [Score=112, Expect=1e-28]} {RNA1509_10527} {RNA1310_14408} {RNA815_844.2}
31. MligTC455_43616 1798 37.45 Mlig455_024513

Neo: -

Age: logFC(26M/2M)=-0.338

Region-enriched R2: 1.066/0.02738

 CFAP57 2.791 - - 0.898 0.951 0.942 - Mlig455_024513 {REF} {Length: 5805} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=65.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=24.0]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=20.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=496, Expect=5e-155]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1620, Expect=0.0]} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA1509_836} {RNA1310_1737, RNA1509_14259, RNA1509_18569, RNA1509_42897} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA815_558}
32. MligTC455_51696 624 12.99 Mlig455_011356

Neo: -

Age: -

 FAM47E 2.779 - - 0.953 0.926 0.900 - Mlig455_011356 {REF} {Length: 2028} {Pfam: FAM47 family [PF14642.8, score=51.3]} {Human: ENSG00000189157, FAM47E, family with sequence similarity 47 member E, [RH, Score=138, Expect=9e-36]} {Mouse: ENSMUSG00000078315, Fam47c, family with sequence similarity 47, member C, [RH, Score=119, Expect=6e-29]} {Smed: dd_Smed_v6_10346_0_1, dd_Smed_v6_10346_0_1, [RH, Score=293, Expect=6e-95]} {RNA1509_41096, RNA1509_54260, RNA1509_8031} {RNA1310_12665, RNA1509_41096, RNA1509_54260} {RNA1509_41096, RNA1509_54260, RNA815_4489.1}
33. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

 SYTL4 2.76 - - 0.889 0.898 0.973 - Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
34. MligTC455_40657 90 1.87 Mlig455_040779

Neo: -

Age: -

 CLIP2 2.735 - - 0.925 0.848 0.962 - Mlig455_040779 {REF} {Length: 2164} {Pfam: CAP-Gly domain [PF01302.27, score=60.7]} {Human: ENSG00000106665, CLIP2, CAP-Gly domain containing linker protein 2, [Score=61.6, Expect=2e-09]} {Mouse: ENSMUSG00000063146, Clip2, CAP-GLY domain containing linker protein 2, [Score=62.0, Expect=1e-09]} {Dmel: FBgn0036882, CG9279, [Score=54.7, Expect=1e-07]} {Smed: dd_Smed_v6_12985_0_1, dd_Smed_v6_12985_0_1, [Score=56.2, Expect=2e-08]} {RNA1310_20676} {RNA815_40746}
35. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

 KY 2.716 - - 0.926 0.840 0.950 -

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
36. MligTC455_17580 2178 45.37 Mlig455_048028

Neo: -

Age: Down-Up-Up

 2.71 - - - 0.874 0.857 0.979 Mlig455_048028 {REF} {Length: 5222} {RNA1509_12558, RNA1509_43882} {RNA1310_10969, RNA1509_43882} {RNA1509_43882, RNA815_3485.1}
37. MligTC455_43972 1061 22.11 Mlig455_047704

Neo: -

Age: -

 2.697 - - 0.774 0.953 0.970 - Mlig455_047704 {REF} {Length: 2155} {TRANSSPLICED} {RNA1509_7618} {RNA1310_9007} {RNA815_27926.1}
38. MligTC455_50915 531 11.06 Mlig455_028745

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.109/0.02468

 DNHD1 2.688 - - 0.973 0.879 0.836 - Mlig455_028745 {REF} {Length: 14999} {TRANSSPLICED} {Pfam: Dynein heavy chain, N-terminal region 2 [PF08393.15, score=214.3]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=113.4]; P-loop containing dynein motor region D4 [PF12780.9, score=60.1]; Microtubule-binding stalk of dynein motor [PF12777.9, score=55.6]; P-loop containing dynein motor region [PF12775.9, score=49.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=44.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=40.5]; AAA domain [PF13401.8, score=23.5]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=22.3]; Dynein heavy chain AAA lid domain [PF18198.3, score=22.0]; Protein of unknown function (DUF815) [PF05673.15, score=21.1]; AAA domain [PF13604.8, score=18.7]} {Human: ENSG00000179532, DNHD1, dynein heavy chain domain 1, [Score=157, Expect=4e-37]} {Mouse: ENSMUSG00000030882, Dnhd1, dynein heavy chain domain 1, [Score=249, Expect=8e-65]} {Dmel: FBgn0013811, Dhc62B, Dynein heavy chain at 62B, [Score=114, Expect=2e-24]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=84.0, Expect=4e-15]} {Smed: dd_Smed_v6_8984_0_1, dd_Smed_v6_8984_0_1, [RH, Score=443, Expect=5e-124]} {RNA1509_1896} {RNA1310_31, RNA1509_1896} {RNA1509_1896, RNA815_1203}
39. MligTC455_43110 746 15.54 Mlig455_029622

Neo: -

Age: -

Region-enriched R2: 1.632/0.03045

 ARRDC2 2.683 - - - 0.889 0.839 0.955 Mlig455_029622 {REF} {Length: 1778} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=52.7]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=39.2]} {Human: ENSG00000105643, ARRDC2, arrestin domain containing 2, [Score=76.6, Expect=5e-15]} {Mouse: ENSMUSG00000110906, Arrdc2, arrestin domain containing 2, [Score=84.7, Expect=7e-18]; ENSMUSG00000002910, Arrdc2, arrestin domain containing 2, [Score=84.7, Expect=7e-18]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=76.3, Expect=2e-15]} {Celegans: WBGene00011732, arrd-17, Arrestin domain-containing protein 17, [Score=60.5, Expect=4e-10]} {Smed: dd_Smed_v6_8715_0_1, dd_Smed_v6_8715_0_1, [Score=51.6, Expect=3e-07]} {RNA1509_45476} {RNA1310_16251} {RNA815_9075}
40. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

 NKX2-1, NKX2-4 2.682 - - 0.914 0.811 0.957 -

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
41. MligTC455_38148 787 16.4 Mlig455_067155

Neo: -

Age: -

 FAT1 2.679 - - 0.881 0.835 0.963 - Mlig455_067155 {REF} {Length: 4823} {Pfam: Cadherin domain [PF00028.19, score=183.7]; EGF-like domain [PF00008.29, score=55.8]; Calcium-binding EGF domain [PF07645.17, score=31.4]; Laminin G domain [PF02210.26, score=24.7]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=292, Expect=3e-79]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=299, Expect=2e-81]} {Dmel: FBgn0261574, kug, kugelei, [Score=213, Expect=3e-55]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=189, Expect=9e-48]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=218, Expect=1e-56]} {RNA1509_13557} {RNA1310_1912.1} {RNA815_14235}
42. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

 WDR49 2.678 - - 0.954 0.773 0.951 - Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
43. MligTC455_27689 21816 454.5 Mlig455_035623

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.278

 TUBA1A 2.676 - - 0.951 0.893 0.832 - Mlig455_035623 {REF} {Length: 2313} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=213.7]; Tubulin C-terminal domain [PF03953.19, score=176.0]; Tubulin domain [PF14881.8, score=19.3]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [Score=854, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [Score=853, Expect=0.0]; ENSG00000075886, TUBA3D, tubulin alpha 3d, [Score=845, Expect=0.0]; ENSG00000198033, TUBA3C, tubulin alpha 3c, [Score=845, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [Score=854, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [Score=853, Expect=0.0]; ENSMUSG00000067338, Tuba3b, tubulin, alpha 3B, [Score=845, Expect=0.0]; ENSMUSG00000067702, Tuba3a, tubulin, alpha 3A, [Score=845, Expect=0.0]} {Dmel: FBgn0003885, alphaTub84D, alpha-Tubulin at 84D, [Score=837, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [Score=776, Expect=0.0]} {Smed: dd_Smed_v6_10947_0_2, dd_Smed_v6_10947_0_2, [Score=852, Expect=0.0]} {RNA1509_17783} {RNA1310_26095} {RNA815_3971.1}
44. MligTC455_43971 1049 21.85 Mlig455_014401

Neo: -

Age: logFC(26M/2M)=-0.330

 NEK1 2.67 - - 0.744 0.952 0.974 - Mlig455_014401 {REF} {Length: 2439} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=118.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=68.0]; Kinase-like [PF14531.8, score=20.7]} {Human: ENSG00000137601, NEK1, NIMA related kinase 1, [Score=111, Expect=1e-24]} {Mouse: ENSMUSG00000049897, Stkld1, serine/threonine kinase-like domain containing 1, [RH, Score=142, Expect=3e-35]} {Dmel: FBgn0029970, Nek2, [Score=68.9, Expect=8e-12]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=89.4, Expect=3e-18]} {Smed: dd_Smed_v6_10144_0_2, dd_Smed_v6_10144_0_2, [Score=100, Expect=7e-22]} {RNA1509_7618} {RNA1310_9007, RNA1509_7618} {RNA1509_7618, RNA815_6823}
45. MligTC455_44588 393 8.19 Mlig455_029075

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.404

 CASP8 2.667 - - 0.858 0.857 0.952 - Mlig455_029075 {REF} {Length: 2730} {Pfam: Caspase domain [PF00656.24, score=122.9]; Ankyrin repeats (3 copies) [PF12796.9, score=78.1]; Ankyrin repeats (many copies) [PF13637.8, score=65.6]; Ankyrin repeat [PF13606.8, score=61.3]; Ankyrin repeats (many copies) [PF13857.8, score=58.2]; Ankyrin repeat [PF00023.32, score=55.5]} {Human: ENSG00000064012, CASP8, caspase 8, [RH, Score=183, Expect=1e-50]} {Mouse: ENSMUSG00000026029, Casp8, caspase 8, [RH, Score=194, Expect=5e-55]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=149, Expect=4e-40]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=128, Expect=5e-33]} {Smed: dd_Smed_v6_4986_0_1, dd_Smed_v6_4986_0_1, [Score=127, Expect=3e-33]} {RNA1509_39135, RNA1509_56179} {RNA1310_8056, RNA1509_39135, RNA1509_56179} {RNA1509_39135, RNA1509_56179, RNA815_3832.1}
46. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

 CCDC39 2.664 - - 0.802 0.963 0.899 - Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
47. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

 PC 2.658 - - 0.936 0.772 0.950 -

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
48. MligTC455_18347 118 2.46 Mlig455_000821

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.590

 KCNA1 2.649 - - 0.754 - 0.961 0.934 Mlig455_000821 {REF} {Length: 3163} {Pfam: Ion transport protein [PF00520.33, score=166.1]; BTB/POZ domain [PF02214.24, score=97.8]; Ion channel [PF07885.18, score=48.4]} {Human: ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=611, Expect=0.0]; ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=611, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=610, Expect=0.0]; ENSG00000182255, KCNA4, potassium voltage-gated channel subfamily A member 4, [RH, Score=585, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=611, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=610, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]; ENSMUSG00000042604, Kcna4, potassium voltage-gated channel, shaker-related subfamily, member 4, [RH, Score=587, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=629, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=377, Expect=2e-124]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=707, Expect=0.0]} {RNA1509_47579} {RNA1310_8777} {RNA815_4701}
49. MligTC455_38828 995 20.73 Mlig455_009774, Mlig455_054924

Neo: -

Age: Down-Up-Down

Region-enriched R8: 1.773/0.01787
Region-enriched R7: 1.452/0.03515

 CELSR2 2.647 - - 0.934 0.736 0.977 -

Mlig455_009774 {REF} {Length: 2779} {Pfam: Cadherin domain [PF00028.19, score=114.6]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=110, Expect=3e-24]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=107, Expect=3e-23]} {Dmel: FBgn0039294, Cad96Cb, Cadherin 96Cb, [RH, Score=133, Expect=7e-32]} {Celegans: WBGene00000401, cdh-9, CaDHerin family, [RH, Score=79.7, Expect=3e-15]} {Smed: dd_Smed_v6_14410_0_1, dd_Smed_v6_14410_0_1, [Score=77.0, Expect=2e-14]} {RNA1509_6574} {RNA1310_7530, RNA1509_6574} {RNA1509_6574, RNA815_2409}

Mlig455_054924 {REF} {Length: 2736} {Pfam: Cadherin domain [PF00028.19, score=113.4]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=108, Expect=1e-23]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=104, Expect=2e-22]} {Dmel: FBgn0039294, Cad96Cb, Cadherin 96Cb, [RH, Score=130, Expect=5e-31]} {Celegans: WBGene00000401, cdh-9, CaDHerin family, [RH, Score=82.8, Expect=3e-16]} {Smed: dd_Smed_v6_14410_0_1, dd_Smed_v6_14410_0_1, [Score=78.2, Expect=9e-15]} {RNA1509_57757, RNA1509_6574} {RNA1310_7530, RNA1509_57757} {RNA1509_57757, RNA815_2409}
50. MligTC455_24073 886 18.47 Mlig455_022269

Neo: -

Age: logFC(26M/2M)=-0.424

 2.646 - - 0.916 0.964 0.766 - Mlig455_022269 {REF} {Length: 2445} {Smed: dd_Smed_v6_8763_0_1, dd_Smed_v6_8763_0_1, [RH, Score=98.6, Expect=8e-23]} {RNA1509_5814} {RNA1310_13945} {RNA815_5072}
51. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

 CEP164 2.644 0.731 - 0.956 - 0.957 -

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}
52. MligTC455_27988 1036 21.59 Mlig455_006811, Mlig455_055192

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.311

 CFAP54 2.641 - - 0.956 0.886 0.799 -

Mlig455_006811 {REF} {Length: 11171} {Pfam: Cilia- and flagella-associated protein 54 [PF14858.8, score=586.0]} {Human: ENSG00000188596, CFAP54, cilia and flagella associated protein 54, [RH, Score=1136, Expect=0.0]} {Mouse: ENSMUSG00000020014, Cfap54, cilia and flagella associated protein 54, [Score=1144, Expect=0.0]} {Smed: dd_Smed_v6_9860_0_1, dd_Smed_v6_9860_0_1, [Score=347, Expect=2e-95]} {RNA1509_2904} {RNA1310_96.1} {RNA815_135}

Mlig455_055192 {REF} {Length: 10890} {Pfam: Cilia- and flagella-associated protein 54 [PF14858.8, score=578.4]} {Human: ENSG00000188596, CFAP54, cilia and flagella associated protein 54, [Score=1112, Expect=0.0]} {Mouse: ENSMUSG00000020014, Cfap54, cilia and flagella associated protein 54, [RH, Score=1114, Expect=0.0]} {Smed: dd_Smed_v6_9860_0_2, dd_Smed_v6_9860_0_2, [RH, Score=519, Expect=1e-147]} {RNA1509_2904} {RNA1310_96.1} {RNA815_135}
53. MligTC455_42733 190 3.96 Mlig455_060196

Neo: -

Age: logFC(26M/2M)=-0.623

 SLC22A7 2.635 - - 0.964 0.728 0.943 - Mlig455_060196 {REF} {Length: 2722} {Pfam: Sugar (and other) transporter [PF00083.26, score=94.3]; Major Facilitator Superfamily [PF07690.18, score=70.1]} {Human: ENSG00000137204, SLC22A7, solute carrier family 22 member 7, [Score=125, Expect=3e-30]} {Mouse: ENSMUSG00000074028, Slc22a13, solute carrier family 22 (organic cation transporter), member 13, [Score=124, Expect=7e-30]; ENSMUSG00000067144, Slc22a7, solute carrier family 22 (organic anion transporter), member 7, [Score=121, Expect=3e-29]} {Dmel: FBgn0034479, CG8654, [Score=115, Expect=2e-27]} {Celegans: WBGene00019408, K05F1.6, [Score=71.6, Expect=5e-13]} {Smed: dd_Smed_v6_1159_0_1, dd_Smed_v6_1159_0_1, [Score=87.8, Expect=2e-18]} {RNA1509_11814} {RNA1310_15619.1} {RNA815_5783.2}
54. MligTC455_40039 210 4.37 Mlig455_044449

Neo: -

Age: Down-Up-Up

 2.632 - - - 0.843 0.819 0.970 Mlig455_044449 {REF} {Length: 1349} {Pfam: Ets-domain [PF00178.24, score=21.9]} {RNA1509_38421} {RNA1310_33082} {RNA815_26283}
55. MligTC455_45196 415 8.66 Mlig455_012327

Neo: -

Age: logFC(26M/2M)=-0.373

 INVS 2.63 - - 0.927 0.746 0.957 - Mlig455_012327 {REF} {Length: 3620} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=130.7]; Ankyrin repeats (many copies) [PF13637.8, score=103.5]; Ankyrin repeats (many copies) [PF13857.8, score=90.3]; Ankyrin repeat [PF13606.8, score=74.3]; Ankyrin repeat [PF00023.32, score=60.1]} {Human: ENSG00000119509, INVS, inversin, [Score=114, Expect=3e-25]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=111, Expect=9e-25]; ENSG00000139645, ANKRD52, ankyrin repeat domain 52, [Score=110, Expect=6e-24]} {Mouse: ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=107, Expect=3e-23]; ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=107, Expect=2e-23]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=104, Expect=4e-22]; ENSMUSG00000014496, Ankrd28, ankyrin repeat domain 28, [Score=103, Expect=5e-22]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=102, Expect=2e-21]} {Dmel: FBgn0260487, CG42534, [Score=112, Expect=6e-25]} {Celegans: WBGene00021304, nphp-2, NePHronoPhthisis (Human kidney disease) homolog, [Score=99.0, Expect=5e-21]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=115, Expect=3e-26]} {RNA1509_13535, RNA1509_36786} {RNA1310_5307.1, RNA1509_36786} {RNA1509_36786, RNA815_942}
56. MligTC455_53778 951 19.82 Mlig455_007965, Mlig455_015595

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.392

Region-enriched R4: 2.645/0.00192

 PRXL2C 2.628 - - 0.761 0.898 0.969 -

Mlig455_007965 {REF} {Length: 1357} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=24.2]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [Score=108, Expect=6e-30]} {RNA1509_57652} {RNA1310_27001.1} {RNA815_11622}

Mlig455_015595 {REF} {Length: 1838} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=40.9]} {Human: ENSG00000158122, PRXL2C, peroxiredoxin like 2C, [RH, Score=135, Expect=5e-39]} {Mouse: ENSMUSG00000021482, Aaed1, AhpC/TSA antioxidant enzyme domain containing 1, [Score=125, Expect=3e-35]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [RH, Score=149, Expect=3e-45]} {RNA1509_57652} {RNA1310_27001.2, RNA1509_57652} {RNA1509_57652, RNA815_11622}
57. MligTC455_50769 157 3.28 Mlig455_011755, Mlig455_019899, Mlig455_047969

Neo: -

Age: -

 ROR1, ROR2 2.627 0.838 - 0.973 0.816 - -

Mlig455_011755 {REF} {Length: 2365} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=250.7]; Protein kinase domain [PF00069.27, score=106.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=328, Expect=5e-102]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=331, Expect=7e-103]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=1e-93]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=228, Expect=4e-65]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=307, Expect=7e-95]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}

Mlig455_019899 {REF} {Length: 3742} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.8]; Protein kinase domain [PF00069.27, score=103.2]; Immunoglobulin I-set domain [PF07679.18, score=46.1]; Immunoglobulin domain [PF13927.8, score=44.2]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.0]; Kringle domain [PF00051.20, score=23.5]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=393, Expect=1e-120]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=393, Expect=5e-121]} {Dmel: FBgn0010407, Ror, [RH, Score=300, Expect=3e-89]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=291, Expect=4e-84]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=439, Expect=2e-139]} {RNA1509_34377} {RNA1310_12745, RNA1509_34377} {RNA1509_34377, RNA815_11383}

Mlig455_047969 {REF} {Length: 3775} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=248.3]; Protein kinase domain [PF00069.27, score=104.3]; Immunoglobulin I-set domain [PF07679.18, score=46.2]; Immunoglobulin domain [PF13927.8, score=44.1]; Immunoglobulin domain [PF00047.27, score=28.0]; Immunoglobulin domain [PF13895.8, score=27.3]; Fz domain [PF01392.24, score=27.1]; Kringle domain [PF00051.20, score=22.3]} {Human: ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [Score=387, Expect=7e-119]} {Mouse: ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=386, Expect=1e-118]} {Dmel: FBgn0010407, Ror, [RH, Score=297, Expect=4e-88]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=285, Expect=5e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=441, Expect=3e-140]} {RNA1509_34377} {RNA1310_12745} {RNA815_11383}
58. MligTC455_21721 1177 24.51 Mlig455_052943, Mlig455_053013

Neo: -

Age: -

 TRPM3 2.624 0.758 - - 0.914 0.952 -

Mlig455_052943 {REF} {Length: 4423} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.0]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=52.7]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=521, Expect=2e-158]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=522, Expect=1e-158]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=484, Expect=1e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=362, Expect=8e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=607, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1} {RNA815_652.1}

Mlig455_053013 {REF} {Length: 4421} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=222.1]; SLOG in TRPM, prokaryote [PF18171.3, score=68.5]; Ion transport protein [PF00520.33, score=53.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [RH, Score=517, Expect=8e-157]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [RH, Score=519, Expect=2e-157]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=482, Expect=8e-149]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=363, Expect=2e-104]} {Smed: dd_Smed_v6_13119_0_1, dd_Smed_v6_13119_0_1, [Score=605, Expect=0.0]} {RNA1509_4847} {RNA1310_1801.1, RNA1509_4847} {RNA1509_4847, RNA815_652.1}
59. MligTC455_41151 536 11.16 Mlig455_007760

Neo: -

Age: -

 PNKP 2.621 - - - 0.765 0.959 0.897 Mlig455_007760 {REF} {Length: 1965} {TRANSSPLICED} {Pfam: Polynucleotide kinase 3 phosphatase [PF08645.13, score=165.7]; AAA domain [PF13671.8, score=55.5]; Zeta toxin [PF06414.14, score=20.7]} {Human: ENSG00000039650, PNKP, polynucleotide kinase 3'-phosphatase, [Score=259, Expect=8e-81]} {Mouse: ENSMUSG00000002963, Pnkp, polynucleotide kinase 3'- phosphatase, [Score=244, Expect=4e-75]} {Dmel: FBgn0037578, CG9601, [Score=231, Expect=2e-70]} {Celegans: WBGene00009010, F21D5.5, [Score=254, Expect=2e-80]} {Smed: dd_Smed_v6_1211_0_2, dd_Smed_v6_1211_0_2, [Score=216, Expect=2e-65]} {RNA1509_19728, RNA1509_46985} {RNA1310_14048, RNA1509_19728, RNA1509_46985} {RNA1509_19728, RNA1509_46985, RNA815_7193.1}
60. MligTC455_21326 594 12.37 Mlig455_053950

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.860

Region-enriched R2: 1.783/0.00317

 CELSR3 2.619 - - 0.766 0.966 0.887 - Mlig455_053950 {REF} {Length: 2037} {Pfam: EGF domain [PF12947.9, score=40.5]; EGF-like domain [PF00008.29, score=21.7]; Coagulation Factor Xa inhibitory site [PF14670.8, score=20.6]; EGF-like domain [PF07974.15, score=19.4]} {Human: ENSG00000008300, CELSR3, cadherin EGF LAG seven-pass G-type receptor 3, [Score=50.4, Expect=7e-06]; ENSG00000010327, STAB1, stabilin 1, [Score=49.7, Expect=1e-05]} {Mouse: ENSMUSG00000061601, Pclo, piccolo (presynaptic cytomatrix protein), [Score=56.6, Expect=6e-08]; ENSMUSG00000107269, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [Score=53.9, Expect=4e-07]; ENSMUSG00000023473, Celsr3, cadherin, EGF LAG seven-pass G-type receptor 3, [Score=53.9, Expect=4e-07]} {Celegans: WBGene00013138, Y53C10A.10, [Score=55.1, Expect=9e-08]} {RNA1509_18483, RNA1509_28678} {RNA1310_10853, RNA1509_18483} {RNA1509_18483, RNA815_7106}
61. MligTC455_24074 1066 22.21 Mlig455_048222

Neo: -

Age: -

Region-enriched R2: 1.734/0.02628

 2.617 - - 0.794 0.976 0.847 - Mlig455_048222 {REF} {Length: 2364} {Smed: dd_Smed_v6_8763_0_1, dd_Smed_v6_8763_0_1, [RH, Score=101, Expect=1e-23]} {RNA1509_5814} {RNA1310_13945, RNA1509_5814} {RNA1509_5814, RNA815_5072}
62. MligTC455_40497 258 5.37 Mlig455_005650

Neo: -

Age: -

Region-enriched R2: 3.635/0.02759

 SLC1A2 2.616 - - 0.967 0.795 0.854 - Mlig455_005650 {REF} {Length: 2712} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=259.1]} {Human: ENSG00000110436, SLC1A2, solute carrier family 1 member 2, [Score=214, Expect=1e-61]; ENSG00000162383, SLC1A7, solute carrier family 1 member 7, [Score=212, Expect=4e-61]; ENSG00000079215, SLC1A3, solute carrier family 1 member 3, [Score=211, Expect=6e-61]; ENSG00000106688, SLC1A1, solute carrier family 1 member 1, [Score=207, Expect=1e-59]; ENSG00000105143, SLC1A6, solute carrier family 1 member 6, [Score=204, Expect=7e-58]} {Mouse: ENSMUSG00000005089, Slc1a2, solute carrier family 1 (glial high affinity glutamate transporter), member 2, [Score=229, Expect=3e-67]; ENSMUSG00000020142, Slc1a4, solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, [Score=225, Expect=3e-66]; ENSMUSG00000001918, Slc1a5, solute carrier family 1 (neutral amino acid transporter), member 5, [Score=221, Expect=1e-64]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [Score=216, Expect=2e-63]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=235, Expect=1e-70]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=231, Expect=2e-69]} {RNA1509_23441, RNA1509_40224, RNA1509_45320} {RNA1310_8169.3, RNA1509_23441, RNA1509_40224, RNA1509_45320} {RNA1509_23441, RNA1509_40224, RNA1509_45320, RNA815_2675.1}
63. MligTC455_21327 576 11.99 Mlig455_060627

Neo: -

Age: -

Region-enriched R2: 1.769/0.00469

 RRBP1 2.614 - - 0.764 0.960 0.890 - Mlig455_060627 {REF} {Length: 5289} {Pfam: EGF domain [PF12947.9, score=36.7]; Coagulation Factor Xa inhibitory site [PF14670.8, score=19.9]} {Human: ENSG00000125844, RRBP1, ribosome binding protein 1, [Score=120, Expect=3e-27]} {Mouse: ENSMUSG00000099398, Ms4a14, membrane-spanning 4-domains, subfamily A, member 14, [Score=89.0, Expect=1e-17]} {Celegans: WBGene00013138, Y53C10A.10, [Score=65.1, Expect=2e-10]} {RNA1509_28678, RNA1509_48202} {RNA1310_10853, RNA1509_48202} {RNA1509_48202, RNA815_7106}
64. MligTC455_21297 546 11.38 Mlig455_033973

Neo: Germline

Age: Up-Down-Up

 2.607 - - 0.920 0.726 - 0.961 Mlig455_033973 {REF} {Length: 4638} {RNA1509_49102} {RNA1310_24684} {RNA815_56598}
65. MligTC455_44972 344 7.16 Mlig455_020200

Neo: -

Age: -

 CEP72 2.606 - - 0.871 0.777 - 0.958 Mlig455_020200 {REF} {Length: 3284} {Pfam: Leucine-rich repeat [PF14580.8, score=42.1]} {Human: ENSG00000112877, CEP72, centrosomal protein 72, [RH, Score=149, Expect=4e-37]; ENSG00000280688, CEP72, centrosomal protein 72, [RH, Score=143, Expect=3e-39]} {Mouse: ENSMUSG00000021572, Cep72, centrosomal protein 72, [RH, Score=153, Expect=1e-38]} {Smed: dd_Smed_v6_12835_0_1, dd_Smed_v6_12835_0_1, [RH, Score=174, Expect=3e-47]} {RNA1509_31408} {RNA1310_4875, RNA1509_31408} {RNA1509_31408, RNA815_15532}
66. MligTC455_25395 2547 53.06 Mlig455_012103, Mlig455_029022

Neo: -

Age: -

 SLC46A3 2.592 - - 0.863 0.749 0.980 -

Mlig455_012103 {REF} {Length: 2488} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.5]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=139, Expect=2e-35]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=5e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=2e-50]} {RNA1509_18925, RNA1509_45956} {RNA1310_14130.1, RNA1509_18925, RNA1509_45956} {RNA1509_18925, RNA1509_45956, RNA815_4522}

Mlig455_029022 {REF} {Length: 2776} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.1]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=142, Expect=2e-36]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=4e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=3e-50]} {RNA1509_18925} {RNA1310_14130.2} {RNA815_4522}
67. MligTC455_05193 189 3.94 Mlig455_013094

Neo: -

Age: Down-Up-Down

 BCHE 2.584 - - 0.775 - 0.850 0.959 Mlig455_013094 {REF} {Length: 2979} {Pfam: Carboxylesterase family [PF00135.30, score=435.7]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [RH, Score=319, Expect=5e-100]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [RH, Score=334, Expect=3e-105]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=253, Expect=3e-74]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [RH, Score=332, Expect=2e-104]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=416, Expect=5e-136]} {RNA1509_5880} {RNA1310_9146.1} {RNA815_3169.2}
68. MligTC455_25464 185 3.85 Mlig455_001339

Neo: -

Age: -

Region-enriched R2: 4.725/0.00025

 2.583 - - 0.951 0.730 0.902 - Mlig455_001339 {REF} {Length: 1386} {RNA1509_58508} {RNA1310_32754, RNA1509_58508} {RNA1509_58508, RNA815_47065}
69. MligTC455_23643 406 8.46 Mlig455_067289

Neo: -

Age: Down-Up-Up

 STK33 2.58 - - - 0.855 0.755 0.970 Mlig455_067289 {REF} {Length: 2596} {Pfam: Protein kinase domain [PF00069.27, score=206.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=137.9]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=22.3]} {Human: ENSG00000130413, STK33, serine/threonine kinase 33, [Score=184, Expect=7e-53]} {Mouse: ENSMUSG00000031027, Stk33, serine/threonine kinase 33, [Score=190, Expect=4e-55]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=137, Expect=2e-36]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=129, Expect=5e-34]} {Smed: dd_Smed_v6_12461_0_1, dd_Smed_v6_12461_0_1, [RH, Score=231, Expect=1e-72]} {RNA1509_36009} {RNA1310_11665} {RNA815_6928}
70. MligTC455_43338 3043 63.4 Mlig455_057398, Mlig455_059559

Neo: -

Age: logFC(26M/2M)=-0.259

Region-enriched R2: 1.086/0.00779

 CYB5D1 2.58 - - - 0.792 0.824 0.964

Mlig455_057398 {REF} {Length: 1138} {Pfam: Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.8]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [Score=215, Expect=1e-70]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [Score=223, Expect=7e-74]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [Score=221, Expect=3e-73]} {RNA1509_11346} {RNA1310_26198} {RNA815_11579}

Mlig455_059559 {REF} {Length: 1306} {Pfam: Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=35.0]; Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.5]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [RH, Score=260, Expect=6e-88]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [RH, Score=263, Expect=2e-89]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [RH, Score=260, Expect=3e-88]} {RNA1509_5289} {RNA1310_26198, RNA1509_5289} {RNA1509_5289, RNA815_11579}
71. MligTC455_33876 123 2.56 Mlig455_030510

Neo: -

Age: -

 2.566 - - - 0.826 0.782 0.958 Mlig455_030510 {REF} {Length: 1004} {RNA1509_42280} {RNA1310_51836} {RNA815_8810.1}
72. MligTC455_25532 631 13.14 Mlig455_000168

Neo: -

Age: -

 2.563 - - - 0.880 0.716 0.967 Mlig455_000168 {REF} {Length: 1851} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=32.8]} {RNA1509_57829} {RNA1310_16312} {RNA815_15052}
73. MligTC455_28447 1671 34.81 Mlig455_066308

Neo: -

Age: Down-Up-Down

 2.558 - - - 0.887 0.707 0.964 Mlig455_066308 {REF} {Length: 1281} {Pfam: Domain of unknown function (DUF4515) [PF14988.8, score=104.5]} {Mouse: ENSMUSG00000098176, Ccdc166, coiled-coil domain containing 166, [RH, Score=107, Expect=4e-26]} {Smed: dd_Smed_v6_13384_0_1, dd_Smed_v6_13384_0_1, [RH, Score=124, Expect=2e-33]} {RNA1509_33127} {RNA1310_32791.1, RNA1509_33127} {RNA1509_33127, RNA815_15652}
74. MligTC455_37811 192 3.99 Mlig455_010190, Mlig455_058688

Neo: -

Age: Down-Up-Down

 2.548 0.766 - - - 0.826 0.956

Mlig455_010190 {REF} {Length: 2948} {Smed: dd_Smed_v6_62611_0_1, dd_Smed_v6_62611_0_1, [RH, Score=71.6, Expect=3e-15]} {RNA1509_46223} {RNA1310_14882} {RNA815_30586}

Mlig455_058688 {REF} {Length: 3085} {Smed: dd_Smed_v6_62611_0_1, dd_Smed_v6_62611_0_1, [RH, Score=71.6, Expect=3e-15]} {RNA1509_46223} {RNA1310_14882} {RNA815_30586}
75. MligTC455_10652 112 2.34 Mlig455_054198

Neo: -

Age: -

 2.544 - - 0.766 0.828 - 0.950 Mlig455_054198 {REF} {Length: 407} {NoTransDecoderORF}
76. MligTC455_43906 878 18.29 Mlig455_044333, Mlig455_044345

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.277

 RAI14 2.543 - - 0.847 0.734 0.962 -

Mlig455_044333 {REF} {Length: 5825} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=81.1]; Ankyrin repeat [PF00023.32, score=72.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.6]; Ankyrin repeat [PF13606.8, score=48.5]; Ankyrin repeats (many copies) [PF13857.8, score=44.2]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=90.1, Expect=3e-17]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=94.4, Expect=9e-19]; ENSMUSG00000007827, Ankrd26, ankyrin repeat domain 26, [Score=89.7, Expect=3e-17]} {Dmel: FBgn0039590, CG10011, [Score=82.4, Expect=4e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=85.9, Expect=3e-16]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=73.9, Expect=7e-13]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}

Mlig455_044345 {REF} {Length: 6035} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=87.7]; Ankyrin repeat [PF00023.32, score=72.9]; Ankyrin repeats (many copies) [PF13637.8, score=66.8]; Ankyrin repeats (many copies) [PF13857.8, score=50.5]; Ankyrin repeat [PF13606.8, score=50.0]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=94.7, Expect=9e-19]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=92.0, Expect=6e-19]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=99.4, Expect=3e-20]} {Dmel: FBgn0039590, CG10011, [Score=87.4, Expect=1e-16]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=86.3, Expect=2e-16]} {Smed: dd_Smed_v6_7952_0_2, dd_Smed_v6_7952_0_2, [Score=80.5, Expect=8e-15]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}
77. MligTC455_40325 103 2.15 Mlig455_013035

Neo: -

Age: -

 2.528 - - 0.792 0.762 0.974 - Mlig455_013035 {REF} {Length: 653} {RNA1509_20946} {RNA1310_44606} {RNA815_35640}
78. MligTC455_54157 234 4.88 Mlig455_058424

Neo: -

Age: -

 PPP1R36 2.526 0.814 0.727 - - - 0.985 Mlig455_058424 {REF} {Length: 2441} {Pfam: Protein phosphatase 1 inhibitor [PF14895.8, score=139.0]} {Human: ENSG00000165807, PPP1R36, protein phosphatase 1 regulatory subunit 36, [RH, Score=191, Expect=1e-55]} {Mouse: ENSMUSG00000052221, Ppp1r36, protein phosphatase 1, regulatory subunit 36, [RH, Score=167, Expect=5e-47]} {RNA1509_6292} {RNA1310_2911.1} {RNA815_5971.1}
79. MligTC455_24359 269 5.6 Mlig455_061470

Neo: -

Age: logFC(26M/2M)=-0.300

 2.522 - - 0.739 - 0.818 0.965 Mlig455_061470 {REF} {Length: 1541} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=44.6]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=189, Expect=6e-60]} {RNA1509_15325, RNA1509_47076} {RNA1310_24934.1, RNA1509_15325, RNA1509_47076} {RNA1509_15325, RNA1509_47076, RNA815_10915.1}
80. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

 ROR1 2.517 0.746 - - 0.808 0.963 - Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
81. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

 ANGPTL1 2.511 0.712 - - 0.830 0.969 -

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
82. MligTC455_44986 2417 50.36 Mlig455_002882

Neo: -

Age: logFC(26M/2M)=-0.453

 2.506 - - 0.963 0.713 0.830 - Mlig455_002882 {REF} {Length: 1187} {RNA1509_10653, RNA1509_6260} {RNA1310_22176, RNA1509_10653, RNA1509_6260} {RNA1509_10653, RNA1509_6260, RNA815_9068}
83. MligTC455_51933 583 12.15 Mlig455_024511

Neo: -

Age: logFC(26M/2M)=-0.429

Region-enriched R2: 2.089/0.00081

 CBSL 2.505 - - 0.730 0.825 0.950 - Mlig455_024511 {REF} {Length: 1959} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=138.0]; CBS domain [PF00571.30, score=48.9]} {Human: ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=463, Expect=3e-160]; ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=463, Expect=3e-160]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=467, Expect=6e-162]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=327, Expect=2e-107]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=264, Expect=2e-81]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=511, Expect=6e-180]} {RNA1509_36721} {RNA1310_10809} {RNA815_3797.1}
84. MligTC455_07422 104 2.17 Mlig455_059513

Neo: -

Age: -

 SLC22A13 2.501 - - 0.959 0.730 0.812 - Mlig455_059513 {REF} {Length: 3916} {Pfam: Sugar (and other) transporter [PF00083.26, score=103.6]; Major Facilitator Superfamily [PF07690.18, score=44.3]} {Human: ENSG00000172940, SLC22A13, solute carrier family 22 member 13, [Score=195, Expect=5e-53]; ENSG00000112499, SLC22A2, solute carrier family 22 member 2, [Score=189, Expect=4e-51]; ENSG00000146477, SLC22A3, solute carrier family 22 member 3, [Score=186, Expect=5e-50]} {Mouse: ENSMUSG00000023829, Slc22a1, solute carrier family 22 (organic cation transporter), member 1, [Score=189, Expect=4e-51]; ENSMUSG00000040966, Slc22a2, solute carrier family 22 (organic cation transporter), member 2, [Score=188, Expect=5e-51]; ENSMUSG00000074028, Slc22a13, solute carrier family 22 (organic cation transporter), member 13, [Score=186, Expect=4e-50]; ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=184, Expect=2e-49]} {Dmel: FBgn0086365, Orct2, Organic cation transporter 2, [Score=206, Expect=4e-57]} {Celegans: WBGene00022348, Y82E9BR.16, [Score=167, Expect=1e-43]} {Smed: dd_Smed_v6_11120_0_1, dd_Smed_v6_11120_0_1, [RH, Score=205, Expect=2e-57]} {RNA1509_56460} {RNA1310_33118, RNA1509_56460} {RNA1509_56460, RNA815_21922}
85. MligTC455_15662 187 3.89 Mlig455_030386

Neo: -

Age: -

Region-enriched R2: 3.832/0.01388

Regeneration-upregulated BL: 4.705

Regeneration-enriched BL: 4.705

 NR2E1 2.494 - - 0.952 0.797 0.745 - Mlig455_030386 {REF} {Length: 2439} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=98.4]; Ligand-binding domain of nuclear hormone receptor [PF00104.32, score=73.9]} {Human: ENSG00000112333, NR2E1, nuclear receptor subfamily 2 group E member 1, [RH, Score=190, Expect=8e-54]} {Mouse: ENSMUSG00000019803, Nr2e1, nuclear receptor subfamily 2, group E, member 1, [Score=190, Expect=2e-54]} {Dmel: FBgn0003720, tll, tailless, [RH, Score=205, Expect=3e-59]} {Celegans: WBGene00003657, nhr-67, Nuclear hormone receptor family member nhr-67, [RH, Score=194, Expect=1e-55]} {Smed: dd_Smed_v6_21347_0_1, dd_Smed_v6_21347_0_1, [RH, Score=189, Expect=4e-54]} {RNA1509_39776} {RNA1310_21550} {RNA815_27099.1}
86. MligTC455_48010 177 3.69 Mlig455_051923

Neo: -

Age: logFC(26M/2M)=-0.400

 2.494 0.722 - - 0.813 0.959 - Mlig455_051923 {REF} {Length: 1181} {Smed: dd_Smed_v6_2217_0_1, dd_Smed_v6_2217_0_1, [RH, Score=54.7, Expect=4e-10]} {RNA1509_30673} {RNA1310_38150} {RNA815_20383}
87. MligTC455_43667 251 5.24 Mlig455_070631

Neo: -

Age: Down-Down-Up

 KY 2.491 - - 0.765 0.742 0.984 - Mlig455_070631 {REF} {Length: 5010} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=151, Expect=4e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=2e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=136, Expect=4e-32]} {RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1310_2203, RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1509_26818, RNA1509_52206, RNA1509_7582, RNA815_6135}
88. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

 ROR1 2.484 0.710 - - 0.813 0.961 - Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
89. MligTC455_16641 1524 31.75 Mlig455_043685, Mlig455_043752, Mlig455_047473

Neo: -

Age: Down-Up-Up

Region-enriched R8: 2.371/0.00579

 2.477 - - 0.955 0.704 0.818 -

Mlig455_043685 {REF} {Length: 1558} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=104.2]} {Smed: dd_Smed_v6_13989_0_1, dd_Smed_v6_13989_0_1, [Score=60.1, Expect=6e-10]} {RNA1509_51030} {RNA1310_23381} {RNA815_11328}

Mlig455_043752 {REF} {Length: 1659} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=104.5]} {Smed: dd_Smed_v6_13989_0_1, dd_Smed_v6_13989_0_1, [Score=59.3, Expect=1e-09]} {RNA1509_51030} {RNA1310_23381} {RNA815_11328}

Mlig455_047473 {REF} {Length: 1659} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=104.5]} {Smed: dd_Smed_v6_13989_0_1, dd_Smed_v6_13989_0_1, [Score=59.3, Expect=1e-09]} {RNA1509_18230, RNA1509_43643, RNA1509_51030} {RNA1310_23381, RNA1509_18230, RNA1509_43643, RNA1509_51030} {RNA1509_18230, RNA1509_43643, RNA1509_51030, RNA815_11328}
90. MligTC455_52709 4470 93.12 Mlig455_056728

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.481

 CROCC 2.476 - - 0.954 0.808 0.714 - Mlig455_056728 {REF} {Length: 9759} {Pfam: Ciliary rootlet component, centrosome cohesion [PF15035.8, score=193.2]; Septation ring formation regulator, EzrA [PF06160.14, score=19.1]} {Human: ENSG00000058453, CROCC, ciliary rootlet coiled-coil, rootletin, [Score=841, Expect=0.0]} {Mouse: ENSMUSG00000040860, Crocc, ciliary rootlet coiled-coil, rootletin, [Score=845, Expect=0.0]} {Dmel: FBgn0039152, Root, Rootletin, [Score=372, Expect=9e-104]} {Celegans: WBGene00022500, lfi-1, Lin-5 (Five) Interacting protein, [RH, Score=165, Expect=2e-40]} {Smed: dd_Smed_v6_1404_0_1, dd_Smed_v6_1404_0_1, [RH, Score=1895, Expect=0.0]} {RNA1509_137} {RNA1310_2877.1} {RNA815_204}
91. MligTC455_31916 78 1.63 Mlig455_067080

Neo: -

Age: -

 2.465 - - 0.967 0.729 0.769 - Mlig455_067080 {REF} {Length: 1168} {NoTransDecoderORF} {RNA1509_48060} {RNA1310_6149} {RNA815_1772.1}
92. MligTC455_19455 23 0.48 Mlig455_059587

Neo: -

Age: Up-Down-Down

 2.458 - - 0.961 0.722 0.775 - Mlig455_059587 {REF} {Length: 1356} {Pfam: FAM216B protein family [PF15107.8, score=21.6]} {RNA1310_31687} {RNA815_40824}
93. MligTC455_11452 34 0.7 Mlig455_059243

Neo: -

Age: -

 2.451 - - 0.767 0.722 0.962 - Mlig455_059243 {REF} {Length: 1221} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=20.8]} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
94. MligTC455_36042 217 4.53 Mlig455_046386

Neo: -

Age: -

 LOXHD1 2.434 0.714 - 0.955 0.765 - - Mlig455_046386 {REF} {Length: 3021} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=52.2]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=75.9, Expect=2e-13]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=76.6, Expect=5e-14]} {Smed: dd_Smed_v6_39713_0_1, dd_Smed_v6_39713_0_1, [RH, Score=81.3, Expect=4e-16]} {RNA1509_25188} {RNA1310_11606} {RNA815_15282}
95. MligTC455_52083 972 20.26 Mlig455_009237, Mlig455_009643

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.031/0.00909

 FAT3 2.389 - - - 0.736 0.952 0.701

Mlig455_009237 {REF} {Length: 9383} {Pfam: Cadherin domain [PF00028.19, score=291.4]; Laminin G domain [PF02210.26, score=96.4]; Cadherin cytoplasmic region [PF01049.19, score=79.9]; Laminin G domain [PF00054.25, score=77.7]; Cadherin-like [PF16184.7, score=57.2]; Cadherin-like [PF08266.14, score=20.1]} {Human: ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]; ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=280, Expect=1e-74]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=279, Expect=3e-74]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=716, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=478, Expect=2e-135]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=175, Expect=4e-43]} {RNA1509_5439} {RNA1310_149} {RNA815_168}

Mlig455_009643 {REF} {Length: 9400} {Pfam: Cadherin domain [PF00028.19, score=300.2]; Laminin G domain [PF02210.26, score=97.0]; Cadherin cytoplasmic region [PF01049.19, score=80.9]; Laminin G domain [PF00054.25, score=78.3]; Cadherin-like [PF16184.7, score=54.5]; Cadherin-like [PF08266.14, score=22.1]} {Human: ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]; ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=275, Expect=3e-73]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=720, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=468, Expect=2e-132]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=169, Expect=1e-41]} {RNA1509_5439} {RNA1310_149, RNA1509_5439} {RNA1509_5439, RNA815_168}
96. MligTC455_30223 110 2.29 Mlig455_025799

Neo: -

Age: Down-Down-Down

 PIF1 1.905 - - - - 0.965 0.940 Mlig455_025799 {REF} {Length: 9227} {Pfam: PIF1-like helicase [PF05970.16, score=333.7]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.7]; AAA domain [PF13604.8, score=45.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.5]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=2e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=122, Expect=5e-28]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=116, Expect=4e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
97. MligTC455_43293 2619 54.57 Mlig455_001393

Neo: -

Age: -

Region-specific R2: 1.579

 ANXA7 1.894 - - 0.979 - 0.915 - Mlig455_001393 {REF} {Length: 4698} {Pfam: Annexin [PF00191.22, score=268.6]} {Human: ENSG00000138279, ANXA7, annexin A7, [RH, Score=307, Expect=6e-98]} {Mouse: ENSMUSG00000021814, Anxa7, annexin A7, [RH, Score=301, Expect=8e-96]} {Dmel: FBgn0000083, AnxB9, Annexin B9, [Score=259, Expect=4e-82]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=261, Expect=2e-81]} {Smed: dd_Smed_v6_1735_0_1, dd_Smed_v6_1735_0_1, [Score=270, Expect=6e-86]} {RNA1509_5239} {RNA1310_11340, RNA1509_5239} {RNA1509_5239, RNA815_3977}
98. MligTC455_33343 459 9.56 Mlig455_063303

Neo: -

Age: -

Region-enriched R2: 1.600/0.01675

 ITPR1 1.892 - - - 0.928 0.964 - Mlig455_063303 {REF} {Length: 3962} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=68.3]; Ion transport protein [PF00520.33, score=28.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=166, Expect=6e-41]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=182, Expect=7e-46]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=179, Expect=4e-45]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=155, Expect=5e-38]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1044, Expect=0.0]} {RNA1509_30811} {RNA1310_939} {RNA815_220}
99. MligTC455_37654 406 8.47 Mlig455_029446, Mlig455_029466

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.381

Region-enriched R7: 2.220/0.02232

 LOXL2, LOXL4 1.887 - - - 0.935 0.952 -

Mlig455_029446 {REF} {Length: 2317} {Pfam: Lysyl oxidase [PF01186.19, score=223.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=92.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=31.8]} {Human: ENSG00000134013, LOXL2, lysyl oxidase like 2, [Score=232, Expect=1e-68]; ENSG00000138131, LOXL4, lysyl oxidase like 4, [Score=223, Expect=4e-65]} {Mouse: ENSMUSG00000034205, Loxl2, lysyl oxidase-like 2, [Score=224, Expect=7e-66]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [Score=216, Expect=8e-63]; ENSMUSG00000000693, Loxl3, lysyl oxidase-like 3, [Score=213, Expect=9e-62]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [Score=255, Expect=8e-80]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [Score=277, Expect=6e-89]} {RNA1509_58726} {RNA1310_16786} {RNA815_6954}

Mlig455_029466 {REF} {Length: 2102} {Pfam: Lysyl oxidase [PF01186.19, score=261.1]; Scavenger receptor cysteine-rich domain [PF00530.20, score=107.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=30.3]} {Human: ENSG00000138131, LOXL4, lysyl oxidase like 4, [RH, Score=278, Expect=5e-83]; ENSG00000134013, LOXL2, lysyl oxidase like 2, [RH, Score=277, Expect=1e-82]; ENSG00000115318, LOXL3, lysyl oxidase like 3, [RH, Score=273, Expect=4e-81]} {Mouse: ENSMUSG00000000693, Loxl3, lysyl oxidase-like 3, [RH, Score=270, Expect=3e-80]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [RH, Score=269, Expect=6e-80]; ENSMUSG00000034205, Loxl2, lysyl oxidase-like 2, [RH, Score=259, Expect=5e-76]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [RH, Score=330, Expect=7e-106]} {Celegans: WBGene00015646, mlt-10, [Score=132, Expect=5e-32]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [RH, Score=358, Expect=2e-117]} {RNA1509_58726} {RNA1310_16786} {RNA815_6954}
100. MligTC455_29164 899 18.73 Mlig455_006856

Neo: -

Age: Down-Up-Up

 ANKRD42 1.884 - - - 0.913 0.971 - Mlig455_006856 {REF} {Length: 2038} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=124.3]; Ankyrin repeats (3 copies) [PF12796.9, score=118.0]; Ankyrin repeats (many copies) [PF13857.8, score=106.6]; Ankyrin repeat [PF13606.8, score=85.3]; Ankyrin repeat [PF00023.32, score=69.9]} {Human: ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [RH, Score=493, Expect=2e-170]} {Mouse: ENSMUSG00000041343, Ankrd42, ankyrin repeat domain 42, [RH, Score=491, Expect=1e-169]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=143, Expect=1e-35]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=125, Expect=4e-30]} {Smed: dd_Smed_v6_10615_0_1, dd_Smed_v6_10615_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_29991} {RNA1310_12980.1} {RNA815_2353.1}

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