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Results for MligTC455_52790

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_52790 69 1.44 Mlig455_031435

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.468

 KY Mlig455_031435 {REF} {Length: 2924} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=54.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [RH, Score=190, Expect=2e-51]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [RH, Score=190, Expect=2e-51]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=97.4, Expect=1e-20]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=96.3, Expect=8e-21]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=139, Expect=7e-34]} {RNA1509_41238} {RNA1310_9626} {RNA815_5945}

Cumulative graph for MligTC455_52790

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 5.19 1.178 0.02892 0.44135
RegionR2 -2.177 1.178 1.00000 1.00000
RegionR3 -1.798 1.178 0.99924 1.00000
RegionR4 1.764 1.178 0.27410 0.58054
RegionR5 0.481 1.178 0.63288 0.98597
RegionR6 -1.261 1.178 0.99442 1.00000
RegionR7 0.797 1.178 0.59463 1.00000
RegionR8 -2.997 1.178 0.48790 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -8.947 1.178 0.08054 0.77596
RegenerationR2 -0.644 1.178 0.71613 0.96222
RegenerationR3 0.276 1.178 0.80783 0.98437
RegenerationR4 -1.642 1.178 0.35760 0.78642
RegenerationR5 -1.228 1.178 0.47054 0.84210
RegenerationR6 -1.476 1.178 0.49758 0.80445
RegenerationBL -3.962 1.178 1.00000 1.00000
RegenerationTP 1.493 1.178 0.54787 0.93154


Genes with expression patterns similar to MligTC455_52790

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_52790 69 1.44 Mlig455_031435

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.468

 KY 3 - - 1.000 - 1.000 1.000 Mlig455_031435 {REF} {Length: 2924} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=54.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [RH, Score=190, Expect=2e-51]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [RH, Score=190, Expect=2e-51]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=97.4, Expect=1e-20]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=96.3, Expect=8e-21]} {Smed: dd_Smed_v6_1109_0_1, dd_Smed_v6_1109_0_1, [Score=139, Expect=7e-34]} {RNA1509_41238} {RNA1310_9626} {RNA815_5945}
2. MligTC455_15039 142 2.97 Mlig455_020475

Neo: -

Age: -

 1.909 - - 0.986 - - 0.923 Mlig455_020475 {REF} {Length: 1638} {TRANSSPLICED} {RNA1509_31753} {RNA1310_38494, RNA1509_31753} {RNA1509_31753, RNA815_20174}
3. MligTC455_44608 57 1.19 Mlig455_037186

Neo: -

Age: -

 1.891 - - 0.981 - 0.910 - Mlig455_037186 {REF} {Length: 1390} {RNA1509_59364} {RNA1310_14796} {RNA815_18066}
4. MligTC455_22830 80 1.68 Mlig455_009442

Neo: -

Age: -

 1.877 - - - - 0.984 0.893 Mlig455_009442 {REF} {Length: 1081} {NoTransDecoderORF} {RNA1509_57421} {RNA1310_25119} {RNA815_11593}
5. MligTC455_37412 95 1.98 Mlig455_036605, Mlig455_036645

Neo: -

Age: -

 ADRA2A 1.876 - - 0.986 - 0.890 -

Mlig455_036605 {REF} {Length: 3015} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=97.8]} {Human: ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=55.5, Expect=2e-07]; ENSG00000082556, OPRK1, opioid receptor kappa 1, [Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=56.6, Expect=5e-08]} {Dmel: FBgn0053517, Dop2R, Dopamine 2-like receptor, [Score=64.7, Expect=1e-10]} {Celegans: WBGene00016037, dop-6, DOPamine receptor, [Score=52.4, Expect=7e-07]} {Smed: dd_Smed_v6_23525_0_1, dd_Smed_v6_23525_0_1, [RH, Score=136, Expect=5e-35]} {RNA1310_57451} {RNA815_47300}

Mlig455_036645 {REF} {Length: 3203} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=97.0]} {Human: ENSG00000150594, ADRA2A, adrenoceptor alpha 2A, [Score=55.5, Expect=2e-07]; ENSG00000082556, OPRK1, opioid receptor kappa 1, [Score=55.1, Expect=1e-07]} {Mouse: ENSMUSG00000033717, Adra2a, adrenergic receptor, alpha 2a, [Score=56.6, Expect=4e-08]} {Dmel: FBgn0053517, Dop2R, Dopamine 2-like receptor, [Score=63.2, Expect=4e-10]} {Celegans: WBGene00016037, dop-6, DOPamine receptor, [Score=52.4, Expect=6e-07]} {Smed: dd_Smed_v6_23525_0_1, dd_Smed_v6_23525_0_1, [RH, Score=136, Expect=6e-35]} {RNA1310_57451} {RNA815_47300}
6. MligTC455_46241 700 14.59 Mlig455_021193, Mlig455_028384, Mlig455_035962, Mlig455_056116, Mlig455_056268

Neo: -

Age: Down-Up-Down

 1.866 - - 0.979 - 0.887 -

Mlig455_021193 {REF} {Length: 400} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45287} {RNA1310_90539} {RNA815_49421}

Mlig455_028384 {REF} {Length: 999} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45287} {RNA1310_22899.1} {RNA815_49421}

Mlig455_035962 {REF} {Length: 1078} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45287} {RNA1310_22899.1} {RNA815_38929}

Mlig455_056116 {REF} {Length: 1084} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45287} {RNA1310_22899.1} {RNA815_38929}

Mlig455_056268 {REF} {Length: 983} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45287} {RNA1310_22899.1} {RNA815_49421}
7. MligTC455_09101 65 1.36 Mlig455_027894

Neo: -

Age: -

 1.86 - - 0.985 - 0.875 - Mlig455_027894 {REF} {Length: 1814} {NoTransDecoderORF} {RNA1509_52098} {RNA1310_24226} {RNA815_14343.1}
8. MligTC455_20346 169 3.51 Mlig455_045662

Neo: -

Age: -

 1.831 - - 0.985 - - 0.846 Mlig455_045662 {REF} {Length: 1251} {TRANSSPLICED} {RNA1509_12723, RNA1509_49607} {RNA1310_26083, RNA1509_49607} {RNA1509_49607, RNA815_11437}
9. MligTC455_38716 85 1.77 Mlig455_046305, Mlig455_046972

Neo: -

Age: Down-Up-Up

 1.826 - - 0.990 - - 0.836

Mlig455_046305 {REF} {Length: 1228} {RNA1310_12695} {RNA815_13607}

Mlig455_046972 {REF} {Length: 1382} {RNA1310_12695} {RNA815_35415}
10. MligTC455_43192 420 8.75 Mlig455_010853, Mlig455_010884

Neo: -

Age: -

Region-enriched R3: 5.568/0.01380

 1.823 - - 0.973 - 0.850 -

Mlig455_010853 {REF} {Length: 897} {RNA1310_121983}

Mlig455_010884 {REF} {Length: 898} {RNA1310_121983}
11. MligTC455_37724 781 16.28 Mlig455_065465

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.698

 ROR1 1.807 - - 0.959 - 0.848 - Mlig455_065465 {REF} {Length: 4059} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=240.2]; Protein kinase domain [PF00069.27, score=101.6]; Immunoglobulin I-set domain [PF07679.18, score=45.2]; Immunoglobulin domain [PF13927.8, score=42.8]; Fz domain [PF01392.24, score=34.0]; Immunoglobulin domain [PF13895.8, score=32.3]; Immunoglobulin domain [PF00047.27, score=24.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=398, Expect=5e-123]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=402, Expect=6e-125]} {Dmel: FBgn0010407, Ror, [Score=276, Expect=1e-80]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [RH, Score=220, Expect=1e-59]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=398, Expect=3e-124]} {RNA1509_15729, RNA1509_49184} {RNA1310_2781.1, RNA1509_15729, RNA1509_49184} {RNA1509_15729, RNA1509_49184, RNA815_11745}
12. MligTC455_10714 75 1.57 Mlig455_014408, Mlig455_070162

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.165

Region-enriched R4: 4.566/0.03282

 RSPH9 1.789 - - 0.986 - - 0.803

Mlig455_014408 {REF} {Length: 742} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=26.0]} {Human: ENSG00000172426, RSPH9, radial spoke head 9 homolog, [Score=122, Expect=6e-33]} {Mouse: ENSMUSG00000023966, Rsph9, radial spoke head 9 homolog (Chlamydomonas), [Score=120, Expect=1e-32]} {Dmel: FBgn0051803, CG31803, [Score=85.1, Expect=2e-19]} {Smed: dd_Smed_v6_4707_0_1, dd_Smed_v6_4707_0_1, [Score=182, Expect=1e-56]} {RNA1509_33851} {RNA1310_6070} {RNA815_13422}

Mlig455_070162 {REF} {Length: 1222} {TRANSSPLICED} {Pfam: Radial spokehead-like protein [PF04712.14, score=45.8]} {Human: ENSG00000172426, RSPH9, radial spoke head 9 homolog, [RH, Score=278, Expect=1e-91]} {Mouse: ENSMUSG00000023966, Rsph9, radial spoke head 9 homolog (Chlamydomonas), [RH, Score=270, Expect=1e-88]} {Dmel: FBgn0051803, CG31803, [RH, Score=178, Expect=6e-53]} {Smed: dd_Smed_v6_4707_0_1, dd_Smed_v6_4707_0_1, [RH, Score=364, Expect=6e-126]} {RNA1509_33851} {RNA1310_6070} {RNA815_13422}
13. MligTC455_15564 86 1.79 Mlig455_054618

Neo: -

Age: -

 1.789 - - 0.979 - - 0.810 Mlig455_054618 {REF} {Length: 920} {NoTransDecoderORF} {RNA1310_55174} {RNA815_12298}
14. MligTC455_33206 149 3.11 Mlig455_032067

Neo: -

Age: Down-Down-Up

Region-enriched R7: 2.633/0.00379

 PCSK7 1.789 - - - - 0.950 0.839 Mlig455_032067 {REF} {Length: 3596} {Pfam: Subtilase family [PF00082.24, score=141.9]; Proprotein convertase P-domain [PF01483.22, score=81.5]; Peptidase S8 pro-domain [PF16470.7, score=34.4]} {Human: ENSG00000160613, PCSK7, proprotein convertase subtilisin/kexin type 7, [RH, Score=481, Expect=4e-158]} {Mouse: ENSMUSG00000035382, Pcsk7, proprotein convertase subtilisin/kexin type 7, [RH, Score=486, Expect=1e-160]} {Dmel: FBgn0004598, Fur2, Furin 2, [Score=345, Expect=1e-101]} {Celegans: WBGene00002232, kpc-1, Furin-like protease kpc-1, [Score=354, Expect=3e-111]} {Smed: dd_Smed_v6_10832_0_1, dd_Smed_v6_10832_0_1, [Score=344, Expect=4e-108]} {RNA1509_52655} {RNA1310_18882, RNA1509_52655} {RNA1509_52655, RNA815_14719.1}
15. MligTC455_20345 142 2.97 Mlig455_045604

Neo: Int S/G2/M

Age: -

 1.787 - - 0.976 - - 0.811 Mlig455_045604 {REF} {Length: 1829} {RNA1509_12723} {RNA1310_26083} {RNA815_11437}
16. MligTC455_08411 363 7.56 Mlig455_009411, Mlig455_016107, Mlig455_036911

Neo: -

Age: logFC(26M/2M)=-0.389

 1.778 - - 0.976 - - 0.802

Mlig455_009411 {REF} {Length: 2437} {Pfam: Innexin [PF00876.20, score=308.4]} {Dmel: FBgn0085387, shakB, shaking B, [Score=85.9, Expect=7e-18]} {Celegans: WBGene00006747, unc-7, Innexin unc-7, [Score=212, Expect=2e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=297, Expect=5e-96]} {RNA1509_24217} {RNA1310_17123} {RNA815_15903}

Mlig455_016107 {REF} {Length: 2483} {Pfam: Innexin [PF00876.20, score=308.4]} {Dmel: FBgn0085387, shakB, shaking B, [Score=85.9, Expect=7e-18]} {Celegans: WBGene00006747, unc-7, Innexin unc-7, [Score=212, Expect=2e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=297, Expect=5e-96]} {RNA1509_24217} {RNA1310_17123} {RNA815_15903}

Mlig455_036911 {REF} {Length: 2682} {Pfam: Innexin [PF00876.20, score=305.6]} {Dmel: FBgn0085387, shakB, shaking B, [Score=87.8, Expect=2e-18]} {Celegans: WBGene00006747, unc-7, Innexin unc-7, [Score=209, Expect=1e-61]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=296, Expect=3e-95]} {RNA1509_24217} {RNA1310_17123} {RNA815_15903}
17. MligTC455_43663 88 1.83 Mlig455_070157

Neo: -

Age: Up-Down-Up

 1.774 - - 0.981 - - 0.793 Mlig455_070157 {REF} {Length: 2611} {RNA1310_65373} {RNA815_37965}
18. MligTC455_31303 30 0.62 Mlig455_044317

Neo: Irradiation

Age: Up-Down-Down

 GABBR2 1.773 - - 0.985 - 0.788 - Mlig455_044317 {REF} {Length: 1464} {Pfam: 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=161.8]; Receptor family ligand binding region [PF01094.30, score=99.7]} {Human: ENSG00000136928, GABBR2, gamma-aminobutyric acid type B receptor subunit 2, [Score=231, Expect=2e-63]} {Mouse: ENSMUSG00000039809, Gabbr2, gamma-aminobutyric acid (GABA) B receptor, 2, [Score=228, Expect=1e-62]} {Dmel: FBgn0027575, GABA-B-R2, metabotropic GABA-B receptor subtype 2, [Score=221, Expect=6e-60]} {Celegans: WBGene00022675, gbb-2, GABA B receptor subunit; GABAB2 receptor subunit, [Score=209, Expect=1e-56]} {Smed: dd_Smed_v6_51663_0_1, dd_Smed_v6_51663_0_1, [Score=131, Expect=5e-34]} {RNA1509_26993} {RNA1310_7927.1} {RNA815_4866.1}
19. MligTC455_28192 612 12.76 Mlig455_032616, Mlig455_060467, Mlig455_060474

Neo: -

Age: -

 PIF1 1.77 - - 0.984 - - 0.786

Mlig455_032616 {REF} {Length: 2558} {TRANSSPLICED} {RNA1509_51272} {RNA1310_363} {RNA815_104.1}

Mlig455_060467 {REF} {Length: 508} {Pfam: PIF1-like helicase [PF05970.16, score=120.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=94.4]; AAA domain [PF13604.8, score=54.2]; AAA domain [PF13245.8, score=28.8]; Helicase [PF02689.16, score=24.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=23.9]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=130, Expect=3e-30]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=134, Expect=1e-31]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=130, Expect=2e-30]} {Celegans: WBGene00004028, pif-1, ATP-dependent DNA helicase PIF1, [Score=132, Expect=1e-31]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=128, Expect=8e-30]} {RNA1509_51272} {RNA1310_363} {RNA815_104.1}

Mlig455_060474 {REF} {Length: 1944} {TRANSSPLICED} {RNA1509_51272} {RNA1310_363} {RNA815_104.1}
20. MligTC455_46885 72 1.49 Mlig455_015138

Neo: -

Age: -

 PRKG2 1.759 - - 0.980 - 0.779 - Mlig455_015138 {REF} {Length: 3064} {Pfam: Protein kinase domain [PF00069.27, score=227.4]; Cyclic nucleotide-binding domain [PF00027.31, score=128.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=118.5]; Kinase-like [PF14531.8, score=25.1]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=674, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=682, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=668, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=676, Expect=0.0]} {RNA1509_26653} {RNA1310_15330.1} {RNA815_26005}
21. MligTC455_35937 341 7.1 Mlig455_065251

Neo: Neoblast

Age: -

 UHRF1 1.744 - - 0.989 - 0.755 - Mlig455_065251 {REF} {Length: 3600} {TRANSSPLICED} {Pfam: SAD/SRA domain [PF02182.19, score=185.9]; Tandem tudor domain within UHRF1 [PF12148.10, score=95.0]; Ubiquitin family [PF00240.25, score=57.9]; PHD-finger [PF00628.31, score=44.6]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=24.6]; zinc-RING finger domain [PF14634.8, score=23.6]; Ring finger domain [PF13639.8, score=21.3]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=19.9]; Prokaryotic RING finger family 4 [PF14447.8, score=18.8]} {Human: ENSG00000276043, UHRF1, ubiquitin like with PHD and ring finger domains 1, [RH, Score=622, Expect=0.0]} {Mouse: ENSMUSG00000001228, Uhrf1, ubiquitin-like, containing PHD and RING finger domains, 1, [RH, Score=588, Expect=0.0]; ENSMUSG00000024817, Uhrf2, ubiquitin-like, containing PHD and RING finger domains 2, [RH, Score=573, Expect=0.0]} {Dmel: FBgn0033636, tou, toutatis, [Score=72.0, Expect=2e-12]} {Celegans: WBGene00016200, dpff-1, Zinc finger protein dpff-1, [Score=65.1, Expect=7e-11]} {Smed: dd_Smed_v6_5428_0_1, dd_Smed_v6_5428_0_1, [Score=68.6, Expect=1e-11]} {RNA1509_16699} {RNA1310_7847, RNA1509_16699} {RNA1509_16699, RNA815_22773}
22. MligTC455_41531 265 5.52 Mlig455_024141

Neo: -

Age: Down-Up-Down

 1.739 - - 0.951 - 0.788 - Mlig455_024141 {REF} {Length: 1792} {TRANSSPLICED} {RNA1509_26233} {RNA1310_18244.1, RNA1509_26233} {RNA1509_26233, RNA815_13656.1}
23. MligTC455_52164 49 1.01 Mlig455_019248

Neo: -

Age: Down-Up-Up

Region-enriched R1: 12.972/0.02781
Region-enriched R4: 6.179/0.01048

 1.739 - - 0.984 - 0.755 - Mlig455_019248 {REF} {Length: 923} {Celegans: WBGene00015646, mlt-10, [Score=98.2, Expect=4e-23]} {RNA1509_24360} {RNA1310_75398} {RNA815_40298}
24. MligTC455_49123 58 1.21 Mlig455_057651

Neo: -

Age: -

 ASIC1 1.737 - - 0.982 - 0.755 - Mlig455_057651 {REF} {Length: 2608} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=188.4]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=71.2, Expect=3e-12]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=67.0, Expect=4e-11]} {Celegans: WBGene00012116, del-4, DEgenerin Like, [Score=89.0, Expect=3e-18]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=65.9, Expect=4e-11]} {RNA1310_10141} {RNA815_10820}
25. MligTC455_05124 30 0.63 Mlig455_013049

Neo: -

Age: -

 1.733 - - 0.984 - 0.749 - Mlig455_013049 {REF} {Length: 875} {Pfam: Lectin C-type domain [PF00059.23, score=28.5]} {RNA1509_20946} {RNA1310_85223} {RNA815_4785.4}
26. MligTC455_07208 41 0.86 Mlig455_013021

Neo: -

Age: -

 1.733 - - 0.986 - 0.747 - Mlig455_013021 {REF} {Length: 876} {Pfam: Lectin C-type domain [PF00059.23, score=28.4]} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=60.1, Expect=6e-11]} {RNA1509_20946} {RNA1310_57972} {RNA815_4785.4}
27. MligTC455_17119 145 3.03 Mlig455_027733, Mlig455_027947

Neo: -

Age: -

 PCMT1 1.73 - - 0.961 - - 0.769

Mlig455_027733 {REF} {Length: 807} {TRANSSPLICED} {Pfam: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=214.3]; Methyltransferase domain [PF13847.8, score=31.2]; Methyltransferase domain [PF13649.8, score=26.1]; tRNA methyltransferase complex GCD14 subunit [PF08704.12, score=22.7]; Methyltransferase domain [PF08241.14, score=21.0]; Methyltransferase domain [PF13679.8, score=19.7]} {Human: ENSG00000120265, PCMT1, protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=204, Expect=6e-66]} {Mouse: ENSMUSG00000116405, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]; ENSMUSG00000019795, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]} {Dmel: FBgn0086768, Pcmt, Protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=182, Expect=1e-57]} {Celegans: WBGene00003954, pcm-1, Protein-L-isoaspartate O-methyltransferase, [Score=187, Expect=1e-59]} {Smed: dd_Smed_v6_6199_0_1, dd_Smed_v6_6199_0_1, [Score=185, Expect=1e-58]} {RNA1310_30151} {RNA815_54398}

Mlig455_027947 {REF} {Length: 807} {TRANSSPLICED} {Pfam: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=214.3]; Methyltransferase domain [PF13847.8, score=31.2]; Methyltransferase domain [PF13649.8, score=26.1]; tRNA methyltransferase complex GCD14 subunit [PF08704.12, score=22.7]; Methyltransferase domain [PF08241.14, score=21.0]; Methyltransferase domain [PF13679.8, score=19.7]} {Human: ENSG00000120265, PCMT1, protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=204, Expect=6e-66]} {Mouse: ENSMUSG00000116405, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]; ENSMUSG00000019795, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=201, Expect=2e-64]} {Dmel: FBgn0086768, Pcmt, Protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=182, Expect=1e-57]} {Celegans: WBGene00003954, pcm-1, Protein-L-isoaspartate O-methyltransferase, [Score=187, Expect=1e-59]} {Smed: dd_Smed_v6_6199_0_1, dd_Smed_v6_6199_0_1, [Score=185, Expect=1e-58]} {RNA1310_30151} {RNA815_54398}
28. MligTC455_49343 537 11.19 Mlig455_020087

Neo: -

Age: Up-Down-Down

 MAP2K7 1.714 - - 0.975 - 0.739 - Mlig455_020087 {REF} {Length: 5695} {Pfam: Protein kinase domain [PF00069.27, score=173.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=128.4]; ABC1 atypical kinase-like domain [PF03109.18, score=19.3]} {Human: ENSG00000076984, MAP2K7, mitogen-activated protein kinase kinase 7, [RH, Score=346, Expect=9e-114]} {Mouse: ENSMUSG00000002948, Map2k7, mitogen-activated protein kinase kinase 7, [RH, Score=348, Expect=5e-114]; ENSMUSG00000109061, Gm49320, predicted gene, 49320, [RH, Score=346, Expect=3e-112]} {Dmel: FBgn0010303, hep, hemipterous, [RH, Score=321, Expect=4e-97]} {Celegans: WBGene00003185, mek-1, Dual specificity mitogen-activated protein kinase kinase mek-1, [RH, Score=289, Expect=7e-93]} {Smed: dd_Smed_v6_3580_0_1, dd_Smed_v6_3580_0_1, [RH, Score=327, Expect=1e-104]} {RNA1509_24359, RNA1509_30578, RNA1509_33606} {RNA1310_12988, RNA1509_24359, RNA1509_30578, RNA1509_33606} {RNA1509_24359, RNA1509_30578, RNA1509_33606, RNA815_9929}
29. MligTC455_24786 300 6.25 Mlig455_032143, Mlig455_049302

Neo: -

Age: logFC(26M/2M)=-0.528

 1.71 - - 0.966 - - 0.744

Mlig455_032143 {REF} {Length: 358} {NoTransDecoderORF} {RNA1509_36687} {RNA1310_1894} {RNA815_5614.1}

Mlig455_049302 {REF} {Length: 3378} {Pfam: PT repeat [PF04886.14, score=51.8]} {RNA1509_45844} {RNA1310_12902.2} {RNA815_515.1}
30. MligTC455_07751 326 6.79 Mlig455_017909

Neo: -

Age: logFC(26M/2M)=-0.486

 TTLL4 1.706 - - 0.966 - 0.740 - Mlig455_017909 {REF} {Length: 5319} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=290.6]; YheC/D like ATP-grasp [PF14398.8, score=24.8]} {Human: ENSG00000135912, TTLL4, tubulin tyrosine ligase like 4, [Score=501, Expect=5e-158]} {Mouse: ENSMUSG00000033257, Ttll4, tubulin tyrosine ligase-like family, member 4, [Score=516, Expect=9e-164]} {Dmel: FBgn0026147, CG16833, [Score=437, Expect=5e-138]} {Celegans: WBGene00014232, ttll-4, Tubulin polyglutamylase ttll-4, [Score=328, Expect=6e-100]} {Smed: dd_Smed_v6_17034_0_1, dd_Smed_v6_17034_0_1, [RH, Score=553, Expect=2e-178]} {RNA1509_47264, RNA1509_9319} {RNA1310_2103.1, RNA1509_47264, RNA1509_9319} {RNA1509_47264, RNA1509_9319, RNA815_5233}
31. MligTC455_17681 333 6.94 Mlig455_023232

Neo: -

Age: -

 TNS1 1.706 - - 0.974 - - 0.732 Mlig455_023232 {REF} {Length: 2927} {Pfam: SH2 domain [PF00017.26, score=42.4]} {Human: ENSG00000079308, TNS1, tensin 1, [Score=152, Expect=1e-40]; ENSG00000136205, TNS3, tensin 3, [Score=151, Expect=3e-40]; ENSG00000111077, TNS2, tensin 2, [Score=150, Expect=6e-40]} {Mouse: ENSMUSG00000055322, Tns1, tensin 1, [Score=152, Expect=6e-41]; ENSMUSG00000020422, Tns3, tensin 3, [Score=150, Expect=5e-40]; ENSMUSG00000037003, Tns2, tensin 2, [Score=147, Expect=5e-39]} {Dmel: FBgn0000244, by, blistery, [Score=143, Expect=5e-38]} {Celegans: WBGene00006508, tns-1, TeNSin homolog, [Score=136, Expect=8e-38]} {Smed: dd_Smed_v6_4494_0_2, dd_Smed_v6_4494_0_2, [Score=140, Expect=3e-37]} {RNA1509_26639} {RNA1310_9819.1, RNA1509_26639} {RNA1509_26639, RNA815_6016.1}
32. MligTC455_38930 140 2.91 Mlig455_046301, Mlig455_046979, Mlig455_047025

Neo: -

Age: Up-Up-Down

 1.705 - - 0.950 - 0.755 -

Mlig455_046301 {REF} {Length: 649} {NoTransDecoderORF} {RNA1509_25556} {RNA1310_11387.2} {RNA815_7048}

Mlig455_046979 {REF} {Length: 1372} {NoTransDecoderORF} {RNA1509_25556} {RNA1310_11387.2} {RNA815_7048}

Mlig455_047025 {REF} {Length: 5470} {RNA1509_25556} {RNA1310_11387.2, RNA1509_25556} {RNA1509_25556, RNA815_7048}
33. MligTC455_29446 56 1.17 Mlig455_061415

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=1.157

 1.703 - - 0.958 - 0.745 - Mlig455_061415 {REF} {Length: 3889} {Pfam: OB-fold nucleic acid binding domain [PF01336.27, score=48.5]; Replication protein A OB domain [PF16900.7, score=46.7]; RecG wedge domain [PF17191.6, score=18.9]} {Smed: dd_Smed_v6_3342_0_1, dd_Smed_v6_3342_0_1, [Score=89.4, Expect=2e-19]} {RNA1509_10085} {RNA1310_6627.1, RNA1509_10085} {RNA1509_10085, RNA815_3343}
34. MligTC455_49995 385 8.03 Mlig455_042998

Neo: -

Age: -

 SFXN1 1.699 - - 0.978 - - 0.721 Mlig455_042998 {REF} {Length: 2744} {TRANSSPLICED} {Pfam: Sideroflexins [PF03820.19, score=459.6]} {Human: ENSG00000164466, SFXN1, sideroflexin 1, [RH, Score=400, Expect=2e-140]; ENSG00000107819, SFXN3, sideroflexin 3, [RH, Score=396, Expect=1e-138]} {Mouse: ENSMUSG00000021474, Sfxn1, sideroflexin 1, [RH, Score=397, Expect=4e-139]; ENSMUSG00000025212, Sfxn3, sideroflexin 3, [RH, Score=396, Expect=6e-139]} {Dmel: FBgn0037239, Sfxn1-3, Sideroflexin 1/3, [RH, Score=383, Expect=6e-134]} {Celegans: WBGene00009513, sfxn-1.2, Sideroflexin, [RH, Score=320, Expect=8e-109]} {Smed: dd_Smed_v6_12292_0_1, dd_Smed_v6_12292_0_1, [RH, Score=426, Expect=6e-151]} {RNA1509_8393} {RNA1310_25049} {RNA815_11152.1}
35. MligTC455_42045 28 0.58 Mlig455_036308

Neo: -

Age: -

 1.687 - - 0.984 - 0.703 - Mlig455_036308 {REF} {Length: 2192} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=33.2]; TcdA/TcdB catalytic glycosyltransferase domain [PF12919.9, score=18.2]} {Smed: dd_Smed_v6_9783_0_1, dd_Smed_v6_9783_0_1, [Score=63.5, Expect=5e-11]} {RNA1310_143182}
36. MligTC455_17141 124 2.58 Mlig455_012668, Mlig455_030679

Neo: -

Age: -

 1.683 - - 0.977 - 0.706 -

Mlig455_012668 {REF} {Length: 1153} {Pfam: Integrase core domain [PF00665.28, score=51.1]; Integrase core domain [PF13683.8, score=24.5]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=70.5, Expect=1e-13]} {RNA1509_47734} {RNA1310_20334} {RNA815_13647}

Mlig455_030679 {REF} {Length: 2319} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.1]} {Smed: dd_Smed_v6_32358_0_1, dd_Smed_v6_32358_0_1, [Score=82.8, Expect=1e-18]} {RNA1509_47734} {RNA1310_120589} {RNA815_18785}
37. MligTC455_28543 223 4.64 Mlig455_057913

Neo: -

Age: Down-Up-Down

 TTLL6 1.677 - - 0.952 - 0.725 - Mlig455_057913 {REF} {Length: 4159} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=268.0]} {Human: ENSG00000170703, TTLL6, tubulin tyrosine ligase like 6, [RH, Score=511, Expect=3e-167]} {Mouse: ENSMUSG00000045467, Ttll13, tubulin tyrosine ligase-like family, member 13, [Score=558, Expect=0.0]} {Dmel: FBgn0039501, CG5987, [RH, Score=453, Expect=2e-147]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=220, Expect=6e-61]} {Smed: dd_Smed_v6_8131_0_1, dd_Smed_v6_8131_0_1, [Score=669, Expect=0.0]} {RNA1509_19350} {RNA1310_5550.1} {RNA815_3974}
38. MligTC455_27923 318 6.64 Mlig455_037735

Neo: -

Age: -

 1.671 - - 0.960 - - 0.711 Mlig455_037735 {REF} {Length: 2740} {Pfam: Noggin [PF05806.14, score=33.9]} {Smed: dd_Smed_v6_7999_0_1, dd_Smed_v6_7999_0_1, [Score=77.4, Expect=1e-16]} {RNA1509_58515} {RNA1310_28925, RNA1509_58515} {RNA1509_58515, RNA815_419.1}
39. MligTC455_46818 613 12.77 Mlig455_026976

Neo: -

Age: logFC(26M/2M)=-0.357

Region-enriched R4: 1.437/0.02323

 DCAF7 1.669 - - 0.956 - - 0.713 Mlig455_026976 {REF} {Length: 1597} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=34.1]} {Human: ENSG00000136485, DCAF7, DDB1 and CUL4 associated factor 7, [Score=553, Expect=0.0]} {Mouse: ENSMUSG00000049354, Dcaf7, DDB1 and CUL4 associated factor 7, [Score=553, Expect=0.0]} {Dmel: FBgn0266848, wap, wings apart, [RH, Score=555, Expect=0.0]} {Celegans: WBGene00009976, swan-2, Seven WD repeats, AN11 family, [Score=444, Expect=7e-155]} {Smed: dd_Smed_v6_3579_0_1, dd_Smed_v6_3579_0_1, [Score=507, Expect=0.0]} {RNA1509_15070, RNA1509_16437} {RNA1310_19970.1, RNA1509_15070, RNA1509_16437} {RNA1509_15070, RNA1509_16437, RNA815_9028}
40. MligTC455_25809 120 2.5 Mlig455_001845

Neo: -

Age: logFC(26M/2M)=-0.817

 0.993 - - 0.993 - - - Mlig455_001845 {REF} {Length: 3535} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=154.5]} {Smed: dd_Smed_v6_16274_0_1, dd_Smed_v6_16274_0_1, [Score=236, Expect=5e-69]} {RNA1509_16777} {RNA1310_9493} {RNA815_8118}
41. MligTC455_32959 420 8.75 Mlig455_017533, Mlig455_026822

Neo: Germline

Age: Up-Down-Down

Region-enriched R4: 2.461/0.00739

 ELF4 0.993 - - 0.993 - - -

Mlig455_017533 {REF} {Length: 4604} {Pfam: Ets-domain [PF00178.24, score=49.1]} {Human: ENSG00000102034, ELF4, E74 like ETS transcription factor 4, [Score=59.3, Expect=3e-08]; ENSG00000109381, ELF2, E74 like ETS transcription factor 2, [Score=57.4, Expect=1e-07]} {Mouse: ENSMUSG00000037174, Elf2, E74-like factor 2, [Score=61.6, Expect=5e-09]} {Smed: dd_Smed_v6_7247_0_1, dd_Smed_v6_7247_0_1, [RH, Score=68.9, Expect=2e-12]} {RNA1509_17091, RNA1509_29830} {RNA1310_1652, RNA1509_29830} {RNA1509_29830, RNA815_1367}

Mlig455_026822 {REF} {Length: 4556} {Pfam: Ets-domain [PF00178.24, score=49.2]} {Human: ENSG00000102034, ELF4, E74 like ETS transcription factor 4, [Score=59.3, Expect=3e-08]; ENSG00000109381, ELF2, E74 like ETS transcription factor 2, [Score=57.0, Expect=1e-07]} {Mouse: ENSMUSG00000037174, Elf2, E74-like factor 2, [Score=61.2, Expect=5e-09]} {Smed: dd_Smed_v6_7247_0_1, dd_Smed_v6_7247_0_1, [RH, Score=68.9, Expect=2e-12]} {RNA1509_17091, RNA1509_59324} {RNA1310_1652, RNA1509_17091, RNA1509_59324} {RNA1509_17091, RNA1509_59324, RNA815_1367}
42. MligTC455_41437 452 9.42 Mlig455_017634

Neo: -

Age: Down-Up-Up

 WDR46 0.993 - - 0.993 - - - Mlig455_017634 {REF} {Length: 2872} {Pfam: BING4CT (NUC141) domain [PF08149.13, score=80.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=21.0]} {Human: ENSG00000226916, WDR46, WD repeat domain 46, [Score=243, Expect=2e-70]; ENSG00000204221, WDR46, WD repeat domain 46, [Score=243, Expect=2e-70]; ENSG00000236222, WDR46, WD repeat domain 46, [Score=243, Expect=2e-70]; ENSG00000227057, WDR46, WD repeat domain 46, [Score=243, Expect=1e-70]; ENSG00000206284, WDR46, WD repeat domain 46, [Score=242, Expect=5e-70]} {Mouse: ENSMUSG00000024312, Wdr46, WD repeat domain 46, [Score=244, Expect=7e-71]} {Dmel: FBgn0030000, CG2260, [Score=251, Expect=8e-74]} {Celegans: WBGene00009211, wdr-46, WD Repeat protein, [Score=245, Expect=6e-72]} {Smed: dd_Smed_v6_10180_0_1, dd_Smed_v6_10180_0_1, [RH, Score=236, Expect=4e-69]} {RNA1509_5871} {RNA1310_17370} {RNA815_4556}
43. MligTC455_28413 107 2.22 Mlig455_032935

Neo: -

Age: -

 0.992 - - 0.992 - - - Mlig455_032935 {REF} {Length: 3941} {RNA1509_15744} {RNA1310_6945.1} {RNA815_14623.1}
44. MligTC455_32703 120 2.5 Mlig455_041954

Neo: -

Age: Down-Down-Up

 HTATIP2 0.992 - - 0.992 - - - Mlig455_041954 {REF} {Length: 1425} {TRANSSPLICED} {Pfam: NAD(P)H-binding [PF13460.8, score=36.0]; Semialdehyde dehydrogenase, NAD binding domain [PF01118.26, score=23.1]} {Human: ENSG00000109854, HTATIP2, HIV-1 Tat interactive protein 2, [RH, Score=175, Expect=4e-54]} {Mouse: ENSMUSG00000039745, Htatip2, HIV-1 Tat interactive protein 2, [RH, Score=178, Expect=2e-55]} {Celegans: WBGene00050941, C33F10.14, [RH, Score=179, Expect=2e-56]} {Smed: dd_Smed_v6_342_0_1, dd_Smed_v6_342_0_1, [RH, Score=206, Expect=6e-67]} {RNA1509_45742} {RNA1310_24342.1, RNA1509_45742} {RNA1509_45742, RNA815_17118}
45. MligTC455_26366 75 1.56 Mlig455_013893

Neo: -

Age: -

 NSUN7 0.991 - - 0.991 - - - Mlig455_013893 {REF} {Length: 1904} {Human: ENSG00000179299, NSUN7, NOP2/Sun RNA methyltransferase family member 7, [Score=167, Expect=4e-45]} {Mouse: ENSMUSG00000029206, Nsun7, NOL1/NOP2/Sun domain family, member 7, [Score=164, Expect=3e-44]} {Dmel: FBgn0266099, CG44836, [Score=72.8, Expect=2e-13]} {Celegans: WBGene00013151, nsun-5, Nop2 (NOP2)/SUN domain family member, [Score=56.2, Expect=2e-08]} {Smed: dd_Smed_v6_30093_0_1, dd_Smed_v6_30093_0_1, [Score=203, Expect=3e-60]} {RNA1310_17601} {RNA815_32144}
46. MligTC455_33432 59 1.23 Mlig455_047130, Mlig455_049075

Neo: -

Age: -

 0.991 - - 0.991 - - -

Mlig455_047130 {REF} {Length: 683} {Pfam: Protein of unknown function (FYDLN_acid) [PF09538.12, score=19.5]} {RNA1509_52826} {RNA1310_267.1} {RNA815_381.1}

Mlig455_049075 {REF} {Length: 2317} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=34.7]} {RNA1509_13203} {RNA1310_267.2} {RNA815_381.1}
47. MligTC455_36765 37 0.78 Mlig455_060967

Neo: -

Age: -

 0.991 - - 0.991 - - - Mlig455_060967 {REF} {Length: 6411} {Pfam: Protein of unknown function (DUF1759) [PF03564.17, score=61.4]} {Smed: dd_Smed_v6_10245_0_1, dd_Smed_v6_10245_0_1, [RH, Score=63.5, Expect=9e-13]} {RNA1509_55800} {RNA1310_1066} {RNA815_13195}
48. MligTC455_21223 119 2.48 Mlig455_004040, Mlig455_046131, Mlig455_052135

Neo: -

Age: -

 0.99 - - 0.990 - - -

Mlig455_004040 {REF} {Length: 629} {RNA1509_45210} {RNA1310_81175} {RNA815_45657}

Mlig455_046131 {REF} {Length: 309} {RNA1509_45210} {RNA1310_48584} {RNA815_45657}

Mlig455_052135 {REF} {Length: 1085} {RNA1509_58333} {RNA1310_55385.1} {RNA815_38567}
49. MligTC455_53151 232 4.83 Mlig455_057764, Mlig455_070304

Neo: -

Age: -

 0.99 - - 0.990 - - -

Mlig455_057764 {REF} {Length: 1905} {TRANSSPLICED} {RNA1509_20954} {RNA1310_9776.1} {RNA815_6133.1}

Mlig455_070304 {REF} {Length: 1842} {TRANSSPLICED} {RNA1509_20954} {RNA1310_9776.1, RNA1509_20954} {RNA1509_20954, RNA815_6133.1}
50. MligTC455_09217 91 1.9 Mlig455_060351

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.340

 0.989 - - 0.989 - - - Mlig455_060351 {REF} {Length: 3413} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=125.1]} {Smed: dd_Smed_v6_22997_0_1, dd_Smed_v6_22997_0_1, [Score=55.1, Expect=7e-08]} {RNA1509_20377} {RNA1310_5914, RNA1509_20377} {RNA1509_20377, RNA815_9968}
51. MligTC455_21222 221 4.6 Mlig455_038486, Mlig455_046701, Mlig455_052136, Mlig455_055634

Neo: -

Age: -

Region-enriched R1: 7.823/0.00076
Region-enriched R4: 5.534/0.00000

 0.989 - - 0.989 - - -

Mlig455_038486 {REF} {Length: 1089} {RNA1509_55040} {RNA1310_81175} {RNA815_45657}

Mlig455_046701 {REF} {Length: 758} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_81175} {RNA815_45657}

Mlig455_052136 {REF} {Length: 296} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_48584} {RNA815_45657}

Mlig455_055634 {REF} {Length: 254} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_81175} {RNA815_45657}
52. MligTC455_23249 141 2.94 Mlig455_004995, Mlig455_005280

Neo: Int S/G2/M

Age: Down-Up-Down

Region-enriched R4: 2.920/0.00384

 0.989 - - 0.989 - - -

Mlig455_004995 {REF} {Length: 3886} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=150.8]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=57.0, Expect=2e-08]} {RNA1509_47799} {RNA1310_5746.1, RNA1509_47799} {RNA1509_47799, RNA815_13564}

Mlig455_005280 {REF} {Length: 5002} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=151.1]} {Smed: dd_Smed_v6_21491_0_1, dd_Smed_v6_21491_0_1, [Score=56.6, Expect=3e-08]} {RNA1509_47799} {RNA1310_5746.1} {RNA815_13564}
53. MligTC455_27933 109 2.27 Mlig455_062805

Neo: -

Age: logFC(26M/2M)=0.852

 MYLK 0.989 - - 0.989 - - - Mlig455_062805 {REF} {Length: 5619} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=190.4]; Protein kinase domain [PF00069.27, score=143.5]; Immunoglobulin domain [PF13927.8, score=121.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=80.8]; Immunoglobulin domain [PF13895.8, score=52.2]; Immunoglobulin domain [PF00047.27, score=51.8]; Immunoglobulin V-set domain [PF07686.19, score=38.3]; ABC1 atypical kinase-like domain [PF03109.18, score=21.5]} {Human: ENSG00000065534, MYLK, myosin light chain kinase, [Score=184, Expect=7e-47]; ENSG00000140795, MYLK3, myosin light chain kinase 3, [Score=176, Expect=6e-45]} {Mouse: ENSMUSG00000051747, Ttn, titin, [Score=187, Expect=6e-48]; ENSMUSG00000022836, Mylk, myosin, light polypeptide kinase, [Score=184, Expect=4e-47]} {Dmel: FBgn0005666, bt, bent, [Score=197, Expect=4e-51]} {Celegans: WBGene00006759, unc-22, Twitchin, [Score=216, Expect=1e-57]} {Smed: dd_Smed_v6_2544_0_1, dd_Smed_v6_2544_0_1, [Score=184, Expect=2e-47]} {RNA1509_411} {RNA1310_1.1} {RNA815_0}
54. MligTC455_39359 856 17.84 Mlig455_043733, Mlig455_043824

Neo: Irradiation

Age: -

 HEATR1 0.989 - - 0.989 - - -

Mlig455_043733 {REF} {Length: 6084} {TRANSSPLICED} {Pfam: U3 small nucleolar RNA-associated protein 10 [PF12397.10, score=23.7]} {Human: ENSG00000119285, HEATR1, HEAT repeat containing 1, [Score=103, Expect=2e-21]} {Mouse: ENSMUSG00000050244, Heatr1, HEAT repeat containing 1, [RH, Score=90.9, Expect=7e-18]} {RNA1509_12757, RNA1509_2547} {RNA1310_1787.1, RNA1509_12757, RNA1509_2547} {RNA1509_12757, RNA1509_2547, RNA815_4052}

Mlig455_043824 {REF} {Length: 6006} {TRANSSPLICED} {Pfam: U3 small nucleolar RNA-associated protein 10 [PF12397.10, score=23.7]} {Human: ENSG00000119285, HEATR1, HEAT repeat containing 1, [Score=104, Expect=1e-21]} {Mouse: ENSMUSG00000050244, Heatr1, HEAT repeat containing 1, [RH, Score=92.8, Expect=2e-18]} {RNA1509_2547} {RNA1310_1787.1} {RNA815_4052}
55. MligTC455_39360 427 8.9 Mlig455_047425

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.530

 HEATR1 0.989 - - 0.989 - - - Mlig455_047425 {REF} {Length: 6031} {TRANSSPLICED} {Pfam: U3 small nucleolar RNA-associated protein 10 [PF12397.10, score=23.7]} {Human: ENSG00000119285, HEATR1, HEAT repeat containing 1, [Score=103, Expect=2e-21]} {Mouse: ENSMUSG00000050244, Heatr1, HEAT repeat containing 1, [RH, Score=91.7, Expect=4e-18]} {RNA1509_2547, RNA1509_58129} {RNA1310_1787.1, RNA1509_58129} {RNA1509_58129, RNA815_4052}
56. MligTC455_46820 262 5.46 Mlig455_027121

Neo: -

Age: logFC(26M/2M)=0.725

 DCAF7 0.989 - - 0.989 - - - Mlig455_027121 {REF} {Length: 1601} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=34.0]} {Human: ENSG00000136485, DCAF7, DDB1 and CUL4 associated factor 7, [Score=551, Expect=0.0]} {Mouse: ENSMUSG00000049354, Dcaf7, DDB1 and CUL4 associated factor 7, [Score=551, Expect=0.0]} {Dmel: FBgn0266848, wap, wings apart, [RH, Score=553, Expect=0.0]} {Celegans: WBGene00009976, swan-2, Seven WD repeats, AN11 family, [Score=443, Expect=2e-154]} {Smed: dd_Smed_v6_3579_0_1, dd_Smed_v6_3579_0_1, [Score=504, Expect=2e-180]} {RNA1509_16437} {RNA1310_19970.1} {RNA815_9028}
57. MligTC455_13613 133 2.77 Mlig455_047175, Mlig455_048504

Neo: Germline

Age: Up-Down-Down

 0.988 - - 0.988 - - -

Mlig455_047175 {REF} {Length: 967} {RNA1310_43089} {RNA815_23666}

Mlig455_048504 {REF} {Length: 949} {RNA1310_43089} {RNA815_23666}
58. MligTC455_30381 280 5.84 Mlig455_029588

Neo: -

Age: -

 TRAF6 0.988 - - 0.988 - - - Mlig455_029588 {REF} {Length: 2041} {Pfam: TRAF-type zinc finger [PF02176.20, score=39.9]} {Human: ENSG00000175104, TRAF6, TNF receptor associated factor 6, [Score=90.1, Expect=6e-19]; ENSG00000131323, TRAF3, TNF receptor associated factor 3, [Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000021277, Traf3, TNF receptor-associated factor 3, [Score=93.2, Expect=4e-20]} {Smed: dd_Smed_v6_168_0_1, dd_Smed_v6_168_0_1, [Score=91.7, Expect=4e-20]} {RNA1509_16871} {RNA1310_25901} {RNA815_11260}
59. MligTC455_31588 68 1.42 Mlig455_061297

Neo: -

Age: -

 METTL26 0.988 - - 0.988 - - - Mlig455_061297 {REF} {Length: 1314} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF938) [PF06080.14, score=196.0]} {Human: ENSG00000130731, METTL26, methyltransferase like 26, [RH, Score=159, Expect=6e-49]} {Mouse: ENSMUSG00000025731, Mettl26, methyltransferase like 26, [RH, Score=174, Expect=1e-54]} {Dmel: FBgn0040964, CG18661, [RH, Score=136, Expect=4e-40]} {Celegans: WBGene00012514, Y26E6A.3, [RH, Score=136, Expect=3e-40]} {RNA1509_3605} {RNA1310_37044} {RNA815_17772}
60. MligTC455_33674 265 5.53 Mlig455_053685

Neo: -

Age: Down-Up-Up

Regeneration-upregulated R2: 3.790

Regeneration-enriched R2: 3.790

 0.988 - - 0.988 - - - Mlig455_053685 {REF} {Length: 2654} {Pfam: Translocon-associated protein (TRAP), alpha subunit [PF03896.18, score=18.7]} {RNA1509_8786} {RNA1310_54930} {RNA815_14838.2}
61. MligTC455_41257 56 1.16 Mlig455_056117

Neo: -

Age: -

 0.988 - - 0.988 - - - Mlig455_056117 {REF} {Length: 2005} {NoTransDecoderORF} {RNA1509_48737} {RNA1310_117806} {RNA815_57504}
62. MligTC455_44689 194 4.05 Mlig455_048802

Neo: -

Age: -

 NKRF 0.988 - - 0.988 - - - Mlig455_048802 {REF} {Length: 3088} {TRANSSPLICED} {Pfam: XRN-Two Binding Domain, XTBD [PF11952.10, score=48.3]; G-patch domain [PF01585.25, score=30.8]; G-patch domain [PF12656.9, score=30.8]; R3H domain [PF01424.24, score=23.8]} {Human: ENSG00000186416, NKRF, NFKB repressing factor, [RH, Score=79.0, Expect=7e-15]} {Mouse: ENSMUSG00000044149, Nkrf, NF-kappaB repressing factor, [RH, Score=80.5, Expect=1e-15]} {Celegans: WBGene00013224, Y55D9A.2, [Score=49.7, Expect=3e-06]} {Smed: dd_Smed_v6_10443_0_1, dd_Smed_v6_10443_0_1, [RH, Score=95.9, Expect=5e-21]} {RNA1509_22309} {RNA1310_17483.1, RNA1509_22309} {RNA1509_22309, RNA815_7028}
63. MligTC455_22450 40 0.83 Mlig455_024092, Mlig455_033065

Neo: -

Age: -

 ASIC2, ASIC3 0.987 - - 0.987 - - -

Mlig455_024092 {REF} {Length: 1894} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=190.8]} {Human: ENSG00000213199, ASIC3, acid sensing ion channel subunit 3, [Score=58.5, Expect=2e-08]; ENSG00000108684, ASIC2, acid sensing ion channel subunit 2, [Score=57.4, Expect=5e-08]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [Score=56.2, Expect=8e-08]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=54.7, Expect=2e-07]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=107, Expect=4e-24]} {RNA1310_43687}

Mlig455_033065 {REF} {Length: 2669} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=192.0]} {Human: ENSG00000108684, ASIC2, acid sensing ion channel subunit 2, [Score=60.8, Expect=5e-09]} {Mouse: ENSMUSG00000020704, Asic2, acid-sensing (proton-gated) ion channel 2, [Score=56.2, Expect=8e-08]; ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=54.7, Expect=2e-07]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=108, Expect=1e-24]} {RNA1310_43687}
64. MligTC455_48964 1805 37.6 Mlig455_032203, Mlig455_054201, Mlig455_060743

Neo: Int S/G2/M

Age: -

 HDGFL2 0.987 - - 0.987 - - -

Mlig455_032203 {REF} {Length: 3949} {TRANSSPLICED} {Pfam: Lens epithelium-derived growth factor (LEDGF) [PF11467.10, score=54.1]; PWWP domain [PF00855.19, score=35.7]} {Human: ENSG00000167674, HDGFL2, HDGF like 2, [RH, Score=109, Expect=5e-24]; ENSG00000166503, HDGFL3, HDGF like 3, [RH, Score=108, Expect=4e-26]; ENSG00000164985, PSIP1, PC4 and SFRS1 interacting protein 1, [RH, Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000002833, Hdgfl2, HDGF like 2, [RH, Score=109, Expect=4e-24]; ENSMUSG00000025104, Hdgfl3, HDGF like 3, [RH, Score=107, Expect=4e-26]; ENSMUSG00000028484, Psip1, PC4 and SFRS1 interacting protein 1, [RH, Score=106, Expect=2e-23]} {Dmel: FBgn0039743, CG7946, [RH, Score=53.1, Expect=7e-07]} {Smed: dd_Smed_v6_2842_0_3, dd_Smed_v6_2842_0_3, [RH, Score=144, Expect=4e-35]} {RNA1509_10931, RNA1509_22006} {RNA1310_2576.1, RNA1509_10931} {RNA1509_10931, RNA815_1028.1}

Mlig455_054201 {REF} {Length: 3958} {TRANSSPLICED} {Pfam: Lens epithelium-derived growth factor (LEDGF) [PF11467.10, score=54.1]; PWWP domain [PF00855.19, score=35.7]} {Human: ENSG00000167674, HDGFL2, HDGF like 2, [RH, Score=109, Expect=5e-24]; ENSG00000166503, HDGFL3, HDGF like 3, [RH, Score=108, Expect=3e-26]; ENSG00000164985, PSIP1, PC4 and SFRS1 interacting protein 1, [RH, Score=106, Expect=2e-23]} {Mouse: ENSMUSG00000002833, Hdgfl2, HDGF like 2, [RH, Score=109, Expect=3e-24]; ENSMUSG00000025104, Hdgfl3, HDGF like 3, [RH, Score=107, Expect=4e-26]; ENSMUSG00000028484, Psip1, PC4 and SFRS1 interacting protein 1, [RH, Score=106, Expect=2e-23]} {Dmel: FBgn0039743, CG7946, [RH, Score=53.1, Expect=7e-07]} {Smed: dd_Smed_v6_2842_0_3, dd_Smed_v6_2842_0_3, [RH, Score=144, Expect=4e-35]} {RNA1509_22006} {RNA1310_2576.1, RNA1509_22006} {RNA1509_22006, RNA815_1028.1}

Mlig455_060743 {REF} {Length: 3625} {TRANSSPLICED} {Pfam: Lens epithelium-derived growth factor (LEDGF) [PF11467.10, score=54.3]} {Mouse: ENSMUSG00000028484, Psip1, PC4 and SFRS1 interacting protein 1, [Score=49.7, Expect=1e-05]} {Smed: dd_Smed_v6_2842_0_4, dd_Smed_v6_2842_0_4, [Score=84.0, Expect=2e-16]} {RNA1509_22006, RNA1509_42178} {RNA1310_2576.1, RNA1509_42178} {RNA1509_42178, RNA815_1028.1}
65. MligTC455_49651 88 1.84 Mlig455_057435

Neo: -

Age: -

 0.987 - - 0.987 - - - Mlig455_057435 {REF} {Length: 1917} {Pfam: Globin [PF00042.24, score=35.4]} {RNA1509_44858} {RNA1310_41214} {RNA815_18425}
66. MligTC455_50156 379 7.9 Mlig455_061886

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.454

Regeneration-upregulated BL: 2.171

Regeneration-enriched BL: 2.171

 BEST2 0.987 - - 0.987 - - - Mlig455_061886 {REF} {Length: 2189} {Pfam: Bestrophin, RFP-TM, chloride channel [PF01062.23, score=157.1]} {Human: ENSG00000039987, BEST2, bestrophin 2, [Score=102, Expect=2e-22]} {Mouse: ENSMUSG00000052819, Best2, bestrophin 2, [Score=102, Expect=5e-23]} {Dmel: FBgn0040238, Best1, Bestrophin 1, [Score=181, Expect=1e-49]} {Celegans: WBGene00014989, best-23, Bestrophin homolog, [Score=144, Expect=3e-38]} {Smed: dd_Smed_v6_3859_0_1, dd_Smed_v6_3859_0_1, [Score=233, Expect=5e-71]} {RNA1509_12991, RNA1509_40942} {RNA1310_14129.1, RNA1509_12991, RNA1509_40942} {RNA1509_12991, RNA1509_40942, RNA815_5240}
67. MligTC455_18527 360 7.5 Mlig455_012969, Mlig455_028760, Mlig455_033181, Mlig455_046334

Neo: -

Age: -

 0.986 - - 0.986 - - -

Mlig455_012969 {REF} {Length: 8607} {TRANSSPLICED} {Pfam: Sarcoglycan complex subunit protein [PF04790.15, score=23.1]; U11-48K-like CHHC zinc finger [PF05253.14, score=21.1]} {RNA1509_4266} {RNA1310_7216} {RNA815_4504}

Mlig455_028760 {REF} {Length: 4445} {TRANSSPLICED} {Pfam: Sarcoglycan complex subunit protein [PF04790.15, score=23.1]; U11-48K-like CHHC zinc finger [PF05253.14, score=21.1]} {RNA1509_4266} {RNA1310_7216} {RNA815_4504}

Mlig455_033181 {REF} {Length: 5163} {TRANSSPLICED} {Pfam: Sarcoglycan complex subunit protein [PF04790.15, score=23.1]; U11-48K-like CHHC zinc finger [PF05253.14, score=21.1]} {RNA1509_4266} {RNA1310_7216} {RNA815_4504}

Mlig455_046334 {REF} {Length: 4445} {TRANSSPLICED} {Pfam: Sarcoglycan complex subunit protein [PF04790.15, score=23.1]; U11-48K-like CHHC zinc finger [PF05253.14, score=21.1]} {RNA1509_4266} {RNA1310_7216} {RNA815_4504}
68. MligTC455_29252 178 3.71 Mlig455_065715

Neo: -

Age: -

Region-enriched R3: 2.865/0.04022

 0.986 - - 0.986 - - - Mlig455_065715 {REF} {Length: 5250} {Pfam: Phage integrase family [PF00589.24, score=23.8]} {RNA1509_28547} {RNA1310_7494.1} {RNA815_21377}
69. MligTC455_29269 82 1.71 Mlig455_066940, Mlig455_070362

Neo: -

Age: -

 0.986 - - 0.986 - - -

Mlig455_066940 {REF} {Length: 1055} {NoTransDecoderORF} {RNA1509_25022} {RNA1310_102339} {RNA815_4278}

Mlig455_070362 {REF} {Length: 1537} {NoTransDecoderORF} {RNA1509_2860} {RNA1310_11421.1} {RNA815_19691.1}
70. MligTC455_31485 214 4.45 Mlig455_069811

Neo: -

Age: logFC(26M/2M)=-0.319

 XIAP 0.986 - - 0.986 - - - Mlig455_069811 {REF} {Length: 3934} {Pfam: Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=40.2]; Inhibitor of Apoptosis domain [PF00653.23, score=36.8]; Prokaryotic RING finger family 4 [PF14447.8, score=20.3]} {Human: ENSG00000101966, XIAP, X-linked inhibitor of apoptosis, [Score=78.6, Expect=9e-15]} {Mouse: ENSMUSG00000025860, Xiap, X-linked inhibitor of apoptosis, [Score=77.0, Expect=2e-14]} {Dmel: FBgn0015247, Diap2, Death-associated inhibitor of apoptosis 2, [Score=90.9, Expect=6e-19]} {Smed: dd_Smed_v6_4626_0_1, dd_Smed_v6_4626_0_1, [Score=62.0, Expect=4e-10]} {RNA1509_28705, RNA1509_50002} {RNA1310_7949.1, RNA1509_28705, RNA1509_50002} {RNA1509_28705, RNA1509_50002, RNA815_4630}
71. MligTC455_32078 88 1.83 Mlig455_059989

Neo: -

Age: Up-Down-Down

 SSTR4 0.986 - - 0.986 - - - Mlig455_059989 {REF} {Length: 7870} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=55.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=20.5]} {Human: ENSG00000132671, SSTR4, somatostatin receptor 4, [Score=55.8, Expect=1e-07]} {Mouse: ENSMUSG00000037014, Sstr4, somatostatin receptor 4, [Score=57.0, Expect=3e-08]} {RNA1509_17715} {RNA1310_22369} {RNA815_5685.1}
72. MligTC455_38704 289 6.03 Mlig455_058635

Neo: -

Age: -

 PSMC1 0.986 - - 0.986 - - - Mlig455_058635 {REF} {Length: 2118} {TRANSSPLICED} {Pfam: Conserved hypothetical ATP binding protein [PF03029.19, score=200.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=141.5]; Proteasomal ATPase OB C-terminal domain [PF16450.7, score=40.0]; AAA domain (Cdc48 subfamily) [PF07724.16, score=26.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=24.3]; AAA+ lid domain [PF17862.3, score=23.7]; Protein of unknown function (DUF815) [PF05673.15, score=23.5]; AAA domain [PF13401.8, score=23.5]; AAA domain [PF13238.8, score=23.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=22.0]; Ferrous iron transport protein B [PF02421.20, score=20.8]; AAA ATPase domain [PF13191.8, score=20.2]} {Human: ENSG00000100764, PSMC1, proteasome 26S subunit, ATPase 1, [Score=561, Expect=0.0]} {Mouse: ENSMUSG00000021178, Psmc1, protease (prosome, macropain) 26S subunit, ATPase 1, [Score=561, Expect=0.0]} {Dmel: FBgn0015282, Rpt2, Regulatory particle triple-A ATPase 2, [Score=568, Expect=0.0]} {Celegans: WBGene00004502, rpt-2, Probable 26S protease regulatory subunit 4, [Score=549, Expect=0.0]} {Smed: dd_Smed_v6_1222_0_1, dd_Smed_v6_1222_0_1, [Score=574, Expect=0.0]} {RNA1509_1201} {RNA1310_10914} {RNA815_3274.2}
73. MligTC455_39081 135 2.81 Mlig455_046917

Neo: Int S/G2/M

Age: -

Region-enriched R4: 4.814/0.00608

 MRE11 0.986 - - 0.986 - - - Mlig455_046917 {REF} {Length: 5274} {TRANSSPLICED} {Pfam: Mre11 DNA-binding presumed domain [PF04152.16, score=118.3]; Calcineurin-like phosphoesterase [PF00149.30, score=50.0]; Calcineurin-like phosphoesterase superfamily domain [PF12850.9, score=22.2]} {Human: ENSG00000020922, MRE11, MRE11 homolog, double strand break repair nuclease, [RH, Score=492, Expect=7e-165]} {Mouse: ENSMUSG00000031928, Mre11a, MRE11A homolog A, double strand break repair nuclease, [RH, Score=485, Expect=3e-162]} {Dmel: FBgn0020270, mre11, meiotic recombination 11, [RH, Score=362, Expect=8e-116]} {Celegans: WBGene00003405, mre-11, Double-strand break repair protein mre-11, [RH, Score=349, Expect=7e-110]} {Smed: dd_Smed_v6_4961_0_1, dd_Smed_v6_4961_0_1, [RH, Score=432, Expect=3e-143]} {RNA1509_23285, RNA1509_59039} {RNA1310_7622.1, RNA1509_23285, RNA1509_59039} {RNA1509_23285, RNA1509_59039, RNA815_13142}
74. MligTC455_16524 661 13.77 Mlig455_050300

Neo: -

Age: logFC(26M/2M)=-0.581

Region-enriched R3: 2.041/0.01248

 0.985 - - 0.985 - - - Mlig455_050300 {REF} {Length: 1403} {RNA1509_35673, RNA1509_45798, RNA1509_5988} {RNA1310_23775, RNA1509_35673, RNA1509_45798, RNA1509_5988} {RNA1509_35673, RNA1509_45798, RNA1509_5988, RNA815_15000.1}
75. MligTC455_21062 115 2.39 Mlig455_023244, Mlig455_026561, Mlig455_027394, Mlig455_028022, Mlig455_066349, Mlig455_067765

Neo: -

Age: -

 0.985 - - 0.985 - - -

Mlig455_023244 {REF} {Length: 4156} {RNA1509_51835} {RNA1310_29742} {RNA815_15908}

Mlig455_026561 {REF} {Length: 871} {RNA1509_51835} {RNA1310_29742} {RNA815_15908}

Mlig455_027394 {REF} {Length: 609} {RNA1509_51835} {RNA1310_99393} {RNA815_15908}

Mlig455_028022 {REF} {Length: 655} {TRANSSPLICED} {RNA1509_51835} {RNA1310_26578.1} {RNA815_15908}

Mlig455_066349 {REF} {Length: 2048} {RNA1509_51835} {RNA1310_47469} {RNA815_14090.1}

Mlig455_067765 {REF} {Length: 659} {Pfam: Phage integrase family [PF00589.24, score=40.6]} {RNA1509_34535} {RNA1310_33735.1} {RNA815_39170}
76. MligTC455_25810 160 3.34 Mlig455_007369

Neo: -

Age: logFC(26M/2M)=-0.475

 0.985 - - 0.985 - - - Mlig455_007369 {REF} {Length: 1460} {Pfam: Glycosyltransferase family 92 [PF01697.29, score=112.7]; Glycosyl transferase family 2 [PF13704.8, score=24.3]} {Celegans: WBGene00012941, Y47D3B.4, [Score=53.1, Expect=3e-07]} {Smed: dd_Smed_v6_5401_0_1, dd_Smed_v6_5401_0_1, [Score=197, Expect=4e-58]} {RNA1310_16379.1} {RNA815_14941.1}
77. MligTC455_28780 110 2.3 Mlig455_054223

Neo: -

Age: Up-Down-Up

 TANC2 0.985 - - 0.985 - - - Mlig455_054223 {REF} {Length: 4977} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=48.3]; Mab-21 protein [PF03281.16, score=44.1]; Ankyrin repeats (3 copies) [PF12796.9, score=42.1]; Ankyrin repeats (many copies) [PF13857.8, score=37.1]; Ankyrin repeat [PF13606.8, score=34.3]; Ankyrin repeat [PF00023.32, score=33.2]} {Human: ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=68.6, Expect=6e-11]} {Mouse: ENSMUSG00000053580, Tanc2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=68.6, Expect=4e-11]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=68.6, Expect=2e-11]} {Celegans: WBGene00011240, R11A8.7, Ankyrin repeat and KH domain-containing protein R11A8.7, [Score=61.6, Expect=3e-09]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=57.8, Expect=3e-08]} {RNA1509_27730} {RNA1310_4721} {RNA815_5358.1}
78. MligTC455_33433 512 10.66 Mlig455_007084, Mlig455_015087, Mlig455_027876, Mlig455_033676, Mlig455_041557, Mlig455_044268, Mlig455_048656, Mlig455_058403, Mlig455_063235, Mlig455_068131

Neo: -

Age: Up-Down-Down

 0.985 - - 0.985 - - -

Mlig455_007084 {REF} {Length: 2774} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=33.2]} {RNA1509_13203} {RNA1310_267.2} {RNA815_381.1}

Mlig455_015087 {REF} {Length: 2505} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=34.7]} {RNA1509_13203} {RNA1310_267.2} {RNA815_381.1}

Mlig455_027876 {REF} {Length: 776} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=34.7]} {RNA1509_13203} {RNA1310_267.1} {RNA815_381.1}

Mlig455_033676 {REF} {Length: 917} {RNA1509_52826} {RNA1310_267.2} {RNA815_381.1}

Mlig455_041557 {REF} {Length: 916} {RNA1509_13203} {RNA1310_267.2} {RNA815_381.1}

Mlig455_044268 {REF} {Length: 928} {TRANSSPLICED} {RNA1509_13203} {RNA1310_267.2} {RNA815_381.1}

Mlig455_048656 {REF} {Length: 773} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=34.7]} {RNA1509_52826} {RNA1310_267.2} {RNA815_381.1}

Mlig455_058403 {REF} {Length: 776} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=34.7]} {RNA1509_13203} {RNA1310_267.1} {RNA815_381.1}

Mlig455_063235 {REF} {Length: 1007} {TRANSSPLICED} {RNA1509_13203} {RNA1310_267.2} {RNA815_381.1}

Mlig455_068131 {REF} {Length: 1340} {Pfam: Transcriptional Coactivator p15 (PC4) [PF02229.18, score=35.4]} {RNA1509_52826} {RNA1310_267.2} {RNA815_381.1}
79. MligTC455_40428 47 0.98 Mlig455_017180

Neo: Irradiation

Age: -

Region-enriched R4: 5.668/0.00000

 0.985 - - 0.985 - - - Mlig455_017180 {REF} {Length: 3254} {RNA1509_22767, RNA1509_52352} {RNA1310_22898.1, RNA1509_22767} {RNA1509_22767, RNA815_40500}
80. MligTC455_40863 70 1.46 Mlig455_014267

Neo: -

Age: Up-Down-Down

 PCDH1 0.985 - - 0.985 - - - Mlig455_014267 {REF} {Length: 5379} {Pfam: Cadherin domain [PF00028.19, score=328.1]; Cadherin-like [PF16184.7, score=31.3]; Cadherin-like [PF08266.14, score=29.2]} {Human: ENSG00000156453, PCDH1, protocadherin 1, [RH, Score=298, Expect=2e-84]} {Mouse: ENSMUSG00000051375, Pcdh1, protocadherin 1, [RH, Score=300, Expect=3e-85]} {Dmel: FBgn0284247, ds, dachsous, [Score=269, Expect=2e-73]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=197, Expect=6e-51]} {Smed: dd_Smed_v6_14117_0_1, dd_Smed_v6_14117_0_1, [Score=404, Expect=8e-123]} {RNA1310_32856} {RNA815_39004}
81. MligTC455_41834 200 4.17 Mlig455_027375

Neo: -

Age: logFC(26M/2M)=-0.372

 CC2D2A 0.985 - - 0.985 - - - Mlig455_027375 {REF} {Length: 5957} {TRANSSPLICED} {Pfam: CC2D2A N-terminal C2 domain [PF15625.8, score=70.6]; Family of unknown function (DUF5523) [PF17661.3, score=35.0]; C2 domain [PF00168.32, score=22.3]} {Human: ENSG00000048342, CC2D2A, coiled-coil and C2 domain containing 2A, [RH, Score=370, Expect=2e-104]} {Mouse: ENSMUSG00000039765, Cc2d2a, coiled-coil and C2 domain containing 2A, [Score=358, Expect=1e-100]} {Smed: dd_Smed_v6_11189_0_1, dd_Smed_v6_11189_0_1, [RH, Score=442, Expect=2e-129]} {RNA1509_7543} {RNA1310_1060.1} {RNA815_605.1}
82. MligTC455_42413 82 1.7 Mlig455_010342

Neo: -

Age: -

 0.985 - - 0.985 - - - Mlig455_010342 {REF} {Length: 3709} {RNA1509_29028} {RNA1310_28194.1} {RNA815_10475.1}
83. MligTC455_50322 253 5.26 Mlig455_007808, Mlig455_021090

Neo: -

Age: -

 KDM4A 0.985 - - 0.985 - - -

Mlig455_007808 {REF} {Length: 2597} {TRANSSPLICED} {Pfam: JmjC domain, hydroxylase [PF02373.24, score=142.3]; jmjN domain [PF02375.19, score=32.4]} {Human: ENSG00000066135, KDM4A, lysine demethylase 4A, [Score=371, Expect=4e-117]; ENSG00000107077, KDM4C, lysine demethylase 4C, [Score=367, Expect=1e-115]; ENSG00000127663, KDM4B, lysine demethylase 4B, [Score=353, Expect=4e-110]} {Mouse: ENSMUSG00000033326, Kdm4a, lysine (K)-specific demethylase 4A, [Score=373, Expect=3e-118]; ENSMUSG00000028397, Kdm4c, lysine (K)-specific demethylase 4C, [Score=365, Expect=2e-115]} {Dmel: FBgn0053182, Kdm4B, Lysine (K)-specific demethylase 4B, [Score=361, Expect=9e-119]} {Celegans: WBGene00012982, jmjd-2, Lysine-specific demethylase 4, [Score=309, Expect=2e-95]} {Smed: dd_Smed_v6_10489_0_2, dd_Smed_v6_10489_0_2, [Score=331, Expect=3e-109]} {RNA1509_38626} {RNA1310_14809.1} {RNA815_23117}

Mlig455_021090 {REF} {Length: 2449} {TRANSSPLICED} {Pfam: JmjC domain, hydroxylase [PF02373.24, score=142.4]; jmjN domain [PF02375.19, score=32.4]} {Human: ENSG00000066135, KDM4A, lysine demethylase 4A, [Score=369, Expect=7e-117]; ENSG00000107077, KDM4C, lysine demethylase 4C, [Score=368, Expect=3e-116]; ENSG00000127663, KDM4B, lysine demethylase 4B, [Score=354, Expect=7e-111]} {Mouse: ENSMUSG00000033326, Kdm4a, lysine (K)-specific demethylase 4A, [Score=372, Expect=4e-118]; ENSMUSG00000028397, Kdm4c, lysine (K)-specific demethylase 4C, [Score=367, Expect=5e-116]} {Dmel: FBgn0053182, Kdm4B, Lysine (K)-specific demethylase 4B, [Score=361, Expect=1e-118]} {Celegans: WBGene00012982, jmjd-2, Lysine-specific demethylase 4, [Score=308, Expect=2e-95]} {Smed: dd_Smed_v6_10489_0_2, dd_Smed_v6_10489_0_2, [Score=330, Expect=8e-109]} {RNA1509_38626} {RNA1310_14809.2, RNA1509_38626} {RNA1509_38626, RNA815_23117}
84. MligTC455_05827 107 2.23 Mlig455_026680

Neo: -

Age: Up-Down-Up

 0.984 - - 0.984 - - - Mlig455_026680 {REF} {Length: 2237} {TRANSSPLICED} {RNA1509_15690} {RNA1310_208} {RNA815_15163}
85. MligTC455_09903 33 0.68 Mlig455_051109

Neo: Irradiation

Age: Up-Down-Down

 WNT5A 0.984 - - 0.984 - - - Mlig455_051109 {REF} {Length: 3244} {Pfam: wnt family [PF00110.21, score=260.2]} {Human: ENSG00000114251, WNT5A, Wnt family member 5A, [Score=247, Expect=1e-73]; ENSG00000111186, WNT5B, Wnt family member 5B, [Score=243, Expect=3e-72]} {Mouse: ENSMUSG00000021994, Wnt5a, wingless-type MMTV integration site family, member 5A, [Score=247, Expect=8e-74]; ENSMUSG00000030170, Wnt5b, wingless-type MMTV integration site family, member 5B, [Score=245, Expect=4e-73]} {Dmel: FBgn0010194, Wnt5, Wnt oncogene analog 5, [RH, Score=160, Expect=4e-40]} {Celegans: WBGene00000858, cwn-2, [Score=221, Expect=1e-64]} {Smed: dd_Smed_v6_15469_0_1, dd_Smed_v6_15469_0_1, [Score=243, Expect=9e-73]} {RNA1509_24293} {RNA1310_13535} {RNA815_8371}
86. MligTC455_14698 87 1.81 Mlig455_016423, Mlig455_018959

Neo: -

Age: -

 0.984 - - 0.984 - - -

Mlig455_016423 {REF} {Length: 2126} {Pfam: Endonuclease-reverse transcriptase [PF14529.8, score=29.9]} {RNA1509_50390} {RNA1310_55547}

Mlig455_018959 {REF} {Length: 3176} {Pfam: Endonuclease-reverse transcriptase [PF14529.8, score=56.9]; RNase H [PF00075.26, score=47.4]; Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=23.8]; PHD-finger [PF00628.31, score=20.1]} {RNA1509_50390} {RNA1310_33666, RNA1509_50390}
87. MligTC455_15417 38 0.79 Mlig455_044351

Neo: -

Age: -

 0.984 - - 0.984 - - - Mlig455_044351 {REF} {Length: 4044} {Pfam: Peptidase family M13 [PF05649.15, score=21.3]} {RNA1310_137072}
88. MligTC455_16005 97 2.02 Mlig455_018551, Mlig455_019423, Mlig455_058389

Neo: -

Age: -

 0.984 - - 0.984 - - -

Mlig455_018551 {REF} {Length: 3430} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.1]} {RNA1509_42342} {RNA1310_4557} {RNA815_16034.1}

Mlig455_019423 {REF} {Length: 2545} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.1]} {RNA1509_42342} {RNA1310_4557} {RNA815_16034.1}

Mlig455_058389 {REF} {Length: 3494} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.1]} {RNA1509_42342} {RNA1310_4557} {RNA815_16034.1}
89. MligTC455_20050 973 20.26 Mlig455_065833

Neo: -

Age: -

Region-enriched R4: 1.188/0.00583
Region-enriched R5: 1.083/0.00271

 RMDN1 0.984 - - 0.984 - - - Mlig455_065833 {REF} {Length: 1101} {Pfam: Tetratricopeptide repeat [PF14559.8, score=26.9]; Tetratricopeptide repeat [PF13431.8, score=24.2]; Tetratricopeptide repeat [PF07719.19, score=22.1]; Tetratricopeptide repeat [PF13181.8, score=22.1]; Tetratricopeptide repeat [PF13428.8, score=21.8]; TPR repeat [PF13414.8, score=18.9]; Tetratricopeptide repeat [PF00515.30, score=18.7]} {Human: ENSG00000176623, RMDN1, regulator of microtubule dynamics 1, [RH, Score=202, Expect=2e-62]} {Mouse: ENSMUSG00000028229, Rmdn1, regulator of microtubule dynamics 1, [RH, Score=206, Expect=3e-64]} {Celegans: WBGene00009369, F33H2.6, [Score=151, Expect=1e-43]} {Smed: dd_Smed_v6_502_0_1, dd_Smed_v6_502_0_1, [Score=215, Expect=3e-69]} {RNA1509_42854} {RNA1310_19566.1} {RNA815_10877}
90. MligTC455_27032 114 2.37 Mlig455_028640

Neo: -

Age: -

 0.984 - - 0.984 - - - Mlig455_028640 {REF} {Length: 7331} {RNA1509_51520} {RNA1310_36812, RNA1509_51520} {RNA1509_51520, RNA815_27203}
91. MligTC455_36451 93 1.94 Mlig455_019217

Neo: -

Age: -

 FBXW7 0.984 - - 0.984 - - - Mlig455_019217 {REF} {Length: 2707} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=132.2]; F-box-like [PF12937.9, score=48.0]; F-box domain [PF00646.35, score=32.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=23.4]; Nucleoporin Nup120/160 [PF11715.10, score=22.5]} {Human: ENSG00000109670, FBXW7, F-box and WD repeat domain containing 7, [RH, Score=430, Expect=5e-143]} {Mouse: ENSMUSG00000028086, Fbxw7, F-box and WD-40 domain protein 7, [RH, Score=429, Expect=8e-143]} {Dmel: FBgn0041171, ago, archipelago, [RH, Score=415, Expect=2e-131]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [RH, Score=310, Expect=3e-98]} {Smed: dd_Smed_v6_8211_0_1, dd_Smed_v6_8211_0_1, [RH, Score=280, Expect=1e-88]} {RNA1509_19180, RNA1509_52969} {RNA1310_4381, RNA1509_19180, RNA1509_52969} {RNA1509_19180, RNA1509_52969, RNA815_6050}
92. MligTC455_36663 88 1.83 Mlig455_003351

Neo: -

Age: -

 0.984 - - 0.984 - - - Mlig455_003351 {REF} {Length: 2190} {TRANSSPLICED} {Pfam: F-box domain [PF00646.35, score=31.2]; F-box-like [PF12937.9, score=22.1]} {RNA1310_18711} {RNA815_25785}
93. MligTC455_39054 393 8.19 Mlig455_027098

Neo: -

Age: -

 0.984 - - 0.984 - - - Mlig455_027098 {REF} {Length: 3225} {TRANSSPLICED} {RNA1509_25890} {RNA1310_34328} {RNA815_25249}
94. MligTC455_44386 437 9.1 Mlig455_012895

Neo: -

Age: logFC(26M/2M)=-0.237

 ITK 0.984 - - 0.984 - - - Mlig455_012895 {REF} {Length: 6093} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=267.7]; Protein kinase domain [PF00069.27, score=135.1]; SH2 domain [PF00017.26, score=82.8]; PH domain [PF00169.31, score=51.1]; BTK motif [PF00779.21, score=37.2]; SH3 domain [PF00018.30, score=32.1]; Variant SH3 domain [PF14604.8, score=28.1]; Variant SH3 domain [PF07653.19, score=19.5]} {Human: ENSG00000113263, ITK, IL2 inducible T cell kinase, [RH, Score=452, Expect=6e-151]; ENSG00000010671, BTK, Bruton tyrosine kinase, [RH, Score=450, Expect=2e-149]; ENSG00000135605, TEC, tec protein tyrosine kinase, [RH, Score=439, Expect=3e-145]} {Mouse: ENSMUSG00000031264, Btk, Bruton agammaglobulinemia tyrosine kinase, [RH, Score=450, Expect=2e-149]; ENSMUSG00000029217, Tec, tec protein tyrosine kinase, [RH, Score=439, Expect=1e-145]; ENSMUSG00000020395, Itk, IL2 inducible T cell kinase, [RH, Score=439, Expect=7e-146]} {Dmel: FBgn0003502, Btk29A, Btk family kinase at 29A, [RH, Score=439, Expect=7e-144]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=314, Expect=2e-99]} {Smed: dd_Smed_v6_4818_0_1, dd_Smed_v6_4818_0_1, [RH, Score=663, Expect=0.0]} {RNA1509_14118, RNA1509_20637, RNA1509_33645, RNA1509_41278, RNA1509_43358} {RNA1310_11225, RNA1509_14118, RNA1509_20637, RNA1509_33645, RNA1509_41278, RNA1509_43358} {RNA1509_14118, RNA1509_20637, RNA1509_33645, RNA1509_41278, RNA1509_43358, RNA815_1375.1}
95. MligTC455_47813 237 4.94 Mlig455_032907

Neo: -

Age: -

 MYEF2 0.984 - - 0.984 - - - Mlig455_032907 {REF} {Length: 2139} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=138.4]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=23.8]; RNA binding motif [PF08777.13, score=20.5]; DbpA RNA binding domain [PF03880.17, score=19.0]} {Human: ENSG00000104177, MYEF2, myelin expression factor 2, [RH, Score=121, Expect=9e-30]} {Mouse: ENSMUSG00000049230, Gm9833, predicted gene 9833, [RH, Score=118, Expect=3e-29]; ENSMUSG00000027201, Myef2, myelin basic protein expression factor 2, repressor, [RH, Score=118, Expect=2e-29]; ENSMUSG00000059208, Hnrnpm, heterogeneous nuclear ribonucleoprotein M, [RH, Score=113, Expect=6e-27]} {Dmel: FBgn0267790, rump, rumpelstiltskin, [Score=112, Expect=1e-26]} {Celegans: WBGene00007706, C25A1.4, [RH, Score=107, Expect=1e-25]} {Smed: dd_Smed_v6_2707_0_1, dd_Smed_v6_2707_0_1, [RH, Score=144, Expect=2e-38]} {RNA1509_26000} {RNA1310_2998.1} {RNA815_978}
96. MligTC455_53173 127 2.65 Mlig455_019835

Neo: -

Age: Up-Down-Up

 FOXF1 0.984 - - 0.984 - - - Mlig455_019835 {REF} {Length: 2628} {Pfam: Forkhead domain [PF00250.20, score=119.5]} {Human: ENSG00000103241, FOXF1, forkhead box F1, [RH, Score=190, Expect=3e-55]} {Mouse: ENSMUSG00000042812, Foxf1, forkhead box F1, [RH, Score=187, Expect=5e-54]; ENSMUSG00000038402, Foxf2, forkhead box F2, [RH, Score=184, Expect=2e-52]} {Dmel: FBgn0045759, bin, biniou, [RH, Score=158, Expect=2e-41]} {Celegans: WBGene00002601, let-381, [Score=159, Expect=3e-44]} {Smed: dd_Smed_v6_6910_0_1, dd_Smed_v6_6910_0_1, [RH, Score=182, Expect=5e-50]} {RNA1310_14608} {RNA815_18583}
97. MligTC455_05557 49 1.02 Mlig455_054327

Neo: -

Age: -

Region-enriched R4: 4.473/0.00273

 0.983 - - 0.983 - - - Mlig455_054327 {REF} {Length: 519} {NoTransDecoderORF} {RNA1509_38197} {RNA1310_90831} {RNA815_43533}
98. MligTC455_11718 110 2.3 Mlig455_009100

Neo: -

Age: -

Region-enriched R4: 2.495/0.04544

 0.983 - - 0.983 - - - Mlig455_009100 {REF} {Length: 1916} {TRANSSPLICED} {RNA1509_23206} {RNA1310_55434} {RNA815_29179}
99. MligTC455_20934 148 3.08 Mlig455_022793

Neo: -

Age: -

 SLC35B2 0.983 - - 0.983 - - - Mlig455_022793 {REF} {Length: 2141} {TRANSSPLICED} {Pfam: UAA transporter family [PF08449.13, score=193.5]; Triose-phosphate Transporter family [PF03151.18, score=22.6]} {Human: ENSG00000157593, SLC35B2, solute carrier family 35 member B2, [Score=304, Expect=4e-99]} {Mouse: ENSMUSG00000037089, Slc35b2, solute carrier family 35, member B2, [Score=292, Expect=1e-94]} {Dmel: FBgn0038524, sll, slalom, [Score=299, Expect=3e-97]} {Celegans: WBGene00004206, pst-1, Adenosine 3'-phospho 5'-phosphosulfate transporter 1, [Score=213, Expect=2e-64]} {Smed: dd_Smed_v6_6703_0_1, dd_Smed_v6_6703_0_1, [Score=310, Expect=1e-101]} {RNA1509_31007} {RNA1310_17324, RNA1509_31007} {RNA1509_31007, RNA815_8280.1}
100. MligTC455_21584 67 1.4 Mlig455_003528, Mlig455_015537

Neo: -

Age: Down-Up-Up

 0.983 - - 0.983 - - -

Mlig455_003528 {REF} {Length: 1918} {RNA1509_49780} {RNA1310_119490} {RNA815_59473}

Mlig455_015537 {REF} {Length: 2027} {RNA1509_49780} {RNA1310_61012} {RNA815_59473}

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