Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_53045 | 1316 | 27.42 | Mlig455_026988 | Neo: - Age: Down-Down-Up Region-enriched R4: 1.692/0.00217 |
DYNLL1 | Mlig455_026988 {REF} {Length: 830} {Pfam: Dynein light chain type 1 [PF01221.20, score=67.9]; EF hand [PF00036.34, score=47.4]; EF-hand domain pair [PF13499.8, score=44.1]; EF-hand domain [PF13405.8, score=36.6]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=29.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=18.7]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=51.2, Expect=2e-08]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=49.3, Expect=1e-07]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=51.2, Expect=1e-08]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=49.3, Expect=8e-08]} {Dmel: FBgn0011760, ctp, cut up, [Score=49.7, Expect=4e-08]} {Celegans: WBGene00043067, dlc-5, Dynein Light Chain, [Score=50.1, Expect=1e-07]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=134, Expect=6e-40]} {RNA1509_3612} {RNA1310_33488} {RNA815_4208} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -2.143 | 5.033 | 0.05564 | 0.54760 | |
RegionR2 | -0.794 | 5.033 | 0.06915 | 0.31986 | |
RegionR3 | 0.055 | 5.033 | 0.87416 | 1.00000 | |
RegionR4 | 1.692 | 5.033 | 0.00014 | 0.00217 | |
RegionR5 | 0.374 | 5.033 | 0.28934 | 0.62035 | |
RegionR6 | 0.433 | 5.033 | 0.21980 | 0.79942 | |
RegionR7 | 0.231 | 5.033 | 0.57807 | 1.00000 | |
RegionR8 | 0.152 | 5.033 | 0.76411 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.26 | 5.033 | 0.89589 | 1.00000 | |
RegenerationR2 | 0.419 | 5.033 | 0.24740 | 0.69481 | |
RegenerationR3 | -0.085 | 5.033 | 0.82610 | 0.98974 | |
RegenerationR4 | -0.411 | 5.033 | 0.31939 | 0.75769 | |
RegenerationR5 | -0.252 | 5.033 | 0.51227 | 0.86512 | |
RegenerationR6 | -0.436 | 5.033 | 0.26473 | 0.61469 | |
RegenerationBL | -0.791 | 5.033 | 0.06359 | 0.29282 | |
RegenerationTP | -0.252 | 5.033 | 0.57098 | 0.94497 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_53045 | 1316 | 27.42 | Mlig455_026988 | Neo: - Age: Down-Down-Up Region-enriched R4: 1.692/0.00217 |
DYNLL1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_026988 {REF} {Length: 830} {Pfam: Dynein light chain type 1 [PF01221.20, score=67.9]; EF hand [PF00036.34, score=47.4]; EF-hand domain pair [PF13499.8, score=44.1]; EF-hand domain [PF13405.8, score=36.6]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=29.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=18.7]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=51.2, Expect=2e-08]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=49.3, Expect=1e-07]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=51.2, Expect=1e-08]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=49.3, Expect=8e-08]} {Dmel: FBgn0011760, ctp, cut up, [Score=49.7, Expect=4e-08]} {Celegans: WBGene00043067, dlc-5, Dynein Light Chain, [Score=50.1, Expect=1e-07]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=134, Expect=6e-40]} {RNA1509_3612} {RNA1310_33488} {RNA815_4208} |
2. | MligTC455_07847 | 1096 | 22.84 | Mlig455_012556, Mlig455_012557, Mlig455_012561 | Neo: - Age: Down-Up-Down |
FRK, LCK, YES1 | 1.786 | - | - | - | - | 0.953 | 0.833 | Mlig455_012556 {REF} {Length: 708} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.4]; Protein kinase domain [PF00069.27, score=135.8]; Haspin like kinase domain [PF12330.10, score=20.1]; Kinase-like [PF14531.8, score=18.9]} {Human: ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=229, Expect=3e-72]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=8e-68]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=1e-67]} {Mouse: ENSMUSG00000019779, Frk, fyn-related kinase, [Score=223, Expect=9e-70]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=2e-68]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=217, Expect=9e-68]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=216, Expect=8e-67]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=215, Expect=1e-66]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=214, Expect=1e-66]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=213, Expect=3e-66]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=238, Expect=6e-76]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=237, Expect=7e-76]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=257, Expect=9e-84]} {RNA1509_39741} {RNA1310_36414} {RNA815_3276.1} Mlig455_012557 {REF} {Length: 2434} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=283.3]; Protein kinase domain [PF00069.27, score=161.5]; SH3 domain [PF00018.30, score=49.1]; SH2 domain [PF00017.26, score=47.6]; Variant SH3 domain [PF07653.19, score=34.0]; Variant SH3 domain [PF14604.8, score=29.9]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]; Haspin like kinase domain [PF12330.10, score=19.3]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=371, Expect=1e-122]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=1e-120]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=359, Expect=9e-118]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=358, Expect=6e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=358, Expect=4e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=354, Expect=7e-116]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=374, Expect=9e-124]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=362, Expect=2e-119]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=360, Expect=5e-118]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=358, Expect=6e-118]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=3e-117]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=376, Expect=1e-124]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=374, Expect=8e-125]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=456, Expect=8e-157]} {RNA1509_27796, RNA1509_39741, RNA1509_58341} {RNA1310_9777, RNA1509_39741, RNA1509_58341} {RNA1509_39741, RNA1509_58341, RNA815_3276.1} Mlig455_012561 {REF} {Length: 2422} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.7]; Protein kinase domain [PF00069.27, score=86.2]; Haspin like kinase domain [PF12330.10, score=20.3]; Kinase-like [PF14531.8, score=19.7]} {Human: ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=137, Expect=6e-39]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=137, Expect=9e-39]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000000938, FGR, FGR proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=6e-38]} {Mouse: ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000028874, Fgr, FGR proto-oncogene, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=137, Expect=5e-39]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=136, Expect=8e-39]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=136, Expect=9e-39]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=4e-38]; ENSMUSG00000027579, Srms, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites, [Score=134, Expect=6e-38]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=140, Expect=2e-39]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=135, Expect=3e-41]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=143, Expect=1e-41]} {RNA1509_27796} {RNA1310_9777} {RNA815_3276.1} |
3. | MligTC455_42370 | 1918 | 39.97 | Mlig455_064104 | Neo: - Age: logFC(26M/2M)=-0.367 |
CAV1 | 1.757 | - | - | - | - | 0.803 | 0.954 | Mlig455_064104 {REF} {Length: 2616} {Pfam: Caveolin [PF01146.19, score=143.1]} {Human: ENSG00000105974, CAV1, caveolin 1, [RH, Score=117, Expect=4e-31]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [RH, Score=122, Expect=4e-33]} {Celegans: WBGene00000302, cav-2, Caveolin-2, [RH, Score=77.0, Expect=1e-15]} {Smed: dd_Smed_v6_6535_0_2, dd_Smed_v6_6535_0_2, [Score=91.7, Expect=2e-22]} {RNA1509_42761} {RNA1310_10782.2} {RNA815_16688.1} |
4. | MligTC455_28604 | 84 | 1.76 | Mlig455_013316 | Neo: - Age: logFC(26M/2M)=0.675 |
MYH7 | 0.963 | - | - | - | - | 0.963 | - | Mlig455_013316 {REF} {Length: 10806} {Pfam: Myosin tail [PF01576.21, score=241.4]; Intermediate filament protein [PF00038.23, score=36.6]; Crescentin protein [PF19220.2, score=32.1]; Autophagy protein 16 (ATG16) [PF08614.13, score=21.5]; bZIP transcription factor [PF00170.23, score=19.3]; Transforming acidic coiled-coil-containing protein (TACC), C-terminal [PF05010.16, score=18.8]} {Human: ENSG00000092054, MYH7, myosin heavy chain 7, [Score=378, Expect=2e-111]; ENSG00000197616, MYH6, myosin heavy chain 6, [Score=375, Expect=1e-110]; ENSG00000109061, MYH1, myosin heavy chain 1, [Score=365, Expect=4e-107]; ENSG00000125414, MYH2, myosin heavy chain 2, [Score=362, Expect=5e-106]} {Mouse: ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [Score=383, Expect=3e-113]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [Score=377, Expect=3e-111]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [Score=365, Expect=4e-107]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [Score=364, Expect=6e-107]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [Score=383, Expect=2e-113]} {Celegans: WBGene00006754, unc-15, Paramyosin, [Score=328, Expect=7e-99]} {Smed: dd_Smed_v6_711_0_1, dd_Smed_v6_711_0_1, [RH, Score=842, Expect=0.0]} {RNA1509_2272} {RNA1310_1994.1, RNA1509_2272} {RNA1509_2272, RNA815_1258} |
5. | MligTC455_39270 | 44 | 0.92 | Mlig455_031895 | Neo: - Age: - |
0.96 | - | - | - | - | 0.960 | - | Mlig455_031895 {REF} {Length: 1332} {Pfam: Adenovirus endoprotease [PF00770.20, score=20.9]} {RNA1509_37388} {RNA1310_436.1} {RNA815_24633} | |
6. | MligTC455_26263 | 70 | 1.45 | Mlig455_040654 | Neo: - Age: Up-Down-Down |
NR1I3 | 0.959 | - | - | - | - | 0.959 | - | Mlig455_040654 {REF} {Length: 4785} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.2]} {Human: ENSG00000143257, NR1I3, nuclear receptor subfamily 1 group I member 3, [Score=103, Expect=1e-23]} {Mouse: ENSMUSG00000005677, Nr1i3, nuclear receptor subfamily 1, group I, member 3, [Score=99.8, Expect=3e-22]; ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=99.4, Expect=1e-21]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=95.5, Expect=2e-20]} {Dmel: FBgn0015240, Hr96, Hormone receptor-like in 96, [Score=98.2, Expect=7e-21]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=112, Expect=2e-25]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=183, Expect=2e-50]} {RNA1509_15212} {RNA1310_18440} {RNA815_11206} |
7. | MligTC455_08444 | 39 | 0.81 | Mlig455_067929 | Neo: - Age: - |
0.957 | - | - | - | - | 0.957 | - | Mlig455_067929 {REF} {Length: 1240} {Pfam: Adenovirus endoprotease [PF00770.20, score=20.6]} {RNA1509_37388} {RNA1310_15837} {RNA815_24633} | |
8. | MligTC455_16691 | 57 | 1.18 | Mlig455_018665 | Neo: - Age: - Region-enriched R8: 7.774/0.00104 |
0.956 | - | - | - | - | 0.956 | - | Mlig455_018665 {REF} {Length: 709} {NoTransDecoderORF} {RNA1509_25022} {RNA1310_77757} {RNA815_23623} | |
9. | MligTC455_29580 | 523 | 10.89 | Mlig455_004620, Mlig455_004629, Mlig455_004656 | Neo: - Age: - Region-enriched R8: 2.467/0.03081 |
AP1S2 | 0.956 | - | - | - | - | 0.956 | - | Mlig455_004620 {REF} {Length: 2855} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.9]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=261, Expect=2e-90]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=252, Expect=5e-87]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=261, Expect=1e-90]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=252, Expect=3e-87]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=282, Expect=3e-99]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=278, Expect=9e-98]} {Smed: dd_Smed_v6_2365_0_1, dd_Smed_v6_2365_0_1, [RH, Score=274, Expect=5e-96]} {RNA1509_14918} {RNA1310_4459.1} {RNA815_4627} Mlig455_004629 {REF} {Length: 2802} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.6]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=269, Expect=2e-93]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=263, Expect=3e-91]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=269, Expect=1e-93]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=263, Expect=2e-91]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=262, Expect=4e-91]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [Score=256, Expect=1e-88]} {Smed: dd_Smed_v6_9393_0_2, dd_Smed_v6_9393_0_2, [RH, Score=262, Expect=3e-91]} {RNA1509_14918} {RNA1310_4459.1} {RNA815_3355.1} Mlig455_004656 {REF} {Length: 1887} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.6]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=270, Expect=7e-94]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=263, Expect=6e-91]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=270, Expect=5e-94]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=263, Expect=4e-91]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=262, Expect=3e-91]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [Score=256, Expect=8e-89]} {Smed: dd_Smed_v6_9393_0_2, dd_Smed_v6_9393_0_2, [RH, Score=263, Expect=1e-91]} {RNA1509_14918} {RNA1310_7376.1} {RNA815_4627} |
10. | MligTC455_39586 | 18 | 0.38 | Mlig455_048851 | Neo: - Age: - |
0.955 | - | - | - | - | 0.955 | - | Mlig455_048851 {REF} {Length: 1847} {NoTransDecoderORF} {RNA1509_25886} {RNA1310_11504.1} {RNA815_17069.1} | |
11. | MligTC455_28686 | 23 | 0.47 | Mlig455_011407 | Neo: - Age: - |
0.951 | - | - | - | - | 0.951 | - | Mlig455_011407 {REF} {Length: 383} {TRANSSPLICED} {RNA1509_35740} {RNA1310_43519} {RNA815_21134} | |
12. | MligTC455_51935 | 200 | 4.16 | Mlig455_036791 | Neo: - Age: - |
CMPK1 | 0.951 | - | - | - | - | 0.951 | - | Mlig455_036791 {REF} {Length: 1554} {Pfam: Adenylate kinase [PF00406.24, score=105.0]; AAA domain [PF13207.8, score=67.2]; AAA domain [PF13238.8, score=20.3]} {Human: ENSG00000162368, CMPK1, cytidine/uridine monophosphate kinase 1, [Score=149, Expect=8e-44]} {Mouse: ENSMUSG00000028719, Cmpk1, cytidine monophosphate (UMP-CMP) kinase 1, [Score=150, Expect=3e-44]} {Dmel: FBgn0028833, Dak1, [Score=143, Expect=3e-41]} {Celegans: WBGene00007812, C29F7.3, UMP-CMP kinase 1, [Score=137, Expect=4e-40]} {Smed: dd_Smed_v6_3353_0_1, dd_Smed_v6_3353_0_1, [Score=132, Expect=9e-38]} {RNA1509_39811} {RNA1310_32882, RNA1509_39811} {RNA1509_39811, RNA815_17820.1} |