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Results for MligTC455_53045

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53045 1316 27.42 Mlig455_026988

Neo: -

Age: Down-Down-Up

Region-enriched R4: 1.692/0.00217

DYNLL1 Mlig455_026988 {REF} {Length: 830} {Pfam: Dynein light chain type 1 [PF01221.20, score=67.9]; EF hand [PF00036.34, score=47.4]; EF-hand domain pair [PF13499.8, score=44.1]; EF-hand domain [PF13405.8, score=36.6]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=29.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=18.7]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=51.2, Expect=2e-08]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=49.3, Expect=1e-07]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=51.2, Expect=1e-08]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=49.3, Expect=8e-08]} {Dmel: FBgn0011760, ctp, cut up, [Score=49.7, Expect=4e-08]} {Celegans: WBGene00043067, dlc-5, Dynein Light Chain, [Score=50.1, Expect=1e-07]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=134, Expect=6e-40]} {RNA1509_3612} {RNA1310_33488} {RNA815_4208}

Cumulative graph for MligTC455_53045

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.143 5.033 0.05564 0.54760
RegionR2 -0.794 5.033 0.06915 0.31986
RegionR3 0.055 5.033 0.87416 1.00000
RegionR4 1.692 5.033 0.00014 0.00217
RegionR5 0.374 5.033 0.28934 0.62035
RegionR6 0.433 5.033 0.21980 0.79942
RegionR7 0.231 5.033 0.57807 1.00000
RegionR8 0.152 5.033 0.76411 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.26 5.033 0.89589 1.00000
RegenerationR2 0.419 5.033 0.24740 0.69481
RegenerationR3 -0.085 5.033 0.82610 0.98974
RegenerationR4 -0.411 5.033 0.31939 0.75769
RegenerationR5 -0.252 5.033 0.51227 0.86512
RegenerationR6 -0.436 5.033 0.26473 0.61469
RegenerationBL -0.791 5.033 0.06359 0.29282
RegenerationTP -0.252 5.033 0.57098 0.94497


Genes with expression patterns similar to MligTC455_53045

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53045 1316 27.42 Mlig455_026988

Neo: -

Age: Down-Down-Up

Region-enriched R4: 1.692/0.00217

DYNLL1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_026988 {REF} {Length: 830} {Pfam: Dynein light chain type 1 [PF01221.20, score=67.9]; EF hand [PF00036.34, score=47.4]; EF-hand domain pair [PF13499.8, score=44.1]; EF-hand domain [PF13405.8, score=36.6]; EF hand [PF13202.8, score=35.1]; EF-hand domain pair [PF13833.8, score=29.2]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=18.7]} {Human: ENSG00000088986, DYNLL1, dynein light chain LC8-type 1, [Score=51.2, Expect=2e-08]; ENSG00000264364, DYNLL2, dynein light chain LC8-type 2, [Score=49.3, Expect=1e-07]} {Mouse: ENSMUSG00000009013, Dynll1, dynein light chain LC8-type 1, [Score=51.2, Expect=1e-08]; ENSMUSG00000020483, Dynll2, dynein light chain LC8-type 2, [Score=49.3, Expect=8e-08]} {Dmel: FBgn0011760, ctp, cut up, [Score=49.7, Expect=4e-08]} {Celegans: WBGene00043067, dlc-5, Dynein Light Chain, [Score=50.1, Expect=1e-07]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=134, Expect=6e-40]} {RNA1509_3612} {RNA1310_33488} {RNA815_4208}
2. MligTC455_07847 1096 22.84 Mlig455_012556, Mlig455_012557, Mlig455_012561

Neo: -

Age: Down-Up-Down

FRK, LCK, YES1 1.786 - - - - 0.953 0.833

Mlig455_012556 {REF} {Length: 708} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.4]; Protein kinase domain [PF00069.27, score=135.8]; Haspin like kinase domain [PF12330.10, score=20.1]; Kinase-like [PF14531.8, score=18.9]} {Human: ENSG00000111816, FRK, fyn related Src family tyrosine kinase, [Score=229, Expect=3e-72]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=8e-68]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=1e-67]} {Mouse: ENSMUSG00000019779, Frk, fyn-related kinase, [Score=223, Expect=9e-70]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=218, Expect=2e-68]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=217, Expect=9e-68]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=216, Expect=8e-67]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=215, Expect=1e-66]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=214, Expect=1e-66]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=213, Expect=3e-66]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=238, Expect=6e-76]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=237, Expect=7e-76]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=257, Expect=9e-84]} {RNA1509_39741} {RNA1310_36414} {RNA815_3276.1}

Mlig455_012557 {REF} {Length: 2434} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=283.3]; Protein kinase domain [PF00069.27, score=161.5]; SH3 domain [PF00018.30, score=49.1]; SH2 domain [PF00017.26, score=47.6]; Variant SH3 domain [PF07653.19, score=34.0]; Variant SH3 domain [PF14604.8, score=29.9]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]; Haspin like kinase domain [PF12330.10, score=19.3]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=371, Expect=1e-122]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=366, Expect=1e-120]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=359, Expect=9e-118]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=358, Expect=6e-118]; ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=358, Expect=4e-117]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=354, Expect=7e-116]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=374, Expect=9e-124]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=362, Expect=2e-119]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=360, Expect=5e-118]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=358, Expect=6e-118]; ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=357, Expect=3e-117]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=376, Expect=1e-124]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=374, Expect=8e-125]} {Smed: dd_Smed_v6_3363_0_1, dd_Smed_v6_3363_0_1, [Score=456, Expect=8e-157]} {RNA1509_27796, RNA1509_39741, RNA1509_58341} {RNA1310_9777, RNA1509_39741, RNA1509_58341} {RNA1509_39741, RNA1509_58341, RNA815_3276.1}

Mlig455_012561 {REF} {Length: 2422} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=153.7]; Protein kinase domain [PF00069.27, score=86.2]; Haspin like kinase domain [PF12330.10, score=20.3]; Kinase-like [PF14531.8, score=19.7]} {Human: ENSG00000176105, YES1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSG00000197122, SRC, SRC proto-oncogene, non-receptor tyrosine kinase, [Score=137, Expect=6e-39]; ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=137, Expect=9e-39]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000000938, FGR, FGR proto-oncogene, Src family tyrosine kinase, [Score=136, Expect=1e-38]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=6e-38]} {Mouse: ENSMUSG00000014932, Yes1, YES proto-oncogene 1, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000028874, Fgr, FGR proto-oncogene, Src family tyrosine kinase, [Score=139, Expect=1e-39]; ENSMUSG00000027646, Src, Rous sarcoma oncogene, [Score=137, Expect=5e-39]; ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=136, Expect=8e-39]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=136, Expect=9e-39]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=134, Expect=4e-38]; ENSMUSG00000027579, Srms, src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites, [Score=134, Expect=6e-38]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=140, Expect=2e-39]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=135, Expect=3e-41]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=143, Expect=1e-41]} {RNA1509_27796} {RNA1310_9777} {RNA815_3276.1}
3. MligTC455_42370 1918 39.97 Mlig455_064104

Neo: -

Age: logFC(26M/2M)=-0.367

CAV1 1.757 - - - - 0.803 0.954 Mlig455_064104 {REF} {Length: 2616} {Pfam: Caveolin [PF01146.19, score=143.1]} {Human: ENSG00000105974, CAV1, caveolin 1, [RH, Score=117, Expect=4e-31]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [RH, Score=122, Expect=4e-33]} {Celegans: WBGene00000302, cav-2, Caveolin-2, [RH, Score=77.0, Expect=1e-15]} {Smed: dd_Smed_v6_6535_0_2, dd_Smed_v6_6535_0_2, [Score=91.7, Expect=2e-22]} {RNA1509_42761} {RNA1310_10782.2} {RNA815_16688.1}
4. MligTC455_28604 84 1.76 Mlig455_013316

Neo: -

Age: logFC(26M/2M)=0.675

MYH7 0.963 - - - - 0.963 - Mlig455_013316 {REF} {Length: 10806} {Pfam: Myosin tail [PF01576.21, score=241.4]; Intermediate filament protein [PF00038.23, score=36.6]; Crescentin protein [PF19220.2, score=32.1]; Autophagy protein 16 (ATG16) [PF08614.13, score=21.5]; bZIP transcription factor [PF00170.23, score=19.3]; Transforming acidic coiled-coil-containing protein (TACC), C-terminal [PF05010.16, score=18.8]} {Human: ENSG00000092054, MYH7, myosin heavy chain 7, [Score=378, Expect=2e-111]; ENSG00000197616, MYH6, myosin heavy chain 6, [Score=375, Expect=1e-110]; ENSG00000109061, MYH1, myosin heavy chain 1, [Score=365, Expect=4e-107]; ENSG00000125414, MYH2, myosin heavy chain 2, [Score=362, Expect=5e-106]} {Mouse: ENSMUSG00000060180, Myh13, myosin, heavy polypeptide 13, skeletal muscle, [Score=383, Expect=3e-113]; ENSMUSG00000053093, Myh7, myosin, heavy polypeptide 7, cardiac muscle, beta, [Score=377, Expect=3e-111]; ENSMUSG00000033196, Myh2, myosin, heavy polypeptide 2, skeletal muscle, adult, [Score=365, Expect=4e-107]; ENSMUSG00000056328, Myh1, myosin, heavy polypeptide 1, skeletal muscle, adult, [Score=364, Expect=6e-107]} {Dmel: FBgn0264695, Mhc, Myosin heavy chain, [Score=383, Expect=2e-113]} {Celegans: WBGene00006754, unc-15, Paramyosin, [Score=328, Expect=7e-99]} {Smed: dd_Smed_v6_711_0_1, dd_Smed_v6_711_0_1, [RH, Score=842, Expect=0.0]} {RNA1509_2272} {RNA1310_1994.1, RNA1509_2272} {RNA1509_2272, RNA815_1258}
5. MligTC455_39270 44 0.92 Mlig455_031895

Neo: -

Age: -

0.96 - - - - 0.960 - Mlig455_031895 {REF} {Length: 1332} {Pfam: Adenovirus endoprotease [PF00770.20, score=20.9]} {RNA1509_37388} {RNA1310_436.1} {RNA815_24633}
6. MligTC455_26263 70 1.45 Mlig455_040654

Neo: -

Age: Up-Down-Down

NR1I3 0.959 - - - - 0.959 - Mlig455_040654 {REF} {Length: 4785} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=73.2]} {Human: ENSG00000143257, NR1I3, nuclear receptor subfamily 1 group I member 3, [Score=103, Expect=1e-23]} {Mouse: ENSMUSG00000005677, Nr1i3, nuclear receptor subfamily 1, group I, member 3, [Score=99.8, Expect=3e-22]; ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=99.4, Expect=1e-21]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=95.5, Expect=2e-20]} {Dmel: FBgn0015240, Hr96, Hormone receptor-like in 96, [Score=98.2, Expect=7e-21]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=112, Expect=2e-25]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=183, Expect=2e-50]} {RNA1509_15212} {RNA1310_18440} {RNA815_11206}
7. MligTC455_08444 39 0.81 Mlig455_067929

Neo: -

Age: -

0.957 - - - - 0.957 - Mlig455_067929 {REF} {Length: 1240} {Pfam: Adenovirus endoprotease [PF00770.20, score=20.6]} {RNA1509_37388} {RNA1310_15837} {RNA815_24633}
8. MligTC455_16691 57 1.18 Mlig455_018665

Neo: -

Age: -

Region-enriched R8: 7.774/0.00104
Region-enriched R7: 6.459/0.00277

0.956 - - - - 0.956 - Mlig455_018665 {REF} {Length: 709} {NoTransDecoderORF} {RNA1509_25022} {RNA1310_77757} {RNA815_23623}
9. MligTC455_29580 523 10.89 Mlig455_004620, Mlig455_004629, Mlig455_004656

Neo: -

Age: -

Region-enriched R8: 2.467/0.03081
Region-enriched R7: 2.313/0.00806

AP1S2 0.956 - - - - 0.956 -

Mlig455_004620 {REF} {Length: 2855} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.9]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=261, Expect=2e-90]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=252, Expect=5e-87]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=261, Expect=1e-90]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=252, Expect=3e-87]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=282, Expect=3e-99]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [RH, Score=278, Expect=9e-98]} {Smed: dd_Smed_v6_2365_0_1, dd_Smed_v6_2365_0_1, [RH, Score=274, Expect=5e-96]} {RNA1509_14918} {RNA1310_4459.1} {RNA815_4627}

Mlig455_004629 {REF} {Length: 2802} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.6]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=269, Expect=2e-93]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=263, Expect=3e-91]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=269, Expect=1e-93]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=263, Expect=2e-91]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=262, Expect=4e-91]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [Score=256, Expect=1e-88]} {Smed: dd_Smed_v6_9393_0_2, dd_Smed_v6_9393_0_2, [RH, Score=262, Expect=3e-91]} {RNA1509_14918} {RNA1310_4459.1} {RNA815_3355.1}

Mlig455_004656 {REF} {Length: 1887} {TRANSSPLICED} {Pfam: Clathrin adaptor complex small chain [PF01217.22, score=193.6]} {Human: ENSG00000182287, AP1S2, adaptor related protein complex 1 subunit sigma 2, [RH, Score=270, Expect=7e-94]; ENSG00000106367, AP1S1, adaptor related protein complex 1 subunit sigma 1, [RH, Score=263, Expect=6e-91]} {Mouse: ENSMUSG00000031367, Ap1s2, adaptor-related protein complex 1, sigma 2 subunit, [RH, Score=270, Expect=5e-94]; ENSMUSG00000004849, Ap1s1, adaptor protein complex AP-1, sigma 1, [RH, Score=263, Expect=4e-91]} {Dmel: FBgn0039132, AP-1sigma, Adaptor Protein complex 1, sigma subunit, [RH, Score=262, Expect=3e-91]} {Celegans: WBGene00000159, aps-1, AdaPtin, Small chain (Clathrin associated complex), [Score=256, Expect=8e-89]} {Smed: dd_Smed_v6_9393_0_2, dd_Smed_v6_9393_0_2, [RH, Score=263, Expect=1e-91]} {RNA1509_14918} {RNA1310_7376.1} {RNA815_4627}
10. MligTC455_39586 18 0.38 Mlig455_048851

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_048851 {REF} {Length: 1847} {NoTransDecoderORF} {RNA1509_25886} {RNA1310_11504.1} {RNA815_17069.1}
11. MligTC455_28686 23 0.47 Mlig455_011407

Neo: -

Age: -

0.951 - - - - 0.951 - Mlig455_011407 {REF} {Length: 383} {TRANSSPLICED} {RNA1509_35740} {RNA1310_43519} {RNA815_21134}
12. MligTC455_51935 200 4.16 Mlig455_036791

Neo: -

Age: -

CMPK1 0.951 - - - - 0.951 - Mlig455_036791 {REF} {Length: 1554} {Pfam: Adenylate kinase [PF00406.24, score=105.0]; AAA domain [PF13207.8, score=67.2]; AAA domain [PF13238.8, score=20.3]} {Human: ENSG00000162368, CMPK1, cytidine/uridine monophosphate kinase 1, [Score=149, Expect=8e-44]} {Mouse: ENSMUSG00000028719, Cmpk1, cytidine monophosphate (UMP-CMP) kinase 1, [Score=150, Expect=3e-44]} {Dmel: FBgn0028833, Dak1, [Score=143, Expect=3e-41]} {Celegans: WBGene00007812, C29F7.3, UMP-CMP kinase 1, [Score=137, Expect=4e-40]} {Smed: dd_Smed_v6_3353_0_1, dd_Smed_v6_3353_0_1, [Score=132, Expect=9e-38]} {RNA1509_39811} {RNA1310_32882, RNA1509_39811} {RNA1509_39811, RNA815_17820.1}

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