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Results for MligTC455_43667

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_43667 251 5.24 Mlig455_070631

Neo: -

Age: Down-Down-Up

KY Mlig455_070631 {REF} {Length: 5010} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=151, Expect=4e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=2e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=136, Expect=4e-32]} {RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1310_2203, RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1509_26818, RNA1509_52206, RNA1509_7582, RNA815_6135}

Cumulative graph for MligTC455_43667

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.555 2.898 0.22054 0.86378
RegionR2 1.839 2.898 0.07433 0.33309
RegionR3 1.617 2.898 0.05326 0.40504
RegionR4 1.343 2.898 0.20241 0.48292
RegionR5 0.56 2.898 0.56037 0.92007
RegionR6 1.08 2.898 0.26030 0.84800
RegionR7 -2.059 2.898 0.99918 1.00000
RegionR8 1.176 2.898 0.31327 0.94547

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.285 2.898 0.99991 1.00000
RegenerationR2 0.447 2.898 0.47158 0.85832
RegenerationR3 -0.366 2.898 0.61356 0.91426
RegenerationR4 -0.579 2.898 0.46455 0.84997
RegenerationR5 -0.792 2.898 0.29470 0.72231
RegenerationR6 -0.494 2.898 0.53481 0.83004
RegenerationBL 1.146 2.898 0.21062 0.55401
RegenerationTP 0.685 2.898 0.53218 0.92212


Genes with expression patterns similar to MligTC455_43667

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_43667 251 5.24 Mlig455_070631

Neo: -

Age: Down-Down-Up

KY 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_070631 {REF} {Length: 5010} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=114, Expect=3e-25]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=151, Expect=4e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=2e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=136, Expect=4e-32]} {RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1310_2203, RNA1509_26818, RNA1509_52206, RNA1509_7582} {RNA1509_26818, RNA1509_52206, RNA1509_7582, RNA815_6135}
2. MligTC455_27904 110 2.29 Mlig455_028965

Neo: -

Age: -

3.443 - - 0.955 0.721 0.959 0.808 Mlig455_028965 {REF} {Length: 8009} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=50.4, Expect=7e-06]} {RNA1509_4697} {RNA1310_228} {RNA815_3412.1}
3. MligTC455_43666 172 3.59 Mlig455_051408

Neo: -

Age: logFC(26M/2M)=-0.352

KY 3.387 - 0.954 0.798 0.724 0.911 - Mlig455_051408 {REF} {Length: 5047} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=111, Expect=2e-24]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=111, Expect=1e-24]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=150, Expect=7e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=1e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=137, Expect=1e-32]} {RNA1509_7582} {RNA1310_2203} {RNA815_6135}
4. MligTC455_24074 1066 22.21 Mlig455_048222

Neo: -

Age: -

Region-enriched R2: 1.734/0.02628

3.367 - 0.965 - 0.764 0.837 0.801 Mlig455_048222 {REF} {Length: 2364} {Smed: dd_Smed_v6_8763_0_1, dd_Smed_v6_8763_0_1, [RH, Score=101, Expect=1e-23]} {RNA1509_5814} {RNA1310_13945, RNA1509_5814} {RNA1509_5814, RNA815_5072}
5. MligTC455_38084 643 13.39 Mlig455_044428, Mlig455_044462

Neo: -

Age: -

ZNF347, ZNF850 3.288 - - 0.964 0.810 0.786 0.728

Mlig455_044428 {REF} {Length: 5133} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=53.4]; C2H2-type zinc finger [PF13894.8, score=28.2]; Zinc-finger of C2H2 type [PF12874.9, score=19.4]} {Human: ENSG00000267041, ZNF850, zinc finger protein 850, [Score=54.7, Expect=6e-07]} {RNA1509_7797} {RNA1310_1145} {RNA815_319.1}

Mlig455_044462 {REF} {Length: 6499} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=88.8]; C2H2-type zinc finger [PF13894.8, score=73.9]; C2H2-type zinc finger [PF13912.8, score=39.0]; C2HE / C2H2 / C2HC zinc-binding finger [PF16278.7, score=19.0]} {Human: ENSG00000197937, ZNF347, zinc finger protein 347, [Score=80.5, Expect=1e-14]; ENSG00000281709, ZNF197, zinc finger protein 197, [Score=78.2, Expect=9e-14]; ENSG00000186448, ZNF197, zinc finger protein 197, [Score=78.2, Expect=9e-14]} {Mouse: ENSMUSG00000034538, Zfp418, zinc finger protein 418, [Score=72.8, Expect=2e-12]; ENSMUSG00000058883, Zfp708, zinc finger protein 708, [Score=72.0, Expect=3e-12]; ENSMUSG00000037640, Zfp60, zinc finger protein 60, [Score=70.9, Expect=9e-12]} {Dmel: FBgn0261679, CG42726, [Score=57.0, Expect=7e-08]} {Celegans: WBGene00003847, blmp-1, B lymphocyte-induced maturation protein 1 homolog, [Score=52.0, Expect=3e-06]} {RNA1509_47351} {RNA1310_1145} {RNA815_319.1}
6. MligTC455_51933 583 12.15 Mlig455_024511

Neo: -

Age: logFC(26M/2M)=-0.429

Region-enriched R2: 2.089/0.00081

CBSL 2.702 - 0.952 - 0.823 0.927 - Mlig455_024511 {REF} {Length: 1959} {Pfam: Pyridoxal-phosphate dependent enzyme [PF00291.27, score=138.0]; CBS domain [PF00571.30, score=48.9]} {Human: ENSG00000274276, CBSL, cystathionine-beta-synthase like, [Score=463, Expect=3e-160]; ENSG00000160200, CBS, cystathionine-beta-synthase, [Score=463, Expect=3e-160]} {Mouse: ENSMUSG00000024039, Cbs, cystathionine beta-synthase, [Score=467, Expect=6e-162]} {Dmel: FBgn0031148, Cbs, centrosomin's beautiful sister, [Score=327, Expect=2e-107]} {Celegans: WBGene00013866, cbs-1, Cystathionine Beta-Synthase, [Score=264, Expect=2e-81]} {Smed: dd_Smed_v6_1585_0_1, dd_Smed_v6_1585_0_1, [Score=511, Expect=6e-180]} {RNA1509_36721} {RNA1310_10809} {RNA815_3797.1}
7. MligTC455_17371 402 8.37 Mlig455_057595

Neo: -

Age: Up-Down-Up

FRMPD2 2.689 - 0.957 - - 0.911 0.821 Mlig455_057595 {REF} {Length: 6274} {Pfam: PDZ domain [PF00595.26, score=116.9]; PDZ domain [PF17820.3, score=53.9]; FERM central domain [PF00373.20, score=34.0]; PDZ domain [PF13180.8, score=29.8]; FERM C-terminal PH-like domain [PF09380.12, score=20.6]} {Human: ENSG00000170324, FRMPD2, FERM and PDZ domain containing 2, [Score=94.0, Expect=2e-18]; ENSG00000163629, PTPN13, protein tyrosine phosphatase, non-receptor type 13, [Score=93.6, Expect=4e-18]} {Mouse: ENSMUSG00000034573, Ptpn13, protein tyrosine phosphatase, non-receptor type 13, [Score=94.4, Expect=1e-18]} {Dmel: FBgn0004583, ex, expanded, [Score=65.9, Expect=4e-10]} {Celegans: WBGene00001492, frm-5.1, FERM domain (Protein4.1-ezrin-radixin-moesin) family, [Score=77.4, Expect=1e-13]} {Smed: dd_Smed_v6_3493_1_1, dd_Smed_v6_3493_1_1, [Score=75.9, Expect=7e-14]} {RNA1509_18922, RNA1509_42494} {RNA1310_439, RNA1509_42494} {RNA1509_42494, RNA815_23639}
8. MligTC455_33343 459 9.56 Mlig455_063303

Neo: -

Age: -

Region-enriched R2: 1.600/0.01675

ITPR1 2.682 - - - 0.816 0.955 0.911 Mlig455_063303 {REF} {Length: 3962} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=68.3]; Ion transport protein [PF00520.33, score=28.7]} {Human: ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=166, Expect=6e-41]} {Mouse: ENSMUSG00000030102, Itpr1, inositol 1,4,5-trisphosphate receptor 1, [Score=182, Expect=7e-46]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=179, Expect=4e-45]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=155, Expect=5e-38]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1044, Expect=0.0]} {RNA1509_30811} {RNA1310_939} {RNA815_220}
9. MligTC455_40201 607 12.65 Mlig455_052028

Neo: -

Age: logFC(26M/2M)=-0.526

DCLK3 2.644 0.863 0.966 - - 0.815 - Mlig455_052028 {REF} {Length: 3990} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.8]; Fungal protein kinase [PF17667.3, score=26.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.0]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=370, Expect=2e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=8e-110]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=369, Expect=3e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=295, Expect=7e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=351, Expect=2e-105]} {RNA1509_13597} {RNA1310_2158.1} {RNA815_2598}
10. MligTC455_16801 252 5.24 Mlig455_001186

Neo: Irradiation

Age: -

ERBB3 2.634 - 0.954 - - 0.784 0.896 Mlig455_001186 {REF} {Length: 5931} {Human: ENSG00000065361, ERBB3, erb-b2 receptor tyrosine kinase 3, [Score=61.6, Expect=5e-10]; ENSG00000178568, ERBB4, erb-b2 receptor tyrosine kinase 4, [Score=58.9, Expect=5e-09]} {Mouse: ENSMUSG00000018166, Erbb3, erb-b2 receptor tyrosine kinase 3, [Score=60.1, Expect=2e-09]; ENSMUSG00000062209, Erbb4, erb-b2 receptor tyrosine kinase 4, [Score=58.9, Expect=4e-09]; ENSMUSG00000020122, Egfr, epidermal growth factor receptor, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_10624_0_1, dd_Smed_v6_10624_0_1, [Score=51.6, Expect=4e-07]} {RNA1509_7929} {RNA1310_1321, RNA1509_7929} {RNA1509_7929, RNA815_2089}
11. MligTC455_40202 595 12.39 Mlig455_057253

Neo: -

Age: logFC(26M/2M)=-0.440

DCLK3 2.62 0.828 0.968 - - 0.824 - Mlig455_057253 {REF} {Length: 4012} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.9]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=371, Expect=1e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=2e-113]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=370, Expect=1e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=296, Expect=6e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=352, Expect=1e-105]} {RNA1509_13597, RNA1509_49808} {RNA1310_2158.1, RNA1509_13597, RNA1509_49808} {RNA1509_13597, RNA1509_49808, RNA815_2598}
12. MligTC455_46197 1085 22.61 Mlig455_032287, Mlig455_047132, Mlig455_047137, Mlig455_068482

Neo: -

Age: -

KREMEN2 2.617 - - - 0.872 0.951 0.794

Mlig455_032287 {REF} {Length: 948} {Pfam: WSC domain [PF01822.21, score=59.5]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=56.6, Expect=5e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=68.2, Expect=5e-13]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=57.0, Expect=3e-09]} {RNA1509_59284} {RNA1310_43884} {RNA815_21749.2}

Mlig455_047132 {REF} {Length: 1046} {Pfam: WSC domain [PF01822.21, score=60.6]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=48.9, Expect=2e-06]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=48.9, Expect=1e-06]; ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=47.4, Expect=5e-06]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=51.6, Expect=2e-07]} {RNA1509_59284} {RNA1310_43884} {RNA815_21749.2}

Mlig455_047137 {REF} {Length: 1045} {Pfam: WSC domain [PF01822.21, score=51.2]} {RNA1509_59284} {RNA1310_43884} {RNA815_21749.2}

Mlig455_068482 {REF} {Length: 965} {Pfam: WSC domain [PF01822.21, score=57.6]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.4, Expect=1e-07]; ENSG00000179314, WSCD1, WSC domain containing 1, [Score=52.4, Expect=2e-07]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=53.5, Expect=4e-08]; ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=52.4, Expect=1e-07]; ENSMUSG00000020811, Wscd1, WSC domain containing 1, [Score=51.2, Expect=2e-07]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=45.8, Expect=9e-06]} {RNA1509_59284} {RNA1310_52794.1} {RNA815_21749.1}
13. MligTC455_41828 699 14.57 Mlig455_055575

Neo: -

Age: -

2.585 - - - 0.893 0.985 0.707 Mlig455_055575 {REF} {Length: 3023} {Dmel: FBgn0264693, ens, ensconsin, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_5361_0_1, dd_Smed_v6_5361_0_1, [RH, Score=65.1, Expect=1e-10]} {RNA1509_19058, RNA1509_59334} {RNA1310_6742.2, RNA1509_59334} {RNA1509_59334, RNA815_12863}
14. MligTC455_53167 621 12.93 Mlig455_035205, Mlig455_035254

Neo: -

Age: -

TEP1 2.57 - - 0.786 0.818 - 0.966

Mlig455_035205 {REF} {Length: 3182} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=143, Expect=4e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=121, Expect=2e-27]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=335, Expect=8e-102]} {RNA1509_45368, RNA1509_7043} {RNA1310_6418, RNA1509_45368} {RNA1509_45368, RNA815_7934}

Mlig455_035254 {REF} {Length: 3176} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=42.8]; NACHT domain [PF05729.14, score=19.7]; AAA ATPase domain [PF13191.8, score=19.7]} {Human: ENSG00000129566, TEP1, telomerase associated protein 1, [Score=142, Expect=6e-34]} {Mouse: ENSMUSG00000006281, Tep1, telomerase associated protein 1, [Score=119, Expect=1e-26]} {Smed: dd_Smed_v6_9074_0_1, dd_Smed_v6_9074_0_1, [RH, Score=329, Expect=2e-99]} {RNA1509_7043} {RNA1310_6418, RNA1509_7043} {RNA1509_7043, RNA815_7934}
15. MligTC455_43741 196 4.08 Mlig455_018088

Neo: -

Age: Down-Up-Down

PTBP1 2.562 - - 0.742 0.850 0.970 - Mlig455_018088 {REF} {Length: 2775} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=116.9]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=52.7]; Occluded RNA-recognition motif [PF16842.7, score=26.8]} {Human: ENSG00000011304, PTBP1, polypyrimidine tract binding protein 1, [Score=258, Expect=8e-80]; ENSG00000117569, PTBP2, polypyrimidine tract binding protein 2, [Score=258, Expect=1e-80]; ENSG00000119314, PTBP3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-76]} {Mouse: ENSMUSG00000028134, Ptbp2, polypyrimidine tract binding protein 2, [Score=258, Expect=7e-81]; ENSMUSG00000006498, Ptbp1, polypyrimidine tract binding protein 1, [Score=251, Expect=1e-78]; ENSMUSG00000028382, Ptbp3, polypyrimidine tract binding protein 3, [Score=248, Expect=1e-77]} {Dmel: FBgn0011224, heph, hephaestus, [Score=249, Expect=7e-78]} {Celegans: WBGene00004207, ptb-1, PTB (HnRNP) homolog; Putative RNA-binding protein PTB-1b, [Score=234, Expect=1e-72]} {Smed: dd_Smed_v6_1868_0_1, dd_Smed_v6_1868_0_1, [Score=214, Expect=4e-64]} {RNA1509_36451} {RNA1310_3345} {RNA815_23519}
16. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

TTC16 2.537 - 0.957 - - 0.859 0.721 Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
17. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 2.535 - - 0.725 0.847 0.963 -

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
18. MligTC455_24058 874 18.21 Mlig455_049588

Neo: -

Age: logFC(26M/2M)=0.283

SYTL4 2.534 - - - 0.776 0.961 0.797 Mlig455_049588 {REF} {Length: 12642} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=68.1]; FYVE-type zinc finger [PF02318.18, score=53.4]; Protein of unknown function (DUF3139) [PF11337.10, score=20.6]} {Human: ENSG00000102362, SYTL4, synaptotagmin like 4, [Score=100, Expect=3e-20]; ENSG00000147041, SYTL5, synaptotagmin like 5, [Score=99.0, Expect=1e-19]} {Mouse: ENSMUSG00000031255, Sytl4, synaptotagmin-like 4, [Score=100, Expect=3e-20]} {Dmel: FBgn0266756, btsz, bitesize, [Score=117, Expect=2e-25]} {Celegans: WBGene00004923, snt-3, SyNapTotagmin, [Score=57.8, Expect=5e-08]} {Smed: dd_Smed_v6_4335_0_1, dd_Smed_v6_4335_0_1, [Score=84.7, Expect=5e-16]} {RNA1509_12528, RNA1509_2527} {RNA1310_245.3, RNA1509_12528} {RNA1509_12528, RNA815_559.1}
19. MligTC455_27638 969 20.19 Mlig455_022789

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.917

CLUAP1 2.52 - 0.956 - 0.740 0.824 - Mlig455_022789 {REF} {Length: 2458} {Pfam: Clusterin-associated protein-1 [PF10234.11, score=358.0]} {Human: ENSG00000103351, CLUAP1, clusterin associated protein 1, [RH, Score=332, Expect=1e-110]} {Mouse: ENSMUSG00000014232, Cluap1, clusterin associated protein 1, [RH, Score=330, Expect=8e-110]} {Dmel: FBgn0031196, CG17599, [RH, Score=135, Expect=1e-34]} {Celegans: WBGene00001119, dyf-3, Clusterin-associated protein 1 homolog, [RH, Score=215, Expect=1e-65]} {Smed: dd_Smed_v6_8287_0_1, dd_Smed_v6_8287_0_1, [RH, Score=333, Expect=2e-110]} {RNA1509_14292, RNA1509_25335} {RNA1310_15979, RNA1509_14292, RNA1509_25335} {RNA1509_14292, RNA1509_25335, RNA815_6417.1}
20. MligTC455_38148 787 16.4 Mlig455_067155

Neo: -

Age: -

FAT1 2.501 - - - 0.816 0.969 0.716 Mlig455_067155 {REF} {Length: 4823} {Pfam: Cadherin domain [PF00028.19, score=183.7]; EGF-like domain [PF00008.29, score=55.8]; Calcium-binding EGF domain [PF07645.17, score=31.4]; Laminin G domain [PF02210.26, score=24.7]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=292, Expect=3e-79]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=299, Expect=2e-81]} {Dmel: FBgn0261574, kug, kugelei, [Score=213, Expect=3e-55]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=189, Expect=9e-48]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=218, Expect=1e-56]} {RNA1509_13557} {RNA1310_1912.1} {RNA815_14235}
21. MligTC455_15598 45 0.94 Mlig455_021461

Neo: -

Age: Down-Up-Up

2.5 - - - 0.731 0.966 0.803 Mlig455_021461 {REF} {Length: 2020} {RNA1310_35982.1} {RNA815_27626}
22. MligTC455_53960 381 7.93 Mlig455_039523

Neo: -

Age: logFC(26M/2M)=-0.527

Region-enriched R2: 1.863/0.02753

TTLL7 2.491 - - 0.765 0.742 0.984 - Mlig455_039523 {REF} {Length: 2811} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=44.5]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=146, Expect=5e-37]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=261, Expect=2e-76]} {Dmel: FBgn0039501, CG5987, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=118, Expect=1e-27]} {RNA1509_8901} {RNA1310_4651} {RNA815_1757}
23. MligTC455_18787 963 20.06 Mlig455_014022

Neo: -

Age: -

Region-enriched R2: 1.334/0.03482

STRC 2.49 - 0.743 - - 0.958 0.789 Mlig455_014022 {REF} {Length: 5754} {Human: ENSG00000242866, STRC, stereocilin, [RH, Score=76.3, Expect=4e-13]} {Mouse: ENSMUSG00000033498, Strc, stereocilin, [RH, Score=80.9, Expect=1e-14]} {RNA1509_4378} {RNA1310_1493.1, RNA1509_4378} {RNA1509_4378, RNA815_804}
24. MligTC455_52238 282 5.87 Mlig455_029211

Neo: -

Age: logFC(26M/2M)=-0.312

ABCG2 2.485 - 0.955 - - 0.801 0.729 Mlig455_029211 {REF} {Length: 3240} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=80.5, Expect=3e-15]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=79.0, Expect=7e-15]} {Smed: dd_Smed_v6_4225_0_1, dd_Smed_v6_4225_0_1, [Score=108, Expect=2e-24]} {RNA1509_38878} {RNA1310_949.2} {RNA815_1895}
25. MligTC455_23587 421 8.78 Mlig455_007553

Neo: -

Age: Down-Up-Down

CNBD1 2.467 0.721 0.950 - - 0.796 - Mlig455_007553 {REF} {Length: 1538} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=32.7]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=6e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=216, Expect=2e-64]} {RNA1509_35878} {RNA1310_17903} {RNA815_7217}
26. MligTC455_44176 89 1.85 Mlig455_022911

Neo: -

Age: -

TNKS 2.464 - - - 0.794 0.963 0.707 Mlig455_022911 {REF} {Length: 1883} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=67.0]; Ankyrin repeats (3 copies) [PF12796.9, score=64.6]; Ankyrin repeats (many copies) [PF13857.8, score=59.2]; Ankyrin repeat [PF13606.8, score=50.9]; Ankyrin repeat [PF00023.32, score=50.1]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=57.8, Expect=3e-08]; ENSG00000285372, AC270292.3, tankyrase, [Score=56.6, Expect=7e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=57.8, Expect=1e-08]; ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=57.8, Expect=1e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=57.8, Expect=2e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=57.4, Expect=1e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.8, Expect=9e-08]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=55.5, Expect=8e-08]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.5, Expect=1e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=55.5, Expect=4e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=55.1, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=55.1, Expect=8e-08]} {Dmel: FBgn0040752, Prosap, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=62.0, Expect=4e-10]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
27. MligTC455_53961 290 6.04 Mlig455_051313

Neo: -

Age: logFC(26M/2M)=-0.591

Region-enriched R2: 2.488/0.02898

TTLL7 2.457 - - 0.709 0.775 0.973 - Mlig455_051313 {REF} {Length: 3404} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=247.2]; Sugar-transfer associated ATP-grasp [PF14397.8, score=21.8]; YheC/D like ATP-grasp [PF14398.8, score=18.8]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [RH, Score=478, Expect=1e-157]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [RH, Score=474, Expect=2e-153]} {Dmel: FBgn0039501, CG5987, [Score=289, Expect=2e-85]} {Celegans: WBGene00019230, ttll-11, Tubulin Tyrosine Ligase Like, [Score=184, Expect=5e-49]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [RH, Score=408, Expect=4e-128]} {RNA1509_8901} {RNA1310_4651, RNA1509_8901} {RNA1509_8901, RNA815_1757}
28. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

POU4F3 2.454 - - - 0.744 0.971 0.739

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
29. MligTC455_25030 401 8.35 Mlig455_014751

Neo: -

Age: Down-Up-Down

2.439 - - 0.777 - 0.704 0.958 Mlig455_014751 {REF} {Length: 2349} {RNA1509_19923} {RNA1310_20222} {RNA815_2554}
30. MligTC455_36295 1177 24.51 Mlig455_024718

Neo: Int S/G2/M

Age: Up-Down-Down, logFC(26M/2M)=-0.419

2.437 - 0.955 - 0.759 0.723 - Mlig455_024718 {REF} {Length: 8865} {Pfam: RyR and IP3R Homology associated [PF08454.13, score=53.1]; RIH domain [PF01365.23, score=49.3]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=48.2]; MIR domain [PF02815.21, score=43.5]; Ion transport protein [PF00520.33, score=21.8]} {Smed: dd_Smed_v6_13538_0_1, dd_Smed_v6_13538_0_1, [Score=879, Expect=0.0]} {RNA1509_1471, RNA1509_34147} {RNA1310_176.1, RNA1509_34147} {RNA1509_34147, RNA815_70}
31. MligTC455_38828 995 20.73 Mlig455_009774, Mlig455_054924

Neo: -

Age: Down-Up-Down

Region-enriched R8: 1.773/0.01787
Region-enriched R7: 1.452/0.03515

CELSR2 2.426 - - 0.749 0.713 0.964 -

Mlig455_009774 {REF} {Length: 2779} {Pfam: Cadherin domain [PF00028.19, score=114.6]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=110, Expect=3e-24]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=107, Expect=3e-23]} {Dmel: FBgn0039294, Cad96Cb, Cadherin 96Cb, [RH, Score=133, Expect=7e-32]} {Celegans: WBGene00000401, cdh-9, CaDHerin family, [RH, Score=79.7, Expect=3e-15]} {Smed: dd_Smed_v6_14410_0_1, dd_Smed_v6_14410_0_1, [Score=77.0, Expect=2e-14]} {RNA1509_6574} {RNA1310_7530, RNA1509_6574} {RNA1509_6574, RNA815_2409}

Mlig455_054924 {REF} {Length: 2736} {Pfam: Cadherin domain [PF00028.19, score=113.4]} {Human: ENSG00000143126, CELSR2, cadherin EGF LAG seven-pass G-type receptor 2, [Score=108, Expect=1e-23]} {Mouse: ENSMUSG00000068740, Celsr2, cadherin, EGF LAG seven-pass G-type receptor 2, [Score=104, Expect=2e-22]} {Dmel: FBgn0039294, Cad96Cb, Cadherin 96Cb, [RH, Score=130, Expect=5e-31]} {Celegans: WBGene00000401, cdh-9, CaDHerin family, [RH, Score=82.8, Expect=3e-16]} {Smed: dd_Smed_v6_14410_0_1, dd_Smed_v6_14410_0_1, [Score=78.2, Expect=9e-15]} {RNA1509_57757, RNA1509_6574} {RNA1310_7530, RNA1509_57757} {RNA1509_57757, RNA815_2409}
32. MligTC455_31872 115 2.4 Mlig455_031280

Neo: -

Age: -

2.411 - - - 0.707 0.972 0.732 Mlig455_031280 {REF} {Length: 4437} {RNA1509_44223} {RNA1310_53789} {RNA815_61017}
33. MligTC455_43683 520 10.83 Mlig455_029440

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.407

2.407 - - 0.737 0.701 0.969 - Mlig455_029440 {REF} {Length: 1842} {RNA1509_21217} {RNA1310_16933.1, RNA1509_21217} {RNA1509_21217, RNA815_7959}
34. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 2.376 - - - 0.709 0.966 0.701

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
35. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

ABCG2 1.936 - 0.971 - - 0.965 - Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
36. MligTC455_15330 373 7.77 Mlig455_020220

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.289

1.884 - - - 0.932 0.952 - Mlig455_020220 {REF} {Length: 2115} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=41.4]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=82.0, Expect=3e-20]} {RNA1509_28885, RNA1509_54654} {RNA1310_42962.2, RNA1509_28885, RNA1509_54654} {RNA1509_28885, RNA1509_54654, RNA815_23071}
37. MligTC455_27649 366 7.62 Mlig455_017718, Mlig455_057045

Neo: -

Age: logFC(26M/2M)=0.439

ADAM9 1.828 - - - 0.872 0.956 -

Mlig455_017718 {REF} {Length: 3325} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=133.0]; Disintegrin [PF00200.25, score=68.9]; Metallo-peptidase family M12 [PF13688.8, score=68.7]; ADAM cysteine-rich [PF08516.14, score=58.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=52.3]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=44.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=32.0]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=272, Expect=2e-78]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=268, Expect=1e-76]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [RH, Score=276, Expect=2e-79]} {Dmel: FBgn0265140, Meltrin, [Score=262, Expect=7e-73]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=263, Expect=9e-75]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=247, Expect=2e-68]} {RNA1509_19133, RNA1509_24635, RNA1509_4260, RNA1509_50111} {RNA1310_4299.1, RNA1509_19133, RNA1509_24635, RNA1509_50111} {RNA1509_19133, RNA1509_24635, RNA1509_50111, RNA815_11215.1}

Mlig455_057045 {REF} {Length: 3286} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=133.0]; Disintegrin [PF00200.25, score=69.2]; Metallo-peptidase family M12 [PF13688.8, score=68.8]; ADAM cysteine-rich [PF08516.14, score=58.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=52.3]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=44.6]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=32.0]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [RH, Score=273, Expect=2e-78]; ENSG00000151651, ADAM8, ADAM metallopeptidase domain 8, [RH, Score=268, Expect=7e-77]} {Mouse: ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [RH, Score=280, Expect=5e-81]} {Dmel: FBgn0265140, Meltrin, [Score=259, Expect=5e-73]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=263, Expect=8e-75]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=247, Expect=2e-68]} {RNA1509_22944, RNA1509_4260} {RNA1310_4299.1, RNA1509_22944, RNA1509_4260} {RNA1509_22944, RNA1509_4260, RNA815_11215.1}
38. MligTC455_34723 441 9.2 Mlig455_051959

Neo: -

Age: Up-Down-Down

NIM1K 1.823 - 0.974 - - - 0.849 Mlig455_051959 {REF} {Length: 3455} {Pfam: Protein kinase domain [PF00069.27, score=116.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=56.1]; Kinase-like [PF14531.8, score=18.5]} {Human: ENSG00000177453, NIM1K, NIM1 serine/threonine protein kinase, [Score=240, Expect=1e-76]} {Mouse: ENSMUSG00000095930, Nim1k, NIM1 serine/threonine protein kinase, [Score=241, Expect=4e-77]} {Dmel: FBgn0031299, CG4629, [Score=152, Expect=3e-42]} {Celegans: WBGene00009867, F49C5.4, [Score=182, Expect=8e-54]} {Smed: dd_Smed_v6_15794_0_1, dd_Smed_v6_15794_0_1, [Score=214, Expect=1e-66]} {RNA1509_24864, RNA1509_26319} {RNA1310_21151.1, RNA1509_24864} {RNA1509_24864, RNA815_8109.1}
39. MligTC455_49663 245 5.1 Mlig455_013565

Neo: -

Age: -

CDH23 1.822 - - - - 0.969 0.853 Mlig455_013565 {REF} {Length: 7289} {Pfam: Cadherin domain [PF00028.19, score=361.2]; Cadherin-like [PF08266.14, score=38.9]} {Human: ENSG00000107736, CDH23, cadherin related 23, [Score=372, Expect=1e-103]} {Mouse: ENSMUSG00000012819, Cdh23, cadherin 23 (otocadherin), [Score=375, Expect=6e-105]} {Dmel: FBgn0038247, Cad88C, Cadherin 88C, [Score=362, Expect=2e-101]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=224, Expect=2e-58]} {Smed: dd_Smed_v6_15356_0_1, dd_Smed_v6_15356_0_1, [Score=414, Expect=3e-118]} {RNA1509_16482} {RNA1310_682} {RNA815_249}
40. MligTC455_51710 3251 67.72 Mlig455_024427

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.451

Region-enriched R8: 1.126/0.01211

1.819 - - - 0.844 0.975 - Mlig455_024427 {REF} {Length: 2323} {RNA1509_28514} {RNA1310_24129} {RNA815_10418.2}
41. MligTC455_50750 137 2.86 Mlig455_004587

Neo: -

Age: -

GNB5 1.793 - - - - 0.969 0.824 Mlig455_004587 {REF} {Length: 6245} {Pfam: WD domain, G-beta repeat [PF00400.34, score=96.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=48.4]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=26.3]; WD40-like domain [PF17005.7, score=24.1]} {Human: ENSG00000069966, GNB5, G protein subunit beta 5, [Score=411, Expect=2e-144]} {Mouse: ENSMUSG00000032192, Gnb5, guanine nucleotide binding protein (G protein), beta 5, [Score=412, Expect=9e-145]} {Dmel: FBgn0030011, Gbeta5, [Score=430, Expect=4e-152]} {Celegans: WBGene00001680, gpb-2, Guanine nucleotide-binding protein subunit beta-2, [Score=402, Expect=6e-141]} {Smed: dd_Smed_v6_10481_0_1, dd_Smed_v6_10481_0_1, [Score=476, Expect=9e-171]} {RNA1509_51468} {RNA1310_13844.1} {RNA815_14582}
42. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 1.791 - - - 0.822 0.969 -

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
43. MligTC455_15671 88 1.84 Mlig455_059458

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.370

Region-enriched R4: 4.705/0.00509

KIAA0895L 1.778 - - 0.800 - - 0.978 Mlig455_059458 {REF} {Length: 3483} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF1704) [PF08014.13, score=37.3]} {Human: ENSG00000196123, KIAA0895L, KIAA0895 like, [RH, Score=151, Expect=4e-40]; ENSG00000164542, KIAA0895, KIAA0895, [RH, Score=150, Expect=1e-39]} {Mouse: ENSMUSG00000014837, 4931428F04Rik, RIKEN cDNA 4931428F04 gene, [RH, Score=156, Expect=4e-42]} {Smed: dd_Smed_v6_103892_0_1, dd_Smed_v6_103892_0_1, [RH, Score=98.6, Expect=3e-25]} {RNA1509_47713, RNA1509_49841} {RNA1310_17536.1, RNA1509_47713, RNA1509_49841} {RNA1509_47713, RNA1509_49841, RNA815_7463.1}
44. MligTC455_13039 18 0.38 Mlig455_012224, Mlig455_069088

Neo: -

Age: -

1.77 - - - 0.811 0.959 -

Mlig455_012224 {REF} {Length: 1882} {Smed: dd_Smed_v6_9937_0_1, dd_Smed_v6_9937_0_1, [Score=177, Expect=1e-50]} {RNA1310_109660}

Mlig455_069088 {REF} {Length: 2016} {Smed: dd_Smed_v6_9937_0_1, dd_Smed_v6_9937_0_1, [Score=190, Expect=2e-55]} {RNA1310_109660}
45. MligTC455_16233 307 6.4 Mlig455_011368

Neo: -

Age: logFC(26M/2M)=-1.958

1.767 0.782 - - - 0.985 - Mlig455_011368 {REF} {Length: 1236} {RNA1509_44264} {RNA1310_62516} {RNA815_23574}
46. MligTC455_18347 118 2.46 Mlig455_000821

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.590

KCNA1 1.767 - - - 0.817 0.950 - Mlig455_000821 {REF} {Length: 3163} {Pfam: Ion transport protein [PF00520.33, score=166.1]; BTB/POZ domain [PF02214.24, score=97.8]; Ion channel [PF07885.18, score=48.4]} {Human: ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=611, Expect=0.0]; ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=611, Expect=0.0]; ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=610, Expect=0.0]; ENSG00000182255, KCNA4, potassium voltage-gated channel subfamily A member 4, [RH, Score=585, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=611, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=610, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=607, Expect=0.0]; ENSMUSG00000042604, Kcna4, potassium voltage-gated channel, shaker-related subfamily, member 4, [RH, Score=587, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=629, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=377, Expect=2e-124]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=707, Expect=0.0]} {RNA1509_47579} {RNA1310_8777} {RNA815_4701}
47. MligTC455_48103 628 13.08 Mlig455_057218

Neo: -

Age: Up-Up-Down

RGS22 1.763 - - - 0.955 0.808 - Mlig455_057218 {REF} {Length: 3461} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=26.0]} {Human: ENSG00000132554, RGS22, regulator of G protein signaling 22, [RH, Score=72.4, Expect=3e-12]} {Mouse: ENSMUSG00000037627, Rgs22, regulator of G-protein signalling 22, [RH, Score=56.6, Expect=1e-07]} {Smed: dd_Smed_v6_11778_0_1, dd_Smed_v6_11778_0_1, [Score=246, Expect=4e-68]} {RNA1509_2536} {RNA1310_3477} {RNA815_616.1}
48. MligTC455_51821 207 4.32 Mlig455_034943

Neo: -

Age: -

ZDHHC17 1.757 - - - 0.954 - 0.803 Mlig455_034943 {REF} {Length: 2788} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=95.6]; DHHC palmitoyltransferase [PF01529.22, score=88.3]; Ankyrin repeats (many copies) [PF13857.8, score=73.4]; Ankyrin repeats (many copies) [PF13637.8, score=73.3]; Ankyrin repeat [PF13606.8, score=71.9]; Ankyrin repeat [PF00023.32, score=60.9]} {Human: ENSG00000186908, ZDHHC17, zinc finger DHHC-type containing 17, [Score=171, Expect=1e-45]} {Mouse: ENSMUSG00000035798, Zdhhc17, zinc finger, DHHC domain containing 17, [Score=167, Expect=2e-44]} {Dmel: FBgn0029137, Patsas, [Score=347, Expect=1e-112]} {Celegans: WBGene00044071, dhhc-14, Palmitoyltransferase, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_16314_0_1, dd_Smed_v6_16314_0_1, [RH, Score=257, Expect=3e-79]} {RNA1509_23644, RNA1509_58425} {RNA1310_10451.2, RNA1509_23644, RNA1509_58425} {RNA1509_23644, RNA1509_58425, RNA815_5451}
49. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 1.752 - - - 0.797 0.955 - Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
50. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 1.751 - - - 0.787 0.964 - Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
51. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

1.741 0.791 - - - 0.950 - Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
52. MligTC455_37751 204 4.25 Mlig455_014157

Neo: -

Age: Up-Down-Down

Region-enriched R2: 2.173/0.03490

NWD2 1.735 - 0.961 0.774 - - - Mlig455_014157 {REF} {Length: 7240} {TRANSSPLICED} {Pfam: AAA ATPase domain [PF13191.8, score=40.0]; NACHT domain [PF05729.14, score=36.6]; Dpy-30 motif [PF05186.15, score=33.2]; AAA domain [PF13401.8, score=32.6]; Domain of unknown function (DUF4062) [PF13271.8, score=22.0]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=402, Expect=6e-114]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=395, Expect=8e-112]} {Dmel: FBgn0038397, CG10185, [Score=526, Expect=2e-156]} {Celegans: WBGene00020254, T05C3.2, [Score=521, Expect=2e-154]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=292, Expect=2e-79]} {RNA1509_7024} {RNA1310_383.1, RNA1509_7024} {RNA1509_7024, RNA815_188}
53. MligTC455_45820 864 18 Mlig455_029390

Neo: -

Age: logFC(26M/2M)=0.420

Region-enriched R2: 2.360/0.02053

TYW5 1.734 - 0.950 - - - 0.784 Mlig455_029390 {REF} {Length: 1885} {Pfam: Cupin-like domain [PF13621.8, score=119.9]; EF hand [PF13202.8, score=23.2]} {Human: ENSG00000162971, TYW5, tRNA-yW synthesizing protein 5, [Score=64.3, Expect=9e-11]} {Mouse: ENSMUSG00000030752, Kdm8, lysine (K)-specific demethylase 8, [Score=70.9, Expect=9e-13]} {Dmel: FBgn0035166, CG13902, [Score=64.3, Expect=6e-11]} {Celegans: WBGene00007387, jmjd-5, JuMonJi (Transcription factor) Domain protein, [Score=53.1, Expect=3e-07]} {Smed: dd_Smed_v6_11273_0_1, dd_Smed_v6_11273_0_1, [Score=224, Expect=1e-68]} {RNA1509_1841, RNA1509_6132} {RNA1310_16511, RNA1509_6132} {RNA1509_6132, RNA815_6144}
54. MligTC455_41324 401 8.35 Mlig455_024997

Neo: -

Age: Up-Down-Down

CCDC151 1.729 - - - - 0.955 0.774 Mlig455_024997 {REF} {Length: 2376} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1, RNA1509_18758} {RNA1509_18758, RNA815_13766}
55. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

1.729 - - - 0.767 0.962 - Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
56. MligTC455_14716 29 0.61 Mlig455_043633

Neo: -

Age: -

ANGPTL2 1.728 - - - 0.770 0.958 - Mlig455_043633 {REF} {Length: 1106} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=157.6]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=134, Expect=2e-35]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=133, Expect=4e-35]; ENSG00000085265, FCN1, ficolin 1, [Score=132, Expect=8e-36]; ENSG00000160339, FCN2, ficolin 2, [Score=128, Expect=4e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=119, Expect=6e-32]} {Celegans: WBGene00017013, ensh-1, [Score=57.8, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=114, Expect=1e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
57. MligTC455_44971 99 2.07 Mlig455_055696

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.674

Region-enriched R4: 4.753/0.00442

ATP1B1 1.726 - - - 0.773 0.953 - Mlig455_055696 {REF} {Length: 2498} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.1]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=125, Expect=7e-33]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=127, Expect=8e-34]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=164, Expect=8e-48]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=4e-43]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [RH, Score=244, Expect=2e-79]} {RNA1509_10526} {RNA1310_27937} {RNA815_16874}
58. MligTC455_40325 103 2.15 Mlig455_013035

Neo: -

Age: -

1.723 - - - 0.749 0.974 - Mlig455_013035 {REF} {Length: 653} {RNA1509_20946} {RNA1310_44606} {RNA815_35640}
59. MligTC455_04626 114 2.37 Mlig455_056977

Neo: -

Age: logFC(26M/2M)=-0.594

FHAD1 1.722 - 0.953 - - - 0.769 Mlig455_056977 {REF} {Length: 5197} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=36.8]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.1]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=130, Expect=1e-29]} {Mouse: ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=127, Expect=3e-29]; ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=127, Expect=3e-29]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=252, Expect=2e-68]} {RNA1509_11172} {RNA1310_2117.1, RNA1509_11172} {RNA1509_11172, RNA815_6949}
60. MligTC455_38593 2042 42.54 Mlig455_010843

Neo: -

Age: -

1.719 - - - - 0.955 0.764 Mlig455_010843 {REF} {Length: 1508} {Pfam: Wnt and FGF inhibitory regulator [PF13908.8, score=19.2]} {RNA1509_23850, RNA1509_53025, RNA1509_55041, RNA1509_9732} {RNA1310_24247.1, RNA1509_23850, RNA1509_53025, RNA1509_55041, RNA1509_9732} {RNA1509_23850, RNA1509_53025, RNA1509_55041, RNA1509_9732, RNA815_10484}
61. MligTC455_51072 1435 29.89 Mlig455_026765, Mlig455_051781

Neo: -

Age: logFC(26M/2M)=-0.451

1.718 - - - - 0.766 0.952

Mlig455_026765 {REF} {Length: 1860} {Pfam: Cytochrome b-c1 complex subunit 8 [PF10890.10, score=22.8]} {RNA1509_46733} {RNA1310_23599.1} {RNA815_9299.1}

Mlig455_051781 {REF} {Length: 1509} {RNA1509_22054, RNA1509_46733, RNA1509_53980} {RNA1310_23599.1, RNA1509_22054, RNA1509_46733, RNA1509_53980} {RNA1509_22054, RNA1509_46733, RNA1509_53980, RNA815_9299.1}
62. MligTC455_14130 101 2.11 Mlig455_028802

Neo: -

Age: -

Region-enriched R7: 4.171/0.00325

1.717 - - - 0.741 0.976 - Mlig455_028802 {REF} {Length: 1282} {Pfam: Lectin C-type domain [PF00059.23, score=21.4]} {RNA1509_20946} {RNA1310_33562} {RNA815_30982}
63. MligTC455_26611 643 13.39 Mlig455_024673

Neo: -

Age: Up-Down-Up

Region-enriched R4: 1.538/0.03428

RAB39B 1.716 - 0.963 - - 0.753 - Mlig455_024673 {REF} {Length: 2857} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=159.5]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=92.8]; ADP-ribosylation factor family [PF00025.23, score=40.5]; 50S ribosome-binding GTPase [PF01926.25, score=28.9]} {Human: ENSG00000155961, RAB39B, RAB39B, member RAS oncogene family, [RH, Score=189, Expect=4e-60]; ENSG00000179331, RAB39A, RAB39A, member RAS oncogene family, [RH, Score=187, Expect=2e-59]} {Mouse: ENSMUSG00000055069, Rab39, RAB39, member RAS oncogene family, [RH, Score=190, Expect=8e-61]; ENSMUSG00000031202, Rab39b, RAB39B, member RAS oncogene family, [RH, Score=189, Expect=3e-60]} {Dmel: FBgn0029959, Rab39, [RH, Score=201, Expect=3e-65]} {Celegans: WBGene00004286, rab-39, RAB family, [RH, Score=197, Expect=2e-63]} {Smed: dd_Smed_v6_3651_0_1, dd_Smed_v6_3651_0_1, [RH, Score=216, Expect=4e-71]} {RNA1509_26640, RNA1509_58665} {RNA1310_33935, RNA1509_26640, RNA1509_58665} {RNA1509_26640, RNA1509_58665, RNA815_16719}
64. MligTC455_42625 514 10.71 Mlig455_030550

Neo: -

Age: logFC(26M/2M)=-0.257

FHAD1 1.715 - - - - 0.958 0.757 Mlig455_030550 {REF} {Length: 4380} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=46.8]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=28.5]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=94.0, Expect=1e-18]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=89.4, Expect=2e-17]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=89.4, Expect=2e-17]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=122, Expect=1e-27]} {RNA1509_16296, RNA1509_55326} {RNA1310_9155.1, RNA1509_16296, RNA1509_55326} {RNA1509_16296, RNA1509_55326, RNA815_22370}
65. MligTC455_16533 307 6.41 Mlig455_001056

Neo: -

Age: -

MAP3K12 1.711 0.756 - - - 0.955 - Mlig455_001056 {REF} {Length: 5078} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=186.2]; Protein kinase domain [PF00069.27, score=149.7]} {Human: ENSG00000139625, MAP3K12, mitogen-activated protein kinase kinase kinase 12, [RH, Score=298, Expect=4e-88]; ENSG00000073803, MAP3K13, mitogen-activated protein kinase kinase kinase 13, [RH, Score=284, Expect=3e-82]} {Mouse: ENSMUSG00000023050, Map3k12, mitogen-activated protein kinase kinase kinase 12, [RH, Score=297, Expect=8e-88]; ENSMUSG00000033618, Map3k13, mitogen-activated protein kinase kinase kinase 13, [RH, Score=285, Expect=8e-83]} {Dmel: FBgn0036896, wnd, wallenda, [RH, Score=278, Expect=2e-80]} {Celegans: WBGene00001008, dlk-1, Mitogen-activated protein kinase kinase kinase dlk-1, [RH, Score=252, Expect=2e-71]} {Smed: dd_Smed_v6_8838_0_1, dd_Smed_v6_8838_0_1, [RH, Score=247, Expect=2e-69]} {RNA1509_23640, RNA1509_33629} {RNA1310_3590, RNA1509_23640, RNA1509_33629} {RNA1509_23640, RNA1509_33629, RNA815_3292}
66. MligTC455_42513 70 1.45 Mlig455_023063, Mlig455_023065

Neo: -

Age: -

KCNC2 1.711 0.748 - - - 0.963 -

Mlig455_023063 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}

Mlig455_023065 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}
67. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

CEP164 1.708 - - 0.754 - 0.954 -

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}
68. MligTC455_17309 119 2.48 Mlig455_045358

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.461

1.705 - - 0.740 - 0.965 - Mlig455_045358 {REF} {Length: 2422} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [Score=62.8, Expect=3e-12]} {RNA1310_22111} {RNA815_10307}
69. MligTC455_24536 120 2.5 Mlig455_028895

Neo: -

Age: Up-Down-Down

TRPA1 1.702 - - - - 0.978 0.724 Mlig455_028895 {REF} {Length: 4399} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.9]; Ankyrin repeats (many copies) [PF13637.8, score=235.5]; Ankyrin repeats (many copies) [PF13857.8, score=187.3]; Ankyrin repeat [PF00023.32, score=185.3]; Ankyrin repeat [PF13606.8, score=184.2]; Ion transport protein [PF00520.33, score=31.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=295, Expect=6e-83]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=277, Expect=4e-77]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=305, Expect=2e-86]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=276, Expect=1e-76]} {Smed: dd_Smed_v6_20683_0_1, dd_Smed_v6_20683_0_1, [RH, Score=551, Expect=2e-178]} {RNA1509_56559} {RNA1310_3837.1} {RNA815_4441}
70. MligTC455_25395 2547 53.06 Mlig455_012103, Mlig455_029022

Neo: -

Age: -

SLC46A3 1.702 0.737 - - - 0.965 -

Mlig455_012103 {REF} {Length: 2488} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.5]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=139, Expect=2e-35]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=5e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=2e-50]} {RNA1509_18925, RNA1509_45956} {RNA1310_14130.1, RNA1509_18925, RNA1509_45956} {RNA1509_18925, RNA1509_45956, RNA815_4522}

Mlig455_029022 {REF} {Length: 2776} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.1]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=142, Expect=2e-36]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=4e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=3e-50]} {RNA1509_18925} {RNA1310_14130.2} {RNA815_4522}
71. MligTC455_33293 190 3.95 Mlig455_039617, Mlig455_051433

Neo: -

Age: logFC(26M/2M)=-0.344

CERKL 1.698 - - - 0.734 0.964 -

Mlig455_039617 {REF} {Length: 1308} {RNA1509_27178} {RNA1310_5866.1} {RNA815_1765}

Mlig455_051433 {REF} {Length: 4899} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=53.4]; Ceramide kinase C-terminal domain [PF19280.1, score=36.3]} {Human: ENSG00000188452, CERKL, ceramide kinase like, [Score=109, Expect=3e-24]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=96.7, Expect=2e-20]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=97.4, Expect=2e-20]} {Smed: dd_Smed_v6_9323_0_1, dd_Smed_v6_9323_0_1, [Score=120, Expect=2e-28]} {RNA1509_12345, RNA1509_27178} {RNA1310_5866.1, RNA1509_12345, RNA1509_27178} {RNA1509_12345, RNA1509_27178, RNA815_1765}
72. MligTC455_44023 2719 56.64 Mlig455_004982, Mlig455_005292

Neo: -

Age: -

Region-enriched R2: 1.232/0.02120

CFAP206 1.698 - 0.958 - - 0.740 -

Mlig455_004982 {REF} {Length: 2163} {TRANSSPLICED} {Pfam: Domain of unknown function [PF12018.10, score=313.9]} {Human: ENSG00000272514, CFAP206, cilia and flagella associated protein 206, [RH, Score=600, Expect=0.0]; ENSG00000213204, AL049697.1, novel transcript, C6orf165-SLC35A1 readthrough, [RH, Score=600, Expect=0.0]} {Mouse: ENSMUSG00000028294, Cfap206, cilia and flagella associated protein 206, [RH, Score=618, Expect=0.0]} {Dmel: FBgn0034532, CG13436, [RH, Score=85.9, Expect=2e-17]} {Smed: dd_Smed_v6_11199_0_1, dd_Smed_v6_11199_0_1, [RH, Score=683, Expect=0.0]} {RNA1509_3595} {RNA1310_11402, RNA1509_3595} {RNA1509_3595, RNA815_4138}

Mlig455_005292 {REF} {Length: 2167} {TRANSSPLICED} {Pfam: Domain of unknown function [PF12018.10, score=312.8]} {Human: ENSG00000272514, CFAP206, cilia and flagella associated protein 206, [RH, Score=599, Expect=0.0]; ENSG00000213204, AL049697.1, novel transcript, C6orf165-SLC35A1 readthrough, [RH, Score=599, Expect=0.0]} {Mouse: ENSMUSG00000028294, Cfap206, cilia and flagella associated protein 206, [RH, Score=617, Expect=0.0]} {Dmel: FBgn0034532, CG13436, [RH, Score=85.1, Expect=4e-17]} {Smed: dd_Smed_v6_11199_0_1, dd_Smed_v6_11199_0_1, [RH, Score=683, Expect=0.0]} {RNA1509_3595} {RNA1310_11402} {RNA815_4138}
73. MligTC455_19266 1038 21.61 Mlig455_004528, Mlig455_028530

Neo: -

Age: -

Region-specific R2: 2.706

Region-enriched R2: 1.766/0.00005

NCALD 1.687 - - - - 0.950 0.737

Mlig455_004528 {REF} {Length: 3958} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_14564} {RNA1310_18405, RNA1509_14564} {RNA1509_14564, RNA815_10180.1}

Mlig455_028530 {REF} {Length: 3453} {tRNA: Val(CAC),pseudo, score=38.6} {Pfam: EF-hand domain pair [PF13499.8, score=74.4]; EF hand [PF00036.34, score=71.3]; EF-hand domain [PF13405.8, score=66.3]; EF hand [PF13202.8, score=62.7]; EF-hand domain pair [PF13833.8, score=50.8]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=22.1]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=19.3]} {Human: ENSG00000104490, NCALD, neurocalcin delta, [Score=194, Expect=4e-63]; ENSG00000115756, HPCAL1, hippocalcin like 1, [Score=191, Expect=1e-61]; ENSG00000121905, HPCA, hippocalcin, [Score=185, Expect=1e-59]} {Mouse: ENSMUSG00000051359, Ncald, neurocalcin delta, [Score=194, Expect=2e-63]; ENSMUSG00000071379, Hpcal1, hippocalcin-like 1, [Score=191, Expect=8e-62]; ENSMUSG00000028785, Hpca, hippocalcin, [Score=185, Expect=1e-59]} {Dmel: FBgn0036926, CG7646, [RH, Score=221, Expect=6e-74]} {Celegans: WBGene00003564, ncs-2, Neuronal calcium sensor 2, [Score=238, Expect=6e-81]} {Smed: dd_Smed_v6_5266_0_1, dd_Smed_v6_5266_0_1, [RH, Score=359, Expect=8e-129]} {RNA1509_13995, RNA1509_14564, RNA1509_30926} {RNA1310_18405, RNA1509_13995, RNA1509_30926} {RNA1509_13995, RNA1509_30926, RNA815_10180.1}
74. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 1.683 - - - 0.718 0.965 - Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
75. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 1.678 - - - 0.720 0.958 -

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
76. MligTC455_42820 154 3.21 Mlig455_029557

Neo: -

Age: -

LARGE1 1.678 - - - 0.726 0.952 - Mlig455_029557 {REF} {Length: 1795} {Pfam: Glycosyl-transferase for dystroglycan [PF13896.8, score=135.5]} {Human: ENSG00000133424, LARGE1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=4e-82]} {Mouse: ENSMUSG00000004383, Large1, LARGE xylosyl- and glucuronyltransferase 1, [Score=262, Expect=8e-82]; ENSMUSG00000040434, Large2, LARGE xylosyl- and glucuronyltransferase 2, [Score=258, Expect=4e-81]} {Dmel: FBgn0032457, CG15483, [Score=62.8, Expect=7e-11]} {Celegans: WBGene00010716, lge-1, Glycosyltransferase-like protein LARGE, [Score=127, Expect=5e-33]} {Smed: dd_Smed_v6_15269_0_1, dd_Smed_v6_15269_0_1, [Score=290, Expect=2e-95]} {RNA1509_47482} {RNA1310_56850.2} {RNA815_37190}
77. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 1.672 - - - 0.706 0.966 - Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
78. MligTC455_46780 396 8.26 Mlig455_044008

Neo: -

Age: Up-Down-Down

1.669 - 0.964 - - - 0.705 Mlig455_044008 {REF} {Length: 5261} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=28.9]} {Dmel: FBgn0034420, CG10737, [RH, Score=70.9, Expect=4e-12]} {Smed: dd_Smed_v6_6358_0_1, dd_Smed_v6_6358_0_1, [Score=55.1, Expect=1e-07]} {RNA1509_17372} {RNA1310_6655, RNA1509_17372} {RNA1509_17372, RNA815_21591}
79. MligTC455_33131 549 11.45 Mlig455_022594, Mlig455_026005, Mlig455_070429

Neo: Germline

Age: logFC(26M/2M)=-0.432

KY 1.667 - - - - 0.961 0.706

Mlig455_022594 {REF} {Length: 667} {Pfam: Helix-turn-helix domain of transposase family ISL3 [PF13542.8, score=27.8]} {RNA1509_53064} {RNA1310_18119} {RNA815_4493}

Mlig455_026005 {REF} {Length: 5002} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=95.5, Expect=1e-19]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=111, Expect=1e-24]} {RNA1509_11170} {RNA1310_2597.1} {RNA815_17158}

Mlig455_070429 {REF} {Length: 5697} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=25.4]} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=97.4, Expect=5e-20]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=96.7, Expect=6e-20]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=113, Expect=4e-25]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=113, Expect=3e-25]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=113, Expect=4e-25]} {RNA1509_11170, RNA1509_29877} {RNA1310_2597.1, RNA1509_11170, RNA1509_29877} {RNA1509_11170, RNA1509_29877, RNA815_3609}
80. MligTC455_35441 205 4.26 Mlig455_009271

Neo: -

Age: -

1.664 - - 0.714 - 0.950 - Mlig455_009271 {REF} {Length: 2810} {Pfam: Acyltransferase family [PF01757.24, score=99.8]; Nose resistant-to-fluoxetine protein, N-terminal domain [PF20146.1, score=67.2]} {Mouse: ENSMUSG00000046610, Oacyl, O-acyltransferase like, [Score=169, Expect=1e-43]} {Dmel: FBgn0052645, CG32645, [Score=254, Expect=3e-72]} {Celegans: WBGene00007833, oac-6, O-ACyltransferase homolog, [RH, Score=234, Expect=3e-66]} {RNA1509_19999} {RNA1310_7490.1} {RNA815_17892}
81. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 1.663 - - - - 0.956 0.707 Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
82. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

1.662 - - - - 0.956 0.706 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
83. MligTC455_52356 37 0.76 Mlig455_042513

Neo: -

Age: -

1.656 - - - - 0.951 0.705 Mlig455_042513 {REF} {Length: 755} {NoTransDecoderORF}
84. MligTC455_25416 74 1.53 Mlig455_023019, Mlig455_023116

Neo: -

Age: -

KCNK18 0.993 - - - - 0.993 -

Mlig455_023019 {REF} {Length: 2752} {Pfam: Ion channel [PF07885.18, score=122.1]; Sodium ion transport-associated [PF06512.15, score=20.3]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=100, Expect=1e-22]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=106, Expect=8e-25]} {Dmel: FBgn0033257, sand, sandman, [Score=147, Expect=1e-39]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=157, Expect=1e-43]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=323, Expect=4e-107]} {RNA1509_41017} {RNA1310_13859.1} {RNA815_18063}

Mlig455_023116 {REF} {Length: 3009} {Pfam: Ion channel [PF07885.18, score=122.1]; Sodium ion transport-associated [PF06512.15, score=19.2]} {Human: ENSG00000186795, KCNK18, potassium two pore domain channel subfamily K member 18, [Score=100, Expect=2e-22]; ENSG00000164626, KCNK5, potassium two pore domain channel subfamily K member 5, [Score=95.1, Expect=2e-20]} {Mouse: ENSMUSG00000040901, Kcnk18, potassium channel, subfamily K, member 18, [Score=106, Expect=1e-24]} {Dmel: FBgn0033257, sand, sandman, [Score=149, Expect=3e-40]} {Celegans: WBGene00010784, twk-48, TWiK family of potassium channels, [Score=159, Expect=4e-44]} {Smed: dd_Smed_v6_17586_0_1, dd_Smed_v6_17586_0_1, [Score=325, Expect=1e-107]} {RNA1509_41017} {RNA1310_13859.1, RNA1509_41017} {RNA1509_41017, RNA815_18063}
85. MligTC455_32003 65 1.35 Mlig455_033440

Neo: -

Age: Up-Down-Down

C20orf27 0.991 - - - - 0.991 - Mlig455_033440 {REF} {Length: 4177} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4517) [PF15006.8, score=120.4]} {Human: ENSG00000101220, C20orf27, chromosome 20 open reading frame 27, [Score=61.2, Expect=2e-11]} {Mouse: ENSMUSG00000027327, 1700037H04Rik, RIKEN cDNA 1700037H04 gene, [Score=62.4, Expect=5e-12]} {Dmel: FBgn0035896, CG6983, [Score=74.3, Expect=1e-16]} {RNA1310_43134} {RNA815_7013}
86. MligTC455_52092 37 0.76 Mlig455_025474

Neo: -

Age: -

0.989 - - - - 0.989 - Mlig455_025474 {REF} {Length: 901} {Pfam: Pancreatic hormone peptide [PF00159.20, score=19.5]} {RNA1509_56567} {RNA1310_46347} {RNA815_35686}
87. MligTC455_45735 175 3.64 Mlig455_013937, Mlig455_039355

Neo: -

Age: Up-Down-Down

0.985 - - - - 0.985 -

Mlig455_013937 {REF} {Length: 1369} {RNA1310_48389} {RNA815_22666}

Mlig455_039355 {REF} {Length: 1299} {RNA1310_48389} {RNA815_22666}
88. MligTC455_46429 48 1 Mlig455_042128

Neo: -

Age: -

0.984 - - - - 0.984 - Mlig455_042128 {REF} {Length: 1428} {Pfam: F5/8 type C domain [PF00754.27, score=33.1]} {RNA1310_65361} {RNA815_33677}
89. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

0.981 - - - - 0.981 - Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
90. MligTC455_15859 120 2.49 Mlig455_007414, Mlig455_067681

Neo: -

Age: -

0.979 - - - - 0.979 -

Mlig455_007414 {REF} {Length: 914} {RNA1310_61579} {RNA815_24378}

Mlig455_067681 {REF} {Length: 917} {RNA1310_61579} {RNA815_24378}
91. MligTC455_18403 11 0.24 Mlig455_059039

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_059039 {REF} {Length: 1516} {NoTransDecoderORF} {RNA1509_38113} {RNA1310_56484.1} {RNA815_14295}
92. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 0.979 - - - - 0.979 - Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
93. MligTC455_42170 342 7.12 Mlig455_038315

Neo: -

Age: Down-Up-Up

0.979 - - - - 0.979 - Mlig455_038315 {REF} {Length: 2851} {Pfam: Innexin [PF00876.20, score=296.2]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=95.5, Expect=5e-21]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=208, Expect=6e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=276, Expect=2e-87]} {RNA1509_10527, RNA1509_45409} {RNA1310_14408, RNA1509_10527, RNA1509_45409} {RNA1509_10527, RNA1509_45409, RNA815_844.2}
94. MligTC455_52656 121 2.51 Mlig455_062381, Mlig455_062408

Neo: -

Age: Down-Up-Down

0.977 - - - - 0.977 -

Mlig455_062381 {REF} {Length: 2245} {RNA1310_26272} {RNA815_22826}

Mlig455_062408 {REF} {Length: 2277} {RNA1310_26272} {RNA815_37592}
95. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

0.976 - - - - 0.976 - Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
96. MligTC455_50434 13 0.26 Mlig455_031234

Neo: -

Age: -

0.976 - - - - 0.976 - Mlig455_031234 {REF} {Length: 1570} {NoTransDecoderORF} {RNA1310_123268} {RNA815_50605}
97. MligTC455_07408 20 0.43 Mlig455_050724

Neo: -

Age: -

0.974 - - - - 0.974 - Mlig455_050724 {REF} {Length: 1796} {RNA1310_65416}
98. MligTC455_23160 221 4.6 Mlig455_007976, Mlig455_015599

Neo: -

Age: logFC(26M/2M)=-0.423

Regeneration-depleted R3: -7.499
Regeneration-depleted R2: -7.172
Regeneration-depleted R4: -6.289
Regeneration-depleted R5: -6.133

0.973 - 0.973 - - - -

Mlig455_007976 {REF} {Length: 1345} {RNA1509_26396} {RNA1310_29311} {RNA815_12314}

Mlig455_015599 {REF} {Length: 1366} {RNA1509_26396} {RNA1310_20007.1, RNA1509_26396} {RNA1509_26396, RNA815_12314}
99. MligTC455_50567 146 3.04 Mlig455_012858

Neo: -

Age: -

Region-specific R2: 6.162

Region-enriched R2: 5.988/0.01054

0.972 - - - - 0.972 - Mlig455_012858 {REF} {Length: 1282} {Pfam: F5/8 type C domain [PF00754.27, score=27.5]} {Smed: dd_Smed_v6_36585_0_1, dd_Smed_v6_36585_0_1, [RH, Score=64.3, Expect=4e-12]} {RNA1310_34633} {RNA815_12537}
100. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 0.971 - - - - 0.971 - Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}

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