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Results for MligTC455_10015

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_10015 1301 27.10 Mlig455_054875

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.120/0.00000
Region-enriched R4: 1.638/0.00586

CYP2C8 Mlig455_054875 {REF} {Length: 2242} {Pfam: Cytochrome P450 [PF00067.24, score=314.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=241, Expect=3e-73]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=236, Expect=8e-71]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=233, Expect=2e-70]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=233, Expect=2e-70]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=241, Expect=2e-73]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=235, Expect=4e-71]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=234, Expect=1e-70]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=233, Expect=2e-70]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=232, Expect=5e-70]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=230, Expect=4e-69]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=229, Expect=9e-69]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=229, Expect=6e-69]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=201, Expect=7e-58]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=222, Expect=1e-66]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=206, Expect=2e-60]} {RNA1509_10048, RNA1509_26828} {RNA1310_15951, RNA1509_10048, RNA1509_26828} {RNA1509_10048, RNA1509_26828, RNA815_5705}

Cumulative graph for MligTC455_10015

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.02 4.958 0.02342 0.41210
RegionR2 -1.729 4.958 0.01657 0.13679
RegionR3 2.12 4.958 0.00000 0.00000
RegionR4 1.638 4.958 0.00049 0.00586
RegionR5 1.002 4.958 0.01031 0.05902
RegionR6 0.196 4.958 0.65729 1.00000
RegionR7 -1.576 4.958 0.05176 0.43779
RegionR8 -3.671 4.958 0.00375 0.10724

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.307 4.958 0.75468 1.00000
RegenerationR2 0.754 4.958 0.12596 0.54863
RegenerationR3 0.262 4.958 0.50755 0.85976
RegenerationR4 0.724 4.958 0.09843 0.48669
RegenerationR5 0.714 4.958 0.06999 0.41543
RegenerationR6 1.179 4.958 0.00771 0.10739
RegenerationBL 1.159 4.958 0.12627 0.42226
RegenerationTP 1.58 4.958 0.11461 0.51856


Genes with expression patterns similar to MligTC455_10015

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_10015 1301 27.1 Mlig455_054875

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.120/0.00000
Region-enriched R4: 1.638/0.00586

CYP2C8 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_054875 {REF} {Length: 2242} {Pfam: Cytochrome P450 [PF00067.24, score=314.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=241, Expect=3e-73]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=236, Expect=8e-71]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=233, Expect=2e-70]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=233, Expect=2e-70]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=241, Expect=2e-73]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=235, Expect=4e-71]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=234, Expect=1e-70]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=233, Expect=2e-70]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=232, Expect=5e-70]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=230, Expect=4e-69]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=229, Expect=9e-69]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=229, Expect=6e-69]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=201, Expect=7e-58]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=222, Expect=1e-66]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=206, Expect=2e-60]} {RNA1509_10048, RNA1509_26828} {RNA1310_15951, RNA1509_10048, RNA1509_26828} {RNA1509_10048, RNA1509_26828, RNA815_5705}
2. MligTC455_38724 5697 118.69 Mlig455_045051

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R3: 1.948/0.00202

PANK4 5.239 0.827 0.798 0.727 0.955 0.955 0.977 Mlig455_045051 {REF} {Length: 2009} {Pfam: Fumble [PF03630.16, score=127.5]} {Human: ENSG00000157881, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]; ENSG00000273494, PANK4, pantothenate kinase 4, [Score=112, Expect=2e-26]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=102, Expect=2e-23]} {Dmel: FBgn0011205, fbl, fumble, [Score=86.7, Expect=1e-18]} {Celegans: WBGene00004068, pnk-1, PaNtothenate Kinase, [Score=82.4, Expect=3e-17]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [RH, Score=225, Expect=1e-70]} {RNA1509_11373, RNA1509_768} {RNA1310_14353, RNA1509_11373} {RNA1509_11373, RNA815_1414}
3. MligTC455_21829 5023 104.65 Mlig455_014094

Neo: -

Age: -

Region-enriched R4: 1.409/0.02548
Region-enriched R3: 1.341/0.03362

5.066 0.713 0.781 0.808 0.965 0.861 0.938 Mlig455_014094 {REF} {Length: 3099} {Pfam: Ependymin [PF00811.20, score=62.5]} {RNA1509_29432} {RNA1310_26645, RNA1509_29432} {RNA1509_29432, RNA815_4988.2}
4. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 5.04 0.799 0.828 0.742 0.970 0.842 0.859 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
5. MligTC455_21830 5295 110.31 Mlig455_014095

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.481

Region-enriched R3: 1.429/0.00231
Region-enriched R4: 1.366/0.01008
Region-enriched R5: 1.005/0.03133

YDJC 5.038 0.701 0.831 0.728 0.981 0.835 0.962 Mlig455_014095 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: YdjC-like protein [PF04794.14, score=165.2]} {Human: ENSG00000161179, YDJC, YdjC chitooligosaccharide deacetylase homolog, [RH, Score=164, Expect=2e-47]} {Mouse: ENSMUSG00000041774, Ydjc, YdjC homolog (bacterial), [RH, Score=172, Expect=7e-51]} {Smed: dd_Smed_v6_65631_0_1, dd_Smed_v6_65631_0_1, [RH, Score=68.9, Expect=2e-14]} {RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1310_36996, RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1509_18855, RNA1509_29693, RNA1509_42768, RNA815_4988.1}
6. MligTC455_32555 3333 69.45 Mlig455_023825

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.526

Region-enriched R3: 1.882/0.00000
Region-enriched R4: 1.126/0.03622

PRSS12 4.58 - 0.927 0.817 0.954 0.921 0.961 Mlig455_023825 {REF} {Length: 4714} {Pfam: Trypsin [PF00089.28, score=216.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=95.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=94.1]; Scavenger receptor cysteine-rich domain [PF15494.8, score=25.1]; Trypsin-like peptidase domain [PF13365.8, score=20.3]; Nematode trypsin-6-like family [PF03761.17, score=18.5]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=220, Expect=4e-60]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=212, Expect=3e-58]} {Dmel: FBgn0023479, teq, Tequila, [Score=286, Expect=1e-81]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [RH, Score=191, Expect=2e-50]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=489, Expect=7e-158]} {RNA1509_337} {RNA1310_1502.2} {RNA815_422}
7. MligTC455_22665 6992 145.67 Mlig455_034131

Neo: -

Age: -

Region-enriched R3: 2.453/0.00000
Region-enriched R5: 1.399/0.00383
Region-enriched R4: 1.286/0.03665

ACE 4.488 0.837 0.891 - 0.941 0.867 0.952 Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600}
8. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

CLCA1 4.386 0.821 0.876 - 0.962 0.888 0.839 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
9. MligTC455_27541 1613 33.6 Mlig455_050579

Neo: -

Age: logFC(26M/2M)=0.592

Region-enriched R3: 2.383/0.00000
Region-enriched R4: 1.941/0.00031
Region-enriched R5: 1.306/0.00531

ACHE 4.364 0.789 0.864 - 0.943 0.813 0.955 Mlig455_050579 {REF} {Length: 4445} {Pfam: Carboxylesterase family [PF00135.30, score=452.6]; alpha/beta hydrolase fold [PF07859.15, score=30.5]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=194, Expect=2e-51]; ENSG00000114200, BCHE, butyrylcholinesterase, [Score=192, Expect=3e-51]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [Score=191, Expect=9e-51]; ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=182, Expect=6e-48]} {Dmel: FBgn0032131, CG3841, [RH, Score=170, Expect=4e-44]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=164, Expect=4e-42]} {Smed: dd_Smed_v6_14790_0_1, dd_Smed_v6_14790_0_1, [Score=155, Expect=4e-39]} {RNA1509_43749} {RNA1310_6417, RNA1509_43749} {RNA1509_43749, RNA815_8474.1}
10. MligTC455_27540 1669 34.76 Mlig455_050550

Neo: -

Age: logFC(26M/2M)=0.741

Region-enriched R3: 2.399/0.00000
Region-enriched R4: 1.902/0.00065
Region-enriched R5: 1.309/0.00668

4.351 0.783 0.863 - 0.938 0.813 0.954 Mlig455_050550 {REF} {Length: 2834} {RNA1509_43749, RNA1509_45402} {RNA1310_6417, RNA1509_45402} {RNA1509_45402, RNA815_8474.1}
11. MligTC455_27625 5733 119.44 Mlig455_018765

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.886/0.00051

MATN2 4.348 0.795 0.854 - 0.964 0.862 0.873 Mlig455_018765 {REF} {Length: 2544} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=97.1, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_3165} {RNA1310_8996, RNA1509_3165} {RNA1509_3165, RNA815_2915.1}
12. MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

CYP2J2 4.319 0.709 0.859 - 0.964 0.861 0.926 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}
13. MligTC455_39169 881 18.35 Mlig455_063890

Neo: -

Age: -

Region-enriched R3: 3.017/0.00000

ALDH2 4.292 0.866 0.871 - 0.967 0.748 0.840 Mlig455_063890 {REF} {Length: 2688} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=591.3]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=777, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1186, RNA1509_20297} {RNA1310_3799.1, RNA1509_20297} {RNA1509_20297, RNA815_1286.1}
14. MligTC455_45315 4773 99.43 Mlig455_037736

Neo: -

Age: -

4.259 - 0.834 0.825 0.950 0.771 0.879 Mlig455_037736 {REF} {Length: 2269} {RNA1509_18494, RNA1509_5801} {RNA1310_12524.1, RNA1509_5801} {RNA1509_5801, RNA815_3944.1}
15. MligTC455_20205 1866 38.88 Mlig455_034438

Neo: -

Age: logFC(26M/2M)=0.508

Region-enriched R4: 1.387/0.03003

4.062 0.740 0.781 - 0.967 0.747 0.827 Mlig455_034438 {REF} {Length: 837} {RNA1509_15789, RNA1509_50882} {RNA1310_45627.1, RNA1509_15789, RNA1509_50882} {RNA1509_15789, RNA1509_50882, RNA815_4285}
16. MligTC455_28793 5084 105.92 Mlig455_060183

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.494

Region-enriched R3: 1.548/0.02653

MUC5B 3.599 - 0.801 - 0.939 0.881 0.978 Mlig455_060183 {REF} {Length: 13150} {Pfam: Mucin-2 protein WxxW repeating region [PF13330.8, score=446.8]; von Willebrand factor type D domain [PF00094.27, score=233.8]; C8 domain [PF08742.13, score=102.9]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=57.0]; F5/8 type C domain [PF00754.27, score=50.9]} {Human: ENSG00000117983, MUC5B, mucin 5B, oligomeric mucus/gel-forming, [RH, Score=593, Expect=7e-169]; ENSG00000215182, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]; ENSG00000283158, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]} {Mouse: ENSMUSG00000066108, Muc5b, mucin 5, subtype B, tracheobronchial, [RH, Score=545, Expect=1e-154]} {Dmel: FBgn0029167, Hml, Hemolectin, [RH, Score=512, Expect=6e-145]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=68.6, Expect=2e-10]} {Smed: dd_Smed_v6_17988_0_1, dd_Smed_v6_17988_0_1, [Score=439, Expect=1e-123]} {RNA1509_4763} {RNA1310_151.1} {RNA815_89.1}
17. MligTC455_24084 9162 190.87 Mlig455_068331

Neo: -

Age: logFC(26M/2M)=0.316

Region-enriched R3: 1.883/0.00000

ACHE 3.577 0.833 - - 0.916 0.876 0.952 Mlig455_068331 {REF} {Length: 2518} {Pfam: Carboxylesterase family [PF00135.30, score=356.7]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=237, Expect=7e-69]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=227, Expect=2e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=196, Expect=4e-54]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=4e-66]} {Smed: dd_Smed_v6_4800_0_2, dd_Smed_v6_4800_0_2, [Score=183, Expect=1e-49]} {RNA1509_18646, RNA1509_195, RNA1509_28401} {RNA1310_9229, RNA1509_18646, RNA1509_195, RNA1509_28401} {RNA1509_18646, RNA1509_195, RNA1509_28401, RNA815_3141.1}
18. MligTC455_39170 3221 67.1 Mlig455_038903

Neo: -

Age: logFC(26M/2M)=0.340

Region-enriched R3: 2.495/0.00000
Region-enriched R4: 1.609/0.00501
Region-enriched R5: 1.221/0.00810

ALDH2 3.566 - 0.852 - 0.966 0.929 0.819 Mlig455_038903 {REF} {Length: 2307} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=593.4]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=780, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=725, Expect=0.0]} {RNA1509_1186} {RNA1310_3799.1} {RNA815_1286.1}
19. MligTC455_45589 8445 175.93 Mlig455_060231

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.105/0.00005

MRC1 3.55 0.828 - - 0.956 0.856 0.910 Mlig455_060231 {REF} {Length: 6599} {Pfam: Lectin C-type domain [PF00059.23, score=668.9]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=86.8]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=514, Expect=1e-153]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=487, Expect=3e-144]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=2e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=207, Expect=7e-54]} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1310_579, RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870} {RNA1509_14934, RNA1509_169, RNA1509_3659, RNA1509_3870, RNA815_112.1}
20. MligTC455_35632 6861 142.93 Mlig455_047206

Neo: -

Age: -

Region-enriched R3: 1.984/0.00032
Region-enriched R4: 1.605/0.01274
Region-enriched R5: 1.441/0.00908

DHDH 3.534 - - 0.729 0.972 0.875 0.958 Mlig455_047206 {REF} {Length: 1483} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=86.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=245, Expect=8e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=247, Expect=1e-79]} {Dmel: FBgn0031418, CG3609, [Score=229, Expect=5e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=211, Expect=2e-66]} {RNA1509_4889} {RNA1310_24236} {RNA815_11111.1}
21. MligTC455_20444 5921 123.36 Mlig455_013875, Mlig455_057736

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.237

Region-enriched R3: 2.359/0.00002
Region-enriched R6: 1.676/0.02373

3.518 0.883 - - 0.951 0.825 0.859

Mlig455_013875 {REF} {Length: 2747} {RNA1509_1235, RNA1509_2361} {RNA1310_8447, RNA1509_1235} {RNA1509_1235, RNA815_3332.1}

Mlig455_057736 {REF} {Length: 2529} {TRANSSPLICED} {RNA1509_11623, RNA1509_2361, RNA1509_37259} {RNA1310_8447, RNA1509_11623, RNA1509_2361, RNA1509_37259} {RNA1509_11623, RNA1509_2361, RNA1509_37259, RNA815_3332.1}
22. MligTC455_45316 4463 92.97 Mlig455_037805

Neo: -

Age: -

3.497 - 0.829 - 0.763 0.913 0.992 Mlig455_037805 {REF} {Length: 2283} {RNA1509_18494} {RNA1310_12524.1, RNA1509_18494} {RNA1509_18494, RNA815_3944.1}
23. MligTC455_31827 5047 105.14 Mlig455_047227, Mlig455_047295

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.850/0.00112
Region-enriched R4: 1.750/0.00523
Region-enriched R5: 1.376/0.01271

3.465 0.770 - - 0.962 0.895 0.838

Mlig455_047227 {REF} {Length: 2245} {Pfam: VDE lipocalin domain [PF07137.13, score=62.5]} {RNA1509_13014, RNA1509_14776} {RNA1310_14334.1, RNA1509_14776} {RNA1509_14776, RNA815_7820}

Mlig455_047295 {REF} {Length: 2123} {Pfam: VDE lipocalin domain [PF07137.13, score=57.7]} {RNA1509_13014} {RNA1310_14334.1, RNA1509_13014} {RNA1509_13014, RNA815_7820}
24. MligTC455_53877 1399 29.15 Mlig455_016664

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R3: 1.947/0.00083
Region-enriched R4: 1.666/0.01644

CLCA1 3.456 0.791 - - 0.987 0.794 0.884 Mlig455_016664 {REF} {Length: 4164} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=169.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=4e-43]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=163, Expect=2e-42]} {RNA1509_1021} {RNA1310_5461.1} {RNA815_1665}
25. MligTC455_18866 706 14.71 Mlig455_027285

Neo: -

Age: Down-Up-Down

3.413 - 0.711 - 0.970 0.830 0.902 Mlig455_027285 {REF} {Length: 736} {RNA1509_12836} {RNA1310_17576.2} {RNA815_6182.1}
26. MligTC455_14370 943 19.64 Mlig455_063547

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-2.337

Region-enriched R4: 2.732/0.00256
Region-enriched R5: 2.309/0.00365
Region-enriched R3: 2.214/0.02131

CYP2C8 3.412 0.711 - 0.900 - 0.848 0.953 Mlig455_063547 {REF} {Length: 1886} {Pfam: Cytochrome P450 [PF00067.24, score=279.9]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=262, Expect=2e-81]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=256, Expect=6e-79]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=249, Expect=3e-76]} {Mouse: ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=259, Expect=2e-80]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=258, Expect=4e-80]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [Score=258, Expect=6e-80]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [Score=255, Expect=7e-79]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=253, Expect=4e-78]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=252, Expect=2e-77]; ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=252, Expect=2e-77]; ENSMUSG00000074254, Cyp2a4, cytochrome P450, family 2, subfamily a, polypeptide 4, [Score=252, Expect=1e-77]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [Score=251, Expect=3e-77]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=251, Expect=3e-77]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [Score=249, Expect=1e-76]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=249, Expect=2e-76]; ENSMUSG00000049685, Cyp2g1, cytochrome P450, family 2, subfamily g, polypeptide 1, [Score=248, Expect=7e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=6e-76]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=248, Expect=5e-76]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=247, Expect=1e-75]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=202, Expect=2e-58]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [Score=215, Expect=1e-63]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=263, Expect=6e-82]} {RNA1509_20560} {RNA1310_19381, RNA1509_20560} {RNA1509_20560, RNA815_15513}
27. MligTC455_20464 3164 65.93 Mlig455_036496, Mlig455_056384

Neo: -

Age: -

Region-enriched R3: 1.967/0.00269
Region-enriched R4: 1.871/0.00861

RAB35 3.388 0.767 - - 0.818 0.842 0.961

Mlig455_036496 {REF} {Length: 1520} {Pfam: Ras family [PF00071.24, score=127.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=49.9]; RsgA GTPase [PF03193.18, score=37.9]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=5e-28]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=8e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=8e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=146, Expect=4e-44]} {RNA1509_21258} {RNA1310_21310.1} {RNA815_8782.1}

Mlig455_056384 {REF} {Length: 1510} {Pfam: Ras family [PF00071.24, score=127.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=51.7]; RsgA GTPase [PF03193.18, score=37.8]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.6]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=4e-28]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=105, Expect=2e-27]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=6e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=7e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=147, Expect=4e-44]} {RNA1509_12602, RNA1509_21258} {RNA1310_21310.1, RNA1509_12602, RNA1509_21258} {RNA1509_12602, RNA1509_21258, RNA815_8782.1}
28. MligTC455_41128 4278 89.13 Mlig455_060924, Mlig455_060990

Neo: -

Age: Down-Up-Up

Region-enriched R3: 2.593/0.00000
Region-enriched R4: 1.399/0.00997

LITAF 3.352 0.761 0.815 - - 0.825 0.951

Mlig455_060924 {REF} {Length: 847} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=79.2]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [Score=88.2, Expect=6e-23]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=92.4, Expect=9e-25]} {Dmel: FBgn0052280, CG32280, [Score=68.9, Expect=5e-16]} {Celegans: WBGene00009484, F36G3.3, [Score=72.4, Expect=3e-17]} {Smed: dd_Smed_v6_353_0_1, dd_Smed_v6_353_0_1, [Score=77.8, Expect=1e-19]} {RNA1509_4677} {RNA1310_51939} {RNA815_17980.1}

Mlig455_060990 {REF} {Length: 851} {Pfam: LITAF-like zinc ribbon domain [PF10601.11, score=79.2]} {Human: ENSG00000189067, LITAF, lipopolysaccharide induced TNF factor, [Score=88.2, Expect=6e-23]} {Mouse: ENSMUSG00000022500, Litaf, LPS-induced TN factor, [Score=92.4, Expect=9e-25]} {Dmel: FBgn0052280, CG32280, [Score=68.9, Expect=5e-16]} {Celegans: WBGene00009484, F36G3.3, [Score=72.4, Expect=3e-17]} {Smed: dd_Smed_v6_353_0_1, dd_Smed_v6_353_0_1, [Score=77.8, Expect=1e-19]} {RNA1509_36964, RNA1509_37429, RNA1509_4677, RNA1509_51675, RNA1509_8036} {RNA1310_51939, RNA1509_36964, RNA1509_37429, RNA1509_4677, RNA1509_51675, RNA1509_8036} {RNA1509_36964, RNA1509_37429, RNA1509_4677, RNA1509_51675, RNA1509_8036, RNA815_17980.1}
29. MligTC455_21474 27672 576.49 Mlig455_064180

Neo: -

Age: -

Region-enriched R3: 1.810/0.00061

CTSV 3.305 0.802 0.712 - 0.960 - 0.831 Mlig455_064180 {REF} {Length: 1968} {Pfam: Papain family cysteine protease [PF00112.25, score=291.7]; Cathepsin propeptide inhibitor domain (I29) [PF08246.14, score=54.9]; Peptidase C1-like family [PF03051.17, score=27.5]} {Human: ENSG00000136943, CTSV, cathepsin V, [RH, Score=358, Expect=3e-123]; ENSG00000135047, CTSL, cathepsin L, [RH, Score=356, Expect=2e-122]} {Mouse: ENSMUSG00000021477, Ctsl, cathepsin L, [RH, Score=348, Expect=9e-120]; ENSMUSG00000042243, BC051665, cDNA sequence BC051665, [RH, Score=335, Expect=1e-114]; ENSMUSG00000056728, Ctsll3, cathepsin L-like 3, [RH, Score=333, Expect=2e-113]} {Dmel: FBgn0013770, Cp1, Cysteine proteinase-1, [Score=359, Expect=6e-124]} {Celegans: WBGene00000776, cpl-1, CathePsin L family, [RH, Score=336, Expect=6e-115]} {Smed: dd_Smed_v6_48_0_1, dd_Smed_v6_48_0_1, [RH, Score=428, Expect=2e-151]} {RNA1509_124} {RNA1310_16613} {RNA815_7527}
30. MligTC455_45290 2414 50.29 Mlig455_024268

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=8.245

Region-enriched R3: 1.852/0.00444

3.294 0.734 - - 0.739 0.864 0.957 Mlig455_024268 {REF} {Length: 1621} {RNA1509_33791} {RNA1310_2718.1} {RNA815_500}
31. MligTC455_45291 2427 50.57 Mlig455_024270

Neo: -

Age: -

Region-enriched R3: 1.846/0.00333

SUSD2 3.291 0.734 - - 0.737 0.867 0.953 Mlig455_024270 {REF} {Length: 4363} {Pfam: AMOP domain [PF03782.19, score=54.3]; von Willebrand factor type D domain [PF00094.27, score=35.6]; Nidogen-like [PF06119.16, score=28.7]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=120, Expect=4e-27]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [RH, Score=134, Expect=1e-31]} {Dmel: FBgn0051004, mesh, [RH, Score=159, Expect=4e-39]} {RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716} {RNA1310_2718.1, RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716} {RNA1509_10841, RNA1509_1220, RNA1509_24159, RNA1509_25642, RNA1509_33791, RNA1509_46716, RNA815_500}
32. MligTC455_41984 5794 120.71 Mlig455_070257

Neo: -

Age: logFC(26M/2M)=0.384

Region-enriched R3: 1.830/0.00014
Region-enriched R4: 1.696/0.00265
Region-enriched R6: 1.511/0.01084
Region-enriched R5: 1.493/0.00157

BHMT 3.255 0.738 - - 0.747 0.804 0.966 Mlig455_070257 {REF} {Length: 2300} {Pfam: Homocysteine S-methyltransferase [PF02574.18, score=161.5]} {Human: ENSG00000145692, BHMT, betaine--homocysteine S-methyltransferase, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000074768, Bhmt, betaine-homocysteine methyltransferase, [RH, Score=548, Expect=0.0]; ENSMUSG00000069324, Gm5096, predicted gene 5096, [RH, Score=548, Expect=0.0]} {Smed: dd_Smed_v6_873_0_1, dd_Smed_v6_873_0_1, [RH, Score=555, Expect=0.0]} {RNA1509_10637, RNA1509_54311, RNA1509_9980} {RNA1310_18981.1, RNA1509_54311, RNA1509_9980} {RNA1509_54311, RNA1509_9980, RNA815_5900.2}
33. MligTC455_48498 1066 22.21 Mlig455_007871

Neo: -

Age: logFC(26M/2M)=0.286

Region-enriched R3: 1.717/0.03337

MICU3 2.747 - - - 0.962 0.884 0.901 Mlig455_007871 {REF} {Length: 2576} {Pfam: EF-hand domain pair [PF13499.8, score=34.5]; EF-hand domain [PF13405.8, score=34.4]; EF-hand domain pair [PF13833.8, score=32.0]; EF hand [PF00036.34, score=30.6]; EF hand [PF13202.8, score=22.8]} {Human: ENSG00000155970, MICU3, mitochondrial calcium uptake family member 3, [Score=260, Expect=1e-82]} {Mouse: ENSMUSG00000021973, Micu2, mitochondrial calcium uptake 2, [Score=216, Expect=3e-65]; ENSMUSG00000039478, Micu3, mitochondrial calcium uptake family, member 3, [Score=214, Expect=2e-63]} {Dmel: FBgn0038735, CG4662, [Score=282, Expect=3e-90]} {Celegans: WBGene00008345, C56A3.6, [RH, Score=239, Expect=1e-74]} {Smed: dd_Smed_v6_5430_0_1, dd_Smed_v6_5430_0_1, [Score=204, Expect=9e-61]} {RNA1509_14710, RNA1509_26156} {RNA1310_3702, RNA1509_14710, RNA1509_26156} {RNA1509_14710, RNA1509_26156, RNA815_171.2}
34. MligTC455_26632 2223 46.31 Mlig455_010979

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.932

Region-enriched R3: 1.352/0.01651

ASGR2 2.7 0.824 - - 0.950 - 0.926 Mlig455_010979 {REF} {Length: 3718} {Pfam: Lectin C-type domain [PF00059.23, score=51.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=29.4]} {Human: ENSG00000161944, ASGR2, asialoglycoprotein receptor 2, [Score=53.1, Expect=6e-07]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=62.0, Expect=2e-09]; ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=60.5, Expect=6e-09]} {Dmel: FBgn0029697, CG15570, [Score=82.4, Expect=7e-16]} {Celegans: WBGene00020585, clec-178, C-type LECtin, [Score=57.4, Expect=2e-09]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=48.5, Expect=7e-06]} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1310_25013.1, RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412, RNA815_11727}
35. MligTC455_11650 1098 22.87 Mlig455_007133

Neo: -

Age: logFC(26M/2M)=1.455

Region-enriched R4: 2.055/0.00000
Region-enriched R3: 1.617/0.00001
Region-enriched R5: 1.032/0.00532

2.688 - - - 0.957 0.873 0.858 Mlig455_007133 {REF} {Length: 1372} {Pfam: Tyrosine phosphatase family [PF13350.8, score=133.9]; Tyrosine phosphatase family [PF03162.15, score=32.8]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [RH, Score=96.3, Expect=2e-22]} {RNA1509_24412} {RNA1310_29199} {RNA815_14210.1}
36. MligTC455_35666 3073 64.02 Mlig455_024866

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.297

Region-enriched R3: 1.613/0.00014

AC099489.1 2.68 - - - 0.985 0.825 0.870 Mlig455_024866 {REF} {Length: 12799} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=87.8]; Domain of unknown function (DUF1943) [PF09172.13, score=66.5]; von Willebrand factor type D domain [PF00094.27, score=29.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=128, Expect=3e-28]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=67.8, Expect=3e-10]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=94.7, Expect=1e-18]} {RNA1509_27087} {RNA1310_1234.2} {RNA815_55}
37. MligTC455_26853 2844 59.26 Mlig455_045784

Neo: -

Age: -

2.663 - 0.799 - 0.897 - 0.967 Mlig455_045784 {REF} {Length: 1134} {RNA1509_9102} {RNA1310_32519} {RNA815_6130}
38. MligTC455_16017 1654 34.46 Mlig455_052747

Neo: -

Age: -

Region-enriched R4: 1.664/0.00032
Region-enriched R3: 1.084/0.03324

PM20D2 2.612 - 0.823 - 0.836 - 0.953 Mlig455_052747 {REF} {Length: 1787} {TRANSSPLICED} {Pfam: Peptidase dimerisation domain [PF07687.16, score=33.3]; Peptidase family M20/M25/M40 [PF01546.30, score=29.9]} {Human: ENSG00000146281, PM20D2, peptidase M20 domain containing 2, [RH, Score=356, Expect=5e-120]} {Mouse: ENSMUSG00000054659, Pm20d2, peptidase M20 domain containing 2, [RH, Score=355, Expect=1e-119]} {Smed: dd_Smed_v6_7395_0_1, dd_Smed_v6_7395_0_1, [RH, Score=337, Expect=9e-114]} {RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1310_17432.1, RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1509_27696, RNA1509_38773, RNA1509_53331, RNA815_6952}
39. MligTC455_40311 795 16.57 Mlig455_005646

Neo: -

Age: logFC(26M/2M)=-1.077

Region-enriched R4: 2.244/0.00079
Region-enriched R5: 1.789/0.00084

CYP2J2 2.611 - - - 0.971 0.862 0.778 Mlig455_005646 {REF} {Length: 2326} {Pfam: Cytochrome P450 [PF00067.24, score=345.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=303, Expect=4e-97]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=280, Expect=2e-88]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=1e-88]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=278, Expect=3e-87]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=276, Expect=8e-87]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=3e-85]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=271, Expect=1e-84]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=1e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=270, Expect=2e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=223, Expect=5e-66]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=249, Expect=1e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=260, Expect=8e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
40. MligTC455_53724 3456 72 Mlig455_018433

Neo: -

Age: -

Region-enriched R3: 1.982/0.00002
Region-enriched R4: 1.264/0.03136

LCT 2.598 - - - 0.805 0.821 0.972 Mlig455_018433 {REF} {Length: 2252} {Pfam: Glycosyl hydrolase family 1 [PF00232.20, score=486.8]} {Human: ENSG00000115850, LCT, lactase, [Score=398, Expect=3e-123]; ENSG00000188501, LCTL, lactase like, [Score=381, Expect=3e-126]} {Mouse: ENSMUSG00000026354, Lct, lactase, [Score=392, Expect=4e-121]; ENSMUSG00000032401, Lctl, lactase-like, [Score=373, Expect=2e-123]} {Dmel: FBgn0036659, CG9701, [Score=362, Expect=1e-119]} {Celegans: WBGene00016848, klo-1, KLOtho (Mammalian aging-associated protein) homolog, [Score=290, Expect=1e-92]} {RNA1509_43625, RNA1509_50349, RNA1509_58520} {RNA1310_27605, RNA1509_50349, RNA1509_58520} {RNA1509_50349, RNA1509_58520, RNA815_3875.2}
41. MligTC455_43333 11678 243.29 Mlig455_036055

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.186

Region-enriched R3: 1.916/0.00004
Region-enriched R6: 1.435/0.01562
Region-enriched R5: 1.079/0.03201

CTSB 2.586 0.746 - - 0.950 - 0.890 Mlig455_036055 {REF} {Length: 1907} {Pfam: Papain family cysteine protease [PF00112.25, score=227.2]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=388, Expect=7e-135]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=385, Expect=5e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=366, Expect=1e-126]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=336, Expect=1e-114]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=427, Expect=2e-150]} {RNA1509_2988, RNA1509_448} {RNA1310_24539, RNA1509_2988} {RNA1509_2988, RNA815_4531}
42. MligTC455_50034 2671 55.65 Mlig455_000005

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.540

Region-enriched R3: 1.249/0.00057

SPHK1 2.558 - - - 0.970 0.787 0.801 Mlig455_000005 {REF} {Length: 2212} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=70.4]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=144, Expect=1e-37]} {Mouse: ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=140, Expect=1e-35]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=134, Expect=1e-33]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=121, Expect=3e-30]} {RNA1509_19326} {RNA1310_4471, RNA1509_19326} {RNA1509_19326, RNA815_1161}
43. MligTC455_40620 3703 77.15 Mlig455_034547, Mlig455_064817

Neo: -

Age: logFC(26M/2M)=0.348

Region-enriched R3: 1.638/0.00022

SGPL1 2.553 - - - 0.838 0.741 0.974

Mlig455_034547 {REF} {Length: 1975} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=71.4]; Aminotransferase class-V [PF00266.21, score=28.0]} {Human: ENSG00000166224, SGPL1, sphingosine-1-phosphate lyase 1, [Score=313, Expect=1e-99]} {Mouse: ENSMUSG00000020097, Sgpl1, sphingosine phosphate lyase 1, [Score=313, Expect=8e-100]} {Dmel: FBgn0010591, Sply, Sphingosine-1-phosphate lyase, [Score=286, Expect=9e-90]} {Celegans: WBGene00004981, spl-1, Sphingosine-1-phosphate lyase, [Score=283, Expect=2e-88]} {Smed: dd_Smed_v6_4459_0_1, dd_Smed_v6_4459_0_1, [Score=301, Expect=2e-95]} {RNA1509_16302} {RNA1310_14912} {RNA815_7513}

Mlig455_064817 {REF} {Length: 3062} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=73.9]; Aminotransferase class-V [PF00266.21, score=28.0]} {Human: ENSG00000166224, SGPL1, sphingosine-1-phosphate lyase 1, [Score=316, Expect=1e-100]} {Mouse: ENSMUSG00000020097, Sgpl1, sphingosine phosphate lyase 1, [Score=315, Expect=2e-100]} {Dmel: FBgn0010591, Sply, Sphingosine-1-phosphate lyase, [Score=283, Expect=1e-88]} {Celegans: WBGene00004981, spl-1, Sphingosine-1-phosphate lyase, [Score=286, Expect=1e-89]} {Smed: dd_Smed_v6_4459_0_1, dd_Smed_v6_4459_0_1, [Score=301, Expect=1e-95]} {RNA1509_12635, RNA1509_16302} {RNA1310_14912, RNA1509_12635, RNA1509_16302} {RNA1509_12635, RNA1509_16302, RNA815_7513}
44. MligTC455_20260 2212 46.08 Mlig455_009003, Mlig455_016540, Mlig455_016597

Neo: -

Age: -

EPHX1 2.511 - 0.836 - - 0.705 0.970

Mlig455_009003 {REF} {Length: 2659} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=64.9]; Epoxide hydrolase N terminus [PF06441.14, score=52.9]} {Human: ENSG00000143819, EPHX1, epoxide hydrolase 1, [Score=334, Expect=1e-110]} {Mouse: ENSMUSG00000038776, Ephx1, epoxide hydrolase 1, microsomal, [Score=337, Expect=2e-111]} {Dmel: FBgn0034405, Jheh2, Juvenile hormone epoxide hydrolase 2, [Score=284, Expect=3e-91]} {Celegans: WBGene00020909, W01A11.1, Epoxide hydrolase, [Score=316, Expect=6e-104]} {Smed: dd_Smed_v6_5113_0_1, dd_Smed_v6_5113_0_1, [Score=291, Expect=5e-94]} {RNA1509_43717} {RNA1310_12863.2} {RNA815_5223.1}

Mlig455_016540 {REF} {Length: 2059} {Pfam: Epoxide hydrolase N terminus [PF06441.14, score=60.1]} {Human: ENSG00000143819, EPHX1, epoxide hydrolase 1, [Score=80.5, Expect=2e-16]} {Mouse: ENSMUSG00000038776, Ephx1, epoxide hydrolase 1, microsomal, [Score=83.6, Expect=1e-17]} {Dmel: FBgn0010053, Jheh1, Juvenile hormone epoxide hydrolase 1, [Score=89.0, Expect=1e-19]} {Celegans: WBGene00020909, W01A11.1, Epoxide hydrolase, [Score=88.6, Expect=1e-19]} {Smed: dd_Smed_v6_5113_0_1, dd_Smed_v6_5113_0_1, [Score=91.7, Expect=7e-21]} {RNA1509_27745, RNA1509_29348, RNA1509_43717, RNA1509_6714} {RNA1310_12863.1, RNA1509_27745, RNA1509_29348, RNA1509_43717, RNA1509_6714} {RNA1509_27745, RNA1509_29348, RNA1509_43717, RNA1509_6714, RNA815_5223.1}

Mlig455_016597 {REF} {Length: 2370} {Pfam: Epoxide hydrolase N terminus [PF06441.14, score=104.4]; alpha/beta hydrolase fold [PF00561.22, score=64.7]} {Human: ENSG00000143819, EPHX1, epoxide hydrolase 1, [Score=330, Expect=7e-109]} {Mouse: ENSMUSG00000038776, Ephx1, epoxide hydrolase 1, microsomal, [Score=334, Expect=9e-111]} {Dmel: FBgn0034406, Jheh3, Juvenile hormone epoxide hydrolase 3, [Score=291, Expect=8e-94]} {Celegans: WBGene00020909, W01A11.1, Epoxide hydrolase, [Score=319, Expect=3e-105]} {Smed: dd_Smed_v6_5113_0_1, dd_Smed_v6_5113_0_1, [Score=316, Expect=7e-104]} {RNA1509_27745} {RNA1310_12863.2} {RNA815_5223.1}
45. MligTC455_38391 6369 132.68 Mlig455_039832

Neo: -

Age: -

Region-enriched R3: 1.882/0.00306

KREMEN1 2.508 0.718 - - 0.838 - 0.952 Mlig455_039832 {REF} {Length: 3266} {Pfam: WSC domain [PF01822.21, score=64.1]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=55.8, Expect=1e-09]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=53.5, Expect=6e-09]} {Dmel: FBgn0046685, Wsck, [Score=57.8, Expect=1e-10]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=44.7, Expect=4e-06]} {RNA1509_11244, RNA1509_1540, RNA1509_18476, RNA1509_23082, RNA1509_31249, RNA1509_31561, RNA1509_4008, RNA1509_40553} {RNA1310_42554, RNA1509_11244, RNA1509_1540, RNA1509_18476, RNA1509_23082, RNA1509_31249, RNA1509_31561, RNA1509_4008, RNA1509_40553} {RNA1509_11244, RNA1509_1540, RNA1509_18476, RNA1509_23082, RNA1509_31249, RNA1509_31561, RNA1509_4008, RNA1509_40553, RNA815_21733.1}
46. MligTC455_15855 791 16.48 Mlig455_054856

Neo: -

Age: logFC(26M/2M)=0.364

Region-enriched R3: 2.777/0.00002
Region-enriched R4: 2.336/0.00267
Region-enriched R5: 1.838/0.01080

2.482 0.758 0.766 - - 0.958 - Mlig455_054856 {REF} {Length: 4877} {Pfam: Low-density lipoprotein receptor domain class A [PF00057.20, score=54.4]; CUB domain [PF00431.22, score=24.3]} {RNA1509_6900} {RNA1310_4649} {RNA815_2022}
47. MligTC455_50449 2354 49.04 Mlig455_064469

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.266

Region-enriched R3: 1.639/0.00084
Region-enriched R5: 1.149/0.01827

KREMEN1 2.41 0.706 - 0.745 - - 0.959 Mlig455_064469 {REF} {Length: 719} {TRANSSPLICED} {Pfam: WSC domain [PF01822.21, score=61.7]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=52.4, Expect=9e-08]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=50.8, Expect=3e-08]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=53.9, Expect=1e-08]} {RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774, RNA1509_51348} {RNA1310_56240.1, RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774} {RNA1509_25081, RNA1509_3423, RNA1509_43914, RNA1509_47774, RNA815_26405}
48. MligTC455_24363 1243 25.89 Mlig455_065691

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.713

MOGAT2 1.808 - - - 0.953 - 0.855 Mlig455_065691 {REF} {Length: 3352} {TRANSSPLICED} {Pfam: Diacylglycerol acyltransferase [PF03982.15, score=385.5]} {Human: ENSG00000166391, MOGAT2, monoacylglycerol O-acyltransferase 2, [RH, Score=341, Expect=3e-111]; ENSG00000124003, MOGAT1, monoacylglycerol O-acyltransferase 1, [RH, Score=341, Expect=2e-111]} {Mouse: ENSMUSG00000052396, Mogat2, monoacylglycerol O-acyltransferase 2, [RH, Score=343, Expect=2e-112]; ENSMUSG00000012187, Mogat1, monoacylglycerol O-acyltransferase 1, [RH, Score=338, Expect=2e-110]} {Dmel: FBgn0033214, CG1941, [RH, Score=243, Expect=8e-74]} {Celegans: WBGene00019464, K07B1.4, [RH, Score=323, Expect=2e-104]} {Smed: dd_Smed_v6_4947_0_1, dd_Smed_v6_4947_0_1, [RH, Score=395, Expect=7e-133]} {RNA1509_22728} {RNA1310_14435.2} {RNA815_3120.1}
49. MligTC455_42042 5653 117.77 Mlig455_011072

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.324

Region-enriched R3: 1.823/0.00256

1.735 - - - 0.754 - 0.981 Mlig455_011072 {REF} {Length: 901} {Pfam: Lipocalin / cytosolic fatty-acid binding protein family [PF00061.25, score=22.3]; PRELI-like family [PF04707.16, score=19.8]} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1310_48326.1, RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378} {RNA1509_12545, RNA1509_13994, RNA1509_22514, RNA1509_2342, RNA1509_39817, RNA1509_42424, RNA1509_50410, RNA1509_5504, RNA1509_57378, RNA815_23354}
50. MligTC455_43948 3488 72.67 Mlig455_002834, Mlig455_002839

Neo: -

Age: logFC(26M/2M)=-0.402

Region-enriched R5: 1.557/0.01497

SLC32A1 0.974 - - - 0.974 - -

Mlig455_002834 {REF} {Length: 2083} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=180.6]} {Human: ENSG00000101438, SLC32A1, solute carrier family 32 member 1, [Score=183, Expect=6e-51]} {Mouse: ENSMUSG00000037771, Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, [Score=182, Expect=7e-51]} {Dmel: FBgn0033911, VGAT, Vesicular GABA Transporter, [Score=178, Expect=4e-49]} {Celegans: WBGene00006783, unc-47, Vesicular GABA transporter, [Score=189, Expect=6e-54]} {Smed: dd_Smed_v6_20353_0_1, dd_Smed_v6_20353_0_1, [RH, Score=382, Expect=2e-128]} {RNA1509_6347} {RNA1310_11411, RNA1509_6347} {RNA1509_6347, RNA815_4946}

Mlig455_002839 {REF} {Length: 1987} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=180.6]} {Human: ENSG00000101438, SLC32A1, solute carrier family 32 member 1, [Score=183, Expect=6e-51]} {Mouse: ENSMUSG00000037771, Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, [Score=182, Expect=7e-51]} {Dmel: FBgn0033911, VGAT, Vesicular GABA Transporter, [Score=178, Expect=4e-49]} {Celegans: WBGene00006783, unc-47, Vesicular GABA transporter, [Score=189, Expect=6e-54]} {Smed: dd_Smed_v6_20353_0_1, dd_Smed_v6_20353_0_1, [RH, Score=382, Expect=2e-128]} {RNA1509_24687, RNA1509_28188, RNA1509_6347} {RNA1310_11411, RNA1509_24687, RNA1509_28188} {RNA1509_24687, RNA1509_28188, RNA815_4946}
51. MligTC455_20083 602 12.55 Mlig455_017591, Mlig455_058808, Mlig455_058860

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=5.198

Region-enriched R3: 6.259/0.00385

CLCA1 0.968 - - - - - 0.968

Mlig455_017591 {REF} {Length: 3361} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000028262, Clca3a2, chloride channel accessory 3A2, [Score=97.1, Expect=2e-21]; ENSMUSG00000037033, Clca3b, chloride channel accessory 3B, [Score=96.7, Expect=3e-21]; ENSMUSG00000056025, Clca3a1, chloride channel accessory 3A1, [Score=93.6, Expect=2e-20]} {RNA1509_12329} {RNA1310_4907, RNA1509_12329} {RNA1509_12329, RNA815_880.1}

Mlig455_058808 {REF} {Length: 3017} {TRANSSPLICED} {Pfam: von Willebrand factor type A domain [PF00092.30, score=80.2]; Calcium-activated chloride channel N terminal [PF08434.13, score=70.9]; von Willebrand factor type A domain [PF13519.8, score=43.4]; von Willebrand factor type A domain [PF13768.8, score=32.3]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=211, Expect=3e-56]} {Mouse: ENSMUSG00000028262, Clca3a2, chloride channel accessory 3A2, [Score=211, Expect=2e-56]; ENSMUSG00000056025, Clca3a1, chloride channel accessory 3A1, [Score=208, Expect=2e-55]; ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=203, Expect=1e-53]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=132, Expect=2e-31]} {RNA1509_5258} {RNA1310_4907} {RNA815_880.1}

Mlig455_058860 {REF} {Length: 3090} {TRANSSPLICED} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=103.0]; von Willebrand factor type A domain [PF00092.30, score=80.4]; von Willebrand factor type A domain [PF13519.8, score=42.2]; von Willebrand factor type A domain [PF13768.8, score=33.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=224, Expect=1e-60]; ENSG00000016602, CLCA4, chloride channel accessory 4, [Score=214, Expect=3e-57]} {Mouse: ENSMUSG00000028262, Clca3a2, chloride channel accessory 3A2, [RH, Score=234, Expect=4e-64]} {Smed: dd_Smed_v6_3663_0_1, dd_Smed_v6_3663_0_1, [RH, Score=147, Expect=2e-36]} {RNA1509_12329} {RNA1310_4907} {RNA815_880.1}

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