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Results for MligTC455_33836

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

CYP2J2 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}

Cumulative graph for MligTC455_33836

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.259 5.611 0.73485 1.00000
RegionR2 -0.77 5.611 0.10057 0.38984
RegionR3 1.925 5.611 0.00000 0.00000
RegionR4 1.2 5.611 0.00158 0.01490
RegionR5 1.02 5.611 0.00112 0.01114
RegionR6 0.495 5.611 0.16490 0.71953
RegionR7 -2.564 5.611 0.00005 0.00292
RegionR8 -1.566 5.611 0.02374 0.30032

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.15 5.611 0.87957 1.00000
RegenerationR2 0.019 5.611 0.96175 1.00000
RegenerationR3 -0.045 5.611 0.90467 1.00000
RegenerationR4 0.622 5.611 0.12214 0.53179
RegenerationR5 0.518 5.611 0.16273 0.58728
RegenerationR6 0.938 5.611 0.01687 0.16041
RegenerationBL 0.632 5.611 0.23903 0.59278
RegenerationTP 0.368 5.611 0.60092 0.96140


Genes with expression patterns similar to MligTC455_33836

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

CYP2J2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}
2. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

CLCA1 5.132 0.707 0.896 0.834 0.951 0.881 0.863 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
3. MligTC455_24083 6997 145.77 Mlig455_007319

Neo: -

Age: -

Region-enriched R3: 2.037/0.00010
Region-enriched R5: 1.165/0.04106

ACHE 5.13 0.707 0.837 0.796 0.966 0.933 0.891 Mlig455_007319 {REF} {Length: 2399} {Pfam: Carboxylesterase family [PF00135.30, score=344.4]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=233, Expect=9e-68]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=225, Expect=3e-65]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=183, Expect=6e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=228, Expect=1e-66]} {Smed: dd_Smed_v6_4800_0_1, dd_Smed_v6_4800_0_1, [Score=184, Expect=4e-50]} {RNA1509_195, RNA1509_4270, RNA1509_51012} {RNA1310_9229, RNA1509_4270, RNA1509_51012} {RNA1509_4270, RNA1509_51012, RNA815_3141.1}
4. MligTC455_27625 5733 119.44 Mlig455_018765

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.886/0.00051

MATN2 5.089 0.764 0.877 0.784 0.951 0.867 0.846 Mlig455_018765 {REF} {Length: 2544} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=97.1, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_3165} {RNA1310_8996, RNA1509_3165} {RNA1509_3165, RNA815_2915.1}
5. MligTC455_20444 5921 123.36 Mlig455_013875, Mlig455_057736

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.237

Region-enriched R3: 2.359/0.00002
Region-enriched R6: 1.676/0.02373

4.861 0.729 0.711 0.742 0.970 0.807 0.902

Mlig455_013875 {REF} {Length: 2747} {RNA1509_1235, RNA1509_2361} {RNA1310_8447, RNA1509_1235} {RNA1509_1235, RNA815_3332.1}

Mlig455_057736 {REF} {Length: 2529} {TRANSSPLICED} {RNA1509_11623, RNA1509_2361, RNA1509_37259} {RNA1310_8447, RNA1509_11623, RNA1509_2361, RNA1509_37259} {RNA1509_11623, RNA1509_2361, RNA1509_37259, RNA815_3332.1}
6. MligTC455_32555 3333 69.45 Mlig455_023825

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.526

Region-enriched R3: 1.882/0.00000
Region-enriched R4: 1.126/0.03622

PRSS12 4.436 0.797 0.905 - 0.965 0.892 0.877 Mlig455_023825 {REF} {Length: 4714} {Pfam: Trypsin [PF00089.28, score=216.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=95.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=94.1]; Scavenger receptor cysteine-rich domain [PF15494.8, score=25.1]; Trypsin-like peptidase domain [PF13365.8, score=20.3]; Nematode trypsin-6-like family [PF03761.17, score=18.5]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=220, Expect=4e-60]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=212, Expect=3e-58]} {Dmel: FBgn0023479, teq, Tequila, [Score=286, Expect=1e-81]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [RH, Score=191, Expect=2e-50]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=489, Expect=7e-158]} {RNA1509_337} {RNA1310_1502.2} {RNA815_422}
7. MligTC455_22665 6992 145.67 Mlig455_034131

Neo: -

Age: -

Region-enriched R3: 2.453/0.00000
Region-enriched R5: 1.399/0.00383
Region-enriched R4: 1.286/0.03665

ACE 4.427 - 0.930 0.746 0.883 0.897 0.971 Mlig455_034131 {REF} {Length: 2725} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=702.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=523, Expect=3e-171]; ENSG00000264813, AC113554.1, novel transcript, [RH, Score=518, Expect=2e-175]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=526, Expect=6e-172]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [RH, Score=456, Expect=7e-153]} {Smed: dd_Smed_v6_6160_0_1, dd_Smed_v6_6160_0_1, [Score=399, Expect=7e-131]} {RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1310_5722, RNA1509_2364, RNA1509_2955, RNA1509_47766} {RNA1509_2364, RNA1509_2955, RNA1509_47766, RNA815_3600}
8. MligTC455_20619 2288 47.67 Mlig455_055574

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.591/0.00258
Region-enriched R4: 1.303/0.03358

SLC24A5 4.362 0.752 0.900 - 0.957 0.961 0.792 Mlig455_055574 {REF} {Length: 3527} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_4708} {RNA1310_7971.1} {RNA815_7327}
9. MligTC455_28793 5084 105.92 Mlig455_060183

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.494

Region-enriched R3: 1.548/0.02653

MUC5B 4.338 - 0.933 0.783 0.960 0.769 0.893 Mlig455_060183 {REF} {Length: 13150} {Pfam: Mucin-2 protein WxxW repeating region [PF13330.8, score=446.8]; von Willebrand factor type D domain [PF00094.27, score=233.8]; C8 domain [PF08742.13, score=102.9]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=57.0]; F5/8 type C domain [PF00754.27, score=50.9]} {Human: ENSG00000117983, MUC5B, mucin 5B, oligomeric mucus/gel-forming, [RH, Score=593, Expect=7e-169]; ENSG00000215182, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]; ENSG00000283158, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]} {Mouse: ENSMUSG00000066108, Muc5b, mucin 5, subtype B, tracheobronchial, [RH, Score=545, Expect=1e-154]} {Dmel: FBgn0029167, Hml, Hemolectin, [RH, Score=512, Expect=6e-145]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=68.6, Expect=2e-10]} {Smed: dd_Smed_v6_17988_0_1, dd_Smed_v6_17988_0_1, [Score=439, Expect=1e-123]} {RNA1509_4763} {RNA1310_151.1} {RNA815_89.1}
10. MligTC455_10015 1301 27.1 Mlig455_054875

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.120/0.00000
Region-enriched R4: 1.638/0.00586

CYP2C8 4.319 0.709 0.859 - 0.964 0.861 0.926 Mlig455_054875 {REF} {Length: 2242} {Pfam: Cytochrome P450 [PF00067.24, score=314.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=241, Expect=3e-73]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=236, Expect=8e-71]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=233, Expect=2e-70]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=233, Expect=2e-70]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=241, Expect=2e-73]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=235, Expect=4e-71]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=234, Expect=1e-70]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=233, Expect=2e-70]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=232, Expect=5e-70]; ENSMUSG00000005547, Cyp2a5, cytochrome P450, family 2, subfamily a, polypeptide 5, [Score=230, Expect=4e-69]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=229, Expect=9e-69]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=229, Expect=6e-69]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=201, Expect=7e-58]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=222, Expect=1e-66]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=206, Expect=2e-60]} {RNA1509_10048, RNA1509_26828} {RNA1310_15951, RNA1509_10048, RNA1509_26828} {RNA1509_10048, RNA1509_26828, RNA815_5705}
11. MligTC455_21830 5295 110.31 Mlig455_014095

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.481

Region-enriched R3: 1.429/0.00231
Region-enriched R4: 1.366/0.01008
Region-enriched R5: 1.005/0.03133

YDJC 4.296 - 0.781 0.791 0.967 0.835 0.922 Mlig455_014095 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: YdjC-like protein [PF04794.14, score=165.2]} {Human: ENSG00000161179, YDJC, YdjC chitooligosaccharide deacetylase homolog, [RH, Score=164, Expect=2e-47]} {Mouse: ENSMUSG00000041774, Ydjc, YdjC homolog (bacterial), [RH, Score=172, Expect=7e-51]} {Smed: dd_Smed_v6_65631_0_1, dd_Smed_v6_65631_0_1, [RH, Score=68.9, Expect=2e-14]} {RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1310_36996, RNA1509_18855, RNA1509_29693, RNA1509_42768} {RNA1509_18855, RNA1509_29693, RNA1509_42768, RNA815_4988.1}
12. MligTC455_10014 765 15.94 Mlig455_054784

Neo: -

Age: Up-Down-Up

Region-enriched R3: 3.005/0.00000
Region-enriched R4: 2.552/0.00078
Region-enriched R5: 1.682/0.01840

CYP2C8 4.294 - 0.809 0.744 0.957 0.914 0.870 Mlig455_054784 {REF} {Length: 2267} {Pfam: Cytochrome P450 [PF00067.24, score=286.1]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=228, Expect=1e-68]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=221, Expect=2e-65]; ENSG00000255974, CYP2A6, cytochrome P450 family 2 subfamily A member 6, [Score=219, Expect=3e-65]; ENSG00000197838, CYP2A13, cytochrome P450 family 2 subfamily A member 13, [Score=219, Expect=3e-65]} {Mouse: ENSMUSG00000022445, Cyp2d26, cytochrome P450, family 2, subfamily d, polypeptide 26, [Score=229, Expect=8e-69]; ENSMUSG00000091867, Cyp2a22, cytochrome P450, family 2, subfamily a, polypeptide 22, [Score=224, Expect=4e-67]; ENSMUSG00000060407, Cyp2a12, cytochrome P450, family 2, subfamily a, polypeptide 12, [Score=222, Expect=2e-66]; ENSMUSG00000003053, Cyp2c29, cytochrome P450, family 2, subfamily c, polypeptide 29, [Score=221, Expect=5e-66]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=221, Expect=7e-66]; ENSMUSG00000061740, Cyp2d22, cytochrome P450, family 2, subfamily d, polypeptide 22, [Score=218, Expect=1e-64]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=192, Expect=1e-54]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=210, Expect=3e-62]} {Smed: dd_Smed_v6_5344_0_6, dd_Smed_v6_5344_0_6, [Score=199, Expect=7e-58]} {RNA1509_10048} {RNA1310_15951} {RNA815_5705}
13. MligTC455_45590 6933 144.44 Mlig455_060243

Neo: -

Age: Up-Down-Down

Region-enriched R3: 1.918/0.00019

MRC1 4.26 0.710 0.843 0.898 - 0.830 0.979 Mlig455_060243 {REF} {Length: 4769} {Pfam: Lectin C-type domain [PF00059.23, score=548.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=62.0]; Extracellular link domain [PF00193.19, score=22.4]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=513, Expect=2e-156]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=485, Expect=1e-146]} {Dmel: FBgn0035199, tfc, triforce, [Score=57.4, Expect=8e-09]} {Celegans: WBGene00020191, clec-53, C-type LECtin, [RH, Score=103, Expect=1e-23]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=209, Expect=1e-54]} {RNA1509_169} {RNA1310_579} {RNA815_112.1}
14. MligTC455_16017 1654 34.46 Mlig455_052747

Neo: -

Age: -

Region-enriched R4: 1.664/0.00032
Region-enriched R3: 1.084/0.03324

PM20D2 4.254 - 0.886 0.701 0.900 0.814 0.953 Mlig455_052747 {REF} {Length: 1787} {TRANSSPLICED} {Pfam: Peptidase dimerisation domain [PF07687.16, score=33.3]; Peptidase family M20/M25/M40 [PF01546.30, score=29.9]} {Human: ENSG00000146281, PM20D2, peptidase M20 domain containing 2, [RH, Score=356, Expect=5e-120]} {Mouse: ENSMUSG00000054659, Pm20d2, peptidase M20 domain containing 2, [RH, Score=355, Expect=1e-119]} {Smed: dd_Smed_v6_7395_0_1, dd_Smed_v6_7395_0_1, [RH, Score=337, Expect=9e-114]} {RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1310_17432.1, RNA1509_27696, RNA1509_38773, RNA1509_53331} {RNA1509_27696, RNA1509_38773, RNA1509_53331, RNA815_6952}
15. MligTC455_43334 7286 151.78 Mlig455_054088

Neo: -

Age: logFC(26M/2M)=0.327

Region-enriched R3: 1.908/0.00014

CTSB 4.237 - 0.751 0.824 0.960 0.730 0.972 Mlig455_054088 {REF} {Length: 2579} {Pfam: Papain family cysteine protease [PF00112.25, score=227.1]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=387, Expect=1e-134]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=387, Expect=1e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=369, Expect=2e-127]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=338, Expect=1e-115]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=424, Expect=2e-149]} {RNA1509_448} {RNA1310_24539, RNA1509_448} {RNA1509_448, RNA815_4531}
16. MligTC455_39169 881 18.35 Mlig455_063890

Neo: -

Age: -

Region-enriched R3: 3.017/0.00000

ALDH2 4.205 0.721 0.852 - 0.961 0.828 0.843 Mlig455_063890 {REF} {Length: 2688} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=591.3]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=777, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_1186, RNA1509_20297} {RNA1310_3799.1, RNA1509_20297} {RNA1509_20297, RNA815_1286.1}
17. MligTC455_42150 1601 33.36 Mlig455_031740

Neo: -

Age: -

Region-enriched R3: 1.735/0.01830

4.104 0.706 0.829 0.732 - 0.957 0.880 Mlig455_031740 {REF} {Length: 2276} {Pfam: Lectin C-type domain [PF00059.23, score=29.1]} {Celegans: WBGene00016619, C43H6.6, [Score=48.9, Expect=5e-06]} {RNA1509_9329} {RNA1310_19331.2} {RNA815_8190.1}
18. MligTC455_53877 1399 29.15 Mlig455_016664

Neo: -

Age: logFC(26M/2M)=0.488

Region-enriched R3: 1.947/0.00083
Region-enriched R4: 1.666/0.01644

CLCA1 4.089 - 0.728 0.739 0.967 0.798 0.857 Mlig455_016664 {REF} {Length: 4164} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=169.0]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=4e-43]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=163, Expect=2e-42]} {RNA1509_1021} {RNA1310_5461.1} {RNA815_1665}
19. MligTC455_27338 4582 95.45 Mlig455_037635, Mlig455_069899

Neo: -

Age: -

Region-enriched R3: 2.047/0.00162

CLCA1, CLCA4 3.746 - 0.936 - 0.963 0.915 0.932

Mlig455_037635 {REF} {Length: 4031} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=201.4]; von Willebrand factor type A domain [PF00092.30, score=28.8]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=249, Expect=5e-69]} {Mouse: ENSMUSG00000074195, Clca4b, chloride channel accessory 4B, [Score=244, Expect=2e-67]; ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=243, Expect=7e-67]; ENSMUSG00000056025, Clca3a1, chloride channel accessory 3A1, [Score=241, Expect=2e-66]; ENSMUSG00000028262, Clca3a2, chloride channel accessory 3A2, [Score=240, Expect=4e-66]; ENSMUSG00000068547, Clca4a, chloride channel accessory 4A, [Score=237, Expect=5e-65]; ENSMUSG00000037033, Clca3b, chloride channel accessory 3B, [Score=234, Expect=1e-63]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=146, Expect=6e-36]} {RNA1509_1957} {RNA1310_1149.2} {RNA815_989.1}

Mlig455_069899 {REF} {Length: 3833} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=68.1]; von Willebrand factor type A domain [PF00092.30, score=56.9]; von Willebrand factor type A domain [PF13519.8, score=40.4]; von Willebrand factor type A domain [PF13768.8, score=26.5]; VWA domain containing CoxE-like protein [PF05762.16, score=23.6]} {Human: ENSG00000016602, CLCA4, chloride channel accessory 4, [Score=150, Expect=5e-37]} {Mouse: ENSMUSG00000028262, Clca3a2, chloride channel accessory 3A2, [Score=159, Expect=7e-40]; ENSMUSG00000056025, Clca3a1, chloride channel accessory 3A1, [Score=158, Expect=1e-39]; ENSMUSG00000037033, Clca3b, chloride channel accessory 3B, [Score=156, Expect=8e-39]; ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=152, Expect=2e-37]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [Score=105, Expect=2e-23]} {RNA1509_1957} {RNA1310_1149.2} {RNA815_989.1}
20. MligTC455_35666 3073 64.02 Mlig455_024866

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.297

Region-enriched R3: 1.613/0.00014

AC099489.1 3.664 - - 0.870 0.967 0.970 0.857 Mlig455_024866 {REF} {Length: 12799} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=87.8]; Domain of unknown function (DUF1943) [PF09172.13, score=66.5]; von Willebrand factor type D domain [PF00094.27, score=29.7]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=128, Expect=3e-28]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=67.8, Expect=3e-10]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=94.7, Expect=1e-18]} {RNA1509_27087} {RNA1310_1234.2} {RNA815_55}
21. MligTC455_53879 3408 71 Mlig455_056363

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.852/0.00001

CLCA1 3.662 - 0.886 - 0.979 0.869 0.928 Mlig455_056363 {REF} {Length: 3111} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=167.5]; von Willebrand factor type A domain [PF00092.30, score=46.2]; von Willebrand factor type A domain [PF13519.8, score=42.1]; von Willebrand factor type A domain [PF13768.8, score=37.2]; VWA domain containing CoxE-like protein [PF05762.16, score=23.6]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [RH, Score=265, Expect=9e-75]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [RH, Score=273, Expect=6e-78]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [RH, Score=178, Expect=5e-46]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
22. MligTC455_16658 1547 32.23 Mlig455_056718, Mlig455_060300

Neo: -

Age: -

Region-enriched R3: 1.971/0.00155
Region-enriched R4: 1.653/0.02745

3.64 0.798 - - 0.958 0.953 0.931

Mlig455_056718 {REF} {Length: 1714} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=44.7]} {RNA1509_50620, RNA1509_51103, RNA1509_8737} {RNA1310_8838, RNA1509_50620, RNA1509_51103} {RNA1509_50620, RNA1509_51103, RNA815_7244}

Mlig455_060300 {REF} {Length: 1815} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=46.9]} {Smed: dd_Smed_v6_855_0_1, dd_Smed_v6_855_0_1, [Score=47.0, Expect=5e-06]} {RNA1509_8737} {RNA1310_8838, RNA1509_8737} {RNA1509_8737, RNA815_7244}
23. MligTC455_20358 3816 79.5 Mlig455_051035

Neo: -

Age: logFC(26M/2M)=0.321

Region-enriched R3: 1.944/0.00005
Region-enriched R6: 1.584/0.00678

SLC15A1 3.597 - 0.873 - 0.965 0.954 0.805 Mlig455_051035 {REF} {Length: 1758} {Pfam: POT family [PF00854.23, score=33.7]} {Human: ENSG00000088386, SLC15A1, solute carrier family 15 member 1, [Score=85.1, Expect=5e-17]} {Mouse: ENSMUSG00000025557, Slc15a1, solute carrier family 15 (oligopeptide transporter), member 1, [Score=86.7, Expect=1e-17]} {Dmel: FBgn0028491, CG2930, [Score=99.0, Expect=8e-22]} {Celegans: WBGene00003878, pept-3, Peptide transporter 3, [Score=75.5, Expect=2e-14]} {Smed: dd_Smed_v6_4941_0_1, dd_Smed_v6_4941_0_1, [Score=91.7, Expect=1e-19]} {RNA1509_7670} {RNA1310_5104.2} {RNA815_1763.1}
24. MligTC455_39170 3221 67.1 Mlig455_038903

Neo: -

Age: logFC(26M/2M)=0.340

Region-enriched R3: 2.495/0.00000
Region-enriched R4: 1.609/0.00501
Region-enriched R5: 1.221/0.00810

ALDH2 3.589 - 0.894 - 0.902 0.964 0.829 Mlig455_038903 {REF} {Length: 2307} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=593.4]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=780, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=725, Expect=0.0]} {RNA1509_1186} {RNA1310_3799.1} {RNA815_1286.1}
25. MligTC455_18866 706 14.71 Mlig455_027285

Neo: -

Age: Down-Up-Down

3.585 - 0.866 - 0.984 0.854 0.881 Mlig455_027285 {REF} {Length: 736} {RNA1509_12836} {RNA1310_17576.2} {RNA815_6182.1}
26. MligTC455_19519 6580 137.09 Mlig455_046878

Neo: -

Age: -

GLUL 3.572 - - 0.873 0.955 0.858 0.886 Mlig455_046878 {REF} {Length: 1555} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=56.6]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=52.0]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=508, Expect=4e-179]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=509, Expect=0.0]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=525, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=510, Expect=0.0]} {Smed: dd_Smed_v6_646_0_1, dd_Smed_v6_646_0_1, [RH, Score=566, Expect=0.0]} {RNA1509_506} {RNA1310_19328} {RNA815_7220.1}
27. MligTC455_48071 1712 35.67 Mlig455_048082

Neo: -

Age: logFC(26M/2M)=-0.321

Region-enriched R4: 1.489/0.04451

HSD11B1 3.543 - 0.856 0.877 - 0.973 0.837 Mlig455_048082 {REF} {Length: 1293} {Pfam: short chain dehydrogenase [PF00106.27, score=123.3]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=75.2]; KR domain [PF08659.12, score=26.1]} {Human: ENSG00000117594, HSD11B1, hydroxysteroid 11-beta dehydrogenase 1, [Score=155, Expect=4e-45]} {Mouse: ENSMUSG00000016194, Hsd11b1, hydroxysteroid 11-beta dehydrogenase 1, [RH, Score=150, Expect=1e-43]} {Dmel: FBgn0027583, CG7601, [Score=82.4, Expect=9e-18]} {Celegans: WBGene00000982, dhs-19, DeHydrogenases, Short chain, [Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_4976_0_1, dd_Smed_v6_4976_0_1, [Score=62.8, Expect=3e-11]} {RNA1509_14549, RNA1509_28912} {RNA1310_26648, RNA1509_14549, RNA1509_28912} {RNA1509_14549, RNA1509_28912, RNA815_11342}
28. MligTC455_35632 6861 142.93 Mlig455_047206

Neo: -

Age: -

Region-enriched R3: 1.984/0.00032
Region-enriched R4: 1.605/0.01274
Region-enriched R5: 1.441/0.00908

DHDH 3.539 - - 0.758 0.951 0.925 0.905 Mlig455_047206 {REF} {Length: 1483} {Pfam: Oxidoreductase family, NAD-binding Rossmann fold [PF01408.24, score=86.6]; Oxidoreductase family, C-terminal alpha/beta domain [PF02894.19, score=32.8]} {Human: ENSG00000104808, DHDH, dihydrodiol dehydrogenase, [RH, Score=245, Expect=8e-79]} {Mouse: ENSMUSG00000011382, Dhdh, dihydrodiol dehydrogenase (dimeric), [RH, Score=247, Expect=1e-79]} {Dmel: FBgn0031418, CG3609, [Score=229, Expect=5e-73]} {Smed: dd_Smed_v6_7643_0_1, dd_Smed_v6_7643_0_1, [RH, Score=211, Expect=2e-66]} {RNA1509_4889} {RNA1310_24236} {RNA815_11111.1}
29. MligTC455_50034 2671 55.65 Mlig455_000005

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.540

Region-enriched R3: 1.249/0.00057

SPHK1 3.529 - - 0.786 0.985 0.908 0.850 Mlig455_000005 {REF} {Length: 2212} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=70.4]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=144, Expect=1e-37]} {Mouse: ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=140, Expect=1e-35]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=134, Expect=1e-33]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=121, Expect=3e-30]} {RNA1509_19326} {RNA1310_4471, RNA1509_19326} {RNA1509_19326, RNA815_1161}
30. MligTC455_31827 5047 105.14 Mlig455_047227, Mlig455_047295

Neo: -

Age: Up-Down-Up

Region-enriched R3: 1.850/0.00112
Region-enriched R4: 1.750/0.00523
Region-enriched R5: 1.376/0.01271

3.525 - - 0.779 0.974 0.844 0.928

Mlig455_047227 {REF} {Length: 2245} {Pfam: VDE lipocalin domain [PF07137.13, score=62.5]} {RNA1509_13014, RNA1509_14776} {RNA1310_14334.1, RNA1509_14776} {RNA1509_14776, RNA815_7820}

Mlig455_047295 {REF} {Length: 2123} {Pfam: VDE lipocalin domain [PF07137.13, score=57.7]} {RNA1509_13014} {RNA1310_14334.1, RNA1509_13014} {RNA1509_13014, RNA815_7820}
31. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 3.502 - 0.907 0.799 - 0.981 0.815

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
32. MligTC455_21829 5023 104.65 Mlig455_014094

Neo: -

Age: -

Region-enriched R4: 1.409/0.02548
Region-enriched R3: 1.341/0.03362

3.496 - 0.796 - 0.971 0.857 0.872 Mlig455_014094 {REF} {Length: 3099} {Pfam: Ependymin [PF00811.20, score=62.5]} {RNA1509_29432} {RNA1310_26645, RNA1509_29432} {RNA1509_29432, RNA815_4988.2}
33. MligTC455_35652 9154 190.71 Mlig455_057115

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.261

Region-enriched R3: 1.585/0.00213
Region-enriched R5: 1.102/0.03479

CD82 3.476 - - 0.895 0.734 0.890 0.957 Mlig455_057115 {REF} {Length: 1682} {Pfam: Tetraspanin family [PF00335.22, score=118.2]} {Human: ENSG00000085117, CD82, CD82 molecule, [Score=68.9, Expect=5e-13]} {Mouse: ENSMUSG00000030342, Cd9, CD9 antigen, [Score=73.2, Expect=7e-15]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [RH, Score=110, Expect=3e-28]} {Celegans: WBGene00006634, tsp-8, Tetraspanin, [Score=56.2, Expect=5e-09]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=97.1, Expect=1e-23]} {RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911} {RNA1310_22327, RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911} {RNA1509_13954, RNA1509_2691, RNA1509_27048, RNA1509_4769, RNA1509_58598, RNA1509_58951, RNA1509_9364, RNA1509_9911, RNA815_10761}
34. MligTC455_11650 1098 22.87 Mlig455_007133

Neo: -

Age: logFC(26M/2M)=1.455

Region-enriched R4: 2.055/0.00000
Region-enriched R3: 1.617/0.00001
Region-enriched R5: 1.032/0.00532

3.444 - - 0.707 0.979 0.922 0.836 Mlig455_007133 {REF} {Length: 1372} {Pfam: Tyrosine phosphatase family [PF13350.8, score=133.9]; Tyrosine phosphatase family [PF03162.15, score=32.8]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [RH, Score=96.3, Expect=2e-22]} {RNA1509_24412} {RNA1310_29199} {RNA815_14210.1}
35. MligTC455_43333 11678 243.29 Mlig455_036055

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.186

Region-enriched R3: 1.916/0.00004
Region-enriched R6: 1.435/0.01562
Region-enriched R5: 1.079/0.03201

CTSB 3.413 - - 0.742 0.963 0.732 0.976 Mlig455_036055 {REF} {Length: 1907} {Pfam: Papain family cysteine protease [PF00112.25, score=227.2]; Peptidase family C1 propeptide [PF08127.15, score=44.5]} {Human: ENSG00000164733, CTSB, cathepsin B, [RH, Score=388, Expect=7e-135]} {Mouse: ENSMUSG00000021939, Ctsb, cathepsin B, [RH, Score=385, Expect=5e-134]} {Dmel: FBgn0030521, CtsB1, Cathepsin B1, [RH, Score=366, Expect=1e-126]} {Celegans: WBGene00010204, F57F5.1, [RH, Score=336, Expect=1e-114]} {Smed: dd_Smed_v6_81_0_1, dd_Smed_v6_81_0_1, [RH, Score=427, Expect=2e-150]} {RNA1509_2988, RNA1509_448} {RNA1310_24539, RNA1509_2988} {RNA1509_2988, RNA815_4531}
36. MligTC455_33319 4306 89.7 Mlig455_027532

Neo: -

Age: logFC(26M/2M)=1.169

Region-enriched R3: 1.852/0.00003
Region-enriched R5: 1.035/0.02995

STS 3.402 - - 0.777 0.983 0.887 0.755 Mlig455_027532 {REF} {Length: 2207} {TRANSSPLICED} {Pfam: Sulfatase [PF00884.25, score=269.3]; C-terminal region of aryl-sulfatase [PF14707.8, score=89.8]; Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=34.8]} {Human: ENSG00000101846, STS, steroid sulfatase, [RH, Score=474, Expect=2e-161]} {Mouse: ENSMUSG00000022620, Arsa, arylsulfatase A, [Score=194, Expect=7e-55]} {Dmel: FBgn0036765, CG7408, [Score=124, Expect=7e-30]} {Celegans: WBGene00006309, sul-2, SULfatase domain protein, [Score=131, Expect=6e-33]} {RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410} {RNA1310_7885.2, RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410} {RNA1509_15815, RNA1509_18792, RNA1509_22490, RNA1509_49410, RNA815_3164.1}
37. MligTC455_40311 795 16.57 Mlig455_005646

Neo: -

Age: logFC(26M/2M)=-1.077

Region-enriched R4: 2.244/0.00079
Region-enriched R5: 1.789/0.00084

CYP2J2 3.364 - 0.713 - 0.983 0.864 0.804 Mlig455_005646 {REF} {Length: 2326} {Pfam: Cytochrome P450 [PF00067.24, score=345.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [RH, Score=303, Expect=4e-97]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=280, Expect=2e-88]; ENSMUSG00000042248, Cyp2c37, cytochrome P450, family 2. subfamily c, polypeptide 37, [RH, Score=280, Expect=1e-88]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [RH, Score=278, Expect=3e-87]; ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=276, Expect=8e-87]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=272, Expect=3e-85]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [RH, Score=271, Expect=1e-84]; ENSMUSG00000054827, Cyp2c50, cytochrome P450, family 2, subfamily c, polypeptide 50, [RH, Score=270, Expect=1e-84]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [RH, Score=270, Expect=2e-84]; ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [RH, Score=267, Expect=2e-83]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [RH, Score=266, Expect=6e-83]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=223, Expect=5e-66]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [RH, Score=249, Expect=1e-76]} {Smed: dd_Smed_v6_4449_0_1, dd_Smed_v6_4449_0_1, [Score=260, Expect=8e-81]} {RNA1509_32472} {RNA1310_10280} {RNA815_4805}
38. MligTC455_22592 6211 129.4 Mlig455_000657

Neo: -

Age: -

Region-enriched R4: 1.907/0.00463
Region-enriched R3: 1.880/0.00180
Region-enriched R5: 1.420/0.01682

FTH1 3.355 - 0.875 0.789 0.956 - 0.735 Mlig455_000657 {REF} {Length: 1242} {Pfam: Ferritin-like domain [PF00210.26, score=95.7]} {Human: ENSG00000167996, FTH1, ferritin heavy chain 1, [Score=109, Expect=8e-30]} {Mouse: ENSMUSG00000024661, Fth1, ferritin heavy polypeptide 1, [Score=103, Expect=7e-28]; ENSMUSG00000024510, Ftmt, ferritin mitochondrial, [Score=101, Expect=3e-26]} {Dmel: FBgn0030449, Fer3HCH, Ferritin 3 heavy chain homologue, [Score=97.8, Expect=2e-25]} {Celegans: WBGene00001501, ftn-2, Ferritin, [Score=118, Expect=1e-33]} {Smed: dd_Smed_v6_3974_0_1, dd_Smed_v6_3974_0_1, [Score=124, Expect=3e-36]} {RNA1509_8084} {RNA1310_36954.1} {RNA815_13698.3}
39. MligTC455_45292 3276 68.26 Mlig455_051579

Neo: -

Age: -

Region-enriched R3: 1.720/0.00958

SUSD2 3.332 - - 0.770 0.957 0.755 0.850 Mlig455_051579 {REF} {Length: 4293} {Pfam: AMOP domain [PF03782.19, score=54.3]; von Willebrand factor type D domain [PF00094.27, score=35.3]; Nidogen-like [PF06119.16, score=29.2]} {Human: ENSG00000099994, SUSD2, sushi domain containing 2, [Score=117, Expect=5e-26]} {Mouse: ENSMUSG00000006342, Susd2, sushi domain containing 2, [RH, Score=136, Expect=2e-32]} {Dmel: FBgn0051004, mesh, [Score=159, Expect=6e-39]} {RNA1509_1220, RNA1509_17521, RNA1509_46499} {RNA1310_2718.1, RNA1509_17521, RNA1509_46499} {RNA1509_17521, RNA1509_46499, RNA815_500}
40. MligTC455_45981 1146 23.87 Mlig455_050420

Neo: -

Age: logFC(26M/2M)=0.478

CYP2J2 3.268 - 0.706 - 0.969 0.810 0.783 Mlig455_050420 {REF} {Length: 2403} {Pfam: Cytochrome P450 [PF00067.24, score=310.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=234, Expect=2e-70]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=231, Expect=8e-69]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=237, Expect=6e-72]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=236, Expect=1e-71]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=234, Expect=9e-71]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=233, Expect=4e-70]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=231, Expect=2e-69]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=231, Expect=2e-69]; ENSMUSG00000030670, Cyp2r1, cytochrome P450, family 2, subfamily r, polypeptide 1, [Score=226, Expect=1e-67]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=228, Expect=3e-68]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=228, Expect=1e-68]} {Smed: dd_Smed_v6_3919_0_3, dd_Smed_v6_3919_0_3, [Score=264, Expect=2e-82]} {RNA1509_22870} {RNA1310_10897, RNA1509_22870} {RNA1509_22870, RNA815_4157.1}
41. MligTC455_39549 1949 40.61 Mlig455_004602

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.654

Region-enriched R5: 2.577/0.00276
Region-enriched R4: 2.372/0.03782

3.235 - 0.758 - 0.968 0.767 0.742 Mlig455_004602 {REF} {Length: 3069} {Pfam: Universal stress protein family [PF00582.28, score=98.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=106, Expect=1e-29]} {RNA1509_6489} {RNA1310_12949, RNA1509_6489} {RNA1509_6489, RNA815_11224}
42. MligTC455_20464 3164 65.93 Mlig455_036496, Mlig455_056384

Neo: -

Age: -

Region-enriched R3: 1.967/0.00269
Region-enriched R4: 1.871/0.00861

RAB35 3.164 - - 0.780 0.731 0.703 0.950

Mlig455_036496 {REF} {Length: 1520} {Pfam: Ras family [PF00071.24, score=127.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=49.9]; RsgA GTPase [PF03193.18, score=37.9]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.9]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.1]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=5e-28]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=8e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=8e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=146, Expect=4e-44]} {RNA1509_21258} {RNA1310_21310.1} {RNA815_8782.1}

Mlig455_056384 {REF} {Length: 1510} {Pfam: Ras family [PF00071.24, score=127.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=89.3]; ADP-ribosylation factor family [PF00025.23, score=51.7]; RsgA GTPase [PF03193.18, score=37.8]; 50S ribosome-binding GTPase [PF01926.25, score=24.4]; Signal recognition particle receptor beta subunit [PF09439.12, score=21.0]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.6]} {Human: ENSG00000111737, RAB35, RAB35, member RAS oncogene family, [Score=110, Expect=2e-29]; ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=105, Expect=9e-28]} {Mouse: ENSMUSG00000029518, Rab35, RAB35, member RAS oncogene family, [Score=110, Expect=1e-29]; ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=106, Expect=4e-28]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=105, Expect=2e-27]} {Dmel: FBgn0031090, Rab35, [Score=118, Expect=6e-33]} {Celegans: WBGene00004277, rab-18, Ras-related protein Rab-18, [Score=125, Expect=7e-36]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [RH, Score=147, Expect=4e-44]} {RNA1509_12602, RNA1509_21258} {RNA1310_21310.1, RNA1509_12602, RNA1509_21258} {RNA1509_12602, RNA1509_21258, RNA815_8782.1}
43. MligTC455_43368 6858 142.86 Mlig455_048986, Mlig455_049002

Neo: -

Age: Up-Down-Down

ACHE 2.728 - 0.954 - 0.913 - 0.861

Mlig455_048986 {REF} {Length: 14781} {Pfam: Carboxylesterase family [PF00135.30, score=2484.2]; alpha/beta hydrolase fold [PF07859.15, score=129.3]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=8e-66]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=209, Expect=1e-56]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=189, Expect=3e-49]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=213, Expect=1e-57]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=202, Expect=8e-54]} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_82, RNA1509_8879} {RNA1310_83.1, RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879} {RNA1509_1156, RNA1509_14744, RNA1509_15426, RNA1509_18645, RNA1509_25748, RNA1509_38830, RNA1509_6237, RNA1509_8879, RNA815_40.1}

Mlig455_049002 {REF} {Length: 15214} {Pfam: Carboxylesterase family [PF00135.30, score=2695.8]; alpha/beta hydrolase fold [PF07859.15, score=131.9]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=238, Expect=1e-65]} {Mouse: ENSMUSG00000058019, Ces5a, carboxylesterase 5A, [RH, Score=211, Expect=7e-57]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=191, Expect=5e-50]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=207, Expect=1e-55]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=199, Expect=5e-53]} {RNA1509_82, RNA1509_8738} {RNA1310_83.1, RNA1509_8738} {RNA1509_8738, RNA815_40.1}
44. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

2.695 - 0.860 - - 0.971 0.864

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
45. MligTC455_48360 594 12.37 Mlig455_034363

Neo: -

Age: -

Region-enriched R3: 2.361/0.00279
Region-enriched R4: 2.128/0.02443

2.687 - 0.888 - - 0.959 0.840 Mlig455_034363 {REF} {Length: 3889} {Pfam: Death domain [PF00531.24, score=30.1]} {Celegans: WBGene00002041, hum-8, Heavy chain, Unconventional Myosin, [Score=50.4, Expect=6e-06]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [Score=105, Expect=3e-23]} {RNA1509_29690, RNA1509_59375} {RNA1310_5206.1, RNA1509_59375} {RNA1509_59375, RNA815_3494}
46. MligTC455_21474 27672 576.49 Mlig455_064180

Neo: -

Age: -

Region-enriched R3: 1.810/0.00061

CTSV 2.662 - - 0.870 0.967 - 0.825 Mlig455_064180 {REF} {Length: 1968} {Pfam: Papain family cysteine protease [PF00112.25, score=291.7]; Cathepsin propeptide inhibitor domain (I29) [PF08246.14, score=54.9]; Peptidase C1-like family [PF03051.17, score=27.5]} {Human: ENSG00000136943, CTSV, cathepsin V, [RH, Score=358, Expect=3e-123]; ENSG00000135047, CTSL, cathepsin L, [RH, Score=356, Expect=2e-122]} {Mouse: ENSMUSG00000021477, Ctsl, cathepsin L, [RH, Score=348, Expect=9e-120]; ENSMUSG00000042243, BC051665, cDNA sequence BC051665, [RH, Score=335, Expect=1e-114]; ENSMUSG00000056728, Ctsll3, cathepsin L-like 3, [RH, Score=333, Expect=2e-113]} {Dmel: FBgn0013770, Cp1, Cysteine proteinase-1, [Score=359, Expect=6e-124]} {Celegans: WBGene00000776, cpl-1, CathePsin L family, [RH, Score=336, Expect=6e-115]} {Smed: dd_Smed_v6_48_0_1, dd_Smed_v6_48_0_1, [RH, Score=428, Expect=2e-151]} {RNA1509_124} {RNA1310_16613} {RNA815_7527}
47. MligTC455_26632 2223 46.31 Mlig455_010979

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.932

Region-enriched R3: 1.352/0.01651

ASGR2 2.658 - - - 0.975 0.736 0.947 Mlig455_010979 {REF} {Length: 3718} {Pfam: Lectin C-type domain [PF00059.23, score=51.8]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=29.4]} {Human: ENSG00000161944, ASGR2, asialoglycoprotein receptor 2, [Score=53.1, Expect=6e-07]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=62.0, Expect=2e-09]; ENSMUSG00000020695, Mrc2, mannose receptor, C type 2, [Score=60.5, Expect=6e-09]} {Dmel: FBgn0029697, CG15570, [Score=82.4, Expect=7e-16]} {Celegans: WBGene00020585, clec-178, C-type LECtin, [Score=57.4, Expect=2e-09]} {Smed: dd_Smed_v6_1489_0_1, dd_Smed_v6_1489_0_1, [Score=48.5, Expect=7e-06]} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1310_25013.1, RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412} {RNA1509_10049, RNA1509_1147, RNA1509_39537, RNA1509_48412, RNA815_11727}
48. MligTC455_30094 4128 86.01 Mlig455_015674, Mlig455_062483

Neo: -

Age: Down-Down-Up

2.641 - - - 0.895 0.953 0.793

Mlig455_015674 {REF} {Length: 3057} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=126.7]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [Score=421, Expect=4e-138]} {RNA1509_3901} {RNA1310_1179.2} {RNA815_296.2}

Mlig455_062483 {REF} {Length: 3106} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=125.5]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [RH, Score=486, Expect=1e-161]} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1310_1179.1, RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971, RNA815_296.2}
49. MligTC455_34855 1221 25.44 Mlig455_062463

Neo: -

Age: logFC(26M/2M)=0.211

Region-enriched R4: 1.791/0.02708
Region-enriched R3: 1.675/0.02300

CYP2J2 2.627 - 0.960 - - 0.852 0.815 Mlig455_062463 {REF} {Length: 3167} {Pfam: Cytochrome P450 [PF00067.24, score=328.5]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=271, Expect=7e-85]} {Mouse: ENSMUSG00000028571, Cyp2j13, cytochrome P450, family 2, subfamily j, polypeptide 13, [RH, Score=275, Expect=4e-86]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [RH, Score=266, Expect=5e-83]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [RH, Score=263, Expect=1e-81]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=237, Expect=1e-71]} {Celegans: WBGene00018413, cyp-33C4, CYtochrome P450 family, [RH, Score=267, Expect=1e-83]} {Smed: dd_Smed_v6_2351_0_2, dd_Smed_v6_2351_0_2, [Score=269, Expect=2e-84]} {RNA1509_51219} {RNA1310_15059, RNA1509_51219} {RNA1509_51219, RNA815_5935.1}
50. MligTC455_18979 4242 88.37 Mlig455_051061

Neo: -

Age: -

TSPAN6 2.623 - - 0.818 0.961 - 0.844 Mlig455_051061 {REF} {Length: 2196} {Pfam: Tetraspanin family [PF00335.22, score=103.6]} {Human: ENSG00000000003, TSPAN6, tetraspanin 6, [Score=67.4, Expect=1e-12]} {Mouse: ENSMUSG00000028699, Tspan1, tetraspanin 1, [Score=68.9, Expect=2e-13]} {Dmel: FBgn0033130, Tsp42Ei, Tetraspanin 42Ei, [Score=60.5, Expect=2e-10]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [Score=69.7, Expect=1e-13]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [Score=93.2, Expect=5e-22]} {RNA1509_4295} {RNA1310_961, RNA1509_4295} {RNA1509_4295, RNA815_10076}
51. MligTC455_40620 3703 77.15 Mlig455_034547, Mlig455_064817

Neo: -

Age: logFC(26M/2M)=0.348

Region-enriched R3: 1.638/0.00022

SGPL1 2.619 - - - 0.749 0.903 0.967

Mlig455_034547 {REF} {Length: 1975} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=71.4]; Aminotransferase class-V [PF00266.21, score=28.0]} {Human: ENSG00000166224, SGPL1, sphingosine-1-phosphate lyase 1, [Score=313, Expect=1e-99]} {Mouse: ENSMUSG00000020097, Sgpl1, sphingosine phosphate lyase 1, [Score=313, Expect=8e-100]} {Dmel: FBgn0010591, Sply, Sphingosine-1-phosphate lyase, [Score=286, Expect=9e-90]} {Celegans: WBGene00004981, spl-1, Sphingosine-1-phosphate lyase, [Score=283, Expect=2e-88]} {Smed: dd_Smed_v6_4459_0_1, dd_Smed_v6_4459_0_1, [Score=301, Expect=2e-95]} {RNA1509_16302} {RNA1310_14912} {RNA815_7513}

Mlig455_064817 {REF} {Length: 3062} {Pfam: Pyridoxal-dependent decarboxylase conserved domain [PF00282.21, score=73.9]; Aminotransferase class-V [PF00266.21, score=28.0]} {Human: ENSG00000166224, SGPL1, sphingosine-1-phosphate lyase 1, [Score=316, Expect=1e-100]} {Mouse: ENSMUSG00000020097, Sgpl1, sphingosine phosphate lyase 1, [Score=315, Expect=2e-100]} {Dmel: FBgn0010591, Sply, Sphingosine-1-phosphate lyase, [Score=283, Expect=1e-88]} {Celegans: WBGene00004981, spl-1, Sphingosine-1-phosphate lyase, [Score=286, Expect=1e-89]} {Smed: dd_Smed_v6_4459_0_1, dd_Smed_v6_4459_0_1, [Score=301, Expect=1e-95]} {RNA1509_12635, RNA1509_16302} {RNA1310_14912, RNA1509_12635, RNA1509_16302} {RNA1509_12635, RNA1509_16302, RNA815_7513}
52. MligTC455_31506 586 12.2 Mlig455_059744

Neo: -

Age: -

Region-enriched R4: 2.875/0.00022
Region-enriched R3: 2.468/0.00160
Region-enriched R5: 2.189/0.00308

DDO 2.607 - - - 0.968 0.905 0.734 Mlig455_059744 {REF} {Length: 2018} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=129.1]} {Human: ENSG00000203797, DDO, D-aspartate oxidase, [RH, Score=218, Expect=1e-67]; ENSG00000110887, DAO, D-amino acid oxidase, [RH, Score=209, Expect=1e-64]} {Mouse: ENSMUSG00000042096, Dao, D-amino acid oxidase, [RH, Score=216, Expect=3e-67]; ENSMUSG00000063428, Ddo, D-aspartate oxidase, [RH, Score=216, Expect=1e-67]} {Dmel: FBgn0031860, CG11236, [RH, Score=211, Expect=6e-66]} {Celegans: WBGene00022076, daao-1, D-amino-acid oxidase, [Score=174, Expect=1e-51]} {Smed: dd_Smed_v6_3560_0_1, dd_Smed_v6_3560_0_1, [RH, Score=246, Expect=2e-79]} {RNA1509_1569} {RNA1310_11182} {RNA815_6961}
53. MligTC455_40294 928 19.33 Mlig455_062769

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.415

Region-enriched R4: 2.693/0.00000
Region-enriched R3: 1.531/0.00694
Region-enriched R5: 1.366/0.00671

VAV1 2.578 - 0.798 - - 0.955 0.825 Mlig455_062769 {REF} {Length: 4319} {Pfam: SH2 domain [PF00017.26, score=34.9]; RhoGEF domain [PF00621.22, score=28.2]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=27.1]} {Human: ENSG00000141968, VAV1, vav guanine nucleotide exchange factor 1, [Score=93.6, Expect=5e-19]} {Mouse: ENSMUSG00000034116, Vav1, vav 1 oncogene, [Score=91.3, Expect=1e-18]} {Dmel: FBgn0040068, Vav, Vav guanine nucleotide exchange factor, [Score=61.2, Expect=2e-09]} {Celegans: WBGene00006887, vav-1, [Score=64.3, Expect=2e-10]} {RNA1509_11835} {RNA1310_8757} {RNA815_2576}
54. MligTC455_18365 1079 22.48 Mlig455_026312

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.583

IFI30 2.576 - 0.722 - 0.964 - 0.890 Mlig455_026312 {REF} {Length: 1095} {Pfam: Gamma interferon inducible lysosomal thiol reductase (GILT) [PF03227.18, score=101.0]} {Human: ENSG00000216490, IFI30, IFI30, lysosomal thiol reductase, [RH, Score=146, Expect=6e-43]} {Mouse: ENSMUSG00000110777, Ifi30, interferon gamma inducible protein 30, [RH, Score=121, Expect=3e-33]} {Dmel: FBgn0085638, CG41378, [Score=92.4, Expect=7e-23]} {Celegans: WBGene00009514, F37H8.5, GILT-like protein F37H8.5, [Score=100, Expect=2e-25]} {Smed: dd_Smed_v6_2024_0_1, dd_Smed_v6_2024_0_1, [Score=107, Expect=6e-29]} {RNA1509_13998, RNA1509_51694} {RNA1310_32351.1, RNA1509_13998, RNA1509_51694} {RNA1509_13998, RNA1509_51694, RNA815_17592}
55. MligTC455_49294 2730 56.88 Mlig455_030635

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.451

Region-enriched R3: 1.379/0.00585

SERPINB1 2.547 - - - 0.961 0.880 0.706 Mlig455_030635 {REF} {Length: 2337} {TRANSSPLICED} {Pfam: Serpin (serine protease inhibitor) [PF00079.22, score=369.3]} {Human: ENSG00000021355, SERPINB1, serpin family B member 1, [RH, Score=247, Expect=2e-78]; ENSG00000206072, SERPINB11, serpin family B member 11 (gene/pseudogene), [RH, Score=237, Expect=2e-74]} {Mouse: ENSMUSG00000052180, Serpinb6c, serine (or cysteine) peptidase inhibitor, clade B, member 6c, [RH, Score=255, Expect=1e-81]; ENSMUSG00000044734, Serpinb1a, serine (or cysteine) peptidase inhibitor, clade B, member 1a, [RH, Score=254, Expect=2e-81]; ENSMUSG00000047889, Serpinb6d, serine (or cysteine) peptidase inhibitor, clade B, member 6d, [RH, Score=246, Expect=4e-78]} {Dmel: FBgn0028983, Spn55B, Serpin 55B, [RH, Score=197, Expect=3e-59]} {Celegans: WBGene00005648, srp-7, SeRPin; Serine or cysteine protease inhibitor, [RH, Score=187, Expect=1e-55]} {Smed: dd_Smed_v6_3824_0_1, dd_Smed_v6_3824_0_1, [RH, Score=240, Expect=3e-76]} {RNA1509_12753, RNA1509_14486, RNA1509_1486, RNA1509_8328} {RNA1310_18852, RNA1509_12753, RNA1509_14486, RNA1509_1486, RNA1509_8328} {RNA1509_12753, RNA1509_14486, RNA1509_1486, RNA1509_8328, RNA815_2173}
56. MligTC455_43442 1075 22.4 Mlig455_064470

Neo: -

Age: -

Region-enriched R3: 1.454/0.00218
Region-enriched R4: 1.358/0.00888

RAB6B 2.519 - - 0.823 - 0.741 0.955 Mlig455_064470 {REF} {Length: 1223} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=49.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=44.7]; 50S ribosome-binding GTPase [PF01926.25, score=25.5]; Ferrous iron transport protein B [PF02421.20, score=21.6]; RsgA GTPase [PF03193.18, score=21.4]} {Human: ENSG00000154917, RAB6B, RAB6B, member RAS oncogene family, [Score=61.6, Expect=3e-11]; ENSG00000139998, RAB15, RAB15, member RAS oncogene family, [Score=61.2, Expect=5e-11]; ENSG00000175582, RAB6A, RAB6A, member RAS oncogene family, [Score=60.8, Expect=6e-11]; ENSG00000172794, RAB37, RAB37, member RAS oncogene family, [Score=60.5, Expect=8e-11]} {Mouse: ENSMUSG00000032549, Rab6b, RAB6B, member RAS oncogene family, [Score=61.6, Expect=2e-11]; ENSMUSG00000021062, Rab15, RAB15, member RAS oncogene family, [Score=61.2, Expect=3e-11]; ENSMUSG00000020732, Rab37, RAB37, member RAS oncogene family, [Score=61.2, Expect=3e-11]; ENSMUSG00000030704, Rab6a, RAB6A, member RAS oncogene family, [Score=60.8, Expect=4e-11]} {Dmel: FBgn0035155, RabX6, [Score=67.0, Expect=2e-13]} {Celegans: WBGene00004285, rab-37, RAB family, [Score=58.5, Expect=1e-10]} {Smed: dd_Smed_v6_2603_0_1, dd_Smed_v6_2603_0_1, [Score=68.6, Expect=2e-14]} {RNA1509_24794} {RNA1310_29753, RNA1509_24794} {RNA1509_24794, RNA815_15970}
57. MligTC455_44762 1411 29.4 Mlig455_054505, Mlig455_055363

Neo: -

Age: -

Region-enriched R4: 1.455/0.00954
Region-enriched R3: 1.386/0.00533
Region-enriched R5: 1.323/0.00126

TMEM144 2.51 - - - 0.970 0.731 0.809

Mlig455_054505 {REF} {Length: 1727} {Pfam: Transmembrane family, TMEM144 of transporters [PF07857.14, score=343.3]; Sugar transport protein [PF06800.14, score=32.7]} {Human: ENSG00000164124, TMEM144, transmembrane protein 144, [RH, Score=263, Expect=1e-84]} {Mouse: ENSMUSG00000027956, Tmem144, transmembrane protein 144, [RH, Score=274, Expect=3e-89]} {Celegans: WBGene00020096, R144.6, Transmembrane protein 144 homolog, [RH, Score=249, Expect=7e-80]} {Smed: dd_Smed_v6_4971_0_1, dd_Smed_v6_4971_0_1, [RH, Score=223, Expect=3e-69]} {RNA1509_20314} {RNA1310_19532, RNA1509_20314} {RNA1509_20314, RNA815_8427}

Mlig455_055363 {REF} {Length: 1660} {Pfam: Transmembrane family, TMEM144 of transporters [PF07857.14, score=343.3]; Sugar transport protein [PF06800.14, score=32.7]} {Human: ENSG00000164124, TMEM144, transmembrane protein 144, [RH, Score=263, Expect=1e-84]} {Mouse: ENSMUSG00000027956, Tmem144, transmembrane protein 144, [RH, Score=274, Expect=3e-89]} {Celegans: WBGene00020096, R144.6, Transmembrane protein 144 homolog, [RH, Score=249, Expect=7e-80]} {Smed: dd_Smed_v6_4971_0_1, dd_Smed_v6_4971_0_1, [RH, Score=223, Expect=3e-69]} {RNA1509_20314, RNA1509_24963, RNA1509_31718} {RNA1310_19532, RNA1509_24963, RNA1509_31718} {RNA1509_24963, RNA1509_31718, RNA815_8427}
58. MligTC455_44763 706 14.71 Mlig455_055422

Neo: -

Age: -

Region-enriched R4: 1.754/0.00115
Region-enriched R5: 1.353/0.00093
Region-enriched R3: 1.299/0.01581

TMEM144 2.508 - - - 0.971 0.726 0.811 Mlig455_055422 {REF} {Length: 1371} {Pfam: Transmembrane family, TMEM144 of transporters [PF07857.14, score=121.8]} {Human: ENSG00000164124, TMEM144, transmembrane protein 144, [Score=89.7, Expect=2e-19]} {Mouse: ENSMUSG00000027956, Tmem144, transmembrane protein 144, [Score=97.4, Expect=2e-22]} {Celegans: WBGene00020096, R144.6, Transmembrane protein 144 homolog, [Score=102, Expect=2e-24]} {Smed: dd_Smed_v6_4971_0_1, dd_Smed_v6_4971_0_1, [Score=102, Expect=1e-24]} {RNA1509_20314} {RNA1310_19532} {RNA815_8427}
59. MligTC455_51325 3851 80.23 Mlig455_021992, Mlig455_022042

Neo: -

Age: Down-Down-Up

DAB1 2.5 - 0.704 - 0.952 - 0.844

Mlig455_021992 {REF} {Length: 6250} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=59.6]} {RNA1509_30639} {RNA1310_12089} {RNA815_6330}

Mlig455_022042 {REF} {Length: 2259} {Human: ENSG00000173406, DAB1, DAB1, reelin adaptor protein, [RH, Score=70.9, Expect=2e-12]} {Mouse: ENSMUSG00000028519, Dab1, disabled 1, [RH, Score=70.5, Expect=1e-12]} {Dmel: FBgn0000414, Dab, Disabled, [RH, Score=70.5, Expect=1e-12]} {RNA1509_20226, RNA1509_30639, RNA1509_9008} {RNA1310_12089, RNA1509_20226, RNA1509_30639, RNA1509_9008} {RNA1509_20226, RNA1509_30639, RNA1509_9008, RNA815_6330}
60. MligTC455_19590 915 19.06 Mlig455_051962

Neo: -

Age: -

1.794 - - - 0.978 - 0.816 Mlig455_051962 {REF} {Length: 852} {RNA1509_20360} {RNA1310_37068, RNA1509_20360} {RNA1509_20360, RNA815_23648}
61. MligTC455_24698 664 13.84 Mlig455_002176

Neo: -

Age: Up-Down-Up

Region-enriched R3: 2.133/0.00000
Region-enriched R4: 1.095/0.04769

1.768 - - - - 0.972 0.796 Mlig455_002176 {REF} {Length: 1826} {TRANSSPLICED} {RNA1509_10156} {RNA1310_5607} {RNA815_1167}
62. MligTC455_39600 674 14.05 Mlig455_012926, Mlig455_031140, Mlig455_032440

Neo: -

Age: -

Region-enriched R3: 3.870/0.00079

1.764 - 0.810 - - 0.954 -

Mlig455_012926 {REF} {Length: 87} {NoTransDecoderORF} {RNA1509_3980} {RNA1310_20780.1} {RNA815_13375.1}

Mlig455_031140 {REF} {Length: 785} {NoTransDecoderORF} {RNA1509_20101} {RNA1310_14959.1} {RNA815_9852.1}

Mlig455_032440 {REF} {Length: 138} {NoTransDecoderORF} {RNA1509_3980} {RNA1310_20780.1} {RNA815_4111.1}
63. MligTC455_16022 616 12.83 Mlig455_048556

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.801/0.00244
Region-enriched R3: 1.214/0.03772

SLC10A3 1.752 - 0.801 - - 0.951 - Mlig455_048556 {REF} {Length: 1530} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=56.7]} {Human: ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [Score=95.5, Expect=6e-21]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [Score=92.0, Expect=5e-20]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=98.2, Expect=2e-22]} {Dmel: FBgn0030638, CG11655, [Score=141, Expect=2e-37]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=161, Expect=2e-44]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [Score=161, Expect=5e-45]} {RNA1509_13359} {RNA1310_13071} {RNA815_4905}
64. MligTC455_16023 622 12.96 Mlig455_048417, Mlig455_049055

Neo: -

Age: logFC(26M/2M)=-0.353

Region-enriched R4: 1.900/0.00082
Region-enriched R3: 1.176/0.03983

SLC10A3, SLC10A6 1.746 - 0.796 - - 0.950 -

Mlig455_048417 {REF} {Length: 2016} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=43.0]} {Human: ENSG00000145283, SLC10A6, solute carrier family 10 member 6, [Score=60.8, Expect=1e-09]; ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [Score=60.5, Expect=2e-09]} {Mouse: ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=59.7, Expect=2e-09]} {Dmel: FBgn0030638, CG11655, [Score=79.3, Expect=7e-16]} {Celegans: WBGene00044650, Y71G10AR.4, [Score=92.8, Expect=2e-20]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [Score=89.4, Expect=2e-19]} {RNA1509_13359} {RNA1310_13071} {RNA815_4905}

Mlig455_049055 {REF} {Length: 2118} {Pfam: Sodium Bile acid symporter family [PF01758.18, score=94.9]} {Human: ENSG00000126903, SLC10A3, solute carrier family 10 member 3, [RH, Score=130, Expect=3e-32]; ENSG00000100652, SLC10A1, solute carrier family 10 member 1, [RH, Score=125, Expect=4e-31]} {Mouse: ENSMUSG00000023073, Slc10a2, solute carrier family 10, member 2, [Score=127, Expect=3e-32]; ENSMUSG00000032806, Slc10a3, solute carrier family 10 (sodium/bile acid cotransporter family), member 3, [Score=124, Expect=2e-30]} {Dmel: FBgn0030638, CG11655, [RH, Score=191, Expect=2e-54]} {Celegans: WBGene00044650, Y71G10AR.4, [RH, Score=221, Expect=4e-65]} {Smed: dd_Smed_v6_10199_0_1, dd_Smed_v6_10199_0_1, [Score=229, Expect=4e-69]} {RNA1509_13359, RNA1509_35282} {RNA1310_13071, RNA1509_13359, RNA1509_35282} {RNA1509_13359, RNA1509_35282, RNA815_4905}
65. MligTC455_32319 1579 32.9 Mlig455_065963

Neo: -

Age: -

Region-enriched R4: 1.893/0.00270

CTSA 1.743 - - - - 0.959 0.784 Mlig455_065963 {REF} {Length: 1899} {TRANSSPLICED} {Pfam: Serine carboxypeptidase [PF00450.24, score=405.7]} {Human: ENSG00000064601, CTSA, cathepsin A, [RH, Score=417, Expect=1e-141]} {Mouse: ENSMUSG00000017760, Ctsa, cathepsin A, [RH, Score=425, Expect=1e-144]} {Dmel: FBgn0038738, CG4572, [Score=108, Expect=4e-25]} {Celegans: WBGene00019605, ctsa-1, Uncharacterized serine carboxypeptidase ctsa-1, [RH, Score=339, Expect=1e-111]} {Smed: dd_Smed_v6_785_0_1, dd_Smed_v6_785_0_1, [RH, Score=392, Expect=3e-132]} {RNA1509_366, RNA1509_39936} {RNA1310_10272.1, RNA1509_39936} {RNA1509_39936, RNA815_3612.1}
66. MligTC455_53235 770 16.04 Mlig455_068185

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.817

Region-enriched R4: 7.793/0.00001

1.689 - - - 0.973 - 0.716 Mlig455_068185 {REF} {Length: 736} {Pfam: Destabilase [PF05497.14, score=97.6]} {Dmel: FBgn0034162, CG6426, [RH, Score=52.8, Expect=4e-09]} {Celegans: WBGene00016670, ilys-3, Invertebrate-type lysozyme 3, [RH, Score=95.9, Expect=4e-26]} {RNA1509_44907} {RNA1310_54526.2} {RNA815_20968}
67. MligTC455_24881 55 1.14 Mlig455_001402

Neo: -

Age: Up-Down-Up

TBX1 0.985 - - - - 0.985 - Mlig455_001402 {REF} {Length: 3217} {TRANSSPLICED} {Pfam: T-box [PF00907.24, score=236.6]} {Human: ENSG00000184058, TBX1, T-box 1, [RH, Score=290, Expect=6e-90]} {Mouse: ENSMUSG00000009097, Tbx1, T-box 1, [RH, Score=290, Expect=1e-88]; ENSMUSG00000037477, Tbx10, T-box 10, [RH, Score=280, Expect=9e-86]} {Dmel: FBgn0021767, org-1, optomotor-blind-related-gene-1, [Score=268, Expect=5e-78]} {Celegans: WBGene00003376, mls-1, T-box transcription factor mls-1, [RH, Score=225, Expect=2e-67]} {Smed: dd_Smed_v6_26182_0_1, dd_Smed_v6_26182_0_1, [RH, Score=251, Expect=2e-76]} {RNA1509_58181} {RNA1310_40858} {RNA815_34334}
68. MligTC455_43948 3488 72.67 Mlig455_002834, Mlig455_002839

Neo: -

Age: logFC(26M/2M)=-0.402

Region-enriched R5: 1.557/0.01497

SLC32A1 0.975 - - - 0.975 - -

Mlig455_002834 {REF} {Length: 2083} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=180.6]} {Human: ENSG00000101438, SLC32A1, solute carrier family 32 member 1, [Score=183, Expect=6e-51]} {Mouse: ENSMUSG00000037771, Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, [Score=182, Expect=7e-51]} {Dmel: FBgn0033911, VGAT, Vesicular GABA Transporter, [Score=178, Expect=4e-49]} {Celegans: WBGene00006783, unc-47, Vesicular GABA transporter, [Score=189, Expect=6e-54]} {Smed: dd_Smed_v6_20353_0_1, dd_Smed_v6_20353_0_1, [RH, Score=382, Expect=2e-128]} {RNA1509_6347} {RNA1310_11411, RNA1509_6347} {RNA1509_6347, RNA815_4946}

Mlig455_002839 {REF} {Length: 1987} {Pfam: Transmembrane amino acid transporter protein [PF01490.20, score=180.6]} {Human: ENSG00000101438, SLC32A1, solute carrier family 32 member 1, [Score=183, Expect=6e-51]} {Mouse: ENSMUSG00000037771, Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, [Score=182, Expect=7e-51]} {Dmel: FBgn0033911, VGAT, Vesicular GABA Transporter, [Score=178, Expect=4e-49]} {Celegans: WBGene00006783, unc-47, Vesicular GABA transporter, [Score=189, Expect=6e-54]} {Smed: dd_Smed_v6_20353_0_1, dd_Smed_v6_20353_0_1, [RH, Score=382, Expect=2e-128]} {RNA1509_24687, RNA1509_28188, RNA1509_6347} {RNA1310_11411, RNA1509_24687, RNA1509_28188} {RNA1509_24687, RNA1509_28188, RNA815_4946}
69. MligTC455_50645 44 0.91 Mlig455_036533

Neo: -

Age: -

SCYL1 0.974 - - - - 0.974 - Mlig455_036533 {REF} {Length: 4260} {TRANSSPLICED} {Pfam: HEAT repeat [PF02985.24, score=41.4]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=37.1]; HEAT repeats [PF13646.8, score=32.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=25.7]; Protein kinase domain [PF00069.27, score=23.0]} {Human: ENSG00000142186, SCYL1, SCY1 like pseudokinase 1, [RH, Score=447, Expect=7e-145]} {Mouse: ENSMUSG00000024941, Scyl1, SCY1-like 1 (S. cerevisiae), [RH, Score=441, Expect=6e-143]} {Dmel: FBgn0260990, yata, [RH, Score=516, Expect=4e-171]} {Celegans: WBGene00012337, W07G4.3, [RH, Score=404, Expect=6e-129]} {Smed: dd_Smed_v6_3470_0_1, dd_Smed_v6_3470_0_1, [RH, Score=460, Expect=5e-152]} {RNA1509_21531, RNA1509_23084, RNA1509_58473} {RNA1310_4140, RNA1509_21531, RNA1509_23084, RNA1509_58473} {RNA1509_21531, RNA1509_23084, RNA1509_58473, RNA815_4060}
70. MligTC455_41793 128 2.66 Mlig455_056389

Neo: -

Age: logFC(26M/2M)=-0.406

CCDC96 0.966 - - - - 0.966 - Mlig455_056389 {REF} {Length: 2189} {Pfam: Domain of unknown function (DUF4201) [PF13870.8, score=154.7]} {Human: ENSG00000173013, CCDC96, coiled-coil domain containing 96, [RH, Score=195, Expect=5e-54]} {Mouse: ENSMUSG00000050677, Ccdc96, coiled-coil domain containing 96, [RH, Score=195, Expect=4e-54]} {Smed: dd_Smed_v6_9313_0_1, dd_Smed_v6_9313_0_1, [RH, Score=201, Expect=5e-59]} {RNA1509_26742, RNA1509_58369} {RNA1310_8172.1, RNA1509_58369} {RNA1509_58369, RNA815_3762}
71. MligTC455_45263 126 2.63 Mlig455_007141

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_007141 {REF} {Length: 2891} {Smed: dd_Smed_v6_5091_0_1, dd_Smed_v6_5091_0_1, [Score=133, Expect=1e-35]} {RNA1509_54868} {RNA1310_9306} {RNA815_2941.1}

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