Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_16354 | 819 | 17.05 | Mlig455_046738, Mlig455_046828 | Neo: Irradiation Age: Up-Down-Down Regeneration-downregulated TP: -2.365 Regeneration-depleted TP: -2.365 |
RPS6KA1 | Mlig455_046738 {REF} {Length: 889} {Pfam: Protein kinase domain [PF00069.27, score=58.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=30.0]} {Human: ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=168, Expect=6e-49]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=168, Expect=6e-49]; ENSG00000072133, RPS6KA6, ribosomal protein S6 kinase A6, [Score=168, Expect=9e-49]; ENSG00000177189, RPS6KA3, ribosomal protein S6 kinase A3, [Score=167, Expect=3e-48]; ENSG00000071242, RPS6KA2, ribosomal protein S6 kinase A2, [Score=166, Expect=6e-48]} {Mouse: ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=170, Expect=1e-49]; ENSMUSG00000031309, Rps6ka3, ribosomal protein S6 kinase polypeptide 3, [Score=167, Expect=2e-48]; ENSMUSG00000023809, Rps6ka2, ribosomal protein S6 kinase, polypeptide 2, [Score=166, Expect=5e-48]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=163, Expect=4e-47]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=163, Expect=4e-47]} {Dmel: FBgn0262866, S6kII, Ribosomal protein S6 kinase II, [Score=156, Expect=2e-44]} {Celegans: WBGene00011352, rskn-1, Putative ribosomal protein S6 kinase alpha-1, [Score=170, Expect=7e-50]} {Smed: dd_Smed_v6_4316_0_1, dd_Smed_v6_4316_0_1, [Score=154, Expect=3e-44]} {RNA1509_13802} {RNA1310_6706.1} {RNA815_5503} Mlig455_046828 {REF} {Length: 9072} {RNA1509_13802, RNA1509_34330} {RNA1310_6706.1, RNA1509_13802, RNA1509_34330} {RNA1509_13802, RNA1509_34330, RNA815_5503} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.066 | 4.337 | 0.94621 | 1.00000 | |
RegionR2 | 0.003 | 4.337 | 0.99541 | 1.00000 | |
RegionR3 | -0.283 | 4.337 | 0.42747 | 0.94851 | |
RegionR4 | -0.288 | 4.337 | 0.48398 | 0.81149 | |
RegionR5 | -0.655 | 4.337 | 0.05094 | 0.19006 | |
RegionR6 | -0.112 | 4.337 | 0.75060 | 1.00000 | |
RegionR7 | 0.928 | 4.337 | 0.01996 | 0.26192 | |
RegionR8 | 0.473 | 4.337 | 0.37394 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -2.781 | 4.337 | 0.14019 | 0.87672 | |
RegenerationR2 | 0.302 | 4.337 | 0.41045 | 0.82048 | |
RegenerationR3 | 0.403 | 4.337 | 0.31709 | 0.74586 | |
RegenerationR4 | -0.334 | 4.337 | 0.41726 | 0.82439 | |
RegenerationR5 | 0.489 | 4.337 | 0.19606 | 0.62801 | |
RegenerationR6 | -0.417 | 4.337 | 0.32082 | 0.66733 | |
RegenerationBL | -0.36 | 4.337 | 0.42631 | 0.79456 | |
RegenerationTP | -2.365 | 4.337 | 0.00006 | 0.00854 | Specific for TP: -2.365 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_16354 | 819 | 17.05 | Mlig455_046738, Mlig455_046828 | Neo: Irradiation Age: Up-Down-Down Regeneration-downregulated TP: -2.365 Regeneration-depleted TP: -2.365 |
RPS6KA1 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_046738 {REF} {Length: 889} {Pfam: Protein kinase domain [PF00069.27, score=58.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=30.0]} {Human: ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=168, Expect=6e-49]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=168, Expect=6e-49]; ENSG00000072133, RPS6KA6, ribosomal protein S6 kinase A6, [Score=168, Expect=9e-49]; ENSG00000177189, RPS6KA3, ribosomal protein S6 kinase A3, [Score=167, Expect=3e-48]; ENSG00000071242, RPS6KA2, ribosomal protein S6 kinase A2, [Score=166, Expect=6e-48]} {Mouse: ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=170, Expect=1e-49]; ENSMUSG00000031309, Rps6ka3, ribosomal protein S6 kinase polypeptide 3, [Score=167, Expect=2e-48]; ENSMUSG00000023809, Rps6ka2, ribosomal protein S6 kinase, polypeptide 2, [Score=166, Expect=5e-48]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=163, Expect=4e-47]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=163, Expect=4e-47]} {Dmel: FBgn0262866, S6kII, Ribosomal protein S6 kinase II, [Score=156, Expect=2e-44]} {Celegans: WBGene00011352, rskn-1, Putative ribosomal protein S6 kinase alpha-1, [Score=170, Expect=7e-50]} {Smed: dd_Smed_v6_4316_0_1, dd_Smed_v6_4316_0_1, [Score=154, Expect=3e-44]} {RNA1509_13802} {RNA1310_6706.1} {RNA815_5503} Mlig455_046828 {REF} {Length: 9072} {RNA1509_13802, RNA1509_34330} {RNA1310_6706.1, RNA1509_13802, RNA1509_34330} {RNA1509_13802, RNA1509_34330, RNA815_5503} |
2. | MligTC455_41019 | 1125 | 23.44 | Mlig455_021800 | Neo: - Age: logFC(26M/2M)=0.187 |
TRAK1 | 1.798 | - | - | - | - | 0.840 | 0.958 | Mlig455_021800 {REF} {Length: 4662} {TRANSSPLICED} {Pfam: HAP1 N-terminal conserved region [PF04849.15, score=288.6]} {Human: ENSG00000182606, TRAK1, trafficking kinesin protein 1, [RH, Score=276, Expect=6e-78]} {Mouse: ENSMUSG00000032536, Trak1, trafficking protein, kinesin binding 1, [RH, Score=277, Expect=2e-78]} {Dmel: FBgn0262872, milt, milton, [RH, Score=214, Expect=6e-57]} {Celegans: WBGene00020838, trak-1, TRAK1 and TRAK2 related, [RH, Score=84.3, Expect=1e-16]} {Smed: dd_Smed_v6_4847_0_1, dd_Smed_v6_4847_0_1, [RH, Score=268, Expect=2e-76]} {RNA1509_8774} {RNA1310_2299.2} {RNA815_2123} |
3. | MligTC455_43441 | 981 | 20.44 | Mlig455_030636, Mlig455_031007 | Neo: Int S/G2/M Age: - |
1.727 | - | - | - | 0.744 | - | 0.983 | Mlig455_030636 {REF} {Length: 1690} {TRANSSPLICED} {RNA1509_19913, RNA1509_42652, RNA1509_43735} {RNA1310_18465, RNA1509_19913, RNA1509_42652, RNA1509_43735} {RNA1509_19913, RNA1509_42652, RNA1509_43735, RNA815_7582} Mlig455_031007 {REF} {Length: 1871} {TRANSSPLICED} {RNA1509_42652} {RNA1310_18465} {RNA815_7582} |
|
4. | MligTC455_36317 | 545 | 11.35 | Mlig455_025049 | Neo: - Age: - |
GLB1 | 0.968 | - | - | - | - | 0.968 | - | Mlig455_025049 {REF} {Length: 2498} {Pfam: Glycosyl hydrolases family 35 [PF01301.21, score=364.2]; Beta-galactosidase [PF02449.17, score=40.5]; Beta-galactosidase jelly roll domain [PF13364.8, score=31.4]} {Human: ENSG00000170266, GLB1, galactosidase beta 1, [RH, Score=482, Expect=1e-161]} {Mouse: ENSMUSG00000045594, Glb1, galactosidase, beta 1, [RH, Score=491, Expect=1e-165]} {Dmel: FBgn0001089, Gal, beta galactosidase, [RH, Score=412, Expect=7e-135]} {Celegans: WBGene00011832, bgal-1, Beta-galactosidase, [RH, Score=384, Expect=1e-124]} {Smed: dd_Smed_v6_4056_0_1, dd_Smed_v6_4056_0_1, [RH, Score=514, Expect=4e-175]} {RNA1509_37267} {RNA1310_9080.2, RNA1509_37267} {RNA1509_37267, RNA815_6506} |
5. | MligTC455_41161 | 1723 | 35.89 | Mlig455_015003, Mlig455_038650 | Neo: - Age: - Regeneration-upregulated R6: 1.721 Regeneration-enriched R6: 1.721 |
RBBP6 | 0.964 | - | - | - | - | - | 0.964 | Mlig455_015003 {REF} {Length: 3795} {TRANSSPLICED} {Pfam: DWNN domain [PF08783.13, score=49.8]; U-box domain [PF04564.17, score=27.2]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=20.9]; Ring finger domain [PF13639.8, score=20.2]} {Human: ENSG00000122257, RBBP6, RB binding protein 6, ubiquitin ligase, [Score=78.2, Expect=7e-14]} {Mouse: ENSMUSG00000030779, Rbbp6, retinoblastoma binding protein 6, ubiquitin ligase, [Score=78.2, Expect=5e-14]} {Dmel: FBgn0086129, snama, something that sticks like glue, [Score=96.3, Expect=9e-20]} {Celegans: WBGene00009477, rbpl-1, Retinoblastoma Binding Protein Like, [Score=61.6, Expect=3e-09]} {Smed: dd_Smed_v6_6556_0_1, dd_Smed_v6_6556_0_1, [Score=80.1, Expect=3e-15]} {RNA1509_48313, RNA1509_5537} {RNA1310_2775, RNA1509_48313} {RNA1509_48313, RNA815_5708} Mlig455_038650 {REF} {Length: 3834} {TRANSSPLICED} {Pfam: DWNN domain [PF08783.13, score=49.8]; U-box domain [PF04564.17, score=28.5]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=21.8]; Ring finger domain [PF13639.8, score=21.3]} {Human: ENSG00000122257, RBBP6, RB binding protein 6, ubiquitin ligase, [Score=80.9, Expect=1e-14]} {Mouse: ENSMUSG00000030779, Rbbp6, retinoblastoma binding protein 6, ubiquitin ligase, [Score=80.5, Expect=9e-15]} {Dmel: FBgn0086129, snama, something that sticks like glue, [Score=91.3, Expect=3e-18]} {Celegans: WBGene00009477, rbpl-1, Retinoblastoma Binding Protein Like, [Score=62.0, Expect=2e-09]} {Smed: dd_Smed_v6_6556_0_1, dd_Smed_v6_6556_0_1, [RH, Score=85.9, Expect=4e-17]} {RNA1509_5537} {RNA1310_2775} {RNA815_5708} |
6. | MligTC455_23760 | 1776 | 37 | Mlig455_070910 | Neo: - |
CNN3 | 0.963 | - | - | - | - | 0.963 | - | Mlig455_070910 {REF} {Length: 2340} {Pfam: Calponin family repeat [PF00402.20, score=183.7]; Calponin homology (CH) domain [PF00307.33, score=70.1]} {Human: ENSG00000117519, CNN3, calponin 3, [RH, Score=149, Expect=2e-41]; ENSG00000064666, CNN2, calponin 2, [RH, Score=149, Expect=9e-42]} {Mouse: ENSMUSG00000004665, Cnn2, calponin 2, [RH, Score=154, Expect=7e-44]; ENSMUSG00000053931, Cnn3, calponin 3, acidic, [RH, Score=147, Expect=9e-41]} {Dmel: FBgn0035499, Chd64, [Score=119, Expect=6e-32]} {Celegans: WBGene00000777, cpn-1, CPN-1; CalPoNin, [Score=94.4, Expect=8e-23]} {Smed: dd_Smed_v6_333_0_1, dd_Smed_v6_333_0_1, [RH, Score=436, Expect=2e-153]} {RNA1509_2360} {RNA1310_23676} {RNA815_3937.2} |
7. | MligTC455_36948 | 315 | 6.56 | Mlig455_059931 | Neo: - Age: Up-Down-Down |
SLC49A3 | 0.963 | - | - | - | - | - | 0.963 | Mlig455_059931 {REF} {Length: 2637} {TRANSSPLICED} {Pfam: Major Facilitator Superfamily [PF07690.18, score=73.7]} {Human: ENSG00000169026, SLC49A3, solute carrier family 49 member 3, [RH, Score=263, Expect=5e-81]} {Mouse: ENSMUSG00000029490, Mfsd7a, major facilitator superfamily domain containing 7A, [RH, Score=249, Expect=3e-76]} {Dmel: FBgn0033196, CG1358, [Score=145, Expect=4e-38]} {Celegans: WBGene00015181, B0416.5, [RH, Score=234, Expect=6e-71]} {Smed: dd_Smed_v6_5238_0_1, dd_Smed_v6_5238_0_1, [RH, Score=283, Expect=2e-90]} {RNA1509_27866} {RNA1310_16250.1} {RNA815_4804} |
8. | MligTC455_38583 | 41 | 0.85 | Mlig455_062170 | Neo: - Age: - |
0.958 | - | - | - | - | 0.958 | - | Mlig455_062170 {REF} {Length: 1880} {NoTransDecoderORF} {RNA1509_19235} {RNA1310_74271} {RNA815_23984} | |
9. | MligTC455_51884 | 566 | 11.79 | Mlig455_004230 | Neo: - Age: Down-Down-Up |
CCDC93 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_004230 {REF} {Length: 3317} {TRANSSPLICED} {Pfam: CCDC93, coiled-coil domain [PF09762.11, score=190.2]} {Human: ENSG00000125633, CCDC93, coiled-coil domain containing 93, [RH, Score=347, Expect=4e-111]} {Mouse: ENSMUSG00000026339, Ccdc93, coiled-coil domain containing 93, [RH, Score=351, Expect=7e-113]} {Dmel: FBgn0025519, fidipidine, [RH, Score=271, Expect=1e-82]} {Celegans: WBGene00015815, C16A11.2, [RH, Score=93.2, Expect=1e-19]} {Smed: dd_Smed_v6_2519_0_1, dd_Smed_v6_2519_0_1, [RH, Score=295, Expect=9e-92]} {RNA1509_15297} {RNA1310_447.1} {RNA815_4590.1} |
10. | MligTC455_51695 | 429 | 8.93 | Mlig455_011268 | Neo: - Age: Down-Down-Up |
FAM47E | 0.951 | - | - | - | 0.951 | - | - | Mlig455_011268 {REF} {Length: 2157} {Pfam: FAM47 family [PF14642.8, score=51.4]} {Human: ENSG00000189157, FAM47E, family with sequence similarity 47 member E, [RH, Score=137, Expect=1e-35]} {Mouse: ENSMUSG00000078315, Fam47c, family with sequence similarity 47, member C, [RH, Score=119, Expect=5e-29]} {Smed: dd_Smed_v6_10346_0_1, dd_Smed_v6_10346_0_1, [RH, Score=294, Expect=2e-95]} {RNA1509_32582, RNA1509_8031} {RNA1310_12665, RNA1509_32582, RNA1509_8031} {RNA1509_32582, RNA1509_8031, RNA815_4489.1} |