Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_21052 | 277 | 5.78 | Mlig455_057141 | Neo: - Age: - |
KRAS | Mlig455_057141 {REF} {Length: 4831} {Pfam: Ras family [PF00071.24, score=191.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=74.6]; ADP-ribosylation factor family [PF00025.23, score=40.0]; RsgA GTPase [PF03193.18, score=27.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.8]; 50S ribosome-binding GTPase [PF01926.25, score=26.3]} {Human: ENSG00000133703, KRAS, KRAS proto-oncogene, GTPase, [RH, Score=279, Expect=1e-96]; ENSG00000174775, HRAS, HRas proto-oncogene, GTPase, [RH, Score=276, Expect=1e-95]; ENSG00000276536, HRAS, HRas proto-oncogene, GTPase, [RH, Score=276, Expect=1e-95]; ENSG00000213281, NRAS, NRAS proto-oncogene, GTPase, [RH, Score=271, Expect=1e-93]} {Mouse: ENSMUSG00000030265, Kras, Kirsten rat sarcoma viral oncogene homolog, [RH, Score=283, Expect=2e-98]; ENSMUSG00000025499, Hras, Harvey rat sarcoma virus oncogene, [RH, Score=276, Expect=9e-96]; ENSMUSG00000027852, Nras, neuroblastoma ras oncogene, [RH, Score=273, Expect=3e-94]} {Dmel: FBgn0003205, Ras85D, Ras oncogene at 85D, [RH, Score=273, Expect=1e-94]} {Celegans: WBGene00002335, let-60, Ras protein let-60, [RH, Score=264, Expect=5e-91]} {Smed: dd_Smed_v6_2885_0_1, dd_Smed_v6_2885_0_1, [RH, Score=260, Expect=1e-89]} {RNA1509_38188, RNA1509_40550} {RNA1310_45604, RNA1509_40550} {RNA1509_40550, RNA815_23702} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.608 | 2.931 | 0.66985 | 1.00000 | |
RegionR2 | 1.778 | 2.931 | 0.00636 | 0.07514 | |
RegionR3 | 0.985 | 2.931 | 0.05383 | 0.40647 | |
RegionR4 | 0.107 | 2.931 | 0.85860 | 1.00000 | |
RegionR5 | -0.834 | 2.931 | 0.11162 | 0.32881 | |
RegionR6 | -0.041 | 2.931 | 0.94581 | 1.00000 | |
RegionR7 | -0.54 | 2.931 | 0.49415 | 1.00000 | |
RegionR8 | -0.847 | 2.931 | 0.40203 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -5.327 | 2.931 | 0.30839 | 1.00000 | |
RegenerationR2 | -0.438 | 2.931 | 0.38664 | 0.80612 | |
RegenerationR3 | 0.181 | 2.931 | 0.75503 | 0.96610 | |
RegenerationR4 | -1.254 | 2.931 | 0.05187 | 0.36592 | |
RegenerationR5 | 0.039 | 2.931 | 0.95694 | 1.00000 | |
RegenerationR6 | 0.265 | 2.931 | 0.69432 | 0.92155 | |
RegenerationBL | 0.33 | 2.931 | 0.71938 | 1.00000 | |
RegenerationTP | 0.53 | 2.931 | 0.57969 | 0.94958 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_21052 | 277 | 5.78 | Mlig455_057141 | Neo: - Age: - |
KRAS | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_057141 {REF} {Length: 4831} {Pfam: Ras family [PF00071.24, score=191.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=74.6]; ADP-ribosylation factor family [PF00025.23, score=40.0]; RsgA GTPase [PF03193.18, score=27.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.8]; 50S ribosome-binding GTPase [PF01926.25, score=26.3]} {Human: ENSG00000133703, KRAS, KRAS proto-oncogene, GTPase, [RH, Score=279, Expect=1e-96]; ENSG00000174775, HRAS, HRas proto-oncogene, GTPase, [RH, Score=276, Expect=1e-95]; ENSG00000276536, HRAS, HRas proto-oncogene, GTPase, [RH, Score=276, Expect=1e-95]; ENSG00000213281, NRAS, NRAS proto-oncogene, GTPase, [RH, Score=271, Expect=1e-93]} {Mouse: ENSMUSG00000030265, Kras, Kirsten rat sarcoma viral oncogene homolog, [RH, Score=283, Expect=2e-98]; ENSMUSG00000025499, Hras, Harvey rat sarcoma virus oncogene, [RH, Score=276, Expect=9e-96]; ENSMUSG00000027852, Nras, neuroblastoma ras oncogene, [RH, Score=273, Expect=3e-94]} {Dmel: FBgn0003205, Ras85D, Ras oncogene at 85D, [RH, Score=273, Expect=1e-94]} {Celegans: WBGene00002335, let-60, Ras protein let-60, [RH, Score=264, Expect=5e-91]} {Smed: dd_Smed_v6_2885_0_1, dd_Smed_v6_2885_0_1, [RH, Score=260, Expect=1e-89]} {RNA1509_38188, RNA1509_40550} {RNA1310_45604, RNA1509_40550} {RNA1509_40550, RNA815_23702} |
2. | MligTC455_22757 | 125 | 2.61 | Mlig455_002660 | Neo: - Age: - |
2.429 | - | 0.762 | 0.951 | - | 0.716 | - | Mlig455_002660 {REF} {Length: 4866} {TRANSSPLICED} {RNA1509_20135} {RNA1310_8897.1} {RNA815_3545} | |
3. | MligTC455_42886 | 494 | 10.29 | Mlig455_004248 | Neo: - Age: - |
AL136295.1 | 0.966 | - | - | - | - | 0.966 | - | Mlig455_004248 {REF} {Length: 3161} {TRANSSPLICED} {Pfam: Endomembrane protein 70 [PF02990.18, score=493.4]} {Human: ENSG00000254692, AL136295.1, novel protein, [RH, Score=692, Expect=0.0]; ENSG00000285502, AL136295.15, novel protein, [RH, Score=692, Expect=0.0]; ENSG00000100926, TM9SF1, transmembrane 9 superfamily member 1, [RH, Score=685, Expect=0.0]; ENSG00000285465, TM9SF1, transmembrane 9 superfamily member 1, [RH, Score=685, Expect=0.0]} {Mouse: ENSMUSG00000002320, Tm9sf1, transmembrane 9 superfamily member 1, [RH, Score=683, Expect=0.0]} {Dmel: FBgn0035622, TM9SF3, Transmembrane 9 superfamily protein member 3, [Score=332, Expect=3e-106]} {Celegans: WBGene00021506, Y41D4A.4, Transmembrane 9 superfamily member, [Score=346, Expect=9e-112]} {Smed: dd_Smed_v6_4115_0_1, dd_Smed_v6_4115_0_1, [RH, Score=618, Expect=0.0]} {RNA1509_11922, RNA1509_20805, RNA1509_23244, RNA1509_47900, RNA1509_57407} {RNA1310_10868, RNA1509_11922, RNA1509_20805, RNA1509_23244, RNA1509_47900, RNA1509_57407} {RNA1509_11922, RNA1509_20805, RNA1509_23244, RNA1509_47900, RNA1509_57407, RNA815_2853} |
4. | MligTC455_49237 | 1147 | 23.89 | Mlig455_053089 | Neo: - Age: Down-Up-Down |
CAMK4 | 0.966 | - | - | - | - | 0.966 | - | Mlig455_053089 {REF} {Length: 2761} {Pfam: Protein kinase domain [PF00069.27, score=263.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.6]; Fungal protein kinase [PF17667.3, score=24.4]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000152495, CAMK4, calcium/calmodulin dependent protein kinase IV, [Score=351, Expect=4e-118]} {Mouse: ENSMUSG00000038128, Camk4, calcium/calmodulin-dependent protein kinase IV, [Score=353, Expect=3e-119]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=248, Expect=2e-79]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=245, Expect=8e-79]} {Smed: dd_Smed_v6_10731_0_1, dd_Smed_v6_10731_0_1, [Score=357, Expect=1e-122]} {RNA1509_27017, RNA1509_8403} {RNA1310_11195.2, RNA1509_27017, RNA1509_8403} {RNA1509_27017, RNA1509_8403, RNA815_9103.1} |
5. | MligTC455_15526 | 410 | 8.54 | Mlig455_037465, Mlig455_037504 | Neo: - |
0.962 | 0.962 | - | - | - | - | - | Mlig455_037465 {REF} {Length: 2126} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=26.7} {RNA1509_54950} {RNA1310_28080} {RNA815_30352} Mlig455_037504 {REF} {Length: 2131} {TRANSSPLICED} {RNA1509_54950} {RNA1310_28080, RNA1509_54950} {RNA1509_54950, RNA815_30352} |
|
6. | MligTC455_17039 | 24 | 0.5 | Mlig455_025016 | Neo: - Age: - |
0.962 | - | - | 0.962 | - | - | - | Mlig455_025016 {REF} {Length: 2009} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=72.7]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=20.5]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=18.8]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [RH, Score=209, Expect=1e-63]} {RNA1310_42205} {RNA815_15017} | |
7. | MligTC455_22918 | 48 | 0.99 | Mlig455_024197 | Neo: - Age: - |
0.962 | - | - | 0.962 | - | - | - | Mlig455_024197 {REF} {Length: 882} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_24504} {RNA1310_56956} {RNA815_52770} | |
8. | MligTC455_34249 | 231 | 4.81 | Mlig455_062909 | Neo: Int S/G2/M Age: Up-Down-Down |
YTHDC2 | 0.96 | - | 0.960 | - | - | - | - | Mlig455_062909 {REF} {Length: 6356} {TRANSSPLICED} {Pfam: Helicase associated domain (HA2) [PF04408.25, score=67.8]; Helicase conserved C-terminal domain [PF00271.33, score=48.5]; Oligonucleotide/oligosaccharide-binding (OB)-fold [PF07717.18, score=39.3]; R3H domain [PF01424.24, score=36.0]; AAA domain [PF13245.8, score=29.1]; KaiC [PF06745.15, score=20.4]} {Human: ENSG00000047188, YTHDC2, YTH domain containing 2, [RH, Score=917, Expect=0.0]} {Mouse: ENSMUSG00000034653, Ythdc2, YTH domain containing 2, [RH, Score=928, Expect=0.0]} {Dmel: FBgn0004581, bgcn, benign gonial cell neoplasm, [RH, Score=259, Expect=5e-70]} {Celegans: WBGene00009922, F52B5.3, [RH, Score=212, Expect=4e-55]} {Smed: dd_Smed_v6_4815_0_1, dd_Smed_v6_4815_0_1, [Score=214, Expect=7e-56]} {RNA1509_15401} {RNA1310_1583.1} {RNA815_6960} |
9. | MligTC455_41881 | 799 | 16.64 | Mlig455_011980, Mlig455_068626 | Neo: - Age: - |
FGFR1OP | 0.959 | - | - | - | - | 0.959 | - | Mlig455_011980 {REF} {Length: 2999} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=38.9]; LisH [PF16045.7, score=17.6]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=101, Expect=4e-23]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=99.4, Expect=2e-22]} {Smed: dd_Smed_v6_5371_0_1, dd_Smed_v6_5371_0_1, [Score=58.2, Expect=3e-09]} {RNA1509_14615} {RNA1310_13253.1} {RNA815_34617.1} Mlig455_068626 {REF} {Length: 2876} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=39.1]; LisH [PF16045.7, score=17.8]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=104, Expect=3e-24]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=99.4, Expect=1e-22]} {Smed: dd_Smed_v6_5371_0_2, dd_Smed_v6_5371_0_2, [Score=57.8, Expect=2e-09]} {RNA1509_14615} {RNA1310_14786, RNA1509_14615} {RNA1509_14615, RNA815_10750} |
10. | MligTC455_50422 | 125 | 2.6 | Mlig455_014719 | Neo: - Age: - Region-enriched R2: 3.621/0.01085 |
GALNT1 | 0.959 | - | - | - | - | - | 0.959 | Mlig455_014719 {REF} {Length: 2844} {Pfam: Glycosyl transferase family 2 [PF00535.28, score=108.6]; N-terminal domain of galactosyltransferase [PF02709.16, score=19.9]} {Human: ENSG00000141429, GALNT1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=328, Expect=8e-108]; ENSG00000144278, GALNT13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=320, Expect=1e-102]} {Mouse: ENSMUSG00000000420, Galnt1, polypeptide N-acetylgalactosaminyltransferase 1, [Score=328, Expect=7e-106]; ENSMUSG00000060988, Galnt13, polypeptide N-acetylgalactosaminyltransferase 13, [Score=320, Expect=9e-103]} {Dmel: FBgn0050463, CG30463, [Score=349, Expect=3e-113]} {Celegans: WBGene00001630, gly-5, Polypeptide N-acetylgalactosaminyltransferase 5, [Score=359, Expect=2e-117]} {Smed: dd_Smed_v6_4615_0_1, dd_Smed_v6_4615_0_1, [Score=379, Expect=3e-125]} {RNA1509_29632} {RNA1310_10752} {RNA815_14192.1} |
11. | MligTC455_24921 | 169 | 3.53 | Mlig455_055130, Mlig455_064022, Mlig455_068594 | Neo: - Age: - |
0.958 | - | - | 0.958 | - | - | - | Mlig455_055130 {REF} {Length: 5554} {Mouse: ENSMUSG00000079051, Gm14025, predicted gene 14025, [Score=58.9, Expect=6e-08]} {RNA1509_36794, RNA1509_45848} {RNA1310_3132.1, RNA1509_45848} {RNA1509_45848, RNA815_9224} Mlig455_064022 {REF} {Length: 5554} {Mouse: ENSMUSG00000079051, Gm14025, predicted gene 14025, [Score=58.5, Expect=7e-08]} {RNA1509_36794} {RNA1310_3132.1} {RNA815_9224} Mlig455_068594 {REF} {Length: 4836} {Pfam: Vinculin family [PF01044.21, score=20.7]} {RNA1509_36794} {RNA1310_3132.1} {RNA815_9224} |
|
12. | MligTC455_28822 | 88 | 1.84 | Mlig455_035721 | Neo: - Age: - |
0.957 | - | - | 0.957 | - | - | - | Mlig455_035721 {REF} {Length: 778} {RNA1509_5701} {RNA1310_28426} {RNA815_453.1} | |
13. | MligTC455_23626 | 339 | 7.06 | Mlig455_065292, Mlig455_065316 | Neo: - Age: - |
KIAA0930 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_065292 {REF} {Length: 5359} {Pfam: Uncharacterized conserved protein (DUF2045) [PF09741.11, score=220.5]} {Human: ENSG00000100364, KIAA0930, KIAA0930, [RH, Score=216, Expect=2e-62]} {Mouse: ENSMUSG00000036046, 5031439G07Rik, RIKEN cDNA 5031439G07 gene, [RH, Score=207, Expect=8e-59]} {Dmel: FBgn0034184, CG9646, [RH, Score=264, Expect=5e-80]} {Celegans: WBGene00015866, C16E9.2, [Score=222, Expect=2e-64]} {Smed: dd_Smed_v6_6401_0_1, dd_Smed_v6_6401_0_1, [Score=268, Expect=2e-81]} {RNA1509_45284} {RNA1310_9456.1, RNA1509_45284} {RNA1509_45284, RNA815_27690} Mlig455_065316 {REF} {Length: 4497} {Pfam: Uncharacterized conserved protein (DUF2045) [PF09741.11, score=221.3]} {Human: ENSG00000100364, KIAA0930, KIAA0930, [RH, Score=218, Expect=5e-64]} {Mouse: ENSMUSG00000036046, 5031439G07Rik, RIKEN cDNA 5031439G07 gene, [RH, Score=208, Expect=4e-60]} {Dmel: FBgn0034184, CG9646, [RH, Score=268, Expect=4e-83]} {Celegans: WBGene00015866, C16E9.2, [Score=225, Expect=1e-66]} {Smed: dd_Smed_v6_6401_0_1, dd_Smed_v6_6401_0_1, [Score=271, Expect=5e-84]} {RNA1509_45284, RNA1509_51132, RNA1509_52104} {RNA1310_9456.1, RNA1509_51132, RNA1509_52104} {RNA1509_51132, RNA1509_52104, RNA815_27690} |
14. | MligTC455_42464 | 2032 | 42.34 | Mlig455_050103, Mlig455_054011 | Neo: Int S/G2/M Age: Down-Up-Up, logFC(26M/2M)=0.342 Region-enriched R4: 1.128/0.00501 |
MALSU1 | 0.955 | - | - | - | - | 0.955 | - | Mlig455_050103 {REF} {Length: 1000} {TRANSSPLICED} {Pfam: Ribosomal silencing factor during starvation [PF02410.17, score=49.8]} {Human: ENSG00000156928, MALSU1, mitochondrial assembly of ribosomal large subunit 1, [RH, Score=68.2, Expect=7e-13]} {Mouse: ENSMUSG00000029815, Malsu1, mitochondrial assembly of ribosomal large subunit 1, [RH, Score=66.6, Expect=1e-12]} {Dmel: FBgn0029514, 312, [RH, Score=103, Expect=3e-26]} {Smed: dd_Smed_v6_6821_0_1, dd_Smed_v6_6821_0_1, [RH, Score=85.9, Expect=6e-20]} {RNA1509_12171} {RNA1310_35117} {RNA815_16541} Mlig455_054011 {REF} {Length: 1009} {TRANSSPLICED} {Pfam: Ribosomal silencing factor during starvation [PF02410.17, score=48.5]} {Human: ENSG00000156928, MALSU1, mitochondrial assembly of ribosomal large subunit 1, [RH, Score=68.2, Expect=6e-13]} {Mouse: ENSMUSG00000029815, Malsu1, mitochondrial assembly of ribosomal large subunit 1, [RH, Score=65.9, Expect=3e-12]} {Dmel: FBgn0029514, 312, [RH, Score=103, Expect=3e-26]} {Smed: dd_Smed_v6_6821_0_1, dd_Smed_v6_6821_0_1, [RH, Score=85.1, Expect=1e-19]} {RNA1509_12171} {RNA1310_35117, RNA1509_12171} {RNA1509_12171, RNA815_16541} |
15. | MligTC455_41979 | 3503 | 72.98 | Mlig455_022271 | Neo: - Age: logFC(26M/2M)=-0.319 |
0.954 | - | - | - | - | 0.954 | - | Mlig455_022271 {REF} {Length: 3465} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_35371, RNA1509_3710, RNA1509_5489} {RNA1310_15598, RNA1509_35371, RNA1509_3710, RNA1509_5489} {RNA1509_35371, RNA1509_3710, RNA1509_5489, RNA815_10198.1} | |
16. | MligTC455_51341 | 572 | 11.91 | Mlig455_031577 | Neo: - Age: Down-Up-Down |
DYRK1B | 0.953 | - | - | - | - | 0.953 | - | Mlig455_031577 {REF} {Length: 4639} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=173.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.6]} {Human: ENSG00000281320, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [RH, Score=548, Expect=0.0]; ENSG00000105204, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000002409, Dyrk1b, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b, [RH, Score=550, Expect=0.0]} {Dmel: FBgn0259168, mnb, minibrain, [RH, Score=555, Expect=0.0]} {Celegans: WBGene00003149, mbk-1, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1, [RH, Score=477, Expect=1e-155]} {Smed: dd_Smed_v6_3773_0_1, dd_Smed_v6_3773_0_1, [RH, Score=464, Expect=7e-148]} {RNA1509_5357} {RNA1310_1355.1} {RNA815_1613.1} |