Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_34249 | 231 | 4.81 | Mlig455_062909 | Neo: Int S/G2/M Age: Up-Down-Down |
YTHDC2 | Mlig455_062909 {REF} {Length: 6356} {TRANSSPLICED} {Pfam: Helicase associated domain (HA2) [PF04408.25, score=67.8]; Helicase conserved C-terminal domain [PF00271.33, score=48.5]; Oligonucleotide/oligosaccharide-binding (OB)-fold [PF07717.18, score=39.3]; R3H domain [PF01424.24, score=36.0]; AAA domain [PF13245.8, score=29.1]; KaiC [PF06745.15, score=20.4]} {Human: ENSG00000047188, YTHDC2, YTH domain containing 2, [RH, Score=917, Expect=0.0]} {Mouse: ENSMUSG00000034653, Ythdc2, YTH domain containing 2, [RH, Score=928, Expect=0.0]} {Dmel: FBgn0004581, bgcn, benign gonial cell neoplasm, [RH, Score=259, Expect=5e-70]} {Celegans: WBGene00009922, F52B5.3, [RH, Score=212, Expect=4e-55]} {Smed: dd_Smed_v6_4815_0_1, dd_Smed_v6_4815_0_1, [Score=214, Expect=7e-56]} {RNA1509_15401} {RNA1310_1583.1} {RNA815_6960} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.06 | 2.789 | 0.97433 | 1.00000 | |
RegionR2 | 0.745 | 2.789 | 0.33149 | 0.72341 | |
RegionR3 | 0.02 | 2.789 | 0.97042 | 1.00000 | |
RegionR4 | 1.415 | 2.789 | 0.04236 | 0.17219 | |
RegionR5 | 0.638 | 2.789 | 0.24459 | 0.55776 | |
RegionR6 | -0.966 | 2.789 | 0.17578 | 0.73689 | |
RegionR7 | -1.518 | 2.789 | 0.12758 | 0.67282 | |
RegionR8 | -0.275 | 2.789 | 0.77446 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -5.315 | 2.789 | 0.33090 | 1.00000 | |
RegenerationR2 | -0.618 | 2.789 | 0.31618 | 0.75478 | |
RegenerationR3 | 0.506 | 2.789 | 0.48245 | 0.85164 | |
RegenerationR4 | -0.233 | 2.789 | 0.75259 | 0.97037 | |
RegenerationR5 | 0.448 | 2.789 | 0.48914 | 0.85174 | |
RegenerationR6 | 0.821 | 2.789 | 0.33080 | 0.67720 | |
RegenerationBL | 0.411 | 2.789 | 0.70613 | 1.00000 | |
RegenerationTP | 1.279 | 2.789 | 0.17116 | 0.60394 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_34249 | 231 | 4.81 | Mlig455_062909 | Neo: Int S/G2/M Age: Up-Down-Down |
YTHDC2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_062909 {REF} {Length: 6356} {TRANSSPLICED} {Pfam: Helicase associated domain (HA2) [PF04408.25, score=67.8]; Helicase conserved C-terminal domain [PF00271.33, score=48.5]; Oligonucleotide/oligosaccharide-binding (OB)-fold [PF07717.18, score=39.3]; R3H domain [PF01424.24, score=36.0]; AAA domain [PF13245.8, score=29.1]; KaiC [PF06745.15, score=20.4]} {Human: ENSG00000047188, YTHDC2, YTH domain containing 2, [RH, Score=917, Expect=0.0]} {Mouse: ENSMUSG00000034653, Ythdc2, YTH domain containing 2, [RH, Score=928, Expect=0.0]} {Dmel: FBgn0004581, bgcn, benign gonial cell neoplasm, [RH, Score=259, Expect=5e-70]} {Celegans: WBGene00009922, F52B5.3, [RH, Score=212, Expect=4e-55]} {Smed: dd_Smed_v6_4815_0_1, dd_Smed_v6_4815_0_1, [Score=214, Expect=7e-56]} {RNA1509_15401} {RNA1310_1583.1} {RNA815_6960} |
2. | MligTC455_24191 | 167 | 3.47 | Mlig455_036990 | Neo: - Age: logFC(26M/2M)=0.434 Region-enriched R5: 2.098/0.03929 |
GCKR | 1.757 | - | 0.791 | - | - | 0.966 | - | Mlig455_036990 {REF} {Length: 3658} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=29.6]} {Human: ENSG00000084734, GCKR, glucokinase regulator, [RH, Score=150, Expect=6e-37]} {Mouse: ENSMUSG00000059434, Gckr, glucokinase regulatory protein, [RH, Score=146, Expect=7e-36]} {Dmel: FBgn0259789, zld, zelda, [Score=54.7, Expect=6e-07]} {Celegans: WBGene00003847, blmp-1, B lymphocyte-induced maturation protein 1 homolog, [Score=65.1, Expect=2e-10]} {Smed: dd_Smed_v6_5558_0_1, dd_Smed_v6_5558_0_1, [RH, Score=75.5, Expect=3e-14]} {RNA1509_51386} {RNA1310_15402} {RNA815_4323.1} |
3. | MligTC455_40173 | 468 | 9.75 | Mlig455_015114 | Neo: - Age: - |
0.967 | - | - | - | 0.967 | - | - | Mlig455_015114 {REF} {Length: 5090} {Pfam: 3-Ketosteroid 9alpha-hydroxylase C-terminal domain [PF19298.1, score=142.0]; Rieske [2Fe-2S] domain [PF00355.28, score=64.7]; Rieske-like [2Fe-2S] domain [PF13806.8, score=23.0]} {Dmel: FBgn0259697, nvd, neverland, [RH, Score=275, Expect=3e-88]} {Celegans: WBGene00007536, daf-36, Cholesterol 7-desaturase, [RH, Score=290, Expect=2e-94]} {RNA1509_48820} {RNA1310_10609} {RNA815_10029} | |
4. | MligTC455_51995 | 773 | 16.1 | Mlig455_009690, Mlig455_063052 | Neo: - |
SMAD3 | 0.965 | - | - | - | 0.965 | - | - | Mlig455_009690 {REF} {Length: 4845} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=208.1]; MH1 domain [PF03165.18, score=81.1]} {Human: ENSG00000166949, SMAD3, SMAD family member 3, [Score=335, Expect=6e-111]; ENSG00000175387, SMAD2, SMAD family member 2, [Score=329, Expect=9e-109]; ENSG00000120693, SMAD9, SMAD family member 9, [Score=325, Expect=1e-106]; ENSG00000170365, SMAD1, SMAD family member 1, [Score=319, Expect=2e-104]} {Mouse: ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=335, Expect=4e-111]; ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=329, Expect=6e-109]; ENSMUSG00000031681, Smad1, SMAD family member 1, [Score=322, Expect=2e-105]} {Dmel: FBgn0011648, Mad, Mothers against dpp, [Score=330, Expect=3e-109]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=198, Expect=1e-58]} {Smed: dd_Smed_v6_6050_0_1, dd_Smed_v6_6050_0_1, [Score=326, Expect=2e-108]} {RNA1509_16626, RNA1509_22400} {RNA1310_23806, RNA1509_16626, RNA1509_22400} {RNA1509_16626, RNA1509_22400, RNA815_18514} Mlig455_063052 {REF} {Length: 4507} {TRANSSPLICED} {Pfam: MH2 domain [PF03166.16, score=208.0]; MH1 domain [PF03165.18, score=81.2]} {Human: ENSG00000166949, SMAD3, SMAD family member 3, [Score=330, Expect=5e-109]; ENSG00000175387, SMAD2, SMAD family member 2, [Score=325, Expect=1e-106]; ENSG00000120693, SMAD9, SMAD family member 9, [Score=323, Expect=8e-106]; ENSG00000170365, SMAD1, SMAD family member 1, [Score=315, Expect=1e-102]} {Mouse: ENSMUSG00000032402, Smad3, SMAD family member 3, [Score=330, Expect=3e-109]; ENSMUSG00000024563, Smad2, SMAD family member 2, [Score=325, Expect=7e-107]; ENSMUSG00000031681, Smad1, SMAD family member 1, [Score=316, Expect=4e-103]} {Dmel: FBgn0011648, Mad, Mothers against dpp, [Score=325, Expect=7e-107]} {Celegans: WBGene00004856, sma-2, Dwarfin sma-2, [Score=198, Expect=1e-58]} {Smed: dd_Smed_v6_6877_0_1, dd_Smed_v6_6877_0_1, [Score=306, Expect=9e-100]} {RNA1509_16668} {RNA1310_40116.1} {RNA815_18514} |
5. | MligTC455_34289 | 160 | 3.33 | Mlig455_041808 | Neo: - Age: - Region-enriched R5: 2.798/0.00006 |
RUNDC3B | 0.961 | - | - | - | 0.961 | - | - | Mlig455_041808 {REF} {Length: 3837} {TRANSSPLICED} {Pfam: RUN domain [PF02759.21, score=36.7]} {Human: ENSG00000105784, RUNDC3B, RUN domain containing 3B, [RH, Score=106, Expect=5e-24]} {Mouse: ENSMUSG00000040570, Rundc3b, RUN domain containing 3B, [RH, Score=105, Expect=1e-23]; ENSMUSG00000006575, Rundc3a, RUN domain containing 3A, [RH, Score=100, Expect=2e-22]} {Dmel: FBgn0051064, CG31064, [Score=59.3, Expect=6e-09]} {Smed: dd_Smed_v6_12008_0_1, dd_Smed_v6_12008_0_1, [RH, Score=97.4, Expect=3e-21]} {RNA1509_59598} {RNA1310_25993, RNA1509_59598} {RNA1509_59598, RNA815_6485} |
6. | MligTC455_21052 | 277 | 5.78 | Mlig455_057141 | Neo: - Age: - |
KRAS | 0.96 | - | 0.960 | - | - | - | - | Mlig455_057141 {REF} {Length: 4831} {Pfam: Ras family [PF00071.24, score=191.4]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=74.6]; ADP-ribosylation factor family [PF00025.23, score=40.0]; RsgA GTPase [PF03193.18, score=27.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=26.8]; 50S ribosome-binding GTPase [PF01926.25, score=26.3]} {Human: ENSG00000133703, KRAS, KRAS proto-oncogene, GTPase, [RH, Score=279, Expect=1e-96]; ENSG00000174775, HRAS, HRas proto-oncogene, GTPase, [RH, Score=276, Expect=1e-95]; ENSG00000276536, HRAS, HRas proto-oncogene, GTPase, [RH, Score=276, Expect=1e-95]; ENSG00000213281, NRAS, NRAS proto-oncogene, GTPase, [RH, Score=271, Expect=1e-93]} {Mouse: ENSMUSG00000030265, Kras, Kirsten rat sarcoma viral oncogene homolog, [RH, Score=283, Expect=2e-98]; ENSMUSG00000025499, Hras, Harvey rat sarcoma virus oncogene, [RH, Score=276, Expect=9e-96]; ENSMUSG00000027852, Nras, neuroblastoma ras oncogene, [RH, Score=273, Expect=3e-94]} {Dmel: FBgn0003205, Ras85D, Ras oncogene at 85D, [RH, Score=273, Expect=1e-94]} {Celegans: WBGene00002335, let-60, Ras protein let-60, [RH, Score=264, Expect=5e-91]} {Smed: dd_Smed_v6_2885_0_1, dd_Smed_v6_2885_0_1, [RH, Score=260, Expect=1e-89]} {RNA1509_38188, RNA1509_40550} {RNA1310_45604, RNA1509_40550} {RNA1509_40550, RNA815_23702} |
7. | MligTC455_21208 | 406 | 8.45 | Mlig455_024309, Mlig455_024366 | Neo: - Age: Up-Down-Down |
0.958 | - | - | - | 0.958 | - | - | Mlig455_024309 {REF} {Length: 4285} {TRANSSPLICED} {Pfam: Apoptosis regulator proteins, Bcl-2 family [PF00452.21, score=27.0]} {RNA1509_18836} {RNA1310_11496.1, RNA1509_18836} {RNA1509_18836, RNA815_20761} Mlig455_024366 {REF} {Length: 3750} {TRANSSPLICED} {Pfam: Apoptosis regulator proteins, Bcl-2 family [PF00452.21, score=26.3]} {RNA1509_18836} {RNA1310_14991} {RNA815_20761} |
|
8. | MligTC455_39051 | 649 | 13.51 | Mlig455_009777, Mlig455_054926 | Neo: - Age: - |
0.958 | - | - | - | 0.958 | - | - | Mlig455_009777 {REF} {Length: 1081} {NoTransDecoderORF} {RNA1509_31588, RNA1509_38997} {RNA1310_28624.1, RNA1509_31588, RNA1509_38997} {RNA1509_31588, RNA1509_38997, RNA815_15427} Mlig455_054926 {REF} {Length: 1048} {NoTransDecoderORF} {RNA1509_38997} {RNA1310_28624.1} {RNA815_15427} |
|
9. | MligTC455_37950 | 513 | 10.69 | Mlig455_005135, Mlig455_005174 | Neo: Irradiation Age: Up-Down-Down, logFC(26M/2M)=-0.327 Region-specific R4: 5.190 Region-enriched R4: 2.389/0.00420 |
0.956 | - | - | - | 0.956 | - | - | Mlig455_005135 {REF} {Length: 3184} {TRANSSPLICED} {RNA1509_45459, RNA1509_6001} {RNA1310_4679, RNA1509_45459, RNA1509_6001} {RNA1509_45459, RNA1509_6001, RNA815_3503} Mlig455_005174 {REF} {Length: 3060} {TRANSSPLICED} {RNA1509_6001} {RNA1310_4679} {RNA815_3503} |
|
10. | MligTC455_32831 | 609 | 12.68 | Mlig455_026495 | Neo: - Age: - |
POLR3B | 0.955 | 0.955 | - | - | - | - | - | Mlig455_026495 {REF} {Length: 3723} {TRANSSPLICED} {Pfam: RNA polymerase Rpb2, domain 6 [PF00562.30, score=410.9]; RNA polymerase Rpb2, domain 7 [PF04560.22, score=110.5]; RNA polymerase beta subunit [PF04563.17, score=94.6]; RNA polymerase Rpb2, domain 4 [PF04566.15, score=77.8]; RNA polymerase Rpb2, domain 3 [PF04565.18, score=77.5]; RNA polymerase Rpb2, domain 2 [PF04561.16, score=75.0]; RNA polymerase Rpb2, domain 5 [PF04567.19, score=39.2]} {Human: ENSG00000013503, POLR3B, RNA polymerase III subunit B, [RH, Score=1358, Expect=0.0]} {Mouse: ENSMUSG00000034453, Polr3b, polymerase (RNA) III (DNA directed) polypeptide B, [RH, Score=1357, Expect=0.0]} {Dmel: FBgn0004463, RpIII128, RNA polymerase III 128kD subunit, [RH, Score=1223, Expect=0.0]} {Celegans: WBGene00017300, rpc-2, DNA-directed RNA polymerase subunit beta, [RH, Score=1212, Expect=0.0]} {Smed: dd_Smed_v6_5517_0_1, dd_Smed_v6_5517_0_1, [RH, Score=864, Expect=0.0]} {RNA1509_14101, RNA1509_28477} {RNA1310_2096, RNA1509_14101, RNA1509_28477} {RNA1509_14101, RNA1509_28477, RNA815_877.1} |
11. | MligTC455_39362 | 1158 | 24.13 | Mlig455_069375 | Neo: - Age: - |
0.954 | - | - | - | 0.954 | - | - | Mlig455_069375 {REF} {Length: 2263} {TRANSSPLICED} {RNA1509_21193} {RNA1310_18941} {RNA815_22823} | |
12. | MligTC455_23397 | 526 | 10.95 | Mlig455_009066 | Neo: - Age: logFC(26M/2M)=0.589 |
NGLY1 | 0.951 | - | - | - | 0.951 | - | - | Mlig455_009066 {REF} {Length: 4333} {Pfam: PNGase C-terminal domain, mannose-binding module PAW [PF04721.19, score=209.7]; PUB domain [PF09409.12, score=60.6]; Transglutaminase-like superfamily [PF01841.21, score=47.8]; Rad4 transglutaminase-like domain [PF03835.17, score=47.2]; Thioredoxin [PF00085.22, score=44.9]; Thioredoxin-like domain [PF13098.8, score=19.1]} {Human: ENSG00000151092, NGLY1, N-glycanase 1, [RH, Score=399, Expect=3e-126]} {Mouse: ENSMUSG00000021785, Ngly1, N-glycanase 1, [RH, Score=417, Expect=4e-133]} {Dmel: FBgn0033050, Pngl, PNGase-like, [RH, Score=307, Expect=3e-92]} {Celegans: WBGene00010160, png-1, Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, [RH, Score=263, Expect=2e-76]} {Smed: dd_Smed_v6_5705_0_1, dd_Smed_v6_5705_0_1, [RH, Score=286, Expect=2e-83]} {RNA1509_9974} {RNA1310_3958} {RNA815_834.1} |