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Results for MligTC455_21264

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_21264 2714 56.54 Mlig455_001276

Neo: Neoblast, stringent

Age: Down-Up-Up, logFC(26M/2M)=0.227

Regeneration-upregulated BL: 1.397

Regeneration-enriched BL: 1.397

HMGB1 Mlig455_001276 {REF} {Length: 1258} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=123.1]; HMG-box domain [PF09011.12, score=117.6]} {Human: ENSG00000189403, HMGB1, high mobility group box 1, [RH, Score=177, Expect=4e-56]} {Mouse: ENSMUSG00000066551, Hmgb1, high mobility group box 1, [RH, Score=178, Expect=2e-56]} {Dmel: FBgn0278608, Dsp1, Dorsal switch protein 1, [Score=207, Expect=6e-66]} {Celegans: WBGene00001972, hmg-1.2, High mobility group protein 1.2, [RH, Score=155, Expect=2e-47]} {Smed: dd_Smed_v6_1331_0_1, dd_Smed_v6_1331_0_1, [Score=221, Expect=1e-72]} {RNA1509_27206, RNA1509_29453, RNA1509_4386} {RNA1310_23719, RNA1509_27206, RNA1509_29453, RNA1509_4386} {RNA1509_27206, RNA1509_29453, RNA1509_4386, RNA815_12466.2}

Cumulative graph for MligTC455_21264

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.479 5.935 0.07030 0.59430
RegionR2 -0.135 5.935 0.72130 1.00000
RegionR3 0.112 5.935 0.72763 1.00000
RegionR4 0.175 5.935 0.63940 0.94532
RegionR5 0.492 5.935 0.10449 0.31423
RegionR6 0.1 5.935 0.75876 1.00000
RegionR7 0.831 5.935 0.01431 0.21435
RegionR8 -0.096 5.935 0.83786 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.174 5.935 0.87928 1.00000
RegenerationR2 -0.186 5.935 0.60513 0.91751
RegenerationR3 0.494 5.935 0.18366 0.61965
RegenerationR4 0.57 5.935 0.13707 0.55740
RegenerationR5 0.417 5.935 0.24467 0.67790
RegenerationR6 1.017 5.935 0.00724 0.10426
RegenerationBL 1.397 5.935 0.00003 0.00165 Specific for BL: 1.397
RegenerationTP 0.989 5.935 0.00894 0.15969


Genes with expression patterns similar to MligTC455_21264

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_21264 2714 56.54 Mlig455_001276

Neo: Neoblast, stringent

Age: Down-Up-Up, logFC(26M/2M)=0.227

Regeneration-upregulated BL: 1.397

Regeneration-enriched BL: 1.397

HMGB1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_001276 {REF} {Length: 1258} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=123.1]; HMG-box domain [PF09011.12, score=117.6]} {Human: ENSG00000189403, HMGB1, high mobility group box 1, [RH, Score=177, Expect=4e-56]} {Mouse: ENSMUSG00000066551, Hmgb1, high mobility group box 1, [RH, Score=178, Expect=2e-56]} {Dmel: FBgn0278608, Dsp1, Dorsal switch protein 1, [Score=207, Expect=6e-66]} {Celegans: WBGene00001972, hmg-1.2, High mobility group protein 1.2, [RH, Score=155, Expect=2e-47]} {Smed: dd_Smed_v6_1331_0_1, dd_Smed_v6_1331_0_1, [Score=221, Expect=1e-72]} {RNA1509_27206, RNA1509_29453, RNA1509_4386} {RNA1310_23719, RNA1509_27206, RNA1509_29453, RNA1509_4386} {RNA1509_27206, RNA1509_29453, RNA1509_4386, RNA815_12466.2}
2. MligTC455_38319 7028 146.41 Mlig455_028523, Mlig455_061508

Neo: Neoblast, stringent

Age: -

Region-enriched R4: 1.249/0.00002

HMGB1 1.819 - - - 0.868 - 0.951

Mlig455_028523 {REF} {Length: 4694} {Pfam: HMG (high mobility group) box [PF00505.21, score=130.7]; HMG-box domain [PF09011.12, score=110.0]} {Human: ENSG00000189403, HMGB1, high mobility group box 1, [Score=167, Expect=8e-52]; ENSG00000164104, HMGB2, high mobility group box 2, [Score=161, Expect=1e-49]} {Mouse: ENSMUSG00000066551, Hmgb1, high mobility group box 1, [RH, Score=162, Expect=1e-50]} {Dmel: FBgn0278608, Dsp1, Dorsal switch protein 1, [Score=187, Expect=3e-58]} {Celegans: WBGene00001972, hmg-1.2, High mobility group protein 1.2, [Score=147, Expect=2e-44]} {Smed: dd_Smed_v6_1331_0_1, dd_Smed_v6_1331_0_1, [RH, Score=237, Expect=5e-79]} {RNA1509_561} {RNA1310_15889.1, RNA1509_561} {RNA1509_561, RNA815_4632}

Mlig455_061508 {REF} {Length: 224} {NoTransDecoderORF} {RNA1509_51801} {RNA1310_47956} {RNA815_8157}
3. MligTC455_22375 192 3.99 Mlig455_043243

Neo: -

Age: -

1.688 - - - 0.711 - 0.977 Mlig455_043243 {REF} {Length: 1433} {RNA1509_59906} {RNA1310_29774.1} {RNA815_14384.1}
4. MligTC455_14588 675 14.07 Mlig455_063648

Neo: Int S/G2/M

Age: -

CSRP2 1.675 - 0.714 - 0.961 - - Mlig455_063648 {REF} {Length: 2954} {TRANSSPLICED} {Pfam: LIM domain [PF00412.24, score=93.5]; Zinc finger, C3HC4 type (RING finger) [PF17121.7, score=22.2]} {Human: ENSG00000175183, CSRP2, cysteine and glycine rich protein 2, [RH, Score=159, Expect=5e-49]} {Mouse: ENSMUSG00000020186, Csrp2, cysteine and glycine-rich protein 2, [RH, Score=159, Expect=2e-49]} {Dmel: FBgn0014863, Mlp84B, Muscle LIM protein at 84B, [Score=117, Expect=8e-31]} {Celegans: WBGene00003375, mlp-1, MLP/CRP family (Muscle LIM Protein/Cysteine-rich Protein), [Score=76.3, Expect=3e-18]} {Smed: dd_Smed_v6_373_0_1, dd_Smed_v6_373_0_1, [Score=98.2, Expect=1e-25]} {RNA1509_57252} {RNA1310_45023.1} {RNA815_22368}
5. MligTC455_37566 487 10.15 Mlig455_012335

Neo: -

Age: -

Region-enriched R4: 2.321/0.00580
Region-enriched R5: 2.072/0.00095

MPV17L2 0.971 - - - 0.971 - - Mlig455_012335 {REF} {Length: 970} {Pfam: Mpv17 / PMP22 family [PF04117.14, score=64.5]} {Human: ENSG00000254858, MPV17L2, MPV17 mitochondrial inner membrane protein like 2, [Score=97.8, Expect=8e-25]} {Mouse: ENSMUSG00000035559, Mpv17l2, MPV17 mitochondrial membrane protein-like 2, [Score=93.6, Expect=2e-23]; ENSMUSG00000111476, Mpv17l2, MPV17 mitochondrial membrane protein-like 2, [Score=93.6, Expect=2e-23]} {Dmel: FBgn0030481, CG1662, [Score=112, Expect=2e-30]} {Celegans: WBGene00022744, ZK470.1, [Score=73.9, Expect=2e-16]} {Smed: dd_Smed_v6_13953_0_1, dd_Smed_v6_13953_0_1, [Score=54.3, Expect=3e-09]} {RNA1509_35977, RNA1509_58154} {RNA1310_39934, RNA1509_35977, RNA1509_58154} {RNA1509_35977, RNA1509_58154, RNA815_18530.1}
6. MligTC455_15709 325 6.77 Mlig455_061098

Neo: -

Age: -

Region-enriched R5: 2.073/0.01230

0.966 - - - 0.966 - - Mlig455_061098 {REF} {Length: 2452} {TRANSSPLICED} {RNA1509_16670} {RNA1310_43432} {RNA815_21351}
7. MligTC455_23608 188 3.91 Mlig455_034794, Mlig455_063165

Neo: -

Age: -

ANK1 0.955 - - - - 0.955 -

Mlig455_034794 {REF} {Length: 2015} {TRANSSPLICED} {Pfam: CIDE-N domain [PF02017.17, score=38.3]} {RNA1509_27637} {RNA1310_5757} {RNA815_11183}

Mlig455_063165 {REF} {Length: 5571} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=343.2]; Ankyrin repeats (many copies) [PF13637.8, score=282.0]; Ankyrin repeats (many copies) [PF13857.8, score=228.6]; Ankyrin repeat [PF13606.8, score=210.8]; Ankyrin repeat [PF00023.32, score=197.3]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=207, Expect=3e-53]; ENSG00000145362, ANK2, ankyrin 2, [Score=197, Expect=3e-50]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=199, Expect=6e-51]; ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=191, Expect=1e-48]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=202, Expect=3e-52]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=188, Expect=7e-48]} {Smed: dd_Smed_v6_5303_0_2, dd_Smed_v6_5303_0_2, [Score=184, Expect=2e-47]} {RNA1509_27709} {RNA1310_858.1} {RNA815_255.1}
8. MligTC455_41263 96 1.99 Mlig455_009993

Neo: -

Age: -

BCR 0.955 - - - - - 0.955 Mlig455_009993 {REF} {Length: 3188} {Pfam: RhoGAP domain [PF00620.29, score=87.3]} {Human: ENSG00000186716, BCR, BCR, RhoGEF and GTPase activating protein, [Score=84.7, Expect=3e-19]; ENSG00000276016, ABR, ABR, RhoGEF and GTPase activating protein, [Score=82.8, Expect=1e-18]; ENSG00000278741, ABR, ABR, RhoGEF and GTPase activating protein, [Score=82.8, Expect=1e-18]; ENSG00000159842, ABR, ABR, RhoGEF and GTPase activating protein, [Score=82.8, Expect=1e-18]} {Mouse: ENSMUSG00000009681, Bcr, breakpoint cluster region, [Score=85.5, Expect=1e-19]; ENSMUSG00000017631, Abr, active BCR-related gene, [Score=82.8, Expect=9e-19]} {Dmel: FBgn0025836, RhoGAP1A, Rho GTPase activating protein at 1A, [Score=80.9, Expect=3e-18]} {Celegans: WBGene00009800, rrc-1, GTPase-activating protein rrc-1, [Score=73.6, Expect=9e-16]} {Smed: dd_Smed_v6_11121_0_1, dd_Smed_v6_11121_0_1, [Score=74.3, Expect=4e-16]} {RNA1509_36484} {RNA1310_27150.1} {RNA815_24756.1}
9. MligTC455_39323 478 9.96 Mlig455_021384

Neo: -

Age: -

CRELD1 0.954 - - - 0.954 - - Mlig455_021384 {REF} {Length: 3130} {TRANSSPLICED} {Pfam: Calcium-binding EGF domain [PF07645.17, score=33.7]; Complement Clr-like EGF-like [PF12662.9, score=31.8]; TLR4 regulator and MIR-interacting MSAP [PF11938.10, score=31.6]; Laminin EGF domain [PF00053.26, score=19.6]; Human growth factor-like EGF [PF12661.9, score=19.4]} {Human: ENSG00000163703, CRELD1, cysteine rich with EGF like domains 1, [RH, Score=206, Expect=1e-61]; ENSG00000184164, CRELD2, cysteine rich with EGF like domains 2, [RH, Score=199, Expect=1e-59]} {Mouse: ENSMUSG00000030284, Creld1, cysteine-rich with EGF-like domains 1, [RH, Score=208, Expect=2e-62]} {Dmel: FBgn0031217, CG11377, [RH, Score=162, Expect=2e-45]} {Celegans: WBGene00008624, F09E8.2, [RH, Score=166, Expect=3e-47]} {Smed: dd_Smed_v6_4289_0_1, dd_Smed_v6_4289_0_1, [RH, Score=263, Expect=8e-84]} {RNA1509_39062} {RNA1310_10876.1} {RNA815_12990.1}
10. MligTC455_31509 714 14.87 Mlig455_007271, Mlig455_068304

Neo: -

Age: Up-Down-Up

SHOC2 0.95 - - - - - 0.950

Mlig455_007271 {REF} {Length: 5846} {Pfam: Leucine rich repeat [PF13855.8, score=200.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=133.4]; Leucine-rich repeat [PF14580.8, score=33.7]; Leucine Rich Repeat [PF00560.35, score=33.0]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=23.5]} {Human: ENSG00000108061, SHOC2, SHOC2, leucine rich repeat scaffold protein, [Score=412, Expect=1e-135]} {Mouse: ENSMUSG00000024976, Shoc2, Shoc2, leucine rich repeat scaffold protein, [Score=414, Expect=3e-136]} {Dmel: FBgn0038504, Sur-8, [Score=421, Expect=3e-138]} {Celegans: WBGene00004929, soc-2, Leucine-rich repeat protein soc-2, [Score=371, Expect=2e-120]} {Smed: dd_Smed_v6_1909_0_1, dd_Smed_v6_1909_0_1, [Score=384, Expect=5e-125]} {RNA1509_32204} {RNA1310_3548} {RNA815_1725}

Mlig455_068304 {REF} {Length: 4790} {Pfam: Leucine rich repeat [PF13855.8, score=113.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=73.1]; Leucine Rich Repeat [PF00560.35, score=23.8]} {Human: ENSG00000108061, SHOC2, SHOC2, leucine rich repeat scaffold protein, [Score=214, Expect=3e-61]} {Mouse: ENSMUSG00000024976, Shoc2, Shoc2, leucine rich repeat scaffold protein, [Score=216, Expect=6e-62]} {Dmel: FBgn0038504, Sur-8, [Score=231, Expect=2e-67]} {Celegans: WBGene00004929, soc-2, Leucine-rich repeat protein soc-2, [Score=200, Expect=1e-56]} {Smed: dd_Smed_v6_1909_0_1, dd_Smed_v6_1909_0_1, [Score=213, Expect=4e-61]} {RNA1509_27357, RNA1509_32204, RNA1509_7592} {RNA1310_3548, RNA1509_27357, RNA1509_32204, RNA1509_7592} {RNA1509_27357, RNA1509_32204, RNA1509_7592, RNA815_1725}

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