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Results for MligTC455_21323

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_21323 1708 35.59 Mlig455_017330

Neo: -

Age: Down-Up-Up

 RIIAD1 Mlig455_017330 {REF} {Length: 587} {TRANSSPLICED} {Human: ENSG00000178796, RIIAD1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=86.7, Expect=6e-23]} {Mouse: ENSMUSG00000028139, Riiad1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=87.4, Expect=5e-23]} {Smed: dd_Smed_v6_4716_0_2, dd_Smed_v6_4716_0_2, [RH, Score=124, Expect=8e-38]} {RNA1509_4188} {RNA1310_57362} {RNA815_29384.1}

Cumulative graph for MligTC455_21323

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.046 5.299 0.24798 0.89443
RegionR2 0.276 5.299 0.54178 0.90951
RegionR3 0.451 5.299 0.22317 0.76472
RegionR4 0.853 5.299 0.06847 0.23856
RegionR5 0.158 5.299 0.67358 1.00000
RegionR6 0.094 5.299 0.80723 1.00000
RegionR7 -0.316 5.299 0.48095 1.00000
RegionR8 -0.469 5.299 0.37369 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.12 5.299 0.92302 1.00000
RegenerationR2 0.559 5.299 0.19069 0.63457
RegenerationR3 -0.065 5.299 0.88601 1.00000
RegenerationR4 0.178 5.299 0.71162 0.95771
RegenerationR5 -0.517 5.299 0.25732 0.68935
RegenerationR6 -0.751 5.299 0.11961 0.42497
RegenerationBL 0.016 5.299 0.97256 1.00000
RegenerationTP 0.138 5.299 0.78633 1.00000


Genes with expression patterns similar to MligTC455_21323

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_21323 1708 35.59 Mlig455_017330

Neo: -

Age: Down-Up-Up

 RIIAD1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_017330 {REF} {Length: 587} {TRANSSPLICED} {Human: ENSG00000178796, RIIAD1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=86.7, Expect=6e-23]} {Mouse: ENSMUSG00000028139, Riiad1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=87.4, Expect=5e-23]} {Smed: dd_Smed_v6_4716_0_2, dd_Smed_v6_4716_0_2, [RH, Score=124, Expect=8e-38]} {RNA1509_4188} {RNA1310_57362} {RNA815_29384.1}
2. MligTC455_43678 2062 42.95 Mlig455_037165

Neo: -

Age: logFC(26M/2M)=-0.316

 CALM2 4.3 - 0.817 0.736 0.962 0.858 0.927 Mlig455_037165 {REF} {Length: 951} {Pfam: EF-hand domain pair [PF13499.8, score=32.8]; EF hand [PF00036.34, score=28.3]; EF-hand domain [PF14658.8, score=26.2]; EF-hand domain [PF13405.8, score=23.3]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=81.6, Expect=2e-19]; ENSG00000198668, CALM1, calmodulin 1, [Score=81.6, Expect=2e-19]; ENSG00000160014, CALM3, calmodulin 3, [Score=81.6, Expect=2e-19]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=83.2, Expect=3e-20]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=81.6, Expect=1e-19]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=81.6, Expect=1e-19]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=81.6, Expect=1e-19]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=82.4, Expect=5e-20]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.4, Expect=4e-20]} {Smed: dd_Smed_v6_5491_0_1, dd_Smed_v6_5491_0_1, [RH, Score=138, Expect=1e-41]} {RNA1509_38719, RNA1509_7445} {RNA1310_41726.1, RNA1509_38719, RNA1509_7445} {RNA1509_38719, RNA1509_7445, RNA815_20539}
3. MligTC455_37684 4429 92.28 Mlig455_022983

Neo: -

Age: -

 DNALI1 4.276 0.795 0.789 - 0.950 0.865 0.877 Mlig455_022983 {REF} {Length: 1469} {TRANSSPLICED} {Pfam: Axonemal dynein light chain [PF10211.11, score=306.5]; Homeobox associated leucine zipper [PF02183.20, score=19.2]; RIB43A [PF05914.14, score=18.2]} {Human: ENSG00000163879, DNALI1, dynein axonemal light intermediate chain 1, [RH, Score=393, Expect=4e-139]} {Mouse: ENSMUSG00000042707, Dnali1, dynein, axonemal, light intermediate polypeptide 1, [RH, Score=387, Expect=5e-137]} {Dmel: FBgn0037962, CG6971, [RH, Score=283, Expect=3e-96]} {Celegans: WBGene00018307, dyla-1, DYnein Light chain, Axonemal p28 type, [RH, Score=173, Expect=3e-53]} {Smed: dd_Smed_v6_4453_0_1, dd_Smed_v6_4453_0_1, [RH, Score=406, Expect=3e-145]} {RNA1509_10001, RNA1509_17422, RNA1509_28863} {RNA1310_27099, RNA1509_10001, RNA1509_17422, RNA1509_28863} {RNA1509_10001, RNA1509_17422, RNA1509_28863, RNA815_9783}
4. MligTC455_32791 10981 228.76 Mlig455_010839, Mlig455_010869

Neo: -

Age: -

Regeneration-downregulated BL: -1.131

Regeneration-depleted BL: -1.131

 4.167 - 0.752 0.724 0.965 0.909 0.817

Mlig455_010839 {REF} {Length: 1424} {RNA1509_5930} {RNA1310_24478.1} {RNA815_10178}

Mlig455_010869 {REF} {Length: 1422} {RNA1509_10100, RNA1509_16401, RNA1509_35007, RNA1509_44999, RNA1509_50881, RNA1509_5930} {RNA1310_24478.1, RNA1509_10100, RNA1509_16401, RNA1509_35007, RNA1509_44999, RNA1509_50881, RNA1509_5930} {RNA1509_10100, RNA1509_16401, RNA1509_35007, RNA1509_44999, RNA1509_50881, RNA1509_5930, RNA815_10178}
5. MligTC455_22763 1893 39.44 Mlig455_026105

Neo: -

Age: logFC(26M/2M)=-0.375

Region-enriched R2: 1.072/0.04204

 ELOVL4 4.078 - 0.723 0.882 0.952 0.775 0.746 Mlig455_026105 {REF} {Length: 3163} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=218.7]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=322, Expect=4e-110]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=318, Expect=2e-108]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=218, Expect=6e-70]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=80.5, Expect=3e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [RH, Score=358, Expect=3e-125]} {RNA1509_16116, RNA1509_31650, RNA1509_5216} {RNA1310_6579.2, RNA1509_16116, RNA1509_31650, RNA1509_5216} {RNA1509_16116, RNA1509_31650, RNA1509_5216, RNA815_7910}
6. MligTC455_21982 3863 80.47 Mlig455_058064

Neo: -

Age: logFC(26M/2M)=-0.303

 FAM166B 4.05 - 0.750 0.791 0.735 0.798 0.976 Mlig455_058064 {REF} {Length: 4081} {Pfam: Protein of unknown function (DUF2475) [PF10629.11, score=59.5]} {Human: ENSG00000215187, FAM166B, family with sequence similarity 166 member B, [Score=61.2, Expect=7e-10]} {Mouse: ENSMUSG00000042788, Fam166b, family with sequence similarity 166, member B, [Score=58.2, Expect=5e-09]} {Smed: dd_Smed_v6_5010_0_1, dd_Smed_v6_5010_0_1, [Score=204, Expect=6e-62]} {RNA1509_4972} {RNA1310_18908} {RNA815_6281.1}
7. MligTC455_44986 2417 50.36 Mlig455_002882

Neo: -

Age: logFC(26M/2M)=-0.453

 4.049 0.763 - 0.762 0.808 0.958 0.758 Mlig455_002882 {REF} {Length: 1187} {RNA1509_10653, RNA1509_6260} {RNA1310_22176, RNA1509_10653, RNA1509_6260} {RNA1509_10653, RNA1509_6260, RNA815_9068}
8. MligTC455_43627 1683 35.07 Mlig455_012966

Neo: -

Age: -

 3.732 0.967 - - 0.964 0.931 0.870 Mlig455_012966 {REF} {Length: 4640} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=231.1]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=2e-13]} {RNA1509_10570} {RNA1310_7155.1} {RNA815_1910.1}
9. MligTC455_53671 962 20.04 Mlig455_051330

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.598/0.00081

 3.651 0.805 - - 0.972 0.943 0.931 Mlig455_051330 {REF} {Length: 1160} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=53.2]} {RNA1509_56185} {RNA1310_9900, RNA1509_56185} {RNA1509_56185, RNA815_3819.1}
10. MligTC455_29373 3437 71.6 Mlig455_034659

Neo: -

Age: -

 3.498 - 0.780 - 0.965 0.927 0.826 Mlig455_034659 {REF} {Length: 1882} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}
11. MligTC455_40897 1645 34.27 Mlig455_063519

Neo: -

Age: -

 3.498 - - 0.843 0.967 0.907 0.781 Mlig455_063519 {REF} {Length: 1370} {Pfam: Cysteine and tyrosine-rich protein 1 [PF10873.10, score=21.4]} {RNA1509_18073, RNA1509_25726, RNA1509_52666} {RNA1310_31503.1, RNA1509_18073, RNA1509_25726, RNA1509_52666} {RNA1509_18073, RNA1509_25726, RNA1509_52666, RNA815_16246.1}
12. MligTC455_43332 8777 182.85 Mlig455_051763

Neo: -

Age: logFC(26M/2M)=-0.208

 ATP6V1FNB 3.498 - - 0.765 0.879 0.885 0.969 Mlig455_051763 {REF} {Length: 2006} {Human: ENSG00000272899, ATP6V1FNB, ATP6V1F neighbor, [RH, Score=65.9, Expect=5e-13]} {Mouse: ENSMUSG00000109649, Gm45521, predicted gene 45521, [RH, Score=91.3, Expect=1e-22]} {Smed: dd_Smed_v6_3203_0_1, dd_Smed_v6_3203_0_1, [RH, Score=139, Expect=2e-41]} {RNA1509_17359, RNA1509_1918, RNA1509_21014, RNA1509_2512, RNA1509_25978, RNA1509_33873, RNA1509_48877, RNA1509_58524, RNA1509_7632} {RNA1310_18396, RNA1509_17359, RNA1509_1918, RNA1509_21014, RNA1509_2512, RNA1509_25978, RNA1509_33873, RNA1509_48877, RNA1509_58524, RNA1509_7632} {RNA1509_17359, RNA1509_1918, RNA1509_21014, RNA1509_2512, RNA1509_25978, RNA1509_33873, RNA1509_48877, RNA1509_58524, RNA1509_7632, RNA815_7630.1}
13. MligTC455_40089 1886 39.29 Mlig455_065378

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.262

 C9orf135 3.413 - - 0.771 0.962 0.896 0.784 Mlig455_065378 {REF} {Length: 1881} {Pfam: Domain of unknown function (DUF4572) [PF15139.8, score=148.3]} {Human: ENSG00000204711, C9orf135, chromosome 9 open reading frame 135, [RH, Score=106, Expect=8e-26]} {Mouse: ENSMUSG00000033053, 1700028P14Rik, RIKEN cDNA 1700028P14 gene, [RH, Score=85.9, Expect=9e-19]} {Smed: dd_Smed_v6_8797_0_1, dd_Smed_v6_8797_0_1, [RH, Score=123, Expect=7e-33]} {RNA1509_3475, RNA1509_34777} {RNA1310_27695.1, RNA1509_3475, RNA1509_34777} {RNA1509_3475, RNA1509_34777, RNA815_12226}
14. MligTC455_45843 4759 99.14 Mlig455_054096

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.393

 3.373 - 0.808 - 0.962 0.892 0.711 Mlig455_054096 {REF} {Length: 2587} {Smed: dd_Smed_v6_5981_0_1, dd_Smed_v6_5981_0_1, [RH, Score=80.9, Expect=4e-17]} {RNA1509_639} {RNA1310_9589.1, RNA1509_639} {RNA1509_639, RNA815_3156}
15. MligTC455_30289 509 10.61 Mlig455_023807

Neo: -

Age: Up-Down-Down

 DST 3.37 - 0.752 0.865 0.953 - 0.800 Mlig455_023807 {REF} {Length: 10887} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=51.8]; SH3 domain [PF17902.3, score=38.9]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=34.6]; D-amino acid oxidase activator [PF15199.8, score=30.6]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=73.9, Expect=6e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.2, Expect=6e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=85.1, Expect=1e-15]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=51.6, Expect=1e-05]} {Smed: dd_Smed_v6_8220_0_5, dd_Smed_v6_8220_0_5, [Score=163, Expect=9e-40]} {RNA1509_30884, RNA1509_36225, RNA1509_36738, RNA1509_38301, RNA1509_4116, RNA1509_41547, RNA1509_49671, RNA1509_57617, RNA1509_6048} {RNA1310_3340.1, RNA1509_30884, RNA1509_36225, RNA1509_36738, RNA1509_38301, RNA1509_4116, RNA1509_41547, RNA1509_49671, RNA1509_57617, RNA1509_6048} {RNA1509_30884, RNA1509_36225, RNA1509_36738, RNA1509_38301, RNA1509_4116, RNA1509_41547, RNA1509_49671, RNA1509_57617, RNA1509_6048, RNA815_578.1}
16. MligTC455_49237 1147 23.89 Mlig455_053089

Neo: -

Age: Down-Up-Down

 CAMK4 3.345 0.790 - - 0.971 0.874 0.710 Mlig455_053089 {REF} {Length: 2761} {Pfam: Protein kinase domain [PF00069.27, score=263.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.6]; Fungal protein kinase [PF17667.3, score=24.4]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000152495, CAMK4, calcium/calmodulin dependent protein kinase IV, [Score=351, Expect=4e-118]} {Mouse: ENSMUSG00000038128, Camk4, calcium/calmodulin-dependent protein kinase IV, [Score=353, Expect=3e-119]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=248, Expect=2e-79]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=245, Expect=8e-79]} {Smed: dd_Smed_v6_10731_0_1, dd_Smed_v6_10731_0_1, [Score=357, Expect=1e-122]} {RNA1509_27017, RNA1509_8403} {RNA1310_11195.2, RNA1509_27017, RNA1509_8403} {RNA1509_27017, RNA1509_8403, RNA815_9103.1}
17. MligTC455_45408 287 5.98 Mlig455_042398, Mlig455_042478

Neo: -

Age: logFC(26M/2M)=0.529

 TNN 3.327 - - 0.774 0.818 0.957 0.778

Mlig455_042398 {REF} {Length: 1857} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.3]; PAN domain [PF00024.28, score=19.2]} {Human: ENSG00000120332, TNN, tenascin N, [Score=98.6, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=94.7, Expect=7e-22]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=95.9, Expect=2e-21]; ENSMUSG00000026835, Fcnb, ficolin B, [Score=95.5, Expect=2e-22]; ENSMUSG00000026938, Fcna, ficolin A, [Score=95.1, Expect=5e-22]; ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=91.7, Expect=7e-21]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=92.4, Expect=8e-21]} {RNA1509_43257} {RNA1310_625, RNA1509_43257} {RNA1509_43257, RNA815_271}

Mlig455_042478 {REF} {Length: 1926} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=124.2]} {Human: ENSG00000120332, TNN, tenascin N, [Score=98.2, Expect=3e-22]; ENSG00000160339, FCN2, ficolin 2, [Score=94.7, Expect=7e-22]} {Mouse: ENSMUSG00000026835, Fcnb, ficolin B, [Score=95.5, Expect=2e-22]; ENSMUSG00000026725, Tnn, tenascin N, [Score=95.5, Expect=2e-21]; ENSMUSG00000026938, Fcna, ficolin A, [Score=95.1, Expect=4e-22]; ENSMUSG00000028989, Angptl7, angiopoietin-like 7, [Score=92.0, Expect=7e-21]} {Dmel: FBgn0050280, CG30280, [Score=97.8, Expect=1e-23]} {Celegans: WBGene00020516, T15B7.1, [Score=65.9, Expect=6e-12]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=92.0, Expect=9e-21]} {RNA1509_43257} {RNA1310_625} {RNA815_271}
18. MligTC455_53630 6522 135.87 Mlig455_064704

Neo: -

Age: Down-Down-Up

 DNAL1 3.322 - - 0.749 0.951 0.866 0.756 Mlig455_064704 {REF} {Length: 942} {TRANSSPLICED} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=51.8]; Leucine-rich repeat [PF14580.8, score=37.7]; Leucine rich repeat [PF13855.8, score=31.9]} {Human: ENSG00000119661, DNAL1, dynein axonemal light chain 1, [RH, Score=298, Expect=6e-104]} {Mouse: ENSMUSG00000042523, Dnal1, dynein, axonemal, light chain 1, [RH, Score=300, Expect=6e-105]} {Dmel: FBgn0033408, CG8800, [RH, Score=212, Expect=2e-70]} {Celegans: WBGene00015516, C06A8.6, [Score=62.8, Expect=8e-12]} {Smed: dd_Smed_v6_6302_0_1, dd_Smed_v6_6302_0_1, [RH, Score=285, Expect=1e-99]} {RNA1509_18941, RNA1509_2404, RNA1509_46381, RNA1509_53800} {RNA1310_37933.1, RNA1509_18941, RNA1509_2404, RNA1509_46381, RNA1509_53800} {RNA1509_18941, RNA1509_2404, RNA1509_46381, RNA1509_53800, RNA815_17921}
19. MligTC455_45837 631 13.15 Mlig455_055002

Neo: -

Age: -

 3.311 - - 0.818 0.957 0.822 0.714 Mlig455_055002 {REF} {Length: 821} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
20. MligTC455_48123 1826 38.05 Mlig455_039614

Neo: -

Age: -

 3.286 - 0.702 0.843 0.955 - 0.786 Mlig455_039614 {REF} {Length: 4721} {Smed: dd_Smed_v6_7960_0_1, dd_Smed_v6_7960_0_1, [RH, Score=94.4, Expect=1e-24]} {RNA1509_46977} {RNA1310_32988} {RNA815_14341}
21. MligTC455_10416 765 15.93 Mlig455_008958

Neo: -

Age: -

Region-enriched R8: 1.474/0.04842

 3.239 0.963 - 0.710 0.737 0.829 - Mlig455_008958 {REF} {Length: 515} {NoTransDecoderORF} {RNA1310_120997} {RNA815_53530}
22. MligTC455_43157 3287 68.49 Mlig455_013587

Neo: -

Age: logFC(26M/2M)=0.344

Regeneration-upregulated BL: 1.543

Regeneration-enriched BL: 1.543

 3.137 0.950 0.772 0.710 - 0.705 - Mlig455_013587 {REF} {Length: 1959} {Pfam: Cupin-like domain [PF13621.8, score=40.0]} {Dmel: FBgn0038510, CG14331, [RH, Score=218, Expect=9e-69]} {Smed: dd_Smed_v6_8235_0_1, dd_Smed_v6_8235_0_1, [Score=190, Expect=2e-57]} {RNA1509_25780, RNA1509_9888} {RNA1310_15437, RNA1509_25780} {RNA1509_25780, RNA815_7588}
23. MligTC455_43615 1202 25.04 Mlig455_024404

Neo: -

Age: logFC(26M/2M)=-0.268

 CFAP57 2.756 - - - 0.955 0.898 0.903 Mlig455_024404 {REF} {Length: 5259} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=66.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=23.3]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=19.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=494, Expect=2e-154]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1619, Expect=0.0]} {RNA1509_18223, RNA1509_836} {RNA1310_1737, RNA1509_18223, RNA1509_836} {RNA1509_18223, RNA1509_836, RNA815_558}
24. MligTC455_44157 2728 56.84 Mlig455_015483

Neo: -

Age: logFC(26M/2M)=-0.621

Region-enriched R4: 1.377/0.00397

 SPAG8 2.745 - - 0.900 0.963 0.882 - Mlig455_015483 {REF} {Length: 1025} {Human: ENSG00000137098, SPAG8, sperm associated antigen 8, [RH, Score=83.2, Expect=3e-18]} {Mouse: ENSMUSG00000066196, Spag8, sperm associated antigen 8, [RH, Score=90.9, Expect=4e-21]} {Smed: dd_Smed_v6_6123_0_1, dd_Smed_v6_6123_0_1, [RH, Score=131, Expect=1e-38]} {RNA1509_3548} {RNA1310_4106} {RNA815_16577}
25. MligTC455_44022 2840 59.17 Mlig455_027438

Neo: -

Age: Down-Down-Down

 STYXL1 2.74 - - 0.951 0.910 0.879 - Mlig455_027438 {REF} {Length: 1257} {Pfam: Dual specificity phosphatase, catalytic domain [PF00782.22, score=65.4]; Rhodanese-like domain [PF00581.22, score=29.2]} {Human: ENSG00000127952, STYXL1, serine/threonine/tyrosine interacting like 1, [RH, Score=196, Expect=9e-61]} {Mouse: ENSMUSG00000019178, Styxl1, serine/threonine/tyrosine interacting-like 1, [RH, Score=187, Expect=2e-57]} {Dmel: FBgn0039742, CG15528, [Score=52.8, Expect=6e-08]} {Celegans: WBGene00017428, F13D11.3, [Score=55.8, Expect=2e-09]} {Smed: dd_Smed_v6_11358_0_1, dd_Smed_v6_11358_0_1, [RH, Score=251, Expect=7e-83]} {RNA1509_4392} {RNA1310_10767.2} {RNA815_8325.1}
26. MligTC455_44156 2600 54.17 Mlig455_003573

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.373/0.00496

 SPAG8 2.703 - - 0.905 0.970 0.828 - Mlig455_003573 {REF} {Length: 1006} {Human: ENSG00000137098, SPAG8, sperm associated antigen 8, [RH, Score=81.6, Expect=8e-18]} {Mouse: ENSMUSG00000066196, Spag8, sperm associated antigen 8, [RH, Score=89.4, Expect=1e-20]} {Smed: dd_Smed_v6_6123_0_1, dd_Smed_v6_6123_0_1, [RH, Score=130, Expect=3e-38]} {RNA1509_11454, RNA1509_3548} {RNA1310_4106, RNA1509_11454} {RNA1509_11454, RNA815_16577}
27. MligTC455_52993 2784 58.01 Mlig455_026924

Neo: -

Age: -

Region-enriched R4: 1.003/0.00472

 2.68 - - 0.804 0.964 0.912 - Mlig455_026924 {REF} {Length: 827} {TRANSSPLICED} {Smed: dd_Smed_v6_8079_0_1, dd_Smed_v6_8079_0_1, [RH, Score=190, Expect=1e-62]} {RNA1509_10405} {RNA1310_42303.1} {RNA815_21489}
28. MligTC455_44144 1917 39.94 Mlig455_013403

Neo: -

Age: logFC(26M/2M)=-0.387

 TNKS 2.674 - - 0.791 0.953 0.930 - Mlig455_013403 {REF} {Length: 3109} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=73.2]; Ankyrin repeats (many copies) [PF13857.8, score=57.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.5]; Ion transport protein [PF00520.33, score=51.4]; Ankyrin repeat [PF00023.32, score=50.9]; Ankyrin repeat [PF13606.8, score=46.3]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=88.6, Expect=3e-17]; ENSG00000285372, AC270292.3, tankyrase, [Score=87.4, Expect=7e-17]; ENSG00000107854, TNKS2, tankyrase 2, [Score=84.3, Expect=6e-16]} {Mouse: ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=87.4, Expect=4e-17]; ENSMUSG00000024811, Tnks2, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, [Score=84.0, Expect=5e-16]} {Dmel: FBgn0004647, N, Notch, [Score=80.1, Expect=7e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=82.8, Expect=6e-16]} {Smed: dd_Smed_v6_8547_0_1, dd_Smed_v6_8547_0_1, [Score=79.3, Expect=6e-15]} {RNA1509_2994} {RNA1310_1688.1, RNA1509_2994} {RNA1509_2994, RNA815_1415.1}
29. MligTC455_51339 75 1.56 Mlig455_024282

Neo: -

Age: -

 2.669 0.913 - - 0.801 0.955 - Mlig455_024282 {REF} {Length: 2404} {RNA1310_48051} {RNA815_14784}
30. MligTC455_16370 2203 45.9 Mlig455_030628, Mlig455_031013

Neo: -

Age: logFC(26M/2M)=-0.323

 ARMC3 2.646 - - 0.927 0.977 0.742 -

Mlig455_030628 {REF} {Length: 2931} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.4]; Armadillo/beta-catenin-like repeat [PF00514.25, score=81.7]; HEAT repeats [PF13646.8, score=63.8]; HEAT-like repeat [PF13513.8, score=49.3]; V-ATPase subunit H [PF11698.10, score=49.2]; HEAT repeat [PF02985.24, score=38.5]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=29.0]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=496, Expect=2e-162]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=471, Expect=7e-153]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=665, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}

Mlig455_031013 {REF} {Length: 2952} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.8]; Armadillo/beta-catenin-like repeat [PF00514.25, score=80.8]; HEAT repeats [PF13646.8, score=63.8]; V-ATPase subunit H [PF11698.10, score=50.9]; HEAT-like repeat [PF13513.8, score=48.4]; HEAT repeat [PF02985.24, score=40.7]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=31.6]; Required for nuclear transport of RNA pol II C-terminus 1 [PF10363.11, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=474, Expect=3e-154]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=335, Expect=1e-101]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=643, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}
31. MligTC455_37386 1075 22.39 Mlig455_004178, Mlig455_041121, Mlig455_041175

Neo: -

Age: Down-Up-Up

 TRHR 2.62 - - 0.781 0.959 0.880 -

Mlig455_004178 {REF} {Length: 1426} {Smed: dd_Smed_v6_16261_0_1, dd_Smed_v6_16261_0_1, [Score=55.1, Expect=2e-09]} {RNA1509_14001} {RNA1310_23895.2, RNA1509_14001} {RNA1509_14001, RNA815_14474.1}

Mlig455_041121 {REF} {Length: 2021} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=52.2]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=46.0]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.9]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=64.7, Expect=1e-10]} {Mouse: ENSMUSG00000026237, Nmur1, neuromedin U receptor 1, [Score=68.6, Expect=4e-12]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=64.3, Expect=8e-11]} {Celegans: WBGene00011765, frpr-17, FMRFamide Peptide Receptor family, [RH, Score=79.3, Expect=6e-16]} {Smed: dd_Smed_v6_37609_0_1, dd_Smed_v6_37609_0_1, [Score=145, Expect=5e-40]}

Mlig455_041175 {REF} {Length: 1447} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=52.0]; Serpentine type 7TM GPCR chemoreceptor Srw [PF10324.11, score=45.8]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.3]} {Human: ENSG00000174417, TRHR, thyrotropin releasing hormone receptor, [Score=64.3, Expect=2e-10]} {Mouse: ENSMUSG00000026237, Nmur1, neuromedin U receptor 1, [Score=68.6, Expect=5e-12]} {Dmel: FBgn0053696, CNMaR, CNMamide Receptor, [Score=63.9, Expect=1e-10]} {Celegans: WBGene00011765, frpr-17, FMRFamide Peptide Receptor family, [RH, Score=79.3, Expect=6e-16]} {Smed: dd_Smed_v6_37609_0_1, dd_Smed_v6_37609_0_1, [Score=145, Expect=9e-40]}
32. MligTC455_33599 990 20.63 Mlig455_059026

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.377

 CPLANE1 2.619 - 0.766 - 0.952 0.901 - Mlig455_059026 {REF} {Length: 10323} {TRANSSPLICED} {Pfam: Joubert syndrome-associated [PF15392.8, score=19.1]} {Human: ENSG00000197603, CPLANE1, ciliogenesis and planar polarity effector 1, [RH, Score=136, Expect=6e-31]} {Mouse: ENSMUSG00000039801, Cplane1, ciliogenesis and planar polarity effector 1, [RH, Score=138, Expect=1e-31]} {RNA1509_1312, RNA1509_13367, RNA1509_16834, RNA1509_24724} {RNA1310_343.1, RNA1509_1312, RNA1509_13367, RNA1509_16834, RNA1509_24724} {RNA1509_1312, RNA1509_13367, RNA1509_16834, RNA1509_24724, RNA815_482.1}
33. MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

 2.618 - 0.792 - - 0.957 0.869

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}
34. MligTC455_49067 1176 24.5 Mlig455_040676, Mlig455_064541

Neo: -

Age: logFC(26M/2M)=-0.241

 2.618 - - 0.748 0.920 - 0.950

Mlig455_040676 {REF} {Length: 3487} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=33.3]} {RNA1509_5459} {RNA1310_5182} {RNA815_5673}

Mlig455_064541 {REF} {Length: 3584} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=30.4]} {RNA1509_5459} {RNA1310_5182, RNA1509_5459} {RNA1509_5459, RNA815_5673}
35. MligTC455_44042 460 9.59 Mlig455_021815

Neo: -

Age: logFC(26M/2M)=-0.341

 CCDC181 2.617 - - 0.750 0.952 0.915 - Mlig455_021815 {REF} {Length: 2436} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4207) [PF13904.8, score=29.1]} {Human: ENSG00000117477, CCDC181, coiled-coil domain containing 181, [Score=70.5, Expect=2e-12]} {Mouse: ENSMUSG00000026578, Ccdc181, coiled-coil domain containing 181, [Score=72.0, Expect=4e-13]} {Smed: dd_Smed_v6_8117_0_1, dd_Smed_v6_8117_0_1, [Score=76.6, Expect=6e-15]} {RNA1509_20789} {RNA1310_10957.1, RNA1509_20789} {RNA1509_20789, RNA815_9557}
36. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

 GRIA2 2.61 - - - 0.926 0.956 0.728

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
37. MligTC455_36729 109 2.26 Mlig455_031568

Neo: -

Age: -

Region-enriched R2: 4.085/0.04774

 2.604 - - 0.793 0.861 0.950 - Mlig455_031568 {REF} {Length: 4709} {RNA1310_20703.1} {RNA815_12377}
38. MligTC455_29557 797 16.6 Mlig455_040172

Neo: -

Age: logFC(26M/2M)=-0.290

 TMEM67 2.594 0.950 0.831 - - 0.813 - Mlig455_040172 {REF} {Length: 3157} {Pfam: Meckelin (Transmembrane protein 67) [PF09773.11, score=669.0]} {Human: ENSG00000164953, TMEM67, transmembrane protein 67, [Score=437, Expect=1e-140]} {Mouse: ENSMUSG00000049488, Tmem67, transmembrane protein 67, [Score=429, Expect=1e-136]} {Dmel: FBgn0038814, CG15923, [Score=139, Expect=9e-34]} {Celegans: WBGene00018042, mks-3, MecKel-Gruber Syndrome (MKS) homolog, [Score=278, Expect=2e-81]} {Smed: dd_Smed_v6_7765_0_1, dd_Smed_v6_7765_0_1, [Score=476, Expect=9e-156]} {RNA1509_26795, RNA1509_3205, RNA1509_40554} {RNA1310_2827.1, RNA1509_26795, RNA1509_40554} {RNA1509_26795, RNA1509_40554, RNA815_833}
39. MligTC455_48124 3676 76.59 Mlig455_051417, Mlig455_051432

Neo: -

Age: Down-Up-Up

 2.587 - - 0.844 0.961 - 0.782

Mlig455_051417 {REF} {Length: 3031} {Smed: dd_Smed_v6_7960_0_1, dd_Smed_v6_7960_0_1, [RH, Score=95.1, Expect=7e-25]} {RNA1509_46977} {RNA1310_32988} {RNA815_14341}

Mlig455_051432 {REF} {Length: 2527} {Smed: dd_Smed_v6_7960_0_1, dd_Smed_v6_7960_0_1, [RH, Score=95.1, Expect=7e-25]} {RNA1509_20098, RNA1509_21397, RNA1509_37175, RNA1509_42608, RNA1509_46977, RNA1509_47629} {RNA1310_32988, RNA1509_20098, RNA1509_21397, RNA1509_37175, RNA1509_42608, RNA1509_46977, RNA1509_47629} {RNA1509_20098, RNA1509_21397, RNA1509_37175, RNA1509_42608, RNA1509_46977, RNA1509_47629, RNA815_14341}
40. MligTC455_17318 828 17.24 Mlig455_016719

Neo: -

Age: -

Region-enriched R2: 1.905/0.03396

 NOXRED1 2.582 - - 0.757 0.950 0.875 - Mlig455_016719 {REF} {Length: 1953} {Pfam: NADP oxidoreductase coenzyme F420-dependent [PF03807.19, score=37.8]} {Human: ENSG00000165555, NOXRED1, NADP dependent oxidoreductase domain containing 1, [RH, Score=130, Expect=8e-33]} {Mouse: ENSMUSG00000072919, Noxred1, NADP+ dependent oxidoreductase domain containing 1, [RH, Score=128, Expect=4e-32]} {Smed: dd_Smed_v6_14962_0_1, dd_Smed_v6_14962_0_1, [Score=133, Expect=2e-34]} {RNA1509_13348} {RNA1310_24844} {RNA815_21464}
41. MligTC455_26606 1197 24.94 Mlig455_035969

Neo: -

Age: -

 2.574 - - - 0.951 0.882 0.741 Mlig455_035969 {REF} {Length: 1942} {RNA1509_10606, RNA1509_25602} {RNA1310_13915, RNA1509_10606, RNA1509_25602} {RNA1509_10606, RNA1509_25602, RNA815_6086}
42. MligTC455_22198 766 15.95 Mlig455_054315

Neo: -

Age: -

 DCDC1 2.565 - - 0.823 0.972 - 0.770 Mlig455_054315 {REF} {Length: 7168} {Pfam: Cep120 protein [PF12416.10, score=49.6]; Doublecortin [PF03607.19, score=39.3]; KHA, dimerisation domain of potassium ion channel [PF11834.10, score=22.6]; CIDE-N domain [PF02017.17, score=21.0]} {Human: ENSG00000170959, DCDC1, doublecortin domain containing 1, [RH, Score=399, Expect=1e-112]} {Smed: dd_Smed_v6_11770_0_1, dd_Smed_v6_11770_0_1, [RH, Score=297, Expect=6e-81]} {RNA1509_1192} {RNA1310_347} {RNA815_115}
43. MligTC455_21322 2058 42.87 Mlig455_017252

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.359

 RIIAD1 2.561 - - 0.772 0.967 - 0.822 Mlig455_017252 {REF} {Length: 599} {TRANSSPLICED} {Human: ENSG00000178796, RIIAD1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=86.7, Expect=6e-23]} {Mouse: ENSMUSG00000028139, Riiad1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=87.4, Expect=5e-23]} {Smed: dd_Smed_v6_4716_0_2, dd_Smed_v6_4716_0_2, [RH, Score=124, Expect=8e-38]} {RNA1509_4188} {RNA1310_57362, RNA1509_4188} {RNA1509_4188, RNA815_29384.1}
44. MligTC455_27638 969 20.19 Mlig455_022789

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.917

 CLUAP1 2.558 - - 0.718 - 0.956 0.884 Mlig455_022789 {REF} {Length: 2458} {Pfam: Clusterin-associated protein-1 [PF10234.11, score=358.0]} {Human: ENSG00000103351, CLUAP1, clusterin associated protein 1, [RH, Score=332, Expect=1e-110]} {Mouse: ENSMUSG00000014232, Cluap1, clusterin associated protein 1, [RH, Score=330, Expect=8e-110]} {Dmel: FBgn0031196, CG17599, [RH, Score=135, Expect=1e-34]} {Celegans: WBGene00001119, dyf-3, Clusterin-associated protein 1 homolog, [RH, Score=215, Expect=1e-65]} {Smed: dd_Smed_v6_8287_0_1, dd_Smed_v6_8287_0_1, [RH, Score=333, Expect=2e-110]} {RNA1509_14292, RNA1509_25335} {RNA1310_15979, RNA1509_14292, RNA1509_25335} {RNA1509_14292, RNA1509_25335, RNA815_6417.1}
45. MligTC455_22197 774 16.13 Mlig455_003800

Neo: -

Age: -

 DCDC1 2.542 - - 0.829 0.966 - 0.747 Mlig455_003800 {REF} {Length: 7175} {Pfam: Doublecortin [PF03607.19, score=36.2]; KHA, dimerisation domain of potassium ion channel [PF11834.10, score=20.0]} {Human: ENSG00000170959, DCDC1, doublecortin domain containing 1, [Score=248, Expect=7e-66]} {Smed: dd_Smed_v6_11770_0_1, dd_Smed_v6_11770_0_1, [Score=213, Expect=2e-55]} {RNA1509_1192} {RNA1310_347} {RNA815_115}
46. MligTC455_16540 670 13.96 Mlig455_047920

Neo: -

Age: logFC(26M/2M)=-0.281

 2.537 - - 0.840 0.956 - 0.741 Mlig455_047920 {REF} {Length: 1171} {RNA1509_47877} {RNA1310_33926.1, RNA1509_47877} {RNA1509_47877, RNA815_27874}
47. MligTC455_03539 348 7.26 Mlig455_008698

Neo: -

Age: -

 2.528 - - 0.763 0.812 0.953 - Mlig455_008698 {REF} {Length: 854} {NoTransDecoderORF} {RNA1509_55686} {RNA1310_45961, RNA1509_55686} {RNA1509_55686, RNA815_23040}
48. MligTC455_54077 937 19.53 Mlig455_032159, Mlig455_032165

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.640

 TLL2 2.523 - - 0.801 0.766 0.956 -

Mlig455_032159 {REF} {Length: 1358} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}

Mlig455_032165 {REF} {Length: 1696} {Pfam: CUB domain [PF00431.22, score=63.7]} {Human: ENSG00000095587, TLL2, tolloid like 2, [Score=62.8, Expect=4e-10]; ENSG00000107611, CUBN, cubilin, [Score=62.0, Expect=1e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=61.2, Expect=1e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=68.9, Expect=4e-12]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}
49. MligTC455_49579 654 13.62 Mlig455_042523

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.646

Region-enriched R2: 1.286/0.04858

 ANO7 2.52 - - 0.814 0.960 - 0.746 Mlig455_042523 {REF} {Length: 4425} {Pfam: Calcium-activated chloride channel [PF04547.14, score=254.3]; Dimerisation domain of Ca+-activated chloride-channel, anoctamin [PF16178.7, score=23.0]} {Human: ENSG00000146205, ANO7, anoctamin 7, [Score=118, Expect=3e-26]} {Mouse: ENSMUSG00000034107, Ano7, anoctamin 7, [Score=124, Expect=4e-28]} {Dmel: FBgn0030349, CG10353, [Score=119, Expect=7e-27]} {Celegans: WBGene00010138, anoh-1, Anoctamin, [Score=161, Expect=4e-40]} {Smed: dd_Smed_v6_6514_0_4, dd_Smed_v6_6514_0_4, [Score=127, Expect=2e-29]} {RNA1509_21269} {RNA1310_4099.1} {RNA815_1067}
50. MligTC455_41580 574 11.95 Mlig455_001194

Neo: -

Age: -

 RBPMS 2.519 - - 0.825 0.741 0.953 - Mlig455_001194 {REF} {Length: 2007} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=63.4]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=23.1]} {Human: ENSG00000157110, RBPMS, RNA binding protein, mRNA processing factor, [RH, Score=135, Expect=2e-38]; ENSG00000166831, RBPMS2, RNA binding protein, mRNA processing factor 2, [RH, Score=134, Expect=1e-37]} {Mouse: ENSMUSG00000032387, Rbpms2, RNA binding protein with multiple splicing 2, [RH, Score=138, Expect=2e-39]; ENSMUSG00000031586, Rbpms, RNA binding protein gene with multiple splicing, [RH, Score=133, Expect=1e-37]} {Dmel: FBgn0263995, cpo, couch potato, [RH, Score=203, Expect=1e-59]} {Celegans: WBGene00003172, mec-8, Mec-8 protein, [RH, Score=144, Expect=5e-41]} {Smed: dd_Smed_v6_4296_0_3, dd_Smed_v6_4296_0_3, [RH, Score=161, Expect=2e-47]} {RNA1509_12950} {RNA1310_3819.2} {RNA815_19117.1}
51. MligTC455_33364 348 7.24 Mlig455_009410, Mlig455_016109, Mlig455_026502, Mlig455_027903, Mlig455_036913, Mlig455_066713, Mlig455_068644, Mlig455_070501

Neo: -

Age: logFC(26M/2M)=-0.641

 NYNRIN 2.509 - - 0.746 0.802 0.961 -

Mlig455_009410 {REF} {Length: 6826} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=304.8]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=92.4, Expect=4e-20]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=209, Expect=1e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=301, Expect=1e-97]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_016109 {REF} {Length: 3482} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.5]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.8]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=55.7]; Aspartyl protease [PF13650.8, score=21.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=7e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=124, Expect=4e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=425, Expect=7e-131]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}

Mlig455_026502 {REF} {Length: 698} {Pfam: Zinc knuckle [PF00098.25, score=27.8]} {RNA1509_38652} {RNA1310_25149.1} {RNA815_13280}

Mlig455_027903 {REF} {Length: 3748} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.7]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=51.2]; Aspartyl protease [PF13650.8, score=21.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=121, Expect=5e-27]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=122, Expect=1e-27]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=432, Expect=8e-134]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_036913 {REF} {Length: 639} {RNA1509_48973} {RNA1310_39833} {RNA815_36286}

Mlig455_066713 {REF} {Length: 2873} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=122.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.1]; Integrase zinc binding domain [PF17921.3, score=77.1]; Integrase core domain [PF00665.28, score=53.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=117, Expect=3e-26]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=117, Expect=4e-26]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=237, Expect=1e-65]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_068644 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.2]; Integrase zinc binding domain [PF17921.3, score=79.7]; Integrase core domain [PF00665.28, score=49.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=130, Expect=4e-30]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=6e-29]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=313, Expect=5e-93]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_070501 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=123.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.2]; Integrase zinc binding domain [PF17921.3, score=76.5]; Integrase core domain [PF00665.28, score=54.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=2e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=1e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=322, Expect=2e-96]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}
52. MligTC455_42102 930 19.38 Mlig455_045887

Neo: -

Age: logFC(26M/2M)=-0.310

 CASP7 2.503 0.727 - - 0.957 0.819 - Mlig455_045887 {REF} {Length: 2351} {Pfam: Caspase domain [PF00656.24, score=70.4]; Lecithin retinol acyltransferase [PF04970.15, score=43.8]} {Human: ENSG00000165806, CASP7, caspase 7, [Score=99.0, Expect=2e-22]; ENSG00000164305, CASP3, caspase 3, [Score=98.6, Expect=2e-22]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=100, Expect=6e-23]; ENSMUSG00000031628, Casp3, caspase 3, [Score=99.0, Expect=1e-22]} {Dmel: FBgn0019972, Drice, Death related ICE-like caspase, [Score=78.2, Expect=2e-15]} {Smed: dd_Smed_v6_1167_0_1, dd_Smed_v6_1167_0_1, [Score=98.2, Expect=5e-23]} {RNA1509_54325, RNA1509_54631} {RNA1310_1479.1, RNA1509_54325, RNA1509_54631} {RNA1509_54325, RNA1509_54631, RNA815_4880}
53. MligTC455_40802 690 14.37 Mlig455_058344

Neo: -

Age: -

 2.488 - - 0.805 0.714 - 0.969 Mlig455_058344 {REF} {Length: 1602} {RNA1509_24787} {RNA1310_5189, RNA1509_24787} {RNA1509_24787, RNA815_3770}
54. MligTC455_44850 2381 49.6 Mlig455_014259

Neo: -

Age: logFC(26M/2M)=-0.355

 LEXM 2.452 - 0.748 - 0.739 0.965 - Mlig455_014259 {REF} {Length: 2739} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1, RNA1509_2011} {RNA1509_2011, RNA815_5377}
55. MligTC455_37826 1175 24.49 Mlig455_028001

Neo: -

Age: -

Region-enriched R4: 1.191/0.00974

 MORN5 2.416 - 0.728 - 0.954 - 0.734 Mlig455_028001 {REF} {Length: 1988} {Pfam: MORN repeat [PF02493.22, score=58.1]} {Human: ENSG00000185681, MORN5, MORN repeat containing 5, [RH, Score=239, Expect=2e-81]} {Mouse: ENSMUSG00000026894, Morn5, MORN repeat containing 5, [RH, Score=229, Expect=2e-77]} {Dmel: FBgn0036016, CG3306, [RH, Score=55.8, Expect=2e-09]} {Smed: dd_Smed_v6_7020_0_1, dd_Smed_v6_7020_0_1, [RH, Score=263, Expect=3e-91]} {RNA1509_32878} {RNA1310_34507.1} {RNA815_10362}
56. MligTC455_17049 6274 130.71 Mlig455_029792, Mlig455_029942

Neo: -

Age: logFC(26M/2M)=-0.392

 EFCAB2 1.881 0.953 - - 0.928 - -

Mlig455_029792 {REF} {Length: 935} {Pfam: EF-hand domain pair [PF13499.8, score=44.0]; EF-hand domain [PF13405.8, score=39.7]; EF hand [PF00036.34, score=28.8]; EF-hand domain [PF14658.8, score=24.5]} {Human: ENSG00000203666, EFCAB2, EF-hand calcium binding domain 2, [RH, Score=204, Expect=8e-67]} {Mouse: ENSMUSG00000026495, Efcab2, EF-hand calcium binding domain 2, [RH, Score=209, Expect=9e-70]} {Dmel: FBgn0034481, CG11041, [RH, Score=139, Expect=1e-42]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.0, Expect=3e-20]} {Smed: dd_Smed_v6_11976_0_1, dd_Smed_v6_11976_0_1, [RH, Score=192, Expect=1e-63]} {RNA1509_6027, RNA1509_9780} {RNA1310_41624, RNA1509_6027, RNA1509_9780} {RNA1509_6027, RNA1509_9780, RNA815_18008}

Mlig455_029942 {REF} {Length: 933} {Pfam: EF-hand domain pair [PF13499.8, score=44.0]; EF-hand domain [PF13405.8, score=39.7]; EF hand [PF00036.34, score=28.8]; EF-hand domain [PF14658.8, score=24.5]} {Human: ENSG00000203666, EFCAB2, EF-hand calcium binding domain 2, [RH, Score=204, Expect=8e-67]} {Mouse: ENSMUSG00000026495, Efcab2, EF-hand calcium binding domain 2, [RH, Score=209, Expect=9e-70]} {Dmel: FBgn0034481, CG11041, [RH, Score=139, Expect=1e-42]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.0, Expect=3e-20]} {Smed: dd_Smed_v6_11976_0_1, dd_Smed_v6_11976_0_1, [RH, Score=192, Expect=1e-63]} {RNA1509_6027} {RNA1310_41624} {RNA815_18008}
57. MligTC455_24073 886 18.47 Mlig455_022269

Neo: -

Age: logFC(26M/2M)=-0.424

 1.837 - - 0.887 0.950 - - Mlig455_022269 {REF} {Length: 2445} {Smed: dd_Smed_v6_8763_0_1, dd_Smed_v6_8763_0_1, [RH, Score=98.6, Expect=8e-23]} {RNA1509_5814} {RNA1310_13945} {RNA815_5072}
58. MligTC455_49635 2917 60.78 Mlig455_021335

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.377

 LRTOMT 1.83 - - - - 0.880 0.950 Mlig455_021335 {REF} {Length: 944} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=44.2]; Leucine-rich repeat [PF14580.8, score=43.9]; Leucine rich repeat [PF13855.8, score=36.8]} {Human: ENSG00000184154, LRTOMT, leucine rich transmembrane and O-methyltransferase domain containing, [RH, Score=145, Expect=4e-43]} {Mouse: ENSMUSG00000064307, Lrrc51, leucine rich repeat containing 51, [RH, Score=149, Expect=6e-45]} {Celegans: WBGene00003390, mog-2, Probable U2 small nuclear ribonucleoprotein A', [Score=59.3, Expect=2e-10]} {Smed: dd_Smed_v6_8583_0_1, dd_Smed_v6_8583_0_1, [RH, Score=170, Expect=4e-53]} {RNA1509_7051} {RNA1310_42278, RNA1509_7051} {RNA1509_7051, RNA815_19576}
59. MligTC455_35567 1282 26.72 Mlig455_021647

Neo: -

Age: -

 CFAP44 1.829 - - - 0.963 0.866 - Mlig455_021647 {REF} {Length: 728} {Human: ENSG00000206530, CFAP44, cilia and flagella associated protein 44, [Score=56.2, Expect=5e-10]} {Smed: dd_Smed_v6_8760_0_1, dd_Smed_v6_8760_0_1, [Score=67.4, Expect=2e-14]} {RNA1509_43550} {RNA1310_10626} {RNA815_87.1}
60. MligTC455_16724 211 4.4 Mlig455_055966

Neo: -

Age: Up-Down-Up

 PTEN 1.824 - - - 0.874 0.950 - Mlig455_055966 {REF} {Length: 4096} {TRANSSPLICED} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=72.2]} {Human: ENSG00000284792, PTEN, phosphatase and tensin homolog, [Score=265, Expect=1e-81]; ENSG00000171862, PTEN, phosphatase and tensin homolog, [Score=262, Expect=9e-83]} {Mouse: ENSMUSG00000013663, Pten, phosphatase and tensin homolog, [Score=262, Expect=6e-83]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=214, Expect=3e-64]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=147, Expect=1e-37]} {Smed: dd_Smed_v6_7478_0_1, dd_Smed_v6_7478_0_1, [RH, Score=225, Expect=6e-69]} {RNA1509_17397} {RNA1310_7531.2} {RNA815_4064}
61. MligTC455_40846 835 17.39 Mlig455_030827, Mlig455_047790

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

 KCNMA1 1.802 - - - 0.844 0.958 -

Mlig455_030827 {REF} {Length: 3985} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=88.0]; Ion channel [PF07885.18, score=46.9]; Ion transport protein [PF00520.33, score=25.2]; TrkA-N domain [PF02254.20, score=24.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=482, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=481, Expect=3e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=339, Expect=4e-99]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=459, Expect=8e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=479, Expect=1e-151]} {RNA1509_12064, RNA1509_38332} {RNA1310_2763, RNA1509_38332} {RNA1509_38332, RNA815_792.1}

Mlig455_047790 {REF} {Length: 4417} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=87.7]; Ion channel [PF07885.18, score=46.7]; TrkA-N domain [PF02254.20, score=23.6]; Ion transport protein [PF00520.33, score=21.9]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=479, Expect=1e-148]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=478, Expect=7e-149]} {Dmel: FBgn0003429, slo, slowpoke, [Score=340, Expect=2e-98]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=455, Expect=1e-140]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=475, Expect=3e-148]} {RNA1509_38332, RNA1509_48456} {RNA1310_2763, RNA1509_48456} {RNA1509_48456, RNA815_792.1}
62. MligTC455_43696 444 9.25 Mlig455_002424

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.324

 MARK2 1.794 0.830 - - 0.964 - - Mlig455_002424 {REF} {Length: 4150} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=258.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=155.9]; Kinase associated domain 1 [PF02149.21, score=68.1]; Kinase-like [PF14531.8, score=33.8]; ABC1 atypical kinase-like domain [PF03109.18, score=25.3]; RIO1 family [PF01163.24, score=19.2]} {Human: ENSG00000072518, MARK2, microtubule affinity regulating kinase 2, [RH, Score=713, Expect=0.0]; ENSG00000075413, MARK3, microtubule affinity regulating kinase 3, [RH, Score=709, Expect=0.0]; ENSG00000116141, MARK1, microtubule affinity regulating kinase 1, [RH, Score=707, Expect=0.0]} {Mouse: ENSMUSG00000024969, Mark2, MAP/microtubule affinity regulating kinase 2, [RH, Score=716, Expect=0.0]; ENSMUSG00000026620, Mark1, MAP/microtubule affinity regulating kinase 1, [RH, Score=709, Expect=0.0]; ENSMUSG00000007411, Mark3, MAP/microtubule affinity regulating kinase 3, [RH, Score=708, Expect=0.0]} {Dmel: FBgn0260934, par-1, [RH, Score=542, Expect=0.0]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [RH, Score=526, Expect=3e-171]} {Smed: dd_Smed_v6_3685_0_1, dd_Smed_v6_3685_0_1, [RH, Score=558, Expect=0.0]} {RNA1509_20387} {RNA1310_3129.1} {RNA815_1041.1}
63. MligTC455_52646 1059 22.07 Mlig455_035837

Neo: -

Age: -

Region-enriched R2: 1.308/0.00778

 FBXL13 1.788 - - 0.837 0.951 - - Mlig455_035837 {REF} {Length: 2683} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=92.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=69.2]; Leucine rich repeat [PF13855.8, score=34.6]; F-box-like [PF12937.9, score=21.2]; F-box domain [PF00646.35, score=19.5]} {Human: ENSG00000161040, FBXL13, F-box and leucine rich repeat protein 13, [RH, Score=370, Expect=3e-116]} {Mouse: ENSMUSG00000048520, Fbxl13, F-box and leucine-rich repeat protein 13, [RH, Score=367, Expect=1e-114]} {Dmel: FBgn0038385, Fbxl7, F-box and leucine-rich repeat protein 7, [Score=104, Expect=1e-22]} {Celegans: WBGene00015350, fbxl-1, Uncharacterized F-box/LRR-repeat protein C02F5.7, [Score=122, Expect=2e-29]} {Smed: dd_Smed_v6_14890_0_1, dd_Smed_v6_14890_0_1, [RH, Score=597, Expect=0.0]} {RNA1509_11787, RNA1509_47513} {RNA1310_7673, RNA1509_11787, RNA1509_47513} {RNA1509_11787, RNA1509_47513, RNA815_2345.1}
64. MligTC455_17819 776 16.16 Mlig455_029976

Neo: -

Age: Down-Up-Down

 GUCA1B 1.76 - - 0.804 0.956 - - Mlig455_029976 {REF} {Length: 1140} {Pfam: EF hand [PF00036.34, score=74.9]; EF-hand domain pair [PF13499.8, score=71.2]; EF hand [PF13202.8, score=63.7]; EF-hand domain [PF13405.8, score=63.2]; EF-hand domain pair [PF13833.8, score=52.6]} {Human: ENSG00000112599, GUCA1B, guanylate cyclase activator 1B, [Score=69.7, Expect=1e-14]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=52.0, Expect=8e-09]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=51.6, Expect=2e-08]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=51.6, Expect=2e-08]; ENSMUSG00000028310, Ppp3r2, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II), [Score=50.4, Expect=1e-07]; ENSMUSG00000033953, Ppp3r1, protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I), [Score=50.4, Expect=8e-08]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=50.4, Expect=5e-08]} {Celegans: WBGene00003565, ncs-3, Neuronal Calcium Sensor family, [Score=67.8, Expect=3e-14]} {Smed: dd_Smed_v6_14450_0_1, dd_Smed_v6_14450_0_1, [Score=52.0, Expect=1e-08]} {RNA1509_25226} {RNA1310_34058} {RNA815_15719}
65. MligTC455_47067 973 20.27 Mlig455_008123

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.330

 1.76 0.799 - - 0.961 - - Mlig455_008123 {REF} {Length: 1559} {Pfam: Cilia- and flagella-associated protein HOATZ-like [PF17664.3, score=53.1]} {RNA1509_14506, RNA1509_58252} {RNA1310_1256, RNA1509_14506, RNA1509_58252} {RNA1509_14506, RNA1509_58252, RNA815_9775.1}
66. MligTC455_45207 1239 25.82 Mlig455_032063

Neo: -

Age: Down-Down-Up

 1.754 - - 0.776 0.978 - - Mlig455_032063 {REF} {Length: 2507} {RNA1509_35528} {RNA1310_3497.1} {RNA815_14551}
67. MligTC455_27915 1941 40.44 Mlig455_043371

Neo: -

Age: -

 1.738 - - - 0.962 0.776 - Mlig455_043371 {REF} {Length: 1120} {Pfam: Domain of unknown function (DUF4515) [PF14988.8, score=105.7]} {Mouse: ENSMUSG00000098176, Ccdc166, coiled-coil domain containing 166, [RH, Score=107, Expect=4e-26]} {Smed: dd_Smed_v6_13384_0_1, dd_Smed_v6_13384_0_1, [RH, Score=126, Expect=2e-34]} {RNA1509_14562, RNA1509_19268} {RNA1310_32791.2, RNA1509_14562, RNA1509_19268} {RNA1509_14562, RNA1509_19268, RNA815_15652}
68. MligTC455_41599 3357 69.95 Mlig455_064396

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.297

 PDZK1 1.724 - - - 0.954 0.770 - Mlig455_064396 {REF} {Length: 1538} {Pfam: PDZ domain [PF00595.26, score=25.5]} {Human: ENSG00000174827, PDZK1, PDZ domain containing 1, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [Score=46.2, Expect=1e-05]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=55.1, Expect=1e-08]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=63.5, Expect=3e-12]} {RNA1509_4967} {RNA1310_15027} {RNA815_6549.1}
69. MligTC455_32519 147 3.06 Mlig455_017549

Neo: -

Age: logFC(26M/2M)=-0.495

 NWD2 1.723 0.772 - - - 0.951 - Mlig455_017549 {REF} {Length: 6334} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA ATPase domain [PF13191.8, score=38.4]; NACHT domain [PF05729.14, score=34.5]; AAA domain [PF13481.8, score=20.7]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=347, Expect=8e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=340, Expect=1e-96]} {Dmel: FBgn0038397, CG10185, [Score=472, Expect=9e-143]} {Celegans: WBGene00020254, T05C3.2, [Score=527, Expect=1e-162]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=380, Expect=2e-110]} {RNA1509_23488} {RNA1310_497.1} {RNA815_237}
70. MligTC455_41598 3360 70 Mlig455_064369

Neo: -

Age: Down-Up-Up

 PDZK1 1.721 - - - 0.953 0.768 - Mlig455_064369 {REF} {Length: 1555} {Pfam: PDZ domain [PF00595.26, score=24.0]} {Human: ENSG00000174827, PDZK1, PDZ domain containing 1, [Score=50.8, Expect=7e-07]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [Score=47.0, Expect=6e-06]; ENSMUSG00000038298, Pdzk1, PDZ domain containing 1, [Score=47.0, Expect=1e-05]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=58.9, Expect=7e-10]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=63.5, Expect=4e-12]} {RNA1509_4967} {RNA1310_15027} {RNA815_6549.1}
71. MligTC455_42625 514 10.71 Mlig455_030550

Neo: -

Age: logFC(26M/2M)=-0.257

 FHAD1 1.717 - - - 0.962 0.755 - Mlig455_030550 {REF} {Length: 4380} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=46.8]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=28.5]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=94.0, Expect=1e-18]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=89.4, Expect=2e-17]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=89.4, Expect=2e-17]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=122, Expect=1e-27]} {RNA1509_16296, RNA1509_55326} {RNA1310_9155.1, RNA1509_16296, RNA1509_55326} {RNA1509_16296, RNA1509_55326, RNA815_22370}
72. MligTC455_54076 715 14.9 Mlig455_015419

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.789

 CUBN 1.717 - - 0.762 0.955 - - Mlig455_015419 {REF} {Length: 1794} {Pfam: CUB domain [PF00431.22, score=65.2]} {Human: ENSG00000107611, CUBN, cubilin, [Score=63.2, Expect=4e-10]; ENSG00000095587, TLL2, tolloid like 2, [Score=61.6, Expect=1e-09]; ENSG00000187908, DMBT1, deleted in malignant brain tumors 1, [Score=60.8, Expect=2e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=60.1, Expect=4e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=72.0, Expect=4e-13]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.9, Expect=4e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=64.7, Expect=4e-11]} {RNA1509_9300} {RNA1310_18452, RNA1509_9300} {RNA1509_9300, RNA815_8451}
73. MligTC455_18647 1244 25.91 Mlig455_063436

Neo: -

Age: -

 1.715 - 0.759 - 0.956 - - Mlig455_063436 {REF} {Length: 1503} {Pfam: BTB/POZ domain [PF00651.33, score=34.7]} {RNA1509_43600, RNA1509_45066} {RNA1310_23212, RNA1509_43600, RNA1509_45066} {RNA1509_43600, RNA1509_45066, RNA815_2283.1}
74. MligTC455_51695 429 8.93 Mlig455_011268

Neo: -

Age: Down-Down-Up

 FAM47E 1.712 0.969 - 0.743 - - - Mlig455_011268 {REF} {Length: 2157} {Pfam: FAM47 family [PF14642.8, score=51.4]} {Human: ENSG00000189157, FAM47E, family with sequence similarity 47 member E, [RH, Score=137, Expect=1e-35]} {Mouse: ENSMUSG00000078315, Fam47c, family with sequence similarity 47, member C, [RH, Score=119, Expect=5e-29]} {Smed: dd_Smed_v6_10346_0_1, dd_Smed_v6_10346_0_1, [RH, Score=294, Expect=2e-95]} {RNA1509_32582, RNA1509_8031} {RNA1310_12665, RNA1509_32582, RNA1509_8031} {RNA1509_32582, RNA1509_8031, RNA815_4489.1}
75. MligTC455_47575 203 4.23 Mlig455_068827

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.457

 MAN1C1 1.707 - - 0.753 - 0.954 - Mlig455_068827 {REF} {Length: 3468} {Pfam: Glycosyl hydrolase family 47 [PF01532.22, score=378.5]} {Human: ENSG00000117643, MAN1C1, mannosidase alpha class 1C member 1, [Score=268, Expect=7e-82]; ENSG00000198162, MAN1A2, mannosidase alpha class 1A member 2, [Score=268, Expect=2e-81]} {Mouse: ENSMUSG00000037306, Man1c1, mannosidase, alpha, class 1C, member 1, [Score=267, Expect=2e-81]; ENSMUSG00000008763, Man1a2, mannosidase, alpha, class 1A, member 2, [Score=267, Expect=2e-81]; ENSMUSG00000003746, Man1a, mannosidase 1, alpha, [Score=264, Expect=6e-80]} {Dmel: FBgn0259170, alpha-Man-Ia, alpha-Mannosidase class I a, [Score=268, Expect=1e-81]} {Celegans: WBGene00008258, mans-2, Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5, [Score=250, Expect=1e-75]} {Smed: dd_Smed_v6_6801_0_1, dd_Smed_v6_6801_0_1, [Score=267, Expect=3e-82]} {RNA1509_48511, RNA1509_9530} {RNA1310_9474.1, RNA1509_48511, RNA1509_9530} {RNA1509_48511, RNA1509_9530, RNA815_6962}
76. MligTC455_13001 3958 82.45 Mlig455_058752

Neo: -

Age: logFC(26M/2M)=-0.388

 CALML3 1.706 - - - - 0.740 0.966 Mlig455_058752 {REF} {Length: 1160} {Pfam: EF hand [PF00036.34, score=117.6]; EF-hand domain pair [PF13499.8, score=111.2]; EF-hand domain [PF13405.8, score=93.1]; EF hand [PF13202.8, score=91.8]; EF-hand domain pair [PF13833.8, score=82.4]; EF-hand domain [PF14658.8, score=44.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=32.1]; Tellurite resistance protein TerB [PF05099.15, score=19.5]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=116, Expect=5e-33]; ENSG00000160014, CALM3, calmodulin 3, [Score=115, Expect=1e-32]; ENSG00000198668, CALM1, calmodulin 1, [Score=115, Expect=7e-33]; ENSG00000143933, CALM2, calmodulin 2, [Score=115, Expect=1e-32]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=115, Expect=7e-33]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=115, Expect=7e-33]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=115, Expect=7e-33]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=112, Expect=6e-32]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=112, Expect=5e-32]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=112, Expect=4e-32]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=112, Expect=3e-32]} {RNA1509_6844} {RNA1310_36879} {RNA815_5954.1}
77. MligTC455_43980 756 15.74 Mlig455_010403

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.562

 CALM3 1.692 - - - 0.956 0.736 - Mlig455_010403 {REF} {Length: 1382} {Pfam: EF-hand domain pair [PF13499.8, score=113.0]; EF hand [PF00036.34, score=99.8]; EF-hand domain pair [PF13833.8, score=95.7]; EF-hand domain [PF13405.8, score=85.4]; EF hand [PF13202.8, score=61.7]; EF-hand domain [PF14658.8, score=49.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=28.1]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=154, Expect=4e-48]; ENSG00000198668, CALM1, calmodulin 1, [Score=154, Expect=4e-48]; ENSG00000143933, CALM2, calmodulin 2, [Score=154, Expect=4e-48]} {Mouse: ENSMUSG00000036438, Calm2, calmodulin 2, [Score=154, Expect=2e-48]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=154, Expect=2e-48]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=154, Expect=2e-48]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=153, Expect=2e-48]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=152, Expect=4e-48]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=152, Expect=3e-48]} {RNA1509_32040} {RNA1310_21110, RNA1509_32040} {RNA1509_32040, RNA815_14492.1}
78. MligTC455_15810 1023 21.32 Mlig455_039929

Neo: Irradiation

Age: -

Region-enriched R4: 1.741/0.00021

 PAQR3 1.688 - - - 0.956 0.732 - Mlig455_039929 {REF} {Length: 1545} {TRANSSPLICED} {Pfam: Haemolysin-III related [PF03006.22, score=138.1]} {Human: ENSG00000163291, PAQR3, progestin and adipoQ receptor family member 3, [RH, Score=230, Expect=4e-73]} {Mouse: ENSMUSG00000055725, Paqr3, progestin and adipoQ receptor family member III, [RH, Score=228, Expect=2e-72]} {Dmel: FBgn0038256, CG7530, [RH, Score=184, Expect=4e-55]} {Celegans: WBGene00013457, paqr-3, Progestin and AdipoQ Receptor family, [RH, Score=169, Expect=2e-49]} {Smed: dd_Smed_v6_10397_0_1, dd_Smed_v6_10397_0_1, [RH, Score=258, Expect=1e-84]} {RNA1509_31955} {RNA1310_5306} {RNA815_8277}
79. MligTC455_52765 1250 26.03 Mlig455_020837, Mlig455_020942

Neo: -

Age: logFC(26M/2M)=-0.658

 1.678 - - - 0.962 0.716 -

Mlig455_020837 {REF} {Length: 1127} {Pfam: Zinc finger, ZZ type [PF00569.19, score=42.1]; PB1 domain [PF00564.26, score=29.6]} {RNA1509_14616} {RNA1310_27419.2} {RNA815_11811}

Mlig455_020942 {REF} {Length: 1302} {Pfam: Zinc finger, ZZ type [PF00569.19, score=42.2]; PB1 domain [PF00564.26, score=29.6]} {RNA1509_14616} {RNA1310_27419.1} {RNA815_11811}
80. MligTC455_18404 390 8.12 Mlig455_027551

Neo: -

Age: Down-Up-Down

 1.675 - 0.725 - - 0.950 - Mlig455_027551 {REF} {Length: 4230} {RNA1509_17329} {RNA1310_2058.1, RNA1509_17329} {RNA1509_17329, RNA815_426}
81. MligTC455_08944 160 3.34 Mlig455_050947

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.619

 1.665 - - - 0.711 0.954 - Mlig455_050947 {REF} {Length: 1135} {RNA1310_13460.1} {RNA815_53760}
82. MligTC455_36285 232 4.84 Mlig455_049585

Neo: -

Age: -

Region-enriched R2: 2.764/0.02680

 SGSM1 1.661 0.950 - 0.711 - - - Mlig455_049585 {REF} {Length: 3668} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=117.8]; Rab-binding domain (RBD) [PF12068.10, score=107.7]; RUN domain [PF02759.21, score=79.1]} {Human: ENSG00000167037, SGSM1, small G protein signaling modulator 1, [RH, Score=428, Expect=4e-132]} {Mouse: ENSMUSG00000038351, Sgsm2, small G protein signaling modulator 2, [RH, Score=637, Expect=0.0]} {Dmel: FBgn0031116, CG1695, [RH, Score=432, Expect=5e-133]} {Celegans: WBGene00008018, tbc-8, TBC (Tre-2/Bub2/Cdc16) domain family, [RH, Score=421, Expect=2e-131]} {Smed: dd_Smed_v6_12130_0_1, dd_Smed_v6_12130_0_1, [RH, Score=609, Expect=0.0]} {RNA1509_48678} {RNA1310_9224, RNA1509_48678} {RNA1509_48678, RNA815_14977}
83. MligTC455_23078 287 5.98 Mlig455_011747

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.620

 CUBN 1.651 - - - 0.701 0.950 - Mlig455_011747 {REF} {Length: 2191} {Pfam: EGF-like domain [PF00008.29, score=33.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=52.4, Expect=2e-07]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=53.9, Expect=3e-08]} {RNA1509_38266} {RNA1310_23149} {RNA815_9585.1}
84. MligTC455_34258 536 11.17 Mlig455_039100

Neo: -

Age: Up-Down-Down

 UNC80 0.982 0.982 - - - - - Mlig455_039100 {REF} {Length: 6695} {Pfam: Protein UNC80 [PF19424.1, score=644.7]} {Human: ENSG00000144406, UNC80, unc-80 homolog, NALCN channel complex subunit, [Score=622, Expect=0.0]} {Mouse: ENSMUSG00000055567, Unc80, unc-80, NALCN activator, [Score=619, Expect=0.0]} {Dmel: FBgn0039536, unc80, uncoordinated 80, [Score=642, Expect=0.0]} {Celegans: WBGene00006812, unc-80, [Score=620, Expect=0.0]} {Smed: dd_Smed_v6_5118_0_1, dd_Smed_v6_5118_0_1, [Score=854, Expect=0.0]} {RNA1509_23382} {RNA1310_463.1} {RNA815_194.1}
85. MligTC455_26409 560 11.67 Mlig455_009119, Mlig455_058078

Neo: -

Age: logFC(26M/2M)=-0.332

 MX1 0.976 - - - - 0.976 -

Mlig455_009119 {REF} {Length: 7633} {Pfam: Dynamin central region [PF01031.22, score=173.3]; Dynamin family [PF00350.25, score=127.6]; Dynamin GTPase effector domain [PF02212.20, score=37.9]; 50S ribosome-binding GTPase [PF01926.25, score=19.2]} {Human: ENSG00000157601, MX1, MX dynamin like GTPase 1, [RH, Score=330, Expect=6e-101]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=314, Expect=2e-95]} {Dmel: FBgn0003392, shi, shibire, [Score=185, Expect=2e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=181, Expect=3e-47]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=189, Expect=5e-50]} {RNA1509_7993} {RNA1310_3641.1, RNA1509_7993} {RNA1509_7993, RNA815_1668.1}

Mlig455_058078 {REF} {Length: 4391} {Pfam: Dynamin central region [PF01031.22, score=173.3]; Dynamin family [PF00350.25, score=127.8]; Dynamin GTPase effector domain [PF02212.20, score=38.2]; 50S ribosome-binding GTPase [PF01926.25, score=19.5]} {Human: ENSG00000157601, MX1, MX dynamin like GTPase 1, [RH, Score=330, Expect=7e-102]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=315, Expect=4e-96]} {Dmel: FBgn0003392, shi, shibire, [Score=185, Expect=2e-48]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=182, Expect=2e-47]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=189, Expect=3e-50]} {RNA1509_50755} {RNA1310_3641.1, RNA1509_50755} {RNA1509_50755, RNA815_1668.1}
86. MligTC455_53093 333 6.93 Mlig455_002441

Neo: -

Age: Down-Up-Down

Region-enriched R2: 2.548/0.03843

 SOX2 0.971 - - - - 0.971 - Mlig455_002441 {REF} {Length: 2143} {Pfam: HMG (high mobility group) box [PF00505.21, score=94.8]; HMG-box domain [PF09011.12, score=43.0]; Protein of unknown function (DUF2722) [PF10846.10, score=21.2]; VIT family [PF01988.21, score=18.8]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=179, Expect=6e-54]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=179, Expect=4e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=162, Expect=1e-44]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [Score=169, Expect=7e-51]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=158, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352} {RNA815_15989}
87. MligTC455_49732 4439 92.49 Mlig455_007344, Mlig455_066660

Neo: -

Age: Down-Up-Down

 0.969 - - - 0.969 - -

Mlig455_007344 {REF} {Length: 512} {Pfam: Domain of unknown function (DUF4558) [PF15104.8, score=59.9]} {RNA1509_46663} {RNA1310_54663.1} {RNA815_25536.3}

Mlig455_066660 {REF} {Length: 1859} {Pfam: Domain of unknown function (DUF4558) [PF15104.8, score=59.6]} {RNA1509_14029, RNA1509_27746} {RNA1310_54663.1, RNA1509_14029, RNA1509_27746} {RNA1509_14029, RNA1509_27746, RNA815_25536.2}
88. MligTC455_46887 1771 36.89 Mlig455_023150

Neo: -

Age: logFC(26M/2M)=-0.580

 SLC25A14 0.968 0.968 - - - - - Mlig455_023150 {REF} {Length: 2121} {Pfam: Mitochondrial carrier protein [PF00153.29, score=221.0]} {Human: ENSG00000102078, SLC25A14, solute carrier family 25 member 14, [RH, Score=287, Expect=1e-95]; ENSG00000174032, SLC25A30, solute carrier family 25 member 30, [RH, Score=281, Expect=2e-93]} {Mouse: ENSMUSG00000031105, Slc25a14, solute carrier family 25 (mitochondrial carrier, brain), member 14, [RH, Score=284, Expect=2e-94]; ENSMUSG00000022003, Slc25a30, solute carrier family 25, member 30, [RH, Score=281, Expect=9e-94]} {Dmel: FBgn0036199, Bmcp, [RH, Score=259, Expect=8e-85]} {Celegans: WBGene00015186, misc-1, MItochondrial Solute Carrier, [Score=166, Expect=1e-48]} {Smed: dd_Smed_v6_8945_0_8, dd_Smed_v6_8945_0_8, [RH, Score=250, Expect=1e-81]} {RNA1509_12259} {RNA1310_31014} {RNA815_1562.1}
89. MligTC455_33472 218 4.54 Mlig455_002628, Mlig455_029723, Mlig455_030658, Mlig455_034491, Mlig455_066243, Mlig455_066259

Neo: Int S/G2/M

Age: -

Region-enriched R4: 3.344/0.00914

 0.965 - - - - 0.965 -

Mlig455_002628 {REF} {Length: 556} {NoTransDecoderORF} {RNA1509_55687} {RNA1310_13666} {RNA815_21259}

Mlig455_029723 {REF} {Length: 545} {NoTransDecoderORF} {RNA1509_55687} {RNA1310_13666} {RNA815_21259}

Mlig455_030658 {REF} {Length: 1374} {NoTransDecoderORF} {RNA1509_26436, RNA1509_55687} {RNA1310_15512.1, RNA1509_26436} {RNA1509_26436, RNA815_21259}

Mlig455_034491 {REF} {Length: 1284} {NoTransDecoderORF} {RNA1509_55687} {RNA1310_13666} {RNA815_21259}

Mlig455_066243 {REF} {Length: 631} {NoTransDecoderORF} {RNA1509_26436} {RNA1310_13666} {RNA815_21259}

Mlig455_066259 {REF} {Length: 1349} {NoTransDecoderORF} {RNA1509_55687} {RNA1310_13666} {RNA815_21259}
90. MligTC455_18038 40 0.83 Mlig455_004608

Neo: -

Age: -

 0.963 - - - - 0.963 - Mlig455_004608 {REF} {Length: 632} {NoTransDecoderORF} {RNA1509_37916} {RNA1310_23706} {RNA815_34585}
91. MligTC455_33668 60 1.25 Mlig455_039039

Neo: -

Age: Up-Down-Up

 0.963 - - - - 0.963 - Mlig455_039039 {REF} {Length: 4009} {Pfam: SAP domain [PF02037.29, score=37.9]} {RNA1509_38222, RNA1509_51141} {RNA1310_17762.1, RNA1509_38222, RNA1509_51141} {RNA1509_38222, RNA1509_51141, RNA815_12470.1}
92. MligTC455_52742 2743 57.15 Mlig455_019982

Neo: -

Age: -

Region-enriched R5: 1.776/0.00000

 TBATA 0.962 - - - 0.962 - - Mlig455_019982 {REF} {Length: 2167} {Pfam: SPATIAL [PF15256.8, score=102.4]} {Human: ENSG00000166220, TBATA, thymus, brain and testes associated, [RH, Score=57.8, Expect=3e-09]} {Mouse: ENSMUSG00000020096, Tbata, thymus, brain and testes associated, [RH, Score=65.5, Expect=5e-12]} {Smed: dd_Smed_v6_8051_0_1, dd_Smed_v6_8051_0_1, [RH, Score=62.4, Expect=3e-11]} {RNA1509_12626, RNA1509_45918, RNA1509_48879, RNA1509_6863} {RNA1310_8923.1, RNA1509_12626, RNA1509_45918, RNA1509_6863} {RNA1509_12626, RNA1509_45918, RNA1509_6863, RNA815_3957.1}
93. MligTC455_16725 225 4.69 Mlig455_056078

Neo: -

Age: Up-Down-Down

 PTEN 0.96 - - - - 0.960 - Mlig455_056078 {REF} {Length: 4586} {TRANSSPLICED} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=72.2]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=22.7]; Protein-tyrosine phosphatase [PF00102.29, score=18.5]} {Human: ENSG00000284792, PTEN, phosphatase and tensin homolog, [Score=269, Expect=2e-83]; ENSG00000171862, PTEN, phosphatase and tensin homolog, [Score=266, Expect=2e-84]} {Mouse: ENSMUSG00000013663, Pten, phosphatase and tensin homolog, [Score=266, Expect=1e-84]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=219, Expect=2e-66]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=150, Expect=5e-39]} {Smed: dd_Smed_v6_7478_0_1, dd_Smed_v6_7478_0_1, [RH, Score=230, Expect=5e-71]} {RNA1509_17397} {RNA1310_7531.2, RNA1509_17397} {RNA1509_17397, RNA815_4064}
94. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

 VASH2 0.96 - - - - 0.960 - Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
95. MligTC455_49551 857 17.85 Mlig455_011653

Neo: -

Age: -

 MAP3K19 0.96 - - - 0.960 - - Mlig455_011653 {REF} {Length: 5210} {Pfam: Protein kinase domain [PF00069.27, score=148.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=130.0]; Caspase domain [PF00656.24, score=120.8]; Ankyrin repeats (3 copies) [PF12796.9, score=73.2]; Ankyrin repeats (many copies) [PF13857.8, score=57.3]; Ankyrin repeat [PF00023.32, score=47.2]; Ankyrin repeats (many copies) [PF13637.8, score=44.1]; Ankyrin repeat [PF13606.8, score=42.1]; Fungal protein kinase [PF17667.3, score=18.8]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=126, Expect=7e-30]; ENSG00000060237, WNK1, WNK lysine deficient protein kinase 1, [Score=121, Expect=5e-27]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=121, Expect=2e-28]; ENSMUSG00000045962, Wnk1, WNK lysine deficient protein kinase 1, [Score=121, Expect=3e-27]; ENSMUSG00000041245, Wnk3, WNK lysine deficient protein kinase 3, [Score=117, Expect=1e-26]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=109, Expect=3e-24]} {Celegans: WBGene00006941, wnk-1, Serine/threonine-protein kinase WNK, [Score=106, Expect=5e-23]} {Smed: dd_Smed_v6_417_0_1, dd_Smed_v6_417_0_1, [Score=101, Expect=2e-23]} {RNA1509_2733, RNA1509_28241} {RNA1310_1474, RNA1509_28241} {RNA1509_28241, RNA815_848}
96. MligTC455_35664 1772 36.91 Mlig455_020393, Mlig455_028392, Mlig455_058437

Neo: -

Age: logFC(26M/2M)=-0.217

Region-enriched R4: 1.033/0.04115

 CLHC1 0.958 - - - - - 0.958

Mlig455_020393 {REF} {Length: 1999} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.3]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [RH, Score=155, Expect=8e-40]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [RH, Score=160, Expect=8e-42]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=51.2, Expect=2e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [RH, Score=145, Expect=4e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_028392 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Clathrin-H-link [PF13838.8, score=35.7]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=110, Expect=4e-25]} {Mouse: ENSMUSG00000047126, Cltc, clathrin, heavy polypeptide (Hc), [Score=54.7, Expect=3e-07]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.4, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=114, Expect=1e-26]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}

Mlig455_058437 {REF} {Length: 2088} {Pfam: Translin-associated factor X-interacting N-terminus [PF15739.7, score=57.4]; Clathrin-H-link [PF13838.8, score=34.4]} {Human: ENSG00000162994, CLHC1, clathrin heavy chain linker domain containing 1, [Score=153, Expect=3e-39]} {Mouse: ENSMUSG00000020461, Clhc1, clathrin heavy chain linker domain containing 1, [Score=158, Expect=4e-41]} {Celegans: WBGene00011867, chc-1, Probable clathrin heavy chain 1, [Score=50.8, Expect=3e-06]} {Smed: dd_Smed_v6_9605_0_1, dd_Smed_v6_9605_0_1, [Score=144, Expect=9e-37]} {RNA1509_8364} {RNA1310_5794.1} {RNA815_1706}
97. MligTC455_49709 228 4.74 Mlig455_024769, Mlig455_038951

Neo: -

Age: -

 0.958 - - - - 0.958 -

Mlig455_024769 {REF} {Length: 560} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=104.8]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=1e-15]} {RNA1509_31268} {RNA1310_89323} {RNA815_51068}

Mlig455_038951 {REF} {Length: 1037} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=74.6]} {Smed: dd_Smed_v6_19123_0_4, dd_Smed_v6_19123_0_4, [Score=60.8, Expect=4e-10]} {RNA1509_31268} {RNA1310_10452.2} {RNA815_28501}
98. MligTC455_12261 66 1.38 Mlig455_013614

Neo: -

Age: -

 0.957 - - - - 0.957 - Mlig455_013614 {REF} {Length: 2553} {RNA1310_13989} {RNA815_35164}
99. MligTC455_34393 332 6.91 Mlig455_000981, Mlig455_037508

Neo: -

Age: -

 AC093830.1 0.956 0.956 - - - - -

Mlig455_000981 {REF} {Length: 3619} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=184.0]} {Human: ENSG00000262505, AC093830.1, acid sensing ion channel subunit family member 5, [Score=53.1, Expect=1e-06]; ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=52.8, Expect=2e-06]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=68.9, Expect=1e-11]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.4, Expect=1e-06]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=84.3, Expect=1e-16]} {RNA1509_28049} {RNA1310_8320.2} {RNA815_4456}

Mlig455_037508 {REF} {Length: 3555} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=184.0]} {Human: ENSG00000262505, AC093830.1, acid sensing ion channel subunit family member 5, [Score=53.1, Expect=1e-06]; ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=52.8, Expect=2e-06]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=69.3, Expect=9e-12]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.0, Expect=1e-06]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=84.7, Expect=8e-17]} {RNA1509_28049} {RNA1310_8320.1} {RNA815_4456}
100. MligTC455_46888 3493 72.77 Mlig455_023236

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.334

Regeneration-downregulated TP: -1.196

Regeneration-depleted TP: -1.196

 SLC25A14 0.956 0.956 - - - - - Mlig455_023236 {REF} {Length: 4876} {Pfam: Mitochondrial carrier protein [PF00153.29, score=159.1]} {Human: ENSG00000102078, SLC25A14, solute carrier family 25 member 14, [Score=216, Expect=1e-68]; ENSG00000174032, SLC25A30, solute carrier family 25 member 30, [Score=213, Expect=2e-68]} {Mouse: ENSMUSG00000031105, Slc25a14, solute carrier family 25 (mitochondrial carrier, brain), member 14, [Score=218, Expect=2e-69]; ENSMUSG00000022003, Slc25a30, solute carrier family 25, member 30, [Score=213, Expect=6e-68]} {Dmel: FBgn0036199, Bmcp, [Score=186, Expect=2e-57]} {Celegans: WBGene00015186, misc-1, MItochondrial Solute Carrier, [Score=137, Expect=1e-38]} {Smed: dd_Smed_v6_8945_0_8, dd_Smed_v6_8945_0_8, [Score=186, Expect=1e-57]} {RNA1509_23992, RNA1509_51810} {RNA1310_10029, RNA1509_51810} {RNA1509_51810, RNA815_7763.1}

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