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Results for MligTC455_23565

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}

Cumulative graph for MligTC455_23565

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.217 6.23 0.71780 1.00000
RegionR2 0.758 6.23 0.01086 0.10597
RegionR3 -0.049 6.23 0.84924 1.00000
RegionR4 0.522 6.23 0.08964 0.28577
RegionR5 -0.468 6.23 0.06929 0.23643
RegionR6 0.62 6.23 0.01313 0.19877
RegionR7 -0.717 6.23 0.03243 0.34309
RegionR8 -0.448 6.23 0.27103 0.89402

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.987 6.23 0.26483 0.97007
RegenerationR2 0.336 6.23 0.23103 0.67844
RegenerationR3 0.317 6.23 0.30230 0.73357
RegenerationR4 -0.143 6.23 0.65238 0.93445
RegenerationR5 0.215 6.23 0.48050 0.84686
RegenerationR6 -0.71 6.23 0.02114 0.18034
RegenerationBL -0.174 6.23 0.59331 0.94260
RegenerationTP 0.507 6.23 0.15722 0.58502


Genes with expression patterns similar to MligTC455_23565

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}
2. MligTC455_50676 3764 78.41 Mlig455_024344

Neo: -

Age: -

IQCD 4.279 0.842 0.772 - 0.947 0.958 0.760 Mlig455_024344 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_1833, RNA1509_46413} {RNA1310_4220.1, RNA1509_46413} {RNA1509_46413, RNA815_1223.1}
3. MligTC455_50677 3742 77.95 Mlig455_024461

Neo: -

Age: -

IQCD 4.239 0.802 0.760 - 0.950 0.963 0.764 Mlig455_024461 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1310_4220.1, RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931, RNA815_1223.1}
4. MligTC455_27219 4029 83.93 Mlig455_007044

Neo: -

Age: logFC(26M/2M)=-0.389

TEKT2 4.165 - 0.789 0.788 0.954 0.911 0.723 Mlig455_007044 {REF} {Length: 1859} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=375.3]} {Human: ENSG00000092850, TEKT2, tektin 2, [Score=380, Expect=2e-129]} {Mouse: ENSMUSG00000028845, Tekt2, tektin 2, [Score=349, Expect=1e-117]} {Dmel: FBgn0034816, CG3085, [Score=183, Expect=2e-53]} {Celegans: WBGene00019828, R02E12.4, [Score=72.8, Expect=1e-13]} {Smed: dd_Smed_v6_2339_0_1, dd_Smed_v6_2339_0_1, [Score=503, Expect=1e-178]} {RNA1509_1922} {RNA1310_13089.2} {RNA815_4479}
5. MligTC455_37360 5178 107.87 Mlig455_043000

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.956

CFAP52 4.135 - 0.832 0.791 0.762 0.973 0.777 Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855}
6. MligTC455_37361 5370 111.88 Mlig455_043035

Neo: -

Age: logFC(26M/2M)=-0.378

CFAP52 4.113 - 0.834 0.764 0.773 0.972 0.770 Mlig455_043035 {REF} {Length: 2490} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.1]; WD40-like domain [PF17005.7, score=27.1]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=441, Expect=1e-145]} {Celegans: WBGene00004895, smu-1, SMU-1; Suppressor of Mec and Unc defects, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=841, Expect=0.0]} {RNA1509_1341} {RNA1310_8859, RNA1509_1341} {RNA1509_1341, RNA815_2855}
7. MligTC455_43293 2619 54.57 Mlig455_001393

Neo: -

Age: -

Region-specific R2: 1.579

ANXA7 4.075 - 0.706 0.756 0.955 0.816 0.842 Mlig455_001393 {REF} {Length: 4698} {Pfam: Annexin [PF00191.22, score=268.6]} {Human: ENSG00000138279, ANXA7, annexin A7, [RH, Score=307, Expect=6e-98]} {Mouse: ENSMUSG00000021814, Anxa7, annexin A7, [RH, Score=301, Expect=8e-96]} {Dmel: FBgn0000083, AnxB9, Annexin B9, [Score=259, Expect=4e-82]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=261, Expect=2e-81]} {Smed: dd_Smed_v6_1735_0_1, dd_Smed_v6_1735_0_1, [Score=270, Expect=6e-86]} {RNA1509_5239} {RNA1310_11340, RNA1509_5239} {RNA1509_5239, RNA815_3977}
8. MligTC455_44301 1697 35.36 Mlig455_000545

Neo: -

Age: -

3.49 - 0.754 - 0.835 0.970 0.931 Mlig455_000545 {REF} {Length: 1706} {TRANSSPLICED} {Smed: dd_Smed_v6_6108_0_1, dd_Smed_v6_6108_0_1, [RH, Score=190, Expect=9e-63]} {RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1310_30744, RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1509_16536, RNA1509_27118, RNA1509_9934, RNA815_13864}
9. MligTC455_44365 1412 29.41 Mlig455_002492

Neo: -

Age: logFC(26M/2M)=0.553

MYCBPAP 3.466 - 0.806 0.910 0.951 0.799 - Mlig455_002492 {REF} {Length: 3081} {Pfam: MYCBP-associated protein family [PF14646.8, score=368.3]} {Human: ENSG00000136449, MYCBPAP, MYCBP associated protein, [RH, Score=280, Expect=2e-80]} {Mouse: ENSMUSG00000039110, Mycbpap, MYCBP associated protein, [RH, Score=276, Expect=5e-79]} {Smed: dd_Smed_v6_11993_0_1, dd_Smed_v6_11993_0_1, [RH, Score=323, Expect=3e-97]} {RNA1509_4206} {RNA1310_3498.3} {RNA815_1306}
10. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

LEXM 3.402 - 0.808 - 0.897 0.971 0.726 Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
11. MligTC455_47868 5452 113.57 Mlig455_031216

Neo: -

Age: logFC(26M/2M)=-0.277

TEKT1 3.383 - 0.788 - 0.757 0.972 0.866 Mlig455_031216 {REF} {Length: 1751} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=439.2]} {Human: ENSG00000167858, TEKT1, tektin 1, [RH, Score=379, Expect=4e-129]} {Mouse: ENSMUSG00000020799, Tekt1, tektin 1, [RH, Score=373, Expect=9e-127]} {Dmel: FBgn0052820, CG32820, [Score=217, Expect=4e-65]} {Smed: dd_Smed_v6_3287_0_2, dd_Smed_v6_3287_0_2, [RH, Score=448, Expect=1e-156]} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1310_15062.1, RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215, RNA815_6688}
12. MligTC455_42242 1575 32.81 Mlig455_039054

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.378

PLXDC1 3.37 - 0.747 0.869 - 0.975 0.779 Mlig455_039054 {REF} {Length: 2567} {Human: ENSG00000161381, PLXDC1, plexin domain containing 1, [Score=109, Expect=1e-25]; ENSG00000120594, PLXDC2, plexin domain containing 2, [Score=107, Expect=7e-25]} {Mouse: ENSMUSG00000017417, Plxdc1, plexin domain containing 1, [Score=111, Expect=3e-26]; ENSMUSG00000026748, Plxdc2, plexin domain containing 2, [Score=107, Expect=1e-24]} {Dmel: FBgn0028331, l(1)G0289, lethal (1) G0289, [Score=97.8, Expect=1e-21]} {Celegans: WBGene00007982, pxd-1, PleXin Domain containing, [Score=112, Expect=6e-27]} {Smed: dd_Smed_v6_68203_0_1, dd_Smed_v6_68203_0_1, [Score=69.7, Expect=3e-14]} {RNA1509_49412, RNA1509_59319, RNA1509_8427} {RNA1310_7172.1, RNA1509_49412, RNA1509_59319} {RNA1509_49412, RNA1509_59319, RNA815_7707}
13. MligTC455_23041 1502 31.29 Mlig455_043274, Mlig455_043300

Neo: -

Age: -

FOXJ1 3.316 - 0.749 0.710 - 0.974 0.883

Mlig455_043274 {REF} {Length: 3849} {TRANSSPLICED} {RNA1509_6271} {RNA1310_4486.1} {RNA815_9655}

Mlig455_043300 {REF} {Length: 4018} {TRANSSPLICED} {Pfam: Forkhead domain [PF00250.20, score=92.4]; Anti-sigma-K factor rskA [PF10099.11, score=26.3]} {Human: ENSG00000129654, FOXJ1, forkhead box J1, [Score=107, Expect=5e-24]} {Mouse: ENSMUSG00000034227, Foxj1, forkhead box J1, [Score=107, Expect=2e-24]} {Dmel: FBgn0004896, fd59A, forkhead domain 59A, [Score=76.6, Expect=2e-14]} {Celegans: WBGene00006853, unc-130, [Score=83.2, Expect=4e-17]} {Smed: dd_Smed_v6_14635_0_1, dd_Smed_v6_14635_0_1, [Score=106, Expect=2e-24]} {RNA1509_6271} {RNA1310_4486.1, RNA1509_6271} {RNA1509_6271, RNA815_9655}
14. MligTC455_49237 1147 23.89 Mlig455_053089

Neo: -

Age: Down-Up-Down

CAMK4 3.296 - 0.706 0.812 - 0.953 0.825 Mlig455_053089 {REF} {Length: 2761} {Pfam: Protein kinase domain [PF00069.27, score=263.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=117.6]; Fungal protein kinase [PF17667.3, score=24.4]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000152495, CAMK4, calcium/calmodulin dependent protein kinase IV, [Score=351, Expect=4e-118]} {Mouse: ENSMUSG00000038128, Camk4, calcium/calmodulin-dependent protein kinase IV, [Score=353, Expect=3e-119]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=248, Expect=2e-79]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=245, Expect=8e-79]} {Smed: dd_Smed_v6_10731_0_1, dd_Smed_v6_10731_0_1, [Score=357, Expect=1e-122]} {RNA1509_27017, RNA1509_8403} {RNA1310_11195.2, RNA1509_27017, RNA1509_8403} {RNA1509_27017, RNA1509_8403, RNA815_9103.1}
15. MligTC455_44986 2417 50.36 Mlig455_002882

Neo: -

Age: logFC(26M/2M)=-0.453

3.29 - - 0.715 0.817 0.959 0.799 Mlig455_002882 {REF} {Length: 1187} {RNA1509_10653, RNA1509_6260} {RNA1310_22176, RNA1509_10653, RNA1509_6260} {RNA1509_10653, RNA1509_6260, RNA815_9068}
16. MligTC455_20457 1127 23.48 Mlig455_010364

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.511/0.00908

3.197 - 0.729 - 0.774 0.736 0.958 Mlig455_010364 {REF} {Length: 1164} {RNA1509_44137} {RNA1310_37019.1} {RNA815_18501.1}
17. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

MAPK15 3.186 - 0.727 0.732 - 0.973 0.754

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
18. MligTC455_52118 5757 119.94 Mlig455_069122

Neo: -

Age: logFC(26M/2M)=0.892

CFAP58 2.776 - 0.841 - - 0.968 0.967 Mlig455_069122 {REF} {Length: 3136} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=23.0]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=923, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=991, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=1e-40]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1103, Expect=0.0]} {RNA1509_282} {RNA1310_4570, RNA1509_282} {RNA1509_282, RNA815_1528}
19. MligTC455_48164 1129 23.52 Mlig455_020167

Neo: -

Age: logFC(26M/2M)=-0.425

2.715 - - - 0.858 0.964 0.893 Mlig455_020167 {REF} {Length: 1547} {RNA1509_31892} {RNA1310_30464, RNA1509_31892} {RNA1509_31892, RNA815_28823.1}
20. MligTC455_44850 2381 49.6 Mlig455_014259

Neo: -

Age: logFC(26M/2M)=-0.355

LEXM 2.686 - 0.812 - 0.912 0.962 - Mlig455_014259 {REF} {Length: 2739} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1, RNA1509_2011} {RNA1509_2011, RNA815_5377}
21. MligTC455_54334 582 12.13 Mlig455_034532

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.828/0.00360

CEP135 2.68 0.831 0.891 - - 0.958 - Mlig455_034532 {REF} {Length: 5092} {Pfam: Ezrin/radixin/moesin family [PF00769.21, score=20.7]} {Human: ENSG00000174799, CEP135, centrosomal protein 135, [Score=345, Expect=4e-102]} {Mouse: ENSMUSG00000060771, Tsga10, testis specific 10, [RH, Score=328, Expect=5e-100]} {Dmel: FBgn0036480, Cep135, Centrosomal protein 135kDa, [RH, Score=95.5, Expect=9e-20]} {Smed: dd_Smed_v6_5218_0_1, dd_Smed_v6_5218_0_1, [RH, Score=427, Expect=5e-135]} {RNA1509_41811, RNA1509_42474, RNA1509_50736} {RNA1310_1540, RNA1509_41811, RNA1509_42474, RNA1509_50736} {RNA1509_41811, RNA1509_42474, RNA1509_50736, RNA815_400.1}
22. MligTC455_22729 1065 22.18 Mlig455_006821, Mlig455_054658

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.317

Region-enriched R2: 1.624/0.00561

DNAH8 2.669 - 0.919 - - 0.964 0.786

Mlig455_006821 {REF} {Length: 14560} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=537.8]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=466.2]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=416.8]; Dynein heavy chain C-terminal domain [PF18199.3, score=324.6]; ATP-binding dynein motor region [PF12781.9, score=291.0]; P-loop containing dynein motor region D4 [PF12780.9, score=290.7]; P-loop containing dynein motor region [PF12775.9, score=226.6]; Dynein heavy chain AAA lid domain [PF18198.3, score=177.7]; Microtubule-binding stalk of dynein motor [PF12777.9, score=141.5]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=134.5]; AAA domain (dynein-related subfamily) [PF07728.16, score=81.4]; Dynein heavy chain AAA lid domain [PF17852.3, score=76.3]; AAA+ lid domain [PF17857.3, score=62.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=25.1]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=5670, Expect=0.0]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [RH, Score=5682, Expect=0.0]} {Dmel: FBgn0267432, kl-3, male fertility factor kl3, [RH, Score=4460, Expect=0.0]} {Celegans: WBGene00000485, che-3, Cytoplasmic dynein 2 heavy chain 1, [Score=980, Expect=0.0]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [RH, Score=6801, Expect=0.0]} {RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453} {RNA1310_42, RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453} {RNA1509_11311, RNA1509_12955, RNA1509_201, RNA1509_25369, RNA1509_50556, RNA1509_55453, RNA815_121}

Mlig455_054658 {REF} {Length: 1087} {Pfam: Phage integrase, N-terminal SAM-like domain [PF13495.8, score=25.6]; Phage integrase, N-terminal SAM-like domain [PF02899.19, score=24.9]} {Human: ENSG00000124721, DNAH8, dynein axonemal heavy chain 8, [RH, Score=59.3, Expect=7e-10]} {Mouse: ENSMUSG00000033826, Dnah8, dynein, axonemal, heavy chain 8, [Score=57.4, Expect=1e-08]} {Smed: dd_Smed_v6_4176_0_1, dd_Smed_v6_4176_0_1, [Score=84.0, Expect=1e-17]} {RNA1509_25369} {RNA1310_25264} {RNA815_121}
23. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

CFAP20 2.655 - - 0.768 - 0.970 0.917 Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
24. MligTC455_54125 957 19.94 Mlig455_000017

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.528/0.00489

SPEF1 2.651 - 0.839 - - 0.970 0.842 Mlig455_000017 {REF} {Length: 1279} {TRANSSPLICED} {Pfam: CH-like domain in sperm protein [PF06294.13, score=114.7]; CAMSAP CH domain [PF11971.10, score=53.6]} {Human: ENSG00000101222, SPEF1, sperm flagellar 1, [RH, Score=172, Expect=1e-52]} {Mouse: ENSMUSG00000027329, Spef1, sperm flagellar 1, [RH, Score=180, Expect=3e-56]} {Dmel: FBgn0030722, CG12395, [Score=65.5, Expect=2e-12]} {Smed: dd_Smed_v6_5648_0_1, dd_Smed_v6_5648_0_1, [RH, Score=272, Expect=5e-93]} {RNA1509_17511, RNA1509_37707, RNA1509_9365} {RNA1310_25346.1, RNA1509_17511, RNA1509_37707, RNA1509_9365} {RNA1509_17511, RNA1509_37707, RNA1509_9365, RNA815_11607}
25. MligTC455_42968 1407 29.31 Mlig455_016645

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.499

CCDC105 2.627 - 0.816 - - 0.959 0.852 Mlig455_016645 {REF} {Length: 2773} {Pfam: Tektin family [PF03148.16, score=79.1]} {Human: ENSG00000160994, CCDC105, coiled-coil domain containing 105, [RH, Score=121, Expect=1e-29]} {Mouse: ENSMUSG00000078442, Ccdc105, coiled-coil domain containing 105, [RH, Score=131, Expect=3e-33]} {Smed: dd_Smed_v6_14773_0_1, dd_Smed_v6_14773_0_1, [RH, Score=226, Expect=3e-70]} {RNA1509_10605, RNA1509_18742, RNA1509_43341} {RNA1310_6775.1, RNA1509_10605, RNA1509_18742, RNA1509_43341} {RNA1509_10605, RNA1509_18742, RNA1509_43341, RNA815_2314.1}
26. MligTC455_42241 1556 32.43 Mlig455_022714

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.239/0.02808

PLXDC1 2.619 - - 0.919 - 0.965 0.735 Mlig455_022714 {REF} {Length: 2263} {Human: ENSG00000161381, PLXDC1, plexin domain containing 1, [Score=110, Expect=5e-26]; ENSG00000120594, PLXDC2, plexin domain containing 2, [Score=105, Expect=7e-24]} {Mouse: ENSMUSG00000017417, Plxdc1, plexin domain containing 1, [Score=113, Expect=5e-27]} {Dmel: FBgn0028331, l(1)G0289, lethal (1) G0289, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00007982, pxd-1, PleXin Domain containing, [Score=109, Expect=6e-26]} {Smed: dd_Smed_v6_68203_0_1, dd_Smed_v6_68203_0_1, [Score=68.9, Expect=6e-14]} {RNA1509_8427} {RNA1310_7172.1} {RNA815_7707}
27. MligTC455_21323 1708 35.59 Mlig455_017330

Neo: -

Age: Down-Up-Up

RIIAD1 2.618 - 0.792 - - 0.957 0.869 Mlig455_017330 {REF} {Length: 587} {TRANSSPLICED} {Human: ENSG00000178796, RIIAD1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=86.7, Expect=6e-23]} {Mouse: ENSMUSG00000028139, Riiad1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=87.4, Expect=5e-23]} {Smed: dd_Smed_v6_4716_0_2, dd_Smed_v6_4716_0_2, [RH, Score=124, Expect=8e-38]} {RNA1509_4188} {RNA1310_57362} {RNA815_29384.1}
28. MligTC455_32922 646 13.45 Mlig455_037744, Mlig455_069919

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.335

Region-enriched R2: 1.859/0.01146

ANXA4 2.565 0.874 - - - 0.953 0.738

Mlig455_037744 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=312.1]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=1e-106]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=318, Expect=6e-100]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=328, Expect=2e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=317, Expect=2e-99]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=318, Expect=6e-100]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=298, Expect=7e-93]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722} {RNA1310_5582} {RNA815_3942.1}

Mlig455_069919 {REF} {Length: 3044} {TRANSSPLICED} {Pfam: Annexin [PF00191.22, score=308.6]; Fn3 associated [PF13287.8, score=30.9]; Chitobiase/beta-hexosaminidase C-terminal domain [PF13290.8, score=27.1]} {Human: ENSG00000196975, ANXA4, annexin A4, [RH, Score=330, Expect=6e-107]; ENSG00000122359, ANXA11, annexin A11, [RH, Score=316, Expect=3e-99]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [RH, Score=329, Expect=1e-106]; ENSMUSG00000021866, Anxa11, annexin A11, [RH, Score=315, Expect=1e-98]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [RH, Score=316, Expect=3e-99]} {Celegans: WBGene00003589, nex-2, Annexin, [RH, Score=297, Expect=3e-92]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [RH, Score=726, Expect=0.0]} {RNA1509_19722, RNA1509_52903} {RNA1310_5582, RNA1509_19722, RNA1509_52903} {RNA1509_19722, RNA1509_52903, RNA815_3942.1}
29. MligTC455_19007 1131 23.57 Mlig455_044120

Neo: -

Age: -

2.534 - - - 0.806 0.964 0.764 Mlig455_044120 {REF} {Length: 3090} {TRANSSPLICED} {Smed: dd_Smed_v6_14979_0_1, dd_Smed_v6_14979_0_1, [RH, Score=170, Expect=8e-50]} {RNA1509_26326, RNA1509_52456} {RNA1310_23856, RNA1509_26326, RNA1509_52456} {RNA1509_26326, RNA1509_52456, RNA815_10081}
30. MligTC455_50996 449 9.36 Mlig455_002019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.319

Region-enriched R2: 1.520/0.04245

TRIM71 2.502 - - - 0.717 0.984 0.801 Mlig455_002019 {REF} {Length: 2281} {Pfam: NHL repeat [PF01436.23, score=74.6]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=79.3, Expect=3e-15]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=76.3, Expect=3e-14]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=79.7, Expect=2e-15]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=76.3, Expect=2e-14]} {Dmel: FBgn0265356, tn, thin, [Score=94.0, Expect=3e-20]} {Celegans: WBGene00003026, lin-41, [Score=80.5, Expect=5e-16]} {Smed: dd_Smed_v6_13659_0_1, dd_Smed_v6_13659_0_1, [RH, Score=102, Expect=2e-24]} {RNA1509_17378} {RNA1310_19512.1, RNA1509_17378} {RNA1509_17378, RNA815_7968}
31. MligTC455_18249 2857 59.52 Mlig455_031596

Neo: -

Age: logFC(26M/2M)=-0.397

2.497 - - 0.796 - 0.955 0.746 Mlig455_031596 {REF} {Length: 2515} {Smed: dd_Smed_v6_8351_0_1, dd_Smed_v6_8351_0_1, [RH, Score=57.4, Expect=1e-09]} {RNA1509_2999} {RNA1310_22585.1, RNA1509_2999} {RNA1509_2999, RNA815_9102}
32. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

XRRA1 2.491 - 0.749 - - 0.988 0.754 Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
33. MligTC455_24552 1774 36.95 Mlig455_015821, Mlig455_015828

Neo: -

Age: Up-Up-Up

IQCE 2.485 - 0.740 - - 0.961 0.784

Mlig455_015821 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}

Mlig455_015828 {REF} {Length: 2744} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1, RNA1509_3714} {RNA1509_3714, RNA815_2091.1}
34. MligTC455_36003 363 7.55 Mlig455_026590

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.251

DNAH6 2.473 0.725 0.783 - - 0.965 - Mlig455_026590 {REF} {Length: 15062} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=480.2]; P-loop containing dynein motor region D4 [PF12780.9, score=291.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=254.7]; ATP-binding dynein motor region [PF12781.9, score=232.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=229.2]; P-loop containing dynein motor region [PF12775.9, score=203.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=125.5]; Dynein heavy chain AAA lid domain [PF18198.3, score=122.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=112.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=85.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=50.9]; AAA domain [PF13401.8, score=49.6]; AAA ATPase domain [PF13191.8, score=46.7]; AAA+ lid domain [PF17857.3, score=46.7]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=45.9]; AAA domain [PF13238.8, score=23.0]; AAA domain [PF13671.8, score=20.8]; NACHT domain [PF05729.14, score=20.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.7]} {Human: ENSG00000115423, DNAH6, dynein axonemal heavy chain 6, [Score=1591, Expect=0.0]; ENSG00000185842, DNAH14, dynein axonemal heavy chain 14, [Score=1554, Expect=0.0]} {Mouse: ENSMUSG00000052861, Dnah6, dynein, axonemal, heavy chain 6, [Score=1545, Expect=0.0]} {Dmel: FBgn0283476, Dhc16F, Dynein heavy chain at 16F, [Score=1207, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=628, Expect=5e-180]} {Smed: dd_Smed_v6_10969_0_1, dd_Smed_v6_10969_0_1, [RH, Score=2792, Expect=0.0]} {RNA1509_3937, RNA1509_49112} {RNA1310_38.1, RNA1509_49112} {RNA1509_49112, RNA815_142}
35. MligTC455_43001 2139 44.57 Mlig455_004256, Mlig455_004325

Neo: -

Age: -

Region-enriched R2: 2.362/0.00019

GLUD1 2.45 - - 0.717 - 0.967 0.766

Mlig455_004256 {REF} {Length: 1969} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=185.6]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=175.9]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=639, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=639, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=639, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=613, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=641, Expect=0.0]} {RNA1509_30743} {RNA1310_2661.2} {RNA815_713.2}

Mlig455_004325 {REF} {Length: 2236} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=185.5]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=174.7]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=642, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=640, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=641, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=613, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=639, Expect=0.0]} {RNA1509_10773, RNA1509_30743} {RNA1310_2661.2, RNA1509_10773, RNA1509_30743} {RNA1509_10773, RNA1509_30743, RNA815_713.2}
36. MligTC455_24781 664 13.83 Mlig455_056890

Neo: -

Age: -

TTLL3 2.425 - - - 0.715 0.969 0.741 Mlig455_056890 {REF} {Length: 4523} {TRANSSPLICED} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=246.0]; YheC/D like ATP-grasp [PF14398.8, score=22.3]} {Human: ENSG00000214021, TTLL3, tubulin tyrosine ligase like 3, [Score=419, Expect=7e-138]; ENSG00000138892, TTLL8, tubulin tyrosine ligase like 8, [Score=417, Expect=5e-133]} {Mouse: ENSMUSG00000030276, Ttll3, tubulin tyrosine ligase-like family, member 3, [Score=451, Expect=3e-145]; ENSMUSG00000022388, Ttll8, tubulin tyrosine ligase-like family, member 8, [Score=434, Expect=8e-140]} {Dmel: FBgn0031854, TTLL3A, Tubulin tyrosine ligase-like 3A, [Score=267, Expect=2e-76]} {Celegans: WBGene00044187, ttll-9, Tubulin Tyrosine Ligase Like, [Score=113, Expect=1e-26]} {Smed: dd_Smed_v6_10244_0_3, dd_Smed_v6_10244_0_3, [Score=549, Expect=0.0]} {RNA1509_39964, RNA1509_51119, RNA1509_8170} {RNA1310_3822, RNA1509_39964, RNA1509_51119} {RNA1509_39964, RNA1509_51119, RNA815_867}
37. MligTC455_53671 962 20.04 Mlig455_051330

Neo: -

Age: Down-Up-Down

Region-enriched R4: 2.598/0.00081

1.907 - - - - 0.938 0.969 Mlig455_051330 {REF} {Length: 1160} {Pfam: Putative Interleukin 2 receptor, gamma chain [PF15874.7, score=53.2]} {RNA1509_56185} {RNA1310_9900, RNA1509_56185} {RNA1509_56185, RNA815_3819.1}
38. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

CNTRL 1.866 - - - - 0.963 0.903

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
39. MligTC455_27638 969 20.19 Mlig455_022789

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.917

CLUAP1 1.835 - - - - 0.981 0.854 Mlig455_022789 {REF} {Length: 2458} {Pfam: Clusterin-associated protein-1 [PF10234.11, score=358.0]} {Human: ENSG00000103351, CLUAP1, clusterin associated protein 1, [RH, Score=332, Expect=1e-110]} {Mouse: ENSMUSG00000014232, Cluap1, clusterin associated protein 1, [RH, Score=330, Expect=8e-110]} {Dmel: FBgn0031196, CG17599, [RH, Score=135, Expect=1e-34]} {Celegans: WBGene00001119, dyf-3, Clusterin-associated protein 1 homolog, [RH, Score=215, Expect=1e-65]} {Smed: dd_Smed_v6_8287_0_1, dd_Smed_v6_8287_0_1, [RH, Score=333, Expect=2e-110]} {RNA1509_14292, RNA1509_25335} {RNA1310_15979, RNA1509_14292, RNA1509_25335} {RNA1509_14292, RNA1509_25335, RNA815_6417.1}
40. MligTC455_42750 7359 153.32 Mlig455_061286, Mlig455_062671

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.473

EFCAB1 1.829 - - - - 0.964 0.865

Mlig455_061286 {REF} {Length: 1260} {Pfam: EF hand [PF00036.34, score=56.6]; EF-hand domain [PF13405.8, score=55.2]; EF-hand domain pair [PF13499.8, score=51.4]; EF-hand domain pair [PF13833.8, score=46.1]; EF hand [PF13202.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=26.6]} {Human: ENSG00000034239, EFCAB1, EF-hand calcium binding domain 1, [RH, Score=187, Expect=8e-60]} {Mouse: ENSMUSG00000068617, Efcab1, EF-hand calcium binding domain 1, [RH, Score=186, Expect=1e-59]} {Dmel: FBgn0029995, CG2256, [Score=159, Expect=2e-47]} {Celegans: WBGene00003565, ncs-3, Neuronal Calcium Sensor family, [Score=66.2, Expect=2e-13]} {Smed: dd_Smed_v6_5488_0_1, dd_Smed_v6_5488_0_1, [RH, Score=243, Expect=6e-82]} {RNA1509_12780} {RNA1310_30442} {RNA815_14317}

Mlig455_062671 {REF} {Length: 1261} {Pfam: EF hand [PF00036.34, score=56.6]; EF-hand domain [PF13405.8, score=55.2]; EF-hand domain pair [PF13499.8, score=51.4]; EF-hand domain pair [PF13833.8, score=46.1]; EF hand [PF13202.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=26.6]} {Human: ENSG00000034239, EFCAB1, EF-hand calcium binding domain 1, [RH, Score=187, Expect=8e-60]} {Mouse: ENSMUSG00000068617, Efcab1, EF-hand calcium binding domain 1, [RH, Score=186, Expect=1e-59]} {Dmel: FBgn0029995, CG2256, [Score=159, Expect=2e-47]} {Celegans: WBGene00003565, ncs-3, Neuronal Calcium Sensor family, [Score=66.2, Expect=2e-13]} {Smed: dd_Smed_v6_5488_0_1, dd_Smed_v6_5488_0_1, [RH, Score=243, Expect=6e-82]} {RNA1509_12780, RNA1509_34046, RNA1509_3432, RNA1509_45202} {RNA1310_30442, RNA1509_12780, RNA1509_34046, RNA1509_3432, RNA1509_45202} {RNA1509_12780, RNA1509_34046, RNA1509_3432, RNA1509_45202, RNA815_14317}
41. MligTC455_52129 3929 81.86 Mlig455_011780, Mlig455_013012, Mlig455_013041

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.012/0.02624

CALM2 1.827 - - - - 0.975 0.852

Mlig455_011780 {REF} {Length: 754} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=60.7]; EF-hand domain pair [PF13833.8, score=47.6]; EF hand [PF00036.34, score=39.8]; EF-hand domain [PF13405.8, score=33.6]; EF-hand domain [PF14658.8, score=30.4]; EF hand [PF13202.8, score=29.3]; EF-hand domain [PF08976.13, score=20.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=136, Expect=9e-41]; ENSG00000160014, CALM3, calmodulin 3, [Score=134, Expect=3e-40]; ENSG00000198668, CALM1, calmodulin 1, [Score=134, Expect=2e-40]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=136, Expect=2e-41]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=135, Expect=2e-40]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=134, Expect=2e-40]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=134, Expect=2e-40]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=132, Expect=5e-40]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=132, Expect=3e-40]} {Smed: dd_Smed_v6_10239_0_1, dd_Smed_v6_10239_0_1, [RH, Score=138, Expect=3e-42]} {RNA1509_7925} {RNA1310_37112.2} {RNA815_24030}

Mlig455_013012 {REF} {Length: 765} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=60.7]; EF-hand domain pair [PF13833.8, score=47.6]; EF hand [PF00036.34, score=39.8]; EF-hand domain [PF13405.8, score=33.6]; EF-hand domain [PF14658.8, score=30.4]; EF hand [PF13202.8, score=29.3]; EF-hand domain [PF08976.13, score=20.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=136, Expect=9e-41]; ENSG00000160014, CALM3, calmodulin 3, [Score=134, Expect=3e-40]; ENSG00000198668, CALM1, calmodulin 1, [Score=134, Expect=2e-40]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=136, Expect=2e-41]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=135, Expect=2e-40]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=134, Expect=2e-40]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=134, Expect=2e-40]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=132, Expect=5e-40]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=132, Expect=3e-40]} {Smed: dd_Smed_v6_10239_0_1, dd_Smed_v6_10239_0_1, [RH, Score=138, Expect=3e-42]} {RNA1509_7925} {RNA1310_37112.2} {RNA815_24030}

Mlig455_013041 {REF} {Length: 786} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=60.1]; EF-hand domain pair [PF13833.8, score=47.6]; EF hand [PF00036.34, score=38.5]; EF-hand domain [PF13405.8, score=34.4]; EF-hand domain [PF14658.8, score=29.1]; EF hand [PF13202.8, score=28.7]; EF-hand domain [PF08976.13, score=20.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=136, Expect=8e-41]; ENSG00000160014, CALM3, calmodulin 3, [Score=134, Expect=3e-40]; ENSG00000198668, CALM1, calmodulin 1, [Score=134, Expect=2e-40]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=136, Expect=2e-41]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=135, Expect=2e-40]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=134, Expect=2e-40]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=134, Expect=2e-40]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=132, Expect=4e-40]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=132, Expect=3e-40]} {Smed: dd_Smed_v6_10239_0_1, dd_Smed_v6_10239_0_1, [RH, Score=137, Expect=7e-42]} {RNA1509_20533, RNA1509_7925} {RNA1310_37112.2, RNA1509_20533, RNA1509_7925} {RNA1509_20533, RNA1509_7925, RNA815_24030}
42. MligTC455_42749 3668 76.41 Mlig455_061319

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.194

EFCAB1 1.824 - - - - 0.960 0.864 Mlig455_061319 {REF} {Length: 1137} {Pfam: EF hand [PF00036.34, score=56.5]; EF-hand domain [PF13405.8, score=55.2]; EF-hand domain pair [PF13499.8, score=51.3]; EF-hand domain pair [PF13833.8, score=45.2]; EF hand [PF13202.8, score=43.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=26.6]} {Human: ENSG00000034239, EFCAB1, EF-hand calcium binding domain 1, [RH, Score=187, Expect=1e-59]} {Mouse: ENSMUSG00000068617, Efcab1, EF-hand calcium binding domain 1, [RH, Score=186, Expect=3e-59]} {Dmel: FBgn0029995, CG2256, [Score=158, Expect=4e-47]} {Celegans: WBGene00003565, ncs-3, Neuronal Calcium Sensor family, [Score=65.9, Expect=3e-13]} {Smed: dd_Smed_v6_5488_0_1, dd_Smed_v6_5488_0_1, [RH, Score=242, Expect=1e-81]} {RNA1509_12780} {RNA1310_30442} {RNA815_14317}
43. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

FLNB 1.801 - - - - 0.950 0.851

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
44. MligTC455_23214 1621 33.76 Mlig455_017615

Neo: -

Age: -

HEXA 1.8 - - - - 0.960 0.840 Mlig455_017615 {REF} {Length: 4140} {TRANSSPLICED} {Pfam: Glycosyl hydrolase family 20, catalytic domain [PF00728.24, score=248.2]; Putative carbohydrate binding domain [PF03173.15, score=52.8]} {Human: ENSG00000213614, HEXA, hexosaminidase subunit alpha, [Score=80.5, Expect=6e-15]} {Mouse: ENSMUSG00000025232, Hexa, hexosaminidase A, [Score=79.7, Expect=7e-15]} {Dmel: FBgn0041629, Hexo2, Hexosaminidase 2, [Score=79.0, Expect=1e-14]} {Celegans: WBGene00020509, hex-1, Beta-hexosaminidase A, [Score=64.3, Expect=3e-10]} {Smed: dd_Smed_v6_3964_0_2, dd_Smed_v6_3964_0_2, [Score=106, Expect=3e-23]} {RNA1509_42952} {RNA1310_2171} {RNA815_1707.1}
45. MligTC455_40794 268 5.57 Mlig455_017617

Neo: -

Age: -

1.796 - 0.836 - - 0.960 - Mlig455_017617 {REF} {Length: 2441} {TRANSSPLICED} {Pfam: RING-variant domain [PF12906.9, score=43.8]} {Dmel: FBgn0035983, CG4080, [Score=48.9, Expect=6e-06]} {RNA1509_39355} {RNA1310_22099.1} {RNA815_10655}
46. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

1.793 0.840 - - - 0.953 - Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
47. MligTC455_46080 6035 125.73 Mlig455_028154

Neo: -

Age: -

MVP 1.792 - 0.828 - - 0.964 - Mlig455_028154 {REF} {Length: 4279} {Pfam: Major Vault Protein repeat domain [PF01505.20, score=211.7]; Shoulder domain [PF11978.10, score=168.6]; Major Vault Protein repeat domain [PF17794.3, score=126.9]; Major Vault Protein Repeat domain [PF17795.3, score=121.0]; Major Vault Protein repeat domain [PF17796.3, score=105.2]} {Human: ENSG00000013364, MVP, major vault protein, [RH, Score=1070, Expect=0.0]} {Mouse: ENSMUSG00000030681, Mvp, major vault protein, [RH, Score=1066, Expect=0.0]} {Smed: dd_Smed_v6_1098_0_1, dd_Smed_v6_1098_0_1, [RH, Score=1104, Expect=0.0]} {RNA1509_12022, RNA1509_1449, RNA1509_17945, RNA1509_5740, RNA1509_7827} {RNA1310_2563.1, RNA1509_12022, RNA1509_1449, RNA1509_17945, RNA1509_5740, RNA1509_7827} {RNA1509_12022, RNA1509_1449, RNA1509_17945, RNA1509_5740, RNA1509_7827, RNA815_968.1}
48. MligTC455_49526 450 9.38 Mlig455_050949

Neo: -

Age: logFC(26M/2M)=-0.615

CALM2 1.784 - - - - 0.965 0.819 Mlig455_050949 {REF} {Length: 3680} {Pfam: EF-hand domain pair [PF13499.8, score=87.8]; EF hand [PF00036.34, score=79.8]; EF-hand domain [PF13405.8, score=67.4]; EF hand [PF13202.8, score=65.4]; EF-hand domain pair [PF13833.8, score=60.3]; EF-hand domain [PF08976.13, score=22.2]; EF-hand domain [PF14658.8, score=21.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=18.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=5e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=5e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=5e-24]; ENSG00000178363, CALML3, calmodulin like 3, [Score=99.4, Expect=8e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=103, Expect=9e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=102, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=3e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=3e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=99.0, Expect=6e-24]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=102, Expect=4e-25]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=100, Expect=1e-24]} {RNA1509_48556} {RNA1310_10152.1} {RNA815_3673.1}
49. MligTC455_46081 6090 126.87 Mlig455_028224

Neo: -

Age: -

MVP 1.781 - 0.823 - - 0.958 - Mlig455_028224 {REF} {Length: 3876} {Pfam: Major Vault Protein repeat domain [PF01505.20, score=211.9]; Major Vault Protein repeat domain [PF17794.3, score=126.9]; Major Vault Protein Repeat domain [PF17795.3, score=120.8]; Major Vault Protein repeat domain [PF17796.3, score=105.4]; Shoulder domain [PF11978.10, score=47.6]} {Human: ENSG00000013364, MVP, major vault protein, [Score=801, Expect=0.0]} {Mouse: ENSMUSG00000030681, Mvp, major vault protein, [Score=850, Expect=0.0]} {Smed: dd_Smed_v6_1098_0_1, dd_Smed_v6_1098_0_1, [Score=880, Expect=0.0]} {RNA1509_1449} {RNA1310_2563.2} {RNA815_968.1}
50. MligTC455_44679 1192 24.82 Mlig455_015484

Neo: -

Age: -

CATIP 1.78 - 0.829 - - 0.951 - Mlig455_015484 {REF} {Length: 1772} {Human: ENSG00000158428, CATIP, ciliogenesis associated TTC17 interacting protein, [RH, Score=235, Expect=2e-73]} {Mouse: ENSMUSG00000073650, Catip, ciliogenesis associated TTC17 interacting protein, [RH, Score=199, Expect=1e-58]} {Smed: dd_Smed_v6_5952_0_4, dd_Smed_v6_5952_0_4, [RH, Score=307, Expect=6e-102]} {RNA1509_4430} {RNA1310_17964} {RNA815_14802}
51. MligTC455_52249 1365 28.44 Mlig455_007872

Neo: -

Age: Down-Down-Up

Region-enriched R2: 1.111/0.04280

1.775 - 0.808 - - 0.967 - Mlig455_007872 {REF} {Length: 2081} {Pfam: Transmembrane protein 237 [PF15383.8, score=91.3]} {Mouse: ENSMUSG00000038079, Tmem237, transmembrane protein 237, [Score=55.1, Expect=1e-07]} {RNA1509_6211} {RNA1310_13658, RNA1509_6211} {RNA1509_6211, RNA815_1318.1}
52. MligTC455_20850 1618 33.71 Mlig455_021473, Mlig455_067356

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.171

MAF1 1.774 - 0.794 - - 0.980 -

Mlig455_021473 {REF} {Length: 2464} {Pfam: Maf1 regulator [PF09174.12, score=163.9]} {Human: ENSG00000179632, MAF1, MAF1 homolog, negative regulator of RNA polymerase III, [RH, Score=148, Expect=9e-43]} {Mouse: ENSMUSG00000022553, Maf1, MAF1 homolog, negative regulator of RNA polymerase III, [RH, Score=145, Expect=8e-42]} {Dmel: FBgn0267861, Maf1, [RH, Score=156, Expect=1e-46]} {Celegans: WBGene00016622, mafr-1, Repressor of RNA polymerase III transcription MAF1, [RH, Score=100, Expect=4e-25]} {RNA1509_23418, RNA1509_44779} {RNA1310_20653.1, RNA1509_44779} {RNA1509_44779, RNA815_7842.1}

Mlig455_067356 {REF} {Length: 2464} {Pfam: Maf1 regulator [PF09174.12, score=163.9]} {Human: ENSG00000179632, MAF1, MAF1 homolog, negative regulator of RNA polymerase III, [RH, Score=148, Expect=9e-43]} {Mouse: ENSMUSG00000022553, Maf1, MAF1 homolog, negative regulator of RNA polymerase III, [RH, Score=145, Expect=8e-42]} {Dmel: FBgn0267861, Maf1, [RH, Score=156, Expect=1e-46]} {Celegans: WBGene00016622, mafr-1, Repressor of RNA polymerase III transcription MAF1, [RH, Score=100, Expect=4e-25]} {RNA1509_13113, RNA1509_23418, RNA1509_24039} {RNA1310_20653.1, RNA1509_13113, RNA1509_23418, RNA1509_24039} {RNA1509_13113, RNA1509_23418, RNA1509_24039, RNA815_7842.1}
53. MligTC455_14477 676 14.08 Mlig455_030081

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.270

1.77 - - - - 0.952 0.818 Mlig455_030081 {REF} {Length: 1773} {RNA1509_4043} {RNA1310_3308.1, RNA1509_4043} {RNA1509_4043, RNA815_1039.1}
54. MligTC455_30192 1664 34.66 Mlig455_026693

Neo: -

Age: -

FOXRED2 1.767 0.789 - - - 0.978 - Mlig455_026693 {REF} {Length: 18036} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=147.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=45.8]; HI0933-like protein [PF03486.16, score=31.1]; FAD dependent oxidoreductase [PF01266.26, score=26.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=25.0]; FAD binding domain [PF01494.21, score=22.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=22.5]; Flavin containing amine oxidoreductase [PF01593.26, score=21.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=20.1]} {Human: ENSG00000100350, FOXRED2, FAD dependent oxidoreductase domain containing 2, [RH, Score=493, Expect=4e-167]} {Mouse: ENSMUSG00000016552, Foxred2, FAD-dependent oxidoreductase domain containing 2, [RH, Score=498, Expect=3e-169]} {Celegans: WBGene00001479, fmo-4, Flavin-containing monooxygenase, [Score=53.5, Expect=4e-07]} {Smed: dd_Smed_v6_12138_0_1, dd_Smed_v6_12138_0_1, [RH, Score=474, Expect=4e-161]} {RNA1509_13675, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1310_861.1, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978, RNA815_570.1}
55. MligTC455_32519 147 3.06 Mlig455_017549

Neo: -

Age: logFC(26M/2M)=-0.495

NWD2 1.767 - 0.796 - - 0.971 - Mlig455_017549 {REF} {Length: 6334} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA ATPase domain [PF13191.8, score=38.4]; NACHT domain [PF05729.14, score=34.5]; AAA domain [PF13481.8, score=20.7]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=347, Expect=8e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=340, Expect=1e-96]} {Dmel: FBgn0038397, CG10185, [Score=472, Expect=9e-143]} {Celegans: WBGene00020254, T05C3.2, [Score=527, Expect=1e-162]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=380, Expect=2e-110]} {RNA1509_23488} {RNA1310_497.1} {RNA815_237}
56. MligTC455_29374 7227 150.55 Mlig455_034712, Mlig455_067593, Mlig455_067609

Neo: -

Age: -

1.765 - - 0.805 - 0.960 -

Mlig455_034712 {REF} {Length: 2290} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}

Mlig455_067593 {REF} {Length: 2079} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}

Mlig455_067609 {REF} {Length: 2001} {RNA1509_12685, RNA1509_15903, RNA1509_3330} {RNA1310_13623.1, RNA1509_12685, RNA1509_15903} {RNA1509_12685, RNA1509_15903, RNA815_4944.1}
57. MligTC455_43338 3043 63.4 Mlig455_057398, Mlig455_059559

Neo: -

Age: logFC(26M/2M)=-0.259

Region-enriched R2: 1.086/0.00779

CYB5D1 1.764 0.809 - - - 0.955 -

Mlig455_057398 {REF} {Length: 1138} {Pfam: Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.8]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [Score=215, Expect=1e-70]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [Score=223, Expect=7e-74]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [Score=221, Expect=3e-73]} {RNA1509_11346} {RNA1310_26198} {RNA815_11579}

Mlig455_059559 {REF} {Length: 1306} {Pfam: Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=35.0]; Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.5]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [RH, Score=260, Expect=6e-88]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [RH, Score=263, Expect=2e-89]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [RH, Score=260, Expect=3e-88]} {RNA1509_5289} {RNA1310_26198, RNA1509_5289} {RNA1509_5289, RNA815_11579}
58. MligTC455_49448 237 4.94 Mlig455_057665

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.549

PRKCQ 1.741 - - 0.783 - 0.958 - Mlig455_057665 {REF} {Length: 2763} {Pfam: Protein kinase domain [PF00069.27, score=119.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=84.8]; Kinase-like [PF14531.8, score=23.9]} {Human: ENSG00000065675, PRKCQ, protein kinase C theta, [Score=90.1, Expect=1e-18]; ENSG00000067606, PRKCZ, protein kinase C zeta, [Score=89.4, Expect=2e-18]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=88.6, Expect=4e-18]; ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=88.6, Expect=4e-18]; ENSG00000163558, PRKCI, protein kinase C iota, [Score=88.2, Expect=5e-18]; ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [Score=87.8, Expect=5e-18]; ENSG00000027075, PRKCH, protein kinase C eta, [Score=85.9, Expect=2e-17]; ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=85.9, Expect=4e-17]} {Mouse: ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=88.6, Expect=3e-18]; ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=88.2, Expect=4e-18]; ENSMUSG00000021108, Prkch, protein kinase C, eta, [Score=87.8, Expect=5e-18]; ENSMUSG00000037643, Prkci, protein kinase C, iota, [Score=87.8, Expect=4e-18]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=87.8, Expect=4e-18]; ENSMUSG00000031309, Rps6ka3, ribosomal protein S6 kinase polypeptide 3, [Score=87.4, Expect=7e-18]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=84.7, Expect=6e-17]; ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=84.7, Expect=6e-17]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=84.7, Expect=6e-17]; ENSMUSG00000026778, Prkcq, protein kinase C, theta, [Score=84.3, Expect=7e-17]; ENSMUSG00000019699, Akt3, thymoma viral proto-oncogene 3, [Score=84.3, Expect=4e-17]} {Dmel: FBgn0003093, Pkc98E, Protein C kinase 98E, [Score=86.7, Expect=7e-18]} {Celegans: WBGene00004032, pkc-1, Protein kinase C-like 1B, [Score=84.7, Expect=3e-17]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=88.2, Expect=2e-18]} {RNA1509_57646} {RNA1310_18713, RNA1509_57646} {RNA1509_57646, RNA815_7871}
59. MligTC455_38015 2996 62.41 Mlig455_003768, Mlig455_003780

Neo: -

Age: Down-Down-Up

CFAP53 1.74 - - - - 0.787 0.953

Mlig455_003768 {REF} {Length: 3258} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=77.0]} {Human: ENSG00000172361, CFAP53, cilia and flagella associated protein 53, [RH, Score=172, Expect=4e-47]} {Mouse: ENSMUSG00000035394, Cfap53, cilia and flagella associated protein 53, [RH, Score=164, Expect=2e-44]} {Smed: dd_Smed_v6_3219_0_1, dd_Smed_v6_3219_0_1, [RH, Score=302, Expect=7e-97]} {RNA1509_1100, RNA1509_19749, RNA1509_56592} {RNA1310_13648, RNA1509_19749, RNA1509_56592} {RNA1509_19749, RNA1509_56592, RNA815_5728}

Mlig455_003780 {REF} {Length: 2775} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=76.3]} {Human: ENSG00000172361, CFAP53, cilia and flagella associated protein 53, [RH, Score=171, Expect=1e-46]} {Mouse: ENSMUSG00000035394, Cfap53, cilia and flagella associated protein 53, [RH, Score=166, Expect=1e-44]} {Smed: dd_Smed_v6_3219_0_1, dd_Smed_v6_3219_0_1, [RH, Score=302, Expect=9e-97]} {RNA1509_1100, RNA1509_14187} {RNA1310_13648, RNA1509_14187} {RNA1509_14187, RNA815_5728}
60. MligTC455_43992 10566 220.12 Mlig455_000729, Mlig455_000776, Mlig455_034216

Neo: -

Age: Down-Up-Up

1.73 - - - - 0.967 0.763

Mlig455_000729 {REF} {Length: 1532} {Pfam: Dynein light chain type 1 [PF01221.20, score=58.1]; EF hand [PF00036.34, score=44.8]; EF-hand domain pair [PF13499.8, score=44.6]; EF hand [PF13202.8, score=36.8]; EF-hand domain [PF13405.8, score=36.6]; EF-hand domain pair [PF13833.8, score=24.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.7]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=138, Expect=1e-41]} {RNA1509_1700} {RNA1310_32883, RNA1509_1700} {RNA1509_1700, RNA815_15215}

Mlig455_000776 {REF} {Length: 1055} {Pfam: Dynein light chain type 1 [PF01221.20, score=59.5]; EF-hand domain pair [PF13499.8, score=45.0]; EF hand [PF00036.34, score=44.8]; EF hand [PF13202.8, score=36.8]; EF-hand domain [PF13405.8, score=36.5]; EF-hand domain pair [PF13833.8, score=24.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.3]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=139, Expect=8e-42]} {RNA1509_1700, RNA1509_19296} {RNA1310_32883, RNA1509_19296} {RNA1509_19296, RNA815_15215}

Mlig455_034216 {REF} {Length: 1060} {Pfam: Dynein light chain type 1 [PF01221.20, score=59.2]; EF hand [PF00036.34, score=44.8]; EF-hand domain pair [PF13499.8, score=44.6]; EF hand [PF13202.8, score=36.8]; EF-hand domain [PF13405.8, score=36.6]; EF-hand domain pair [PF13833.8, score=24.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=23.4]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [RH, Score=139, Expect=7e-42]} {RNA1509_1700} {RNA1310_32883} {RNA815_15215}
61. MligTC455_48507 330 6.88 Mlig455_030151

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.466

TMEM232 1.728 - - - - 0.964 0.764 Mlig455_030151 {REF} {Length: 2337} {TRANSSPLICED} {Pfam: Transmembrane protein family 232 [PF15877.7, score=221.6]} {Human: ENSG00000186952, TMEM232, transmembrane protein 232, [Score=155, Expect=2e-39]} {Mouse: ENSMUSG00000045036, Tmem232, transmembrane protein 232, [Score=164, Expect=2e-42]} {Smed: dd_Smed_v6_15138_0_1, dd_Smed_v6_15138_0_1, [RH, Score=160, Expect=8e-42]} {RNA1509_11088} {RNA1310_8942.1} {RNA815_6522}
62. MligTC455_43766 2863 59.66 Mlig455_001907

Neo: -

Age: logFC(26M/2M)=-0.394

EFHB 1.725 - - 0.762 - 0.963 - Mlig455_001907 {REF} {Length: 2219} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=45.4]; EF hand [PF00036.34, score=42.6]; EF-hand domain [PF13405.8, score=40.6]; Family of unknown function (DUF5580) [PF17743.3, score=32.4]; EF hand [PF13202.8, score=31.5]; EF-hand domain pair [PF13833.8, score=19.0]} {Human: ENSG00000163576, EFHB, EF-hand domain family member B, [Score=361, Expect=9e-117]} {Mouse: ENSMUSG00000023931, Efhb, EF hand domain family, member B, [Score=332, Expect=2e-104]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=53.5, Expect=6e-08]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=52.4, Expect=8e-08]} {Smed: dd_Smed_v6_11909_0_1, dd_Smed_v6_11909_0_1, [Score=325, Expect=5e-105]} {RNA1509_2205} {RNA1310_7693, RNA1509_2205} {RNA1509_2205, RNA815_3913}
63. MligTC455_29373 3437 71.6 Mlig455_034659

Neo: -

Age: -

1.723 - - - - 0.991 0.732 Mlig455_034659 {REF} {Length: 1882} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}
64. MligTC455_53093 333 6.93 Mlig455_002441

Neo: -

Age: Down-Up-Down

Region-enriched R2: 2.548/0.03843

SOX2 1.711 - 0.745 - - 0.966 - Mlig455_002441 {REF} {Length: 2143} {Pfam: HMG (high mobility group) box [PF00505.21, score=94.8]; HMG-box domain [PF09011.12, score=43.0]; Protein of unknown function (DUF2722) [PF10846.10, score=21.2]; VIT family [PF01988.21, score=18.8]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=179, Expect=6e-54]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=179, Expect=4e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=162, Expect=1e-44]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [Score=169, Expect=7e-51]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=158, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352} {RNA815_15989}
65. MligTC455_52029 1723 35.89 Mlig455_000356

Neo: -

Age: Down-Up-Up

DLL1 1.709 - 0.752 - - 0.957 - Mlig455_000356 {REF} {Length: 2514} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=87.1]; Human growth factor-like EGF [PF12661.9, score=49.5]; Delta serrate ligand [PF01414.21, score=48.8]; Calcium-binding EGF domain [PF07645.17, score=26.3]; EGF domain [PF12947.9, score=19.4]} {Human: ENSG00000275555, DLL1, delta like canonical Notch ligand 1, [Score=171, Expect=8e-45]; ENSG00000198719, DLL1, delta like canonical Notch ligand 1, [Score=171, Expect=8e-45]; ENSG00000128917, DLL4, delta like canonical Notch ligand 4, [Score=169, Expect=2e-44]; ENSG00000134376, CRB1, crumbs 1, cell polarity complex component, [Score=167, Expect=6e-43]} {Mouse: ENSMUSG00000014773, Dll1, delta like canonical Notch ligand 1, [Score=172, Expect=2e-45]; ENSMUSG00000027276, Jag1, jagged 1, [Score=167, Expect=5e-43]; ENSMUSG00000027878, Notch2, notch 2, [Score=165, Expect=3e-42]; ENSMUSG00000027314, Dll4, delta like canonical Notch ligand 4, [Score=164, Expect=1e-42]; ENSMUSG00000035403, Crb2, crumbs family member 2, [Score=164, Expect=4e-42]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=164, Expect=4e-42]} {Dmel: FBgn0004647, N, Notch, [Score=174, Expect=1e-45]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=137, Expect=2e-33]} {Smed: dd_Smed_v6_11876_0_1, dd_Smed_v6_11876_0_1, [Score=148, Expect=4e-37]} {RNA1509_42642, RNA1509_9673} {RNA1310_6973.1, RNA1509_42642, RNA1509_9673} {RNA1509_42642, RNA1509_9673, RNA815_2635.1}
66. MligTC455_52030 1769 36.86 Mlig455_056492

Neo: -

Age: Down-Down-Up

DLL1 1.705 - 0.745 - - 0.960 - Mlig455_056492 {REF} {Length: 2332} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=71.2]; Delta serrate ligand [PF01414.21, score=49.1]; Human growth factor-like EGF [PF12661.9, score=42.6]; Calcium-binding EGF domain [PF07645.17, score=28.2]; EGF domain [PF12947.9, score=23.9]} {Human: ENSG00000198719, DLL1, delta like canonical Notch ligand 1, [Score=164, Expect=1e-42]; ENSG00000275555, DLL1, delta like canonical Notch ligand 1, [Score=164, Expect=1e-42]; ENSG00000128917, DLL4, delta like canonical Notch ligand 4, [Score=157, Expect=2e-40]} {Mouse: ENSMUSG00000014773, Dll1, delta like canonical Notch ligand 1, [Score=166, Expect=2e-43]} {Dmel: FBgn0004647, N, Notch, [Score=152, Expect=2e-38]} {Celegans: WBGene00000792, crb-1, Drosophila CRumBs homolog, [Score=126, Expect=4e-30]} {Smed: dd_Smed_v6_11876_0_1, dd_Smed_v6_11876_0_1, [Score=135, Expect=3e-33]} {RNA1509_9673} {RNA1310_6973.1} {RNA815_2635.2}
67. MligTC455_08178 288 6.01 Mlig455_062827

Neo: -

Age: Down-Up-Down

ANK2 1.702 - - - 0.744 0.958 - Mlig455_062827 {REF} {Length: 2430} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=60.2]; Ankyrin repeat [PF00023.32, score=47.3]; Ankyrin repeats (many copies) [PF13637.8, score=34.0]; Ankyrin repeats (many copies) [PF13857.8, score=33.9]; Ankyrin repeat [PF13606.8, score=31.7]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=50.8, Expect=3e-06]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=50.8, Expect=2e-06]; ENSMUSG00000047117, Ankdd1b, ankyrin repeat and death domain containing 1B, [Score=50.4, Expect=2e-06]} {Dmel: FBgn0039590, CG10011, [Score=48.1, Expect=1e-05]} {Smed: dd_Smed_v6_2072_0_26, dd_Smed_v6_2072_0_26, [Score=48.9, Expect=4e-06]} {RNA1509_10786} {RNA1310_15894} {RNA815_6009}
68. MligTC455_36043 215 4.49 Mlig455_046412

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.608

Region-enriched R4: 3.299/0.00544

LOXHD1 1.7 - - 0.748 - 0.952 - Mlig455_046412 {REF} {Length: 3070} {TRANSSPLICED} {Pfam: PLAT/LH2 domain [PF01477.25, score=52.2]} {Human: ENSG00000167210, LOXHD1, lipoxygenase homology domains 1, [Score=75.9, Expect=2e-13]} {Mouse: ENSMUSG00000032818, Loxhd1, lipoxygenase homology domains 1, [Score=76.6, Expect=5e-14]} {Smed: dd_Smed_v6_39713_0_1, dd_Smed_v6_39713_0_1, [RH, Score=81.3, Expect=4e-16]} {RNA1509_25188, RNA1509_53601} {RNA1310_11606, RNA1509_25188, RNA1509_53601} {RNA1509_25188, RNA1509_53601, RNA815_15282}
69. MligTC455_16955 1687 35.15 Mlig455_051000

Neo: -

Age: Down-Up-Up

PLA2G7 1.699 - 0.734 - - 0.965 - Mlig455_051000 {REF} {Length: 1559} {TRANSSPLICED} {Pfam: Platelet-activating factor acetylhydrolase, isoform II [PF03403.15, score=213.8]; alpha/beta hydrolase fold [PF00561.22, score=28.3]; Alpha/beta hydrolase family [PF12697.9, score=26.6]; Serine aminopeptidase, S33 [PF12146.10, score=25.3]; Chlorophyllase enzyme [PF12740.9, score=20.4]} {Human: ENSG00000146070, PLA2G7, phospholipase A2 group VII, [RH, Score=171, Expect=1e-48]} {Mouse: ENSMUSG00000037366, Pafah2, platelet-activating factor acetylhydrolase 2, [RH, Score=163, Expect=5e-46]; ENSMUSG00000023913, Pla2g7, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), [RH, Score=158, Expect=1e-43]} {Celegans: WBGene00003906, paf-1, PAF-1; PAF-acetylhydrolase, [RH, Score=142, Expect=2e-38]} {RNA1509_16678, RNA1509_21980} {RNA1310_21439.1, RNA1509_16678, RNA1509_21980} {RNA1509_16678, RNA1509_21980, RNA815_19873}
70. MligTC455_23082 1608 33.5 Mlig455_024173

Neo: -

Age: -

FAT4 1.698 - - - - 0.955 0.743 Mlig455_024173 {REF} {Length: 8284} {Pfam: Cadherin domain [PF00028.19, score=731.9]; Cadherin-like [PF16184.7, score=111.8]; Cadherin-like [PF08266.14, score=26.5]} {Human: ENSG00000196159, FAT4, FAT atypical cadherin 4, [Score=544, Expect=2e-155]} {Mouse: ENSMUSG00000046743, Fat4, FAT atypical cadherin 4, [Score=514, Expect=2e-146]} {Dmel: FBgn0284247, ds, dachsous, [Score=463, Expect=8e-131]} {Celegans: WBGene00001475, fmi-1, FlaMIngo (Cadherin plus 7TM domain) homolog; Flamingo-like protein FMI-1, [Score=276, Expect=4e-74]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=279, Expect=7e-75]} {RNA1509_848} {RNA1310_296} {RNA815_105}
71. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

GRIA2 1.695 - - - 0.706 0.989 -

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
72. MligTC455_26986 157 3.28 Mlig455_058044

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.496

1.693 - - - 0.734 0.959 - Mlig455_058044 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=51.3]; Ceramide kinase C-terminal domain [PF19280.1, score=22.6]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=55.1, Expect=2e-07]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=52.4, Expect=1e-06]} {RNA1509_33630, RNA1509_39108} {RNA1310_4577, RNA1509_33630, RNA1509_39108} {RNA1509_33630, RNA1509_39108, RNA815_1173}
73. MligTC455_31427 429 8.94 Mlig455_024101

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.449

CHRNA3 1.692 - 0.721 - - 0.971 - Mlig455_024101 {REF} {Length: 2557} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=242.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=210.4]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=395, Expect=3e-131]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=377, Expect=1e-122]} {Mouse: ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=372, Expect=8e-121]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=363, Expect=2e-119]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=355, Expect=4e-116]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=443, Expect=2e-149]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=387, Expect=2e-128]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=382, Expect=2e-126]} {RNA1509_19028} {RNA1310_8041, RNA1509_19028} {RNA1509_19028, RNA815_11178}
74. MligTC455_23582 290 6.04 Mlig455_043258

Neo: -

Age: logFC(26M/2M)=-1.253

CCDC33 1.69 - - - - 0.957 0.733 Mlig455_043258 {REF} {Length: 3463} {TRANSSPLICED} {Pfam: C2 domain [PF00168.32, score=24.6]; C-terminal membrane-localisation domain of ion-channel, VCN1 [PF16799.7, score=19.4]} {Human: ENSG00000140481, CCDC33, coiled-coil domain containing 33, [RH, Score=94.7, Expect=4e-19]} {Mouse: ENSMUSG00000037716, Ccdc33, coiled-coil domain containing 33, [RH, Score=165, Expect=3e-41]} {Smed: dd_Smed_v6_15844_0_1, dd_Smed_v6_15844_0_1, [RH, Score=195, Expect=4e-51]} {RNA1509_7141} {RNA1310_3740, RNA1509_7141} {RNA1509_7141, RNA815_780.1}
75. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

1.689 - - - - 0.953 0.736 Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
76. MligTC455_31292 287 5.97 Mlig455_059964

Neo: -

Age: logFC(26M/2M)=-0.518

1.685 - - - 0.713 0.972 - Mlig455_059964 {REF} {Length: 6272} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4549) [PF15082.8, score=142.8]; Ligand-gated ion channel [PF00060.28, score=50.1]} {Mouse: ENSMUSG00000075225, Ccdc162, coiled-coil domain containing 162, [Score=914, Expect=0.0]} {Dmel: FBgn0052704, Ir8a, Ionotropic receptor 8a, [Score=55.5, Expect=5e-07]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [Score=58.2, Expect=6e-08]} {Smed: dd_Smed_v6_16643_0_1, dd_Smed_v6_16643_0_1, [RH, Score=706, Expect=0.0]} {RNA1509_21772} {RNA1310_311.1} {RNA815_144.1}
77. MligTC455_24940 3175 66.14 Mlig455_011276, Mlig455_011374

Neo: -

Age: Down-Up-Up

1.684 - - - - 0.955 0.729

Mlig455_011276 {REF} {Length: 3380} {Pfam: Reeler domain [PF02014.18, score=50.9]; Eukaryotic cytochrome b561 [PF03188.18, score=38.4]} {Celegans: WBGene00007339, C05D12.1, [Score=68.2, Expect=9e-12]} {Smed: dd_Smed_v6_13311_0_1, dd_Smed_v6_13311_0_1, [Score=155, Expect=4e-40]} {RNA1509_34604, RNA1509_36747, RNA1509_52003, RNA1509_58766} {RNA1310_16616, RNA1509_36747, RNA1509_52003, RNA1509_58766} {RNA1509_36747, RNA1509_52003, RNA1509_58766, RNA815_3087.1}

Mlig455_011374 {REF} {Length: 4099} {Pfam: Reeler domain [PF02014.18, score=51.0]; Eukaryotic cytochrome b561 [PF03188.18, score=38.1]} {Celegans: WBGene00007339, C05D12.1, [Score=68.2, Expect=8e-12]} {Smed: dd_Smed_v6_13311_0_1, dd_Smed_v6_13311_0_1, [Score=153, Expect=2e-39]} {RNA1509_25592, RNA1509_34604, RNA1509_41623, RNA1509_55699} {RNA1310_16616, RNA1509_25592, RNA1509_34604, RNA1509_41623, RNA1509_55699} {RNA1509_25592, RNA1509_34604, RNA1509_41623, RNA1509_55699, RNA815_3087.1}
78. MligTC455_47210 4891 101.89 Mlig455_018786, Mlig455_048136

Neo: -

Age: logFC(26M/2M)=-0.613

1.679 - - - - 0.962 0.717

Mlig455_018786 {REF} {Length: 1388} {RNA1509_2043} {RNA1310_23078} {RNA815_8099.1}

Mlig455_048136 {REF} {Length: 1380} {RNA1509_2043} {RNA1310_23078} {RNA815_8099.1}
79. MligTC455_22765 1243 25.9 Mlig455_043090

Neo: -

Age: logFC(26M/2M)=0.341

ELOVL4 1.671 - - - - 0.953 0.718 Mlig455_043090 {REF} {Length: 2896} {TRANSSPLICED} {Pfam: GNS1/SUR4 family [PF01151.20, score=220.9]} {Human: ENSG00000118402, ELOVL4, ELOVL fatty acid elongase 4, [RH, Score=323, Expect=1e-110]} {Mouse: ENSMUSG00000032262, Elovl4, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4, [RH, Score=317, Expect=2e-108]} {Dmel: FBgn0052072, Elo68alpha, Elongase 68alpha, [RH, Score=219, Expect=9e-71]} {Celegans: WBGene00001245, elo-7, Elongation of very long chain fatty acids protein, [Score=80.5, Expect=3e-17]} {Smed: dd_Smed_v6_7835_0_1, dd_Smed_v6_7835_0_1, [RH, Score=358, Expect=3e-125]} {RNA1509_33854} {RNA1310_6579.1, RNA1509_33854} {RNA1509_33854, RNA815_7910}
80. MligTC455_27391 400 8.33 Mlig455_025302

Neo: -

Age: -

1.669 - 0.719 - - 0.950 - Mlig455_025302 {REF} {Length: 5004} {RNA1509_12762} {RNA1310_3434.1} {RNA815_1693}
81. MligTC455_37539 1140 23.75 Mlig455_046009

Neo: -

Age: Up-Down-Down

1.663 - - - 0.705 0.958 - Mlig455_046009 {REF} {Length: 2802} {RNA1509_42843} {RNA1310_13416, RNA1509_42843} {RNA1509_42843, RNA815_14162}
82. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

VASH2 0.986 - - - - 0.986 - Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
83. MligTC455_34564 216 4.51 Mlig455_045027

Neo: -

Age: -

VASH1 0.985 - - - - 0.985 - Mlig455_045027 {REF} {Length: 1457} {Pfam: Vasohibin [PF14822.8, score=320.1]} {Human: ENSG00000071246, VASH1, vasohibin 1, [RH, Score=258, Expect=2e-83]; ENSG00000143494, VASH2, vasohibin 2, [RH, Score=256, Expect=7e-83]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=261, Expect=7e-85]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=254, Expect=2e-82]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=233, Expect=4e-75]} {RNA1509_59274} {RNA1310_23626.1} {RNA815_21188.1}
84. MligTC455_30234 668 13.92 Mlig455_013688, Mlig455_020164, Mlig455_028077, Mlig455_036489, Mlig455_038238, Mlig455_049777, Mlig455_054410, Mlig455_055118, Mlig455_061417, Mlig455_068974, Mlig455_070511

Neo: -

Age: Up-Down-Down

PIF1 0.98 - - - - 0.980 -

Mlig455_013688 {REF} {Length: 3931} {Pfam: PIF1-like helicase [PF05970.16, score=335.0]; AAA domain [PF13604.8, score=47.7]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=1e-149]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=5e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_020164 {REF} {Length: 6683} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; AAA domain [PF13604.8, score=47.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.2]; AAA domain [PF13245.8, score=19.4]; Helicase [PF02689.16, score=16.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=3e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=5e-150]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_6950, RNA1509_5036} {RNA1509_5036, RNA815_356.1}

Mlig455_028077 {REF} {Length: 5927} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=333.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.6]; AAA domain [PF13604.8, score=45.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.1]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=121, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=3e-28]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=737, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_036489 {REF} {Length: 6279} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=335.1]; AAA domain [PF13604.8, score=47.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=6e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=509, Expect=7e-161]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_038238 {REF} {Length: 7170} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.3]; AAA domain [PF13604.8, score=44.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.2]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=8e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=8e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=121, Expect=1e-27]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=736, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_049777 {REF} {Length: 6866} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=175.0]; AAA domain [PF13604.8, score=43.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=123, Expect=8e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=117, Expect=2e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=120, Expect=2e-27]} {Celegans: WBGene00019136, F59H6.5, [Score=760, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=1e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_054410 {REF} {Length: 3239} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=52.6]} {Celegans: WBGene00022692, ZK250.9, [Score=162, Expect=8e-44]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=45.1, Expect=8e-06]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_055118 {REF} {Length: 6779} {Pfam: PIF1-like helicase [PF05970.16, score=330.1]; Helitron helicase-like domain at N-terminus [PF14214.8, score=169.5]; AAA domain [PF13604.8, score=47.3]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=5e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=118, Expect=7e-27]} {Celegans: WBGene00018020, F33H12.6, [Score=733, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=113, Expect=2e-25]} {RNA1509_5036} {RNA1310_6950} {RNA815_356.1}

Mlig455_061417 {REF} {Length: 5410} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=169.0]; PIF1-like helicase [PF05970.16, score=56.8]; AAA domain [PF13604.8, score=20.6]} {Celegans: WBGene00019136, F59H6.5, [Score=540, Expect=1e-169]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=70.5, Expect=4e-14]} {RNA1509_5036} {RNA1310_11485} {RNA815_356.1}

Mlig455_068974 {REF} {Length: 6598} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.8]; AAA domain [PF13604.8, score=46.0]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=127, Expect=5e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=3e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=2e-28]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_070511 {REF} {Length: 6556} {Pfam: PIF1-like helicase [PF05970.16, score=335.6]; AAA domain [PF13604.8, score=48.1]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.5]; AAA domain [PF13245.8, score=19.7]; Helicase [PF02689.16, score=16.9]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=4e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=119, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=391, Expect=6e-119]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=3e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
85. MligTC455_48348 938 19.55 Mlig455_027793, Mlig455_063494

Neo: -

Age: logFC(26M/2M)=-0.661

Region-enriched R8: 1.890/0.04247

SCN5A 0.977 - - - - 0.977 -

Mlig455_027793 {REF} {Length: 6955} {Pfam: Ion transport protein [PF00520.33, score=754.1]; Polycystin cation channel [PF08016.14, score=55.1]; ZIP Zinc transporter [PF02535.24, score=22.9]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=22.8]} {Human: ENSG00000183873, SCN5A, sodium voltage-gated channel alpha subunit 5, [RH, Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000032511, Scn5a, sodium channel, voltage-gated, type V, alpha, [Score=1260, Expect=0.0]; ENSMUSG00000001027, Scn4a, sodium channel, voltage-gated, type IV, alpha, [Score=1253, Expect=0.0]} {Dmel: FBgn0285944, para, paralytic, [Score=914, Expect=0.0]} {Celegans: WBGene00000367, cca-1, Voltage-dependent T-type calcium channel subunit alpha, [Score=452, Expect=2e-130]} {Smed: dd_Smed_v6_12243_0_1, dd_Smed_v6_12243_0_1, [RH, Score=1245, Expect=0.0]} {RNA1509_2331} {RNA1310_490.1} {RNA815_185.1}

Mlig455_063494 {REF} {Length: 7000} {Pfam: Ion transport protein [PF00520.33, score=755.0]; Polycystin cation channel [PF08016.14, score=55.6]; ZIP Zinc transporter [PF02535.24, score=23.8]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=22.8]} {Human: ENSG00000183873, SCN5A, sodium voltage-gated channel alpha subunit 5, [RH, Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000032511, Scn5a, sodium channel, voltage-gated, type V, alpha, [Score=1261, Expect=0.0]; ENSMUSG00000001027, Scn4a, sodium channel, voltage-gated, type IV, alpha, [Score=1240, Expect=0.0]} {Dmel: FBgn0285944, para, paralytic, [Score=914, Expect=0.0]} {Celegans: WBGene00001187, egl-19, Voltage-dependent L-type calcium channel subunit alpha, [Score=310, Expect=8e-85]} {Smed: dd_Smed_v6_12243_0_1, dd_Smed_v6_12243_0_1, [RH, Score=1244, Expect=0.0]} {RNA1509_2331} {RNA1310_490.1, RNA1509_2331} {RNA1509_2331, RNA815_185.1}
86. MligTC455_50432 2499 52.06 Mlig455_053597

Neo: -

Age: -

Region-enriched R8: 1.161/0.01787

ANKRD24 0.977 - - - - 0.977 - Mlig455_053597 {REF} {Length: 2565} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=56.7]; Ankyrin repeats (3 copies) [PF12796.9, score=56.0]; Ankyrin repeats (many copies) [PF13857.8, score=51.0]; Ankyrin repeat [PF00023.32, score=32.1]; Ankyrin repeat [PF13606.8, score=25.0]} {Human: ENSG00000089847, ANKRD24, ankyrin repeat domain 24, [Score=59.3, Expect=1e-08]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=59.3, Expect=5e-09]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=58.9, Expect=6e-09]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=58.9, Expect=7e-09]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=58.2, Expect=1e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=58.2, Expect=1e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=54.7, Expect=3e-07]} {Celegans: WBGene00006490, kdin-1, KiDINs220 (Vertebrate scaffold protein) homolog, [Score=50.8, Expect=2e-06]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=55.8, Expect=5e-08]} {RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000} {RNA1310_25280, RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000} {RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000, RNA815_12634}
87. MligTC455_15782 201 4.19 Mlig455_006365

Neo: -

Age: -

0.975 - - - - 0.975 - Mlig455_006365 {REF} {Length: 906} {NoTransDecoderORF} {RNA1310_47212.1} {RNA815_23096}
88. MligTC455_21470 491 10.23 Mlig455_028994

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

KCNMA1 0.973 - - - - 0.973 - Mlig455_028994 {REF} {Length: 4059} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=82.1]; Ion channel [PF07885.18, score=48.7]; Ion transport protein [PF00520.33, score=31.6]; TrkA-N domain [PF02254.20, score=27.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=484, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=482, Expect=5e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=479, Expect=1e-150]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=461, Expect=5e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=490, Expect=3e-155]} {RNA1509_10617} {RNA1310_2480.1} {RNA815_984.1}
89. MligTC455_33364 348 7.24 Mlig455_009410, Mlig455_016109, Mlig455_026502, Mlig455_027903, Mlig455_036913, Mlig455_066713, Mlig455_068644, Mlig455_070501

Neo: -

Age: logFC(26M/2M)=-0.641

NYNRIN 0.973 - - - - 0.973 -

Mlig455_009410 {REF} {Length: 6826} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=304.8]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=92.4, Expect=4e-20]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=209, Expect=1e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=301, Expect=1e-97]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_016109 {REF} {Length: 3482} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.5]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.8]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=55.7]; Aspartyl protease [PF13650.8, score=21.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=7e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=124, Expect=4e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=425, Expect=7e-131]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}

Mlig455_026502 {REF} {Length: 698} {Pfam: Zinc knuckle [PF00098.25, score=27.8]} {RNA1509_38652} {RNA1310_25149.1} {RNA815_13280}

Mlig455_027903 {REF} {Length: 3748} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.7]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=51.2]; Aspartyl protease [PF13650.8, score=21.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=121, Expect=5e-27]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=122, Expect=1e-27]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=432, Expect=8e-134]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_036913 {REF} {Length: 639} {RNA1509_48973} {RNA1310_39833} {RNA815_36286}

Mlig455_066713 {REF} {Length: 2873} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=122.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.1]; Integrase zinc binding domain [PF17921.3, score=77.1]; Integrase core domain [PF00665.28, score=53.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=117, Expect=3e-26]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=117, Expect=4e-26]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=237, Expect=1e-65]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_068644 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.2]; Integrase zinc binding domain [PF17921.3, score=79.7]; Integrase core domain [PF00665.28, score=49.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=130, Expect=4e-30]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=6e-29]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=313, Expect=5e-93]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_070501 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=123.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.2]; Integrase zinc binding domain [PF17921.3, score=76.5]; Integrase core domain [PF00665.28, score=54.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=2e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=1e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=322, Expect=2e-96]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}
90. MligTC455_38072 222 4.62 Mlig455_012098, Mlig455_023289, Mlig455_023290, Mlig455_030139

Neo: -

Age: -

0.972 - - - - 0.972 -

Mlig455_012098 {REF} {Length: 3878} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_023289 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_57501} {RNA1310_60087} {RNA815_63886}

Mlig455_023290 {REF} {Length: 660} {RNA1509_44389} {RNA1310_27455} {RNA815_10592}

Mlig455_030139 {REF} {Length: 465} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
91. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

MX2 0.972 - - - - 0.972 - Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
92. MligTC455_22397 123 2.55 Mlig455_007094, Mlig455_008909, Mlig455_015478, Mlig455_016547, Mlig455_037908, Mlig455_038997, Mlig455_051315

Neo: -

Age: -

0.971 - - - - 0.971 -

Mlig455_007094 {REF} {Length: 1370} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_008909 {REF} {Length: 529} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_015478 {REF} {Length: 1396} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_016547 {REF} {Length: 518} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_037908 {REF} {Length: 4536} {RNA1509_32371} {RNA1310_7877} {RNA815_19983}

Mlig455_038997 {REF} {Length: 520} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_051315 {REF} {Length: 240} {NoTransDecoderORF} {RNA1509_51049} {RNA1310_28962.1} {RNA815_23816.2}
93. MligTC455_31446 1599 33.32 Mlig455_068361

Neo: -

Age: logFC(26M/2M)=-0.373

0.971 - - - 0.971 - - Mlig455_068361 {REF} {Length: 2059} {Pfam: Testis-expressed sequence 33 protein family [PF15400.8, score=59.8]} {RNA1509_14252, RNA1509_53522, RNA1509_58303} {RNA1310_18609, RNA1509_14252, RNA1509_53522, RNA1509_58303} {RNA1509_14252, RNA1509_53522, RNA1509_58303, RNA815_8953.1}
94. MligTC455_28794 33 0.68 Mlig455_043620, Mlig455_043652

Neo: Irradiation

Age: Up-Down-Down

0.97 - - - - 0.970 -

Mlig455_043620 {REF} {Length: 1703} {Pfam: Tetraspanin family [PF00335.22, score=51.7]} {Smed: dd_Smed_v6_1719_0_2, dd_Smed_v6_1719_0_2, [Score=50.8, Expect=4e-07]} {RNA1509_14599} {RNA1310_20055.2} {RNA815_15207}

Mlig455_043652 {REF} {Length: 915} {TRANSSPLICED} {Pfam: Tetraspanin family [PF00335.22, score=49.3]} {Smed: dd_Smed_v6_1719_0_2, dd_Smed_v6_1719_0_2, [Score=48.5, Expect=6e-07]} {RNA1509_14599} {RNA1310_20055.2} {RNA815_15207}
95. MligTC455_34852 681 14.19 Mlig455_040753, Mlig455_066786

Neo: -

Age: logFC(26M/2M)=-0.406

CAPN3, CAPN9 0.969 - - - - 0.969 -

Mlig455_040753 {REF} {Length: 2907} {Pfam: Calpain family cysteine protease [PF00648.23, score=389.3]; Calpain large subunit, domain III [PF01067.24, score=132.2]; EF hand [PF00036.34, score=31.5]; EF-hand domain pair [PF13833.8, score=24.3]; EF-hand domain [PF13405.8, score=23.5]} {Human: ENSG00000135773, CAPN9, calpain 9, [Score=541, Expect=0.0]; ENSG00000092529, CAPN3, calpain 3, [Score=540, Expect=0.0]} {Mouse: ENSMUSG00000079110, Capn3, calpain 3, [Score=534, Expect=0.0]; ENSMUSG00000031981, Capn9, calpain 9, [Score=525, Expect=1e-177]} {Dmel: FBgn0025866, CalpB, Calpain-B, [Score=566, Expect=0.0]} {Celegans: WBGene00000542, clp-1, Calpain clp-1, [Score=436, Expect=8e-143]} {Smed: dd_Smed_v6_1752_0_4, dd_Smed_v6_1752_0_4, [Score=724, Expect=0.0]} {RNA1509_45636} {RNA1310_9182} {RNA815_3486}

Mlig455_066786 {REF} {Length: 4477} {Pfam: Calpain family cysteine protease [PF00648.23, score=389.2]; Calpain large subunit, domain III [PF01067.24, score=132.2]; EF hand [PF00036.34, score=32.0]; EF-hand domain pair [PF13833.8, score=23.4]; EF-hand domain [PF13405.8, score=23.2]; EF hand [PF13202.8, score=18.8]} {Human: ENSG00000092529, CAPN3, calpain 3, [Score=542, Expect=0.0]; ENSG00000135773, CAPN9, calpain 9, [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000079110, Capn3, calpain 3, [Score=536, Expect=0.0]; ENSMUSG00000031981, Capn9, calpain 9, [Score=526, Expect=5e-178]} {Dmel: FBgn0025866, CalpB, Calpain-B, [Score=565, Expect=0.0]} {Celegans: WBGene00000542, clp-1, Calpain clp-1, [Score=436, Expect=2e-142]} {Smed: dd_Smed_v6_1752_0_2, dd_Smed_v6_1752_0_2, [Score=724, Expect=0.0]} {RNA1509_45636} {RNA1310_9182} {RNA815_3486}
96. MligTC455_22184 57 1.18 Mlig455_011505

Neo: -

Age: -

0.968 - - - - 0.968 - Mlig455_011505 {REF} {Length: 715} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=39.4]} {RNA1509_13072} {RNA1310_4523} {RNA815_50872}
97. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

DST 0.968 - - - - 0.968 - Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}
98. MligTC455_28770 76 1.57 Mlig455_038434, Mlig455_069042

Neo: -

Age: -

0.967 - - - - 0.967 -

Mlig455_038434 {REF} {Length: 2508} {RNA1509_2515} {RNA1310_5479.1} {RNA815_3258.1}

Mlig455_069042 {REF} {Length: 1211} {NoTransDecoderORF} {RNA1509_22369, RNA1509_2515} {RNA1310_23566, RNA1509_22369} {RNA1509_22369, RNA815_3258.1}
99. MligTC455_03200 31 0.64 Mlig455_054002

Neo: -

Age: -

0.966 - - - - 0.966 - Mlig455_054002 {REF} {Length: 511} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=52.8, Expect=9e-09]} {RNA1509_8360} {RNA1310_8325.1} {RNA815_1671.1}
100. MligTC455_23078 287 5.98 Mlig455_011747

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.620

CUBN 0.966 - - - - 0.966 - Mlig455_011747 {REF} {Length: 2191} {Pfam: EGF-like domain [PF00008.29, score=33.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=52.4, Expect=2e-07]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=53.9, Expect=3e-08]} {RNA1509_38266} {RNA1310_23149} {RNA815_9585.1}

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