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Results for MligTC455_23078

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_23078 287 5.98 Mlig455_011747

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.620

CUBN Mlig455_011747 {REF} {Length: 2191} {Pfam: EGF-like domain [PF00008.29, score=33.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=52.4, Expect=2e-07]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=53.9, Expect=3e-08]} {RNA1509_38266} {RNA1310_23149} {RNA815_9585.1}

Cumulative graph for MligTC455_23078

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.551 3.025 0.21815 0.86041
RegionR2 1.844 3.025 0.06263 0.30202
RegionR3 0.212 3.025 0.76693 1.00000
RegionR4 -0.247 3.025 0.91766 1.00000
RegionR5 -0.902 3.025 0.98358 1.00000
RegionR6 0.256 3.025 0.74755 1.00000
RegionR7 1.905 3.025 0.03412 0.35164
RegionR8 2.483 3.025 0.01595 0.24570

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.275 3.025 0.99991 1.00000
RegenerationR2 -1.068 3.025 0.08703 0.47373
RegenerationR3 -0.903 3.025 0.22838 0.66337
RegenerationR4 -1.291 3.025 0.08101 0.45058
RegenerationR5 -1.291 3.025 0.08926 0.45965
RegenerationR6 -1.995 3.025 0.01516 0.15182
RegenerationBL -1.405 3.025 0.09873 0.36916
RegenerationTP -2.878 3.025 0.00219 0.07582


Genes with expression patterns similar to MligTC455_23078

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_23078 287 5.98 Mlig455_011747

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.620

CUBN 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_011747 {REF} {Length: 2191} {Pfam: EGF-like domain [PF00008.29, score=33.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=52.4, Expect=2e-07]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=53.9, Expect=3e-08]} {RNA1509_38266} {RNA1310_23149} {RNA815_9585.1}
2. MligTC455_13942 192 4 Mlig455_015587

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.561

SYT14 3.521 - - 0.780 0.861 0.916 0.964 Mlig455_015587 {REF} {Length: 3362} {Pfam: C2 domain [PF00168.32, score=38.6]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [Score=133, Expect=5e-32]; ENSG00000139973, SYT16, synaptotagmin 16, [Score=129, Expect=2e-30]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=134, Expect=8e-32]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [Score=108, Expect=3e-24]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [Score=136, Expect=2e-34]} {RNA1509_12596} {RNA1310_670.1, RNA1509_12596} {RNA1509_12596, RNA815_7240.1}
3. MligTC455_06090 223 4.65 Mlig455_037743

Neo: -

Age: Down-Up-Up

3.405 0.912 - 0.959 0.788 0.746 - Mlig455_037743 {REF} {Length: 1087} {RNA1509_10108} {RNA1310_12853.1} {RNA815_29647}
4. MligTC455_33808 22456 467.83 Mlig455_061945

Neo: -

Age: -

MOXD1 2.618 - - 0.778 - 0.884 0.956 Mlig455_061945 {REF} {Length: 2202} {TRANSSPLICED} {Pfam: Copper type II ascorbate-dependent monooxygenase, N-terminal domain [PF01082.22, score=92.1]; Copper type II ascorbate-dependent monooxygenase, C-terminal domain [PF03712.17, score=68.1]} {Human: ENSG00000079931, MOXD1, monooxygenase DBH like 1, [Score=120, Expect=5e-28]; ENSG00000123454, DBH, dopamine beta-hydroxylase, [Score=117, Expect=7e-27]} {Mouse: ENSMUSG00000020000, Moxd1, monooxygenase, DBH-like 1, [Score=135, Expect=5e-33]} {Dmel: FBgn0010329, Tbh, Tyramine beta hydroxylase, [Score=127, Expect=1e-30]} {Celegans: WBGene00006541, tbh-1, Tyramine beta-hydroxylase, [Score=139, Expect=7e-35]} {Smed: dd_Smed_v6_42610_0_1, dd_Smed_v6_42610_0_1, [Score=118, Expect=8e-29]} {RNA1509_127} {RNA1310_11166.1} {RNA815_4383.1}
5. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

DST 2.607 0.802 - 0.829 - 0.976 - Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}
6. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

XRRA1 2.57 0.772 - - 0.825 0.973 - Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
7. MligTC455_46168 633 13.18 Mlig455_016182

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.686

RIPK4 2.568 0.796 - - 0.815 0.957 - Mlig455_016182 {REF} {Length: 2089} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=70.7]; Ankyrin repeats (many copies) [PF13637.8, score=64.8]; Ankyrin repeat [PF13606.8, score=56.9]; Ankyrin repeats (many copies) [PF13857.8, score=51.0]; Ankyrin repeat [PF00023.32, score=50.6]} {Human: ENSG00000183421, RIPK4, receptor interacting serine/threonine kinase 4, [Score=69.7, Expect=9e-12]} {Mouse: ENSMUSG00000005251, Ripk4, receptor-interacting serine-threonine kinase 4, [Score=65.9, Expect=8e-11]; ENSMUSG00000040183, Ankrd6, ankyrin repeat domain 6, [Score=64.3, Expect=2e-10]} {Dmel: FBgn0039590, CG10011, [Score=57.8, Expect=3e-08]} {Smed: dd_Smed_v6_14278_0_1, dd_Smed_v6_14278_0_1, [RH, Score=97.4, Expect=7e-22]} {RNA1509_22389, RNA1509_49493} {RNA1310_14320.1, RNA1509_22389, RNA1509_49493} {RNA1509_22389, RNA1509_49493, RNA815_8642}
8. MligTC455_53853 563 11.74 Mlig455_016298

Neo: -

Age: logFC(26M/2M)=-0.225

KIDINS220 2.568 - - 0.836 - 0.766 0.966 Mlig455_016298 {REF} {Length: 5886} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=173.0]; Ankyrin repeats (many copies) [PF13857.8, score=78.1]; Ankyrin repeats (many copies) [PF13637.8, score=76.0]; Ankyrin repeat [PF13606.8, score=68.2]; Ankyrin repeat [PF00023.32, score=60.7]; Caspase domain [PF00656.24, score=55.9]; Mab-21 protein [PF03281.16, score=40.6]} {Human: ENSG00000134313, KIDINS220, kinase D interacting substrate 220, [Score=85.1, Expect=9e-16]} {Mouse: ENSMUSG00000036333, Kidins220, kinase D-interacting substrate 220, [Score=84.7, Expect=8e-16]} {Dmel: FBgn0039590, CG10011, [Score=74.7, Expect=6e-13]} {Celegans: WBGene00006490, kdin-1, KiDINs220 (Vertebrate scaffold protein) homolog, [Score=81.6, Expect=3e-15]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=68.9, Expect=2e-11]} {RNA1509_59871, RNA1509_7214} {RNA1310_1541, RNA1509_59871, RNA1509_7214} {RNA1509_59871, RNA1509_7214, RNA815_372}
9. MligTC455_39515 27644 575.93 Mlig455_031388

Neo: -

Age: -

CAV3 2.552 - - 0.782 - 0.817 0.953 Mlig455_031388 {REF} {Length: 1882} {Pfam: Caveolin [PF01146.19, score=124.4]} {Human: ENSG00000182533, CAV3, caveolin 3, [Score=94.4, Expect=5e-25]} {Mouse: ENSMUSG00000000058, Cav2, caveolin 2, [RH, Score=92.4, Expect=2e-24]} {Celegans: WBGene00000302, cav-2, Caveolin-2, [RH, Score=73.9, Expect=2e-17]} {Smed: dd_Smed_v6_877_0_1, dd_Smed_v6_877_0_1, [RH, Score=127, Expect=1e-38]} {RNA1509_1284, RNA1509_15662, RNA1509_257} {RNA1310_50452, RNA1509_1284, RNA1509_15662, RNA1509_257} {RNA1509_1284, RNA1509_15662, RNA1509_257, RNA815_18477}
10. MligTC455_14604 21 0.43 Mlig455_014269

Neo: -

Age: -

2.544 - - - 0.807 0.774 0.963 Mlig455_014269 {REF} {Length: 2720} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=90.5]} {Dmel: FBgn0022382, Pka-R2, Protein kinase, cAMP-dependent, regulatory subunit type 2, [Score=53.1, Expect=2e-07]} {Smed: dd_Smed_v6_14355_0_1, dd_Smed_v6_14355_0_1, [Score=108, Expect=3e-25]} {RNA1310_19428.1} {RNA815_22602}
11. MligTC455_26986 157 3.28 Mlig455_058044

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.496

2.542 - - 0.779 0.787 0.976 - Mlig455_058044 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=51.3]; Ceramide kinase C-terminal domain [PF19280.1, score=22.6]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=55.1, Expect=2e-07]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=52.4, Expect=1e-06]} {RNA1509_33630, RNA1509_39108} {RNA1310_4577, RNA1509_33630, RNA1509_39108} {RNA1509_33630, RNA1509_39108, RNA815_1173}
12. MligTC455_16167 177 3.69 Mlig455_065707

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.428

Region-enriched R2: 4.313/0.00011

B3GALT5 2.529 - - - 0.764 0.980 0.785 Mlig455_065707 {REF} {Length: 4598} {Pfam: Galactosyltransferase [PF01762.23, score=160.3]} {Human: ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=130, Expect=2e-33]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [Score=115, Expect=4e-28]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [Score=111, Expect=9e-27]} {Dmel: FBgn0035558, CG11357, [RH, Score=148, Expect=4e-39]} {Celegans: WBGene00000270, bre-5, Beta-1,3-galactosyltransferase bre-5, [Score=67.0, Expect=5e-12]} {Smed: dd_Smed_v6_12783_0_1, dd_Smed_v6_12783_0_1, [Score=152, Expect=6e-42]} {RNA1509_45540} {RNA1310_2435} {RNA815_25407}
13. MligTC455_44444 123 2.57 Mlig455_062758

Neo: -

Age: -

2.516 - - 0.754 - 0.795 0.967 Mlig455_062758 {REF} {Length: 1304} {Pfam: Retinal tissue protein [PF10044.11, score=28.1]} {RNA1509_3524} {RNA1310_10649.1} {RNA815_4708.1}
14. MligTC455_33106 458 9.53 Mlig455_010260

Neo: -

Age: -

DYRK2 2.503 - - - 0.791 0.952 0.760 Mlig455_010260 {REF} {Length: 4138} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=195.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=81.1]; ABC1 atypical kinase-like domain [PF03109.18, score=27.3]; Phosphotransferase enzyme family [PF01636.25, score=21.3]} {Human: ENSG00000127334, DYRK2, dual specificity tyrosine phosphorylation regulated kinase 2, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000028630, Dyrk2, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2, [RH, Score=649, Expect=0.0]} {Dmel: FBgn0027101, Dyrk3, Dual-specificity tyrosine phosphorylation-regulated kinase 3, [RH, Score=569, Expect=0.0]} {Celegans: WBGene00003150, mbk-2, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2, [RH, Score=587, Expect=0.0]} {Smed: dd_Smed_v6_10966_0_1, dd_Smed_v6_10966_0_1, [RH, Score=630, Expect=0.0]} {RNA1509_6870} {RNA1310_14641} {RNA815_4815}
15. MligTC455_43627 1683 35.07 Mlig455_012966

Neo: -

Age: -

2.488 - - - 0.748 0.970 0.770 Mlig455_012966 {REF} {Length: 4640} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=231.1]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=2e-13]} {RNA1509_10570} {RNA1310_7155.1} {RNA815_1910.1}
16. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

MAPK15 2.482 0.797 - 0.706 - 0.979 -

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
17. MligTC455_44443 3132 65.25 Mlig455_062757

Neo: -

Age: Up-Down-Down

2.475 - - 0.759 - 0.763 0.953 Mlig455_062757 {REF} {Length: 897} {RNA1509_42258} {RNA1310_10649.1} {RNA815_4791.1}
18. MligTC455_33573 324 6.75 Mlig455_021827

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.408

1.897 - - - - 0.924 0.973 Mlig455_021827 {REF} {Length: 7896} {TRANSSPLICED} {Mouse: ENSMUSG00000031727, Pmfbp1, polyamine modulated factor 1 binding protein 1, [RH, Score=56.6, Expect=4e-07]} {Smed: dd_Smed_v6_3146_0_1, dd_Smed_v6_3146_0_1, [RH, Score=184, Expect=2e-46]} {RNA1509_4189} {RNA1310_374.1} {RNA815_284}
19. MligTC455_16051 3672 76.49 Mlig455_051486

Neo: -

Age: Down-Down-Up

NUDT9 1.891 - - - - 0.967 0.924 Mlig455_051486 {REF} {Length: 1822} {TRANSSPLICED} {Pfam: NUDIX domain [PF00293.30, score=22.9]} {Human: ENSG00000170502, NUDT9, nudix hydrolase 9, [RH, Score=278, Expect=8e-92]} {Mouse: ENSMUSG00000029310, Nudt9, nudix (nucleoside diphosphate linked moiety X)-type motif 9, [RH, Score=281, Expect=4e-93]} {Dmel: FBgn0036648, CG4098, [RH, Score=258, Expect=1e-84]} {Celegans: WBGene00003583, ndx-6, Putative nudix hydrolase 6, [RH, Score=214, Expect=2e-68]} {Smed: dd_Smed_v6_1143_0_1, dd_Smed_v6_1143_0_1, [RH, Score=293, Expect=1e-98]} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_4802, RNA1509_51897} {RNA1310_32536, RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897, RNA815_11473.1}
20. MligTC455_54194 156 3.25 Mlig455_066828

Neo: -

Age: logFC(26M/2M)=-0.485

1.887 - - - - 0.907 0.980 Mlig455_066828 {REF} {Length: 1460} {RNA1509_54236} {RNA1310_18757.1, RNA1509_54236} {RNA1509_54236, RNA815_5768.1}
21. MligTC455_10416 765 15.93 Mlig455_008958

Neo: -

Age: -

Region-enriched R8: 1.474/0.04842

1.858 - - - - 0.881 0.977 Mlig455_008958 {REF} {Length: 515} {NoTransDecoderORF} {RNA1310_120997} {RNA815_53530}
22. MligTC455_33352 264 5.49 Mlig455_054858

Neo: -

Age: Down-Down-Up

1.83 - - 0.879 - - 0.951 Mlig455_054858 {REF} {Length: 672} {NoTransDecoderORF} {RNA1509_55519, RNA1509_6900} {RNA1310_4649, RNA1509_55519} {RNA1509_55519, RNA815_41852}
23. MligTC455_50996 449 9.36 Mlig455_002019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.319

Region-enriched R2: 1.520/0.04245

TRIM71 1.822 - - - 0.860 0.962 - Mlig455_002019 {REF} {Length: 2281} {Pfam: NHL repeat [PF01436.23, score=74.6]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=79.3, Expect=3e-15]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=76.3, Expect=3e-14]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=79.7, Expect=2e-15]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=76.3, Expect=2e-14]} {Dmel: FBgn0265356, tn, thin, [Score=94.0, Expect=3e-20]} {Celegans: WBGene00003026, lin-41, [Score=80.5, Expect=5e-16]} {Smed: dd_Smed_v6_13659_0_1, dd_Smed_v6_13659_0_1, [RH, Score=102, Expect=2e-24]} {RNA1509_17378} {RNA1310_19512.1, RNA1509_17378} {RNA1509_17378, RNA815_7968}
24. MligTC455_12684 278 5.79 Mlig455_016753

Neo: -

Age: -

CACNA1C 1.818 - - - 0.857 0.961 - Mlig455_016753 {REF} {Length: 9320} {Pfam: Ion transport protein [PF00520.33, score=813.2]; Voltage gated calcium channel IQ domain [PF08763.13, score=96.3]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=90.6]; Polycystin cation channel [PF08016.14, score=22.4]} {Human: ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [RH, Score=1812, Expect=0.0]; ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [RH, Score=1812, Expect=0.0]; ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [RH, Score=1773, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [RH, Score=1738, Expect=0.0]} {Mouse: ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [RH, Score=1822, Expect=0.0]; ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [RH, Score=1766, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [RH, Score=1935, Expect=0.0]} {Celegans: WBGene00001187, egl-19, Voltage-dependent L-type calcium channel subunit alpha, [RH, Score=1824, Expect=0.0]} {Smed: dd_Smed_v6_8899_0_20, dd_Smed_v6_8899_0_20, [RH, Score=1966, Expect=0.0]} {RNA1509_7565} {RNA1310_601} {RNA815_3074}
25. MligTC455_41318 183 3.81 Mlig455_061686

Neo: -

Age: -

1.817 - - - - 0.843 0.974 Mlig455_061686 {REF} {Length: 788} {TRANSSPLICED} {RNA1509_31046} {RNA1310_41579} {RNA815_19702}
26. MligTC455_50740 262 5.46 Mlig455_028088

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.630/0.00016

SFRP5 1.815 - - - - 0.860 0.955 Mlig455_028088 {REF} {Length: 2548} {Pfam: Fz domain [PF01392.24, score=93.7]} {Human: ENSG00000120057, SFRP5, secreted frizzled related protein 5, [RH, Score=158, Expect=5e-44]} {Mouse: ENSMUSG00000018822, Sfrp5, secreted frizzled-related sequence protein 5, [RH, Score=156, Expect=2e-43]} {Dmel: FBgn0027342, fz4, frizzled 4, [Score=100, Expect=4e-22]} {Celegans: WBGene00022242, sfrp-1, Secreted Frizzled-Related Protein, [RH, Score=163, Expect=2e-46]} {Smed: dd_Smed_v6_13985_0_1, dd_Smed_v6_13985_0_1, [RH, Score=164, Expect=2e-46]} {RNA1509_19129} {RNA1310_15120} {RNA815_30861}
27. MligTC455_43525 62 1.29 Mlig455_041078

Neo: -

Age: -

1.811 - - - - 0.858 0.953 Mlig455_041078 {REF} {Length: 3896} {RNA1509_39963} {RNA1310_38466} {RNA815_23614}
28. MligTC455_47996 109 2.27 Mlig455_066297

Neo: -

Age: -

1.808 - - 0.847 - - 0.961 Mlig455_066297 {REF} {Length: 1837} {RNA1509_42369} {RNA1310_15751} {RNA815_12389.1}
29. MligTC455_48348 938 19.55 Mlig455_027793, Mlig455_063494

Neo: -

Age: logFC(26M/2M)=-0.661

Region-enriched R8: 1.890/0.04247

SCN5A 1.804 - - 0.846 - 0.958 -

Mlig455_027793 {REF} {Length: 6955} {Pfam: Ion transport protein [PF00520.33, score=754.1]; Polycystin cation channel [PF08016.14, score=55.1]; ZIP Zinc transporter [PF02535.24, score=22.9]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=22.8]} {Human: ENSG00000183873, SCN5A, sodium voltage-gated channel alpha subunit 5, [RH, Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000032511, Scn5a, sodium channel, voltage-gated, type V, alpha, [Score=1260, Expect=0.0]; ENSMUSG00000001027, Scn4a, sodium channel, voltage-gated, type IV, alpha, [Score=1253, Expect=0.0]} {Dmel: FBgn0285944, para, paralytic, [Score=914, Expect=0.0]} {Celegans: WBGene00000367, cca-1, Voltage-dependent T-type calcium channel subunit alpha, [Score=452, Expect=2e-130]} {Smed: dd_Smed_v6_12243_0_1, dd_Smed_v6_12243_0_1, [RH, Score=1245, Expect=0.0]} {RNA1509_2331} {RNA1310_490.1} {RNA815_185.1}

Mlig455_063494 {REF} {Length: 7000} {Pfam: Ion transport protein [PF00520.33, score=755.0]; Polycystin cation channel [PF08016.14, score=55.6]; ZIP Zinc transporter [PF02535.24, score=23.8]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=22.8]} {Human: ENSG00000183873, SCN5A, sodium voltage-gated channel alpha subunit 5, [RH, Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000032511, Scn5a, sodium channel, voltage-gated, type V, alpha, [Score=1261, Expect=0.0]; ENSMUSG00000001027, Scn4a, sodium channel, voltage-gated, type IV, alpha, [Score=1240, Expect=0.0]} {Dmel: FBgn0285944, para, paralytic, [Score=914, Expect=0.0]} {Celegans: WBGene00001187, egl-19, Voltage-dependent L-type calcium channel subunit alpha, [Score=310, Expect=8e-85]} {Smed: dd_Smed_v6_12243_0_1, dd_Smed_v6_12243_0_1, [RH, Score=1244, Expect=0.0]} {RNA1509_2331} {RNA1310_490.1, RNA1509_2331} {RNA1509_2331, RNA815_185.1}
30. MligTC455_31292 287 5.97 Mlig455_059964

Neo: -

Age: logFC(26M/2M)=-0.518

1.802 - - - - 0.961 0.841 Mlig455_059964 {REF} {Length: 6272} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4549) [PF15082.8, score=142.8]; Ligand-gated ion channel [PF00060.28, score=50.1]} {Mouse: ENSMUSG00000075225, Ccdc162, coiled-coil domain containing 162, [Score=914, Expect=0.0]} {Dmel: FBgn0052704, Ir8a, Ionotropic receptor 8a, [Score=55.5, Expect=5e-07]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [Score=58.2, Expect=6e-08]} {Smed: dd_Smed_v6_16643_0_1, dd_Smed_v6_16643_0_1, [RH, Score=706, Expect=0.0]} {RNA1509_21772} {RNA1310_311.1} {RNA815_144.1}
31. MligTC455_29373 3437 71.6 Mlig455_034659

Neo: -

Age: -

1.8 - - 0.839 - 0.961 - Mlig455_034659 {REF} {Length: 1882} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}
32. MligTC455_50432 2499 52.06 Mlig455_053597

Neo: -

Age: -

Region-enriched R8: 1.161/0.01787

ANKRD24 1.798 - - 0.844 - 0.954 - Mlig455_053597 {REF} {Length: 2565} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=56.7]; Ankyrin repeats (3 copies) [PF12796.9, score=56.0]; Ankyrin repeats (many copies) [PF13857.8, score=51.0]; Ankyrin repeat [PF00023.32, score=32.1]; Ankyrin repeat [PF13606.8, score=25.0]} {Human: ENSG00000089847, ANKRD24, ankyrin repeat domain 24, [Score=59.3, Expect=1e-08]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=59.3, Expect=5e-09]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=58.9, Expect=6e-09]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=58.9, Expect=7e-09]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=58.2, Expect=1e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=58.2, Expect=1e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=54.7, Expect=3e-07]} {Celegans: WBGene00006490, kdin-1, KiDINs220 (Vertebrate scaffold protein) homolog, [Score=50.8, Expect=2e-06]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=55.8, Expect=5e-08]} {RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000} {RNA1310_25280, RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000} {RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000, RNA815_12634}
33. MligTC455_37161 216 4.49 Mlig455_015360

Neo: -

Age: -

TTC28 1.797 - - 0.805 - - 0.992 Mlig455_015360 {REF} {Length: 6317} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF13424.8, score=62.3]; Tetratricopeptide repeat [PF07719.19, score=48.6]; Tetratricopeptide repeat [PF13181.8, score=43.1]; Tetratricopeptide repeat [PF00515.30, score=38.7]; CHAT domain [PF12770.9, score=38.0]; Tetratricopeptide repeat [PF14559.8, score=21.8]; Tetratricopeptide repeat [PF13431.8, score=20.4]; Tetratricopeptide repeat [PF13176.8, score=19.4]} {Human: ENSG00000100154, TTC28, tetratricopeptide repeat domain 28, [Score=66.6, Expect=5e-10]} {Mouse: ENSMUSG00000033209, Ttc28, tetratricopeptide repeat domain 28, [Score=67.8, Expect=1e-10]} {RNA1509_5411} {RNA1310_761.2} {RNA815_600}
34. MligTC455_47476 7650 159.38 Mlig455_011139

Neo: -

Age: logFC(26M/2M)=-0.342

RSPH1 1.793 - - - 0.814 0.979 - Mlig455_011139 {REF} {Length: 1427} {Pfam: MORN repeat [PF02493.22, score=123.5]} {Human: ENSG00000160188, RSPH1, radial spoke head component 1, [RH, Score=256, Expect=6e-84]} {Mouse: ENSMUSG00000024033, Rsph1, radial spoke head 1 homolog (Chlamydomonas), [RH, Score=266, Expect=8e-88]} {Dmel: FBgn0032478, CG5458, [RH, Score=149, Expect=6e-42]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=59.3, Expect=1e-09]} {Smed: dd_Smed_v6_3321_0_1, dd_Smed_v6_3321_0_1, [RH, Score=306, Expect=6e-104]} {RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1310_22398, RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1509_10402, RNA1509_5779, RNA1509_6982, RNA815_10865}
35. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

VASH2 1.792 - - - 0.836 0.956 - Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
36. MligTC455_13715 49 1.03 Mlig455_000810

Neo: -

Age: Down-Up-Down

CETN2 1.786 - - - - 0.825 0.961 Mlig455_000810 {REF} {Length: 852} {Pfam: EF-hand domain pair [PF13499.8, score=36.4]; EF hand [PF00036.34, score=34.7]; EF-hand domain [PF13405.8, score=33.7]; EF-hand domain pair [PF13833.8, score=26.0]; EF hand [PF13202.8, score=19.9]} {Human: ENSG00000147400, CETN2, centrin 2, [Score=57.0, Expect=5e-10]; ENSG00000143933, CALM2, calmodulin 2, [Score=56.6, Expect=8e-10]; ENSG00000160014, CALM3, calmodulin 3, [Score=56.6, Expect=2e-10]; ENSG00000198668, CALM1, calmodulin 1, [Score=56.6, Expect=2e-10]; ENSG00000177143, CETN1, centrin 1, [Score=55.1, Expect=2e-09]} {Mouse: ENSMUSG00000050996, Cetn1, centrin 1, [Score=63.2, Expect=2e-12]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=58.2, Expect=5e-11]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=58.5, Expect=1e-11]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=58.2, Expect=3e-11]} {RNA1310_39411} {RNA815_27208}
37. MligTC455_40846 835 17.39 Mlig455_030827, Mlig455_047790

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

KCNMA1 1.784 - - - - 0.957 0.827

Mlig455_030827 {REF} {Length: 3985} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=88.0]; Ion channel [PF07885.18, score=46.9]; Ion transport protein [PF00520.33, score=25.2]; TrkA-N domain [PF02254.20, score=24.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=482, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=481, Expect=3e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=339, Expect=4e-99]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=459, Expect=8e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=479, Expect=1e-151]} {RNA1509_12064, RNA1509_38332} {RNA1310_2763, RNA1509_38332} {RNA1509_38332, RNA815_792.1}

Mlig455_047790 {REF} {Length: 4417} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=87.7]; Ion channel [PF07885.18, score=46.7]; TrkA-N domain [PF02254.20, score=23.6]; Ion transport protein [PF00520.33, score=21.9]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=479, Expect=1e-148]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=478, Expect=7e-149]} {Dmel: FBgn0003429, slo, slowpoke, [Score=340, Expect=2e-98]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=455, Expect=1e-140]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=475, Expect=3e-148]} {RNA1509_38332, RNA1509_48456} {RNA1310_2763, RNA1509_48456} {RNA1509_48456, RNA815_792.1}
38. MligTC455_50334 4713 98.19 Mlig455_047582

Neo: -

Age: Down-Up-Up

Region-enriched R2: 4.063/0.00049

1.781 - - - - 0.827 0.954 Mlig455_047582 {REF} {Length: 1011} {Pfam: Globin [PF00042.24, score=71.0]} {Smed: dd_Smed_v6_2237_0_1, dd_Smed_v6_2237_0_1, [RH, Score=59.7, Expect=6e-12]} {RNA1509_8100} {RNA1310_38363} {RNA815_18105}
39. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

1.779 - - - 0.798 0.981 - Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
40. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

LEXM 1.778 - - - 0.821 0.957 - Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
41. MligTC455_44850 2381 49.6 Mlig455_014259

Neo: -

Age: logFC(26M/2M)=-0.355

LEXM 1.773 - - - 0.794 0.979 - Mlig455_014259 {REF} {Length: 2739} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1, RNA1509_2011} {RNA1509_2011, RNA815_5377}
42. MligTC455_45950 240 5.01 Mlig455_015572

Neo: -

Age: Down-Up-Down

MNS1 1.771 - - - - 0.806 0.965 Mlig455_015572 {REF} {Length: 2211} {TRANSSPLICED} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=239.7]} {Human: ENSG00000138587, MNS1, meiosis specific nuclear structural 1, [RH, Score=312, Expect=9e-101]} {Mouse: ENSMUSG00000032221, Mns1, meiosis-specific nuclear structural protein 1, [RH, Score=338, Expect=5e-111]} {Smed: dd_Smed_v6_4463_0_1, dd_Smed_v6_4463_0_1, [RH, Score=380, Expect=2e-127]} {RNA1509_5133} {RNA1310_11484} {RNA815_4005}
43. MligTC455_30435 177 3.69 Mlig455_005918, Mlig455_019586, Mlig455_031986, Mlig455_068070

Neo: -

Age: -

1.767 - - - 0.809 - 0.958

Mlig455_005918 {REF} {Length: 324} {NoTransDecoderORF} {RNA1509_11239} {RNA1310_7897.2} {RNA815_2064.1}

Mlig455_019586 {REF} {Length: 554} {NoTransDecoderORF} {RNA1509_11239} {RNA1310_50394} {RNA815_2064.1}

Mlig455_031986 {REF} {Length: 317} {NoTransDecoderORF} {RNA1509_11239} {RNA1310_50394} {RNA815_2064.1}

Mlig455_068070 {REF} {Length: 654} {NoTransDecoderORF} {RNA1509_11239} {RNA1310_50394} {RNA815_2064.1}
44. MligTC455_41986 57 1.19 Mlig455_027306

Neo: -

Age: -

TCF23 1.767 - - - - 0.808 0.959 Mlig455_027306 {REF} {Length: 1046} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=41.9]} {Human: ENSG00000163792, TCF23, transcription factor 23, [RH, Score=86.3, Expect=5e-22]} {Mouse: ENSMUSG00000006642, Tcf23, transcription factor 23, [RH, Score=84.3, Expect=2e-21]} {Dmel: FBgn0011277, HLH4C, Helix loop helix protein 4C, [Score=48.1, Expect=4e-08]} {Celegans: WBGene00001959, hlh-15, Helix Loop Helix, [Score=45.8, Expect=7e-08]} {Smed: dd_Smed_v6_16070_0_1, dd_Smed_v6_16070_0_1, [Score=52.4, Expect=9e-10]} {RNA1310_4676} {RNA815_18327.1}
45. MligTC455_13468 36 0.75 Mlig455_044410, Mlig455_044445

Neo: -

Age: -

1.762 - - - - 0.806 0.956

Mlig455_044410 {REF} {Length: 1049} {Pfam: Dynein light chain type 1 [PF01221.20, score=56.6]; EF-hand domain pair [PF13499.8, score=29.7]; EF hand [PF00036.34, score=25.9]; EF-hand domain [PF13405.8, score=20.6]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [Score=130, Expect=9e-39]} {RNA1310_56608} {RNA815_53279}

Mlig455_044445 {REF} {Length: 1016} {Pfam: Dynein light chain type 1 [PF01221.20, score=56.6]; EF-hand domain pair [PF13499.8, score=29.7]; EF hand [PF00036.34, score=25.9]; EF-hand domain [PF13405.8, score=20.6]} {Smed: dd_Smed_v6_1881_0_1, dd_Smed_v6_1881_0_1, [Score=130, Expect=9e-39]} {RNA1310_56608} {RNA815_53279}
46. MligTC455_15367 110 2.3 Mlig455_067477, Mlig455_067486

Neo: -

Age: -

TCF23 1.762 - - - - 0.798 0.964

Mlig455_067477 {REF} {Length: 756} {Pfam: Helix-loop-helix DNA-binding domain [PF00010.28, score=41.4]} {Human: ENSG00000163792, TCF23, transcription factor 23, [RH, Score=88.2, Expect=2e-22]} {Mouse: ENSMUSG00000006642, Tcf23, transcription factor 23, [RH, Score=85.9, Expect=1e-21]} {Dmel: FBgn0011277, HLH4C, Helix loop helix protein 4C, [Score=49.3, Expect=3e-08]} {Celegans: WBGene00001959, hlh-15, Helix Loop Helix, [Score=47.0, Expect=5e-08]} {Smed: dd_Smed_v6_16070_0_1, dd_Smed_v6_16070_0_1, [Score=52.8, Expect=1e-09]} {RNA1310_4676} {RNA815_18327.1}

Mlig455_067486 {REF} {Length: 273} {NoTransDecoderORF} {RNA1310_4676} {RNA815_18327.2}
47. MligTC455_22507 46 0.95 Mlig455_029421

Neo: -

Age: -

1.762 - - 0.796 - 0.966 - Mlig455_029421 {REF} {Length: 1886} {RNA1310_25903.1} {RNA815_25103}
48. MligTC455_33841 898 18.71 Mlig455_004818, Mlig455_004886

Neo: -

Age: logFC(26M/2M)=-0.301

Region-enriched R2: 1.729/0.00165

CDKL1 1.759 0.952 - - - 0.807 -

Mlig455_004818 {REF} {Length: 2858} {Pfam: Protein kinase domain [PF00069.27, score=245.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.2]; RIO1 family [PF01163.24, score=22.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=427, Expect=2e-147]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=4e-145]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=430, Expect=6e-149]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=421, Expect=1e-145]} {Dmel: FBgn0031730, CG7236, [RH, Score=379, Expect=7e-128]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=395, Expect=1e-133]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=478, Expect=1e-167]} {RNA1509_19679} {RNA1310_6686.2} {RNA815_5397}

Mlig455_004886 {REF} {Length: 2943} {Pfam: Protein kinase domain [PF00069.27, score=245.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=115.0]; RIO1 family [PF01163.24, score=22.4]; Haspin like kinase domain [PF12330.10, score=17.8]; ABC1 atypical kinase-like domain [PF03109.18, score=17.7]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=428, Expect=6e-148]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=422, Expect=4e-146]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=431, Expect=2e-149]; ENSMUSG00000033966, Cdkl4, cyclin-dependent kinase-like 4, [RH, Score=422, Expect=6e-146]} {Dmel: FBgn0031730, CG7236, [RH, Score=380, Expect=3e-128]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [RH, Score=392, Expect=2e-132]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=479, Expect=5e-168]} {RNA1509_19679} {RNA1310_6686.2} {RNA815_5397}
49. MligTC455_08638 310 6.46 Mlig455_062686

Neo: -

Age: Up-Down-Down

CTNND2 1.757 - - - - 0.950 0.807 Mlig455_062686 {REF} {Length: 6196} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=111.2]; HEAT repeats [PF13646.8, score=23.1]} {Human: ENSG00000169862, CTNND2, catenin delta 2, [RH, Score=358, Expect=1e-105]; ENSG00000144283, PKP4, plakophilin 4, [RH, Score=341, Expect=3e-99]} {Mouse: ENSMUSG00000022240, Ctnnd2, catenin (cadherin associated protein), delta 2, [RH, Score=353, Expect=1e-103]; ENSMUSG00000026991, Pkp4, plakophilin 4, [RH, Score=341, Expect=1e-99]} {Dmel: FBgn0260799, p120ctn, Adherens junction protein p120, [RH, Score=397, Expect=7e-124]} {Celegans: WBGene00002175, jac-1, Juxtamembrane domain-associated catenin, [RH, Score=303, Expect=4e-86]} {Smed: dd_Smed_v6_6256_0_1, dd_Smed_v6_6256_0_1, [RH, Score=241, Expect=5e-67]} {RNA1509_13591} {RNA1310_6045} {RNA815_14763}
50. MligTC455_25411 17 0.35 Mlig455_026200

Neo: -

Age: -

1.756 - - 0.795 - - 0.961 Mlig455_026200 {REF} {Length: 2470} {Pfam: Variant SH3 domain [PF07653.19, score=21.7]; Variant SH3 domain [PF14604.8, score=20.9]} {Smed: dd_Smed_v6_14584_0_1, dd_Smed_v6_14584_0_1, [Score=103, Expect=5e-23]} {RNA1509_45271} {RNA1310_5741} {RNA815_46868}
51. MligTC455_43766 2863 59.66 Mlig455_001907

Neo: -

Age: logFC(26M/2M)=-0.394

EFHB 1.756 - - - 0.787 0.969 - Mlig455_001907 {REF} {Length: 2219} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=45.4]; EF hand [PF00036.34, score=42.6]; EF-hand domain [PF13405.8, score=40.6]; Family of unknown function (DUF5580) [PF17743.3, score=32.4]; EF hand [PF13202.8, score=31.5]; EF-hand domain pair [PF13833.8, score=19.0]} {Human: ENSG00000163576, EFHB, EF-hand domain family member B, [Score=361, Expect=9e-117]} {Mouse: ENSMUSG00000023931, Efhb, EF hand domain family, member B, [Score=332, Expect=2e-104]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=53.5, Expect=6e-08]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=52.4, Expect=8e-08]} {Smed: dd_Smed_v6_11909_0_1, dd_Smed_v6_11909_0_1, [Score=325, Expect=5e-105]} {RNA1509_2205} {RNA1310_7693, RNA1509_2205} {RNA1509_2205, RNA815_3913}
52. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

GRIA2 1.754 - - - - 0.972 0.782

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
53. MligTC455_17960 44 0.92 Mlig455_021047

Neo: -

Age: -

Region-enriched R2: 4.515/0.04131
Region-enriched R4: 3.266/0.03072

1.75 - - - - 0.789 0.961 Mlig455_021047 {REF} {Length: 2114} {Pfam: SH3 domain [PF17902.3, score=25.9]; Plectin repeat [PF00681.22, score=23.8]} {Smed: dd_Smed_v6_16329_0_1, dd_Smed_v6_16329_0_1, [Score=56.6, Expect=2e-08]} {RNA1509_53557} {RNA1310_11354} {RNA815_18566}
54. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

CCDC39 1.747 - - - 0.793 0.954 - Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
55. MligTC455_49669 24 0.51 Mlig455_047621

Neo: -

Age: -

WSCD2 1.741 - - - - 0.779 0.962 Mlig455_047621 {REF} {Length: 870} {Pfam: WSC domain [PF01822.21, score=57.1]} {Human: ENSG00000075035, WSCD2, WSC domain containing 2, [Score=54.3, Expect=3e-08]} {Mouse: ENSMUSG00000063430, Wscd2, WSC domain containing 2, [Score=54.3, Expect=2e-08]} {RNA1509_29094} {RNA1310_81328} {RNA815_51632}
56. MligTC455_54077 937 19.53 Mlig455_032159, Mlig455_032165

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.640

TLL2 1.741 - - 0.766 - 0.975 -

Mlig455_032159 {REF} {Length: 1358} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}

Mlig455_032165 {REF} {Length: 1696} {Pfam: CUB domain [PF00431.22, score=63.7]} {Human: ENSG00000095587, TLL2, tolloid like 2, [Score=62.8, Expect=4e-10]; ENSG00000107611, CUBN, cubilin, [Score=62.0, Expect=1e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=61.2, Expect=1e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=68.9, Expect=4e-12]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}
57. MligTC455_49180 501 10.44 Mlig455_030419

Neo: -

Age: logFC(26M/2M)=-0.221

GRIK1 1.739 - - 0.783 - 0.956 - Mlig455_030419 {REF} {Length: 3001} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=21.2]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=78.2, Expect=4e-14]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=75.5, Expect=3e-13]} {Mouse: ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=76.3, Expect=1e-13]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=75.5, Expect=2e-13]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=68.2, Expect=2e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=73.2, Expect=4e-13]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
58. MligTC455_52118 5757 119.94 Mlig455_069122

Neo: -

Age: logFC(26M/2M)=0.892

CFAP58 1.737 - - - 0.763 0.974 - Mlig455_069122 {REF} {Length: 3136} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=23.0]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=923, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=991, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=1e-40]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1103, Expect=0.0]} {RNA1509_282} {RNA1310_4570, RNA1509_282} {RNA1509_282, RNA815_1528}
59. MligTC455_24352 968 20.17 Mlig455_024177, Mlig455_024195

Neo: -

Age: logFC(26M/2M)=-0.541

RHBG 1.736 - - - - 0.774 0.962

Mlig455_024177 {REF} {Length: 2334} {Pfam: Ammonium Transporter Family [PF00909.23, score=240.1]} {Human: ENSG00000132677, RHBG, Rh family B glycoprotein (gene/pseudogene), [RH, Score=384, Expect=5e-129]} {Mouse: ENSMUSG00000023926, Rhag, Rhesus blood group-associated A glycoprotein, [RH, Score=370, Expect=7e-124]; ENSMUSG00000104445, Rhbg, Rhesus blood group-associated B glycoprotein, [RH, Score=353, Expect=5e-117]} {Dmel: FBgn0028699, Rh50, [RH, Score=372, Expect=3e-124]} {Celegans: WBGene00004358, rhr-1, RH (Rhesus) antigen Related, [RH, Score=357, Expect=1e-118]} {Smed: dd_Smed_v6_1882_0_2, dd_Smed_v6_1882_0_2, [Score=400, Expect=1e-135]} {RNA1509_21244, RNA1509_31957, RNA1509_49768} {RNA1310_10990, RNA1509_21244, RNA1509_31957, RNA1509_49768} {RNA1509_21244, RNA1509_31957, RNA1509_49768, RNA815_4501.1}

Mlig455_024195 {REF} {Length: 3261} {Pfam: Ammonium Transporter Family [PF00909.23, score=236.6]} {Human: ENSG00000132677, RHBG, Rh family B glycoprotein (gene/pseudogene), [RH, Score=382, Expect=3e-128]} {Mouse: ENSMUSG00000104445, Rhbg, Rhesus blood group-associated B glycoprotein, [RH, Score=352, Expect=5e-117]} {Dmel: FBgn0028699, Rh50, [RH, Score=372, Expect=6e-125]} {Celegans: WBGene00004358, rhr-1, RH (Rhesus) antigen Related, [Score=354, Expect=8e-118]} {Smed: dd_Smed_v6_1882_0_2, dd_Smed_v6_1882_0_2, [Score=397, Expect=9e-135]} {RNA1509_21244} {RNA1310_10990} {RNA815_4501.1}
60. MligTC455_37139 1583 32.98 Mlig455_017144, Mlig455_019681

Neo: -

Age: -

TRPM3 1.736 - - - 0.772 0.964 -

Mlig455_017144 {REF} {Length: 5140} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=159.9]; SLOG in TRPM, prokaryote [PF18171.3, score=53.1]; Ion transport protein [PF00520.33, score=37.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=358, Expect=3e-102]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=360, Expect=4e-103]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=335, Expect=1e-95]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=243, Expect=5e-65]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [RH, Score=502, Expect=2e-155]} {RNA1509_6375} {RNA1310_1012, RNA1509_6375} {RNA1509_6375, RNA815_5496.1}

Mlig455_019681 {REF} {Length: 5114} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=161.2]; SLOG in TRPM, prokaryote [PF18171.3, score=53.2]; Ion transport protein [PF00520.33, score=37.2]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=364, Expect=5e-103]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=363, Expect=1e-102]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=345, Expect=9e-97]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=239, Expect=1e-63]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [RH, Score=508, Expect=1e-157]} {RNA1509_43040, RNA1509_6375} {RNA1310_1012, RNA1509_43040} {RNA1509_43040, RNA815_5496.1}
61. MligTC455_26600 111 2.32 Mlig455_000691

Neo: -

Age: logFC(26M/2M)=-0.305

Region-enriched R2: 4.160/0.03510

1.732 - - - - 0.773 0.959 Mlig455_000691 {REF} {Length: 6281} {Smed: dd_Smed_v6_17076_0_1, dd_Smed_v6_17076_0_1, [RH, Score=214, Expect=1e-56]} {RNA1509_20580} {RNA1310_21461} {RNA815_12493}
62. MligTC455_16203 30 0.63 Mlig455_025342, Mlig455_025391

Neo: -

Age: -

VAX1 1.731 - - - - 0.776 0.955

Mlig455_025342 {REF} {Length: 1864} {Pfam: Homeodomain [PF00046.31, score=79.6]; Homeobox KN domain [PF05920.13, score=19.0]} {Human: ENSG00000148704, VAX1, ventral anterior homeobox 1, [RH, Score=134, Expect=2e-38]} {Mouse: ENSMUSG00000006270, Vax1, ventral anterior homeobox 1, [RH, Score=134, Expect=1e-38]} {Dmel: FBgn0008646, E5, [Score=89.7, Expect=2e-21]} {Celegans: WBGene00000430, ceh-5, Homeobox protein ceh-5, [RH, Score=94.4, Expect=2e-25]} {Smed: dd_Smed_v6_56082_0_1, dd_Smed_v6_56082_0_1, [Score=79.0, Expect=5e-19]} {RNA1310_103668} {RNA815_54191}

Mlig455_025391 {REF} {Length: 2433} {Pfam: Homeodomain [PF00046.31, score=77.1]} {Human: ENSG00000148704, VAX1, ventral anterior homeobox 1, [RH, Score=135, Expect=2e-35]} {Mouse: ENSMUSG00000006270, Vax1, ventral anterior homeobox 1, [RH, Score=135, Expect=2e-35]} {Dmel: FBgn0008646, E5, [Score=90.1, Expect=6e-19]} {Celegans: WBGene00000430, ceh-5, Homeobox protein ceh-5, [Score=88.6, Expect=8e-21]} {Smed: dd_Smed_v6_56082_0_1, dd_Smed_v6_56082_0_1, [Score=79.0, Expect=5e-17]} {RNA1509_50200} {RNA1310_103668} {RNA815_54191}
63. MligTC455_35597 38 0.8 Mlig455_027912

Neo: -

Age: Down-Up-Down

1.729 - - - - 0.772 0.957 Mlig455_027912 {REF} {Length: 4150} {TRANSSPLICED} {RNA1509_54389} {RNA1310_1516.1} {RNA815_1066.1}
64. MligTC455_25356 111 2.32 Mlig455_045897

Neo: -

Age: -

MUS81 1.728 - 0.767 - - - 0.961 Mlig455_045897 {REF} {Length: 4633} {TRANSSPLICED} {Pfam: ERCC4 domain [PF02732.17, score=80.3]} {Human: ENSG00000172732, MUS81, MUS81 structure-specific endonuclease subunit, [RH, Score=180, Expect=2e-49]} {Mouse: ENSMUSG00000024906, Mus81, MUS81 structure-specific endonuclease subunit, [RH, Score=183, Expect=6e-50]} {Dmel: FBgn0040347, mus81, [RH, Score=132, Expect=3e-33]} {Celegans: WBGene00016602, mus-81, [RH, Score=80.1, Expect=1e-15]} {Smed: dd_Smed_v6_11322_0_4, dd_Smed_v6_11322_0_4, [RH, Score=173, Expect=2e-46]} {RNA1509_12267} {RNA1310_3794} {RNA815_3575.1}
65. MligTC455_21523 317 6.61 Mlig455_029394

Neo: -

Age: -

Region-enriched R6: 2.246/0.01608

Regeneration-downregulated R6: -3.517

Regeneration-depleted R6: -3.517

MYL4 1.727 - - - - 0.772 0.955 Mlig455_029394 {REF} {Length: 861} {Pfam: EF-hand domain pair [PF13499.8, score=40.0]; EF hand [PF00036.34, score=25.2]; EF-hand domain pair [PF13833.8, score=24.8]; EF-hand domain [PF13405.8, score=22.4]} {Human: ENSG00000198336, MYL4, myosin light chain 4, [Score=57.4, Expect=7e-10]; ENSG00000160808, MYL3, myosin light chain 3, [Score=55.5, Expect=4e-09]} {Mouse: ENSMUSG00000059741, Myl3, myosin, light polypeptide 3, [Score=57.4, Expect=5e-10]; ENSMUSG00000061086, Myl4, myosin, light polypeptide 4, [Score=56.6, Expect=7e-10]} {Dmel: FBgn0004687, Mlc-c, Myosin light chain cytoplasmic, [Score=70.1, Expect=3e-15]} {Celegans: WBGene00011734, mlc-5, Myosin-2 essential light chain, [Score=61.6, Expect=3e-12]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=48.5, Expect=6e-07]} {RNA1509_43205} {RNA1310_45370, RNA1509_43205} {RNA1509_43205, RNA815_24120.1}
66. MligTC455_33364 348 7.24 Mlig455_009410, Mlig455_016109, Mlig455_026502, Mlig455_027903, Mlig455_036913, Mlig455_066713, Mlig455_068644, Mlig455_070501

Neo: -

Age: logFC(26M/2M)=-0.641

NYNRIN 1.725 0.743 - - - 0.982 -

Mlig455_009410 {REF} {Length: 6826} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=304.8]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=92.4, Expect=4e-20]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=209, Expect=1e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=301, Expect=1e-97]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_016109 {REF} {Length: 3482} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.5]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.8]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=55.7]; Aspartyl protease [PF13650.8, score=21.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=7e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=124, Expect=4e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=425, Expect=7e-131]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}

Mlig455_026502 {REF} {Length: 698} {Pfam: Zinc knuckle [PF00098.25, score=27.8]} {RNA1509_38652} {RNA1310_25149.1} {RNA815_13280}

Mlig455_027903 {REF} {Length: 3748} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.7]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=51.2]; Aspartyl protease [PF13650.8, score=21.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=121, Expect=5e-27]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=122, Expect=1e-27]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=432, Expect=8e-134]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_036913 {REF} {Length: 639} {RNA1509_48973} {RNA1310_39833} {RNA815_36286}

Mlig455_066713 {REF} {Length: 2873} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=122.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.1]; Integrase zinc binding domain [PF17921.3, score=77.1]; Integrase core domain [PF00665.28, score=53.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=117, Expect=3e-26]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=117, Expect=4e-26]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=237, Expect=1e-65]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_068644 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.2]; Integrase zinc binding domain [PF17921.3, score=79.7]; Integrase core domain [PF00665.28, score=49.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=130, Expect=4e-30]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=6e-29]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=313, Expect=5e-93]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_070501 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=123.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.2]; Integrase zinc binding domain [PF17921.3, score=76.5]; Integrase core domain [PF00665.28, score=54.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=2e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=1e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=322, Expect=2e-96]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}
67. MligTC455_48560 57 1.18 Mlig455_046453

Neo: -

Age: -

Region-enriched R2: 5.673/0.03292

1.723 - - - - 0.772 0.951 Mlig455_046453 {REF} {Length: 1321} {TRANSSPLICED} {RNA1310_43065} {RNA815_11099}
68. MligTC455_50891 492 10.25 Mlig455_062495

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.898

Region-enriched R4: 1.209/0.04127

1.718 - - - 0.739 - 0.979 Mlig455_062495 {REF} {Length: 25747} {TRANSSPLICED} {Mouse: ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [Score=62.4, Expect=2e-08]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [Score=62.4, Expect=2e-08]} {Dmel: FBgn0052656, Muc11A, Mucin 11A, [Score=162, Expect=5e-39]} {RNA1509_3715} {RNA1310_899} {RNA815_287}
69. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

MX2 1.717 - - 0.767 - 0.950 - Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
70. MligTC455_37361 5370 111.88 Mlig455_043035

Neo: -

Age: logFC(26M/2M)=-0.378

CFAP52 1.715 - - 0.754 - 0.961 - Mlig455_043035 {REF} {Length: 2490} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.1]; WD40-like domain [PF17005.7, score=27.1]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=441, Expect=1e-145]} {Celegans: WBGene00004895, smu-1, SMU-1; Suppressor of Mec and Unc defects, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=841, Expect=0.0]} {RNA1509_1341} {RNA1310_8859, RNA1509_1341} {RNA1509_1341, RNA815_2855}
71. MligTC455_49348 106 2.22 Mlig455_042275

Neo: -

Age: -

1.713 - - 0.759 - - 0.954 Mlig455_042275 {REF} {Length: 1278} {NoTransDecoderORF} {RNA1509_58228} {RNA1310_48769.2} {RNA815_29333}
72. MligTC455_32519 147 3.06 Mlig455_017549

Neo: -

Age: logFC(26M/2M)=-0.495

NWD2 1.71 - 0.759 - - 0.951 - Mlig455_017549 {REF} {Length: 6334} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA ATPase domain [PF13191.8, score=38.4]; NACHT domain [PF05729.14, score=34.5]; AAA domain [PF13481.8, score=20.7]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=347, Expect=8e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=340, Expect=1e-96]} {Dmel: FBgn0038397, CG10185, [Score=472, Expect=9e-143]} {Celegans: WBGene00020254, T05C3.2, [Score=527, Expect=1e-162]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=380, Expect=2e-110]} {RNA1509_23488} {RNA1310_497.1} {RNA815_237}
73. MligTC455_25107 160 3.33 Mlig455_002517, Mlig455_002651

Neo: -

Age: -

GABRB2 1.709 - - - 0.748 - 0.961

Mlig455_002517 {REF} {Length: 3630} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=169.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=153.0]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [RH, Score=414, Expect=6e-139]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [RH, Score=408, Expect=5e-137]} {Dmel: FBgn0010240, Lcch3, Ligand-gated chloride channel homolog 3, [RH, Score=462, Expect=2e-158]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=458, Expect=2e-156]} {Smed: dd_Smed_v6_25116_0_1, dd_Smed_v6_25116_0_1, [RH, Score=484, Expect=5e-167]} {RNA1509_47435} {RNA1310_12876.1, RNA1509_47435} {RNA1509_47435, RNA815_12505}

Mlig455_002651 {REF} {Length: 3208} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=169.7]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=153.8]} {Human: ENSG00000145864, GABRB2, gamma-aminobutyric acid type A receptor beta2 subunit, [RH, Score=413, Expect=6e-139]} {Mouse: ENSMUSG00000007653, Gabrb2, gamma-aminobutyric acid (GABA) A receptor, subunit beta 2, [RH, Score=408, Expect=5e-137]} {Dmel: FBgn0010240, Lcch3, Ligand-gated chloride channel homolog 3, [RH, Score=462, Expect=1e-158]} {Celegans: WBGene00001512, gab-1, Gamma-aminobutyric acid receptor subunit beta, [Score=459, Expect=7e-157]} {Smed: dd_Smed_v6_25116_0_1, dd_Smed_v6_25116_0_1, [RH, Score=484, Expect=5e-167]} {RNA1509_47435} {RNA1310_12876.1} {RNA815_12505}
74. MligTC455_48704 743 15.47 Mlig455_022999

Neo: -

Age: -

CALU 1.709 - - 0.757 - - 0.952 Mlig455_022999 {REF} {Length: 1703} {Pfam: EF hand [PF00036.34, score=76.1]; EF-hand domain pair [PF13499.8, score=68.2]; EF hand [PF13202.8, score=66.2]; EF-hand domain [PF13405.8, score=58.2]; EF-hand domain pair [PF13833.8, score=42.4]; Dockerin type I domain [PF00404.20, score=22.5]} {Human: ENSG00000128595, CALU, calumenin, [Score=81.3, Expect=1e-16]} {Mouse: ENSMUSG00000029767, Calu, calumenin, [Score=82.4, Expect=4e-17]} {Dmel: FBgn0025682, scf, supercoiling factor, [Score=86.3, Expect=2e-19]} {Celegans: WBGene00017240, calu-2, CALUmenin (Calcium-binding protein) homolog, [Score=60.8, Expect=3e-10]} {Smed: dd_Smed_v6_1417_0_1, dd_Smed_v6_1417_0_1, [Score=84.0, Expect=4e-18]} {RNA1509_23307, RNA1509_4643, RNA1509_9442} {RNA1310_23219, RNA1509_23307, RNA1509_9442} {RNA1509_23307, RNA1509_9442, RNA815_9251.1}
75. MligTC455_48636 341 7.11 Mlig455_011518, Mlig455_011596

Neo: -

Age: logFC(26M/2M)=-0.426

Region-enriched R8: 3.002/0.00945

ANK2 1.704 - - - 0.754 - 0.950

Mlig455_011518 {REF} {Length: 3815} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=62.1]; Ankyrin repeats (many copies) [PF13637.8, score=60.6]; Ankyrin repeats (many copies) [PF13857.8, score=58.3]; Ankyrin repeat [PF00023.32, score=42.0]; Ankyrin repeat [PF13606.8, score=37.8]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=64.3, Expect=1e-09]; ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=63.5, Expect=2e-09]; ENSG00000131503, ANKHD1, ankyrin repeat and KH domain containing 1, [Score=61.2, Expect=9e-09]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=61.2, Expect=5e-10]} {Mouse: ENSMUSG00000040183, Ankrd6, ankyrin repeat domain 6, [Score=67.4, Expect=7e-11]; ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=64.7, Expect=7e-10]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=63.9, Expect=1e-09]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=57.4, Expect=6e-08]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=83.2, Expect=5e-16]} {RNA1509_43444} {RNA1310_500} {RNA815_20307}

Mlig455_011596 {REF} {Length: 3523} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=61.9]; Ankyrin repeats (many copies) [PF13637.8, score=60.4]; Ankyrin repeats (many copies) [PF13857.8, score=58.1]; Ankyrin repeat [PF00023.32, score=41.6]; Ankyrin repeat [PF13606.8, score=37.6]; Ion transport protein [PF00520.33, score=25.5]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=64.3, Expect=1e-09]; ENSG00000132466, ANKRD17, ankyrin repeat domain 17, [Score=63.9, Expect=2e-09]; ENSG00000135299, ANKRD6, ankyrin repeat domain 6, [Score=61.2, Expect=4e-10]} {Mouse: ENSMUSG00000040183, Ankrd6, ankyrin repeat domain 6, [Score=67.8, Expect=6e-11]; ENSMUSG00000055204, Ankrd17, ankyrin repeat domain 17, [Score=64.7, Expect=7e-10]} {Dmel: FBgn0043884, mask, multiple ankyrin repeats single KH domain, [Score=64.3, Expect=8e-10]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=61.6, Expect=3e-09]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=86.7, Expect=4e-17]} {RNA1509_43444} {RNA1310_500} {RNA815_20307}
76. MligTC455_37360 5178 107.87 Mlig455_043000

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.956

CFAP52 1.702 - - 0.738 - 0.964 - Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855}
77. MligTC455_51551 726 15.13 Mlig455_016695

Neo: -

Age: logFC(26M/2M)=-0.349

Region-enriched R4: 1.106/0.02364

1.702 - - - 0.752 - 0.950 Mlig455_016695 {REF} {Length: 1801} {RNA1509_36530} {RNA1310_20851.1, RNA1509_36530} {RNA1509_36530, RNA815_21142}
78. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

CFAP20 1.701 - - - 0.744 0.957 - Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
79. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

AC254952.1 1.7 - - - 0.739 0.961 - Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
80. MligTC455_34031 46 0.95 Mlig455_017240

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.785

Region-enriched R2: 4.623/0.00986

URGCP 1.698 - - - - 0.743 0.955 Mlig455_017240 {REF} {Length: 6540} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=22.8]; Dynamin family [PF00350.25, score=19.7]} {Human: ENSG00000106608, URGCP, upregulator of cell proliferation, [Score=150, Expect=3e-36]} {Mouse: ENSMUSG00000045868, Gvin1, GTPase, very large interferon inducible 1, [Score=468, Expect=1e-136]; ENSMUSG00000078606, Gm4070, predicted gene 4070, [Score=468, Expect=1e-136]} {RNA1509_38693} {RNA1310_2866, RNA1509_38693} {RNA1509_38693, RNA815_18695}
81. MligTC455_53211 1358 28.3 Mlig455_040065, Mlig455_040091

Neo: -

Age: logFC(26M/2M)=-0.362

Region-enriched R4: 1.888/0.01442

1.698 - - - 0.748 0.950 -

Mlig455_040065 {REF} {Length: 3189} {RNA1509_49542, RNA1509_9168} {RNA1310_8796.1, RNA1509_49542, RNA1509_9168} {RNA1509_49542, RNA1509_9168, RNA815_3100}

Mlig455_040091 {REF} {Length: 2759} {RNA1509_39791, RNA1509_9168} {RNA1310_8796.1, RNA1509_39791} {RNA1509_39791, RNA815_3100}
82. MligTC455_21640 262 5.46 Mlig455_052657

Neo: -

Age: -

SLC6A5 1.695 - - - 0.728 0.967 - Mlig455_052657 {REF} {Length: 4833} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=583.6]; BTB/POZ domain [PF00651.33, score=59.5]; BTB And C-terminal Kelch [PF07707.17, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=316, Expect=2e-92]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=315, Expect=5e-92]} {Dmel: FBgn0034911, CG5549, [Score=313, Expect=5e-89]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=228, Expect=2e-63]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=273, Expect=1e-78]} {RNA1509_27437} {RNA1310_7302.1} {RNA815_3821}
83. MligTC455_40915 873 18.19 Mlig455_042099

Neo: -

Age: -

SLC22A24 1.694 - - - - 0.741 0.953 Mlig455_042099 {REF} {Length: 4000} {Pfam: Sugar (and other) transporter [PF00083.26, score=102.5]; Major Facilitator Superfamily [PF07690.18, score=76.5]} {Human: ENSG00000197658, SLC22A24, solute carrier family 22 member 24, [Score=119, Expect=2e-27]; ENSG00000197901, SLC22A6, solute carrier family 22 member 6, [Score=115, Expect=1e-26]} {Mouse: ENSMUSG00000023828, Slc22a3, solute carrier family 22 (organic cation transporter), member 3, [Score=121, Expect=1e-28]} {Dmel: FBgn0039178, CG6356, [Score=127, Expect=1e-30]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=125, Expect=5e-30]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=85.9, Expect=2e-17]} {RNA1509_14287, RNA1509_8510} {RNA1310_10700.1, RNA1509_14287, RNA1509_8510} {RNA1509_14287, RNA1509_8510, RNA815_2513}
84. MligTC455_29454 50 1.05 Mlig455_065107

Neo: -

Age: -

CHRNA10 1.689 - - - - 0.729 0.960 Mlig455_065107 {REF} {Length: 3864} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=79.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=64.7, Expect=5e-11]; ENSG00000160716, CHRNB2, cholinergic receptor nicotinic beta 2 subunit, [Score=61.6, Expect=5e-10]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=71.6, Expect=2e-13]} {Celegans: WBGene00000051, acr-12, AcetylCholine Receptor; Nicotinic acetylcholine receptor-like subunit ACR-12, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_12146_0_1, dd_Smed_v6_12146_0_1, [Score=74.7, Expect=6e-15]} {RNA1509_57562} {RNA1310_27363} {RNA815_5685.1}
85. MligTC455_51602 235 4.9 Mlig455_046885

Neo: -

Age: -

Region-enriched R2: 3.077/0.00701

PCBP3 1.689 - - 0.715 - - 0.974 Mlig455_046885 {REF} {Length: 3838} {Pfam: KH domain [PF00013.31, score=177.6]; KH domain [PF07650.19, score=58.6]; KH domain [PF13083.8, score=27.1]; KH-like RNA-binding domain [PF16005.7, score=24.6]} {Human: ENSG00000183570, PCBP3, poly(rC) binding protein 3, [Score=305, Expect=3e-98]} {Mouse: ENSMUSG00000001120, Pcbp3, poly(rC) binding protein 3, [Score=298, Expect=1e-95]} {Dmel: FBgn0262737, mub, mushroom-body expressed, [RH, Score=282, Expect=3e-89]} {Celegans: WBGene00003978, pes-4, Patterned Expression Site, [RH, Score=228, Expect=1e-68]} {Smed: dd_Smed_v6_7334_0_1, dd_Smed_v6_7334_0_1, [Score=258, Expect=1e-78]} {RNA1509_47335} {RNA1310_5732, RNA1509_47335} {RNA1509_47335, RNA815_22034}
86. MligTC455_39873 22 0.46 Mlig455_049347

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.560

PKDCC 1.687 - - - - 0.723 0.964 Mlig455_049347 {REF} {Length: 2764} {Pfam: Protein-kinase domain of FAM69 [PF12260.10, score=30.6]; Protein kinase domain [PF00069.27, score=21.0]} {Human: ENSG00000162878, PKDCC, protein kinase domain containing, cytoplasmic, [RH, Score=192, Expect=4e-55]} {Mouse: ENSMUSG00000024247, Pkdcc, protein kinase domain containing, cytoplasmic, [RH, Score=180, Expect=9e-51]} {RNA1509_59008} {RNA1310_12305} {RNA815_21999}
87. MligTC455_23451 183 3.81 Mlig455_064157

Neo: -

Age: Up-Down-Down

SRP54 1.685 0.950 - - - - 0.735 Mlig455_064157 {REF} {Length: 2697} {TRANSSPLICED} {Pfam: SRP54-type protein, GTPase domain [PF00448.24, score=243.9]; Signal peptide binding domain [PF02978.21, score=89.0]; SRP54-type protein, helical bundle domain [PF02881.21, score=72.1]; AAA ATPase domain [PF13191.8, score=26.5]; AAA domain [PF13671.8, score=23.7]; Signal recognition particle receptor beta subunit [PF09439.12, score=23.0]; CobQ/CobB/MinD/ParA nucleotide binding domain [PF01656.25, score=22.8]; Zeta toxin [PF06414.14, score=22.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=19.7]; 6-phosphofructo-2-kinase [PF01591.20, score=18.9]; CobW/HypB/UreG, nucleotide-binding domain [PF02492.21, score=18.8]} {Human: ENSG00000100883, SRP54, signal recognition particle 54, [Score=649, Expect=0.0]} {Mouse: ENSMUSG00000112449, Srp54b, signal recognition particle 54B, [Score=650, Expect=0.0]; ENSMUSG00000073079, Srp54a, signal recognition particle 54A, [Score=650, Expect=0.0]; ENSMUSG00000079108, Srp54c, signal recognition particle 54C, [Score=647, Expect=0.0]} {Dmel: FBgn0010747, Srp54k, Signal recognition particle protein 54k, [Score=613, Expect=0.0]} {Celegans: WBGene00009012, F21D5.7, Signal recognition particle 54 kDa protein, [Score=620, Expect=0.0]} {Smed: dd_Smed_v6_2045_1_1, dd_Smed_v6_2045_1_1, [Score=624, Expect=0.0]} {RNA1509_42748} {RNA1310_18797, RNA1509_42748} {RNA1509_42748, RNA815_14281}
88. MligTC455_51747 32 0.66 Mlig455_019791, Mlig455_019810

Neo: -

Age: -

1.684 - - - - 0.734 0.950

Mlig455_019791 {REF} {Length: 1662} {tRNA: Undet(NNN),pseudo, score=21.8} {RNA1509_26806} {RNA1310_54539} {RNA815_44342}

Mlig455_019810 {REF} {Length: 1680} {tRNA: Undet(NNN),pseudo, score=20.2} {RNA1509_45595} {RNA1310_54539} {RNA815_44342}
89. MligTC455_19040 49 1.03 Mlig455_003437

Neo: -

Age: -

Region-enriched R2: 6.133/0.00615
Region-enriched R3: 4.021/0.03085

CAV1 1.679 - - - 0.721 - 0.958 Mlig455_003437 {REF} {Length: 808} {Pfam: Caveolin [PF01146.19, score=118.3]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=101, Expect=7e-28]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=102, Expect=2e-28]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.6, Expect=9e-17]} {Smed: dd_Smed_v6_13481_0_1, dd_Smed_v6_13481_0_1, [RH, Score=142, Expect=8e-45]} {RNA1509_53381} {RNA1310_97043} {RNA815_32565}
90. MligTC455_19041 54 1.12 Mlig455_030662

Neo: -

Age: -

Region-enriched R2: 9.337/0.00002
Region-enriched R3: 6.044/0.00168

CAV1 1.679 - - - - 0.717 0.962 Mlig455_030662 {REF} {Length: 940} {Pfam: Caveolin [PF01146.19, score=117.8]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=98.2, Expect=1e-26]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=99.4, Expect=3e-27]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [Score=73.9, Expect=6e-17]} {Smed: dd_Smed_v6_6535_0_1, dd_Smed_v6_6535_0_1, [RH, Score=133, Expect=6e-41]} {RNA1509_53325} {RNA1310_97043} {RNA815_32565}
91. MligTC455_50676 3764 78.41 Mlig455_024344

Neo: -

Age: -

IQCD 1.675 - 0.715 - - 0.960 - Mlig455_024344 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_1833, RNA1509_46413} {RNA1310_4220.1, RNA1509_46413} {RNA1509_46413, RNA815_1223.1}
92. MligTC455_49015 2886 60.13 Mlig455_019168

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.204

PPP1R32 1.671 - - - 0.716 0.955 - Mlig455_019168 {REF} {Length: 1846} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 32 [PF15691.7, score=381.2]} {Human: ENSG00000162148, PPP1R32, protein phosphatase 1 regulatory subunit 32, [RH, Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000035179, Ppp1r32, protein phosphatase 1, regulatory subunit 32, [RH, Score=150, Expect=2e-40]} {Smed: dd_Smed_v6_6404_0_1, dd_Smed_v6_6404_0_1, [RH, Score=263, Expect=2e-83]} {RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1310_15371.1, RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1509_2656, RNA1509_42026, RNA1509_47496, RNA815_5915}
93. MligTC455_50677 3742 77.95 Mlig455_024461

Neo: -

Age: -

IQCD 1.666 - 0.701 - - 0.965 - Mlig455_024461 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1310_4220.1, RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931, RNA815_1223.1}
94. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

CNTRL 1.665 - - - 0.703 0.962 -

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
95. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

FLNB 1.664 - - 0.704 - 0.960 -

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
96. MligTC455_21323 1708 35.59 Mlig455_017330

Neo: -

Age: Down-Up-Up

RIIAD1 1.651 - - - 0.701 0.950 - Mlig455_017330 {REF} {Length: 587} {TRANSSPLICED} {Human: ENSG00000178796, RIIAD1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=86.7, Expect=6e-23]} {Mouse: ENSMUSG00000028139, Riiad1, regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1, [RH, Score=87.4, Expect=5e-23]} {Smed: dd_Smed_v6_4716_0_2, dd_Smed_v6_4716_0_2, [RH, Score=124, Expect=8e-38]} {RNA1509_4188} {RNA1310_57362} {RNA815_29384.1}
97. MligTC455_41182 1050 21.88 Mlig455_052867

Neo: -

Age: logFC(26M/2M)=-0.253

Region-enriched R4: 1.306/0.04107

AK5 0.987 - - - - 0.987 - Mlig455_052867 {REF} {Length: 2821} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=105.1]; AAA domain [PF13207.8, score=87.7]; AAA domain [PF13238.8, score=49.8]; AAA domain [PF13671.8, score=35.5]; IQ calmodulin-binding motif [PF00612.29, score=34.4]; AAA ATPase domain [PF13191.8, score=29.0]; AAA domain [PF13521.8, score=21.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.5]; AAA domain [PF13245.8, score=19.8]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [RH, Score=223, Expect=9e-64]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [RH, Score=222, Expect=1e-63]} {Dmel: FBgn0032083, CG9541, [RH, Score=108, Expect=2e-24]} {Celegans: WBGene00008746, F13E6.2, [Score=127, Expect=4e-30]} {Smed: dd_Smed_v6_5119_0_1, dd_Smed_v6_5119_0_1, [RH, Score=266, Expect=9e-78]} {RNA1509_8959} {RNA1310_6179.1, RNA1509_8959} {RNA1509_8959, RNA815_3037}
98. MligTC455_34564 216 4.51 Mlig455_045027

Neo: -

Age: -

VASH1 0.984 - - - - 0.984 - Mlig455_045027 {REF} {Length: 1457} {Pfam: Vasohibin [PF14822.8, score=320.1]} {Human: ENSG00000071246, VASH1, vasohibin 1, [RH, Score=258, Expect=2e-83]; ENSG00000143494, VASH2, vasohibin 2, [RH, Score=256, Expect=7e-83]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=261, Expect=7e-85]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=254, Expect=2e-82]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=233, Expect=4e-75]} {RNA1509_59274} {RNA1310_23626.1} {RNA815_21188.1}
99. MligTC455_29077 338 7.03 Mlig455_031356, Mlig455_031357

Neo: -

Age: -

0.981 - - - - - 0.981

Mlig455_031356 {REF} {Length: 2138} {RNA1509_35450} {RNA1310_12556.2} {RNA815_5170.1}

Mlig455_031357 {REF} {Length: 2357} {NoTransDecoderORF} {RNA1509_54862} {RNA1310_63.1} {RNA815_5170.1}
100. MligTC455_38072 222 4.62 Mlig455_012098, Mlig455_023289, Mlig455_023290, Mlig455_030139

Neo: -

Age: -

0.978 - - - - 0.978 -

Mlig455_012098 {REF} {Length: 3878} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_023289 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_57501} {RNA1310_60087} {RNA815_63886}

Mlig455_023290 {REF} {Length: 660} {RNA1509_44389} {RNA1310_27455} {RNA815_10592}

Mlig455_030139 {REF} {Length: 465} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

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