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Results for MligTC455_45835

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

MAPK15

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Cumulative graph for MligTC455_45835

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.629 5.669 0.04095 0.49127
RegionR2 0.777 5.669 0.01824 0.14443
RegionR3 0.358 5.669 0.19509 0.73331
RegionR4 0.336 5.669 0.31961 0.63619
RegionR5 -0.013 5.669 0.96477 1.00000
RegionR6 0.191 5.669 0.50313 1.00000
RegionR7 0.104 5.669 0.75355 1.00000
RegionR8 -0.124 5.669 0.76030 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.572 5.669 0.66882 1.00000
RegenerationR2 0.203 5.669 0.48225 0.86434
RegenerationR3 0.063 5.669 0.84275 0.99540
RegenerationR4 0.037 5.669 0.91351 1.00000
RegenerationR5 -0.363 5.669 0.24843 0.68208
RegenerationR6 -0.46 5.669 0.16702 0.49766
RegenerationBL -0.098 5.669 0.77021 1.00000
RegenerationTP -0.744 5.669 0.06137 0.40128


Genes with expression patterns similar to MligTC455_45835

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

MAPK15 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
2. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

XRRA1 4.171 0.840 0.704 - 0.819 0.981 0.827 Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
3. MligTC455_15346 10495 218.65 Mlig455_014073, Mlig455_014091

Neo: -

Age: -

TEKT4 3.477 - 0.736 0.874 - 0.957 0.910

Mlig455_014073 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=471.5]; Intermediate filament protein [PF00038.23, score=20.4]} {Human: ENSG00000163060, TEKT4, tektin 4, [RH, Score=404, Expect=3e-138]} {Mouse: ENSMUSG00000024175, Tekt4, tektin 4, [RH, Score=419, Expect=2e-144]} {Dmel: FBgn0028902, Tektin-A, Tektin A, [RH, Score=219, Expect=3e-65]} {Smed: dd_Smed_v6_4872_0_1, dd_Smed_v6_4872_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_689} {RNA1310_17094.1} {RNA815_4941}

Mlig455_014091 {REF} {Length: 1995} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=471.5]; Intermediate filament protein [PF00038.23, score=20.4]} {Human: ENSG00000163060, TEKT4, tektin 4, [RH, Score=404, Expect=3e-138]} {Mouse: ENSMUSG00000024175, Tekt4, tektin 4, [RH, Score=419, Expect=2e-144]} {Dmel: FBgn0028902, Tektin-A, Tektin A, [RH, Score=219, Expect=3e-65]} {Smed: dd_Smed_v6_4872_0_1, dd_Smed_v6_4872_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416} {RNA1310_17094.1, RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416} {RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416, RNA815_4941}
4. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

CCDC39 3.464 - - 0.862 0.845 0.981 0.776 Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
5. MligTC455_20009 4606 95.96 Mlig455_038152, Mlig455_038257

Neo: -

Age: -

Region-enriched R4: 1.035/0.02931

3.409 - - 0.820 0.742 0.967 0.880

Mlig455_038152 {REF} {Length: 1064} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [RH, Score=94.7, Expect=3e-26]} {RNA1509_10830, RNA1509_16892} {RNA1310_37711, RNA1509_10830} {RNA1509_10830, RNA815_18837}

Mlig455_038257 {REF} {Length: 2711} {Smed: dd_Smed_v6_8141_0_1, dd_Smed_v6_8141_0_1, [RH, Score=94.7, Expect=3e-26]} {RNA1509_16892, RNA1509_40689} {RNA1310_37711, RNA1509_16892, RNA1509_40689} {RNA1509_16892, RNA1509_40689, RNA815_18837}
6. MligTC455_49596 1668 34.74 Mlig455_063375

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R2: 1.067/0.02988

ARMC4 3.375 - 0.778 - 0.881 0.958 0.758 Mlig455_063375 {REF} {Length: 3432} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=192.9]; HEAT repeats [PF13646.8, score=53.0]; Armadillo-like [PF04826.15, score=26.7]; V-ATPase subunit H [PF11698.10, score=26.4]; HEAT-like repeat [PF13513.8, score=26.1]; Kinesin-associated protein (KAP) [PF05804.14, score=24.7]; V-ATPase subunit H [PF03224.16, score=23.0]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=22.2]; HEAT repeat [PF02985.24, score=19.6]} {Human: ENSG00000169126, ARMC4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Mouse: ENSMUSG00000061802, Armc4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Dmel: FBgn0031905, gudu, [RH, Score=592, Expect=0.0]} {Smed: dd_Smed_v6_5065_0_1, dd_Smed_v6_5065_0_1, [RH, Score=932, Expect=0.0]} {RNA1509_1009, RNA1509_21601} {RNA1310_2954.1, RNA1509_1009, RNA1509_21601} {RNA1509_1009, RNA1509_21601, RNA815_1045}
7. MligTC455_44849 3056 63.66 Mlig455_014245

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

LEXM 3.352 - 0.741 0.905 - 0.972 0.734 Mlig455_014245 {REF} {Length: 2724} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1} {RNA815_5377}
8. MligTC455_50676 3764 78.41 Mlig455_024344

Neo: -

Age: -

IQCD 3.314 - 0.741 0.791 - 0.967 0.815 Mlig455_024344 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_1833, RNA1509_46413} {RNA1310_4220.1, RNA1509_46413} {RNA1509_46413, RNA815_1223.1}
9. MligTC455_50677 3742 77.95 Mlig455_024461

Neo: -

Age: -

IQCD 3.301 - 0.725 0.784 - 0.970 0.822 Mlig455_024461 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1310_4220.1, RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931, RNA815_1223.1}
10. MligTC455_16955 1687 35.15 Mlig455_051000

Neo: -

Age: Down-Up-Up

PLA2G7 3.284 0.726 0.778 - 0.806 0.974 - Mlig455_051000 {REF} {Length: 1559} {TRANSSPLICED} {Pfam: Platelet-activating factor acetylhydrolase, isoform II [PF03403.15, score=213.8]; alpha/beta hydrolase fold [PF00561.22, score=28.3]; Alpha/beta hydrolase family [PF12697.9, score=26.6]; Serine aminopeptidase, S33 [PF12146.10, score=25.3]; Chlorophyllase enzyme [PF12740.9, score=20.4]} {Human: ENSG00000146070, PLA2G7, phospholipase A2 group VII, [RH, Score=171, Expect=1e-48]} {Mouse: ENSMUSG00000037366, Pafah2, platelet-activating factor acetylhydrolase 2, [RH, Score=163, Expect=5e-46]; ENSMUSG00000023913, Pla2g7, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), [RH, Score=158, Expect=1e-43]} {Celegans: WBGene00003906, paf-1, PAF-1; PAF-acetylhydrolase, [RH, Score=142, Expect=2e-38]} {RNA1509_16678, RNA1509_21980} {RNA1310_21439.1, RNA1509_16678, RNA1509_21980} {RNA1509_16678, RNA1509_21980, RNA815_19873}
11. MligTC455_42242 1575 32.81 Mlig455_039054

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.378

PLXDC1 3.253 - 0.753 0.823 0.719 0.958 - Mlig455_039054 {REF} {Length: 2567} {Human: ENSG00000161381, PLXDC1, plexin domain containing 1, [Score=109, Expect=1e-25]; ENSG00000120594, PLXDC2, plexin domain containing 2, [Score=107, Expect=7e-25]} {Mouse: ENSMUSG00000017417, Plxdc1, plexin domain containing 1, [Score=111, Expect=3e-26]; ENSMUSG00000026748, Plxdc2, plexin domain containing 2, [Score=107, Expect=1e-24]} {Dmel: FBgn0028331, l(1)G0289, lethal (1) G0289, [Score=97.8, Expect=1e-21]} {Celegans: WBGene00007982, pxd-1, PleXin Domain containing, [Score=112, Expect=6e-27]} {Smed: dd_Smed_v6_68203_0_1, dd_Smed_v6_68203_0_1, [Score=69.7, Expect=3e-14]} {RNA1509_49412, RNA1509_59319, RNA1509_8427} {RNA1310_7172.1, RNA1509_49412, RNA1509_59319} {RNA1509_49412, RNA1509_59319, RNA815_7707}
12. MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

3.186 - 0.727 0.732 - 0.973 0.754

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}
13. MligTC455_32937 681 14.18 Mlig455_039443

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.822

2.662 - - 0.850 - 0.969 0.843 Mlig455_039443 {REF} {Length: 1676} {RNA1509_14386} {RNA1310_21532, RNA1509_14386} {RNA1509_14386, RNA815_8850}
14. MligTC455_29373 3437 71.6 Mlig455_034659

Neo: -

Age: -

2.614 - - 0.892 0.755 0.967 - Mlig455_034659 {REF} {Length: 1882} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}
15. MligTC455_37361 5370 111.88 Mlig455_043035

Neo: -

Age: logFC(26M/2M)=-0.378

CFAP52 2.607 - 0.765 0.879 - 0.963 - Mlig455_043035 {REF} {Length: 2490} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.1]; WD40-like domain [PF17005.7, score=27.1]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=441, Expect=1e-145]} {Celegans: WBGene00004895, smu-1, SMU-1; Suppressor of Mec and Unc defects, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=841, Expect=0.0]} {RNA1509_1341} {RNA1310_8859, RNA1509_1341} {RNA1509_1341, RNA815_2855}
16. MligTC455_37360 5178 107.87 Mlig455_043000

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.956

CFAP52 2.601 - 0.758 0.877 - 0.966 - Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855}
17. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

VASH2 2.596 - - - 0.776 0.959 0.861 Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
18. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

TTC16 2.594 - - 0.811 - 0.952 0.831 Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
19. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

CNTRL 2.589 - - 0.799 0.836 0.954 -

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
20. MligTC455_53211 1358 28.3 Mlig455_040065, Mlig455_040091

Neo: -

Age: logFC(26M/2M)=-0.362

Region-enriched R4: 1.888/0.01442

2.584 - - - 0.868 0.961 0.755

Mlig455_040065 {REF} {Length: 3189} {RNA1509_49542, RNA1509_9168} {RNA1310_8796.1, RNA1509_49542, RNA1509_9168} {RNA1509_49542, RNA1509_9168, RNA815_3100}

Mlig455_040091 {REF} {Length: 2759} {RNA1509_39791, RNA1509_9168} {RNA1310_8796.1, RNA1509_39791} {RNA1509_39791, RNA815_3100}
21. MligTC455_43766 2863 59.66 Mlig455_001907

Neo: -

Age: logFC(26M/2M)=-0.394

EFHB 2.556 - - - 0.801 0.974 0.781 Mlig455_001907 {REF} {Length: 2219} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=45.4]; EF hand [PF00036.34, score=42.6]; EF-hand domain [PF13405.8, score=40.6]; Family of unknown function (DUF5580) [PF17743.3, score=32.4]; EF hand [PF13202.8, score=31.5]; EF-hand domain pair [PF13833.8, score=19.0]} {Human: ENSG00000163576, EFHB, EF-hand domain family member B, [Score=361, Expect=9e-117]} {Mouse: ENSMUSG00000023931, Efhb, EF hand domain family, member B, [Score=332, Expect=2e-104]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=53.5, Expect=6e-08]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=52.4, Expect=8e-08]} {Smed: dd_Smed_v6_11909_0_1, dd_Smed_v6_11909_0_1, [Score=325, Expect=5e-105]} {RNA1509_2205} {RNA1310_7693, RNA1509_2205} {RNA1509_2205, RNA815_3913}
22. MligTC455_49015 2886 60.13 Mlig455_019168

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.204

PPP1R32 2.551 - 0.774 - - 0.956 0.821 Mlig455_019168 {REF} {Length: 1846} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 32 [PF15691.7, score=381.2]} {Human: ENSG00000162148, PPP1R32, protein phosphatase 1 regulatory subunit 32, [RH, Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000035179, Ppp1r32, protein phosphatase 1, regulatory subunit 32, [RH, Score=150, Expect=2e-40]} {Smed: dd_Smed_v6_6404_0_1, dd_Smed_v6_6404_0_1, [RH, Score=263, Expect=2e-83]} {RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1310_15371.1, RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1509_2656, RNA1509_42026, RNA1509_47496, RNA815_5915}
23. MligTC455_53471 1325 27.61 Mlig455_015629

Neo: -

Age: logFC(26M/2M)=-0.386

CFAP65 2.551 - - 0.730 - 0.956 0.865 Mlig455_015629 {REF} {Length: 5817} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=93.0]; MSP (Major sperm protein) domain [PF00635.28, score=47.3]; Protein of unknown function (DUF1573) [PF07610.13, score=22.4]; Transmembrane protein 131-like N-terminal [PF12371.10, score=21.0]} {Human: ENSG00000181378, CFAP65, cilia and flagella associated protein 65, [RH, Score=850, Expect=0.0]} {Mouse: ENSMUSG00000047021, Cfap65, cilia and flagella associated protein 65, [RH, Score=844, Expect=0.0]} {Smed: dd_Smed_v6_12428_0_1, dd_Smed_v6_12428_0_1, [RH, Score=1276, Expect=0.0]} {RNA1509_19700} {RNA1310_760, RNA1509_19700} {RNA1509_19700, RNA815_222.1}
24. MligTC455_47476 7650 159.38 Mlig455_011139

Neo: -

Age: logFC(26M/2M)=-0.342

RSPH1 2.534 - - 0.798 0.764 0.972 - Mlig455_011139 {REF} {Length: 1427} {Pfam: MORN repeat [PF02493.22, score=123.5]} {Human: ENSG00000160188, RSPH1, radial spoke head component 1, [RH, Score=256, Expect=6e-84]} {Mouse: ENSMUSG00000024033, Rsph1, radial spoke head 1 homolog (Chlamydomonas), [RH, Score=266, Expect=8e-88]} {Dmel: FBgn0032478, CG5458, [RH, Score=149, Expect=6e-42]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=59.3, Expect=1e-09]} {Smed: dd_Smed_v6_3321_0_1, dd_Smed_v6_3321_0_1, [RH, Score=306, Expect=6e-104]} {RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1310_22398, RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1509_10402, RNA1509_5779, RNA1509_6982, RNA815_10865}
25. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

DST 2.524 0.823 - - 0.735 0.966 - Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}
26. MligTC455_43767 1310 27.29 Mlig455_048807

Neo: -

Age: Down-Down-Up

EFHB 2.521 - - - 0.787 0.958 0.776 Mlig455_048807 {REF} {Length: 2201} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=45.4]; EF hand [PF00036.34, score=42.2]; EF-hand domain [PF13405.8, score=40.2]; Family of unknown function (DUF5580) [PF17743.3, score=32.2]; EF hand [PF13202.8, score=31.1]; EF-hand domain pair [PF13833.8, score=18.8]} {Human: ENSG00000163576, EFHB, EF-hand domain family member B, [RH, Score=386, Expect=1e-125]} {Mouse: ENSMUSG00000023931, Efhb, EF hand domain family, member B, [RH, Score=359, Expect=7e-114]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=53.1, Expect=6e-08]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=52.8, Expect=7e-08]} {Smed: dd_Smed_v6_11909_0_1, dd_Smed_v6_11909_0_1, [RH, Score=351, Expect=3e-114]} {RNA1509_2205} {RNA1310_7693} {RNA815_3913}
27. MligTC455_29452 881 18.34 Mlig455_044747

Neo: -

Age: -

LMNTD1 2.516 - - - 0.743 0.954 0.819 Mlig455_044747 {REF} {Length: 9990} {tRNA: Phe(GAA), score=86.5} {Pfam: Intermediate filament protein [PF00038.23, score=53.6]; Lamin Tail Domain [PF00932.21, score=40.3]; Mechanosensitive ion channel porin domain [PF12795.9, score=20.9]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=146, Expect=3e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=3e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [Score=208, Expect=5e-56]} {RNA1509_20212} {RNA1310_1500.1} {RNA815_1147.1}
28. MligTC455_52118 5757 119.94 Mlig455_069122

Neo: -

Age: logFC(26M/2M)=0.892

CFAP58 2.507 - - 0.780 0.753 0.974 - Mlig455_069122 {REF} {Length: 3136} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=23.0]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=923, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=991, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=1e-40]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1103, Expect=0.0]} {RNA1509_282} {RNA1310_4570, RNA1509_282} {RNA1509_282, RNA815_1528}
29. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

LMNTD1 2.506 - - - 0.732 0.952 0.822 Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
30. MligTC455_33364 348 7.24 Mlig455_009410, Mlig455_016109, Mlig455_026502, Mlig455_027903, Mlig455_036913, Mlig455_066713, Mlig455_068644, Mlig455_070501

Neo: -

Age: logFC(26M/2M)=-0.641

NYNRIN 2.483 - - 0.744 - 0.969 0.770

Mlig455_009410 {REF} {Length: 6826} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=304.8]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=92.4, Expect=4e-20]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=209, Expect=1e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=301, Expect=1e-97]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_016109 {REF} {Length: 3482} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.5]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.8]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=55.7]; Aspartyl protease [PF13650.8, score=21.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=7e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=124, Expect=4e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=425, Expect=7e-131]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}

Mlig455_026502 {REF} {Length: 698} {Pfam: Zinc knuckle [PF00098.25, score=27.8]} {RNA1509_38652} {RNA1310_25149.1} {RNA815_13280}

Mlig455_027903 {REF} {Length: 3748} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.7]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=51.2]; Aspartyl protease [PF13650.8, score=21.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=121, Expect=5e-27]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=122, Expect=1e-27]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=432, Expect=8e-134]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_036913 {REF} {Length: 639} {RNA1509_48973} {RNA1310_39833} {RNA815_36286}

Mlig455_066713 {REF} {Length: 2873} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=122.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.1]; Integrase zinc binding domain [PF17921.3, score=77.1]; Integrase core domain [PF00665.28, score=53.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=117, Expect=3e-26]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=117, Expect=4e-26]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=237, Expect=1e-65]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_068644 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.2]; Integrase zinc binding domain [PF17921.3, score=79.7]; Integrase core domain [PF00665.28, score=49.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=130, Expect=4e-30]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=6e-29]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=313, Expect=5e-93]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_070501 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=123.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.2]; Integrase zinc binding domain [PF17921.3, score=76.5]; Integrase core domain [PF00665.28, score=54.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=2e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=1e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=322, Expect=2e-96]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}
31. MligTC455_23078 287 5.98 Mlig455_011747

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.620

CUBN 2.482 0.797 - 0.706 - 0.979 - Mlig455_011747 {REF} {Length: 2191} {Pfam: EGF-like domain [PF00008.29, score=33.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=52.4, Expect=2e-07]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=53.9, Expect=3e-08]} {RNA1509_38266} {RNA1310_23149} {RNA815_9585.1}
32. MligTC455_47868 5452 113.57 Mlig455_031216

Neo: -

Age: logFC(26M/2M)=-0.277

TEKT1 2.479 - - 0.716 0.804 0.959 - Mlig455_031216 {REF} {Length: 1751} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=439.2]} {Human: ENSG00000167858, TEKT1, tektin 1, [RH, Score=379, Expect=4e-129]} {Mouse: ENSMUSG00000020799, Tekt1, tektin 1, [RH, Score=373, Expect=9e-127]} {Dmel: FBgn0052820, CG32820, [Score=217, Expect=4e-65]} {Smed: dd_Smed_v6_3287_0_2, dd_Smed_v6_3287_0_2, [RH, Score=448, Expect=1e-156]} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1310_15062.1, RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215, RNA815_6688}
33. MligTC455_54125 957 19.94 Mlig455_000017

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.528/0.00489

SPEF1 2.476 - 0.743 - 0.776 0.957 - Mlig455_000017 {REF} {Length: 1279} {TRANSSPLICED} {Pfam: CH-like domain in sperm protein [PF06294.13, score=114.7]; CAMSAP CH domain [PF11971.10, score=53.6]} {Human: ENSG00000101222, SPEF1, sperm flagellar 1, [RH, Score=172, Expect=1e-52]} {Mouse: ENSMUSG00000027329, Spef1, sperm flagellar 1, [RH, Score=180, Expect=3e-56]} {Dmel: FBgn0030722, CG12395, [Score=65.5, Expect=2e-12]} {Smed: dd_Smed_v6_5648_0_1, dd_Smed_v6_5648_0_1, [RH, Score=272, Expect=5e-93]} {RNA1509_17511, RNA1509_37707, RNA1509_9365} {RNA1310_25346.1, RNA1509_17511, RNA1509_37707, RNA1509_9365} {RNA1509_17511, RNA1509_37707, RNA1509_9365, RNA815_11607}
34. MligTC455_38958 335 6.98 Mlig455_068315

Neo: -

Age: -

2.453 - - - 0.754 0.952 0.747 Mlig455_068315 {REF} {Length: 2665} {Pfam: EF-hand domain [PF13405.8, score=31.1]; EF-hand domain pair [PF13499.8, score=27.3]; EF hand [PF00036.34, score=22.7]} {Mouse: ENSMUSG00000030321, Efcab12, EF-hand calcium binding domain 12, [RH, Score=65.1, Expect=2e-10]} {Smed: dd_Smed_v6_10608_0_1, dd_Smed_v6_10608_0_1, [RH, Score=57.8, Expect=7e-10]} {RNA1509_20232} {RNA1310_17116} {RNA815_14272}
35. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

FLNB 2.451 - - 0.742 0.741 0.968 -

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
36. MligTC455_50996 449 9.36 Mlig455_002019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.319

Region-enriched R2: 1.520/0.04245

TRIM71 2.432 - - 0.742 - 0.967 0.723 Mlig455_002019 {REF} {Length: 2281} {Pfam: NHL repeat [PF01436.23, score=74.6]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=79.3, Expect=3e-15]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=76.3, Expect=3e-14]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=79.7, Expect=2e-15]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=76.3, Expect=2e-14]} {Dmel: FBgn0265356, tn, thin, [Score=94.0, Expect=3e-20]} {Celegans: WBGene00003026, lin-41, [Score=80.5, Expect=5e-16]} {Smed: dd_Smed_v6_13659_0_1, dd_Smed_v6_13659_0_1, [RH, Score=102, Expect=2e-24]} {RNA1509_17378} {RNA1310_19512.1, RNA1509_17378} {RNA1509_17378, RNA815_7968}
37. MligTC455_41727 782 16.28 Mlig455_060039

Neo: -

Age: -

KATNAL2 2.425 - 0.714 - 0.743 0.968 - Mlig455_060039 {REF} {Length: 2577} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=126.6]; AAA+ lid domain [PF17862.3, score=47.1]; LisH [PF08513.13, score=26.5]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=22.3]; AAA ATPase domain [PF13191.8, score=19.6]; TIP49 P-loop domain [PF06068.15, score=19.1]; AAA domain (dynein-related subfamily) [PF07728.16, score=18.8]} {Human: ENSG00000167216, KATNAL2, katanin catalytic subunit A1 like 2, [RH, Score=606, Expect=0.0]} {Mouse: ENSMUSG00000025420, Katnal2, katanin p60 subunit A-like 2, [RH, Score=608, Expect=0.0]} {Dmel: FBgn0040208, Kat60, Katanin 60, [Score=279, Expect=5e-86]} {Celegans: WBGene00003183, mei-1, Meiotic spindle formation protein mei-1, [Score=261, Expect=3e-80]} {Smed: dd_Smed_v6_14853_0_1, dd_Smed_v6_14853_0_1, [RH, Score=646, Expect=0.0]} {RNA1509_14139} {RNA1310_9263.1} {RNA815_5637}
38. MligTC455_18479 293 6.11 Mlig455_029348

Neo: -

Age: -

Region-enriched R2: 2.256/0.00988

1.881 - - - - 0.966 0.915 Mlig455_029348 {REF} {Length: 2771} {Pfam: Leucine Rich repeat [PF13516.8, score=43.0]} {Mouse: ENSMUSG00000099564, Gm28729, predicted gene 28729, [RH, Score=125, Expect=4e-31]} {Smed: dd_Smed_v6_16437_0_1, dd_Smed_v6_16437_0_1, [RH, Score=268, Expect=2e-84]} {RNA1509_18255, RNA1509_55057} {RNA1310_16954, RNA1509_18255, RNA1509_55057} {RNA1509_18255, RNA1509_55057, RNA815_6360}
39. MligTC455_16051 3672 76.49 Mlig455_051486

Neo: -

Age: Down-Down-Up

NUDT9 1.854 - 0.881 - - 0.973 - Mlig455_051486 {REF} {Length: 1822} {TRANSSPLICED} {Pfam: NUDIX domain [PF00293.30, score=22.9]} {Human: ENSG00000170502, NUDT9, nudix hydrolase 9, [RH, Score=278, Expect=8e-92]} {Mouse: ENSMUSG00000029310, Nudt9, nudix (nucleoside diphosphate linked moiety X)-type motif 9, [RH, Score=281, Expect=4e-93]} {Dmel: FBgn0036648, CG4098, [RH, Score=258, Expect=1e-84]} {Celegans: WBGene00003583, ndx-6, Putative nudix hydrolase 6, [RH, Score=214, Expect=2e-68]} {Smed: dd_Smed_v6_1143_0_1, dd_Smed_v6_1143_0_1, [RH, Score=293, Expect=1e-98]} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_4802, RNA1509_51897} {RNA1310_32536, RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897, RNA815_11473.1}
40. MligTC455_44113 3565 74.27 Mlig455_032730, Mlig455_032753

Neo: -

Age: -

CFAP97 1.84 - - - - 0.871 0.969

Mlig455_032730 {REF} {Length: 2200} {Pfam: Hemingway/CFA97 [PF13879.8, score=36.8]} {Human: ENSG00000164323, CFAP97, cilia and flagella associated protein 97, [RH, Score=73.6, Expect=2e-13]} {Mouse: ENSMUSG00000031631, Cfap97, cilia and flagella associated protein 97, [RH, Score=73.6, Expect=1e-13]} {RNA1509_4299} {RNA1310_12911, RNA1509_4299} {RNA1509_4299, RNA815_4525.1}

Mlig455_032753 {REF} {Length: 2143} {Pfam: Hemingway/CFA97 [PF13879.8, score=36.8]} {Human: ENSG00000164323, CFAP97, cilia and flagella associated protein 97, [RH, Score=75.5, Expect=4e-14]} {Mouse: ENSMUSG00000031631, Cfap97, cilia and flagella associated protein 97, [RH, Score=75.5, Expect=3e-14]} {RNA1509_4299} {RNA1310_12911} {RNA815_4525.1}
41. MligTC455_44850 2381 49.6 Mlig455_014259

Neo: -

Age: logFC(26M/2M)=-0.355

LEXM 1.836 - - 0.880 - 0.956 - Mlig455_014259 {REF} {Length: 2739} {Human: ENSG00000162398, LEXM, lymphocyte expansion molecule, [RH, Score=169, Expect=2e-47]} {Mouse: ENSMUSG00000054362, Lexm, lymphocyte expansion molecule, [RH, Score=173, Expect=3e-49]} {Smed: dd_Smed_v6_10776_0_1, dd_Smed_v6_10776_0_1, [RH, Score=361, Expect=3e-122]} {RNA1509_2011} {RNA1310_14442.1, RNA1509_2011} {RNA1509_2011, RNA815_5377}
42. MligTC455_32519 147 3.06 Mlig455_017549

Neo: -

Age: logFC(26M/2M)=-0.495

NWD2 1.805 - - - - 0.965 0.840 Mlig455_017549 {REF} {Length: 6334} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA ATPase domain [PF13191.8, score=38.4]; NACHT domain [PF05729.14, score=34.5]; AAA domain [PF13481.8, score=20.7]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=347, Expect=8e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=340, Expect=1e-96]} {Dmel: FBgn0038397, CG10185, [Score=472, Expect=9e-143]} {Celegans: WBGene00020254, T05C3.2, [Score=527, Expect=1e-162]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=380, Expect=2e-110]} {RNA1509_23488} {RNA1310_497.1} {RNA815_237}
43. MligTC455_46850 265 5.52 Mlig455_005746

Neo: -

Age: -

Region-enriched R4: 2.659/0.01708

1.803 - - - 0.835 0.968 - Mlig455_005746 {REF} {Length: 3392} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=84.7, Expect=3e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=68.9, Expect=1e-11]} {RNA1509_46369, RNA1509_7522} {RNA1310_3662, RNA1509_46369, RNA1509_7522} {RNA1509_46369, RNA1509_7522, RNA815_5689}
44. MligTC455_44836 330 6.88 Mlig455_002007, Mlig455_002209

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.455

TRIM2, TRIM3 1.801 - - - - 0.958 0.843

Mlig455_002007 {REF} {Length: 3003} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=60.9]; 6-bladed beta-propeller [PF17170.6, score=32.1]; B-box zinc finger [PF00643.26, score=30.2]} {Human: ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=132, Expect=4e-31]; ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=132, Expect=4e-31]; ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=128, Expect=9e-30]} {Mouse: ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=132, Expect=3e-31]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=132, Expect=2e-31]} {Dmel: FBgn0265356, tn, thin, [Score=102, Expect=6e-22]} {Celegans: WBGene00003026, lin-41, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_26017_0_1, dd_Smed_v6_26017_0_1, [Score=63.5, Expect=2e-10]} {RNA1509_19290} {RNA1310_4861.1} {RNA815_7213.1}

Mlig455_002209 {REF} {Length: 3098} {Pfam: NHL repeat [PF01436.23, score=60.5]; 6-bladed beta-propeller [PF17170.6, score=37.8]; B-box zinc finger [PF00643.26, score=30.2]} {Human: ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=134, Expect=1e-31]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=134, Expect=1e-31]; ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=131, Expect=1e-30]} {Mouse: ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=134, Expect=6e-32]; ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=134, Expect=9e-32]} {Dmel: FBgn0265356, tn, thin, [Score=105, Expect=1e-22]} {Celegans: WBGene00003026, lin-41, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_26017_0_1, dd_Smed_v6_26017_0_1, [Score=66.2, Expect=2e-11]} {RNA1509_19290} {RNA1310_4861.1} {RNA815_7213.1}
45. MligTC455_16412 403 8.39 Mlig455_048929, Mlig455_048953

Neo: -

Age: Down-Up-Up

MAP3K2 1.786 - - - - 0.959 0.827

Mlig455_048929 {REF} {Length: 2311} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=216.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=149.9]; Kinase-like [PF14531.8, score=28.8]; Fungal protein kinase [PF17667.3, score=20.0]; ABC1 atypical kinase-like domain [PF03109.18, score=18.7]} {Human: ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [Score=238, Expect=3e-71]; ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=234, Expect=3e-69]} {Mouse: ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [Score=241, Expect=2e-72]; ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=233, Expect=3e-69]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=161, Expect=3e-42]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=167, Expect=3e-45]} {Smed: dd_Smed_v6_6304_0_1, dd_Smed_v6_6304_0_1, [RH, Score=177, Expect=2e-52]} {RNA1509_12704} {RNA1310_14266} {RNA815_4624.1}

Mlig455_048953 {REF} {Length: 2666} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=217.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=150.2]; Kinase-like [PF14531.8, score=30.6]; Fungal protein kinase [PF17667.3, score=20.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.0]} {Human: ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [Score=238, Expect=2e-71]; ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=233, Expect=1e-69]} {Mouse: ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [Score=241, Expect=8e-73]; ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=232, Expect=2e-69]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=162, Expect=1e-42]} {Celegans: WBGene00003822, nsy-1, Mitogen-activated protein kinase kinase kinase nsy-1, [Score=169, Expect=2e-45]} {Smed: dd_Smed_v6_6304_0_1, dd_Smed_v6_6304_0_1, [RH, Score=177, Expect=9e-53]} {RNA1509_12704} {RNA1310_14266} {RNA815_4624.1}
46. MligTC455_21956 3873 80.68 Mlig455_016345

Neo: -

Age: -

CFAP52 1.785 - - - - 0.961 0.824 Mlig455_016345 {REF} {Length: 2469} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=46.2]; WD40-like domain [PF17005.7, score=20.0]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=729, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [Score=419, Expect=2e-137]} {Celegans: WBGene00008586, snrp-40.1, [Score=62.8, Expect=2e-10]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=845, Expect=0.0]} {RNA1509_26111, RNA1509_3132, RNA1509_38636} {RNA1310_7679, RNA1509_26111, RNA1509_3132, RNA1509_38636} {RNA1509_26111, RNA1509_3132, RNA1509_38636, RNA815_3001}
47. MligTC455_50432 2499 52.06 Mlig455_053597

Neo: -

Age: -

Region-enriched R8: 1.161/0.01787

ANKRD24 1.784 - - 0.823 - 0.961 - Mlig455_053597 {REF} {Length: 2565} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=56.7]; Ankyrin repeats (3 copies) [PF12796.9, score=56.0]; Ankyrin repeats (many copies) [PF13857.8, score=51.0]; Ankyrin repeat [PF00023.32, score=32.1]; Ankyrin repeat [PF13606.8, score=25.0]} {Human: ENSG00000089847, ANKRD24, ankyrin repeat domain 24, [Score=59.3, Expect=1e-08]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=59.3, Expect=5e-09]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=58.9, Expect=6e-09]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=58.9, Expect=7e-09]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=58.2, Expect=1e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=58.2, Expect=1e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=54.7, Expect=3e-07]} {Celegans: WBGene00006490, kdin-1, KiDINs220 (Vertebrate scaffold protein) homolog, [Score=50.8, Expect=2e-06]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=55.8, Expect=5e-08]} {RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000} {RNA1310_25280, RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000} {RNA1509_10298, RNA1509_17738, RNA1509_28697, RNA1509_34429, RNA1509_40537, RNA1509_8000, RNA815_12634}
48. MligTC455_23589 1204 25.08 Mlig455_013096, Mlig455_013189

Neo: -

Age: -

CNBD1 1.759 - - 0.809 - 0.950 -

Mlig455_013096 {REF} {Length: 1719} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.0]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=213, Expect=2e-63]} {RNA1509_35878} {RNA1310_17903} {RNA815_7217}

Mlig455_013189 {REF} {Length: 1713} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.1]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=212, Expect=5e-63]} {RNA1509_35878} {RNA1310_17903, RNA1509_35878} {RNA1509_35878, RNA815_7217}
49. MligTC455_52157 833 17.35 Mlig455_043477

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.340

Region-enriched R4: 1.399/0.00786

1.758 - - - - 0.950 0.808 Mlig455_043477 {REF} {Length: 2916} {Pfam: Coiled-coil region of CCDC155 or KASH [PF14662.8, score=27.5]; CCDC144C protein coiled-coil region [PF14915.8, score=17.9]} {Smed: dd_Smed_v6_11072_0_1, dd_Smed_v6_11072_0_1, [RH, Score=243, Expect=1e-74]} {RNA1509_23869, RNA1509_39284, RNA1509_5021} {RNA1310_8542.1, RNA1509_23869, RNA1509_39284, RNA1509_5021} {RNA1509_23869, RNA1509_39284, RNA1509_5021, RNA815_2850.1}
50. MligTC455_41702 2176 45.34 Mlig455_055307

Neo: -

Age: Down-Up-Up

CYP2C8 1.757 0.806 - - - 0.951 - Mlig455_055307 {REF} {Length: 2612} {Pfam: Cytochrome P450 [PF00067.24, score=306.8]} {Human: ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=259, Expect=6e-80]} {Mouse: ENSMUSG00000030483, Cyp2b10, cytochrome P450, family 2, subfamily b, polypeptide 10, [Score=257, Expect=2e-79]; ENSMUSG00000040660, Cyp2b9, cytochrome P450, family 2, subfamily b, polypeptide 9, [Score=249, Expect=2e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=247, Expect=2e-75]; ENSMUSG00000040650, Cyp2b23, cytochrome P450, family 2, subfamily b, polypeptide 23, [Score=246, Expect=3e-75]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=246, Expect=1e-74]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=246, Expect=1e-74]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=180, Expect=4e-50]} {Celegans: WBGene00018261, cyp-33C5, CYtochrome P450 family, [Score=221, Expect=7e-66]} {Smed: dd_Smed_v6_2351_0_1, dd_Smed_v6_2351_0_1, [RH, Score=279, Expect=4e-88]} {RNA1509_10256, RNA1509_15694, RNA1509_40717} {RNA1310_11391, RNA1509_10256, RNA1509_15694, RNA1509_40717} {RNA1509_10256, RNA1509_15694, RNA1509_40717, RNA815_585.2}
51. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

GRIA2 1.746 - - - 0.765 0.981 -

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
52. MligTC455_31292 287 5.97 Mlig455_059964

Neo: -

Age: logFC(26M/2M)=-0.518

1.746 - - - 0.782 0.964 - Mlig455_059964 {REF} {Length: 6272} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4549) [PF15082.8, score=142.8]; Ligand-gated ion channel [PF00060.28, score=50.1]} {Mouse: ENSMUSG00000075225, Ccdc162, coiled-coil domain containing 162, [Score=914, Expect=0.0]} {Dmel: FBgn0052704, Ir8a, Ionotropic receptor 8a, [Score=55.5, Expect=5e-07]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [Score=58.2, Expect=6e-08]} {Smed: dd_Smed_v6_16643_0_1, dd_Smed_v6_16643_0_1, [RH, Score=706, Expect=0.0]} {RNA1509_21772} {RNA1310_311.1} {RNA815_144.1}
53. MligTC455_30000 1520 31.66 Mlig455_006409

Neo: -

Age: Down-Down-Up

NOTCH1 1.742 - - - - 0.952 0.790 Mlig455_006409 {REF} {Length: 2677} {TRANSSPLICED} {Pfam: EGF-like domain [PF00008.29, score=198.7]; Human growth factor-like EGF [PF12661.9, score=99.3]; EGF-like domain [PF07974.15, score=23.3]} {Human: ENSG00000148400, NOTCH1, notch 1, [Score=306, Expect=2e-87]; ENSG00000134250, NOTCH2, notch 2, [Score=305, Expect=5e-87]} {Mouse: ENSMUSG00000026923, Notch1, notch 1, [Score=312, Expect=1e-89]; ENSMUSG00000027878, Notch2, notch 2, [Score=300, Expect=9e-86]} {Dmel: FBgn0259685, crb, crumbs, [Score=291, Expect=1e-82]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=234, Expect=5e-64]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=236, Expect=9e-65]} {RNA1509_26892} {RNA1310_37026} {RNA815_11987.1}
54. MligTC455_27609 231 4.8 Mlig455_031171

Neo: -

Age: Up-Down-Down

RYR2 1.727 - - - - 0.952 0.775 Mlig455_031171 {REF} {Length: 1840} {Human: ENSG00000198626, RYR2, ryanodine receptor 2, [Score=57.0, Expect=9e-10]; ENSG00000198838, RYR3, ryanodine receptor 3, [Score=55.8, Expect=2e-09]; ENSG00000196218, RYR1, ryanodine receptor 1, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000021313, Ryr2, ryanodine receptor 2, cardiac, [Score=57.0, Expect=6e-10]; ENSMUSG00000057378, Ryr3, ryanodine receptor 3, [Score=56.2, Expect=1e-09]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=55.1, Expect=3e-09]} {Dmel: FBgn0011286, RyR, Ryanodine receptor, [Score=52.8, Expect=1e-08]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=99.4, Expect=4e-25]} {RNA1509_17046} {RNA1310_1857} {RNA815_62.1}
55. MligTC455_43063 5711 118.98 Mlig455_008727, Mlig455_063588, Mlig455_063597

Neo: -

Age: logFC(26M/2M)=-0.428

Region-enriched R8: 1.085/0.01787

GGT1 1.725 - - - 0.769 0.956 -

Mlig455_008727 {REF} {Length: 2577} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=528.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=419, Expect=8e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [RH, Score=392, Expect=2e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=352, Expect=7e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=387, Expect=6e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=7e-148]} {RNA1509_10553, RNA1509_2471, RNA1509_29196} {RNA1310_8769, RNA1509_10553, RNA1509_29196} {RNA1509_10553, RNA1509_29196, RNA815_2837}

Mlig455_063588 {REF} {Length: 2595} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=502.5]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=409, Expect=1e-136]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=381, Expect=5e-126]} {Dmel: FBgn0025837, CG17636, [RH, Score=348, Expect=4e-113]} {Celegans: WBGene00016906, C53D5.5, [Score=357, Expect=3e-116]} {Smed: dd_Smed_v6_4591_0_2, dd_Smed_v6_4591_0_2, [RH, Score=402, Expect=5e-134]} {RNA1509_2471} {RNA1310_8769} {RNA815_2837}

Mlig455_063597 {REF} {Length: 2607} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=527.1]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=417, Expect=4e-139]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [Score=389, Expect=3e-128]} {Dmel: FBgn0025837, CG17636, [RH, Score=351, Expect=2e-113]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=386, Expect=3e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=443, Expect=4e-149]} {RNA1509_2471, RNA1509_44409} {RNA1310_8769, RNA1509_44409} {RNA1509_44409, RNA815_2837}
56. MligTC455_32112 1724 35.92 Mlig455_067479, Mlig455_067487

Neo: -

Age: -

SYT14 1.723 - - 0.762 - 0.961 -

Mlig455_067479 {REF} {Length: 2410} {Pfam: C2 domain [PF00168.32, score=47.3]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [Score=128, Expect=5e-31]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=130, Expect=3e-31]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [Score=114, Expect=2e-26]} {Smed: dd_Smed_v6_9164_0_3, dd_Smed_v6_9164_0_3, [Score=80.1, Expect=8e-16]} {RNA1509_11231} {RNA1310_10515.1} {RNA815_5645}

Mlig455_067487 {REF} {Length: 2567} {Pfam: C2 domain [PF00168.32, score=65.1]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [RH, Score=231, Expect=2e-67]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [RH, Score=229, Expect=2e-64]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [RH, Score=219, Expect=6e-62]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=73.9, Expect=1e-13]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [RH, Score=178, Expect=2e-49]} {RNA1509_11231} {RNA1310_10515.1} {RNA815_5645}
57. MligTC455_34564 216 4.51 Mlig455_045027

Neo: -

Age: -

VASH1 1.713 - - 0.735 - 0.978 - Mlig455_045027 {REF} {Length: 1457} {Pfam: Vasohibin [PF14822.8, score=320.1]} {Human: ENSG00000071246, VASH1, vasohibin 1, [RH, Score=258, Expect=2e-83]; ENSG00000143494, VASH2, vasohibin 2, [RH, Score=256, Expect=7e-83]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=261, Expect=7e-85]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=254, Expect=2e-82]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=233, Expect=4e-75]} {RNA1509_59274} {RNA1310_23626.1} {RNA815_21188.1}
58. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

CFAP20 1.713 - - - 0.743 0.970 - Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
59. MligTC455_46559 1484 30.91 Mlig455_056465

Neo: -

Age: logFC(26M/2M)=-0.295

TANC1 1.708 - - 0.747 - 0.961 - Mlig455_056465 {REF} {Length: 2067} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=50.7]; Ankyrin repeats (3 copies) [PF12796.9, score=48.4]; Ankyrin repeat [PF13606.8, score=41.8]; Ankyrin repeats (many copies) [PF13637.8, score=41.1]; Ankyrin repeat [PF00023.32, score=36.6]} {Human: ENSG00000115183, TANC1, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1, [Score=57.0, Expect=5e-08]; ENSG00000145362, ANK2, ankyrin 2, [Score=57.0, Expect=5e-08]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=55.8, Expect=9e-08]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=58.2, Expect=1e-08]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [Score=53.1, Expect=1e-07]} {RNA1509_19702, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1310_14830, RNA1509_36019, RNA1509_36843, RNA1509_6963} {RNA1509_36019, RNA1509_36843, RNA1509_6963, RNA815_5101}
60. MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

GRIK1 1.706 - - 0.756 - 0.950 -

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
61. MligTC455_48507 330 6.88 Mlig455_030151

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.466

TMEM232 1.699 - 0.743 - - 0.956 - Mlig455_030151 {REF} {Length: 2337} {TRANSSPLICED} {Pfam: Transmembrane protein family 232 [PF15877.7, score=221.6]} {Human: ENSG00000186952, TMEM232, transmembrane protein 232, [Score=155, Expect=2e-39]} {Mouse: ENSMUSG00000045036, Tmem232, transmembrane protein 232, [Score=164, Expect=2e-42]} {Smed: dd_Smed_v6_15138_0_1, dd_Smed_v6_15138_0_1, [RH, Score=160, Expect=8e-42]} {RNA1509_11088} {RNA1310_8942.1} {RNA815_6522}
62. MligTC455_23002 1386 28.88 Mlig455_066079, Mlig455_066121

Neo: -

Age: Down-Down-Up

ANKRD50 1.694 - - - - 0.956 0.738

Mlig455_066079 {REF} {Length: 4539} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=152.7]; Ankyrin repeats (many copies) [PF13637.8, score=140.9]; Ankyrin repeat [PF13606.8, score=112.2]; Ankyrin repeat [PF00023.32, score=105.1]; Ankyrin repeats (many copies) [PF13857.8, score=100.0]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=134, Expect=8e-34]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=131, Expect=4e-33]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=114, Expect=3e-27]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=117, Expect=1e-28]} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA1509_5303} {RNA1310_6276, RNA1509_33878, RNA1509_47884, RNA1509_50045} {RNA1509_33878, RNA1509_47884, RNA1509_50045, RNA815_1153}

Mlig455_066121 {REF} {Length: 4098} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=236.7]; Ankyrin repeats (many copies) [PF13637.8, score=202.9]; Protein kinase domain [PF00069.27, score=191.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.2]; Ankyrin repeat [PF13606.8, score=159.1]; Ankyrin repeat [PF00023.32, score=144.3]; Ankyrin repeats (many copies) [PF13857.8, score=135.5]; ABC1 atypical kinase-like domain [PF03109.18, score=32.5]; Fungal protein kinase [PF17667.3, score=31.9]; Kinase-like [PF14531.8, score=28.5]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=203, Expect=4e-53]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=201, Expect=1e-52]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=158, Expect=3e-39]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=157, Expect=5e-39]} {Smed: dd_Smed_v6_11663_0_4, dd_Smed_v6_11663_0_4, [Score=198, Expect=2e-53]} {RNA1509_5303} {RNA1310_6276} {RNA815_1153}
63. MligTC455_19939 22 0.45 Mlig455_011563

Neo: -

Age: -

1.693 - - - - 0.961 0.732 Mlig455_011563 {REF} {Length: 867} {NoTransDecoderORF} {RNA1310_143071} {RNA815_42689}
64. MligTC455_47575 203 4.23 Mlig455_068827

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.457

MAN1C1 1.69 - - 0.739 - 0.951 - Mlig455_068827 {REF} {Length: 3468} {Pfam: Glycosyl hydrolase family 47 [PF01532.22, score=378.5]} {Human: ENSG00000117643, MAN1C1, mannosidase alpha class 1C member 1, [Score=268, Expect=7e-82]; ENSG00000198162, MAN1A2, mannosidase alpha class 1A member 2, [Score=268, Expect=2e-81]} {Mouse: ENSMUSG00000037306, Man1c1, mannosidase, alpha, class 1C, member 1, [Score=267, Expect=2e-81]; ENSMUSG00000008763, Man1a2, mannosidase, alpha, class 1A, member 2, [Score=267, Expect=2e-81]; ENSMUSG00000003746, Man1a, mannosidase 1, alpha, [Score=264, Expect=6e-80]} {Dmel: FBgn0259170, alpha-Man-Ia, alpha-Mannosidase class I a, [Score=268, Expect=1e-81]} {Celegans: WBGene00008258, mans-2, Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5, [Score=250, Expect=1e-75]} {Smed: dd_Smed_v6_6801_0_1, dd_Smed_v6_6801_0_1, [Score=267, Expect=3e-82]} {RNA1509_48511, RNA1509_9530} {RNA1310_9474.1, RNA1509_48511, RNA1509_9530} {RNA1509_48511, RNA1509_9530, RNA815_6962}
65. MligTC455_40158 660 13.75 Mlig455_011040

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.454

Region-enriched R2: 1.509/0.04515

ZMYND12 1.689 - - 0.730 - 0.959 - Mlig455_011040 {REF} {Length: 2385} {Pfam: MYND finger [PF01753.20, score=36.1]; MalT-like TPR region [PF17874.3, score=22.6]; Tetratricopeptide repeat [PF07719.19, score=22.5]; Tetratricopeptide repeat [PF00515.30, score=21.0]; Tetratricopeptide repeat [PF13424.8, score=21.0]} {Human: ENSG00000066185, ZMYND12, zinc finger MYND-type containing 12, [RH, Score=286, Expect=1e-93]} {Mouse: ENSMUSG00000070806, Zmynd12, zinc finger, MYND domain containing 12, [RH, Score=297, Expect=4e-98]} {Smed: dd_Smed_v6_10079_0_1, dd_Smed_v6_10079_0_1, [RH, Score=393, Expect=4e-136]} {RNA1509_3913, RNA1509_42555} {RNA1310_12452, RNA1509_3913, RNA1509_42555} {RNA1509_3913, RNA1509_42555, RNA815_3855}
66. MligTC455_54077 937 19.53 Mlig455_032159, Mlig455_032165

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.640

TLL2 1.683 - - - - 0.960 0.723

Mlig455_032159 {REF} {Length: 1358} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}

Mlig455_032165 {REF} {Length: 1696} {Pfam: CUB domain [PF00431.22, score=63.7]} {Human: ENSG00000095587, TLL2, tolloid like 2, [Score=62.8, Expect=4e-10]; ENSG00000107611, CUBN, cubilin, [Score=62.0, Expect=1e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=61.2, Expect=1e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=68.9, Expect=4e-12]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}
67. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

0.98 - - - - 0.980 - Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
68. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

MX2 0.979 - - - - 0.979 - Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
69. MligTC455_26986 157 3.28 Mlig455_058044

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.496

0.975 - - - - 0.975 - Mlig455_058044 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=51.3]; Ceramide kinase C-terminal domain [PF19280.1, score=22.6]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=55.1, Expect=2e-07]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=52.4, Expect=1e-06]} {RNA1509_33630, RNA1509_39108} {RNA1310_4577, RNA1509_33630, RNA1509_39108} {RNA1509_33630, RNA1509_39108, RNA815_1173}
70. MligTC455_38072 222 4.62 Mlig455_012098, Mlig455_023289, Mlig455_023290, Mlig455_030139

Neo: -

Age: -

0.971 - - - - 0.971 -

Mlig455_012098 {REF} {Length: 3878} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_023289 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_57501} {RNA1310_60087} {RNA815_63886}

Mlig455_023290 {REF} {Length: 660} {RNA1509_44389} {RNA1310_27455} {RNA815_10592}

Mlig455_030139 {REF} {Length: 465} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
71. MligTC455_46851 507 10.56 Mlig455_059440

Neo: -

Age: logFC(26M/2M)=-0.309

0.971 - - - - 0.971 - Mlig455_059440 {REF} {Length: 3521} {TRANSSPLICED} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=85.5, Expect=2e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=72.8, Expect=7e-13]} {RNA1509_28804, RNA1509_7522} {RNA1310_3662, RNA1509_28804} {RNA1509_28804, RNA815_5689}
72. MligTC455_43627 1683 35.07 Mlig455_012966

Neo: -

Age: -

0.97 - - - - 0.970 - Mlig455_012966 {REF} {Length: 4640} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=231.1]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=2e-13]} {RNA1509_10570} {RNA1310_7155.1} {RNA815_1910.1}
73. MligTC455_31890 210 4.38 Mlig455_070942

Neo: -

Age: logFC(26M/2M)=-0.564

0.966 - - - - 0.966 - Mlig455_070942 {REF} {Length: 2335} {Pfam: MULE transposase domain [PF10551.11, score=21.4]; Domain of unknown function (DUF4806) [PF16064.7, score=19.0]} {Smed: dd_Smed_v6_24877_0_1, dd_Smed_v6_24877_0_1, [Score=52.0, Expect=2e-08]} {RNA1509_28268} {RNA1310_1293.1} {RNA815_1077}
74. MligTC455_48164 1129 23.52 Mlig455_020167

Neo: -

Age: logFC(26M/2M)=-0.425

0.963 - - - - 0.963 - Mlig455_020167 {REF} {Length: 1547} {RNA1509_31892} {RNA1310_30464, RNA1509_31892} {RNA1509_31892, RNA815_28823.1}
75. MligTC455_30192 1664 34.66 Mlig455_026693

Neo: -

Age: -

FOXRED2 0.962 - - - - 0.962 - Mlig455_026693 {REF} {Length: 18036} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=147.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=45.8]; HI0933-like protein [PF03486.16, score=31.1]; FAD dependent oxidoreductase [PF01266.26, score=26.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=25.0]; FAD binding domain [PF01494.21, score=22.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=22.5]; Flavin containing amine oxidoreductase [PF01593.26, score=21.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=20.1]} {Human: ENSG00000100350, FOXRED2, FAD dependent oxidoreductase domain containing 2, [RH, Score=493, Expect=4e-167]} {Mouse: ENSMUSG00000016552, Foxred2, FAD-dependent oxidoreductase domain containing 2, [RH, Score=498, Expect=3e-169]} {Celegans: WBGene00001479, fmo-4, Flavin-containing monooxygenase, [Score=53.5, Expect=4e-07]} {Smed: dd_Smed_v6_12138_0_1, dd_Smed_v6_12138_0_1, [RH, Score=474, Expect=4e-161]} {RNA1509_13675, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1310_861.1, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978, RNA815_570.1}
76. MligTC455_52074 36 0.74 Mlig455_000653

Neo: -

Age: -

0.961 - - - - 0.961 - Mlig455_000653 {REF} {Length: 2461} {NoTransDecoderORF} {RNA1310_118495}
77. MligTC455_33217 350 7.3 Mlig455_017510, Mlig455_025979, Mlig455_030680, Mlig455_060677, Mlig455_070125

Neo: -

Age: Down-Up-Down

0.959 - - - - 0.959 -

Mlig455_017510 {REF} {Length: 518} {NoTransDecoderORF} {RNA1509_35799} {RNA1310_37183} {RNA815_7155}

Mlig455_025979 {REF} {Length: 1819} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.1} {RNA815_7155}

Mlig455_030680 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_060677 {REF} {Length: 6928} {NoTransDecoderORF} {RNA1509_33795, RNA1509_44389} {RNA1310_14765.2, RNA1509_33795} {RNA1509_33795, RNA815_7155}

Mlig455_070125 {REF} {Length: 5305} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
78. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

0.958 - - - - 0.958 - Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
79. MligTC455_41182 1050 21.88 Mlig455_052867

Neo: -

Age: logFC(26M/2M)=-0.253

Region-enriched R4: 1.306/0.04107

AK5 0.958 - - - - 0.958 - Mlig455_052867 {REF} {Length: 2821} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=105.1]; AAA domain [PF13207.8, score=87.7]; AAA domain [PF13238.8, score=49.8]; AAA domain [PF13671.8, score=35.5]; IQ calmodulin-binding motif [PF00612.29, score=34.4]; AAA ATPase domain [PF13191.8, score=29.0]; AAA domain [PF13521.8, score=21.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.5]; AAA domain [PF13245.8, score=19.8]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [RH, Score=223, Expect=9e-64]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [RH, Score=222, Expect=1e-63]} {Dmel: FBgn0032083, CG9541, [RH, Score=108, Expect=2e-24]} {Celegans: WBGene00008746, F13E6.2, [Score=127, Expect=4e-30]} {Smed: dd_Smed_v6_5119_0_1, dd_Smed_v6_5119_0_1, [RH, Score=266, Expect=9e-78]} {RNA1509_8959} {RNA1310_6179.1, RNA1509_8959} {RNA1509_8959, RNA815_3037}
80. MligTC455_05144 33 0.69 Mlig455_036438

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_036438 {REF} {Length: 891} {NoTransDecoderORF} {RNA1310_36060}
81. MligTC455_27391 400 8.33 Mlig455_025302

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_025302 {REF} {Length: 5004} {RNA1509_12762} {RNA1310_3434.1} {RNA815_1693}
82. MligTC455_31889 414 8.63 Mlig455_027646, Mlig455_065376

Neo: -

Age: -

0.954 - - - - 0.954 -

Mlig455_027646 {REF} {Length: 613} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=20.2]} {RNA1509_2283} {RNA1310_1293.1} {RNA815_1077}

Mlig455_065376 {REF} {Length: 615} {TRANSSPLICED} {RNA1509_37997} {RNA1310_1293.1} {RNA815_1077}
83. MligTC455_42475 2357 49.11 Mlig455_034933

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_034933 {REF} {Length: 1948} {Smed: dd_Smed_v6_6979_0_1, dd_Smed_v6_6979_0_1, [RH, Score=49.7, Expect=2e-07]} {RNA1509_16213, RNA1509_2544} {RNA1310_12361.2, RNA1509_16213, RNA1509_2544} {RNA1509_16213, RNA1509_2544, RNA815_4094.1}
84. MligTC455_49465 2258 47.04 Mlig455_021850, Mlig455_021924

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.547

LCK 0.952 - - - - 0.952 -

Mlig455_021850 {REF} {Length: 2379} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=238.1]; Protein kinase domain [PF00069.27, score=165.7]; SH2 domain [PF00017.26, score=42.0]; SH3 domain [PF00018.30, score=34.3]; Variant SH3 domain [PF14604.8, score=30.4]; ABC1 atypical kinase-like domain [PF03109.18, score=25.9]; Variant SH3 domain [PF07653.19, score=23.2]; Kinase-like [PF14531.8, score=20.2]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=266, Expect=5e-82]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=259, Expect=3e-79]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=256, Expect=8e-78]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=255, Expect=8e-78]; ENSG00000136573, BLK, BLK proto-oncogene, Src family tyrosine kinase, [Score=253, Expect=7e-77]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=265, Expect=2e-81]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=264, Expect=3e-81]; ENSMUSG00000014453, Blk, B lymphoid kinase, [Score=257, Expect=1e-78]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=256, Expect=7e-78]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=254, Expect=2e-77]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=250, Expect=4e-76]} {Celegans: WBGene00005078, src-2, Tyrosine protein-kinase src-2, [Score=229, Expect=3e-68]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=303, Expect=1e-96]} {RNA1509_4982} {RNA1310_11135} {RNA815_2042.1}

Mlig455_021924 {REF} {Length: 2379} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=238.1]; Protein kinase domain [PF00069.27, score=165.7]; SH2 domain [PF00017.26, score=42.0]; SH3 domain [PF00018.30, score=34.3]; Variant SH3 domain [PF14604.8, score=30.4]; ABC1 atypical kinase-like domain [PF03109.18, score=25.9]; Variant SH3 domain [PF07653.19, score=23.2]; Kinase-like [PF14531.8, score=20.2]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=266, Expect=5e-82]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=259, Expect=3e-79]; ENSG00000010810, FYN, FYN proto-oncogene, Src family tyrosine kinase, [Score=256, Expect=8e-78]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=255, Expect=8e-78]; ENSG00000136573, BLK, BLK proto-oncogene, Src family tyrosine kinase, [Score=253, Expect=7e-77]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=265, Expect=2e-81]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=264, Expect=3e-81]; ENSMUSG00000014453, Blk, B lymphoid kinase, [Score=257, Expect=1e-78]; ENSMUSG00000019843, Fyn, Fyn proto-oncogene, [Score=256, Expect=7e-78]; ENSMUSG00000003283, Hck, hemopoietic cell kinase, [Score=254, Expect=2e-77]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=250, Expect=4e-76]} {Celegans: WBGene00005078, src-2, Tyrosine protein-kinase src-2, [Score=229, Expect=3e-68]} {Smed: dd_Smed_v6_3147_0_1, dd_Smed_v6_3147_0_1, [Score=303, Expect=1e-96]} {RNA1509_4982} {RNA1310_11135, RNA1509_4982} {RNA1509_4982, RNA815_2042.1}
85. MligTC455_49550 650 13.55 Mlig455_035011

Neo: -

Age: -

0.951 - - - - 0.951 - Mlig455_035011 {REF} {Length: 1151} {RNA1509_15666, RNA1509_28504} {RNA1310_5704, RNA1509_28504} {RNA1509_28504, RNA815_33238}
86. MligTC455_19551 361 7.52 Mlig455_047808, Mlig455_047885

Neo: -

Age: -

0.95 - - - 0.950 - -

Mlig455_047808 {REF} {Length: 3001} {Smed: dd_Smed_v6_14814_0_1, dd_Smed_v6_14814_0_1, [Score=88.2, Expect=2e-22]} {RNA1509_46635} {RNA1310_30981} {RNA815_12742}

Mlig455_047885 {REF} {Length: 1622} {Smed: dd_Smed_v6_14814_0_1, dd_Smed_v6_14814_0_1, [Score=88.2, Expect=2e-22]} {RNA1509_40551} {RNA1310_30981} {RNA815_12742}
87. MligTC455_40157 601 12.52 Mlig455_011008

Neo: -

Age: -

ZMYND12 0.95 - - - - 0.950 - Mlig455_011008 {REF} {Length: 2345} {Pfam: MYND finger [PF01753.20, score=36.1]; MalT-like TPR region [PF17874.3, score=22.6]; Tetratricopeptide repeat [PF07719.19, score=22.5]; Tetratricopeptide repeat [PF00515.30, score=21.0]; Tetratricopeptide repeat [PF13424.8, score=21.0]} {Human: ENSG00000066185, ZMYND12, zinc finger MYND-type containing 12, [RH, Score=286, Expect=1e-93]} {Mouse: ENSMUSG00000070806, Zmynd12, zinc finger, MYND domain containing 12, [RH, Score=297, Expect=4e-98]} {Smed: dd_Smed_v6_10079_0_1, dd_Smed_v6_10079_0_1, [RH, Score=393, Expect=4e-136]} {RNA1509_3913} {RNA1310_12452} {RNA815_3855}
88. MligTC455_49142 139 2.9 Mlig455_021656

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_021656 {REF} {Length: 2413} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=49.6]} {Smed: dd_Smed_v6_13233_0_1, dd_Smed_v6_13233_0_1, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1}

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