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Results for MligTC455_49015

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49015 2886 60.13 Mlig455_019168

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.204

PPP1R32 Mlig455_019168 {REF} {Length: 1846} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 32 [PF15691.7, score=381.2]} {Human: ENSG00000162148, PPP1R32, protein phosphatase 1 regulatory subunit 32, [RH, Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000035179, Ppp1r32, protein phosphatase 1, regulatory subunit 32, [RH, Score=150, Expect=2e-40]} {Smed: dd_Smed_v6_6404_0_1, dd_Smed_v6_6404_0_1, [RH, Score=263, Expect=2e-83]} {RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1310_15371.1, RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1509_2656, RNA1509_42026, RNA1509_47496, RNA815_5915}

Cumulative graph for MligTC455_49015

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.222 6.016 0.05899 0.55933
RegionR2 0.918 6.016 0.00075 0.01788
RegionR3 0.355 6.016 0.12520 0.60944
RegionR4 -0.086 6.016 0.75926 1.00000
RegionR5 -0.238 6.016 0.30713 0.64463
RegionR6 0.315 6.016 0.18655 0.75276
RegionR7 0.355 6.016 0.21309 0.82912
RegionR8 -0.397 6.016 0.31090 0.94331

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.156 6.016 0.86244 1.00000
RegenerationR2 0.477 6.016 0.04005 0.33097
RegenerationR3 0.361 6.016 0.16694 0.60142
RegenerationR4 0.522 6.016 0.05459 0.37584
RegenerationR5 0.265 6.016 0.30511 0.73234
RegenerationR6 -0.062 6.016 0.81780 0.98593
RegenerationBL 0.354 6.016 0.20654 0.54876
RegenerationTP -0.154 6.016 0.64908 0.98840


Genes with expression patterns similar to MligTC455_49015

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49015 2886 60.13 Mlig455_019168

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.204

PPP1R32 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_019168 {REF} {Length: 1846} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 32 [PF15691.7, score=381.2]} {Human: ENSG00000162148, PPP1R32, protein phosphatase 1 regulatory subunit 32, [RH, Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000035179, Ppp1r32, protein phosphatase 1, regulatory subunit 32, [RH, Score=150, Expect=2e-40]} {Smed: dd_Smed_v6_6404_0_1, dd_Smed_v6_6404_0_1, [RH, Score=263, Expect=2e-83]} {RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1310_15371.1, RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1509_2656, RNA1509_42026, RNA1509_47496, RNA815_5915}
2. MligTC455_48506 710 14.8 Mlig455_030058

Neo: -

Age: Down-Up-Down

TMEM232 4.651 0.744 0.755 0.704 0.744 0.964 0.740 Mlig455_030058 {REF} {Length: 2808} {TRANSSPLICED} {Pfam: Transmembrane protein family 232 [PF15877.7, score=258.6]} {Human: ENSG00000186952, TMEM232, transmembrane protein 232, [RH, Score=171, Expect=2e-44]} {Mouse: ENSMUSG00000045036, Tmem232, transmembrane protein 232, [RH, Score=181, Expect=6e-48]} {Smed: dd_Smed_v6_15138_0_1, dd_Smed_v6_15138_0_1, [RH, Score=163, Expect=1e-42]} {RNA1509_11088} {RNA1310_8942.1, RNA1509_11088} {RNA1509_11088, RNA815_6522}
3. MligTC455_43476 4089 85.19 Mlig455_041367

Neo: -

Age: logFC(26M/2M)=-0.284

TNNC1 4.483 - 0.862 0.871 0.888 0.887 0.975 Mlig455_041367 {REF} {Length: 1848} {Pfam: EF-hand domain pair [PF13499.8, score=49.6]; EF hand [PF00036.34, score=48.0]; EF-hand domain [PF13405.8, score=41.5]; EF hand [PF13202.8, score=41.4]; EF-hand domain pair [PF13833.8, score=29.7]} {Human: ENSG00000114854, TNNC1, troponin C1, slow skeletal and cardiac type, [Score=50.4, Expect=7e-07]; ENSG00000143933, CALM2, calmodulin 2, [Score=49.3, Expect=2e-06]; ENSG00000198668, CALM1, calmodulin 1, [Score=48.9, Expect=2e-06]; ENSG00000160014, CALM3, calmodulin 3, [Score=48.9, Expect=2e-06]} {Mouse: ENSMUSG00000027422, Rrbp1, ribosome binding protein 1, [Score=55.5, Expect=1e-07]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=54.7, Expect=2e-08]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=47.8, Expect=9e-07]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=48.1, Expect=1e-06]} {RNA1509_2843, RNA1509_31377, RNA1509_7835} {RNA1310_12201, RNA1509_2843, RNA1509_31377, RNA1509_7835} {RNA1509_2843, RNA1509_31377, RNA1509_7835, RNA815_6659.1}
4. MligTC455_47923 9994 208.21 Mlig455_031159, Mlig455_031167

Neo: -

Age: logFC(26M/2M)=-0.423

CCDC63 4.47 0.868 0.798 - 0.862 0.962 0.980

Mlig455_031159 {REF} {Length: 2325} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=22.9]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [Score=181, Expect=9e-50]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [Score=163, Expect=3e-43]; ENSMUSG00000040189, Ccdc114, coiled-coil domain containing 114, [Score=158, Expect=3e-41]} {Dmel: FBgn0038452, CG14905, [Score=159, Expect=9e-43]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [Score=431, Expect=8e-146]} {RNA1509_2578, RNA1509_9264} {RNA1310_10129.1, RNA1509_2578, RNA1509_9264} {RNA1509_2578, RNA1509_9264, RNA815_3341.1}

Mlig455_031167 {REF} {Length: 2293} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=22.9]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [Score=181, Expect=9e-50]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [Score=163, Expect=3e-43]; ENSMUSG00000040189, Ccdc114, coiled-coil domain containing 114, [Score=158, Expect=3e-41]} {Dmel: FBgn0038452, CG14905, [Score=159, Expect=9e-43]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [Score=431, Expect=8e-146]} {RNA1509_1172, RNA1509_13163, RNA1509_16375, RNA1509_2578} {RNA1310_10129.1, RNA1509_1172, RNA1509_13163, RNA1509_16375} {RNA1509_1172, RNA1509_13163, RNA1509_16375, RNA815_3341.1}
5. MligTC455_40024 3395 70.74 Mlig455_058212

Neo: -

Age: logFC(26M/2M)=-0.531

ODF3 4.228 - 0.846 0.800 0.958 0.879 0.745 Mlig455_058212 {REF} {Length: 1436} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=65.8]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=179, Expect=2e-55]; ENSG00000177989, ODF3B, outer dense fiber of sperm tails 3B, [RH, Score=174, Expect=3e-53]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [Score=172, Expect=1e-52]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=3e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=322, Expect=3e-112]} {RNA1509_14103, RNA1509_4352} {RNA1310_23191, RNA1509_14103, RNA1509_4352} {RNA1509_14103, RNA1509_4352, RNA815_9849}
6. MligTC455_43616 1798 37.45 Mlig455_024513

Neo: -

Age: logFC(26M/2M)=-0.338

Region-enriched R2: 1.066/0.02738

CFAP57 4.163 - 0.839 0.770 0.814 0.961 0.779 Mlig455_024513 {REF} {Length: 5805} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=65.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=24.0]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=20.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=496, Expect=5e-155]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1620, Expect=0.0]} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA1509_836} {RNA1310_1737, RNA1509_14259, RNA1509_18569, RNA1509_42897} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA815_558}
7. MligTC455_15346 10495 218.65 Mlig455_014073, Mlig455_014091

Neo: -

Age: -

TEKT4 4.138 - 0.748 0.723 0.860 0.970 0.837

Mlig455_014073 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=471.5]; Intermediate filament protein [PF00038.23, score=20.4]} {Human: ENSG00000163060, TEKT4, tektin 4, [RH, Score=404, Expect=3e-138]} {Mouse: ENSMUSG00000024175, Tekt4, tektin 4, [RH, Score=419, Expect=2e-144]} {Dmel: FBgn0028902, Tektin-A, Tektin A, [RH, Score=219, Expect=3e-65]} {Smed: dd_Smed_v6_4872_0_1, dd_Smed_v6_4872_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_689} {RNA1310_17094.1} {RNA815_4941}

Mlig455_014091 {REF} {Length: 1995} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=471.5]; Intermediate filament protein [PF00038.23, score=20.4]} {Human: ENSG00000163060, TEKT4, tektin 4, [RH, Score=404, Expect=3e-138]} {Mouse: ENSMUSG00000024175, Tekt4, tektin 4, [RH, Score=419, Expect=2e-144]} {Dmel: FBgn0028902, Tektin-A, Tektin A, [RH, Score=219, Expect=3e-65]} {Smed: dd_Smed_v6_4872_0_1, dd_Smed_v6_4872_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416} {RNA1310_17094.1, RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416} {RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416, RNA815_4941}
8. MligTC455_39504 298 6.2 Mlig455_017354

Neo: -

Age: -

Region-enriched R2: 2.428/0.04005

DTHD1 4.12 0.805 - 0.704 0.886 0.774 0.951 Mlig455_017354 {REF} {Length: 3800} {Pfam: Death domain [PF00531.24, score=30.4]} {Human: ENSG00000197057, DTHD1, death domain containing 1, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000090326, Dthd1, death domain containing 1, [RH, Score=105, Expect=8e-23]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [RH, Score=169, Expect=3e-43]} {RNA1509_9917} {RNA1310_4320.1} {RNA815_4192.1}
9. MligTC455_41182 1050 21.88 Mlig455_052867

Neo: -

Age: logFC(26M/2M)=-0.253

Region-enriched R4: 1.306/0.04107

AK5 4.105 - 0.760 0.739 0.814 0.953 0.839 Mlig455_052867 {REF} {Length: 2821} {TRANSSPLICED} {Pfam: Adenylate kinase [PF00406.24, score=105.1]; AAA domain [PF13207.8, score=87.7]; AAA domain [PF13238.8, score=49.8]; AAA domain [PF13671.8, score=35.5]; IQ calmodulin-binding motif [PF00612.29, score=34.4]; AAA ATPase domain [PF13191.8, score=29.0]; AAA domain [PF13521.8, score=21.9]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=20.5]; AAA domain [PF13245.8, score=19.8]} {Human: ENSG00000154027, AK5, adenylate kinase 5, [RH, Score=223, Expect=9e-64]} {Mouse: ENSMUSG00000039058, Ak5, adenylate kinase 5, [RH, Score=222, Expect=1e-63]} {Dmel: FBgn0032083, CG9541, [RH, Score=108, Expect=2e-24]} {Celegans: WBGene00008746, F13E6.2, [Score=127, Expect=4e-30]} {Smed: dd_Smed_v6_5119_0_1, dd_Smed_v6_5119_0_1, [RH, Score=266, Expect=9e-78]} {RNA1509_8959} {RNA1310_6179.1, RNA1509_8959} {RNA1509_8959, RNA815_3037}
10. MligTC455_38233 10194 212.37 Mlig455_053363

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.248

Region-specific R2: 1.769

Region-enriched R4: 1.123/0.00792

4.039 - 0.724 0.728 0.772 0.865 0.950 Mlig455_053363 {REF} {Length: 1744} {Pfam: Dynein light chain type 1 [PF01221.20, score=48.7]; EF hand [PF00036.34, score=37.0]; EF-hand domain pair [PF13499.8, score=32.7]; EF-hand domain [PF13405.8, score=25.8]; EF-hand domain pair [PF13833.8, score=20.8]} {Smed: dd_Smed_v6_6707_0_3, dd_Smed_v6_6707_0_3, [Score=121, Expect=2e-35]} {RNA1509_1914, RNA1509_30676, RNA1509_56161} {RNA1310_34597.1, RNA1509_1914, RNA1509_30676, RNA1509_56161} {RNA1509_1914, RNA1509_30676, RNA1509_56161, RNA815_16070}
11. MligTC455_44301 1697 35.36 Mlig455_000545

Neo: -

Age: -

3.547 - 0.843 - 0.978 0.833 0.893 Mlig455_000545 {REF} {Length: 1706} {TRANSSPLICED} {Smed: dd_Smed_v6_6108_0_1, dd_Smed_v6_6108_0_1, [RH, Score=190, Expect=9e-63]} {RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1310_30744, RNA1509_16536, RNA1509_27118, RNA1509_9934} {RNA1509_16536, RNA1509_27118, RNA1509_9934, RNA815_13864}
12. MligTC455_29450 827 17.23 Mlig455_026424

Neo: -

Age: logFC(26M/2M)=-0.523

LMNTD1 3.545 - - 0.803 0.871 0.956 0.915 Mlig455_026424 {REF} {Length: 3702} {Pfam: Intermediate filament protein [PF00038.23, score=52.8]; Lamin Tail Domain [PF00932.21, score=40.5]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=142, Expect=7e-36]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.8, Expect=9e-13]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.4, Expect=9e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=228, Expect=1e-62]} {RNA1509_16713, RNA1509_7063} {RNA1310_3989.1, RNA1509_16713, RNA1509_7063} {RNA1509_16713, RNA1509_7063, RNA815_1147.1}
13. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

LMNTD1 3.543 - - 0.802 0.876 0.954 0.911 Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
14. MligTC455_27220 3965 82.6 Mlig455_007059

Neo: -

Age: logFC(26M/2M)=-0.158

TEKT2 3.458 - 0.847 - 0.844 0.811 0.956 Mlig455_007059 {REF} {Length: 2591} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=425.6]} {Human: ENSG00000092850, TEKT2, tektin 2, [RH, Score=421, Expect=5e-145]} {Mouse: ENSMUSG00000028845, Tekt2, tektin 2, [RH, Score=387, Expect=4e-132]} {Dmel: FBgn0034816, CG3085, [RH, Score=213, Expect=2e-64]} {Celegans: WBGene00019828, R02E12.4, [Score=78.2, Expect=2e-15]} {Smed: dd_Smed_v6_2339_0_1, dd_Smed_v6_2339_0_1, [RH, Score=543, Expect=0.0]} {RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859} {RNA1310_13089.2, RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859} {RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859, RNA815_4479}
15. MligTC455_13905 34 0.71 Mlig455_023395

Neo: -

Age: -

3.43 - - 0.772 0.887 0.815 0.956 Mlig455_023395 {REF} {Length: 1110} {Smed: dd_Smed_v6_12856_0_1, dd_Smed_v6_12856_0_1, [Score=47.0, Expect=2e-06]} {RNA1509_18233} {RNA1310_51675} {RNA815_25040}
16. MligTC455_41055 112 2.34 Mlig455_044574

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.659

Region-enriched R2: 6.247/0.00008

3.333 - 0.742 0.738 0.900 - 0.953 Mlig455_044574 {REF} {Length: 1203} {Smed: dd_Smed_v6_9736_0_1, dd_Smed_v6_9736_0_1, [Score=86.7, Expect=1e-20]} {RNA1509_58567} {RNA1310_87689} {RNA815_53353}
17. MligTC455_16285 2682 55.88 Mlig455_020319

Neo: -

Age: Down-Up-Up

TMEM107 3.332 - 0.815 0.739 - 0.966 0.812 Mlig455_020319 {REF} {Length: 920} {Pfam: Transmembrane protein [PF14995.8, score=118.5]} {Human: ENSG00000179029, TMEM107, transmembrane protein 107, [RH, Score=127, Expect=1e-37]} {Mouse: ENSMUSG00000020895, Tmem107, transmembrane protein 107, [RH, Score=123, Expect=2e-36]} {Smed: dd_Smed_v6_13204_0_4, dd_Smed_v6_13204_0_4, [RH, Score=97.4, Expect=2e-26]} {RNA1509_30443} {RNA1310_40623} {RNA815_15713}
18. MligTC455_19030 628 13.08 Mlig455_046052

Neo: -

Age: -

Region-enriched R2: 3.353/0.00000

ADGRL3 3.332 - 0.830 - 0.753 0.795 0.954 Mlig455_046052 {REF} {Length: 7405} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=104.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=61.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=54.3]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=28.0]} {Human: ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [Score=157, Expect=8e-38]} {Mouse: ENSMUSG00000037605, Adgrl3, adhesion G protein-coupled receptor L3, [Score=158, Expect=5e-38]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=72.4, Expect=5e-12]} {Celegans: WBGene00002251, lat-1, Latrophilin-like protein 1, [Score=107, Expect=5e-23]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=587, Expect=1e-173]} {RNA1509_17130, RNA1509_4023, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1310_254.2, RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867, RNA815_85.1}
19. MligTC455_46341 243 5.06 Mlig455_052880, Mlig455_052884

Neo: -

Age: -

3.259 0.739 - - 0.723 0.836 0.961

Mlig455_052880 {REF} {Length: 1228} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=28.6]; Dpy-30 motif [PF05186.15, score=22.0]; Ankyrin repeats (many copies) [PF13637.8, score=20.9]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=60.5, Expect=6e-10]} {RNA1509_39973} {RNA1310_21889} {RNA815_13094}

Mlig455_052884 {REF} {Length: 1926} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=39.4]; Ankyrin repeats (many copies) [PF13637.8, score=27.7]; Ankyrin repeats (many copies) [PF13857.8, score=24.6]; Dpy-30 motif [PF05186.15, score=21.6]} {Smed: dd_Smed_v6_29956_0_1, dd_Smed_v6_29956_0_1, [Score=72.8, Expect=1e-13]} {RNA1509_39973} {RNA1310_21889, RNA1509_39973} {RNA1509_39973, RNA815_13094}
20. MligTC455_47393 241 5.03 Mlig455_008718, Mlig455_063579

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.683/0.00849

CALM2 3.216 0.759 - - 0.711 0.788 0.958

Mlig455_008718 {REF} {Length: 1727} {Pfam: EF hand [PF00036.34, score=99.3]; EF-hand domain pair [PF13499.8, score=95.1]; EF-hand domain [PF13405.8, score=86.1]; EF-hand domain pair [PF13833.8, score=76.8]; EF hand [PF13202.8, score=75.3]; EF-hand domain [PF14658.8, score=46.0]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=27.9]; EF-hand domain [PF08976.13, score=23.4]; Uncharacterised protein family (UPF0154) [PF03672.15, score=18.7]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=108, Expect=4e-30]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=4e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=4e-30]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-30]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=108, Expect=2e-30]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=1e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-30]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-30]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=114, Expect=8e-33]} {RNA1310_33847.1} {RNA815_17211}

Mlig455_063579 {REF} {Length: 2562} {Pfam: EF hand [PF00036.34, score=95.8]; EF-hand domain pair [PF13499.8, score=92.8]; EF-hand domain [PF13405.8, score=82.9]; EF-hand domain pair [PF13833.8, score=74.4]; EF hand [PF13202.8, score=72.2]; EF-hand domain [PF14658.8, score=43.8]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=38.5]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.6]; EF-hand domain [PF08976.13, score=21.4]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=111, Expect=7e-30]; ENSG00000198668, CALM1, calmodulin 1, [Score=108, Expect=3e-29]; ENSG00000160014, CALM3, calmodulin 3, [Score=108, Expect=3e-29]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=111, Expect=7e-30]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=108, Expect=2e-29]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=108, Expect=2e-29]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=106, Expect=9e-29]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=107, Expect=3e-29]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=107, Expect=2e-29]} {Smed: dd_Smed_v6_3441_0_1, dd_Smed_v6_3441_0_1, [Score=111, Expect=9e-31]} {RNA1310_12431.1} {RNA815_17211}
21. MligTC455_40555 4294 89.47 Mlig455_028405, Mlig455_028439

Neo: -

Age: logFC(26M/2M)=0.704

Region-specific R2: 2.095

Region-enriched R2: 1.320/0.00861

Regeneration-depleted BL: -2.352
Regeneration-depleted R6: -2.070
Regeneration-depleted R3: -1.661

CALML3 3.201 - - 0.736 0.964 0.780 0.721

Mlig455_028405 {REF} {Length: 1039} {Pfam: EF-hand domain pair [PF13499.8, score=107.0]; EF-hand domain [PF13405.8, score=88.7]; EF hand [PF00036.34, score=85.4]; EF-hand domain pair [PF13833.8, score=63.1]; EF hand [PF13202.8, score=46.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.9]; EF-hand domain [PF14658.8, score=27.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.9]; Ca2+ insensitive EF hand [PF08726.12, score=22.1]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=1e-24]; ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=94.7, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=93.2, Expect=2e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=93.2, Expect=2e-24]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=90.5, Expect=2e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=89.7, Expect=2e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=89.7, Expect=2e-23]} {RNA1509_7376} {RNA1310_30171} {RNA815_22911}

Mlig455_028439 {REF} {Length: 1042} {Pfam: EF-hand domain pair [PF13499.8, score=107.0]; EF-hand domain [PF13405.8, score=88.7]; EF hand [PF00036.34, score=85.4]; EF-hand domain pair [PF13833.8, score=63.1]; EF hand [PF13202.8, score=46.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.9]; EF-hand domain [PF14658.8, score=27.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.9]; Ca2+ insensitive EF hand [PF08726.12, score=22.1]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=1e-24]; ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=94.7, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=93.2, Expect=2e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=93.2, Expect=2e-24]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=90.5, Expect=2e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=89.7, Expect=2e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=89.7, Expect=2e-23]} {RNA1509_7376} {RNA1310_30171, RNA1509_7376} {RNA1509_7376, RNA815_22911}
22. MligTC455_50676 3764 78.41 Mlig455_024344

Neo: -

Age: -

IQCD 3.196 - 0.819 - 0.716 0.959 0.702 Mlig455_024344 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_1833, RNA1509_46413} {RNA1310_4220.1, RNA1509_46413} {RNA1509_46413, RNA815_1223.1}
23. MligTC455_43666 172 3.59 Mlig455_051408

Neo: -

Age: logFC(26M/2M)=-0.352

KY 3.177 0.767 - - 0.953 0.750 0.707 Mlig455_051408 {REF} {Length: 5047} {Human: ENSG00000174611, KY, kyphoscoliosis peptidase, [Score=111, Expect=2e-24]} {Mouse: ENSMUSG00000035606, Ky, kyphoscoliosis peptidase, [Score=111, Expect=1e-24]} {Dmel: FBgn0050147, Hil, Hillarin, [Score=150, Expect=7e-37]} {Celegans: WBGene00003089, ltd-1, Lim and Transglutaminase Domain; Lim and transglutaminase domain protein, [Score=139, Expect=1e-34]} {Smed: dd_Smed_v6_5330_0_1, dd_Smed_v6_5330_0_1, [Score=137, Expect=1e-32]} {RNA1509_7582} {RNA1310_2203} {RNA815_6135}
24. MligTC455_40554 2265 47.18 Mlig455_028418

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.536

Region-specific R2: 2.078

Region-enriched R2: 1.385/0.00761

Regeneration-depleted BL: -2.309
Regeneration-depleted R6: -1.979

CALML3 3.16 - - 0.724 0.963 0.759 0.714 Mlig455_028418 {REF} {Length: 966} {Pfam: EF-hand domain pair [PF13499.8, score=107.0]; EF-hand domain [PF13405.8, score=88.7]; EF hand [PF00036.34, score=85.4]; EF-hand domain pair [PF13833.8, score=63.1]; EF hand [PF13202.8, score=46.5]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=27.9]; EF-hand domain [PF14658.8, score=27.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=25.9]; Ca2+ insensitive EF hand [PF08726.12, score=22.1]} {Human: ENSG00000178363, CALML3, calmodulin like 3, [Score=94.0, Expect=1e-24]; ENSG00000143933, CALM2, calmodulin 2, [Score=93.2, Expect=3e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=93.2, Expect=3e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=93.2, Expect=3e-24]} {Mouse: ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=94.7, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=93.2, Expect=2e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=93.2, Expect=2e-24]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=93.2, Expect=2e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=90.5, Expect=2e-23]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=89.7, Expect=2e-23]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=89.7, Expect=2e-23]} {RNA1509_2799, RNA1509_7376} {RNA1310_30171, RNA1509_2799} {RNA1509_2799, RNA815_22911}
25. MligTC455_44176 89 1.85 Mlig455_022911

Neo: -

Age: -

TNKS 2.768 - - - 0.925 0.891 0.952 Mlig455_022911 {REF} {Length: 1883} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=67.0]; Ankyrin repeats (3 copies) [PF12796.9, score=64.6]; Ankyrin repeats (many copies) [PF13857.8, score=59.2]; Ankyrin repeat [PF13606.8, score=50.9]; Ankyrin repeat [PF00023.32, score=50.1]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=57.8, Expect=3e-08]; ENSG00000285372, AC270292.3, tankyrase, [Score=56.6, Expect=7e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=57.8, Expect=1e-08]; ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=57.8, Expect=1e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=57.8, Expect=2e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=57.4, Expect=1e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.8, Expect=9e-08]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=55.5, Expect=8e-08]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.5, Expect=1e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=55.5, Expect=4e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=55.1, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=55.1, Expect=8e-08]} {Dmel: FBgn0040752, Prosap, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=62.0, Expect=4e-10]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
26. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 2.736 - - - 0.951 0.836 0.949

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
27. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 2.709 - - - 0.882 0.869 0.958

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
28. MligTC455_37139 1583 32.98 Mlig455_017144, Mlig455_019681

Neo: -

Age: -

TRPM3 2.707 - - - 0.839 0.951 0.917

Mlig455_017144 {REF} {Length: 5140} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=159.9]; SLOG in TRPM, prokaryote [PF18171.3, score=53.1]; Ion transport protein [PF00520.33, score=37.8]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=358, Expect=3e-102]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=360, Expect=4e-103]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=335, Expect=1e-95]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=243, Expect=5e-65]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [RH, Score=502, Expect=2e-155]} {RNA1509_6375} {RNA1310_1012, RNA1509_6375} {RNA1509_6375, RNA815_5496.1}

Mlig455_019681 {REF} {Length: 5114} {TRANSSPLICED} {Pfam: SLOG in TRPM [PF18139.3, score=161.2]; SLOG in TRPM, prokaryote [PF18171.3, score=53.2]; Ion transport protein [PF00520.33, score=37.2]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=364, Expect=5e-103]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=363, Expect=1e-102]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=345, Expect=9e-97]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=239, Expect=1e-63]} {Smed: dd_Smed_v6_9288_0_1, dd_Smed_v6_9288_0_1, [RH, Score=508, Expect=1e-157]} {RNA1509_43040, RNA1509_6375} {RNA1310_1012, RNA1509_43040} {RNA1509_43040, RNA815_5496.1}
29. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

2.7 - - - 0.878 0.866 0.956 Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
30. MligTC455_15598 45 0.94 Mlig455_021461

Neo: -

Age: Down-Up-Up

2.677 - - - 0.965 0.846 0.866 Mlig455_021461 {REF} {Length: 2020} {RNA1310_35982.1} {RNA815_27626}
31. MligTC455_53778 951 19.82 Mlig455_007965, Mlig455_015595

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.392

Region-enriched R4: 2.645/0.00192

PRXL2C 2.676 - - - 0.839 0.958 0.879

Mlig455_007965 {REF} {Length: 1357} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=24.2]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [Score=108, Expect=6e-30]} {RNA1509_57652} {RNA1310_27001.1} {RNA815_11622}

Mlig455_015595 {REF} {Length: 1838} {Pfam: AhpC/TSA antioxidant enzyme [PF13911.8, score=40.9]} {Human: ENSG00000158122, PRXL2C, peroxiredoxin like 2C, [RH, Score=135, Expect=5e-39]} {Mouse: ENSMUSG00000021482, Aaed1, AhpC/TSA antioxidant enzyme domain containing 1, [Score=125, Expect=3e-35]} {Smed: dd_Smed_v6_4424_0_1, dd_Smed_v6_4424_0_1, [RH, Score=149, Expect=3e-45]} {RNA1509_57652} {RNA1310_27001.2, RNA1509_57652} {RNA1509_57652, RNA815_11622}
32. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

CCDC39 2.667 - - - 0.796 0.959 0.912 Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
33. MligTC455_44177 70 1.46 Mlig455_022828, Mlig455_022920

Neo: -

Age: -

TNKS 2.666 - - - 0.878 0.836 0.952

Mlig455_022828 {REF} {Length: 1654} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=58.3]; Ankyrin repeats (many copies) [PF13637.8, score=51.4]; Ankyrin repeats (many copies) [PF13857.8, score=43.5]; Ankyrin repeat [PF00023.32, score=38.9]; Ankyrin repeat [PF13606.8, score=35.6]} {Dmel: FBgn0039955, CG41099, [Score=56.6, Expect=5e-08]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.1, Expect=4e-07]} {Smed: dd_Smed_v6_11252_0_1, dd_Smed_v6_11252_0_1, [Score=50.8, Expect=1e-06]} {RNA1509_39040} {RNA1310_886.1} {RNA815_14632}

Mlig455_022920 {REF} {Length: 1424} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=65.4]; Ankyrin repeats (3 copies) [PF12796.9, score=61.1]; Ankyrin repeats (many copies) [PF13857.8, score=57.9]; Ankyrin repeat [PF13606.8, score=50.1]; Ankyrin repeat [PF00023.32, score=49.7]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=56.2, Expect=9e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000285372, AC270292.3, tankyrase, [Score=55.5, Expect=2e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=54.3, Expect=3e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=53.5, Expect=8e-07]} {Mouse: ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=56.6, Expect=3e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=56.6, Expect=3e-08]; ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=56.2, Expect=3e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=56.2, Expect=6e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.1, Expect=2e-07]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.1, Expect=2e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=54.3, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=53.9, Expect=2e-07]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=53.9, Expect=2e-07]} {Dmel: FBgn0040752, Prosap, [Score=58.5, Expect=1e-08]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=51.6, Expect=9e-07]} {Smed: dd_Smed_v6_2072_0_20, dd_Smed_v6_2072_0_20, [Score=59.3, Expect=3e-09]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
34. MligTC455_23948 292 6.08 Mlig455_036247

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.514/0.03753

CDA 2.656 - - - 0.953 0.862 0.841 Mlig455_036247 {REF} {Length: 1565} {Pfam: Cytidine and deoxycytidylate deaminase zinc-binding region [PF00383.25, score=39.2]; Cytidine and deoxycytidylate deaminase zinc-binding region [PF08211.14, score=32.7]} {Human: ENSG00000158825, CDA, cytidine deaminase, [RH, Score=99.0, Expect=1e-26]} {Mouse: ENSMUSG00000028755, Cda, cytidine deaminase, [Score=91.3, Expect=8e-24]} {Dmel: FBgn0032002, CG8353, [RH, Score=87.8, Expect=2e-22]} {Celegans: WBGene00000392, cdd-2, Cytidine deaminase, [Score=86.3, Expect=5e-22]} {Smed: dd_Smed_v6_3308_0_1, dd_Smed_v6_3308_0_1, [Score=78.6, Expect=2e-19]} {RNA1509_38090} {RNA1310_17876} {RNA815_13341.1}
35. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

ABCG2 2.625 - - - 0.884 0.961 0.780 Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
36. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 2.623 - - - 0.793 0.872 0.958 Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
37. MligTC455_34365 761 15.86 Mlig455_045898

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.155

2.621 - - 0.767 0.899 0.955 - Mlig455_045898 {REF} {Length: 1534} {RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1310_33460, RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1509_18388, RNA1509_36026, RNA1509_43852, RNA815_35266}
38. MligTC455_20722 36 0.74 Mlig455_001696, Mlig455_066078, Mlig455_066120

Neo: -

Age: -

2.614 - - - 0.958 0.753 0.903

Mlig455_001696 {REF} {Length: 1535} {RNA1310_134737} {RNA815_57224}

Mlig455_066078 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=20.4]} {RNA1310_134737} {RNA815_57224}

Mlig455_066120 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=25.9]} {RNA1310_134737} {RNA815_57224}
39. MligTC455_19279 4576 95.33 Mlig455_057411

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.654

Region-specific R2: 5.173

Region-enriched R2: 4.585/0.00000
Region-enriched R3: 2.611/0.00003

CHRNA10 2.6 - - - 0.906 0.736 0.958 Mlig455_057411 {REF} {Length: 1075} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=85.3]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=91.3, Expect=1e-20]} {Mouse: ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=92.0, Expect=7e-21]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=88.2, Expect=1e-19]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=110, Expect=2e-27]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=120, Expect=4e-31]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=96.3, Expect=8e-23]} {RNA1509_1306} {RNA1310_34970} {RNA815_15305.1}
40. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

MAPK15 2.551 - 0.774 - - 0.956 0.821

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
41. MligTC455_15692 65 1.36 Mlig455_007333

Neo: -

Age: -

2.551 - - - 0.953 0.742 0.856 Mlig455_007333 {REF} {Length: 1301} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=48.2]} {Smed: dd_Smed_v6_13661_0_2, dd_Smed_v6_13661_0_2, [Score=199, Expect=8e-63]} {RNA1509_40799} {RNA1310_41666} {RNA815_13749}
42. MligTC455_40989 801 16.68 Mlig455_016294

Neo: -

Age: logFC(26M/2M)=0.270

PKD2 2.55 - - - 0.866 0.733 0.951 Mlig455_016294 {REF} {Length: 3179} {Pfam: Polycystin cation channel [PF08016.14, score=486.5]; Ion transport protein [PF00520.33, score=90.3]; EF hand [PF00036.34, score=23.7]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=718, Expect=0.0]; ENSG00000107593, PKD2L1, polycystin 2 like 1, transient receptor potential cation channel, [RH, Score=712, Expect=0.0]} {Mouse: ENSMUSG00000037578, Pkd2l1, polycystic kidney disease 2-like 1, [RH, Score=704, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [RH, Score=310, Expect=2e-91]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [RH, Score=370, Expect=7e-116]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=743, Expect=0.0]} {RNA1509_14023, RNA1509_24240} {RNA1310_4836.1, RNA1509_14023, RNA1509_24240} {RNA1509_14023, RNA1509_24240, RNA815_4677}
43. MligTC455_49484 10996 229.08 Mlig455_045342

Neo: -

Age: logFC(26M/2M)=-0.289

Region-enriched R2: 1.032/0.00001

PCCB 2.546 - - - 0.719 0.950 0.877 Mlig455_045342 {REF} {Length: 2338} {TRANSSPLICED} {Pfam: Carboxyl transferase domain [PF01039.24, score=621.7]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=25.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [RH, Score=789, Expect=0.0]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [RH, Score=785, Expect=0.0]} {Dmel: FBgn0042083, CG3267, [Score=235, Expect=6e-70]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [RH, Score=785, Expect=0.0]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [RH, Score=839, Expect=0.0]} {RNA1509_1631, RNA1509_328} {RNA1310_10357.1, RNA1509_1631} {RNA1509_1631, RNA815_3334.1}
44. MligTC455_49485 10924 227.58 Mlig455_045426

Neo: -

Age: logFC(26M/2M)=-0.286

Region-enriched R2: 1.070/0.00000

PCCB 2.54 - - - 0.713 0.953 0.874 Mlig455_045426 {REF} {Length: 1500} {Pfam: Carboxyl transferase domain [PF01039.24, score=326.0]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=24.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [Score=393, Expect=8e-137]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [Score=393, Expect=7e-136]} {Dmel: FBgn0042083, CG3267, [Score=122, Expect=1e-31]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [Score=385, Expect=4e-133]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [Score=428, Expect=2e-149]} {RNA1509_1810} {RNA1310_10357.1} {RNA815_3334.1}
45. MligTC455_41325 202 4.2 Mlig455_025012

Neo: -

Age: Up-Down-Up

CCDC151 2.533 - - - 0.848 0.728 0.957 Mlig455_025012 {REF} {Length: 2382} {TRANSSPLICED} {Human: ENSG00000198003, CCDC151, coiled-coil domain containing 151, [Score=251, Expect=5e-75]} {Mouse: ENSMUSG00000039632, Ccdc151, coiled-coil domain containing 151, [Score=261, Expect=4e-79]} {Dmel: FBgn0036219, CCDC151, Coiled-coil domain containing protein 151, [Score=111, Expect=2e-25]} {Smed: dd_Smed_v6_4526_0_1, dd_Smed_v6_4526_0_1, [Score=463, Expect=3e-158]} {RNA1509_18758} {RNA1310_9513.1} {RNA815_24234}
46. MligTC455_54282 74 1.54 Mlig455_020191

Neo: -

Age: -

2.52 - - - 0.800 0.765 0.955 Mlig455_020191 {REF} {Length: 937} {RNA1509_48973} {RNA1310_40738.2} {RNA815_31898}
47. MligTC455_27904 110 2.29 Mlig455_028965

Neo: -

Age: -

2.506 - - - 0.959 0.796 0.751 Mlig455_028965 {REF} {Length: 8009} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=50.4, Expect=7e-06]} {RNA1509_4697} {RNA1310_228} {RNA815_3412.1}
48. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

FLNB 2.492 - - - 0.710 0.961 0.821

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
49. MligTC455_50677 3742 77.95 Mlig455_024461

Neo: -

Age: -

IQCD 2.485 - 0.808 - 0.720 0.957 - Mlig455_024461 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1310_4220.1, RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931, RNA815_1223.1}
50. MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

GRIK1 2.472 - 0.727 0.780 - 0.965 -

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
51. MligTC455_50927 254 5.29 Mlig455_070541, Mlig455_070562

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

Region-enriched R2: 7.883/0.00008
Region-enriched R3: 4.441/0.03979

FZD4 2.457 0.721 - - - 0.782 0.954

Mlig455_070541 {REF} {Length: 3522} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=471, Expect=6e-159]} {RNA1509_15834} {RNA1310_3800, RNA1509_15834} {RNA1509_15834, RNA815_19571}

Mlig455_070562 {REF} {Length: 3527} {Pfam: Frizzled/Smoothened family membrane region [PF01534.19, score=339.1]; Fz domain [PF01392.24, score=88.1]} {Human: ENSG00000174804, FZD4, frizzled class receptor 4, [RH, Score=446, Expect=1e-149]} {Mouse: ENSMUSG00000049791, Fzd4, frizzled class receptor 4, [RH, Score=446, Expect=2e-149]} {Dmel: FBgn0001085, fz, frizzled, [Score=315, Expect=3e-98]} {Celegans: WBGene00000478, cfz-2, Frizzled-2, [Score=284, Expect=5e-87]} {Smed: dd_Smed_v6_7210_0_1, dd_Smed_v6_7210_0_1, [RH, Score=470, Expect=8e-159]} {RNA1509_15834} {RNA1310_3800} {RNA815_19571}
52. MligTC455_50589 29 0.61 Mlig455_010626, Mlig455_010716

Neo: -

Age: Down-Up-Down

2.444 - - 0.734 0.757 - 0.953

Mlig455_010626 {REF} {Length: 2021} {Pfam: Tctex-1 family [PF03645.15, score=27.5]} {RNA1310_36440}

Mlig455_010716 {REF} {Length: 2038} {Pfam: Tctex-1 family [PF03645.15, score=27.2]} {RNA1310_36440}
53. MligTC455_52942 1583 32.98 Mlig455_016027

Neo: -

Age: Down-Up-Down

PNPT1 2.423 - - 0.717 0.720 0.986 - Mlig455_016027 {REF} {Length: 2518} {Pfam: Ligand-gated ion channel [PF00060.28, score=20.1]} {Human: ENSG00000138035, PNPT1, polyribonucleotide nucleotidyltransferase 1, [RH, Score=53.1, Expect=3e-07]} {Mouse: ENSMUSG00000020464, Pnpt1, polyribonucleotide nucleotidyltransferase 1, [RH, Score=54.7, Expect=5e-08]} {Smed: dd_Smed_v6_8233_0_1, dd_Smed_v6_8233_0_1, [Score=47.4, Expect=6e-06]} {RNA1509_45927} {RNA1310_3249} {RNA815_1535.1}
54. MligTC455_52943 3134 65.28 Mlig455_054948, Mlig455_054962

Neo: -

Age: -

GRIK5 2.421 - - 0.717 0.719 0.985 -

Mlig455_054948 {REF} {Length: 3322} {Pfam: Ligand-gated ion channel [PF00060.28, score=71.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=56.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=44.7]} {Human: ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=119, Expect=6e-27]} {Dmel: FBgn0038837, CG3822, [Score=127, Expect=8e-30]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=115, Expect=6e-26]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [RH, Score=107, Expect=1e-23]} {RNA1509_35543, RNA1509_3983} {RNA1310_4551, RNA1509_35543} {RNA1509_35543, RNA815_1535.1}

Mlig455_054962 {REF} {Length: 4559} {Pfam: Ligand-gated ion channel [PF00060.28, score=71.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=56.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=44.7]} {Human: ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=118, Expect=1e-26]} {Mouse: ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=119, Expect=6e-27]} {Dmel: FBgn0038837, CG3822, [Score=127, Expect=9e-30]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=115, Expect=6e-26]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [RH, Score=107, Expect=1e-23]} {RNA1509_3983} {RNA1310_4551, RNA1509_3983} {RNA1509_3983, RNA815_1535.1}
55. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

2.414 - - - 0.718 0.954 0.742 Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
56. MligTC455_29408 45 0.94 Mlig455_038322

Neo: -

Age: -

Region-enriched R2: 8.586/0.00762

MB 1.902 - - - 0.953 - 0.949 Mlig455_038322 {REF} {Length: 2059} {Pfam: Globin [PF00042.24, score=57.8]} {Human: ENSG00000198125, MB, myoglobin, [RH, Score=47.8, Expect=5e-07]} {Mouse: ENSMUSG00000018893, Mb, myoglobin, [RH, Score=45.4, Expect=2e-06]} {Celegans: WBGene00008996, glb-14, GLoBin related, [Score=51.6, Expect=4e-08]} {Smed: dd_Smed_v6_15997_0_1, dd_Smed_v6_15997_0_1, [RH, Score=63.5, Expect=1e-12]} {RNA1509_48898} {RNA1310_47695} {RNA815_7096.1}
57. MligTC455_29929 164 3.41 Mlig455_030237, Mlig455_068015

Neo: -

Age: -

Region-enriched R2: 4.901/0.00350

SIX6 1.889 - - - 0.954 - 0.935

Mlig455_030237 {REF} {Length: 2545} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.1]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=8e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=6e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=9e-93]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=2e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=2e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}

Mlig455_068015 {REF} {Length: 2713} {Pfam: Transcriptional regulator, SIX1, N-terminal SD domain [PF16878.7, score=152.2]; Homeodomain [PF00046.31, score=46.4]; Homeobox KN domain [PF05920.13, score=40.1]} {Human: ENSG00000184302, SIX6, SIX homeobox 6, [RH, Score=327, Expect=1e-109]; ENSG00000138083, SIX3, SIX homeobox 3, [RH, Score=325, Expect=7e-108]} {Mouse: ENSMUSG00000038805, Six3, sine oculis-related homeobox 3, [RH, Score=325, Expect=5e-108]; ENSMUSG00000021099, Six6, sine oculis-related homeobox 6, [RH, Score=323, Expect=2e-108]} {Dmel: FBgn0025360, Optix, [RH, Score=291, Expect=1e-92]} {Celegans: WBGene00000453, ceh-32, Homeobox protein ceh-32, [RH, Score=237, Expect=1e-72]} {Smed: dd_Smed_v6_11975_0_1, dd_Smed_v6_11975_0_1, [RH, Score=360, Expect=1e-119]} {RNA1509_39396} {RNA1310_25182.2} {RNA815_23127}
58. MligTC455_47476 7650 159.38 Mlig455_011139

Neo: -

Age: logFC(26M/2M)=-0.342

RSPH1 1.889 - - - 0.926 0.963 - Mlig455_011139 {REF} {Length: 1427} {Pfam: MORN repeat [PF02493.22, score=123.5]} {Human: ENSG00000160188, RSPH1, radial spoke head component 1, [RH, Score=256, Expect=6e-84]} {Mouse: ENSMUSG00000024033, Rsph1, radial spoke head 1 homolog (Chlamydomonas), [RH, Score=266, Expect=8e-88]} {Dmel: FBgn0032478, CG5458, [RH, Score=149, Expect=6e-42]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=59.3, Expect=1e-09]} {Smed: dd_Smed_v6_3321_0_1, dd_Smed_v6_3321_0_1, [RH, Score=306, Expect=6e-104]} {RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1310_22398, RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1509_10402, RNA1509_5779, RNA1509_6982, RNA815_10865}
59. MligTC455_50665 48 0.99 Mlig455_032812

Neo: -

Age: -

1.886 - - - 0.951 - 0.935 Mlig455_032812 {REF} {Length: 1550} {Pfam: Glycine rich protein [PF12810.9, score=23.7]} {RNA1310_48243.1} {RNA815_30313.2}
60. MligTC455_44810 226 4.72 Mlig455_013293, Mlig455_035940, Mlig455_058406, Mlig455_058409

Neo: -

Age: -

Region-specific R2: 6.204

Region-enriched R2: 5.509/0.00501

1.864 - - - 0.911 - 0.953

Mlig455_013293 {REF} {Length: 1362} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=56.6, Expect=2e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_035940 {REF} {Length: 1652} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058406 {REF} {Length: 991} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=4e-09]} {RNA1310_28961.1} {RNA815_27532}

Mlig455_058409 {REF} {Length: 1311} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
61. MligTC455_21640 262 5.46 Mlig455_052657

Neo: -

Age: -

SLC6A5 1.863 - - - 0.905 0.958 - Mlig455_052657 {REF} {Length: 4833} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=583.6]; BTB/POZ domain [PF00651.33, score=59.5]; BTB And C-terminal Kelch [PF07707.17, score=44.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=24.7]; Protein of unknown function (DUF2722) [PF10846.10, score=18.1]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=316, Expect=2e-92]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=315, Expect=5e-92]} {Dmel: FBgn0034911, CG5549, [Score=313, Expect=5e-89]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=228, Expect=2e-63]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=273, Expect=1e-78]} {RNA1509_27437} {RNA1310_7302.1} {RNA815_3821}
62. MligTC455_04786 26 0.55 Mlig455_043817, Mlig455_047431

Neo: -

Age: -

1.855 - - - 0.905 - 0.950

Mlig455_043817 {REF} {Length: 319} {NoTransDecoderORF} {RNA1310_64690}

Mlig455_047431 {REF} {Length: 2194} {Pfam: Glycine rich protein [PF12810.9, score=25.3]} {RNA1509_16377} {RNA1310_33363.2} {RNA815_25152}
63. MligTC455_44809 88 1.83 Mlig455_035938

Neo: -

Age: -

1.855 - - - 0.905 - 0.950 Mlig455_035938 {REF} {Length: 1369} {Smed: dd_Smed_v6_42798_0_1, dd_Smed_v6_42798_0_1, [Score=55.8, Expect=3e-09]} {RNA1310_28961.1} {RNA815_27532}
64. MligTC455_22688 18 0.37 Mlig455_030413

Neo: -

Age: -

GRIK3 1.851 - - - 0.892 - 0.959 Mlig455_030413 {REF} {Length: 3851} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=76.0]; Ligand-gated ion channel [PF00060.28, score=51.9]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=158, Expect=1e-40]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=153, Expect=7e-39]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=149, Expect=7e-38]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=149, Expect=6e-38]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=148, Expect=2e-37]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=142, Expect=1e-35]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=132, Expect=1e-32]} {Smed: dd_Smed_v6_4267_0_3, dd_Smed_v6_4267_0_3, [Score=149, Expect=5e-38]} {RNA1310_20394.1} {RNA815_45848}
65. MligTC455_48561 779 16.24 Mlig455_034702, Mlig455_034755

Neo: -

Age: -

FABP4 1.85 - - - 0.961 - 0.889

Mlig455_034702 {REF} {Length: 723} {Human: ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=43.9, Expect=8e-06]} {RNA1509_39777} {RNA1310_54956} {RNA815_27929.1}

Mlig455_034755 {REF} {Length: 924} {Human: ENSG00000170323, FABP4, fatty acid binding protein 4, [Score=43.9, Expect=8e-06]} {RNA1509_39777} {RNA1310_54956, RNA1509_39777} {RNA1509_39777, RNA815_27929.1}
66. MligTC455_26986 157 3.28 Mlig455_058044

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.496

1.848 - - - 0.889 0.959 - Mlig455_058044 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=51.3]; Ceramide kinase C-terminal domain [PF19280.1, score=22.6]} {Mouse: ENSMUSG00000075256, Cerkl, ceramide kinase-like, [Score=55.1, Expect=2e-07]} {Dmel: FBgn0037315, Cerk, Ceramide kinase, [Score=52.4, Expect=1e-06]} {RNA1509_33630, RNA1509_39108} {RNA1310_4577, RNA1509_33630, RNA1509_39108} {RNA1509_33630, RNA1509_39108, RNA815_1173}
67. MligTC455_43324 71 1.47 Mlig455_041984

Neo: -

Age: -

Region-enriched R2: 6.623/0.00573

1.843 - - - 0.887 - 0.956 Mlig455_041984 {REF} {Length: 388} {NoTransDecoderORF} {RNA1509_49821} {RNA1310_52560.2} {RNA815_59873}
68. MligTC455_38487 21 0.43 Mlig455_035154

Neo: -

Age: -

1.837 - - - 0.880 - 0.957 Mlig455_035154 {REF} {Length: 903} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=30.4]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=47.4, Expect=5e-06]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=50.8, Expect=4e-07]} {RNA1310_44717} {RNA815_43195}
69. MligTC455_53471 1325 27.61 Mlig455_015629

Neo: -

Age: logFC(26M/2M)=-0.386

CFAP65 1.828 - - - - 0.955 0.873 Mlig455_015629 {REF} {Length: 5817} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=93.0]; MSP (Major sperm protein) domain [PF00635.28, score=47.3]; Protein of unknown function (DUF1573) [PF07610.13, score=22.4]; Transmembrane protein 131-like N-terminal [PF12371.10, score=21.0]} {Human: ENSG00000181378, CFAP65, cilia and flagella associated protein 65, [RH, Score=850, Expect=0.0]} {Mouse: ENSMUSG00000047021, Cfap65, cilia and flagella associated protein 65, [RH, Score=844, Expect=0.0]} {Smed: dd_Smed_v6_12428_0_1, dd_Smed_v6_12428_0_1, [RH, Score=1276, Expect=0.0]} {RNA1509_19700} {RNA1310_760, RNA1509_19700} {RNA1509_19700, RNA815_222.1}
70. MligTC455_29915 50 1.04 Mlig455_027934

Neo: -

Age: Down-Up-Up

Region-enriched R2: 6.881/0.04464

ANGPTL1 1.822 - - - 0.867 - 0.955 Mlig455_027934 {REF} {Length: 2265} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=43.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=48.9, Expect=9e-06]} {Dmel: FBgn0031804, CG9500, [Score=53.1, Expect=9e-08]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=49.7, Expect=1e-06]} {RNA1509_53291} {RNA1310_38229.1} {RNA815_10579.1}
71. MligTC455_31663 23 0.48 Mlig455_013845

Neo: -

Age: -

1.808 - - - 0.956 - 0.852 Mlig455_013845 {REF} {Length: 1056} {RNA1310_32319} {RNA815_18072}
72. MligTC455_18479 293 6.11 Mlig455_029348

Neo: -

Age: -

Region-enriched R2: 2.256/0.00988

1.802 - - - - 0.952 0.850 Mlig455_029348 {REF} {Length: 2771} {Pfam: Leucine Rich repeat [PF13516.8, score=43.0]} {Mouse: ENSMUSG00000099564, Gm28729, predicted gene 28729, [RH, Score=125, Expect=4e-31]} {Smed: dd_Smed_v6_16437_0_1, dd_Smed_v6_16437_0_1, [RH, Score=268, Expect=2e-84]} {RNA1509_18255, RNA1509_55057} {RNA1310_16954, RNA1509_18255, RNA1509_55057} {RNA1509_18255, RNA1509_55057, RNA815_6360}
73. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

1.794 - - - - 0.844 0.950 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}
74. MligTC455_50146 37 0.77 Mlig455_050983

Neo: -

Age: -

NPSR1 1.788 - - - - 0.831 0.957 Mlig455_050983 {REF} {Length: 1326} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=105.5]} {Human: ENSG00000187258, NPSR1, neuropeptide S receptor 1, [Score=63.5, Expect=1e-10]} {Mouse: ENSMUSG00000029255, Gnrhr, gonadotropin releasing hormone receptor, [Score=66.6, Expect=4e-12]; ENSMUSG00000044014, Npy5r, neuropeptide Y receptor Y5, [Score=65.5, Expect=3e-11]} {Dmel: FBgn0036278, CrzR, Corazonin receptor, [Score=72.8, Expect=1e-13]} {Celegans: WBGene00013642, daf-38, G-protein coupled receptor daf-38, [Score=65.5, Expect=1e-11]} {Smed: dd_Smed_v6_75337_0_1, dd_Smed_v6_75337_0_1, [Score=66.6, Expect=2e-12]} {RNA1310_64751.2}
75. MligTC455_44578 12 0.24 Mlig455_048995

Neo: Int S/G2/M

Age: -

Region-enriched R2: 5.730/0.04221

1.783 - - - 0.828 - 0.955 Mlig455_048995 {REF} {Length: 2090} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=110.0]} {RNA1310_22174} {RNA815_24783}
76. MligTC455_37308 1663 34.65 Mlig455_040453

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.651

ARRDC1 1.777 - 0.792 - - 0.985 - Mlig455_040453 {REF} {Length: 2316} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.2]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=63.8]} {Human: ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=80.5, Expect=1e-15]; ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=78.6, Expect=7e-15]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=73.6, Expect=2e-13]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=90.9, Expect=1e-19]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.1, Expect=5e-11]} {RNA1509_2401, RNA1509_53571} {RNA1310_27725, RNA1509_53571} {RNA1509_53571, RNA815_11006.1}
77. MligTC455_26601 40 0.84 Mlig455_000748

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.661

1.777 - - - - 0.827 0.950 Mlig455_000748 {REF} {Length: 4122} {Smed: dd_Smed_v6_17076_0_2, dd_Smed_v6_17076_0_2, [Score=84.3, Expect=1e-17]} {RNA1310_16747.1} {RNA815_12493}
78. MligTC455_42513 70 1.45 Mlig455_023063, Mlig455_023065

Neo: -

Age: -

KCNC2 1.771 - - - - 0.816 0.955

Mlig455_023063 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}

Mlig455_023065 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}
79. MligTC455_32994 97 2.02 Mlig455_038103

Neo: -

Age: -

CFAP46 1.761 - - - 0.951 - 0.810 Mlig455_038103 {REF} {Length: 2310} {Human: ENSG00000171811, CFAP46, cilia and flagella associated protein 46, [Score=112, Expect=4e-25]} {Mouse: ENSMUSG00000049571, Cfap46, cilia and flagella associated protein 46, [Score=168, Expect=1e-43]} {Smed: dd_Smed_v6_14103_0_1, dd_Smed_v6_14103_0_1, [Score=157, Expect=3e-40]} {RNA1509_22612} {RNA1310_312.1} {RNA815_3411}
80. MligTC455_30023 17914 373.2 Mlig455_004073

Neo: -

Age: logFC(26M/2M)=-0.534

Region-enriched R2: 1.038/0.04465

CAV1 1.757 - - - 0.967 - 0.790 Mlig455_004073 {REF} {Length: 996} {Pfam: Caveolin [PF01146.19, score=125.9]} {Human: ENSG00000105974, CAV1, caveolin 1, [Score=106, Expect=6e-30]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [Score=104, Expect=3e-29]} {Celegans: WBGene00000301, cav-1, Caveolin-1, [RH, Score=84.3, Expect=7e-21]} {Smed: dd_Smed_v6_8555_0_1, dd_Smed_v6_8555_0_1, [RH, Score=150, Expect=6e-48]} {RNA1509_12190, RNA1509_37804, RNA1509_58757} {RNA1310_35724, RNA1509_12190, RNA1509_37804, RNA1509_58757} {RNA1509_12190, RNA1509_37804, RNA1509_58757, RNA815_6720.1}
81. MligTC455_38010 38 0.79 Mlig455_059485

Neo: -

Age: -

1.757 - - - 0.952 - 0.805 Mlig455_059485 {REF} {Length: 1213} {Pfam: Lectin C-type domain [PF00059.23, score=24.8]} {RNA1509_20946} {RNA1310_35102} {RNA815_16139}
82. MligTC455_39071 9672 201.49 Mlig455_015575

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.214

Region-enriched R2: 1.120/0.02700

GSTP1 1.743 - - - 0.956 - 0.787 Mlig455_015575 {REF} {Length: 1010} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=54.9]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=36.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=34.1]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=31.7]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=28.6]; Glutathione S-transferase N-terminal domain [PF17172.6, score=19.8]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=128, Expect=1e-36]} {Mouse: ENSMUSG00000097830, Gstp1, glutathione S-transferase, pi 1, [Score=137, Expect=3e-40]; ENSMUSG00000060803, Gstp1, glutathione S-transferase, pi 1, [Score=137, Expect=3e-40]; ENSMUSG00000097808, Gstp2, glutathione S-transferase, pi 2, [Score=133, Expect=1e-38]; ENSMUSG00000038155, Gstp2, glutathione S-transferase, pi 2, [Score=133, Expect=1e-38]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=83.6, Expect=2e-19]} {Celegans: WBGene00001773, gst-25, Glutathione S-Transferase, [RH, Score=139, Expect=2e-41]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=79.0, Expect=3e-18]} {RNA1509_2443, RNA1509_26611, RNA1509_31917, RNA1509_38325, RNA1509_49915, RNA1509_53866} {RNA1310_29579.1, RNA1509_2443, RNA1509_26611, RNA1509_31917, RNA1509_38325, RNA1509_49915, RNA1509_53866} {RNA1509_2443, RNA1509_26611, RNA1509_31917, RNA1509_38325, RNA1509_49915, RNA1509_53866, RNA815_15364.1}
83. MligTC455_51832 340 7.09 Mlig455_007654

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.194

1.739 - - - 0.782 0.957 - Mlig455_007654 {REF} {Length: 3430} {RNA1509_11544} {RNA1310_10250.1} {RNA815_17170}
84. MligTC455_43315 118 2.46 Mlig455_022312, Mlig455_069884

Neo: -

Age: logFC(26M/2M)=0.730

KREMEN2 1.732 - - - 0.776 - 0.956

Mlig455_022312 {REF} {Length: 2816} {Pfam: WSC domain [PF01822.21, score=54.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.1, Expect=5e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.4, Expect=3e-06]} {RNA1509_40165} {RNA1310_40900} {RNA815_15848}

Mlig455_069884 {REF} {Length: 2143} {Pfam: WSC domain [PF01822.21, score=54.1]} {Human: ENSG00000131650, KREMEN2, kringle containing transmembrane protein 2, [Score=52.0, Expect=2e-07]} {Mouse: ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=50.1, Expect=5e-07]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=63.9, Expect=1e-11]} {Celegans: WBGene00005024, sqv-6, Xylosyltransferase sqv-6, [Score=47.4, Expect=3e-06]} {RNA1509_40165} {RNA1310_40900} {RNA815_15848}
85. MligTC455_53211 1358 28.3 Mlig455_040065, Mlig455_040091

Neo: -

Age: logFC(26M/2M)=-0.362

Region-enriched R4: 1.888/0.01442

1.731 - - - 0.768 0.963 -

Mlig455_040065 {REF} {Length: 3189} {RNA1509_49542, RNA1509_9168} {RNA1310_8796.1, RNA1509_49542, RNA1509_9168} {RNA1509_49542, RNA1509_9168, RNA815_3100}

Mlig455_040091 {REF} {Length: 2759} {RNA1509_39791, RNA1509_9168} {RNA1310_8796.1, RNA1509_39791} {RNA1509_39791, RNA815_3100}
86. MligTC455_17299 538 11.21 Mlig455_036559, Mlig455_057787

Neo: -

Age: -

Region-enriched R2: 5.046/0.00000
Region-enriched R3: 3.527/0.00004

1.729 - - - 0.779 - 0.950

Mlig455_036559 {REF} {Length: 718} {RNA1509_57277} {RNA1310_52579, RNA1509_57277} {RNA1509_57277, RNA815_26706}

Mlig455_057787 {REF} {Length: 741} {RNA1509_57277} {RNA1310_52579} {RNA815_26706}
87. MligTC455_23589 1204 25.08 Mlig455_013096, Mlig455_013189

Neo: -

Age: -

CNBD1 1.726 - 0.771 - - 0.955 -

Mlig455_013096 {REF} {Length: 1719} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.0]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=213, Expect=2e-63]} {RNA1509_35878} {RNA1310_17903} {RNA815_7217}

Mlig455_013189 {REF} {Length: 1713} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.1]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=212, Expect=5e-63]} {RNA1509_35878} {RNA1310_17903, RNA1509_35878} {RNA1509_35878, RNA815_7217}
88. MligTC455_51833 355 7.4 Mlig455_020965

Neo: Int S/G2/M

Age: Down-Down-Up

1.723 - - - 0.769 0.954 - Mlig455_020965 {REF} {Length: 3849} {RNA1509_11544} {RNA1310_10250.1} {RNA815_27684}
89. MligTC455_45020 386 8.05 Mlig455_012422

Neo: -

Age: -

Region-enriched R2: 4.067/0.00066
Region-enriched R3: 2.869/0.01291

AVP 1.717 - - - - 0.758 0.959 Mlig455_012422 {REF} {Length: 1252} {Pfam: Neurohypophysial hormones, C-terminal Domain [PF00184.19, score=36.0]} {Human: ENSG00000101200, AVP, arginine vasopressin, [Score=50.4, Expect=4e-08]} {Mouse: ENSMUSG00000037727, Avp, arginine vasopressin, [Score=52.0, Expect=7e-09]} {RNA1509_50574} {RNA1310_26737, RNA1509_50574} {RNA1509_50574, RNA815_23813}
90. MligTC455_52987 980 20.41 Mlig455_054765

Neo: -

Age: logFC(26M/2M)=-0.758

Region-enriched R2: 2.188/0.00290

CALM3 1.716 - - - 0.956 - 0.760 Mlig455_054765 {REF} {Length: 759} {Pfam: EF hand [PF00036.34, score=109.0]; EF-hand domain pair [PF13499.8, score=105.1]; EF-hand domain [PF13405.8, score=89.0]; EF-hand domain pair [PF13833.8, score=88.7]; EF hand [PF13202.8, score=71.3]; EF-hand domain [PF14658.8, score=42.3]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=39.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=28.8]; EF-hand domain [PF08976.13, score=27.1]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=164, Expect=3e-52]; ENSG00000198668, CALM1, calmodulin 1, [Score=164, Expect=3e-52]; ENSG00000143933, CALM2, calmodulin 2, [Score=164, Expect=3e-52]} {Mouse: ENSMUSG00000019370, Calm3, calmodulin 3, [Score=164, Expect=2e-52]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=164, Expect=2e-52]; ENSMUSG00000001175, Calm1, calmodulin 1, [Score=164, Expect=2e-52]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=159, Expect=2e-50]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=164, Expect=3e-52]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=164, Expect=2e-52]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=164, Expect=2e-52]} {RNA1509_6221} {RNA1310_49203} {RNA815_22421}
91. MligTC455_44713 661 13.77 Mlig455_048154

Neo: -

Age: logFC(26M/2M)=0.569

Region-specific R2: 3.883

Region-enriched R2: 3.422/0.00000

1.711 - - - - 0.751 0.960 Mlig455_048154 {REF} {Length: 1173} {RNA1509_34252} {RNA1310_54269.1} {RNA815_55074}
92. MligTC455_17049 6274 130.71 Mlig455_029792, Mlig455_029942

Neo: -

Age: logFC(26M/2M)=-0.392

EFCAB2 1.709 - - - 0.757 - 0.952

Mlig455_029792 {REF} {Length: 935} {Pfam: EF-hand domain pair [PF13499.8, score=44.0]; EF-hand domain [PF13405.8, score=39.7]; EF hand [PF00036.34, score=28.8]; EF-hand domain [PF14658.8, score=24.5]} {Human: ENSG00000203666, EFCAB2, EF-hand calcium binding domain 2, [RH, Score=204, Expect=8e-67]} {Mouse: ENSMUSG00000026495, Efcab2, EF-hand calcium binding domain 2, [RH, Score=209, Expect=9e-70]} {Dmel: FBgn0034481, CG11041, [RH, Score=139, Expect=1e-42]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.0, Expect=3e-20]} {Smed: dd_Smed_v6_11976_0_1, dd_Smed_v6_11976_0_1, [RH, Score=192, Expect=1e-63]} {RNA1509_6027, RNA1509_9780} {RNA1310_41624, RNA1509_6027, RNA1509_9780} {RNA1509_6027, RNA1509_9780, RNA815_18008}

Mlig455_029942 {REF} {Length: 933} {Pfam: EF-hand domain pair [PF13499.8, score=44.0]; EF-hand domain [PF13405.8, score=39.7]; EF hand [PF00036.34, score=28.8]; EF-hand domain [PF14658.8, score=24.5]} {Human: ENSG00000203666, EFCAB2, EF-hand calcium binding domain 2, [RH, Score=204, Expect=8e-67]} {Mouse: ENSMUSG00000026495, Efcab2, EF-hand calcium binding domain 2, [RH, Score=209, Expect=9e-70]} {Dmel: FBgn0034481, CG11041, [RH, Score=139, Expect=1e-42]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=82.0, Expect=3e-20]} {Smed: dd_Smed_v6_11976_0_1, dd_Smed_v6_11976_0_1, [RH, Score=192, Expect=1e-63]} {RNA1509_6027} {RNA1310_41624} {RNA815_18008}
93. MligTC455_22686 26 0.55 Mlig455_000566, Mlig455_030366

Neo: -

Age: -

GRIK3 1.707 - - - 0.750 - 0.957

Mlig455_000566 {REF} {Length: 2943} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=78.1]; Ligand-gated ion channel [PF00060.28, score=52.0]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=48.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=157, Expect=5e-39]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=154, Expect=6e-38]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=154, Expect=7e-38]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=152, Expect=2e-37]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=151, Expect=4e-37]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=150, Expect=4e-37]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=145, Expect=2e-35]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=147, Expect=4e-36]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=137, Expect=4e-33]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=155, Expect=5e-39]} {RNA1310_20394.1} {RNA815_45848}

Mlig455_030366 {REF} {Length: 2933} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=78.1]; Ligand-gated ion channel [PF00060.28, score=51.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=48.7]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=157, Expect=4e-39]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=154, Expect=5e-38]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=152, Expect=2e-37]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=151, Expect=4e-37]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=150, Expect=5e-37]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=150, Expect=4e-37]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=145, Expect=3e-35]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=144, Expect=9e-35]} {Dmel: FBgn0039916, Ekar, Eye-enriched kainate receptor, [Score=147, Expect=5e-36]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=137, Expect=5e-33]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=154, Expect=1e-38]} {RNA1310_20394.1} {RNA815_45848}
94. MligTC455_31117 933 19.44 Mlig455_017721, Mlig455_057064, Mlig455_057078

Neo: -

Age: logFC(26M/2M)=-0.670

Region-enriched R2: 1.818/0.04375

ADAM33, ADAM9 1.7 - - - 0.962 0.738 -

Mlig455_017721 {REF} {Length: 3292} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=127.8]; Metallo-peptidase family M12 [PF13688.8, score=71.8]; Disintegrin [PF00200.25, score=68.3]; ADAM cysteine-rich [PF08516.14, score=60.1]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=40.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.1]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=30.2]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=244, Expect=5e-69]} {Mouse: ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [RH, Score=254, Expect=3e-73]; ENSMUSG00000050190, Gm5346, predicted gene 5346, [RH, Score=251, Expect=7e-72]} {Dmel: FBgn0265140, Meltrin, [Score=272, Expect=3e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [RH, Score=251, Expect=5e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=225, Expect=1e-61]} {RNA1509_21514, RNA1509_7654} {RNA1310_9319.1, RNA1509_21514, RNA1509_7654} {RNA1509_21514, RNA1509_7654, RNA815_4173.1}

Mlig455_057064 {REF} {Length: 3604} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=128.4]; Metallo-peptidase family M12 [PF13688.8, score=69.3]; Disintegrin [PF00200.25, score=68.6]; ADAM cysteine-rich [PF08516.14, score=60.7]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=42.0]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=37.2]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=31.5]; Matrixin [PF00413.26, score=19.9]} {Human: ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [RH, Score=247, Expect=9e-71]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=256, Expect=1e-74]} {Dmel: FBgn0265140, Meltrin, [Score=270, Expect=2e-78]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=248, Expect=7e-71]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=226, Expect=7e-63]} {RNA1509_44914} {RNA1310_9319.1, RNA1509_44914} {RNA1509_44914, RNA815_4173.1}

Mlig455_057078 {REF} {Length: 1339} {Pfam: ADAM cysteine-rich [PF08516.14, score=75.6]; Disintegrin [PF00200.25, score=53.3]} {Human: ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=145, Expect=6e-38]; ENSG00000168594, ADAM29, ADAM metallopeptidase domain 29, [Score=145, Expect=1e-37]; ENSG00000139985, ADAM21, ADAM metallopeptidase domain 21, [Score=143, Expect=5e-37]; ENSG00000143537, ADAM15, ADAM metallopeptidase domain 15, [Score=142, Expect=8e-37]} {Mouse: ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=137, Expect=5e-35]; ENSMUSG00000028041, Adam15, a disintegrin and metallopeptidase domain 15 (metargidin), [Score=137, Expect=3e-35]; ENSMUSG00000011256, Adam19, a disintegrin and metallopeptidase domain 19 (meltrin beta), [Score=137, Expect=3e-35]; ENSMUSG00000046258, Adam29, a disintegrin and metallopeptidase domain 29, [Score=137, Expect=3e-35]; ENSMUSG00000008438, Adam21, a disintegrin and metallopeptidase domain 21, [Score=135, Expect=2e-34]; ENSMUSG00000079058, Adam34, a disintegrin and metallopeptidase domain 34, [Score=134, Expect=5e-34]; ENSMUSG00000062438, Adam1b, a disintegrin and metallopeptidase domain 1b, [Score=134, Expect=3e-34]; ENSMUSG00000031553, Adam3, a disintegrin and metallopeptidase domain 3 (cyritestin), [Score=133, Expect=1e-33]; ENSMUSG00000063900, Adam26b, a disintegrin and metallopeptidase domain 26B, [Score=131, Expect=3e-33]} {Dmel: FBgn0265140, Meltrin, [Score=153, Expect=1e-40]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=133, Expect=6e-34]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=132, Expect=1e-33]} {RNA1509_44914} {RNA1310_9319.1} {RNA815_4173.1}
95. MligTC455_33636 175 3.64 Mlig455_027209, Mlig455_050659

Neo: -

Age: logFC(26M/2M)=-0.416

Region-enriched R2: 3.904/0.00709
Region-enriched R3: 2.835/0.03879

CHRNA10 1.7 0.749 - - - - 0.951

Mlig455_027209 {REF} {Length: 1614} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=99.8]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=74.0]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=152, Expect=1e-40]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=150, Expect=8e-40]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=149, Expect=2e-39]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=149, Expect=2e-39]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=148, Expect=6e-39]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=150, Expect=3e-40]; ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=150, Expect=5e-40]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=144, Expect=5e-38]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=133, Expect=1e-33]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=142, Expect=3e-37]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=142, Expect=3e-37]} {RNA1310_19147.1} {RNA815_8553.1}

Mlig455_050659 {REF} {Length: 1670} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=93.6]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=69.9]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=148, Expect=2e-39]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=144, Expect=1e-37]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=141, Expect=1e-36]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=148, Expect=1e-39]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=141, Expect=9e-37]} {Dmel: FBgn0004118, nAChRbeta2, nicotinic Acetylcholine Receptor beta2, [Score=134, Expect=4e-34]} {Celegans: WBGene00000048, acr-9, AcetylCholine Receptor, [Score=144, Expect=7e-38]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=141, Expect=6e-37]} {RNA1310_19147.1} {RNA815_8553.1}
96. MligTC455_19079 218 4.54 Mlig455_008746, Mlig455_008760

Neo: -

Age: Down-Up-Up

Region-specific R2: 6.705

Region-enriched R2: 6.864/0.00152

1.692 - - - - 0.733 0.959

Mlig455_008746 {REF} {Length: 652} {RNA1310_75395.1} {RNA815_42524}

Mlig455_008760 {REF} {Length: 1051} {RNA1310_75395.1} {RNA815_42524}
97. MligTC455_36544 2585 53.85 Mlig455_064488

Neo: -

Age: logFC(26M/2M)=-0.301

CALM2 1.692 - - 0.737 - - 0.955 Mlig455_064488 {REF} {Length: 1179} {Pfam: EF-hand domain pair [PF13499.8, score=88.6]; EF hand [PF00036.34, score=77.3]; EF-hand domain pair [PF13833.8, score=74.0]; EF-hand domain [PF13405.8, score=58.5]; EF hand [PF13202.8, score=44.5]; EF-hand domain [PF14658.8, score=42.3]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.6]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=143, Expect=2e-43]; ENSG00000198668, CALM1, calmodulin 1, [Score=140, Expect=7e-43]; ENSG00000160014, CALM3, calmodulin 3, [Score=140, Expect=8e-43]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=140, Expect=5e-43]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=140, Expect=5e-43]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=140, Expect=5e-43]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=136, Expect=2e-41]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=139, Expect=1e-42]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=139, Expect=1e-42]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=139, Expect=8e-43]} {RNA1509_12275, RNA1509_21777} {RNA1310_34886, RNA1509_12275, RNA1509_21777} {RNA1509_12275, RNA1509_21777, RNA815_16051.1}
98. MligTC455_53546 130 2.72 Mlig455_013326, Mlig455_013334

Neo: -

Age: -

Region-enriched R2: 6.753/0.01892

MMP9 1.691 0.733 - - - - 0.958

Mlig455_013326 {REF} {Length: 1449} {Pfam: Fibronectin type II domain [PF00040.21, score=92.5]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=87.8, Expect=3e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=82.4, Expect=1e-16]; ENSMUSG00000031740, Mmp2, matrix metallopeptidase 2, [RH, Score=78.6, Expect=2e-15]} {Smed: dd_Smed_v6_14558_0_1, dd_Smed_v6_14558_0_1, [RH, Score=138, Expect=3e-38]} {RNA1310_38631} {RNA815_51136}

Mlig455_013334 {REF} {Length: 1398} {Pfam: Fibronectin type II domain [PF00040.21, score=92.1]} {Human: ENSG00000100985, MMP9, matrix metallopeptidase 9, [RH, Score=89.4, Expect=1e-18]} {Mouse: ENSMUSG00000017737, Mmp9, matrix metallopeptidase 9, [RH, Score=84.0, Expect=4e-17]} {Smed: dd_Smed_v6_12601_0_1, dd_Smed_v6_12601_0_1, [RH, Score=140, Expect=2e-38]} {RNA1310_38631} {RNA815_51136}
99. MligTC455_31001 1473 30.69 Mlig455_024877, Mlig455_068443

Neo: -

Age: -

Region-enriched R8: 2.076/0.01787

MPEG1 1.688 - - - 0.738 0.950 -

Mlig455_024877 {REF} {Length: 3371} {Pfam: MAC/Perforin domain [PF01823.21, score=139.0]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=362, Expect=4e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=368, Expect=2e-110]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=355, Expect=1e-106]} {RNA1509_21688, RNA1509_30083, RNA1509_44998, RNA1509_4699} {RNA1310_4591, RNA1509_21688, RNA1509_30083, RNA1509_44998} {RNA1509_21688, RNA1509_30083, RNA1509_44998, RNA815_1433.1}

Mlig455_068443 {REF} {Length: 5971} {Pfam: MAC/Perforin domain [PF01823.21, score=139.0]} {Human: ENSG00000197629, MPEG1, macrophage expressed 1, [RH, Score=362, Expect=4e-108]} {Mouse: ENSMUSG00000046805, Mpeg1, macrophage expressed gene 1, [RH, Score=368, Expect=2e-110]} {Smed: dd_Smed_v6_983_0_1, dd_Smed_v6_983_0_1, [RH, Score=355, Expect=1e-106]} {RNA1509_4699} {RNA1310_4591} {RNA815_1433.1}
100. MligTC455_24472 738 15.38 Mlig455_039540

Neo: -

Age: Up-Down-Down

CSMD2 1.686 - 0.735 - 0.951 - - Mlig455_039540 {REF} {Length: 18394} {Pfam: Sushi repeat (SCR repeat) [PF00084.22, score=107.2]; CUB domain [PF00431.22, score=96.4]; Calcium-binding EGF domain [PF07645.17, score=47.4]; Complement Clr-like EGF-like [PF12662.9, score=23.2]; Coagulation Factor Xa inhibitory site [PF14670.8, score=22.1]} {Human: ENSG00000121904, CSMD2, CUB and Sushi multiple domains 2, [Score=103, Expect=8e-21]} {Mouse: ENSMUSG00000060924, Csmd1, CUB and Sushi multiple domains 1, [Score=97.1, Expect=5e-19]; ENSMUSG00000022311, Csmd3, CUB and Sushi multiple domains 3, [Score=95.5, Expect=2e-18]; ENSMUSG00000028804, Csmd2, CUB and Sushi multiple domains 2, [Score=93.6, Expect=6e-18]} {Dmel: FBgn0031879, uif, uninflatable, [Score=207, Expect=1e-52]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=210, Expect=1e-53]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=77.4, Expect=1e-13]} {RNA1509_104, RNA1509_1720} {RNA1310_11.1, RNA1509_104} {RNA1509_104, RNA815_7}

There are 44 more genes with r >= 0.95  Show all


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