M. lignano Tomo-Seq
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Results for MligTC455_23638

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_23638 20 0.41 Mlig455_025868, Mlig455_025928, Mlig455_025959

Neo: -

Age: Up-Down-Down

Mlig455_025868 {REF} {Length: 1158} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=55.1]} {RNA1310_78629}

Mlig455_025928 {REF} {Length: 3552} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=130.7]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=67.8, Expect=9e-12]} {RNA1310_55747}

Mlig455_025959 {REF} {Length: 1931} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=129.3]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=68.9, Expect=4e-12]} {RNA1310_55747}

Cumulative graph for MligTC455_23638

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -2.842 0.779 0.41758 1.00000
RegionR2 0.644 0.779 0.40003 0.79434
RegionR3 -0.451 0.779 0.98428 1.00000
RegionR4 -0.059 0.779 1.00000 1.00000
RegionR5 -2.867 0.779 1.00000 1.00000
RegionR6 -1.466 0.779 0.99950 1.00000
RegionR7 4.462 0.779 0.00299 0.07662
RegionR8 2.577 0.779 0.19428 0.78913

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.475 0.779 0.99992 1.00000
RegenerationR2 2.016 0.779 0.72973 0.96560
RegenerationR3 -1.628 0.779 0.38341 0.79195
RegenerationR4 -2.919 0.779 0.19982 0.64594
RegenerationR5 1.749 0.779 0.53583 0.87726
RegenerationR6 -1.029 0.779 0.43026 0.75810
RegenerationBL 0.552 0.779 0.66694 1.00000
RegenerationTP -3.896 0.779 0.26382 0.71201


Genes with expression patterns similar to MligTC455_23638

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_23638 20 0.41 Mlig455_025868, Mlig455_025928, Mlig455_025959

Neo: -

Age: Up-Down-Down

 1 - - - - 1.000 -

Mlig455_025868 {REF} {Length: 1158} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=55.1]} {RNA1310_78629}

Mlig455_025928 {REF} {Length: 3552} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=130.7]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=67.8, Expect=9e-12]} {RNA1310_55747}

Mlig455_025959 {REF} {Length: 1931} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=129.3]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [Score=68.9, Expect=4e-12]} {RNA1310_55747}
2. MligTC455_08352 14 0.29 Mlig455_017214

Neo: Irradiation

Age: Down-Down-Up

 APEX1 0.977 - - - - 0.977 - Mlig455_017214 {REF} {Length: 1458} {TRANSSPLICED} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=69.4]; Endonuclease-reverse transcriptase [PF14529.8, score=24.9]} {Human: ENSG00000100823, APEX1, apurinic/apyrimidinic endodeoxyribonuclease 1, [RH, Score=305, Expect=2e-100]} {Mouse: ENSMUSG00000035960, Apex1, apurinic/apyrimidinic endonuclease 1, [RH, Score=310, Expect=1e-102]} {Dmel: FBgn0004584, Rrp1, Recombination repair protein 1, [RH, Score=302, Expect=3e-95]} {Celegans: WBGene00001372, exo-3, DNA-(apurinic or apyrimidinic site) lyase, [RH, Score=238, Expect=3e-75]} {Smed: dd_Smed_v6_11417_0_1, dd_Smed_v6_11417_0_1, [RH, Score=338, Expect=8e-114]} {RNA1509_16413} {RNA1310_25554} {RNA815_11218.1}
3. MligTC455_29808 204 4.26 Mlig455_056288

Neo: Int S/G2/M

Age: -

Region-enriched R4: 3.556/0.04090

 MCM3AP 0.973 - - - - 0.973 - Mlig455_056288 {REF} {Length: 6365} {Pfam: SAC3/GANP family [PF03399.18, score=315.0]} {Human: ENSG00000160294, MCM3AP, minichromosome maintenance complex component 3 associated protein, [RH, Score=330, Expect=2e-91]} {Mouse: ENSMUSG00000001150, Mcm3ap, minichromosome maintenance complex component 3 associated protein, [RH, Score=328, Expect=7e-91]} {Dmel: FBgn0028974, xmas-2, [RH, Score=289, Expect=3e-79]} {Celegans: WBGene00017642, F20D12.2, [RH, Score=210, Expect=7e-55]} {Smed: dd_Smed_v6_10065_0_1, dd_Smed_v6_10065_0_1, [RH, Score=273, Expect=3e-75]} {RNA1509_12513} {RNA1310_1606} {RNA815_453.1}
4. MligTC455_38875 37 0.78 Mlig455_029375, Mlig455_029415

Neo: -

Age: logFC(26M/2M)=-0.939

 GRIK2 0.971 - - - - 0.971 -

Mlig455_029375 {REF} {Length: 3713} {Pfam: Ligand-gated ion channel [PF00060.28, score=88.9]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=58.3]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=34.5]; Receptor family ligand binding region [PF01094.30, score=20.4]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=136, Expect=2e-32]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=137, Expect=9e-33]} {Dmel: FBgn0038837, CG3822, [Score=150, Expect=4e-37]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=126, Expect=1e-29]} {Smed: dd_Smed_v6_21015_0_1, dd_Smed_v6_21015_0_1, [Score=242, Expect=3e-72]} {RNA1310_67049} {RNA815_49856}

Mlig455_029415 {REF} {Length: 2520} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=25.5]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=73.9, Expect=5e-14]} {RNA1310_74947} {RNA815_49856}
5. MligTC455_03405 22 0.46 Mlig455_055645

Neo: -

Age: -

Region-enriched R4: 3.600/0.04744

 0.966 - - - - 0.966 - Mlig455_055645 {REF} {Length: 458} {RNA1509_12042} {RNA1310_1137.2} {RNA815_55711}
6. MligTC455_10809 13 0.27 Mlig455_033725

Neo: -

Age: -

 0.965 - - - - 0.965 - Mlig455_033725 {REF} {Length: 627} {NoTransDecoderORF} {RNA1310_115069} {RNA815_52668}
7. MligTC455_28598 102 2.13 Mlig455_057552

Neo: -

Age: -

 0.96 - - - - 0.960 - Mlig455_057552 {REF} {Length: 3851} {TRANSSPLICED} {RNA1509_60109} {RNA1310_21727} {RNA815_11299}
8. MligTC455_43789 48 0.99 Mlig455_029925

Neo: -

Age: -

 FARP1 0.954 - - - - 0.954 - Mlig455_029925 {REF} {Length: 2354} {Pfam: PH domain [PF00169.31, score=54.9]; RhoGEF domain [PF00621.22, score=25.8]} {Human: ENSG00000152767, FARP1, FERM, ARH/RhoGEF and pleckstrin domain protein 1, [Score=153, Expect=2e-38]} {Mouse: ENSMUSG00000034066, Farp2, FERM, RhoGEF and pleckstrin domain protein 2, [Score=151, Expect=7e-38]; ENSMUSG00000025555, Farp1, FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived), [Score=149, Expect=3e-37]} {Dmel: FBgn0265082, Cdep, Chondrocyte-derived ezrin-like domain containing protein, [Score=118, Expect=2e-27]} {Celegans: WBGene00001490, frm-3, FERM domain (Protein4.1-ezrin-radixin-moesin) family, [Score=91.7, Expect=3e-19]} {Smed: dd_Smed_v6_14700_0_1, dd_Smed_v6_14700_0_1, [Score=154, Expect=2e-39]} {RNA1509_30091} {RNA1310_43814.1} {RNA815_20350}

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