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Results for MligTC455_25217

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_25217 983 20.49 Mlig455_014480

Neo: -

Age: logFC(26M/2M)=-0.277

 FHAD1 Mlig455_014480 {REF} {Length: 4999} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=39.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=24.9]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [RH, Score=215, Expect=9e-56]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [RH, Score=182, Expect=1e-45]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [RH, Score=182, Expect=1e-45]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=346, Expect=1e-98]} {RNA1509_3924} {RNA1310_1575.2} {RNA815_2279}

Cumulative graph for MligTC455_25217

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.377 4.383 0.69981 1.00000
RegionR2 0.956 4.383 0.01900 0.14817
RegionR3 -0.127 4.383 0.71547 1.00000
RegionR4 -0.138 4.383 0.74595 1.00000
RegionR5 -0.887 4.383 0.01073 0.06075
RegionR6 -0.203 4.383 0.57315 1.00000
RegionR7 -0.25 4.383 0.61220 1.00000
RegionR8 0.272 4.383 0.63340 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.791 4.383 0.48475 1.00000
RegenerationR2 0.474 4.383 0.14945 0.58269
RegenerationR3 0.644 4.383 0.10472 0.51238
RegenerationR4 0.217 4.383 0.59923 0.91302
RegenerationR5 0.476 4.383 0.23558 0.66929
RegenerationR6 0.072 4.383 0.86436 1.00000
RegenerationBL -0.167 4.383 0.73925 1.00000
RegenerationTP -0.402 4.383 0.46388 0.87678


Genes with expression patterns similar to MligTC455_25217

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_25217 983 20.49 Mlig455_014480

Neo: -

Age: logFC(26M/2M)=-0.277

 FHAD1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_014480 {REF} {Length: 4999} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=39.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=24.9]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [RH, Score=215, Expect=9e-56]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [RH, Score=182, Expect=1e-45]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [RH, Score=182, Expect=1e-45]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=346, Expect=1e-98]} {RNA1509_3924} {RNA1310_1575.2} {RNA815_2279}
2. MligTC455_53472 864 17.99 Mlig455_062449

Neo: -

Age: logFC(26M/2M)=-0.311

 CFAP65 4.299 - 0.720 0.954 0.873 0.852 0.900 Mlig455_062449 {REF} {Length: 5820} {Pfam: Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin [PF15780.7, score=92.3]; MSP (Major sperm protein) domain [PF00635.28, score=45.2]; Transmembrane protein 131-like N-terminal [PF12371.10, score=24.9]; Protein of unknown function (DUF1573) [PF07610.13, score=23.0]} {Human: ENSG00000181378, CFAP65, cilia and flagella associated protein 65, [RH, Score=850, Expect=0.0]} {Mouse: ENSMUSG00000047021, Cfap65, cilia and flagella associated protein 65, [RH, Score=842, Expect=0.0]} {Smed: dd_Smed_v6_12428_0_1, dd_Smed_v6_12428_0_1, [RH, Score=1277, Expect=0.0]} {RNA1509_19700, RNA1509_38302, RNA1509_57456} {RNA1310_760, RNA1509_38302, RNA1509_57456} {RNA1509_38302, RNA1509_57456, RNA815_222.1}
3. MligTC455_22235 6787 141.4 Mlig455_032864

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.356

 EFHC2 3.364 - 0.774 0.887 - 0.956 0.747 Mlig455_032864 {REF} {Length: 3541} {Pfam: DUF1126 PH-like domain [PF06565.14, score=338.3]; EF hand [PF00036.34, score=18.1]} {Human: ENSG00000183690, EFHC2, EF-hand domain containing 2, [RH, Score=657, Expect=0.0]} {Mouse: ENSMUSG00000025038, Efhc2, EF-hand domain (C-terminal) containing 2, [RH, Score=663, Expect=0.0]} {Dmel: FBgn0034487, Efhc1.2, EF-hand domain containing 1.2, [RH, Score=417, Expect=7e-135]} {Celegans: WBGene00013028, efhc-1, EF-Hand domain-Containing protein 1 homolog, [Score=97.8, Expect=3e-21]} {Smed: dd_Smed_v6_6035_0_1, dd_Smed_v6_6035_0_1, [RH, Score=829, Expect=0.0]} {RNA1509_6224, RNA1509_965} {RNA1310_5674, RNA1509_965} {RNA1509_965, RNA815_1927.1}
4. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

 MX2 3.35 - 0.746 - 0.729 0.921 0.954 Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
5. MligTC455_25532 631 13.14 Mlig455_000168

Neo: -

Age: -

 3.2 0.725 0.704 - - 0.806 0.965 Mlig455_000168 {REF} {Length: 1851} {TRANSSPLICED} {Pfam: Lectin C-type domain [PF00059.23, score=32.8]} {RNA1509_57829} {RNA1310_16312} {RNA815_15052}
6. MligTC455_05193 189 3.94 Mlig455_013094

Neo: -

Age: Down-Up-Down

 BCHE 2.706 0.853 - - - 0.869 0.984 Mlig455_013094 {REF} {Length: 2979} {Pfam: Carboxylesterase family [PF00135.30, score=435.7]; alpha/beta hydrolase fold [PF07859.15, score=35.5]} {Human: ENSG00000114200, BCHE, butyrylcholinesterase, [RH, Score=319, Expect=5e-100]} {Mouse: ENSMUSG00000027792, Bche, butyrylcholinesterase, [RH, Score=334, Expect=3e-105]} {Dmel: FBgn0000024, Ace, Acetylcholine esterase, [Score=253, Expect=3e-74]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [RH, Score=332, Expect=2e-104]} {Smed: dd_Smed_v6_15930_0_1, dd_Smed_v6_15930_0_1, [RH, Score=416, Expect=5e-136]} {RNA1509_5880} {RNA1310_9146.1} {RNA815_3169.2}
7. MligTC455_40019 7651 159.4 Mlig455_008768

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.383

 ODF3 2.689 - 0.913 - - 0.957 0.819 Mlig455_008768 {REF} {Length: 2865} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=66.8]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=185, Expect=1e-57]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=180, Expect=1e-55]} {Dmel: FBgn0032010, CG8086, [RH, Score=120, Expect=8e-33]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=330, Expect=3e-115]} {RNA1509_29531, RNA1509_587} {RNA1310_15447.1, RNA1509_29531} {RNA1509_29531, RNA815_2683.1}
8. MligTC455_40020 7894 164.45 Mlig455_008800

Neo: -

Age: -

 ODF3 2.684 - 0.903 - - 0.969 0.812 Mlig455_008800 {REF} {Length: 1876} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=67.2]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=186, Expect=4e-58]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [RH, Score=181, Expect=3e-56]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=3e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=331, Expect=1e-115]} {RNA1509_24509, RNA1509_25204, RNA1509_33091, RNA1509_587} {RNA1310_15447.1, RNA1509_24509, RNA1509_25204, RNA1509_33091, RNA1509_587} {RNA1509_24509, RNA1509_25204, RNA1509_33091, RNA1509_587, RNA815_2683.1}
9. MligTC455_48051 729 15.19 Mlig455_037292, Mlig455_037331

Neo: -

Age: logFC(26M/2M)=-0.645

Region-enriched R2: 2.891/0.00005

 AGBL3 2.68 - - - 0.962 0.853 0.865

Mlig455_037292 {REF} {Length: 4360} {Pfam: Zinc carboxypeptidase [PF00246.26, score=66.0]; Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=64.0]} {Human: ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [Score=547, Expect=1e-176]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [Score=521, Expect=5e-167]; ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [Score=521, Expect=5e-167]} {Mouse: ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [Score=542, Expect=9e-174]; ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [Score=528, Expect=5e-170]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=489, Expect=3e-157]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=276, Expect=6e-77]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [Score=533, Expect=2e-171]} {RNA1509_25820} {RNA1310_2132.1} {RNA815_1862}

Mlig455_037331 {REF} {Length: 4775} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=70.1]; Zinc carboxypeptidase [PF00246.26, score=65.7]} {Human: ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [RH, Score=575, Expect=0.0]} {Mouse: ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [RH, Score=569, Expect=0.0]; ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [RH, Score=568, Expect=0.0]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [Score=520, Expect=2e-168]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=290, Expect=1e-81]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [RH, Score=604, Expect=0.0]} {RNA1509_25820} {RNA1310_2132.1} {RNA815_1862}
10. MligTC455_22234 6560 136.67 Mlig455_006130

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.373

 EFHC2 2.671 - - 0.867 - 0.961 0.843 Mlig455_006130 {REF} {Length: 3115} {Pfam: DUF1126 PH-like domain [PF06565.14, score=338.3]; EF hand [PF00036.34, score=18.1]} {Human: ENSG00000183690, EFHC2, EF-hand domain containing 2, [RH, Score=658, Expect=0.0]} {Mouse: ENSMUSG00000025038, Efhc2, EF-hand domain (C-terminal) containing 2, [RH, Score=664, Expect=0.0]} {Dmel: FBgn0034487, Efhc1.2, EF-hand domain containing 1.2, [RH, Score=418, Expect=3e-135]} {Celegans: WBGene00013028, efhc-1, EF-Hand domain-Containing protein 1 homolog, [Score=97.8, Expect=2e-21]} {Smed: dd_Smed_v6_6035_0_1, dd_Smed_v6_6035_0_1, [RH, Score=830, Expect=0.0]} {RNA1509_10098, RNA1509_25996, RNA1509_36596, RNA1509_6224, RNA1509_7453} {RNA1310_5674, RNA1509_10098, RNA1509_25996, RNA1509_36596, RNA1509_6224, RNA1509_7453} {RNA1509_10098, RNA1509_25996, RNA1509_36596, RNA1509_6224, RNA1509_7453, RNA815_1927.1}
11. MligTC455_20201 1626 33.88 Mlig455_025333

Neo: -

Age: logFC(26M/2M)=-0.331

 TRPA1 2.616 - 0.769 - - 0.963 0.884 Mlig455_025333 {REF} {Length: 5343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=283.4]; Ankyrin repeat [PF00023.32, score=234.0]; Ankyrin repeats (many copies) [PF13637.8, score=227.4]; Ankyrin repeat [PF13606.8, score=217.2]; Ankyrin repeats (many copies) [PF13857.8, score=212.6]; Ion transport protein [PF00520.33, score=53.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=368, Expect=5e-107]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=363, Expect=2e-105]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=325, Expect=8e-92]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=2e-150]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [RH, Score=754, Expect=0.0]} {RNA1509_20092} {RNA1310_1173, RNA1509_20092} {RNA1509_20092, RNA815_336}
12. MligTC455_37308 1663 34.65 Mlig455_040453

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.651

 ARRDC1 2.585 - - 0.760 - 0.870 0.955 Mlig455_040453 {REF} {Length: 2316} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.2]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=63.8]} {Human: ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=80.5, Expect=1e-15]; ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=78.6, Expect=7e-15]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=73.6, Expect=2e-13]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=90.9, Expect=1e-19]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.1, Expect=5e-11]} {RNA1509_2401, RNA1509_53571} {RNA1310_27725, RNA1509_53571} {RNA1509_53571, RNA815_11006.1}
13. MligTC455_40024 3395 70.74 Mlig455_058212

Neo: -

Age: logFC(26M/2M)=-0.531

 ODF3 2.58 - 0.773 - - 0.965 0.842 Mlig455_058212 {REF} {Length: 1436} {TRANSSPLICED} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=65.8]} {Human: ENSG00000177947, ODF3, outer dense fiber of sperm tails 3, [RH, Score=179, Expect=2e-55]; ENSG00000177989, ODF3B, outer dense fiber of sperm tails 3B, [RH, Score=174, Expect=3e-53]} {Mouse: ENSMUSG00000025482, Odf3, outer dense fiber of sperm tails 3, [Score=172, Expect=1e-52]} {Dmel: FBgn0032010, CG8086, [RH, Score=119, Expect=3e-32]} {Smed: dd_Smed_v6_2658_0_1, dd_Smed_v6_2658_0_1, [RH, Score=322, Expect=3e-112]} {RNA1509_14103, RNA1509_4352} {RNA1310_23191, RNA1509_14103, RNA1509_4352} {RNA1509_14103, RNA1509_4352, RNA815_9849}
14. MligTC455_17580 2178 45.37 Mlig455_048028

Neo: -

Age: Down-Up-Up

 2.556 - 0.756 - - 0.848 0.952 Mlig455_048028 {REF} {Length: 5222} {RNA1509_12558, RNA1509_43882} {RNA1310_10969, RNA1509_43882} {RNA1509_43882, RNA815_3485.1}
15. MligTC455_25220 5921 123.36 Mlig455_036735

Neo: -

Age: -

 NME8 2.547 - 0.780 - - 0.814 0.953 Mlig455_036735 {REF} {Length: 2994} {Pfam: Nucleoside diphosphate kinase [PF00334.21, score=360.7]; Thioredoxin [PF00085.22, score=40.7]} {Human: ENSG00000086288, NME8, NME/NM23 family member 8, [RH, Score=331, Expect=1e-102]} {Mouse: ENSMUSG00000041138, Nme8, NME/NM23 family member 8, [RH, Score=310, Expect=5e-95]} {Dmel: FBgn0030359, CG18130, [RH, Score=97.1, Expect=2e-20]} {Celegans: WBGene00009119, ndk-1, Nucleoside diphosphate kinase, [Score=77.0, Expect=3e-16]} {Smed: dd_Smed_v6_8401_0_1, dd_Smed_v6_8401_0_1, [RH, Score=662, Expect=0.0]} {RNA1509_1203} {RNA1310_11078.1} {RNA815_3861}
16. MligTC455_47441 543 11.32 Mlig455_045866

Neo: -

Age: -

 2.545 - - 0.820 - 0.754 0.971 Mlig455_045866 {REF} {Length: 2993} {TRANSSPLICED} {Smed: dd_Smed_v6_11834_0_1, dd_Smed_v6_11834_0_1, [RH, Score=173, Expect=4e-47]} {RNA1509_34658, RNA1509_4754} {RNA1310_5693.1, RNA1509_34658, RNA1509_4754} {RNA1509_34658, RNA1509_4754, RNA815_2001}
17. MligTC455_53683 2280 47.51 Mlig455_008125, Mlig455_008133

Neo: -

Age: -

 ERICH6 2.519 - 0.765 - - 0.956 0.798

Mlig455_008125 {REF} {Length: 2384} {Pfam: FAM194 protein [PF14977.8, score=172.8]; Protein of unknown function (DUF429) [PF04250.15, score=20.3]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [Score=159, Expect=2e-41]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=114, Expect=7e-26]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=229, Expect=3e-66]} {RNA1509_13316} {RNA1310_9580.2} {RNA815_3023.1}

Mlig455_008133 {REF} {Length: 2411} {Pfam: FAM194 protein [PF14977.8, score=172.2]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [RH, Score=162, Expect=2e-42]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=230, Expect=1e-66]} {RNA1509_15088} {RNA1310_8374} {RNA815_3023.1}
18. MligTC455_54147 2046 42.63 Mlig455_062289

Neo: -

Age: Down-Up-Down

 DRC7 2.514 - 0.839 - 0.723 0.952 - Mlig455_062289 {REF} {Length: 3093} {Human: ENSG00000159625, DRC7, dynein regulatory complex subunit 7, [Score=642, Expect=0.0]} {Mouse: ENSMUSG00000031786, Drc7, dynein regulatory complex subunit 7, [Score=629, Expect=0.0]} {Dmel: FBgn0083946, lobo, lost boys, [Score=226, Expect=1e-61]} {Smed: dd_Smed_v6_12588_0_1, dd_Smed_v6_12588_0_1, [Score=588, Expect=0.0]} {RNA1509_1230} {RNA1310_4483} {RNA815_1294}
19. MligTC455_43683 520 10.83 Mlig455_029440

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.407

 2.506 - 0.733 - - 0.808 0.965 Mlig455_029440 {REF} {Length: 1842} {RNA1509_21217} {RNA1310_16933.1, RNA1509_21217} {RNA1509_21217, RNA815_7959}
20. MligTC455_24519 1035 21.55 Mlig455_026505

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.364/0.03756

 DNAH10 2.505 0.813 - - - 0.742 0.950 Mlig455_026505 {REF} {Length: 14733} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=521.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=390.5]; P-loop containing dynein motor region D4 [PF12780.9, score=341.0]; Dynein heavy chain C-terminal domain [PF18199.3, score=306.8]; ATP-binding dynein motor region [PF12781.9, score=282.5]; P-loop containing dynein motor region [PF12775.9, score=264.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=214.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=174.9]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=142.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=92.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=81.8]; AAA+ lid domain [PF17857.3, score=63.2]; AAA domain [PF13401.8, score=44.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=34.7]; AAA ATPase domain [PF13191.8, score=31.6]; AAA domain [PF13238.8, score=24.7]; MoxR domain in the MoxR-vWA-beta-propeller ternary systems [PF20030.1, score=21.4]; Sigma-54 interaction domain [PF00158.28, score=21.3]} {Human: ENSG00000281935, DNAH10, dynein axonemal heavy chain 10, [RH, Score=4662, Expect=0.0]} {Mouse: ENSMUSG00000038011, Dnah10, dynein, axonemal, heavy chain 10, [Score=4676, Expect=0.0]} {Dmel: FBgn0013813, Dhc98D, Dynein heavy chain at 89D, [RH, Score=3860, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1408, Expect=0.0]} {Smed: dd_Smed_v6_5169_0_1, dd_Smed_v6_5169_0_1, [RH, Score=4698, Expect=0.0]} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1310_40.1, RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395, RNA815_20}
21. MligTC455_51626 987 20.57 Mlig455_013225, Mlig455_013252, Mlig455_013320

Neo: -

Age: logFC(26M/2M)=-0.416

 NRG2 2.475 - - 0.711 - 0.809 0.955

Mlig455_013225 {REF} {Length: 3859} {Pfam: Immunoglobulin domain [PF13927.8, score=39.3]; Immunoglobulin I-set domain [PF07679.18, score=32.1]; Immunoglobulin domain [PF00047.27, score=29.5]; Immunoglobulin domain [PF13895.8, score=27.4]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=99.0, Expect=8e-21]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=93.2, Expect=7e-20]} {Dmel: FBgn0003984, vn, vein, [Score=65.9, Expect=6e-11]} {RNA1509_20317} {RNA1310_6062.1} {RNA815_3326.1}

Mlig455_013252 {REF} {Length: 3213} {Pfam: Immunoglobulin domain [PF13927.8, score=38.7]; Immunoglobulin I-set domain [PF07679.18, score=31.7]; Immunoglobulin domain [PF00047.27, score=29.2]; Immunoglobulin domain [PF13895.8, score=27.3]} {Human: ENSG00000158458, NRG2, neuregulin 2, [Score=98.2, Expect=2e-20]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [Score=92.4, Expect=6e-19]} {Dmel: FBgn0003984, vn, vein, [Score=65.1, Expect=1e-10]} {RNA1509_20317} {RNA1310_18314.1} {RNA815_3326.1}

Mlig455_013320 {REF} {Length: 4084} {Pfam: Immunoglobulin domain [PF13927.8, score=38.9]; Immunoglobulin I-set domain [PF07679.18, score=31.8]; Immunoglobulin domain [PF00047.27, score=29.3]; Immunoglobulin domain [PF13895.8, score=27.4]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=99.8, Expect=5e-21]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=93.6, Expect=6e-20]} {Dmel: FBgn0003984, vn, vein, [Score=65.9, Expect=7e-11]} {RNA1509_20317} {RNA1310_6062.1, RNA1509_20317} {RNA1509_20317, RNA815_3326.1}
22. MligTC455_41103 642 13.38 Mlig455_045043, Mlig455_045057

Neo: -

Age: logFC(26M/2M)=-0.438

 NEK11 1.925 - - - - 0.959 0.966

Mlig455_045043 {REF} {Length: 4762} {Pfam: Protein kinase domain [PF00069.27, score=182.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.0]; Ankyrin repeats (3 copies) [PF12796.9, score=71.5]; Ankyrin repeats (many copies) [PF13637.8, score=61.5]; Ankyrin repeats (many copies) [PF13857.8, score=50.6]; Ankyrin repeat [PF00023.32, score=42.2]; Ankyrin repeat [PF13606.8, score=40.6]; Kinase-like [PF14531.8, score=38.6]} {Human: ENSG00000114670, NEK11, NIMA related kinase 11, [Score=179, Expect=6e-49]; ENSG00000136098, NEK3, NIMA related kinase 3, [Score=173, Expect=2e-46]} {Mouse: ENSMUSG00000035032, Nek11, NIMA (never in mitosis gene a)-related expressed kinase 11, [Score=169, Expect=1e-44]; ENSMUSG00000031478, Nek3, NIMA (never in mitosis gene a)-related expressed kinase 3, [Score=164, Expect=2e-43]} {Dmel: FBgn0029970, Nek2, [Score=120, Expect=5e-28]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=120, Expect=4e-30]} {Smed: dd_Smed_v6_9098_0_1, dd_Smed_v6_9098_0_1, [Score=175, Expect=4e-47]} {RNA1509_16354} {RNA1310_7781.1} {RNA815_3814.1}

Mlig455_045057 {REF} {Length: 5140} {Pfam: Protein kinase domain [PF00069.27, score=182.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=134.4]; Ankyrin repeats (3 copies) [PF12796.9, score=68.5]; Ankyrin repeats (many copies) [PF13637.8, score=56.3]; Ankyrin repeats (many copies) [PF13857.8, score=45.7]; Ankyrin repeat [PF13606.8, score=41.0]; Ankyrin repeat [PF00023.32, score=40.2]; Kinase-like [PF14531.8, score=38.6]} {Human: ENSG00000114670, NEK11, NIMA related kinase 11, [Score=179, Expect=4e-49]; ENSG00000136098, NEK3, NIMA related kinase 3, [Score=174, Expect=1e-46]} {Mouse: ENSMUSG00000035032, Nek11, NIMA (never in mitosis gene a)-related expressed kinase 11, [Score=170, Expect=7e-45]; ENSMUSG00000031478, Nek3, NIMA (never in mitosis gene a)-related expressed kinase 3, [Score=165, Expect=8e-44]} {Dmel: FBgn0029970, Nek2, [Score=120, Expect=6e-28]} {Celegans: WBGene00008956, nekl-3, Serine/threonine-protein kinase nekl-3, [Score=121, Expect=3e-30]} {Smed: dd_Smed_v6_9098_0_1, dd_Smed_v6_9098_0_1, [Score=175, Expect=4e-47]} {RNA1509_16354, RNA1509_24492} {RNA1310_7781.2, RNA1509_16354, RNA1509_24492} {RNA1509_16354, RNA1509_24492, RNA815_3814.1}
23. MligTC455_43081 1884 39.25 Mlig455_016157

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.582

 SPATA18 1.896 - - 0.951 - 0.945 - Mlig455_016157 {REF} {Length: 2912} {Pfam: Mitochondria-eating protein [PF16026.7, score=158.7]; Survival motor neuron protein (SMN) [PF06003.14, score=22.7]; NUP57/Nup54 C-terminal domain [PF18570.3, score=20.4]} {Human: ENSG00000163071, SPATA18, spermatogenesis associated 18, [RH, Score=284, Expect=7e-89]} {Mouse: ENSMUSG00000029155, Spata18, spermatogenesis associated 18, [RH, Score=274, Expect=5e-85]} {Smed: dd_Smed_v6_6321_0_1, dd_Smed_v6_6321_0_1, [RH, Score=422, Expect=2e-143]} {RNA1509_37816, RNA1509_39898, RNA1509_46068, RNA1509_5610, RNA1509_60121} {RNA1310_6400, RNA1509_37816, RNA1509_39898, RNA1509_46068, RNA1509_5610, RNA1509_60121} {RNA1509_37816, RNA1509_39898, RNA1509_46068, RNA1509_5610, RNA1509_60121, RNA815_12342}
24. MligTC455_46887 1771 36.89 Mlig455_023150

Neo: -

Age: logFC(26M/2M)=-0.580

 SLC25A14 1.886 - - - 0.922 - 0.964 Mlig455_023150 {REF} {Length: 2121} {Pfam: Mitochondrial carrier protein [PF00153.29, score=221.0]} {Human: ENSG00000102078, SLC25A14, solute carrier family 25 member 14, [RH, Score=287, Expect=1e-95]; ENSG00000174032, SLC25A30, solute carrier family 25 member 30, [RH, Score=281, Expect=2e-93]} {Mouse: ENSMUSG00000031105, Slc25a14, solute carrier family 25 (mitochondrial carrier, brain), member 14, [RH, Score=284, Expect=2e-94]; ENSMUSG00000022003, Slc25a30, solute carrier family 25, member 30, [RH, Score=281, Expect=9e-94]} {Dmel: FBgn0036199, Bmcp, [RH, Score=259, Expect=8e-85]} {Celegans: WBGene00015186, misc-1, MItochondrial Solute Carrier, [Score=166, Expect=1e-48]} {Smed: dd_Smed_v6_8945_0_8, dd_Smed_v6_8945_0_8, [RH, Score=250, Expect=1e-81]} {RNA1509_12259} {RNA1310_31014} {RNA815_1562.1}
25. MligTC455_47476 7650 159.38 Mlig455_011139

Neo: -

Age: logFC(26M/2M)=-0.342

 RSPH1 1.854 - - - - 0.955 0.899 Mlig455_011139 {REF} {Length: 1427} {Pfam: MORN repeat [PF02493.22, score=123.5]} {Human: ENSG00000160188, RSPH1, radial spoke head component 1, [RH, Score=256, Expect=6e-84]} {Mouse: ENSMUSG00000024033, Rsph1, radial spoke head 1 homolog (Chlamydomonas), [RH, Score=266, Expect=8e-88]} {Dmel: FBgn0032478, CG5458, [RH, Score=149, Expect=6e-42]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=59.3, Expect=1e-09]} {Smed: dd_Smed_v6_3321_0_1, dd_Smed_v6_3321_0_1, [RH, Score=306, Expect=6e-104]} {RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1310_22398, RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1509_10402, RNA1509_5779, RNA1509_6982, RNA815_10865}
26. MligTC455_43002 147 3.07 Mlig455_004304

Neo: -

Age: Up-Down-Down

 GLUD1 1.852 - - - - 0.900 0.952 Mlig455_004304 {REF} {Length: 2088} {Pfam: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=134.8]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=288, Expect=8e-94]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=285, Expect=5e-93]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=288, Expect=5e-94]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=288, Expect=2e-96]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=240, Expect=4e-76]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=277, Expect=1e-90]} {RNA1509_18938, RNA1509_30743} {RNA1310_2661.2, RNA1509_18938} {RNA1509_18938, RNA815_713.2}
27. MligTC455_29049 441 9.18 Mlig455_042244

Neo: -

Age: -

Region-enriched R2: 4.677/0.00000
Region-enriched R3: 2.595/0.01002

 RASGRF1 1.851 - - - 0.969 0.882 - Mlig455_042244 {REF} {Length: 6465} {Pfam: RasGEF domain [PF00617.21, score=193.2]; RhoGEF domain [PF00621.22, score=119.3]; PH domain [PF00169.31, score=86.7]; RasGEF N-terminal motif [PF00618.22, score=68.4]; Pleckstrin homology domain [PF15413.8, score=22.6]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=763, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=739, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=763, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=164, Expect=3e-40]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=118, Expect=3e-26]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1137, Expect=0.0]} {RNA1509_15697} {RNA1310_2543.1} {RNA815_8228.1}
28. MligTC455_18720 595 12.4 Mlig455_041810

Neo: -

Age: logFC(26M/2M)=-0.320

 ANKUB1 1.847 - - - - 0.886 0.961 Mlig455_041810 {REF} {Length: 2454} {Pfam: Ubiquitin family [PF00240.25, score=36.0]} {Human: ENSG00000206199, ANKUB1, ankyrin repeat and ubiquitin domain containing 1, [RH, Score=258, Expect=8e-78]} {Mouse: ENSMUSG00000074591, Ankub1, ankrin repeat and ubiquitin domain containing 1, [RH, Score=258, Expect=5e-78]} {Smed: dd_Smed_v6_9027_0_1, dd_Smed_v6_9027_0_1, [RH, Score=508, Expect=2e-173]} {RNA1509_23349, RNA1509_30870, RNA1509_7686} {RNA1310_10366.1, RNA1509_23349, RNA1509_30870, RNA1509_7686} {RNA1509_23349, RNA1509_30870, RNA1509_7686, RNA815_3711.1}
29. MligTC455_16051 3672 76.49 Mlig455_051486

Neo: -

Age: Down-Down-Up

 NUDT9 1.843 - 0.893 - - 0.950 - Mlig455_051486 {REF} {Length: 1822} {TRANSSPLICED} {Pfam: NUDIX domain [PF00293.30, score=22.9]} {Human: ENSG00000170502, NUDT9, nudix hydrolase 9, [RH, Score=278, Expect=8e-92]} {Mouse: ENSMUSG00000029310, Nudt9, nudix (nucleoside diphosphate linked moiety X)-type motif 9, [RH, Score=281, Expect=4e-93]} {Dmel: FBgn0036648, CG4098, [RH, Score=258, Expect=1e-84]} {Celegans: WBGene00003583, ndx-6, Putative nudix hydrolase 6, [RH, Score=214, Expect=2e-68]} {Smed: dd_Smed_v6_1143_0_1, dd_Smed_v6_1143_0_1, [RH, Score=293, Expect=1e-98]} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_4802, RNA1509_51897} {RNA1310_32536, RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897, RNA815_11473.1}
30. MligTC455_03314 1048 21.84 Mlig455_065746

Neo: -

Age: -

 1.837 - - 0.866 - 0.971 - Mlig455_065746 {REF} {Length: 1336} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=23.9]} {RNA1509_5447} {RNA1310_26690.1} {RNA815_11584}
31. MligTC455_49257 739 15.4 Mlig455_033298

Neo: -

Age: -

 MFHAS1 1.82 - - 0.854 - - 0.966 Mlig455_033298 {REF} {Length: 1564} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=64.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=44.5]; Leucine-rich repeat [PF14580.8, score=29.1]} {Human: ENSG00000147324, MFHAS1, malignant fibrous histiocytoma amplified sequence 1, [Score=102, Expect=4e-23]; ENSG00000285022, AC270282.1, malignant fibrous histiocytoma amplified sequence 1, [Score=102, Expect=4e-23]} {Mouse: ENSMUSG00000070056, Mfhas1, malignant fibrous histiocytoma amplified sequence 1, [Score=94.7, Expect=1e-20]} {Dmel: FBgn0263289, scrib, scribbled, [Score=87.8, Expect=2e-18]} {Celegans: WBGene00004929, soc-2, Leucine-rich repeat protein soc-2, [Score=85.1, Expect=8e-18]} {Smed: dd_Smed_v6_11443_0_1, dd_Smed_v6_11443_0_1, [RH, Score=102, Expect=7e-25]} {RNA1509_32286, RNA1509_43570} {RNA1310_22536.1, RNA1509_32286, RNA1509_43570} {RNA1509_32286, RNA1509_43570, RNA815_11933}
32. MligTC455_43338 3043 63.4 Mlig455_057398, Mlig455_059559

Neo: -

Age: logFC(26M/2M)=-0.259

Region-enriched R2: 1.086/0.00779

 CYB5D1 1.818 - - - - 0.855 0.963

Mlig455_057398 {REF} {Length: 1138} {Pfam: Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.8]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [Score=215, Expect=1e-70]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [Score=223, Expect=7e-74]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [Score=221, Expect=3e-73]} {RNA1509_11346} {RNA1310_26198} {RNA815_11579}

Mlig455_059559 {REF} {Length: 1306} {Pfam: Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=35.0]; Ubiquitin-2 like Rad60 SUMO-like [PF11976.10, score=25.5]} {Human: ENSG00000182224, CYB5D1, cytochrome b5 domain containing 1, [RH, Score=260, Expect=6e-88]} {Mouse: ENSMUSG00000044795, Cyb5d1, cytochrome b5 domain containing 1, [RH, Score=263, Expect=2e-89]; ENSMUSG00000032889, Gm6685, predicted pseudogene 6685, [RH, Score=260, Expect=3e-88]} {RNA1509_5289} {RNA1310_26198, RNA1509_5289} {RNA1509_5289, RNA815_11579}
33. MligTC455_46795 785 16.35 Mlig455_000535

Neo: -

Age: logFC(26M/2M)=-0.364

Region-enriched R2: 1.672/0.01916

 HTR1B 1.809 - 0.848 - 0.961 - - Mlig455_000535 {REF} {Length: 4573} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=255.2]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=53.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=23.4]; Family of unknown function (DUF5684) [PF18936.2, score=19.6]} {Human: ENSG00000135312, HTR1B, 5-hydroxytryptamine receptor 1B, [RH, Score=243, Expect=3e-75]} {Mouse: ENSMUSG00000021721, Htr1a, 5-hydroxytryptamine (serotonin) receptor 1A, [Score=251, Expect=3e-78]} {Dmel: FBgn0004573, 5-HT7, 5-hydroxytryptamine (serotonin) receptor 7, [RH, Score=276, Expect=2e-86]} {Celegans: WBGene00004780, ser-7, SERotonin/octopamine receptor family, [RH, Score=221, Expect=1e-66]} {Smed: dd_Smed_v6_5341_0_1, dd_Smed_v6_5341_0_1, [RH, Score=412, Expect=2e-140]} {RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1310_3896.1, RNA1509_11749, RNA1509_13593, RNA1509_37815} {RNA1509_11749, RNA1509_13593, RNA1509_37815, RNA815_3010}
34. MligTC455_24735 1026 21.38 Mlig455_003136

Neo: -

Age: logFC(26M/2M)=-0.296

 VWA3B 1.804 - - - - 0.837 0.967 Mlig455_003136 {REF} {Length: 2787} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=231.3]; DNA repair protein Crb2 Tudor domain [PF18115.3, score=42.4]; SGF29 tudor-like domain [PF07039.13, score=39.7]; Jumonji domain-containing protein 2A Tudor domain [PF18104.3, score=33.4]; SPX domain [PF03105.21, score=20.6]} {Human: ENSG00000168658, VWA3B, von Willebrand factor A domain containing 3B, [RH, Score=79.7, Expect=4e-15]} {RNA1509_5206} {RNA1310_5951.1, RNA1509_5206} {RNA1509_5206, RNA815_1760.1}
35. MligTC455_52579 638 13.29 Mlig455_000801

Neo: -

Age: -

 CAPN11 1.804 - - - - 0.830 0.974 Mlig455_000801 {REF} {Length: 2780} {Pfam: Calpain family cysteine protease [PF00648.23, score=316.9]; Calpain large subunit, domain III [PF01067.24, score=84.3]} {Human: ENSG00000137225, CAPN11, calpain 11, [Score=283, Expect=5e-87]; ENSG00000162909, CAPN2, calpain 2, [Score=278, Expect=2e-85]; ENSG00000203697, CAPN8, calpain 8, [Score=275, Expect=5e-84]; ENSG00000014216, CAPN1, calpain 1, [Score=273, Expect=3e-83]; ENSG00000135773, CAPN9, calpain 9, [Score=272, Expect=4e-83]; ENSG00000092529, CAPN3, calpain 3, [Score=271, Expect=2e-82]} {Mouse: ENSMUSG00000026509, Capn2, calpain 2, [Score=275, Expect=4e-84]; ENSMUSG00000024942, Capn1, calpain 1, [Score=273, Expect=2e-83]; ENSMUSG00000038599, Capn8, calpain 8, [Score=273, Expect=1e-83]; ENSMUSG00000058626, Capn11, calpain 11, [Score=271, Expect=1e-82]; ENSMUSG00000079110, Capn3, calpain 3, [Score=270, Expect=2e-82]; ENSMUSG00000035547, Capn5, calpain 5, [Score=269, Expect=1e-82]; ENSMUSG00000031981, Capn9, calpain 9, [Score=265, Expect=2e-80]} {Dmel: FBgn0012051, CalpA, Calpain-A, [Score=323, Expect=3e-104]} {Celegans: WBGene00000546, clp-6, CaLPain family, [Score=280, Expect=3e-87]} {Smed: dd_Smed_v6_1752_0_4, dd_Smed_v6_1752_0_4, [Score=302, Expect=2e-94]} {RNA1509_24213, RNA1509_39830} {RNA1310_15231, RNA1509_24213, RNA1509_39830} {RNA1509_24213, RNA1509_39830, RNA815_6675}
36. MligTC455_30353 28486 593.46 Mlig455_048234

Neo: -

Age: Up-Down-Up

 TUBB4B 1.792 - 0.828 - - 0.964 - Mlig455_048234 {REF} {Length: 2052} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=232.0]; Tubulin C-terminal domain [PF03953.19, score=144.9]; Misato Segment II tubulin-like domain [PF10644.11, score=24.4]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [RH, Score=922, Expect=0.0]; ENSG00000137285, TUBB2B, tubulin beta 2B class IIb, [RH, Score=910, Expect=0.0]; ENSG00000104833, TUBB4A, tubulin beta 4A class IVa, [RH, Score=908, Expect=0.0]; ENSG00000227739, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000196230, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000232421, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000224156, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000235067, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000183311, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000229684, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000232575, TUBB, tubulin beta class I, [RH, Score=905, Expect=0.0]; ENSG00000137267, TUBB2A, tubulin beta 2A class IIa, [RH, Score=905, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [RH, Score=922, Expect=0.0]; ENSMUSG00000045136, Tubb2b, tubulin, beta 2B class IIB, [RH, Score=910, Expect=0.0]; ENSMUSG00000062591, Tubb4a, tubulin, beta 4A class IVA, [RH, Score=908, Expect=0.0]; ENSMUSG00000058672, Tubb2a, tubulin, beta 2A class IIA, [RH, Score=905, Expect=0.0]; ENSMUSG00000001525, Tubb5, tubulin, beta 5 class I, [RH, Score=905, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [RH, Score=863, Expect=0.0]} {Celegans: WBGene00006538, tbb-4, Tubulin beta-4 chain, [RH, Score=860, Expect=0.0]} {Smed: dd_Smed_v6_83_0_3, dd_Smed_v6_83_0_3, [RH, Score=919, Expect=0.0]} {RNA1509_1311, RNA1509_13882, RNA1509_1520, RNA1509_18329, RNA1509_2072, RNA1509_3253, RNA1509_4483, RNA1509_51206, RNA1509_7458, RNA1509_7539} {RNA1310_15130.1, RNA1509_1311, RNA1509_13882, RNA1509_1520, RNA1509_18329, RNA1509_2072, RNA1509_3253, RNA1509_4483, RNA1509_51206, RNA1509_7458, RNA1509_7539} {RNA1509_1311, RNA1509_13882, RNA1509_1520, RNA1509_18329, RNA1509_2072, RNA1509_3253, RNA1509_4483, RNA1509_51206, RNA1509_7458, RNA1509_7539, RNA815_1610.2}
37. MligTC455_27667 53550 1115.62 Mlig455_018381, Mlig455_069522

Neo: -

Age: logFC(26M/2M)=0.722

 TUBA1A 1.788 - 0.806 - - 0.982 -

Mlig455_018381 {REF} {Length: 2129} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=226.5]; Tubulin C-terminal domain [PF03953.19, score=173.4]; PIF1-like helicase [PF05970.16, score=94.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=92.2]; AAA domain [PF13604.8, score=59.8]; AAA domain [PF13245.8, score=35.3]; Tubulin domain [PF14881.8, score=18.5]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=946, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=943, Expect=0.0]; ENSG00000075886, TUBA3D, tubulin alpha 3d, [RH, Score=936, Expect=0.0]; ENSG00000198033, TUBA3C, tubulin alpha 3c, [RH, Score=936, Expect=0.0]; ENSG00000152086, TUBA3E, tubulin alpha 3e, [RH, Score=919, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=946, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=943, Expect=0.0]; ENSMUSG00000067338, Tuba3b, tubulin, alpha 3B, [RH, Score=936, Expect=0.0]; ENSMUSG00000067702, Tuba3a, tubulin, alpha 3A, [RH, Score=936, Expect=0.0]; ENSMUSG00000043091, Tuba1c, tubulin, alpha 1C, [RH, Score=928, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=932, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=862, Expect=0.0]} {Smed: dd_Smed_v6_10947_0_2, dd_Smed_v6_10947_0_2, [RH, Score=943, Expect=0.0]} {RNA1509_1730, RNA1509_3160, RNA1509_3273, RNA1509_38752, RNA1509_41246, RNA1509_55904, RNA1509_9718} {RNA1310_10339.1, RNA1509_1730, RNA1509_3160, RNA1509_3273, RNA1509_38752, RNA1509_41246, RNA1509_55904, RNA1509_9718} {RNA1509_1730, RNA1509_3160, RNA1509_3273, RNA1509_38752, RNA1509_41246, RNA1509_55904, RNA1509_9718, RNA815_1715.1}

Mlig455_069522 {REF} {Length: 5873} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=226.5]; Tubulin C-terminal domain [PF03953.19, score=173.4]; PIF1-like helicase [PF05970.16, score=94.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=92.2]; AAA domain [PF13604.8, score=59.8]; AAA domain [PF13245.8, score=35.3]; Tubulin domain [PF14881.8, score=18.5]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=946, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=943, Expect=0.0]; ENSG00000075886, TUBA3D, tubulin alpha 3d, [RH, Score=936, Expect=0.0]; ENSG00000198033, TUBA3C, tubulin alpha 3c, [RH, Score=936, Expect=0.0]; ENSG00000152086, TUBA3E, tubulin alpha 3e, [RH, Score=919, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=946, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=943, Expect=0.0]; ENSMUSG00000067338, Tuba3b, tubulin, alpha 3B, [RH, Score=936, Expect=0.0]; ENSMUSG00000067702, Tuba3a, tubulin, alpha 3A, [RH, Score=936, Expect=0.0]; ENSMUSG00000043091, Tuba1c, tubulin, alpha 1C, [RH, Score=928, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=932, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=862, Expect=0.0]} {Smed: dd_Smed_v6_10947_0_2, dd_Smed_v6_10947_0_2, [RH, Score=943, Expect=0.0]} {RNA1509_2607} {RNA1310_72.1} {RNA815_1193}
38. MligTC455_30352 28839 600.8 Mlig455_048232

Neo: -

Age: -

 1.788 - 0.828 - - 0.960 - Mlig455_048232 {REF} {Length: 862} {RNA1509_35539, RNA1509_53157} {RNA1310_17208, RNA1509_35539} {RNA1509_35539, RNA815_4202.1}
39. MligTC455_39661 1164 24.25 Mlig455_005995

Neo: -

Age: -

 1.777 - - - 0.822 - 0.955 Mlig455_005995 {REF} {Length: 2256} {Pfam: Centromere protein B dimerisation domain [PF09026.12, score=23.1]} {RNA1509_10323} {RNA1310_17058, RNA1509_10323} {RNA1509_10323, RNA815_6315.1}
40. MligTC455_09153 784 16.32 Mlig455_026817

Neo: -

Age: -

 1.775 0.818 - - - 0.957 - Mlig455_026817 {REF} {Length: 1131} {TRANSSPLICED} {RNA1509_40542} {RNA1310_5275.2} {RNA815_1594}
41. MligTC455_49394 1184 24.68 Mlig455_041577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.255/0.02823

 1.766 - - - - 0.788 0.978 Mlig455_041577 {REF} {Length: 928} {Pfam: Normal lung function maintenance, Low in Lung Cancer 1 protein [PF14945.8, score=24.7]} {Smed: dd_Smed_v6_6024_0_1, dd_Smed_v6_6024_0_1, [Score=97.8, Expect=1e-26]} {RNA1509_17780, RNA1509_38038} {RNA1310_47454, RNA1509_17780, RNA1509_38038} {RNA1509_17780, RNA1509_38038, RNA815_24792.1}
42. MligTC455_49180 501 10.44 Mlig455_030419

Neo: -

Age: logFC(26M/2M)=-0.221

 GRIK1 1.757 - - - - 0.807 0.950 Mlig455_030419 {REF} {Length: 3001} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=21.2]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=78.2, Expect=4e-14]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=75.5, Expect=3e-13]} {Mouse: ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=76.3, Expect=1e-13]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=75.5, Expect=2e-13]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=68.2, Expect=2e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=73.2, Expect=4e-13]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
43. MligTC455_44145 1616 33.67 Mlig455_013447

Neo: -

Age: -

 1.752 - - - - 0.794 0.958 Mlig455_013447 {REF} {Length: 841} {RNA1509_20243} {RNA1310_1688.1} {RNA815_1415.1}
44. MligTC455_50505 454 9.46 Mlig455_050904

Neo: -

Age: Down-Up-Up

 1.751 - - - - 0.772 0.979 Mlig455_050904 {REF} {Length: 1806} {RNA1509_31617} {RNA1310_16888, RNA1509_31617} {RNA1509_31617, RNA815_20985}
45. MligTC455_44898 1324 27.58 Mlig455_052276, Mlig455_052367

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.296

 SPATA48 1.742 - - 0.791 - - 0.951

Mlig455_052276 {REF} {Length: 2638} {Pfam: Spermatogenesis-associated protein 48 [PF15073.8, score=93.3]} {Human: ENSG00000164500, SPATA48, spermatogenesis associated 48, [RH, Score=70.1, Expect=2e-12]} {Mouse: ENSMUSG00000020191, Spata48, spermatogenesis associated 48, [RH, Score=63.2, Expect=2e-10]} {Smed: dd_Smed_v6_3031_1_1, dd_Smed_v6_3031_1_1, [RH, Score=170, Expect=1e-48]} {RNA1509_6429} {RNA1310_9625} {RNA815_10679.1}

Mlig455_052367 {REF} {Length: 2936} {Pfam: Spermatogenesis-associated protein 48 [PF15073.8, score=93.3]} {Human: ENSG00000164500, SPATA48, spermatogenesis associated 48, [RH, Score=70.1, Expect=2e-12]} {Mouse: ENSMUSG00000020191, Spata48, spermatogenesis associated 48, [RH, Score=63.2, Expect=2e-10]} {Smed: dd_Smed_v6_3031_1_1, dd_Smed_v6_3031_1_1, [RH, Score=170, Expect=1e-48]} {RNA1509_22834, RNA1509_30893, RNA1509_6429} {RNA1310_9625, RNA1509_22834, RNA1509_30893, RNA1509_6429} {RNA1509_22834, RNA1509_30893, RNA1509_6429, RNA815_10679.1}
46. MligTC455_52734 555 11.57 Mlig455_038511

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.535

Region-specific R2: 2.258

Region-enriched R2: 2.161/0.00016

 RBM12B 1.733 - - - - 0.762 0.971 Mlig455_038511 {REF} {Length: 3692} {Pfam: Otopetrin [PF03189.15, score=53.6]} {Human: ENSG00000183808, RBM12B, RNA binding motif protein 12B, [Score=63.5, Expect=2e-09]} {RNA1509_57555} {RNA1310_7630.2} {RNA815_2303}
47. MligTC455_35568 2158 44.97 Mlig455_021702

Neo: -

Age: logFC(26M/2M)=-0.363

 CFAP44 1.731 - - - - 0.959 0.772 Mlig455_021702 {REF} {Length: 6525} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=22.8]} {Human: ENSG00000206530, CFAP44, cilia and flagella associated protein 44, [RH, Score=1198, Expect=0.0]} {Mouse: ENSMUSG00000071550, Cfap44, cilia and flagella associated protein 44, [RH, Score=1139, Expect=0.0]} {Dmel: FBgn0083960, CG34124, [RH, Score=558, Expect=5e-165]} {Smed: dd_Smed_v6_8760_0_1, dd_Smed_v6_8760_0_1, [RH, Score=1665, Expect=0.0]} {RNA1509_22831} {RNA1310_539.1, RNA1509_22831} {RNA1509_22831, RNA815_87.1}
48. MligTC455_52303 382 7.96 Mlig455_009518

Neo: -

Age: -

Region-enriched R2: 1.953/0.01722

 FAM149B1 1.73 - - - - 0.759 0.971 Mlig455_009518 {REF} {Length: 3223} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF3719) [PF12516.10, score=23.9]} {Human: ENSG00000138286, FAM149B1, family with sequence similarity 149 member B1, [RH, Score=79.3, Expect=1e-14]} {Mouse: ENSMUSG00000070044, Fam149a, family with sequence similarity 149, member A, [Score=74.7, Expect=2e-13]} {Smed: dd_Smed_v6_13092_0_1, dd_Smed_v6_13092_0_1, [Score=98.2, Expect=5e-21]} {RNA1509_15304} {RNA1310_4854, RNA1509_15304} {RNA1509_15304, RNA815_5012.1}
49. MligTC455_24359 269 5.6 Mlig455_061470

Neo: -

Age: logFC(26M/2M)=-0.300

 1.729 - - - - 0.766 0.963 Mlig455_061470 {REF} {Length: 1541} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=44.6]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=189, Expect=6e-60]} {RNA1509_15325, RNA1509_47076} {RNA1310_24934.1, RNA1509_15325, RNA1509_47076} {RNA1509_15325, RNA1509_47076, RNA815_10915.1}
50. MligTC455_53681 335 6.99 Mlig455_064921

Neo: -

Age: -

Region-enriched R2: 6.469/0.00000

 1.727 - - - - 0.756 0.971 Mlig455_064921 {REF} {Length: 1504} {Pfam: PAN domain [PF00024.28, score=19.3]} {RNA1310_33258} {RNA815_17150}
51. MligTC455_52118 5757 119.94 Mlig455_069122

Neo: -

Age: logFC(26M/2M)=0.892

 CFAP58 1.702 - 0.747 - - 0.955 - Mlig455_069122 {REF} {Length: 3136} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=23.0]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=923, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=991, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=1e-40]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1103, Expect=0.0]} {RNA1509_282} {RNA1310_4570, RNA1509_282} {RNA1509_282, RNA815_1528}
52. MligTC455_27219 4029 83.93 Mlig455_007044

Neo: -

Age: logFC(26M/2M)=-0.389

 TEKT2 1.696 - - 0.731 - 0.965 - Mlig455_007044 {REF} {Length: 1859} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=375.3]} {Human: ENSG00000092850, TEKT2, tektin 2, [Score=380, Expect=2e-129]} {Mouse: ENSMUSG00000028845, Tekt2, tektin 2, [Score=349, Expect=1e-117]} {Dmel: FBgn0034816, CG3085, [Score=183, Expect=2e-53]} {Celegans: WBGene00019828, R02E12.4, [Score=72.8, Expect=1e-13]} {Smed: dd_Smed_v6_2339_0_1, dd_Smed_v6_2339_0_1, [Score=503, Expect=1e-178]} {RNA1509_1922} {RNA1310_13089.2} {RNA815_4479}
53. MligTC455_42154 1301 27.11 Mlig455_057280, Mlig455_059618

Neo: -

Age: logFC(26M/2M)=-0.356

Region-enriched R2: 1.850/0.00451
Region-enriched R3: 1.206/0.02005

 EFCAB5 1.691 - - 0.962 - 0.729 -

Mlig455_057280 {REF} {Length: 5873} {Pfam: GAF domain [PF01590.28, score=28.1]; EF hand [PF00036.34, score=21.8]; EF-hand domain [PF13405.8, score=20.6]} {Human: ENSG00000176927, EFCAB5, EF-hand calcium binding domain 5, [RH, Score=399, Expect=2e-115]} {Mouse: ENSMUSG00000050944, Efcab5, EF-hand calcium binding domain 5, [RH, Score=367, Expect=8e-105]} {Smed: dd_Smed_v6_8209_0_1, dd_Smed_v6_8209_0_1, [RH, Score=529, Expect=2e-164]} {RNA1509_1330} {RNA1310_1624} {RNA815_449}

Mlig455_059618 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: GAF domain [PF01590.28, score=28.2]; EF hand [PF00036.34, score=21.8]; EF-hand domain [PF13405.8, score=20.7]} {Human: ENSG00000176927, EFCAB5, EF-hand calcium binding domain 5, [RH, Score=400, Expect=6e-116]} {Mouse: ENSMUSG00000050944, Efcab5, EF-hand calcium binding domain 5, [RH, Score=368, Expect=2e-105]} {Smed: dd_Smed_v6_8209_0_1, dd_Smed_v6_8209_0_1, [RH, Score=528, Expect=4e-164]} {RNA1509_1330, RNA1509_26864} {RNA1310_1439, RNA1509_26864} {RNA1509_26864, RNA815_449}
54. MligTC455_35046 485 10.1 Mlig455_067666

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.340

Region-enriched R8: 2.605/0.02555
Region-enriched R2: 2.499/0.01493

 PDE2A 1.688 - - - - 0.718 0.970 Mlig455_067666 {REF} {Length: 5187} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=237.1]; GAF domain [PF01590.28, score=63.4]; GAF domain [PF13492.8, score=25.2]} {Human: ENSG00000186642, PDE2A, phosphodiesterase 2A, [RH, Score=718, Expect=0.0]} {Mouse: ENSMUSG00000030653, Gm45837, predicted gene 45837, [RH, Score=713, Expect=0.0]; ENSMUSG00000110195, Pde2a, phosphodiesterase 2A, cGMP-stimulated, [RH, Score=713, Expect=0.0]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [Score=325, Expect=2e-95]} {Celegans: WBGene00011146, pde-2, Probable 3',5'-cyclic phosphodiesterase pde-2, [RH, Score=334, Expect=7e-101]} {Smed: dd_Smed_v6_8589_0_2, dd_Smed_v6_8589_0_2, [RH, Score=817, Expect=0.0]} {RNA1509_5437} {RNA1310_2713.4} {RNA815_1901.1}
55. MligTC455_45062 1063 22.15 Mlig455_044267

Neo: -

Age: -

 1.684 - - 0.730 - 0.954 - Mlig455_044267 {REF} {Length: 1936} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=31.9]} {Smed: dd_Smed_v6_2982_0_2, dd_Smed_v6_2982_0_2, [Score=72.0, Expect=1e-14]} {RNA1509_23162, RNA1509_50902} {RNA1310_19283, RNA1509_23162, RNA1509_50902} {RNA1509_23162, RNA1509_50902, RNA815_7600.1}
56. MligTC455_49484 10996 229.08 Mlig455_045342

Neo: -

Age: logFC(26M/2M)=-0.289

Region-enriched R2: 1.032/0.00001

 PCCB 1.674 - - 0.707 - 0.967 - Mlig455_045342 {REF} {Length: 2338} {TRANSSPLICED} {Pfam: Carboxyl transferase domain [PF01039.24, score=621.7]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=25.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [RH, Score=789, Expect=0.0]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [RH, Score=785, Expect=0.0]} {Dmel: FBgn0042083, CG3267, [Score=235, Expect=6e-70]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [RH, Score=785, Expect=0.0]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [RH, Score=839, Expect=0.0]} {RNA1509_1631, RNA1509_328} {RNA1310_10357.1, RNA1509_1631} {RNA1509_1631, RNA815_3334.1}
57. MligTC455_40801 425 8.85 Mlig455_003100, Mlig455_062789

Neo: -

Age: logFC(26M/2M)=-0.250

Region-enriched R2: 3.506/0.00053
Region-enriched R3: 2.405/0.00633

 MDH1B 1.673 - 0.721 - - - 0.952

Mlig455_003100 {REF} {Length: 4802} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=53.0]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [Score=323, Expect=1e-102]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [Score=304, Expect=1e-95]} {Dmel: FBgn0262782, Mdh1, Malate dehydrogenase 1, [Score=107, Expect=3e-25]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=98.2, Expect=4e-22]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [Score=335, Expect=2e-106]} {RNA1509_47623, RNA1509_9622} {RNA1310_5189, RNA1509_47623} {RNA1509_47623, RNA815_3770}

Mlig455_062789 {REF} {Length: 2979} {Pfam: lactate/malate dehydrogenase, alpha/beta C-terminal domain [PF02866.20, score=52.9]} {Human: ENSG00000138400, MDH1B, malate dehydrogenase 1B, [Score=323, Expect=1e-102]} {Mouse: ENSMUSG00000025963, Mdh1b, malate dehydrogenase 1B, NAD (soluble), [Score=304, Expect=1e-95]} {Dmel: FBgn0262782, Mdh1, Malate dehydrogenase 1, [Score=105, Expect=2e-24]} {Celegans: WBGene00018491, mdh-1, Malate DeHydrogenase, [Score=97.8, Expect=5e-22]} {Smed: dd_Smed_v6_10200_0_1, dd_Smed_v6_10200_0_1, [RH, Score=337, Expect=1e-107]} {RNA1509_9622} {RNA1310_5189, RNA1509_9622} {RNA1509_9622, RNA815_3770}
58. MligTC455_09317 1638 34.12 Mlig455_061529

Neo: -

Age: Down-Down-Up

 1.664 - 0.701 - 0.963 - - Mlig455_061529 {REF} {Length: 2922} {RNA1509_44877} {RNA1310_25423.1, RNA1509_44877} {RNA1509_44877, RNA815_162}
59. MligTC455_18481 1416 29.5 Mlig455_061762

Neo: -

Age: Down-Down-Up

Region-enriched R2: 1.816/0.04103

 IFT88 1.66 - - - - 0.950 0.710 Mlig455_061762 {REF} {Length: 3149} {Pfam: Tetratricopeptide repeat [PF07719.19, score=111.4]; Tetratricopeptide repeat [PF00515.30, score=99.7]; Tetratricopeptide repeat [PF13424.8, score=98.0]; Tetratricopeptide repeat [PF13181.8, score=76.4]; Tetratricopeptide repeat [PF14559.8, score=73.3]; Tetratricopeptide repeat [PF13174.8, score=71.7]; Tetratricopeptide repeat [PF13432.8, score=71.0]; Tetratricopeptide repeat [PF13428.8, score=70.9]; Tetratricopeptide repeat [PF13176.8, score=61.5]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=56.3]; TPR repeat [PF13414.8, score=50.2]; Tetratricopeptide repeat [PF13371.8, score=40.4]; Tetratricopeptide repeat [PF13374.8, score=31.9]; Tetratricopeptide repeat-like domain [PF09976.11, score=28.6]; Tetratricopeptide repeat [PF13431.8, score=22.0]; MalT-like TPR region [PF17874.3, score=21.7]} {Human: ENSG00000032742, IFT88, intraflagellar transport 88, [RH, Score=867, Expect=0.0]} {Mouse: ENSMUSG00000040040, Ift88, intraflagellar transport 88, [RH, Score=908, Expect=0.0]} {Dmel: FBgn0016919, nompB, no mechanoreceptor potential B, [RH, Score=349, Expect=1e-107]} {Celegans: WBGene00003885, osm-5, OSM-5, [RH, Score=624, Expect=0.0]} {Smed: dd_Smed_v6_5484_0_1, dd_Smed_v6_5484_0_1, [RH, Score=976, Expect=0.0]} {RNA1509_34996, RNA1509_4056} {RNA1310_1829, RNA1509_34996, RNA1509_4056} {RNA1509_34996, RNA1509_4056, RNA815_705}
60. MligTC455_45949 4322 90.03 Mlig455_003487

Neo: -

Age: logFC(26M/2M)=-0.316

 MNS1 0.992 - - - - 0.992 - Mlig455_003487 {REF} {Length: 2175} {TRANSSPLICED} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=239.7]} {Human: ENSG00000138587, MNS1, meiosis specific nuclear structural 1, [RH, Score=312, Expect=9e-101]} {Mouse: ENSMUSG00000032221, Mns1, meiosis-specific nuclear structural protein 1, [RH, Score=338, Expect=5e-111]} {Smed: dd_Smed_v6_4463_0_1, dd_Smed_v6_4463_0_1, [RH, Score=380, Expect=2e-127]} {RNA1509_17543, RNA1509_30026, RNA1509_43231, RNA1509_5133, RNA1509_8697} {RNA1310_11484, RNA1509_17543, RNA1509_30026, RNA1509_43231, RNA1509_5133, RNA1509_8697} {RNA1509_17543, RNA1509_30026, RNA1509_43231, RNA1509_5133, RNA1509_8697, RNA815_4005}
61. MligTC455_28835 609 12.69 Mlig455_017390, Mlig455_017468

Neo: -

Age: Up-Down-Up

 C22orf23 0.979 - - - - - 0.979

Mlig455_017390 {REF} {Length: 2413} {Pfam: Uncharacterised protein family (UPF0193) [PF05250.13, score=201.6]} {Human: ENSG00000128346, C22orf23, chromosome 22 open reading frame 23, [RH, Score=123, Expect=2e-34]} {Mouse: ENSMUSG00000033029, 1700088E04Rik, RIKEN cDNA 1700088E04 gene, [RH, Score=131, Expect=1e-37]} {Dmel: FBgn0035952, CG5280, [RH, Score=65.5, Expect=1e-12]} {Smed: dd_Smed_v6_9772_0_1, dd_Smed_v6_9772_0_1, [RH, Score=165, Expect=5e-51]} {RNA1509_21354} {RNA1310_28343} {RNA815_10518}

Mlig455_017468 {REF} {Length: 2380} {Pfam: Uncharacterised protein family (UPF0193) [PF05250.13, score=201.6]} {Human: ENSG00000128346, C22orf23, chromosome 22 open reading frame 23, [RH, Score=123, Expect=2e-34]} {Mouse: ENSMUSG00000033029, 1700088E04Rik, RIKEN cDNA 1700088E04 gene, [RH, Score=131, Expect=1e-37]} {Dmel: FBgn0035952, CG5280, [RH, Score=65.5, Expect=1e-12]} {Smed: dd_Smed_v6_9772_0_1, dd_Smed_v6_9772_0_1, [RH, Score=165, Expect=5e-51]} {RNA1509_21354, RNA1509_48392} {RNA1310_28343, RNA1509_21354, RNA1509_48392} {RNA1509_21354, RNA1509_48392, RNA815_10518}
62. MligTC455_28087 6126 127.63 Mlig455_000464, Mlig455_000543

Neo: -

Age: logFC(26M/2M)=-0.169

 AC069444.2, MAATS1 0.976 - - - - 0.976 -

Mlig455_000464 {REF} {Length: 2787} {TRANSSPLICED} {Pfam: Cilia- and flagella-associated protein 91 [PF14738.8, score=200.4]} {Human: ENSG00000183833, MAATS1, MYCBP associated and testis expressed 1, [Score=691, Expect=0.0]; ENSG00000285585, AC069444.2, novel protein, [Score=691, Expect=0.0]} {Mouse: ENSMUSG00000022805, Maats1, MYCBP-associated, testis expressed 1, [Score=645, Expect=0.0]} {Dmel: FBgn0032647, CG15143, [Score=83.2, Expect=5e-16]} {Smed: dd_Smed_v6_10405_0_1, dd_Smed_v6_10405_0_1, [RH, Score=375, Expect=5e-124]} {RNA1509_17495} {RNA1310_5889} {RNA815_2081}

Mlig455_000543 {REF} {Length: 2770} {TRANSSPLICED} {Pfam: Cilia- and flagella-associated protein 91 [PF14738.8, score=200.3]} {Human: ENSG00000285585, AC069444.2, novel protein, [RH, Score=764, Expect=0.0]; ENSG00000183833, MAATS1, MYCBP associated and testis expressed 1, [RH, Score=764, Expect=0.0]} {Mouse: ENSMUSG00000022805, Maats1, MYCBP-associated, testis expressed 1, [RH, Score=719, Expect=0.0]} {Dmel: FBgn0032647, CG15143, [RH, Score=112, Expect=4e-25]} {Smed: dd_Smed_v6_10405_0_1, dd_Smed_v6_10405_0_1, [RH, Score=391, Expect=5e-130]} {RNA1509_17495} {RNA1310_5889} {RNA815_2081}
63. MligTC455_22978 1713 35.69 Mlig455_009568

Neo: -

Age: -

 CFAP43 0.975 - - - - 0.975 - Mlig455_009568 {REF} {Length: 1031} {Human: ENSG00000197748, CFAP43, cilia and flagella associated protein 43, [Score=60.5, Expect=8e-12]} {Mouse: ENSMUSG00000044948, Cfap43, cilia and flagella associated protein 43, [Score=56.6, Expect=1e-10]} {Smed: dd_Smed_v6_10271_0_3, dd_Smed_v6_10271_0_3, [Score=71.2, Expect=3e-16]} {RNA1509_53795} {RNA1310_29288} {RNA815_196.1}
64. MligTC455_22979 1736 36.17 Mlig455_061961

Neo: -

Age: logFC(26M/2M)=-0.302

 CFAP43 0.974 - - - - 0.974 - Mlig455_061961 {REF} {Length: 5985} {Human: ENSG00000197748, CFAP43, cilia and flagella associated protein 43, [RH, Score=528, Expect=5e-164]} {Mouse: ENSMUSG00000044948, Cfap43, cilia and flagella associated protein 43, [Score=554, Expect=2e-167]} {Dmel: FBgn0036348, CG17687, [RH, Score=118, Expect=3e-26]} {Smed: dd_Smed_v6_10271_0_1, dd_Smed_v6_10271_0_1, [Score=724, Expect=0.0]} {RNA1509_53795} {RNA1310_1696} {RNA815_196.1}
65. MligTC455_21974 1557 32.43 Mlig455_021416

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.546

Region-specific R2: 3.190

Region-enriched R2: 2.971/0.00000

 BMPER 0.973 - - - - - 0.973 Mlig455_021416 {REF} {Length: 22453} {Pfam: Domain of unknown function (DUF1943) [PF09172.13, score=157.5]; von Willebrand factor type D domain [PF00094.27, score=57.2]; Domain of Unknown Function (DUF1081) [PF06448.13, score=32.7]; C8 domain [PF08742.13, score=24.8]; Neurensin [PF14927.8, score=24.5]} {Human: ENSG00000164619, BMPER, BMP binding endothelial regulator, [Score=79.0, Expect=2e-13]; ENSG00000135253, KCP, kielin/chordin-like protein, [Score=79.0, Expect=3e-13]; ENSG00000275395, FCGBP, Fc fragment of IgG binding protein, [Score=76.6, Expect=2e-12]} {Mouse: ENSMUSG00000031963, Bmper, BMP-binding endothelial regulator, [Score=77.0, Expect=6e-13]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=226, Expect=7e-58]} {Smed: dd_Smed_v6_194_0_1, dd_Smed_v6_194_0_1, [Score=241, Expect=9e-63]} {RNA1509_31} {RNA1310_7.1} {RNA815_4}
66. MligTC455_21975 1445 30.1 Mlig455_067235

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.598

Region-specific R2: 3.235

Region-enriched R2: 3.090/0.00000

 BMPER 0.973 - - - - - 0.973 Mlig455_067235 {REF} {Length: 21751} {Pfam: von Willebrand factor type D domain [PF00094.27, score=57.1]; C8 domain [PF08742.13, score=24.9]; Neurensin [PF14927.8, score=24.8]} {Human: ENSG00000164619, BMPER, BMP binding endothelial regulator, [Score=80.9, Expect=4e-14]; ENSG00000135253, KCP, kielin/chordin-like protein, [Score=78.6, Expect=4e-13]; ENSG00000275395, FCGBP, Fc fragment of IgG binding protein, [Score=78.6, Expect=5e-13]} {Mouse: ENSMUSG00000031963, Bmper, BMP-binding endothelial regulator, [Score=78.6, Expect=2e-13]} {Dmel: FBgn0032136, Apoltp, Apolipoprotein lipid transfer particle, [Score=226, Expect=6e-58]} {Smed: dd_Smed_v6_194_0_1, dd_Smed_v6_194_0_1, [Score=244, Expect=8e-64]} {RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_31, RNA1509_5282} {RNA1310_7.1, RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_5282} {RNA1509_13513, RNA1509_26457, RNA1509_30456, RNA1509_5282, RNA815_4}
67. MligTC455_54157 234 4.88 Mlig455_058424

Neo: -

Age: -

 PPP1R36 0.973 - - - - - 0.973 Mlig455_058424 {REF} {Length: 2441} {Pfam: Protein phosphatase 1 inhibitor [PF14895.8, score=139.0]} {Human: ENSG00000165807, PPP1R36, protein phosphatase 1 regulatory subunit 36, [RH, Score=191, Expect=1e-55]} {Mouse: ENSMUSG00000052221, Ppp1r36, protein phosphatase 1, regulatory subunit 36, [RH, Score=167, Expect=5e-47]} {RNA1509_6292} {RNA1310_2911.1} {RNA815_5971.1}
68. MligTC455_18562 1101 22.94 Mlig455_068413

Neo: -

Age: logFC(26M/2M)=-0.313

 FADS2 0.971 - - - - 0.971 - Mlig455_068413 {REF} {Length: 2145} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=68.7]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=64.2]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [Score=266, Expect=1e-84]; ENSG00000149485, FADS1, fatty acid desaturase 1, [Score=259, Expect=6e-81]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [Score=284, Expect=2e-91]} {Dmel: FBgn0036575, CG5157, [Score=52.8, Expect=2e-08]} {Celegans: WBGene00001396, fat-4, Delta(5) fatty acid desaturase fat-4, [Score=71.6, Expect=1e-13]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=303, Expect=1e-99]} {RNA1509_14914, RNA1509_5162} {RNA1310_21305, RNA1509_14914, RNA1509_5162} {RNA1509_14914, RNA1509_5162, RNA815_8529}
69. MligTC455_18561 1106 23.05 Mlig455_038719

Neo: -

Age: -

 FADS2 0.97 - - - - 0.970 - Mlig455_038719 {REF} {Length: 2690} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=107.2]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=64.3]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [Score=410, Expect=1e-140]; ENSG00000149485, FADS1, fatty acid desaturase 1, [Score=402, Expect=8e-137]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [Score=426, Expect=3e-147]} {Dmel: FBgn0036575, CG5157, [Score=52.8, Expect=2e-08]} {Celegans: WBGene00001396, fat-4, Delta(5) fatty acid desaturase fat-4, [Score=124, Expect=2e-31]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [RH, Score=494, Expect=2e-174]} {RNA1509_5162, RNA1509_59484} {RNA1310_21305, RNA1509_59484} {RNA1509_59484, RNA815_8529}
70. MligTC455_48101 874 18.2 Mlig455_018395, Mlig455_069529

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.420/0.02237

 LRRC71 0.97 - - - - - 0.970

Mlig455_018395 {REF} {Length: 2255} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=67.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=25.6]; Leucine Rich Repeat [PF00560.35, score=24.4]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=199, Expect=3e-56]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=195, Expect=4e-55]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=230, Expect=1e-69]} {RNA1509_18089} {RNA1310_2341.2} {RNA815_677.1}

Mlig455_069529 {REF} {Length: 2441} {TRANSSPLICED} {Pfam: Leucine Rich repeat [PF13516.8, score=66.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=25.2]; Leucine Rich Repeat [PF00560.35, score=24.2]} {Human: ENSG00000160838, LRRC71, leucine rich repeat containing 71, [RH, Score=202, Expect=2e-57]} {Mouse: ENSMUSG00000023084, Lrrc71, leucine rich repeat containing 71, [RH, Score=198, Expect=4e-56]} {Smed: dd_Smed_v6_12043_0_2, dd_Smed_v6_12043_0_2, [RH, Score=227, Expect=2e-68]} {RNA1509_18089} {RNA1310_2341.2, RNA1509_18089} {RNA1509_18089, RNA815_677.1}
71. MligTC455_20869 354 7.38 Mlig455_048463

Neo: -

Age: -

 SARAF 0.969 - - - - - 0.969 Mlig455_048463 {REF} {Length: 3486} {Pfam: SOCE-associated regulatory factor of calcium homoeostasis [PF06682.14, score=201.6]} {Human: ENSG00000133872, SARAF, store-operated calcium entry associated regulatory factor, [Score=136, Expect=2e-37]} {Mouse: ENSMUSG00000031532, Saraf, store-operated calcium entry-associated regulatory factor, [Score=126, Expect=1e-33]} {Celegans: WBGene00011529, T06D8.9, [Score=122, Expect=1e-32]} {Smed: dd_Smed_v6_809_0_1, dd_Smed_v6_809_0_1, [Score=154, Expect=2e-45]} {RNA1509_37606} {RNA1310_29107} {RNA815_13291}
72. MligTC455_12970 132 2.76 Mlig455_022445

Neo: -

Age: logFC(26M/2M)=-1.642

 0.967 - - - - - 0.967 Mlig455_022445 {REF} {Length: 1567} {Pfam: WSC domain [PF01822.21, score=52.5]; PAN domain [PF00024.28, score=21.7]} {RNA1509_43359} {RNA1310_32360, RNA1509_43359} {RNA1509_43359, RNA815_34556}
73. MligTC455_38105 2374 49.46 Mlig455_015942

Neo: -

Age: logFC(26M/2M)=-0.373

 AK9 0.965 - - - - 0.965 - Mlig455_015942 {REF} {Length: 6588} {Pfam: Adenylate kinase [PF00406.24, score=148.4]; AAA domain [PF13207.8, score=69.1]; Domain of unknown function [PF12018.10, score=55.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=38.2]; AAA domain [PF13238.8, score=35.5]; YHS domain [PF04945.15, score=34.7]; AAA domain [PF13479.8, score=31.0]; AAA domain [PF13671.8, score=30.4]; AAA domain [PF13401.8, score=23.9]; Hydin Adenylate kinase-like domain [PF17213.5, score=21.5]; RNA helicase [PF00910.24, score=19.7]; AAA domain [PF13521.8, score=19.6]} {Human: ENSG00000155085, AK9, adenylate kinase 9, [RH, Score=1089, Expect=0.0]} {Mouse: ENSMUSG00000091415, Ak9, adenylate kinase 9, [RH, Score=1080, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=54.3, Expect=2e-07]} {Celegans: WBGene00009575, F40F8.1, UMP-CMP kinase 2, [Score=58.9, Expect=3e-09]} {Smed: dd_Smed_v6_9617_0_1, dd_Smed_v6_9617_0_1, [RH, Score=863, Expect=0.0]} {RNA1509_1039} {RNA1310_346} {RNA815_505}
74. MligTC455_22570 261 5.44 Mlig455_006659

Neo: -

Age: -

Region-enriched R2: 3.042/0.02689

 0.963 - - - - - 0.963 Mlig455_006659 {REF} {Length: 918} {NoTransDecoderORF} {RNA1509_10005} {RNA1310_56340} {RNA815_38610}
75. MligTC455_42016 575 11.98 Mlig455_045707, Mlig455_071028

Neo: -

Age: -

 SLMAP 0.963 - - - 0.963 - -

Mlig455_045707 {REF} {Length: 3632} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=52.2]} {Human: ENSG00000163681, SLMAP, sarcolemma associated protein, [Score=118, Expect=5e-27]} {Mouse: ENSMUSG00000021870, Slmap, sarcolemma associated protein, [Score=116, Expect=9e-27]} {Dmel: FBgn0040011, Slmap, Sarcolemma associated protein, [Score=94.7, Expect=7e-20]} {Celegans: WBGene00019766, M4.1, [Score=100, Expect=6e-22]} {Smed: dd_Smed_v6_3763_0_5, dd_Smed_v6_3763_0_5, [Score=95.5, Expect=8e-21]} {RNA1509_20105} {RNA1310_3398.1} {RNA815_4914}

Mlig455_071028 {REF} {Length: 3741} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=52.3]} {Human: ENSG00000163681, SLMAP, sarcolemma associated protein, [Score=116, Expect=2e-26]} {Mouse: ENSMUSG00000021870, Slmap, sarcolemma associated protein, [Score=115, Expect=3e-26]} {Dmel: FBgn0040011, Slmap, Sarcolemma associated protein, [Score=97.1, Expect=1e-20]} {Celegans: WBGene00019766, M4.1, [Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_3763_0_5, dd_Smed_v6_3763_0_5, [Score=96.3, Expect=5e-21]} {RNA1509_20105} {RNA1310_3398.1, RNA1509_20105} {RNA1509_20105, RNA815_4914}
76. MligTC455_49485 10924 227.58 Mlig455_045426

Neo: -

Age: logFC(26M/2M)=-0.286

Region-enriched R2: 1.070/0.00000

 PCCB 0.963 - - - - 0.963 - Mlig455_045426 {REF} {Length: 1500} {Pfam: Carboxyl transferase domain [PF01039.24, score=326.0]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=24.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [Score=393, Expect=8e-137]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [Score=393, Expect=7e-136]} {Dmel: FBgn0042083, CG3267, [Score=122, Expect=1e-31]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [Score=385, Expect=4e-133]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [Score=428, Expect=2e-149]} {RNA1509_1810} {RNA1310_10357.1} {RNA815_3334.1}
77. MligTC455_49842 391 8.14 Mlig455_030095

Neo: -

Age: Down-Up-Up

 0.962 - - - - - 0.962 Mlig455_030095 {REF} {Length: 2464} {TRANSSPLICED} {RNA1509_54601} {RNA1310_30894.2, RNA1509_54601} {RNA1509_54601, RNA815_35555}
78. MligTC455_18348 399 8.3 Mlig455_057138

Neo: -

Age: logFC(26M/2M)=-0.655

 KCNA3 0.961 - - - - 0.961 - Mlig455_057138 {REF} {Length: 2324} {Pfam: Ion transport protein [PF00520.33, score=161.8]; BTB/POZ domain [PF02214.24, score=97.8]; Ion channel [PF07885.18, score=49.9]} {Human: ENSG00000177272, KCNA3, potassium voltage-gated channel subfamily A member 3, [RH, Score=613, Expect=0.0]; ENSG00000177301, KCNA2, potassium voltage-gated channel subfamily A member 2, [RH, Score=612, Expect=0.0]; ENSG00000111262, KCNA1, potassium voltage-gated channel subfamily A member 1, [RH, Score=607, Expect=0.0]; ENSG00000182255, KCNA4, potassium voltage-gated channel subfamily A member 4, [RH, Score=590, Expect=0.0]} {Mouse: ENSMUSG00000040724, Kcna2, potassium voltage-gated channel, shaker-related subfamily, member 2, [RH, Score=611, Expect=0.0]; ENSMUSG00000047959, Kcna3, potassium voltage-gated channel, shaker-related subfamily, member 3, [RH, Score=610, Expect=0.0]; ENSMUSG00000047976, Kcna1, potassium voltage-gated channel, shaker-related subfamily, member 1, [RH, Score=607, Expect=0.0]; ENSMUSG00000042604, Kcna4, potassium voltage-gated channel, shaker-related subfamily, member 4, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0003380, Sh, Shaker, [RH, Score=630, Expect=0.0]} {Celegans: WBGene00014261, shk-1, Potassium voltage-gated channel protein shk-1, [RH, Score=377, Expect=3e-124]} {Smed: dd_Smed_v6_15425_0_1, dd_Smed_v6_15425_0_1, [RH, Score=714, Expect=0.0]} {RNA1509_21830} {RNA1310_8777} {RNA815_4701}
79. MligTC455_27220 3965 82.6 Mlig455_007059

Neo: -

Age: logFC(26M/2M)=-0.158

 TEKT2 0.961 - - - - 0.961 - Mlig455_007059 {REF} {Length: 2591} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=425.6]} {Human: ENSG00000092850, TEKT2, tektin 2, [RH, Score=421, Expect=5e-145]} {Mouse: ENSMUSG00000028845, Tekt2, tektin 2, [RH, Score=387, Expect=4e-132]} {Dmel: FBgn0034816, CG3085, [RH, Score=213, Expect=2e-64]} {Celegans: WBGene00019828, R02E12.4, [Score=78.2, Expect=2e-15]} {Smed: dd_Smed_v6_2339_0_1, dd_Smed_v6_2339_0_1, [RH, Score=543, Expect=0.0]} {RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859} {RNA1310_13089.2, RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859} {RNA1509_1922, RNA1509_21664, RNA1509_27270, RNA1509_30387, RNA1509_30865, RNA1509_3752, RNA1509_44905, RNA1509_58859, RNA815_4479}
80. MligTC455_43615 1202 25.04 Mlig455_024404

Neo: -

Age: logFC(26M/2M)=-0.268

 CFAP57 0.96 - - - - 0.960 - Mlig455_024404 {REF} {Length: 5259} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=66.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=23.3]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=19.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=494, Expect=2e-154]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.5, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1619, Expect=0.0]} {RNA1509_18223, RNA1509_836} {RNA1310_1737, RNA1509_18223, RNA1509_836} {RNA1509_18223, RNA1509_836, RNA815_558}
81. MligTC455_45397 2373 49.43 Mlig455_031265, Mlig455_031311

Neo: -

Age: logFC(26M/2M)=-0.486

Region-enriched R2: 1.539/0.00242
Region-enriched R3: 1.339/0.00095

 TEX47 0.96 - - - - - 0.960

Mlig455_031265 {REF} {Length: 1234} {Human: ENSG00000164645, TEX47, testis expressed 47, [RH, Score=80.5, Expect=3e-17]} {Mouse: ENSMUSG00000040514, Tex47, testis expressed 47, [RH, Score=72.0, Expect=2e-14]} {Smed: dd_Smed_v6_11000_0_1, dd_Smed_v6_11000_0_1, [RH, Score=151, Expect=9e-45]} {RNA1509_19625, RNA1509_5428} {RNA1310_27895, RNA1509_19625, RNA1509_5428} {RNA1509_19625, RNA1509_5428, RNA815_12847}

Mlig455_031311 {REF} {Length: 1268} {Human: ENSG00000164645, TEX47, testis expressed 47, [RH, Score=79.7, Expect=5e-17]} {Mouse: ENSMUSG00000040514, Tex47, testis expressed 47, [RH, Score=71.6, Expect=2e-14]} {Smed: dd_Smed_v6_11000_0_1, dd_Smed_v6_11000_0_1, [RH, Score=151, Expect=1e-44]} {RNA1509_19625} {RNA1310_27895} {RNA815_12847}
82. MligTC455_36772 6747 140.56 Mlig455_056711

Neo: -

Age: logFC(26M/2M)=-0.295

 PIFO 0.959 - - - - - 0.959 Mlig455_056711 {REF} {Length: 1169} {Pfam: Sperm-tail PG-rich repeat [PF07004.14, score=25.0]} {Human: ENSG00000173947, PIFO, primary cilia formation, [RH, Score=82.4, Expect=5e-19]} {Mouse: ENSMUSG00000010136, Pifo, primary cilia formation, [RH, Score=84.7, Expect=5e-20]} {Smed: dd_Smed_v6_5490_0_1, dd_Smed_v6_5490_0_1, [RH, Score=149, Expect=4e-45]} {RNA1509_1959, RNA1509_7367} {RNA1310_34451.1, RNA1509_1959, RNA1509_7367} {RNA1509_1959, RNA1509_7367, RNA815_15938}
83. MligTC455_21297 546 11.38 Mlig455_033973

Neo: Germline

Age: Up-Down-Up

 0.958 - - - - - 0.958 Mlig455_033973 {REF} {Length: 4638} {RNA1509_49102} {RNA1310_24684} {RNA815_56598}
84. MligTC455_36245 490 10.21 Mlig455_060055

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.650

 0.957 - - - - 0.957 - Mlig455_060055 {REF} {Length: 582} {NoTransDecoderORF} {RNA1509_29797, RNA1509_55333} {RNA1310_38449, RNA1509_29797, RNA1509_55333} {RNA1509_29797, RNA1509_55333, RNA815_2803.2}
85. MligTC455_25133 2937 61.18 Mlig455_010481

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.642

 0.956 - - - - 0.956 - Mlig455_010481 {REF} {Length: 3233} {RNA1509_20130, RNA1509_27443, RNA1509_30748, RNA1509_33458} {RNA1310_7129.1, RNA1509_27443, RNA1509_30748, RNA1509_33458} {RNA1509_27443, RNA1509_30748, RNA1509_33458, RNA815_2628}
86. MligTC455_32560 474 9.88 Mlig455_005052

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_005052 {REF} {Length: 3173} {Smed: dd_Smed_v6_9637_0_1, dd_Smed_v6_9637_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_2854} {RNA1310_3474} {RNA815_179}
87. MligTC455_29450 827 17.23 Mlig455_026424

Neo: -

Age: logFC(26M/2M)=-0.523

 LMNTD1 0.954 - - - - 0.954 - Mlig455_026424 {REF} {Length: 3702} {Pfam: Intermediate filament protein [PF00038.23, score=52.8]; Lamin Tail Domain [PF00932.21, score=40.5]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=142, Expect=7e-36]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.8, Expect=9e-13]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.4, Expect=9e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=228, Expect=1e-62]} {RNA1509_16713, RNA1509_7063} {RNA1310_3989.1, RNA1509_16713, RNA1509_7063} {RNA1509_16713, RNA1509_7063, RNA815_1147.1}
88. MligTC455_42966 424 8.83 Mlig455_065372

Neo: -

Age: logFC(26M/2M)=-0.345

 SPATA6L 0.953 - - - - - 0.953 Mlig455_065372 {REF} {Length: 3682} {TRANSSPLICED} {Pfam: Spermatogenesis-assoc protein 6 [PF14909.8, score=127.3]} {Human: ENSG00000106686, SPATA6L, spermatogenesis associated 6 like, [RH, Score=95.9, Expect=8e-22]} {Mouse: ENSMUSG00000064202, 4430402I18Rik, RIKEN cDNA 4430402I18 gene, [RH, Score=100, Expect=6e-23]} {Smed: dd_Smed_v6_10543_0_1, dd_Smed_v6_10543_0_1, [RH, Score=186, Expect=1e-55]} {RNA1509_23645} {RNA1310_24559, RNA1509_23645} {RNA1509_23645, RNA815_31401}
89. MligTC455_19465 216 4.5 Mlig455_011567

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.898

Region-enriched R2: 2.709/0.02014

 LRRC69 0.952 - - - - - 0.952 Mlig455_011567 {REF} {Length: 2449} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=92.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=80.1]; Leucine Rich repeat [PF13516.8, score=33.3]; Leucine Rich Repeat [PF00560.35, score=27.4]} {Human: ENSG00000214954, LRRC69, leucine rich repeat containing 69, [RH, Score=198, Expect=7e-60]} {Mouse: ENSMUSG00000023151, Lrrc69, leucine rich repeat containing 69, [RH, Score=218, Expect=1e-67]} {Dmel: FBgn0033984, Lap1, [Score=105, Expect=3e-24]} {Celegans: WBGene00002632, let-413, [Score=112, Expect=8e-27]} {Smed: dd_Smed_v6_14722_0_1, dd_Smed_v6_14722_0_1, [RH, Score=184, Expect=5e-56]} {RNA1509_41102} {RNA1310_3215.1} {RNA815_13052}
90. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

 LMNTD1 0.952 - - - - 0.952 - Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
91. MligTC455_47383 2319 48.32 Mlig455_049031, Mlig455_063739

Neo: -

Age: logFC(26M/2M)=1.164

 0.952 - - - - 0.952 -

Mlig455_049031 {REF} {Length: 1477} {RNA1509_16827} {RNA1310_19392.1} {RNA815_20667}

Mlig455_063739 {REF} {Length: 5644} {RNA1509_9711} {RNA1310_19392.1} {RNA815_20667}
92. MligTC455_25134 2209 46.03 Mlig455_061897

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.237

 0.951 - - - - 0.951 - Mlig455_061897 {REF} {Length: 3533} {Pfam: BRICHOS domain [PF04089.16, score=21.8]} {RNA1509_20130, RNA1509_5762} {RNA1310_7129.1, RNA1509_20130, RNA1509_5762} {RNA1509_20130, RNA1509_5762, RNA815_2628}
93. MligTC455_28447 1671 34.81 Mlig455_066308

Neo: -

Age: Down-Up-Down

 0.951 - - - - - 0.951 Mlig455_066308 {REF} {Length: 1281} {Pfam: Domain of unknown function (DUF4515) [PF14988.8, score=104.5]} {Mouse: ENSMUSG00000098176, Ccdc166, coiled-coil domain containing 166, [RH, Score=107, Expect=4e-26]} {Smed: dd_Smed_v6_13384_0_1, dd_Smed_v6_13384_0_1, [RH, Score=124, Expect=2e-33]} {RNA1509_33127} {RNA1310_32791.1, RNA1509_33127} {RNA1509_33127, RNA815_15652}
94. MligTC455_40419 6115 127.39 Mlig455_055666

Neo: -

Age: Down-Down-Up

Region-enriched R4: 1.043/0.00005

Regeneration-depleted R4: -1.023
Regeneration-depleted R6: -1.010

 PIH1D1 0.951 - - - - - 0.951 Mlig455_055666 {REF} {Length: 3753} {Pfam: PIH1 N-terminal domain [PF08190.14, score=96.7]; PIH1 CS-like domain [PF18201.3, score=47.8]} {Human: ENSG00000104872, PIH1D1, PIH1 domain containing 1, [RH, Score=136, Expect=2e-36]} {Mouse: ENSMUSG00000003423, Pih1d1, PIH1 domain containing 1, [RH, Score=147, Expect=1e-40]} {Dmel: FBgn0032455, Pih1D1, [RH, Score=116, Expect=7e-29]} {Smed: dd_Smed_v6_7684_0_1, dd_Smed_v6_7684_0_1, [RH, Score=189, Expect=2e-56]} {RNA1509_28944, RNA1509_57670} {RNA1310_29390.1, RNA1509_57670} {RNA1509_57670, RNA815_11271.1}
95. MligTC455_25030 401 8.35 Mlig455_014751

Neo: -

Age: Down-Up-Down

 0.95 - - - - 0.950 - Mlig455_014751 {REF} {Length: 2349} {RNA1509_19923} {RNA1310_20222} {RNA815_2554}
96. MligTC455_27509 515 10.73 Mlig455_023080

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.476

 0.95 - - - - 0.950 - Mlig455_023080 {REF} {Length: 2939} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=39.0]; Ankyrin repeats (many copies) [PF13637.8, score=31.8]; Ankyrin repeat [PF00023.32, score=30.0]; Ankyrin repeat [PF13606.8, score=29.3]; Ankyrin repeats (many copies) [PF13857.8, score=24.6]} {Smed: dd_Smed_v6_16174_0_1, dd_Smed_v6_16174_0_1, [Score=48.5, Expect=2e-06]} {RNA1509_26758} {RNA1310_10050} {RNA815_9030.1}
97. MligTC455_38601 233 4.86 Mlig455_028048, Mlig455_028113

Neo: -

Age: -

 CCDC87 0.95 - - - - 0.950 -

Mlig455_028048 {REF} {Length: 3136} {Mouse: ENSMUSG00000067872, Ccdc87, coiled-coil domain containing 87, [Score=57.0, Expect=7e-08]} {Smed: dd_Smed_v6_12480_0_1, dd_Smed_v6_12480_0_1, [Score=145, Expect=6e-36]} {RNA1509_8830} {RNA1310_2448.2} {RNA815_4309}

Mlig455_028113 {REF} {Length: 4779} {Pfam: Microtubule associated protein (MAP65/ASE1 family) [PF03999.14, score=22.7]} {Human: ENSG00000182791, CCDC87, coiled-coil domain containing 87, [RH, Score=116, Expect=8e-26]} {Mouse: ENSMUSG00000067872, Ccdc87, coiled-coil domain containing 87, [RH, Score=112, Expect=1e-24]} {Smed: dd_Smed_v6_12480_0_1, dd_Smed_v6_12480_0_1, [RH, Score=326, Expect=6e-96]} {RNA1509_8830} {RNA1310_2448.2} {RNA815_4309}
98. MligTC455_40875 441 9.2 Mlig455_013461

Neo: -

Age: Up-Down-Down

 ATP10B 0.95 - - - - 0.950 - Mlig455_013461 {REF} {Length: 5549} {TRANSSPLICED} {Pfam: Phospholipid-translocating P-type ATPase C-terminal [PF16212.7, score=164.9]; Phospholipid-translocating ATPase N-terminal [PF16209.7, score=81.0]; haloacid dehalogenase-like hydrolase [PF00702.28, score=44.4]; Cation transport ATPase (P-type) [PF13246.8, score=42.9]; E1-E2 ATPase [PF00122.22, score=27.9]} {Human: ENSG00000118322, ATP10B, ATPase phospholipid transporting 10B (putative), [RH, Score=902, Expect=0.0]} {Mouse: ENSMUSG00000055415, Atp10b, ATPase, class V, type 10B, [RH, Score=898, Expect=0.0]} {Dmel: FBgn0030747, CG4301, [Score=498, Expect=9e-153]} {Celegans: WBGene00012360, tat-3, Phospholipid-transporting ATPase, [RH, Score=885, Expect=0.0]} {Smed: dd_Smed_v6_5042_0_1, dd_Smed_v6_5042_0_1, [RH, Score=1040, Expect=0.0]} {RNA1509_11694} {RNA1310_793} {RNA815_3912}
99. MligTC455_54077 937 19.53 Mlig455_032159, Mlig455_032165

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.640

 TLL2 0.95 - - - - 0.950 -

Mlig455_032159 {REF} {Length: 1358} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}

Mlig455_032165 {REF} {Length: 1696} {Pfam: CUB domain [PF00431.22, score=63.7]} {Human: ENSG00000095587, TLL2, tolloid like 2, [Score=62.8, Expect=4e-10]; ENSG00000107611, CUBN, cubilin, [Score=62.0, Expect=1e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=61.2, Expect=1e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=68.9, Expect=4e-12]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}

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