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Results for MligTC455_49484

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49484 10996 229.08 Mlig455_045342

Neo: -

Age: logFC(26M/2M)=-0.289

Region-enriched R2: 1.032/0.00001

PCCB Mlig455_045342 {REF} {Length: 2338} {TRANSSPLICED} {Pfam: Carboxyl transferase domain [PF01039.24, score=621.7]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=25.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [RH, Score=789, Expect=0.0]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [RH, Score=785, Expect=0.0]} {Dmel: FBgn0042083, CG3267, [Score=235, Expect=6e-70]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [RH, Score=785, Expect=0.0]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [RH, Score=839, Expect=0.0]} {RNA1509_1631, RNA1509_328} {RNA1310_10357.1, RNA1509_1631} {RNA1509_1631, RNA815_3334.1}

Cumulative graph for MligTC455_49484

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.684 7.882 0.04442 0.50707
RegionR2 1.032 7.882 0.00000 0.00001
RegionR3 0.485 7.882 0.00232 0.05551
RegionR4 0.249 7.882 0.18083 0.45124
RegionR5 0.047 7.882 0.75986 1.00000
RegionR6 -0.009 7.882 0.95558 1.00000
RegionR7 -0.431 7.882 0.02564 0.30022
RegionR8 -0.689 7.882 0.00364 0.10560

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.417 7.882 0.33961 1.00000
RegenerationR2 0.355 7.882 0.05715 0.39269
RegenerationR3 0.185 7.882 0.35149 0.77173
RegenerationR4 -0.078 7.882 0.70443 0.95542
RegenerationR5 0.294 7.882 0.13375 0.54174
RegenerationR6 0.191 7.882 0.34232 0.68798
RegenerationBL 0.42 7.882 0.03392 0.20645
RegenerationTP 0.029 7.882 0.89815 1.00000


Genes with expression patterns similar to MligTC455_49484

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49484 10996 229.08 Mlig455_045342

Neo: -

Age: logFC(26M/2M)=-0.289

Region-enriched R2: 1.032/0.00001

PCCB 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_045342 {REF} {Length: 2338} {TRANSSPLICED} {Pfam: Carboxyl transferase domain [PF01039.24, score=621.7]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=25.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [RH, Score=789, Expect=0.0]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [RH, Score=785, Expect=0.0]} {Dmel: FBgn0042083, CG3267, [Score=235, Expect=6e-70]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [RH, Score=785, Expect=0.0]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [RH, Score=839, Expect=0.0]} {RNA1509_1631, RNA1509_328} {RNA1310_10357.1, RNA1509_1631} {RNA1509_1631, RNA815_3334.1}
2. MligTC455_49485 10924 227.58 Mlig455_045426

Neo: -

Age: logFC(26M/2M)=-0.286

Region-enriched R2: 1.070/0.00000

PCCB 5.987 0.997 0.999 0.993 1.000 0.999 0.999 Mlig455_045426 {REF} {Length: 1500} {Pfam: Carboxyl transferase domain [PF01039.24, score=326.0]; Malonate decarboxylase gamma subunit (MdcE) [PF06833.13, score=24.8]} {Human: ENSG00000114054, PCCB, propionyl-CoA carboxylase subunit beta, [Score=393, Expect=8e-137]} {Mouse: ENSMUSG00000032527, Pccb, propionyl Coenzyme A carboxylase, beta polypeptide, [Score=393, Expect=7e-136]} {Dmel: FBgn0042083, CG3267, [Score=122, Expect=1e-31]} {Celegans: WBGene00018701, pccb-1, Propionyl Coenzyme A Carboxylase Beta subunit, [Score=385, Expect=4e-133]} {Smed: dd_Smed_v6_513_0_1, dd_Smed_v6_513_0_1, [Score=428, Expect=2e-149]} {RNA1509_1810} {RNA1310_10357.1} {RNA815_3334.1}
3. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

CEP164 5.065 0.746 0.767 0.869 0.835 0.896 0.952

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}
4. MligTC455_19760 6101 127.11 Mlig455_004980, Mlig455_005294

Neo: -

Age: logFC(26M/2M)=-0.196

DNAI1 4.373 - 0.723 0.866 0.917 0.964 0.903

Mlig455_004980 {REF} {Length: 2735} {Pfam: WD domain, G-beta repeat [PF00400.34, score=34.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.3]} {Human: ENSG00000122735, DNAI1, dynein axonemal intermediate chain 1, [RH, Score=773, Expect=0.0]} {Mouse: ENSMUSG00000061322, Dnaic1, dynein, axonemal, intermediate chain 1, [RH, Score=773, Expect=0.0]} {Dmel: FBgn0034566, CG9313, [RH, Score=522, Expect=1e-176]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=112, Expect=9e-26]} {Smed: dd_Smed_v6_4753_0_1, dd_Smed_v6_4753_0_1, [RH, Score=858, Expect=0.0]} {RNA1509_16663, RNA1509_31620, RNA1509_34544, RNA1509_36463, RNA1509_40409, RNA1509_41706, RNA1509_51014} {RNA1310_13300.1, RNA1509_16663, RNA1509_31620, RNA1509_34544, RNA1509_36463, RNA1509_40409, RNA1509_41706} {RNA1509_16663, RNA1509_31620, RNA1509_34544, RNA1509_36463, RNA1509_40409, RNA1509_41706, RNA815_2412.1}

Mlig455_005294 {REF} {Length: 2692} {Pfam: WD domain, G-beta repeat [PF00400.34, score=34.6]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=29.5]} {Human: ENSG00000122735, DNAI1, dynein axonemal intermediate chain 1, [RH, Score=772, Expect=0.0]} {Mouse: ENSMUSG00000061322, Dnaic1, dynein, axonemal, intermediate chain 1, [RH, Score=772, Expect=0.0]} {Dmel: FBgn0034566, CG9313, [RH, Score=525, Expect=6e-178]} {Celegans: WBGene00015927, dyci-1, DYnein Chain, light Intermediate, [Score=112, Expect=9e-26]} {Smed: dd_Smed_v6_4753_0_1, dd_Smed_v6_4753_0_1, [RH, Score=860, Expect=0.0]} {RNA1509_51014} {RNA1310_13300.1} {RNA815_2412.1}
5. MligTC455_30354 7076 147.42 Mlig455_048268

Neo: -

Age: Down-Up-Up

Region-enriched R2: 2.672/0.00021

TUBB4B 4.012 0.726 0.834 0.706 - 0.957 0.789 Mlig455_048268 {REF} {Length: 1406} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=144.2]; Tubulin C-terminal domain [PF03953.19, score=102.9]} {Human: ENSG00000188229, TUBB4B, tubulin beta 4B class IVb, [Score=615, Expect=0.0]; ENSG00000137285, TUBB2B, tubulin beta 2B class IIb, [Score=612, Expect=0.0]; ENSG00000229684, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000183311, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000232575, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000137267, TUBB2A, tubulin beta 2A class IIa, [Score=610, Expect=0.0]; ENSG00000227739, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000196230, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000232421, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000224156, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000235067, TUBB, tubulin beta class I, [Score=610, Expect=0.0]; ENSG00000104833, TUBB4A, tubulin beta 4A class IVa, [Score=605, Expect=0.0]; ENSG00000258947, TUBB3, tubulin beta 3 class III, [Score=594, Expect=0.0]} {Mouse: ENSMUSG00000036752, Tubb4b, tubulin, beta 4B class IVB, [Score=615, Expect=0.0]; ENSMUSG00000045136, Tubb2b, tubulin, beta 2B class IIB, [Score=612, Expect=0.0]; ENSMUSG00000001525, Tubb5, tubulin, beta 5 class I, [Score=610, Expect=0.0]; ENSMUSG00000058672, Tubb2a, tubulin, beta 2A class IIA, [Score=610, Expect=0.0]; ENSMUSG00000062591, Tubb4a, tubulin, beta 4A class IVA, [Score=605, Expect=0.0]; ENSMUSG00000062380, Tubb3, tubulin, beta 3 class III, [Score=593, Expect=0.0]} {Dmel: FBgn0284243, betaTub56D, beta-Tubulin at 56D, [Score=607, Expect=0.0]} {Celegans: WBGene00006537, tbb-2, Tubulin beta-2 chain, [Score=573, Expect=0.0]} {Smed: dd_Smed_v6_83_0_2, dd_Smed_v6_83_0_2, [Score=615, Expect=0.0]} {RNA1509_4770} {RNA1310_20848.2} {RNA815_1610.2}
6. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 3.509 - - 0.902 0.751 0.892 0.964

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
7. MligTC455_15346 10495 218.65 Mlig455_014073, Mlig455_014091

Neo: -

Age: -

TEKT4 3.487 - - 0.818 0.839 0.976 0.854

Mlig455_014073 {REF} {Length: 1994} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=471.5]; Intermediate filament protein [PF00038.23, score=20.4]} {Human: ENSG00000163060, TEKT4, tektin 4, [RH, Score=404, Expect=3e-138]} {Mouse: ENSMUSG00000024175, Tekt4, tektin 4, [RH, Score=419, Expect=2e-144]} {Dmel: FBgn0028902, Tektin-A, Tektin A, [RH, Score=219, Expect=3e-65]} {Smed: dd_Smed_v6_4872_0_1, dd_Smed_v6_4872_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_689} {RNA1310_17094.1} {RNA815_4941}

Mlig455_014091 {REF} {Length: 1995} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=471.5]; Intermediate filament protein [PF00038.23, score=20.4]} {Human: ENSG00000163060, TEKT4, tektin 4, [RH, Score=404, Expect=3e-138]} {Mouse: ENSMUSG00000024175, Tekt4, tektin 4, [RH, Score=419, Expect=2e-144]} {Dmel: FBgn0028902, Tektin-A, Tektin A, [RH, Score=219, Expect=3e-65]} {Smed: dd_Smed_v6_4872_0_1, dd_Smed_v6_4872_0_1, [RH, Score=551, Expect=0.0]} {RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416} {RNA1310_17094.1, RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416} {RNA1509_19210, RNA1509_6710, RNA1509_689, RNA1509_9416, RNA815_4941}
8. MligTC455_54147 2046 42.63 Mlig455_062289

Neo: -

Age: Down-Up-Down

DRC7 3.45 - 0.728 - 0.945 0.984 0.793 Mlig455_062289 {REF} {Length: 3093} {Human: ENSG00000159625, DRC7, dynein regulatory complex subunit 7, [Score=642, Expect=0.0]} {Mouse: ENSMUSG00000031786, Drc7, dynein regulatory complex subunit 7, [Score=629, Expect=0.0]} {Dmel: FBgn0083946, lobo, lost boys, [Score=226, Expect=1e-61]} {Smed: dd_Smed_v6_12588_0_1, dd_Smed_v6_12588_0_1, [Score=588, Expect=0.0]} {RNA1509_1230} {RNA1310_4483} {RNA815_1294}
9. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

CFAP20 3.402 0.732 - 0.792 - 0.927 0.951 Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
10. MligTC455_41199 7523 156.73 Mlig455_001888, Mlig455_048783

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.793

CFAP45 3.399 - - 0.753 0.754 0.974 0.918

Mlig455_001888 {REF} {Length: 2583} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=192.2]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=301, Expect=2e-95]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=296, Expect=2e-93]} {Dmel: FBgn0037162, CG11449, [Score=100, Expect=4e-22]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=407, Expect=1e-136]} {RNA1509_2741} {RNA1310_7881.1} {RNA815_2376.1}

Mlig455_048783 {REF} {Length: 2929} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [RH, Score=371, Expect=6e-122]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [RH, Score=365, Expect=9e-120]} {Dmel: FBgn0037162, CG11449, [RH, Score=116, Expect=2e-27]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [RH, Score=478, Expect=5e-164]} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA1509_455} {RNA1310_7881.1, RNA1509_11068, RNA1509_22358, RNA1509_2741} {RNA1509_11068, RNA1509_22358, RNA1509_2741, RNA815_2376.1}
11. MligTC455_47923 9994 208.21 Mlig455_031159, Mlig455_031167

Neo: -

Age: logFC(26M/2M)=-0.423

CCDC63 3.382 0.709 - 0.797 - 0.964 0.912

Mlig455_031159 {REF} {Length: 2325} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=22.9]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [Score=181, Expect=9e-50]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [Score=163, Expect=3e-43]; ENSMUSG00000040189, Ccdc114, coiled-coil domain containing 114, [Score=158, Expect=3e-41]} {Dmel: FBgn0038452, CG14905, [Score=159, Expect=9e-43]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [Score=431, Expect=8e-146]} {RNA1509_2578, RNA1509_9264} {RNA1310_10129.1, RNA1509_2578, RNA1509_9264} {RNA1509_2578, RNA1509_9264, RNA815_3341.1}

Mlig455_031167 {REF} {Length: 2293} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=22.9]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [Score=181, Expect=9e-50]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [Score=163, Expect=3e-43]; ENSMUSG00000040189, Ccdc114, coiled-coil domain containing 114, [Score=158, Expect=3e-41]} {Dmel: FBgn0038452, CG14905, [Score=159, Expect=9e-43]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [Score=431, Expect=8e-146]} {RNA1509_1172, RNA1509_13163, RNA1509_16375, RNA1509_2578} {RNA1310_10129.1, RNA1509_1172, RNA1509_13163, RNA1509_16375} {RNA1509_1172, RNA1509_13163, RNA1509_16375, RNA815_3341.1}
12. MligTC455_27689 21816 454.5 Mlig455_035623

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.278

TUBA1A 3.375 0.719 - 0.870 - 0.951 0.835 Mlig455_035623 {REF} {Length: 2313} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=213.7]; Tubulin C-terminal domain [PF03953.19, score=176.0]; Tubulin domain [PF14881.8, score=19.3]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [Score=854, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [Score=853, Expect=0.0]; ENSG00000075886, TUBA3D, tubulin alpha 3d, [Score=845, Expect=0.0]; ENSG00000198033, TUBA3C, tubulin alpha 3c, [Score=845, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [Score=854, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [Score=853, Expect=0.0]; ENSMUSG00000067338, Tuba3b, tubulin, alpha 3B, [Score=845, Expect=0.0]; ENSMUSG00000067702, Tuba3a, tubulin, alpha 3A, [Score=845, Expect=0.0]} {Dmel: FBgn0003885, alphaTub84D, alpha-Tubulin at 84D, [Score=837, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [Score=776, Expect=0.0]} {Smed: dd_Smed_v6_10947_0_2, dd_Smed_v6_10947_0_2, [Score=852, Expect=0.0]} {RNA1509_17783} {RNA1310_26095} {RNA815_3971.1}
13. MligTC455_28346 2683 55.89 Mlig455_019110

Neo: -

Age: -

SAXO1 3.369 - 0.773 - 0.877 0.966 0.753 Mlig455_019110 {REF} {Length: 3338} {Human: ENSG00000155875, SAXO1, stabilizer of axonemal microtubules 1, [RH, Score=211, Expect=1e-62]} {Mouse: ENSMUSG00000038570, Saxo2, stabilizer of axonemal microtubules 2, [RH, Score=175, Expect=8e-50]} {Celegans: WBGene00011630, T08G11.3, [RH, Score=77.0, Expect=8e-15]} {Smed: dd_Smed_v6_3695_0_1, dd_Smed_v6_3695_0_1, [RH, Score=476, Expect=4e-166]} {RNA1509_13363, RNA1509_17442, RNA1509_2283, RNA1509_59104} {RNA1310_1293.1, RNA1509_13363, RNA1509_17442, RNA1509_2283, RNA1509_59104} {RNA1509_13363, RNA1509_17442, RNA1509_2283, RNA1509_59104, RNA815_1077}
14. MligTC455_53450 4370 91.04 Mlig455_044396

Neo: -

Age: logFC(26M/2M)=-0.245

AK7 3.27 - 0.718 0.716 - 0.956 0.880 Mlig455_044396 {REF} {Length: 2634} {Pfam: Dpy-30 motif [PF05186.15, score=58.4]; Adenylate kinase [PF00406.24, score=48.5]; AAA domain [PF13207.8, score=29.4]} {Human: ENSG00000140057, AK7, adenylate kinase 7, [RH, Score=650, Expect=0.0]} {Mouse: ENSMUSG00000041323, Ak7, adenylate kinase 7, [RH, Score=679, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00002879, let-754, Adenylate kinase, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_5880_0_1, dd_Smed_v6_5880_0_1, [RH, Score=627, Expect=0.0]} {RNA1509_19178, RNA1509_580} {RNA1310_7753.1, RNA1509_19178, RNA1509_580} {RNA1509_19178, RNA1509_580, RNA815_2574}
15. MligTC455_41200 1715 35.72 Mlig455_069721

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.691

CFAP45 3.252 - - 0.720 0.728 0.955 0.849 Mlig455_069721 {REF} {Length: 2678} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=268.3]} {Human: ENSG00000213085, CFAP45, cilia and flagella associated protein 45, [Score=327, Expect=2e-105]} {Mouse: ENSMUSG00000026546, Cfap45, cilia and flagella associated protein 45, [Score=317, Expect=1e-101]} {Dmel: FBgn0037162, CG11449, [RH, Score=114, Expect=1e-26]} {Smed: dd_Smed_v6_3732_0_1, dd_Smed_v6_3732_0_1, [Score=434, Expect=4e-147]} {RNA1509_11293, RNA1509_455, RNA1509_48510, RNA1509_5508} {RNA1310_7881.1, RNA1509_11293, RNA1509_48510, RNA1509_5508} {RNA1509_11293, RNA1509_48510, RNA1509_5508, RNA815_2376.1}
16. MligTC455_47476 7650 159.38 Mlig455_011139

Neo: -

Age: logFC(26M/2M)=-0.342

RSPH1 3.154 - 0.720 0.748 - 0.967 0.719 Mlig455_011139 {REF} {Length: 1427} {Pfam: MORN repeat [PF02493.22, score=123.5]} {Human: ENSG00000160188, RSPH1, radial spoke head component 1, [RH, Score=256, Expect=6e-84]} {Mouse: ENSMUSG00000024033, Rsph1, radial spoke head 1 homolog (Chlamydomonas), [RH, Score=266, Expect=8e-88]} {Dmel: FBgn0032478, CG5458, [RH, Score=149, Expect=6e-42]} {Celegans: WBGene00002179, jph-1, JunctoPHilin, [Score=59.3, Expect=1e-09]} {Smed: dd_Smed_v6_3321_0_1, dd_Smed_v6_3321_0_1, [RH, Score=306, Expect=6e-104]} {RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1310_22398, RNA1509_10402, RNA1509_5779, RNA1509_6982} {RNA1509_10402, RNA1509_5779, RNA1509_6982, RNA815_10865}
17. MligTC455_14447 1552 32.32 Mlig455_044090

Neo: -

Age: Down-Up-Down

2.705 - - 0.928 - 0.820 0.957 Mlig455_044090 {REF} {Length: 628} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4513) [PF14983.8, score=47.2]} {Smed: dd_Smed_v6_9820_0_1, dd_Smed_v6_9820_0_1, [RH, Score=92.8, Expect=2e-25]} {RNA1509_15130, RNA1509_30396} {RNA1310_35608, RNA1509_15130} {RNA1509_15130, RNA815_26600}
18. MligTC455_37684 4429 92.28 Mlig455_022983

Neo: -

Age: -

DNALI1 2.66 - - 0.803 - 0.899 0.958 Mlig455_022983 {REF} {Length: 1469} {TRANSSPLICED} {Pfam: Axonemal dynein light chain [PF10211.11, score=306.5]; Homeobox associated leucine zipper [PF02183.20, score=19.2]; RIB43A [PF05914.14, score=18.2]} {Human: ENSG00000163879, DNALI1, dynein axonemal light intermediate chain 1, [RH, Score=393, Expect=4e-139]} {Mouse: ENSMUSG00000042707, Dnali1, dynein, axonemal, light intermediate polypeptide 1, [RH, Score=387, Expect=5e-137]} {Dmel: FBgn0037962, CG6971, [RH, Score=283, Expect=3e-96]} {Celegans: WBGene00018307, dyla-1, DYnein Light chain, Axonemal p28 type, [RH, Score=173, Expect=3e-53]} {Smed: dd_Smed_v6_4453_0_1, dd_Smed_v6_4453_0_1, [RH, Score=406, Expect=3e-145]} {RNA1509_10001, RNA1509_17422, RNA1509_28863} {RNA1310_27099, RNA1509_10001, RNA1509_17422, RNA1509_28863} {RNA1509_10001, RNA1509_17422, RNA1509_28863, RNA815_9783}
19. MligTC455_52118 5757 119.94 Mlig455_069122

Neo: -

Age: logFC(26M/2M)=0.892

CFAP58 2.649 - - 0.748 - 0.946 0.955 Mlig455_069122 {REF} {Length: 3136} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=23.0]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=923, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=991, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=1e-40]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1103, Expect=0.0]} {RNA1509_282} {RNA1310_4570, RNA1509_282} {RNA1509_282, RNA815_1528}
20. MligTC455_19338 2431 50.65 Mlig455_022165

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.390

Region-specific R2: 3.133

Region-enriched R2: 2.312/0.00036

2.618 - - 0.799 - 0.839 0.980 Mlig455_022165 {REF} {Length: 1038} {RNA1509_18606, RNA1509_6523} {RNA1310_50737, RNA1509_18606, RNA1509_6523} {RNA1509_18606, RNA1509_6523, RNA815_26880}
21. MligTC455_44365 1412 29.41 Mlig455_002492

Neo: -

Age: logFC(26M/2M)=0.553

MYCBPAP 2.618 - - 0.741 0.922 0.955 - Mlig455_002492 {REF} {Length: 3081} {Pfam: MYCBP-associated protein family [PF14646.8, score=368.3]} {Human: ENSG00000136449, MYCBPAP, MYCBP associated protein, [RH, Score=280, Expect=2e-80]} {Mouse: ENSMUSG00000039110, Mycbpap, MYCBP associated protein, [RH, Score=276, Expect=5e-79]} {Smed: dd_Smed_v6_11993_0_1, dd_Smed_v6_11993_0_1, [RH, Score=323, Expect=3e-97]} {RNA1509_4206} {RNA1310_3498.3} {RNA815_1306}
22. MligTC455_53416 2989 62.26 Mlig455_006517

Neo: -

Age: logFC(26M/2M)=-0.466

ZBTB46 2.613 - 0.760 - 0.893 0.960 - Mlig455_006517 {REF} {Length: 3791} {Pfam: BTB/POZ domain [PF00651.33, score=45.4]; NPH3 family [PF03000.16, score=40.0]} {Human: ENSG00000130584, ZBTB46, zinc finger and BTB domain containing 46, [Score=51.6, Expect=3e-06]; ENSG00000160062, ZBTB8A, zinc finger and BTB domain containing 8A, [Score=51.2, Expect=3e-06]; ENSG00000117153, KLHL12, kelch like family member 12, [Score=49.3, Expect=1e-05]} {Mouse: ENSMUSG00000026455, Klhl12, kelch-like 12, [Score=50.8, Expect=4e-06]; ENSMUSG00000028807, Zbtb8a, zinc finger and BTB domain containing 8a, [Score=49.7, Expect=7e-06]; ENSMUSG00000027583, Zbtb46, zinc finger and BTB domain containing 46, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_8081_0_1, dd_Smed_v6_8081_0_1, [Score=216, Expect=2e-62]} {RNA1509_2983} {RNA1310_18846.1} {RNA815_5532.1}
23. MligTC455_41979 3503 72.98 Mlig455_022271

Neo: -

Age: logFC(26M/2M)=-0.319

2.606 - - - 0.716 0.917 0.973 Mlig455_022271 {REF} {Length: 3465} {Pfam: Domain of unknown function (DUF1330) [PF07045.13, score=28.5]} {Smed: dd_Smed_v6_8243_0_1, dd_Smed_v6_8243_0_1, [Score=117, Expect=5e-31]} {RNA1509_35371, RNA1509_3710, RNA1509_5489} {RNA1310_15598, RNA1509_35371, RNA1509_3710, RNA1509_5489} {RNA1509_35371, RNA1509_3710, RNA1509_5489, RNA815_10198.1}
24. MligTC455_36972 3248 67.67 Mlig455_065599

Neo: -

Age: logFC(26M/2M)=-0.131

KIF9 2.59 - - - 0.783 0.950 0.857 Mlig455_065599 {REF} {Length: 4173} {TRANSSPLICED} {Pfam: Kinesin motor domain [PF00225.25, score=307.7]; Microtubule binding [PF16796.7, score=69.0]} {Human: ENSG00000088727, KIF9, kinesin family member 9, [RH, Score=605, Expect=0.0]} {Mouse: ENSMUSG00000032489, Kif9, kinesin family member 9, [RH, Score=640, Expect=0.0]} {Dmel: FBgn0004380, Klp64D, Kinesin-like protein at 64D, [Score=212, Expect=2e-58]} {Celegans: WBGene00003884, osm-3, Osmotic avoidance abnormal protein 3, [Score=222, Expect=4e-62]} {Smed: dd_Smed_v6_6755_0_1, dd_Smed_v6_6755_0_1, [RH, Score=758, Expect=0.0]} {RNA1509_1683} {RNA1310_5586.1} {RNA815_1778.1}
25. MligTC455_44366 1536 32 Mlig455_002673

Neo: -

Age: logFC(26M/2M)=-0.411

MYCBPAP 2.59 - 0.710 - 0.916 0.964 - Mlig455_002673 {REF} {Length: 3090} {Pfam: MYCBP-associated protein family [PF14646.8, score=366.5]} {Human: ENSG00000136449, MYCBPAP, MYCBP associated protein, [RH, Score=280, Expect=3e-80]} {Mouse: ENSMUSG00000039110, Mycbpap, MYCBP associated protein, [RH, Score=270, Expect=4e-77]} {Smed: dd_Smed_v6_11993_0_1, dd_Smed_v6_11993_0_1, [RH, Score=326, Expect=4e-98]} {RNA1509_4206} {RNA1310_3498.3} {RNA815_1306}
26. MligTC455_53091 542 11.29 Mlig455_061253

Neo: -

Age: -

SPATA1 2.583 - - 0.733 - 0.978 0.872 Mlig455_061253 {REF} {Length: 3411} {Pfam: Spermatogenesis-associated C-terminus [PF15743.7, score=145.3]} {Human: ENSG00000122432, SPATA1, spermatogenesis associated 1, [Score=108, Expect=2e-24]} {Mouse: ENSMUSG00000028188, Spata1, spermatogenesis associated 1, [Score=110, Expect=4e-25]} {Smed: dd_Smed_v6_15381_0_1, dd_Smed_v6_15381_0_1, [RH, Score=174, Expect=1e-46]} {RNA1509_56521} {RNA1310_8534} {RNA815_3401.1}
27. MligTC455_19339 1746 36.37 Mlig455_055775

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.338

Region-specific R2: 3.573

Region-enriched R2: 2.166/0.00065

2.577 - - 0.771 0.845 - 0.961 Mlig455_055775 {REF} {Length: 1701} {TRANSSPLICED} {RNA1509_28058, RNA1509_53885} {RNA1310_50737, RNA1509_28058, RNA1509_53885} {RNA1509_28058, RNA1509_53885, RNA815_26880}
28. MligTC455_49015 2886 60.13 Mlig455_019168

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.204

PPP1R32 2.546 - - - 0.719 0.950 0.877 Mlig455_019168 {REF} {Length: 1846} {TRANSSPLICED} {Pfam: Protein phosphatase 1 regulatory subunit 32 [PF15691.7, score=381.2]} {Human: ENSG00000162148, PPP1R32, protein phosphatase 1 regulatory subunit 32, [RH, Score=130, Expect=5e-33]} {Mouse: ENSMUSG00000035179, Ppp1r32, protein phosphatase 1, regulatory subunit 32, [RH, Score=150, Expect=2e-40]} {Smed: dd_Smed_v6_6404_0_1, dd_Smed_v6_6404_0_1, [RH, Score=263, Expect=2e-83]} {RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1310_15371.1, RNA1509_2656, RNA1509_42026, RNA1509_47496} {RNA1509_2656, RNA1509_42026, RNA1509_47496, RNA815_5915}
29. MligTC455_53683 2280 47.51 Mlig455_008125, Mlig455_008133

Neo: -

Age: -

ERICH6 2.486 - 0.743 0.764 - 0.979 -

Mlig455_008125 {REF} {Length: 2384} {Pfam: FAM194 protein [PF14977.8, score=172.8]; Protein of unknown function (DUF429) [PF04250.15, score=20.3]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [Score=159, Expect=2e-41]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=114, Expect=7e-26]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=229, Expect=3e-66]} {RNA1509_13316} {RNA1310_9580.2} {RNA815_3023.1}

Mlig455_008133 {REF} {Length: 2411} {Pfam: FAM194 protein [PF14977.8, score=172.2]} {Human: ENSG00000163645, ERICH6, glutamate rich 6, [RH, Score=162, Expect=2e-42]} {Mouse: ENSMUSG00000070471, Erich6, glutamate rich 6, [Score=112, Expect=3e-25]} {Smed: dd_Smed_v6_11097_0_1, dd_Smed_v6_11097_0_1, [RH, Score=230, Expect=1e-66]} {RNA1509_15088} {RNA1310_8374} {RNA815_3023.1}
30. MligTC455_16051 3672 76.49 Mlig455_051486

Neo: -

Age: Down-Down-Up

NUDT9 2.477 - 0.720 - 0.806 0.951 - Mlig455_051486 {REF} {Length: 1822} {TRANSSPLICED} {Pfam: NUDIX domain [PF00293.30, score=22.9]} {Human: ENSG00000170502, NUDT9, nudix hydrolase 9, [RH, Score=278, Expect=8e-92]} {Mouse: ENSMUSG00000029310, Nudt9, nudix (nucleoside diphosphate linked moiety X)-type motif 9, [RH, Score=281, Expect=4e-93]} {Dmel: FBgn0036648, CG4098, [RH, Score=258, Expect=1e-84]} {Celegans: WBGene00003583, ndx-6, Putative nudix hydrolase 6, [RH, Score=214, Expect=2e-68]} {Smed: dd_Smed_v6_1143_0_1, dd_Smed_v6_1143_0_1, [RH, Score=293, Expect=1e-98]} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_4802, RNA1509_51897} {RNA1310_32536, RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897} {RNA1509_16712, RNA1509_23680, RNA1509_23855, RNA1509_51897, RNA815_11473.1}
31. MligTC455_20070 2764 57.59 Mlig455_018898, Mlig455_064935

Neo: -

Age: logFC(26M/2M)=-0.311

AXDND1 2.474 - - - 0.764 0.959 0.751

Mlig455_018898 {REF} {Length: 3733} {TRANSSPLICED} {Pfam: Axonemal dynein light chain [PF10211.11, score=41.1]} {Human: ENSG00000162779, AXDND1, axonemal dynein light chain domain containing 1, [RH, Score=406, Expect=5e-124]} {Mouse: ENSMUSG00000026601, Axdnd1, axonemal dynein light chain domain containing 1, [RH, Score=401, Expect=1e-121]} {Smed: dd_Smed_v6_17219_0_1, dd_Smed_v6_17219_0_1, [RH, Score=436, Expect=1e-135]} {RNA1509_4031} {RNA1310_3220.1} {RNA815_882.1}

Mlig455_064935 {REF} {Length: 3676} {TRANSSPLICED} {Pfam: Axonemal dynein light chain [PF10211.11, score=39.8]} {Human: ENSG00000162779, AXDND1, axonemal dynein light chain domain containing 1, [RH, Score=417, Expect=2e-128]} {Mouse: ENSMUSG00000026601, Axdnd1, axonemal dynein light chain domain containing 1, [RH, Score=410, Expect=4e-125]} {Smed: dd_Smed_v6_17219_0_1, dd_Smed_v6_17219_0_1, [RH, Score=440, Expect=3e-137]} {RNA1509_12971, RNA1509_51405} {RNA1310_3220.1, RNA1509_51405} {RNA1509_51405, RNA815_882.1}
32. MligTC455_16370 2203 45.9 Mlig455_030628, Mlig455_031013

Neo: -

Age: logFC(26M/2M)=-0.323

ARMC3 2.473 - - 0.711 - 0.960 0.802

Mlig455_030628 {REF} {Length: 2931} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.4]; Armadillo/beta-catenin-like repeat [PF00514.25, score=81.7]; HEAT repeats [PF13646.8, score=63.8]; HEAT-like repeat [PF13513.8, score=49.3]; V-ATPase subunit H [PF11698.10, score=49.2]; HEAT repeat [PF02985.24, score=38.5]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=29.0]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=496, Expect=2e-162]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=471, Expect=7e-153]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=665, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}

Mlig455_031013 {REF} {Length: 2952} {TRANSSPLICED} {Pfam: Ethylene-responsive protein kinase Le-CTR1 [PF14381.8, score=96.8]; Armadillo/beta-catenin-like repeat [PF00514.25, score=80.8]; HEAT repeats [PF13646.8, score=63.8]; V-ATPase subunit H [PF11698.10, score=50.9]; HEAT-like repeat [PF13513.8, score=48.4]; HEAT repeat [PF02985.24, score=40.7]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=31.6]; Required for nuclear transport of RNA pol II C-terminus 1 [PF10363.11, score=18.7]} {Human: ENSG00000165309, ARMC3, armadillo repeat containing 3, [Score=474, Expect=3e-154]} {Mouse: ENSMUSG00000037683, Armc3, armadillo repeat containing 3, [Score=335, Expect=1e-101]} {Dmel: FBgn0033794, CG13326, [RH, Score=62.8, Expect=1e-09]} {Smed: dd_Smed_v6_9679_0_1, dd_Smed_v6_9679_0_1, [Score=643, Expect=0.0]} {RNA1509_7762} {RNA1310_5967} {RNA815_1775.1}
33. MligTC455_21635 1157 24.11 Mlig455_026396

Neo: -

Age: -

SLC6A5 2.434 - 0.747 0.734 - 0.953 - Mlig455_026396 {REF} {Length: 3636} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=612.2]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=486, Expect=2e-161]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=490, Expect=6e-163]} {Dmel: FBgn0034911, CG5549, [Score=499, Expect=2e-162]} {Celegans: WBGene00004905, snf-6, Sodium-dependent acetylcholine transporter, [RH, Score=374, Expect=2e-119]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [Score=459, Expect=1e-152]} {RNA1509_26562} {RNA1310_4707.2, RNA1509_26562} {RNA1509_26562, RNA815_1349.2}
34. MligTC455_24891 845 17.6 Mlig455_016464

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.290

2.422 - - 0.716 - 0.747 0.959 Mlig455_016464 {REF} {Length: 2447} {RNA1509_20271, RNA1509_46463} {RNA1310_10597.1, RNA1509_20271, RNA1509_46463} {RNA1509_20271, RNA1509_46463, RNA815_3690.1}
35. MligTC455_18481 1416 29.5 Mlig455_061762

Neo: -

Age: Down-Down-Up

Region-enriched R2: 1.816/0.04103

IFT88 1.906 - - - - 0.964 0.942 Mlig455_061762 {REF} {Length: 3149} {Pfam: Tetratricopeptide repeat [PF07719.19, score=111.4]; Tetratricopeptide repeat [PF00515.30, score=99.7]; Tetratricopeptide repeat [PF13424.8, score=98.0]; Tetratricopeptide repeat [PF13181.8, score=76.4]; Tetratricopeptide repeat [PF14559.8, score=73.3]; Tetratricopeptide repeat [PF13174.8, score=71.7]; Tetratricopeptide repeat [PF13432.8, score=71.0]; Tetratricopeptide repeat [PF13428.8, score=70.9]; Tetratricopeptide repeat [PF13176.8, score=61.5]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=56.3]; TPR repeat [PF13414.8, score=50.2]; Tetratricopeptide repeat [PF13371.8, score=40.4]; Tetratricopeptide repeat [PF13374.8, score=31.9]; Tetratricopeptide repeat-like domain [PF09976.11, score=28.6]; Tetratricopeptide repeat [PF13431.8, score=22.0]; MalT-like TPR region [PF17874.3, score=21.7]} {Human: ENSG00000032742, IFT88, intraflagellar transport 88, [RH, Score=867, Expect=0.0]} {Mouse: ENSMUSG00000040040, Ift88, intraflagellar transport 88, [RH, Score=908, Expect=0.0]} {Dmel: FBgn0016919, nompB, no mechanoreceptor potential B, [RH, Score=349, Expect=1e-107]} {Celegans: WBGene00003885, osm-5, OSM-5, [RH, Score=624, Expect=0.0]} {Smed: dd_Smed_v6_5484_0_1, dd_Smed_v6_5484_0_1, [RH, Score=976, Expect=0.0]} {RNA1509_34996, RNA1509_4056} {RNA1310_1829, RNA1509_34996, RNA1509_4056} {RNA1509_34996, RNA1509_4056, RNA815_705}
36. MligTC455_42863 4143 86.31 Mlig455_015957

Neo: -

Age: -

CCDC65 1.902 - - - - 0.961 0.941 Mlig455_015957 {REF} {Length: 1928} {TRANSSPLICED} {Pfam: Sperm tail [PF14772.8, score=82.2]; Sperm tail C-terminal domain [PF14775.8, score=25.0]} {Human: ENSG00000139537, CCDC65, coiled-coil domain containing 65, [RH, Score=401, Expect=3e-135]} {Mouse: ENSMUSG00000003354, Ccdc65, coiled-coil domain containing 65, [RH, Score=420, Expect=1e-142]} {Dmel: FBgn0050259, CG30259, [RH, Score=166, Expect=8e-45]} {Smed: dd_Smed_v6_6152_0_1, dd_Smed_v6_6152_0_1, [RH, Score=525, Expect=0.0]} {RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196} {RNA1310_14593, RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196} {RNA1509_10456, RNA1509_14724, RNA1509_1709, RNA1509_21982, RNA1509_37196, RNA815_5330}
37. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

CCDC39 1.899 - - - - 0.948 0.951 Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
38. MligTC455_38918 3484 72.59 Mlig455_016984

Neo: -

Age: -

SPAG17 1.887 - - - - 0.958 0.929 Mlig455_016984 {REF} {Length: 7773} {Human: ENSG00000155761, SPAG17, sperm associated antigen 17, [Score=555, Expect=8e-162]} {Mouse: ENSMUSG00000027867, Spag17, sperm associated antigen 17, [Score=283, Expect=3e-76]} {Celegans: WBGene00015646, mlt-10, [RH, Score=177, Expect=1e-45]} {Smed: dd_Smed_v6_9301_0_1, dd_Smed_v6_9301_0_1, [Score=543, Expect=8e-159]} {RNA1509_1598} {RNA1310_263.1} {RNA815_1526.1}
39. MligTC455_29450 827 17.23 Mlig455_026424

Neo: -

Age: logFC(26M/2M)=-0.523

LMNTD1 1.845 - - - - 0.972 0.873 Mlig455_026424 {REF} {Length: 3702} {Pfam: Intermediate filament protein [PF00038.23, score=52.8]; Lamin Tail Domain [PF00932.21, score=40.5]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=147, Expect=1e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=142, Expect=7e-36]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.8, Expect=9e-13]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.4, Expect=9e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=228, Expect=1e-62]} {RNA1509_16713, RNA1509_7063} {RNA1310_3989.1, RNA1509_16713, RNA1509_7063} {RNA1509_16713, RNA1509_7063, RNA815_1147.1}
40. MligTC455_51758 3507 73.06 Mlig455_034288, Mlig455_069010

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.314

TTC25 1.84 - - - - 0.954 0.886

Mlig455_034288 {REF} {Length: 2046} {Pfam: Tetratricopeptide repeat [PF07719.19, score=75.1]; Tetratricopeptide repeat [PF13424.8, score=58.6]; Tetratricopeptide repeat [PF00515.30, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=42.5]; Tetratricopeptide repeat [PF13428.8, score=37.4]; Tetratricopeptide repeat [PF13432.8, score=36.7]; Tetratricopeptide repeat [PF14559.8, score=33.8]; TPR repeat [PF13414.8, score=29.6]; Tetratricopeptide repeat [PF13176.8, score=26.9]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=25.5]; Tetratricopeptide repeat [PF13371.8, score=25.3]; Domain of Unknown Function (DUF3856) [PF12968.9, score=22.7]; Tetratricopeptide repeat [PF13431.8, score=21.6]} {Human: ENSG00000204815, TTC25, tetratricopeptide repeat domain 25, [RH, Score=404, Expect=2e-133]} {Mouse: ENSMUSG00000006784, Ttc25, tetratricopeptide repeat domain 25, [RH, Score=423, Expect=3e-141]} {Dmel: FBgn0034692, CG13502, [RH, Score=151, Expect=9e-42]} {Smed: dd_Smed_v6_3933_0_1, dd_Smed_v6_3933_0_1, [RH, Score=530, Expect=0.0]} {RNA1509_32935} {RNA1310_11497} {RNA815_2107.1}

Mlig455_069010 {REF} {Length: 2043} {Pfam: Tetratricopeptide repeat [PF07719.19, score=74.3]; Tetratricopeptide repeat [PF00515.30, score=59.7]; Tetratricopeptide repeat [PF13424.8, score=54.7]; Tetratricopeptide repeat [PF13181.8, score=43.2]; Tetratricopeptide repeat [PF13432.8, score=38.5]; Tetratricopeptide repeat [PF13428.8, score=37.2]; Tetratricopeptide repeat [PF14559.8, score=35.1]; TPR repeat [PF13414.8, score=27.9]; Tetratricopeptide repeat [PF13176.8, score=27.4]; Anaphase-promoting complex, cyclosome, subunit 3 [PF12895.9, score=26.1]; Tetratricopeptide repeat [PF13371.8, score=24.1]; Domain of Unknown Function (DUF3856) [PF12968.9, score=22.4]; Tetratricopeptide repeat [PF13431.8, score=22.2]} {Human: ENSG00000204815, TTC25, tetratricopeptide repeat domain 25, [RH, Score=402, Expect=1e-132]} {Mouse: ENSMUSG00000006784, Ttc25, tetratricopeptide repeat domain 25, [RH, Score=421, Expect=2e-140]} {Dmel: FBgn0034692, CG13502, [RH, Score=150, Expect=3e-41]} {Smed: dd_Smed_v6_3933_0_1, dd_Smed_v6_3933_0_1, [RH, Score=525, Expect=0.0]} {RNA1509_32935, RNA1509_59660} {RNA1310_11497, RNA1509_59660} {RNA1509_59660, RNA815_2107.1}
41. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

LMNTD1 1.839 - - - - 0.968 0.871 Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
42. MligTC455_29452 881 18.34 Mlig455_044747

Neo: -

Age: -

LMNTD1 1.817 - - - - 0.958 0.859 Mlig455_044747 {REF} {Length: 9990} {tRNA: Phe(GAA), score=86.5} {Pfam: Intermediate filament protein [PF00038.23, score=53.6]; Lamin Tail Domain [PF00932.21, score=40.3]; Mechanosensitive ion channel porin domain [PF12795.9, score=20.9]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=146, Expect=3e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=3e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [Score=208, Expect=5e-56]} {RNA1509_20212} {RNA1310_1500.1} {RNA815_1147.1}
43. MligTC455_38105 2374 49.46 Mlig455_015942

Neo: -

Age: logFC(26M/2M)=-0.373

AK9 1.804 - - - - 0.971 0.833 Mlig455_015942 {REF} {Length: 6588} {Pfam: Adenylate kinase [PF00406.24, score=148.4]; AAA domain [PF13207.8, score=69.1]; Domain of unknown function [PF12018.10, score=55.0]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=38.2]; AAA domain [PF13238.8, score=35.5]; YHS domain [PF04945.15, score=34.7]; AAA domain [PF13479.8, score=31.0]; AAA domain [PF13671.8, score=30.4]; AAA domain [PF13401.8, score=23.9]; Hydin Adenylate kinase-like domain [PF17213.5, score=21.5]; RNA helicase [PF00910.24, score=19.7]; AAA domain [PF13521.8, score=19.6]} {Human: ENSG00000155085, AK9, adenylate kinase 9, [RH, Score=1089, Expect=0.0]} {Mouse: ENSMUSG00000091415, Ak9, adenylate kinase 9, [RH, Score=1080, Expect=0.0]} {Dmel: FBgn0283494, Adk2, Adenylate kinase 2, [Score=54.3, Expect=2e-07]} {Celegans: WBGene00009575, F40F8.1, UMP-CMP kinase 2, [Score=58.9, Expect=3e-09]} {Smed: dd_Smed_v6_9617_0_1, dd_Smed_v6_9617_0_1, [RH, Score=863, Expect=0.0]} {RNA1509_1039} {RNA1310_346} {RNA815_505}
44. MligTC455_37308 1663 34.65 Mlig455_040453

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.651

ARRDC1 1.789 - - 0.833 - 0.956 - Mlig455_040453 {REF} {Length: 2316} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.2]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=63.8]} {Human: ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=80.5, Expect=1e-15]; ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=78.6, Expect=7e-15]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=73.6, Expect=2e-13]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=90.9, Expect=1e-19]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.1, Expect=5e-11]} {RNA1509_2401, RNA1509_53571} {RNA1310_27725, RNA1509_53571} {RNA1509_53571, RNA815_11006.1}
45. MligTC455_23589 1204 25.08 Mlig455_013096, Mlig455_013189

Neo: -

Age: -

CNBD1 1.786 - - 0.817 - 0.969 -

Mlig455_013096 {REF} {Length: 1719} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.0]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=213, Expect=2e-63]} {RNA1509_35878} {RNA1310_17903} {RNA815_7217}

Mlig455_013189 {REF} {Length: 1713} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=33.1]} {Human: ENSG00000176571, CNBD1, cyclic nucleotide binding domain containing 1, [RH, Score=117, Expect=5e-30]} {Smed: dd_Smed_v6_14225_0_1, dd_Smed_v6_14225_0_1, [RH, Score=212, Expect=5e-63]} {RNA1509_35878} {RNA1310_17903, RNA1509_35878} {RNA1509_35878, RNA815_7217}
46. MligTC455_49143 772 16.08 Mlig455_021704

Neo: -

Age: -

Region-enriched R2: 1.427/0.03420

1.779 - - - - 0.957 0.822 Mlig455_021704 {REF} {Length: 2489} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=48.8]} {Smed: dd_Smed_v6_13233_0_2, dd_Smed_v6_13233_0_2, [Score=60.1, Expect=4e-09]} {RNA1509_11962} {RNA1310_8951.1, RNA1509_11962}
47. MligTC455_20201 1626 33.88 Mlig455_025333

Neo: -

Age: logFC(26M/2M)=-0.331

TRPA1 1.763 - - - - 0.956 0.807 Mlig455_025333 {REF} {Length: 5343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=283.4]; Ankyrin repeat [PF00023.32, score=234.0]; Ankyrin repeats (many copies) [PF13637.8, score=227.4]; Ankyrin repeat [PF13606.8, score=217.2]; Ankyrin repeats (many copies) [PF13857.8, score=212.6]; Ion transport protein [PF00520.33, score=53.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=368, Expect=5e-107]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=363, Expect=2e-105]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=325, Expect=8e-92]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=2e-150]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [RH, Score=754, Expect=0.0]} {RNA1509_20092} {RNA1310_1173, RNA1509_20092} {RNA1509_20092, RNA815_336}
48. MligTC455_28168 822 17.12 Mlig455_023828

Neo: -

Age: -

1.745 - - - - 0.950 0.795 Mlig455_023828 {REF} {Length: 3967} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [Score=99.0, Expect=5e-22]} {RNA1509_9848} {RNA1310_8221} {RNA815_6368.1}
49. MligTC455_09153 784 16.32 Mlig455_026817

Neo: -

Age: -

1.741 - - - - 0.975 0.766 Mlig455_026817 {REF} {Length: 1131} {TRANSSPLICED} {RNA1509_40542} {RNA1310_5275.2} {RNA815_1594}
50. MligTC455_23150 3195 66.56 Mlig455_009524, Mlig455_009530

Neo: -

Age: -

Region-enriched R2: 3.504/0.00000
Region-enriched R3: 1.656/0.02560

CDK16 1.74 - - - - 0.789 0.951

Mlig455_009524 {REF} {Length: 3287} {Pfam: Protein kinase domain [PF00069.27, score=218.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.2]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [RH, Score=463, Expect=7e-159]; ENSG00000059758, CDK17, cyclin dependent kinase 17, [RH, Score=447, Expect=2e-151]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [RH, Score=464, Expect=2e-158]; ENSMUSG00000020015, Cdk17, cyclin-dependent kinase 17, [RH, Score=449, Expect=2e-152]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=362, Expect=2e-118]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [RH, Score=417, Expect=3e-138]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [RH, Score=449, Expect=6e-151]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}

Mlig455_009530 {REF} {Length: 3384} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000102225, CDK16, cyclin dependent kinase 16, [Score=432, Expect=5e-147]} {Mouse: ENSMUSG00000031065, Cdk16, cyclin-dependent kinase 16, [Score=431, Expect=4e-146]} {Dmel: FBgn0005640, Eip63E, Ecdysone-induced protein 63E, [Score=329, Expect=9e-107]} {Celegans: WBGene00003961, pct-1, Cyclin-dependent kinase 17, [Score=392, Expect=2e-130]} {Smed: dd_Smed_v6_4172_0_4, dd_Smed_v6_4172_0_4, [Score=411, Expect=6e-137]} {RNA1509_23462} {RNA1310_21506} {RNA815_9702}
51. MligTC455_53037 13249 276.01 Mlig455_032646

Neo: -

Age: -

1.737 - - 0.785 - - 0.952 Mlig455_032646 {REF} {Length: 968} {RNA1509_30269, RNA1509_4133, RNA1509_8761} {RNA1310_40499.1, RNA1509_30269, RNA1509_4133, RNA1509_8761} {RNA1509_30269, RNA1509_4133, RNA1509_8761, RNA815_19419.1}
52. MligTC455_53417 2924 60.91 Mlig455_006633

Neo: -

Age: logFC(26M/2M)=-0.635

ZBTB46 1.722 - 0.755 - - 0.967 - Mlig455_006633 {REF} {Length: 4244} {Pfam: BTB/POZ domain [PF00651.33, score=45.4]; NPH3 family [PF03000.16, score=40.0]} {Human: ENSG00000130584, ZBTB46, zinc finger and BTB domain containing 46, [Score=51.6, Expect=3e-06]; ENSG00000160062, ZBTB8A, zinc finger and BTB domain containing 8A, [Score=51.2, Expect=3e-06]; ENSG00000117153, KLHL12, kelch like family member 12, [Score=49.3, Expect=1e-05]} {Mouse: ENSMUSG00000026455, Klhl12, kelch-like 12, [Score=50.8, Expect=4e-06]; ENSMUSG00000028807, Zbtb8a, zinc finger and BTB domain containing 8a, [Score=49.7, Expect=7e-06]; ENSMUSG00000027583, Zbtb46, zinc finger and BTB domain containing 46, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_8081_0_1, dd_Smed_v6_8081_0_1, [Score=216, Expect=2e-62]} {RNA1509_2983} {RNA1310_20884} {RNA815_5532.1}
53. MligTC455_35567 1282 26.72 Mlig455_021647

Neo: -

Age: -

CFAP44 1.708 - 0.753 - - 0.955 - Mlig455_021647 {REF} {Length: 728} {Human: ENSG00000206530, CFAP44, cilia and flagella associated protein 44, [Score=56.2, Expect=5e-10]} {Smed: dd_Smed_v6_8760_0_1, dd_Smed_v6_8760_0_1, [Score=67.4, Expect=2e-14]} {RNA1509_43550} {RNA1310_10626} {RNA815_87.1}
54. MligTC455_39941 9459 197.06 Mlig455_063449, Mlig455_063484

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.626

1.703 - - 0.733 - - 0.970

Mlig455_063449 {REF} {Length: 721} {RNA1509_60047} {RNA1310_34704} {RNA815_21539.1}

Mlig455_063484 {REF} {Length: 862} {RNA1509_60047} {RNA1310_34704} {RNA815_21539.1}
55. MligTC455_45949 4322 90.03 Mlig455_003487

Neo: -

Age: logFC(26M/2M)=-0.316

MNS1 1.689 - 0.727 - - 0.962 - Mlig455_003487 {REF} {Length: 2175} {TRANSSPLICED} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=239.7]} {Human: ENSG00000138587, MNS1, meiosis specific nuclear structural 1, [RH, Score=312, Expect=9e-101]} {Mouse: ENSMUSG00000032221, Mns1, meiosis-specific nuclear structural protein 1, [RH, Score=338, Expect=5e-111]} {Smed: dd_Smed_v6_4463_0_1, dd_Smed_v6_4463_0_1, [RH, Score=380, Expect=2e-127]} {RNA1509_17543, RNA1509_30026, RNA1509_43231, RNA1509_5133, RNA1509_8697} {RNA1310_11484, RNA1509_17543, RNA1509_30026, RNA1509_43231, RNA1509_5133, RNA1509_8697} {RNA1509_17543, RNA1509_30026, RNA1509_43231, RNA1509_5133, RNA1509_8697, RNA815_4005}
56. MligTC455_18605 1372 28.59 Mlig455_030381

Neo: -

Age: logFC(26M/2M)=-0.360

1.683 - - 0.720 - - 0.963 Mlig455_030381 {REF} {Length: 846} {Pfam: Family of unknown function (DUF5582) [PF17819.3, score=54.5]} {Mouse: ENSMUSG00000022798, 4930435E12Rik, RIKEN cDNA 4930435E12 gene, [RH, Score=59.3, Expect=4e-11]} {RNA1509_10400, RNA1509_45977} {RNA1310_50669.1, RNA1509_10400, RNA1509_45977} {RNA1509_10400, RNA1509_45977, RNA815_25237}
57. MligTC455_25217 983 20.49 Mlig455_014480

Neo: -

Age: logFC(26M/2M)=-0.277

FHAD1 1.674 - - 0.707 - 0.967 - Mlig455_014480 {REF} {Length: 4999} {TRANSSPLICED} {Pfam: FHA domain [PF00498.28, score=39.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=24.9]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [RH, Score=215, Expect=9e-56]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [RH, Score=182, Expect=1e-45]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [RH, Score=182, Expect=1e-45]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=346, Expect=1e-98]} {RNA1509_3924} {RNA1310_1575.2} {RNA815_2279}
58. MligTC455_16285 2682 55.88 Mlig455_020319

Neo: -

Age: Down-Up-Up

TMEM107 0.988 - - - - 0.988 - Mlig455_020319 {REF} {Length: 920} {Pfam: Transmembrane protein [PF14995.8, score=118.5]} {Human: ENSG00000179029, TMEM107, transmembrane protein 107, [RH, Score=127, Expect=1e-37]} {Mouse: ENSMUSG00000020895, Tmem107, transmembrane protein 107, [RH, Score=123, Expect=2e-36]} {Smed: dd_Smed_v6_13204_0_4, dd_Smed_v6_13204_0_4, [RH, Score=97.4, Expect=2e-26]} {RNA1509_30443} {RNA1310_40623} {RNA815_15713}
59. MligTC455_34365 761 15.86 Mlig455_045898

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-1.155

0.98 - - - - 0.980 - Mlig455_045898 {REF} {Length: 1534} {RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1310_33460, RNA1509_18388, RNA1509_36026, RNA1509_43852} {RNA1509_18388, RNA1509_36026, RNA1509_43852, RNA815_35266}
60. MligTC455_53502 2219 46.22 Mlig455_044502

Neo: -

Age: -

Region-enriched R4: 1.100/0.01013

IFT22 0.968 - - - - - 0.968 Mlig455_044502 {REF} {Length: 926} {Pfam: Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=42.7]; Ras family [PF00071.24, score=36.8]; ADP-ribosylation factor family [PF00025.23, score=35.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.4]} {Human: ENSG00000128581, IFT22, intraflagellar transport 22, [RH, Score=148, Expect=5e-45]} {Mouse: ENSMUSG00000007987, Ift22, intraflagellar transport 22, [RH, Score=139, Expect=8e-42]} {Celegans: WBGene00012132, ifta-2, Intraflagellar transport associated protein 2, [RH, Score=95.9, Expect=2e-24]} {Smed: dd_Smed_v6_11176_0_1, dd_Smed_v6_11176_0_1, [RH, Score=213, Expect=5e-71]} {RNA1509_10351, RNA1509_35028, RNA1509_53245} {RNA1310_41419, RNA1509_10351, RNA1509_35028, RNA1509_53245} {RNA1509_10351, RNA1509_35028, RNA1509_53245, RNA815_20100}
61. MligTC455_40052 513 10.68 Mlig455_035856

Neo: -

Age: -

0.964 - - - - 0.964 - Mlig455_035856 {REF} {Length: 3180} {TRANSSPLICED} {Smed: dd_Smed_v6_14291_0_1, dd_Smed_v6_14291_0_1, [RH, Score=221, Expect=3e-61]} {RNA1509_6964} {RNA1310_5805} {RNA815_1720}
62. MligTC455_46892 510 10.61 Mlig455_024306, Mlig455_024361

Neo: -

Age: -

RAB8B 0.958 - - - - 0.958 -

Mlig455_024306 {REF} {Length: 1532} {Pfam: Ras family [PF00071.24, score=212.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=118.0]; ADP-ribosylation factor family [PF00025.23, score=77.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=27.4]; 50S ribosome-binding GTPase [PF01926.25, score=23.8]; Gtr1/RagA G protein conserved region [PF04670.14, score=23.5]; RsgA GTPase [PF03193.18, score=22.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=18.9]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=257, Expect=4e-87]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=254, Expect=1e-85]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=256, Expect=6e-87]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=254, Expect=4e-86]} {Dmel: FBgn0262518, Rab8, [Score=245, Expect=1e-82]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=248, Expect=8e-84]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=251, Expect=2e-85]} {RNA1509_53476} {RNA1310_24855} {RNA815_9980.1}

Mlig455_024361 {REF} {Length: 1538} {Pfam: Ras family [PF00071.24, score=212.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=118.0]; ADP-ribosylation factor family [PF00025.23, score=77.6]; Elongation factor Tu GTP binding domain [PF00009.29, score=27.4]; 50S ribosome-binding GTPase [PF01926.25, score=23.8]; Gtr1/RagA G protein conserved region [PF04670.14, score=23.5]; RsgA GTPase [PF03193.18, score=22.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=18.9]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [Score=257, Expect=4e-87]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [Score=254, Expect=1e-85]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [Score=256, Expect=6e-87]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [Score=254, Expect=4e-86]} {Dmel: FBgn0262518, Rab8, [Score=245, Expect=1e-82]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [Score=248, Expect=8e-84]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=251, Expect=2e-85]} {RNA1509_53476} {RNA1310_24855, RNA1509_53476} {RNA1509_53476, RNA815_9980.1}
63. MligTC455_46850 265 5.52 Mlig455_005746

Neo: -

Age: -

Region-enriched R4: 2.659/0.01708

0.957 - - - - 0.957 - Mlig455_005746 {REF} {Length: 3392} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=84.7, Expect=3e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=68.9, Expect=1e-11]} {RNA1509_46369, RNA1509_7522} {RNA1310_3662, RNA1509_46369, RNA1509_7522} {RNA1509_46369, RNA1509_7522, RNA815_5689}
64. MligTC455_45702 777 16.19 Mlig455_008333

Neo: -

Age: logFC(26M/2M)=-0.568

ADAM12 0.956 - - - - 0.956 - Mlig455_008333 {REF} {Length: 3197} {Pfam: Reprolysin (M12B) family zinc metalloprotease [PF01421.21, score=123.0]; Disintegrin [PF00200.25, score=72.7]; Metallo-peptidase family M12 [PF13688.8, score=51.8]; Metallo-peptidase family M12B Reprolysin-like [PF13574.8, score=42.1]; ADAM cysteine-rich [PF08516.14, score=40.6]; Metallo-peptidase family M12B Reprolysin-like [PF13582.8, score=38.9]; Metallo-peptidase family M12B Reprolysin-like [PF13583.8, score=38.3]} {Human: ENSG00000148848, ADAM12, ADAM metallopeptidase domain 12, [Score=236, Expect=1e-64]; ENSG00000168615, ADAM9, ADAM metallopeptidase domain 9, [Score=231, Expect=3e-64]; ENSG00000149451, ADAM33, ADAM metallopeptidase domain 33, [Score=229, Expect=4e-63]} {Mouse: ENSMUSG00000054555, Adam12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), [Score=228, Expect=2e-62]; ENSMUSG00000014725, Adam28, a disintegrin and metallopeptidase domain 28, [Score=226, Expect=5e-62]; ENSMUSG00000031555, Adam9, a disintegrin and metallopeptidase domain 9 (meltrin gamma), [Score=225, Expect=1e-61]} {Dmel: FBgn0265140, Meltrin, [Score=250, Expect=7e-70]} {Celegans: WBGene00000074, adm-2, ADAM (Disintegrin plus metalloprotease) family, [Score=216, Expect=2e-58]} {Smed: dd_Smed_v6_5143_0_1, dd_Smed_v6_5143_0_1, [Score=231, Expect=6e-63]} {RNA1509_7145} {RNA1310_4464.1, RNA1509_7145} {RNA1509_7145, RNA815_1440.1}
65. MligTC455_54146 1239 25.82 Mlig455_049378

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.386

DRC7 0.955 - - - - 0.955 - Mlig455_049378 {REF} {Length: 3401} {Pfam: Transglutaminase-like superfamily [PF01841.21, score=19.6]} {Human: ENSG00000159625, DRC7, dynein regulatory complex subunit 7, [RH, Score=736, Expect=0.0]} {Mouse: ENSMUSG00000031786, Drc7, dynein regulatory complex subunit 7, [RH, Score=728, Expect=0.0]} {Dmel: FBgn0083946, lobo, lost boys, [RH, Score=280, Expect=4e-80]} {Smed: dd_Smed_v6_12588_0_1, dd_Smed_v6_12588_0_1, [RH, Score=708, Expect=0.0]} {RNA1509_1230} {RNA1310_4483} {RNA815_1294}
66. MligTC455_27837 39 0.81 Mlig455_007266

Neo: -

Age: Down-Up-Down

0.954 - - - - 0.954 - Mlig455_007266 {REF} {Length: 5168} {Pfam: Integrase zinc binding domain [PF17921.3, score=71.6]; Integrase core domain [PF00665.28, score=50.6]; DDE superfamily endonuclease [PF13358.8, score=21.8]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=208, Expect=2e-61]} {RNA1509_20493} {RNA1310_131.1} {RNA815_52.1}
67. MligTC455_38958 335 6.98 Mlig455_068315

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_068315 {REF} {Length: 2665} {Pfam: EF-hand domain [PF13405.8, score=31.1]; EF-hand domain pair [PF13499.8, score=27.3]; EF hand [PF00036.34, score=22.7]} {Mouse: ENSMUSG00000030321, Efcab12, EF-hand calcium binding domain 12, [RH, Score=65.1, Expect=2e-10]} {Smed: dd_Smed_v6_10608_0_1, dd_Smed_v6_10608_0_1, [RH, Score=57.8, Expect=7e-10]} {RNA1509_20232} {RNA1310_17116} {RNA815_14272}
68. MligTC455_53211 1358 28.3 Mlig455_040065, Mlig455_040091

Neo: -

Age: logFC(26M/2M)=-0.362

Region-enriched R4: 1.888/0.01442

0.954 - - - - 0.954 -

Mlig455_040065 {REF} {Length: 3189} {RNA1509_49542, RNA1509_9168} {RNA1310_8796.1, RNA1509_49542, RNA1509_9168} {RNA1509_49542, RNA1509_9168, RNA815_3100}

Mlig455_040091 {REF} {Length: 2759} {RNA1509_39791, RNA1509_9168} {RNA1310_8796.1, RNA1509_39791} {RNA1509_39791, RNA815_3100}
69. MligTC455_41960 6508 135.58 Mlig455_064540

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

Region-enriched R2: 2.143/0.00375
Region-enriched R8: 2.136/0.00048
Region-enriched R7: 1.650/0.01262

CALM2 0.952 - - - - - 0.952 Mlig455_064540 {REF} {Length: 3428} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=120.0]; EF-hand domain pair [PF13833.8, score=76.2]; EF-hand domain [PF08976.13, score=69.6]; EF hand [PF00036.34, score=67.4]; EF-hand domain [PF13405.8, score=64.4]; EF-hand domain [PF14658.8, score=35.9]; Family of unknown function (DUF5580) [PF17743.3, score=33.5]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=62.8, Expect=2e-10]; ENSG00000178372, CALML5, calmodulin like 5, [Score=60.5, Expect=5e-10]; ENSG00000160014, CALM3, calmodulin 3, [Score=60.1, Expect=7e-10]; ENSG00000198668, CALM1, calmodulin 1, [Score=60.1, Expect=7e-10]; ENSG00000175544, CABP4, calcium binding protein 4, [Score=59.7, Expect=8e-09]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=108, Expect=3e-23]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=58.9, Expect=9e-10]} {Celegans: WBGene00006861, cal-5, CALmodulin related genes, [Score=61.2, Expect=1e-10]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [RH, Score=168, Expect=3e-44]} {RNA1509_9023} {RNA1310_4944.1} {RNA815_7678}
70. MligTC455_24898 242 5.04 Mlig455_049807

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.253

0.951 - - - - 0.951 - Mlig455_049807 {REF} {Length: 2440} {RNA1509_20271} {RNA1310_10597.1} {RNA815_3690.1}
71. MligTC455_29904 179 3.73 Mlig455_047055

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.696

MAP3K4 0.951 - - - - 0.951 - Mlig455_047055 {REF} {Length: 3991} {Pfam: Protein kinase domain [PF00069.27, score=316.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=241.4]; Fungal protein kinase [PF17667.3, score=53.7]; ABC1 atypical kinase-like domain [PF03109.18, score=35.6]; Phosphotransferase enzyme family [PF01636.25, score=34.3]; Ankyrin repeat [PF13606.8, score=24.2]; Kinase-like [PF14531.8, score=24.2]; Ankyrin repeats (3 copies) [PF12796.9, score=23.2]; Ternary complex associated domain 9 [PF19974.1, score=22.5]; Seadornavirus VP7 [PF07387.13, score=20.7]; Ankyrin repeat [PF00023.32, score=20.0]; Ankyrin repeats (many copies) [PF13857.8, score=19.9]; Choline/ethanolamine kinase [PF01633.22, score=18.5]} {Human: ENSG00000085511, MAP3K4, mitogen-activated protein kinase kinase kinase 4, [Score=132, Expect=5e-31]; ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=127, Expect=2e-30]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=132, Expect=5e-32]; ENSMUSG00000014426, Map3k4, mitogen-activated protein kinase kinase kinase 4, [Score=128, Expect=7e-30]} {Dmel: FBgn0024329, Mekk1, [Score=124, Expect=2e-28]} {Celegans: WBGene00003472, mtk-1, MTK1/MEKK4 homolog, [Score=129, Expect=2e-30]} {Smed: dd_Smed_v6_9379_0_2, dd_Smed_v6_9379_0_2, [Score=121, Expect=2e-28]} {RNA1509_39395} {RNA1310_23280} {RNA815_6977.2}
72. MligTC455_30008 1648 34.33 Mlig455_036850, Mlig455_052985

Neo: -

Age: logFC(26M/2M)=0.507

CALM2 0.951 - - - - - 0.951

Mlig455_036850 {REF} {Length: 1837} {Pfam: EF-hand domain pair [PF13499.8, score=72.9]; EF hand [PF00036.34, score=61.6]; EF-hand domain [PF13405.8, score=58.2]; EF hand [PF13202.8, score=32.1]; EF-hand domain pair [PF13833.8, score=29.6]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=21.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=72.8, Expect=6e-15]; ENSG00000198668, CALM1, calmodulin 1, [Score=71.6, Expect=7e-15]; ENSG00000160014, CALM3, calmodulin 3, [Score=71.2, Expect=9e-15]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=73.2, Expect=4e-15]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=72.0, Expect=3e-15]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=71.2, Expect=6e-15]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=71.2, Expect=6e-15]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=71.2, Expect=5e-15]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=70.9, Expect=4e-15]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=70.9, Expect=4e-15]} {RNA1509_33558} {RNA1310_22016.1} {RNA815_9163.1}

Mlig455_052985 {REF} {Length: 1692} {Pfam: EF-hand domain pair [PF13499.8, score=68.3]; EF hand [PF00036.34, score=59.5]; EF-hand domain [PF13405.8, score=57.3]; EF hand [PF13202.8, score=30.0]; EF-hand domain pair [PF13833.8, score=26.2]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=21.0]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=70.5, Expect=4e-14]; ENSG00000198668, CALM1, calmodulin 1, [Score=69.3, Expect=5e-14]; ENSG00000160014, CALM3, calmodulin 3, [Score=69.3, Expect=5e-14]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=71.2, Expect=2e-14]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=69.7, Expect=2e-14]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=69.3, Expect=4e-14]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=69.3, Expect=4e-14]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=68.9, Expect=3e-14]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=68.9, Expect=3e-14]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=68.9, Expect=2e-14]} {RNA1509_33558, RNA1509_35943} {RNA1310_22016.1, RNA1509_33558, RNA1509_35943} {RNA1509_33558, RNA1509_35943, RNA815_9163.1}
73. MligTC455_32112 1724 35.92 Mlig455_067479, Mlig455_067487

Neo: -

Age: -

SYT14 0.951 - - - - 0.951 -

Mlig455_067479 {REF} {Length: 2410} {Pfam: C2 domain [PF00168.32, score=47.3]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [Score=128, Expect=5e-31]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [Score=130, Expect=3e-31]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [Score=114, Expect=2e-26]} {Smed: dd_Smed_v6_9164_0_3, dd_Smed_v6_9164_0_3, [Score=80.1, Expect=8e-16]} {RNA1509_11231} {RNA1310_10515.1} {RNA815_5645}

Mlig455_067487 {REF} {Length: 2567} {Pfam: C2 domain [PF00168.32, score=65.1]} {Human: ENSG00000143469, SYT14, synaptotagmin 14, [RH, Score=231, Expect=2e-67]} {Mouse: ENSMUSG00000016200, Syt14, synaptotagmin XIV, [RH, Score=229, Expect=2e-64]} {Dmel: FBgn0261086, Syt14, Synaptotagmin 14, [RH, Score=219, Expect=6e-62]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=73.9, Expect=1e-13]} {Smed: dd_Smed_v6_9548_0_2, dd_Smed_v6_9548_0_2, [RH, Score=178, Expect=2e-49]} {RNA1509_11231} {RNA1310_10515.1} {RNA815_5645}
74. MligTC455_47383 2319 48.32 Mlig455_049031, Mlig455_063739

Neo: -

Age: logFC(26M/2M)=1.164

0.951 - - - - 0.951 -

Mlig455_049031 {REF} {Length: 1477} {RNA1509_16827} {RNA1310_19392.1} {RNA815_20667}

Mlig455_063739 {REF} {Length: 5644} {RNA1509_9711} {RNA1310_19392.1} {RNA815_20667}
75. MligTC455_49821 2230 46.46 Mlig455_008776, Mlig455_008813

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=2.472

0.951 - - - - - 0.951

Mlig455_008776 {REF} {Length: 834} {RNA1509_24401} {RNA1310_40742} {RNA815_19348}

Mlig455_008813 {REF} {Length: 935} {RNA1509_24401, RNA1509_44113} {RNA1310_40742, RNA1509_24401, RNA1509_44113} {RNA1509_24401, RNA1509_44113, RNA815_19348}
76. MligTC455_45394 1156 24.08 Mlig455_009723

Neo: -

Age: -

DLC1 0.95 - - 0.950 - - - Mlig455_009723 {REF} {Length: 4644} {Pfam: RhoGAP domain [PF00620.29, score=114.0]; START domain [PF01852.21, score=58.1]} {Human: ENSG00000285265, DLC1, DLC1 Rho GTPase activating protein, [Score=337, Expect=8e-99]; ENSG00000164741, DLC1, DLC1 Rho GTPase activating protein, [Score=337, Expect=1e-96]; ENSG00000133121, STARD13, StAR related lipid transfer domain containing 13, [Score=326, Expect=3e-95]} {Mouse: ENSMUSG00000016128, Stard13, StAR-related lipid transfer (START) domain containing 13, [Score=333, Expect=7e-98]; ENSMUSG00000031523, Dlc1, deleted in liver cancer 1, [Score=331, Expect=1e-94]} {Dmel: FBgn0285955, cv-c, crossveinless c, [Score=277, Expect=4e-78]} {Celegans: WBGene00001559, gei-1, GEX Interacting protein, [Score=196, Expect=6e-51]} {Smed: dd_Smed_v6_9530_0_2, dd_Smed_v6_9530_0_2, [Score=305, Expect=1e-88]} {RNA1509_22275, RNA1509_9216} {RNA1310_3779, RNA1509_22275} {RNA1509_22275, RNA815_16531}

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