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Results for MligTC455_27545

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27545 130 2.71 Mlig455_042355

Neo: -

Age: logFC(26M/2M)=-0.989

 KREMEN1 Mlig455_042355 {REF} {Length: 5033} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=63.6]; Ankyrin repeats (many copies) [PF13637.8, score=52.3]; WSC domain [PF01822.21, score=42.5]; Ankyrin repeat [PF13606.8, score=38.6]; Ankyrin repeat [PF00023.32, score=30.8]; Ankyrin repeats (many copies) [PF13857.8, score=26.9]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=50.1, Expect=3e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=52.8, Expect=6e-08]} {RNA1509_48795} {RNA1310_1739} {RNA815_2547.1}

Cumulative graph for MligTC455_27545

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -4.227 2.338 0.99960 1.00000
RegionR2 3.695 2.338 0.05228 0.27346
RegionR3 2.711 2.338 0.05025 0.39217
RegionR4 1.337 2.338 0.37716 0.70125
RegionR5 0.439 2.338 0.65095 1.00000
RegionR6 1.236 2.338 0.43255 0.99563
RegionR7 -1.056 2.338 0.93915 1.00000
RegionR8 -4.135 2.338 0.99967 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.129 2.338 0.99990 1.00000
RegenerationR2 -3.147 2.338 0.01607 0.20847
RegenerationR3 -3.107 2.338 0.02781 0.29985
RegenerationR4 -2.212 2.338 0.13386 0.55244
RegenerationR5 -2.338 2.338 0.09423 0.47031
RegenerationR6 -1.678 2.338 0.24578 0.59381
RegenerationBL -3.239 2.338 0.99949 1.00000
RegenerationTP 4.006 2.338 0.09753 0.48857


Genes with expression patterns similar to MligTC455_27545

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27545 130 2.71 Mlig455_042355

Neo: -

Age: logFC(26M/2M)=-0.989

 KREMEN1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_042355 {REF} {Length: 5033} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=63.6]; Ankyrin repeats (many copies) [PF13637.8, score=52.3]; WSC domain [PF01822.21, score=42.5]; Ankyrin repeat [PF13606.8, score=38.6]; Ankyrin repeat [PF00023.32, score=30.8]; Ankyrin repeats (many copies) [PF13857.8, score=26.9]} {Human: ENSG00000183762, KREMEN1, kringle containing transmembrane protein 1, [Score=50.1, Expect=3e-07]} {Mouse: ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=52.8, Expect=6e-08]} {RNA1509_48795} {RNA1310_1739} {RNA815_2547.1}
2. MligTC455_12144 296 6.18 Mlig455_020300, Mlig455_020357

Neo: -

Age: -

 1.816 - - 0.951 - - 0.865

Mlig455_020300 {REF} {Length: 1436} {RNA1310_11315} {RNA815_39851}

Mlig455_020357 {REF} {Length: 1334} {RNA1310_11315} {RNA815_39851}
3. MligTC455_37988 67 1.41 Mlig455_008561

Neo: -

Age: -

Region-enriched R2: 8.988/0.00000

 1.759 - 0.787 - - 0.972 - Mlig455_008561 {REF} {Length: 3146} {Pfam: EF-hand domain pair [PF13499.8, score=36.5]; EF-hand domain [PF13405.8, score=31.2]; EF hand [PF00036.34, score=29.3]; EF-hand domain pair [PF13833.8, score=20.4]; EF hand [PF13202.8, score=19.4]} {Smed: dd_Smed_v6_1010_0_1, dd_Smed_v6_1010_0_1, [Score=104, Expect=1e-26]} {RNA1310_31713.1} {RNA815_36423}
4. MligTC455_31771 49 1.02 Mlig455_026245

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.686

 TRIM2 1.71 - - 0.759 - 0.951 - Mlig455_026245 {REF} {Length: 1670} {Pfam: NHL repeat [PF01436.23, score=31.4]} {Human: ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=57.0, Expect=5e-08]; ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=55.1, Expect=2e-07]} {Mouse: ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=57.0, Expect=3e-08]; ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=55.1, Expect=1e-07]} {RNA1509_15622} {RNA1310_14145.1} {RNA815_3900.1}
5. MligTC455_29604 264 5.49 Mlig455_070200

Neo: -

Age: Down-Up-Down

 1.674 - 0.715 - - 0.959 - Mlig455_070200 {REF} {Length: 1448} {Pfam: Dynein light chain type 1 [PF01221.20, score=60.5]; EF-hand domain pair [PF13499.8, score=26.1]; EF hand [PF00036.34, score=24.6]} {Smed: dd_Smed_v6_6707_0_3, dd_Smed_v6_6707_0_3, [Score=127, Expect=1e-37]} {RNA1509_53012} {RNA1310_43825} {RNA815_11614}
6. MligTC455_51189 50 1.04 Mlig455_009762

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.901

 ETV1 1.663 - - - - 0.707 0.956 Mlig455_009762 {REF} {Length: 2915} {Pfam: Ets-domain [PF00178.24, score=116.1]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.9]} {Human: ENSG00000006468, ETV1, ETS variant 1, [RH, Score=196, Expect=6e-55]; ENSG00000244405, ETV5, ETS variant 5, [RH, Score=195, Expect=3e-54]; ENSG00000175832, ETV4, ETS variant 4, [RH, Score=193, Expect=5e-54]} {Mouse: ENSMUSG00000013089, Etv5, ets variant 5, [RH, Score=196, Expect=1e-54]; ENSMUSG00000004151, Etv1, ets variant 1, [RH, Score=195, Expect=5e-55]; ENSMUSG00000017724, Etv4, ets variant 4, [RH, Score=193, Expect=6e-54]} {Dmel: FBgn0039225, Ets96B, [RH, Score=186, Expect=3e-50]} {Celegans: WBGene00016600, ets-5, ETS class transcription factor, [Score=121, Expect=2e-31]} {Smed: dd_Smed_v6_14712_0_1, dd_Smed_v6_14712_0_1, [RH, Score=169, Expect=7e-46]} {RNA1310_33762} {RNA815_60843}
7. MligTC455_54086 101 2.11 Mlig455_006583, Mlig455_006693, Mlig455_006744

Neo: -

Age: -

 CACNA2D1, CACNA2D2 0.991 - - - - 0.991 -

Mlig455_006583 {REF} {Length: 4206} {Pfam: VWA N-terminal [PF08399.13, score=65.5]; Cache domain [PF02743.20, score=54.1]; von Willebrand factor type A domain [PF13519.8, score=35.8]; von Willebrand factor type A domain [PF00092.30, score=33.2]; von Willebrand factor type A domain [PF13768.8, score=26.9]} {Human: ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=169, Expect=5e-42]; ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=168, Expect=1e-41]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=164, Expect=2e-40]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=171, Expect=1e-42]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=169, Expect=3e-42]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=166, Expect=4e-41]} {Dmel: FBgn0028863, CG4587, [Score=146, Expect=5e-35]} {Celegans: WBGene00007041, tag-180, [Score=98.6, Expect=1e-20]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [RH, Score=1425, Expect=0.0]} {RNA1509_47212} {RNA1310_2302} {RNA815_5037}

Mlig455_006693 {REF} {Length: 4381} {Pfam: VWA N-terminal [PF08399.13, score=64.3]; Cache domain [PF02743.20, score=55.6]; von Willebrand factor type A domain [PF13519.8, score=35.8]; von Willebrand factor type A domain [PF00092.30, score=33.2]; von Willebrand factor type A domain [PF13768.8, score=26.9]} {Human: ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=169, Expect=8e-42]; ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=169, Expect=5e-42]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=166, Expect=8e-41]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=171, Expect=7e-43]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=169, Expect=5e-42]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=167, Expect=2e-41]} {Dmel: FBgn0028863, CG4587, [Score=146, Expect=4e-35]} {Celegans: WBGene00007041, tag-180, [Score=98.6, Expect=2e-20]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [RH, Score=1422, Expect=0.0]} {RNA1509_47212} {RNA1310_2302, RNA1509_47212} {RNA1509_47212, RNA815_5037}

Mlig455_006744 {REF} {Length: 4200} {Pfam: VWA N-terminal [PF08399.13, score=65.5]; Cache domain [PF02743.20, score=54.1]; von Willebrand factor type A domain [PF13519.8, score=35.8]; von Willebrand factor type A domain [PF00092.30, score=33.2]; von Willebrand factor type A domain [PF13768.8, score=26.9]} {Human: ENSG00000007402, CACNA2D2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, [Score=169, Expect=6e-42]; ENSG00000153956, CACNA2D1, calcium voltage-gated channel auxiliary subunit alpha2delta 1, [Score=168, Expect=1e-41]; ENSG00000157445, CACNA2D3, calcium voltage-gated channel auxiliary subunit alpha2delta 3, [Score=164, Expect=2e-40]} {Mouse: ENSMUSG00000010066, Cacna2d2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, [Score=171, Expect=2e-42]; ENSMUSG00000040118, Cacna2d1, calcium channel, voltage-dependent, alpha2/delta subunit 1, [Score=169, Expect=3e-42]; ENSMUSG00000021991, Cacna2d3, calcium channel, voltage-dependent, alpha2/delta subunit 3, [Score=166, Expect=4e-41]} {Dmel: FBgn0028863, CG4587, [Score=146, Expect=5e-35]} {Celegans: WBGene00007041, tag-180, [Score=98.6, Expect=1e-20]} {Smed: dd_Smed_v6_19048_0_1, dd_Smed_v6_19048_0_1, [RH, Score=1425, Expect=0.0]} {RNA1509_47212} {RNA1310_2302} {RNA815_5037}
8. MligTC455_26413 528 11.01 Mlig455_070891

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.372

 EPS8 0.986 - - - - 0.986 - Mlig455_070891 {REF} {Length: 3874} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=22.5]; Variant SH3 domain [PF07653.19, score=20.3]} {Human: ENSG00000151491, EPS8, epidermal growth factor receptor pathway substrate 8, [RH, Score=145, Expect=8e-37]} {Mouse: ENSMUSG00000015766, Eps8, epidermal growth factor receptor pathway substrate 8, [Score=154, Expect=3e-40]} {Dmel: FBgn0029095, aru, arouser, [RH, Score=140, Expect=4e-35]} {Celegans: WBGene00001330, eps-8, EPS (Human endocytosis) related; Epidermal growth factor receptor pathway substrate 8 splice variant A, [Score=204, Expect=4e-57]} {Smed: dd_Smed_v6_8993_0_1, dd_Smed_v6_8993_0_1, [RH, Score=74.3, Expect=6e-14]} {RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172} {RNA1310_7150.1, RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172} {RNA1509_27030, RNA1509_45513, RNA1509_55389, RNA1509_59954, RNA1509_7172, RNA815_2475.1}
9. MligTC455_31806 38 0.8 Mlig455_026267

Neo: -

Age: -

 TRIM2 0.985 - - - - 0.985 - Mlig455_026267 {REF} {Length: 1708} {TRANSSPLICED} {Pfam: NHL repeat [PF01436.23, score=31.3]} {Human: ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=56.6, Expect=6e-08]; ENSG00000110171, TRIM3, tripartite motif containing 3, [Score=54.7, Expect=2e-07]} {Mouse: ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=56.6, Expect=5e-08]; ENSMUSG00000036989, Trim3, tripartite motif-containing 3, [Score=54.7, Expect=2e-07]} {RNA1509_15622} {RNA1310_14145.1} {RNA815_3900.1}
10. MligTC455_27031 33 0.69 Mlig455_055855

Neo: -

Age: -

 MTMR14 0.974 - - - - 0.974 - Mlig455_055855 {REF} {Length: 2462} {TRANSSPLICED} {Pfam: Myotubularin-like phosphatase domain [PF06602.16, score=24.0]} {Human: ENSG00000163719, MTMR14, myotubularin related protein 14, [RH, Score=254, Expect=9e-78]} {Mouse: ENSMUSG00000030269, Mtmr14, myotubularin related protein 14, [RH, Score=251, Expect=6e-76]} {Dmel: FBgn0027506, EDTP, Egg-derived tyrosine phosphatase, [RH, Score=250, Expect=7e-75]} {Smed: dd_Smed_v6_6564_0_4, dd_Smed_v6_6564_0_4, [RH, Score=278, Expect=4e-88]} {RNA1509_26288, RNA1509_55802} {RNA1310_17788, RNA1509_26288, RNA1509_55802} {RNA1509_26288, RNA1509_55802, RNA815_7483.1}
11. MligTC455_28889 148 3.07 Mlig455_007222

Neo: -

Age: Down-Down-Up

 CNFN 0.974 - - - - 0.974 - Mlig455_007222 {REF} {Length: 9971} {TRANSSPLICED} {Pfam: PLAC8 family [PF04749.19, score=49.2]} {Human: ENSG00000105427, CNFN, cornifelin, [Score=45.1, Expect=4e-06]} {Mouse: ENSMUSG00000063651, Cnfn, cornifelin, [Score=46.6, Expect=9e-07]} {Smed: dd_Smed_v6_865_0_1, dd_Smed_v6_865_0_1, [Score=94.4, Expect=4e-25]} {RNA1509_12352, RNA1509_36973} {RNA1310_2280.1, RNA1509_36973} {RNA1509_36973, RNA815_459.1}
12. MligTC455_22477 33 0.68 Mlig455_001151

Neo: -

Age: -

 0.972 - - - - 0.972 - Mlig455_001151 {REF} {Length: 2314} {NoTransDecoderORF} {RNA1509_20868} {RNA1310_38923} {RNA815_3666.1}
13. MligTC455_47997 36 0.75 Mlig455_053262, Mlig455_065031

Neo: -

Age: -

 0.97 - - - - 0.970 -

Mlig455_053262 {REF} {Length: 927} {RNA1310_55950} {RNA815_42062.2}

Mlig455_065031 {REF} {Length: 926} {RNA1310_55950} {RNA815_42062.2}
14. MligTC455_18133 317 6.61 Mlig455_000484

Neo: -

Age: -

 CRAMP1 0.969 - - 0.969 - - - Mlig455_000484 {REF} {Length: 3860} {TRANSSPLICED} {Pfam: Myb-like DNA-binding domain [PF00249.33, score=20.8]} {Human: ENSG00000007545, CRAMP1, cramped chromatin regulator homolog 1, [RH, Score=134, Expect=1e-31]} {Mouse: ENSMUSG00000038002, Cramp1l, cramped chromatin regulator homolog 1, [RH, Score=134, Expect=7e-32]} {Dmel: FBgn0000376, crm, cramped, [RH, Score=144, Expect=4e-35]} {Smed: dd_Smed_v6_6124_0_1, dd_Smed_v6_6124_0_1, [RH, Score=270, Expect=4e-79]} {RNA1509_20088} {RNA1310_14330} {RNA815_29842}
15. MligTC455_11307 18 0.38 Mlig455_008154

Neo: -

Age: -

 ASIC5 0.968 - - - - 0.968 - Mlig455_008154 {REF} {Length: 3131} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=200.0]} {Human: ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=68.2, Expect=2e-11]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=72.0, Expect=1e-12]} {Celegans: WBGene00001465, flr-1, FLR-1, [RH, Score=59.7, Expect=5e-09]} {Smed: dd_Smed_v6_12037_0_1, dd_Smed_v6_12037_0_1, [RH, Score=449, Expect=2e-149]} {RNA1509_30695} {RNA1310_81096} {RNA815_21455}
16. MligTC455_52861 31 0.64 Mlig455_049513

Neo: -

Age: -

 GNAO1 0.964 - - - - 0.964 - Mlig455_049513 {REF} {Length: 3228} {Pfam: G-protein alpha subunit [PF00503.22, score=252.5]; ADP-ribosylation factor family [PF00025.23, score=43.6]; Rad17 P-loop domain [PF03215.17, score=22.1]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000087258, GNAO1, G protein subunit alpha o1, [Score=152, Expect=4e-40]; ENSG00000114353, GNAI2, G protein subunit alpha i2, [Score=147, Expect=2e-38]} {Mouse: ENSMUSG00000032562, Gnai2, guanine nucleotide binding protein (G protein), alpha inhibiting 2, [Score=149, Expect=2e-39]; ENSMUSG00000031748, Gnao1, guanine nucleotide binding protein, alpha O, [Score=149, Expect=2e-39]; ENSMUSG00000057614, Gnai1, guanine nucleotide binding protein (G protein), alpha inhibiting 1, [Score=143, Expect=4e-37]; ENSMUSG00000000001, Gnai3, guanine nucleotide binding protein (G protein), alpha inhibiting 3, [Score=142, Expect=1e-36]} {Dmel: FBgn0001104, Galphai, G protein alpha i subunit, [Score=150, Expect=1e-39]} {Celegans: WBGene00001677, gpa-15, Guanine nucleotide-binding protein alpha-15 subunit, [Score=156, Expect=4e-42]} {Smed: dd_Smed_v6_22522_0_2, dd_Smed_v6_22522_0_2, [RH, Score=231, Expect=9e-69]} {RNA1509_23459} {RNA1310_51930} {RNA815_22610}
17. MligTC455_19554 56 1.16 Mlig455_060596

Neo: -

Age: -

 0.963 - - - - 0.963 - Mlig455_060596 {REF} {Length: 2387} {NoTransDecoderORF} {RNA1509_45664} {RNA1310_50767}
18. MligTC455_23047 66 1.36 Mlig455_057970

Neo: -

Age: Up-Down-Down

 SGSM1 0.963 - - 0.963 - - - Mlig455_057970 {REF} {Length: 4688} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=83.8]; RUN domain [PF02759.21, score=76.3]; Rab-binding domain (RBD) [PF12068.10, score=74.4]} {Human: ENSG00000167037, SGSM1, small G protein signaling modulator 1, [RH, Score=370, Expect=4e-109]} {Mouse: ENSMUSG00000042216, Sgsm1, small G protein signaling modulator 1, [RH, Score=367, Expect=4e-112]} {Dmel: FBgn0031116, CG1695, [Score=381, Expect=6e-113]} {Celegans: WBGene00008018, tbc-8, TBC (Tre-2/Bub2/Cdc16) domain family, [Score=219, Expect=1e-58]} {Smed: dd_Smed_v6_12130_0_1, dd_Smed_v6_12130_0_1, [Score=474, Expect=2e-148]} {RNA1310_35495.2} {RNA815_26008}
19. MligTC455_29343 88 1.83 Mlig455_063181

Neo: -

Age: Down-Up-Up

 SIDT1 0.963 - - 0.963 - - - Mlig455_063181 {REF} {Length: 3188} {Pfam: dsRNA-gated channel SID-1 [PF13965.8, score=382.4]} {Human: ENSG00000072858, SIDT1, SID1 transmembrane family member 1, [Score=247, Expect=9e-70]} {Mouse: ENSMUSG00000022696, Sidt1, SID1 transmembrane family, member 1, [Score=232, Expect=1e-64]; ENSMUSG00000034908, Sidt2, SID1 transmembrane family, member 2, [Score=228, Expect=8e-63]} {Celegans: WBGene00006477, chup-1, CHolesterol UPtake associated, [Score=209, Expect=5e-57]} {Smed: dd_Smed_v6_6063_0_1, dd_Smed_v6_6063_0_1, [Score=242, Expect=8e-69]} {RNA1509_22787} {RNA1310_4984} {RNA815_5225}
20. MligTC455_45389 18 0.37 Mlig455_040503, Mlig455_057939

Neo: -

Age: -

 0.961 - - - - - 0.961

Mlig455_040503 {REF} {Length: 804} {RNA1509_26883} {RNA1310_27896} {RNA815_42909}

Mlig455_057939 {REF} {Length: 1147} {RNA1509_26883} {RNA1310_27896} {RNA815_42909}
21. MligTC455_21210 58 1.21 Mlig455_054815, Mlig455_054824

Neo: -

Age: -

 0.96 - 0.960 - - - -

Mlig455_054815 {REF} {Length: 1627} {Celegans: WBGene00044176, C30G7.2, [Score=80.9, Expect=2e-19]} {Smed: dd_Smed_v6_8948_0_1, dd_Smed_v6_8948_0_1, [RH, Score=90.9, Expect=9e-24]} {RNA1509_36146} {RNA1310_58910} {RNA815_43112}

Mlig455_054824 {REF} {Length: 2264} {Celegans: WBGene00044176, C30G7.2, [Score=80.9, Expect=2e-19]} {Smed: dd_Smed_v6_8948_0_1, dd_Smed_v6_8948_0_1, [RH, Score=90.9, Expect=9e-24]} {RNA1509_36146} {RNA1310_58910} {RNA815_43112}
22. MligTC455_04625 54 1.12 Mlig455_031551, Mlig455_031554

Neo: -

Age: -

 FHAD1 0.959 - 0.959 - - - -

Mlig455_031551 {REF} {Length: 1252} {Pfam: FHA domain [PF00498.28, score=38.1]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.3]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=66.2, Expect=1e-11]} {RNA1509_11172} {RNA1310_2117.1} {RNA815_31030}

Mlig455_031554 {REF} {Length: 5287} {Pfam: FHA domain [PF00498.28, score=36.7]; Inner membrane component of T3SS, cytoplasmic domain [PF16697.7, score=33.0]} {Human: ENSG00000142621, FHAD1, forkhead associated phosphopeptide binding domain 1, [Score=130, Expect=4e-31]} {Mouse: ENSMUSG00000051435, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=129, Expect=1e-29]; ENSMUSG00000116181, Fhad1, forkhead-associated (FHA) phosphopeptide binding domain 1, [Score=129, Expect=1e-29]} {Smed: dd_Smed_v6_14350_0_1, dd_Smed_v6_14350_0_1, [Score=252, Expect=3e-68]} {RNA1509_11172} {RNA1310_2117.1} {RNA815_6949}
23. MligTC455_05445 216 4.5 Mlig455_057834, Mlig455_057845

Neo: Irradiation

Age: -

Region-enriched R5: 4.010/0.00000

 0.959 - - - 0.959 - -

Mlig455_057834 {REF} {Length: 2777} {Pfam: Mab-21 protein [PF03281.16, score=28.6]} {RNA1509_21275} {RNA1310_27488} {RNA815_25797}

Mlig455_057845 {REF} {Length: 2779} {Pfam: Mab-21 protein [PF03281.16, score=28.7]} {RNA1509_21275} {RNA1310_27488} {RNA815_25797}
24. MligTC455_16375 99 2.05 Mlig455_030691

Neo: -

Age: -

Region-enriched R8: 3.721/0.03273

 RAPGEF2 0.958 - - - - 0.958 - Mlig455_030691 {REF} {Length: 1157} {Pfam: RasGEF domain [PF00617.21, score=62.0]} {Human: ENSG00000109756, RAPGEF2, Rap guanine nucleotide exchange factor 2, [Score=78.2, Expect=2e-15]} {Mouse: ENSMUSG00000062232, Rapgef2, Rap guanine nucleotide exchange factor (GEF) 2, [Score=77.4, Expect=2e-15]} {Dmel: FBgn0085421, Epac, Exchange protein directly activated by cAMP, [Score=66.6, Expect=7e-12]} {Celegans: WBGene00004254, pxf-1, Rap guanine nucleotide exchange factor, [Score=69.3, Expect=8e-13]} {Smed: dd_Smed_v6_4950_0_2, dd_Smed_v6_4950_0_2, [Score=61.2, Expect=3e-10]} {RNA1310_33127.1} {RNA815_48107}
25. MligTC455_33264 88 1.84 Mlig455_055165

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-1.707

 SLC17A8 0.958 - 0.958 - - - - Mlig455_055165 {REF} {Length: 2530} {Pfam: Major Facilitator Superfamily [PF07690.18, score=65.4]} {Human: ENSG00000179520, SLC17A8, solute carrier family 17 member 8, [Score=129, Expect=5e-31]; ENSG00000091664, SLC17A6, solute carrier family 17 member 6, [Score=128, Expect=6e-31]; ENSG00000104888, SLC17A7, solute carrier family 17 member 7, [Score=124, Expect=1e-29]} {Mouse: ENSMUSG00000070570, Slc17a7, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7, [Score=130, Expect=1e-31]; ENSMUSG00000019935, Slc17a8, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8, [Score=130, Expect=2e-31]; ENSMUSG00000030500, Slc17a6, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6, [Score=130, Expect=1e-31]} {Dmel: FBgn0031424, VGlut, Vesicular glutamate transporter, [Score=112, Expect=6e-26]} {Celegans: WBGene00017681, slc-17.5, SLC (SoLute Carrier) homolog, [Score=66.6, Expect=2e-11]} {Smed: dd_Smed_v6_10192_0_1, dd_Smed_v6_10192_0_1, [Score=125, Expect=3e-30]} {RNA1509_54006} {RNA1310_10685, RNA1509_54006} {RNA1509_54006, RNA815_25744}
26. MligTC455_08134 23 0.47 Mlig455_027743

Neo: -

Age: -

 0.957 - - - - 0.957 - Mlig455_027743 {REF} {Length: 813} {NoTransDecoderORF} {RNA1310_53853} {RNA815_56009}
27. MligTC455_32589 28 0.59 Mlig455_002986

Neo: -

Age: -

 0.957 - - - - 0.957 - Mlig455_002986 {REF} {Length: 2772} {NoTransDecoderORF} {RNA1509_48406} {RNA1310_45362.1} {RNA815_49063.1}
28. MligTC455_11326 37 0.78 Mlig455_052259

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_052259 {REF} {Length: 631} {NoTransDecoderORF} {RNA1509_23259} {RNA1310_20623} {RNA815_40388}
29. MligTC455_14329 326 6.78 Mlig455_038755

Neo: -

Age: logFC(26M/2M)=2.873

 CYP2U1 0.956 - - - - 0.956 - Mlig455_038755 {REF} {Length: 2107} {Pfam: Cytochrome P450 [PF00067.24, score=302.2]} {Human: ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=211, Expect=2e-61]; ENSG00000108242, CYP2C18, cytochrome P450 family 2 subfamily C member 18, [Score=204, Expect=2e-59]; ENSG00000138115, CYP2C8, cytochrome P450 family 2 subfamily C member 8, [Score=202, Expect=1e-58]} {Mouse: ENSMUSG00000032808, Cyp2c38, cytochrome P450, family 2, subfamily c, polypeptide 38, [Score=213, Expect=1e-62]; ENSMUSG00000025003, Cyp2c39, cytochrome P450, family 2, subfamily c, polypeptide 39, [Score=213, Expect=9e-63]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=209, Expect=7e-61]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=209, Expect=7e-61]; ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=208, Expect=8e-61]; ENSMUSG00000052974, Cyp2f2, cytochrome P450, family 2, subfamily f, polypeptide 2, [Score=204, Expect=1e-59]; ENSMUSG00000025002, Cyp2c55, cytochrome P450, family 2, subfamily c, polypeptide 55, [Score=204, Expect=1e-59]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=176, Expect=9e-49]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=206, Expect=1e-60]} {Smed: dd_Smed_v6_2083_0_1, dd_Smed_v6_2083_0_1, [Score=230, Expect=2e-69]} {RNA1509_33783} {RNA1310_2911.1, RNA1509_33783} {RNA1509_33783, RNA815_12179}
30. MligTC455_09558 10 0.21 Mlig455_038685

Neo: -

Age: -

 0.955 - - - - 0.955 - Mlig455_038685 {REF} {Length: 1419} {NoTransDecoderORF} {RNA1509_47234} {RNA1310_13305.1} {RNA815_19184}
31. MligTC455_14426 7 0.14 Mlig455_004014

Neo: -

Age: -

 0.955 - - - - 0.955 - Mlig455_004014 {REF} {Length: 1248} {NoTransDecoderORF} {RNA1509_28689} {RNA1310_45336} {RNA815_53932}
32. MligTC455_22290 183 3.81 Mlig455_040348, Mlig455_052968

Neo: -

Age: -

 0.955 - - - - 0.955 -

Mlig455_040348 {REF} {Length: 4187} {NoTransDecoderORF} {RNA1509_42337} {RNA1310_42816} {RNA815_26632}

Mlig455_052968 {REF} {Length: 105} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_42337} {RNA1310_27723} {RNA815_11170.1}
33. MligTC455_19938 250 5.2 Mlig455_063706

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.458

Region-enriched R3: 3.513/0.03723

 NKX2-2 0.954 - 0.954 - - - - Mlig455_063706 {REF} {Length: 2739} {Pfam: Homeodomain [PF00046.31, score=72.6]} {Human: ENSG00000125820, NKX2-2, NK2 homeobox 2, [Score=119, Expect=3e-31]} {Mouse: ENSMUSG00000027434, Nkx2-2, NK2 homeobox 2, [Score=119, Expect=1e-31]} {Dmel: FBgn0261930, vnd, ventral nervous system defective, [Score=112, Expect=2e-27]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [Score=95.9, Expect=8e-23]} {Smed: dd_Smed_v6_2716_0_4, dd_Smed_v6_2716_0_4, [Score=118, Expect=4e-30]} {RNA1509_27298} {RNA1310_16689.1, RNA1509_27298} {RNA1509_27298, RNA815_30453}
34. MligTC455_29181 37 0.78 Mlig455_067970

Neo: -

Age: Up-Down-Down

 DNAH5 0.952 - - - - 0.952 - Mlig455_067970 {REF} {Length: 9766} {Pfam: Dynein heavy chain, N-terminal region 1 [PF08385.14, score=581.8]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=435.1]; Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=417.2]; P-loop containing dynein motor region [PF12775.9, score=231.5]; P-loop containing dynein motor region D4 [PF12780.9, score=129.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=79.8]; Dynein heavy chain AAA lid domain [PF17852.3, score=64.9]; AAA+ lid domain [PF17857.3, score=63.0]; AAA ATPase domain [PF13191.8, score=28.7]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=24.6]; AAA domain [PF13401.8, score=21.4]; P-loop containing region of AAA domain [PF13555.8, score=20.8]} {Human: ENSG00000039139, DNAH5, dynein axonemal heavy chain 5, [Score=3811, Expect=0.0]} {Mouse: ENSMUSG00000022262, Dnah5, dynein, axonemal, heavy chain 5, [Score=3798, Expect=0.0]} {Dmel: FBgn0037726, CG9492, [Score=2985, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=721, Expect=0.0]} {Smed: dd_Smed_v6_4569_0_1, dd_Smed_v6_4569_0_1, [Score=4310, Expect=0.0]} {RNA1509_653} {RNA1310_37.1} {RNA815_534.1}
35. MligTC455_38854 30 0.62 Mlig455_014674

Neo: -

Age: -

 0.952 - - - 0.952 - - Mlig455_014674 {REF} {Length: 1824} {RNA1509_39463} {RNA1310_39338} {RNA815_20734.1}
36. MligTC455_49447 105 2.2 Mlig455_027882

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.491

 PRKCZ 0.95 - 0.950 - - - - Mlig455_027882 {REF} {Length: 2617} {Pfam: Protein kinase domain [PF00069.27, score=120.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=83.0]; Kinase-like [PF14531.8, score=25.0]} {Human: ENSG00000067606, PRKCZ, protein kinase C zeta, [Score=89.0, Expect=3e-18]; ENSG00000065675, PRKCQ, protein kinase C theta, [Score=88.2, Expect=5e-18]; ENSG00000163558, PRKCI, protein kinase C iota, [Score=88.2, Expect=4e-18]; ENSG00000027075, PRKCH, protein kinase C eta, [Score=87.8, Expect=6e-18]; ENSG00000108443, RPS6KB1, ribosomal protein S6 kinase B1, [Score=87.8, Expect=5e-18]; ENSG00000117676, RPS6KA1, ribosomal protein S6 kinase A1, [Score=86.3, Expect=2e-17]; ENSG00000281877, RPS6KA1, ribosomal protein S6 kinase A1, [Score=86.3, Expect=2e-17]; ENSG00000171132, PRKCE, protein kinase C epsilon, [Score=85.9, Expect=4e-17]} {Mouse: ENSMUSG00000021108, Prkch, protein kinase C, eta, [Score=88.6, Expect=3e-18]; ENSMUSG00000029053, Prkcz, protein kinase C, zeta, [Score=88.2, Expect=3e-18]; ENSMUSG00000037643, Prkci, protein kinase C, iota, [Score=87.8, Expect=4e-18]; ENSMUSG00000020516, Rps6kb1, ribosomal protein S6 kinase, polypeptide 1, [Score=87.4, Expect=5e-18]; ENSMUSG00000025665, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=85.9, Expect=3e-17]; ENSMUSG00000116203, Rps6ka6, ribosomal protein S6 kinase polypeptide 6, [Score=85.9, Expect=3e-17]; ENSMUSG00000003644, Rps6ka1, ribosomal protein S6 kinase polypeptide 1, [Score=85.5, Expect=3e-17]; ENSMUSG00000045038, Prkce, protein kinase C, epsilon, [Score=85.1, Expect=5e-17]; ENSMUSG00000026778, Prkcq, protein kinase C, theta, [Score=84.3, Expect=7e-17]; ENSMUSG00000019699, Akt3, thymoma viral proto-oncogene 3, [Score=84.3, Expect=5e-17]} {Dmel: FBgn0003093, Pkc98E, Protein C kinase 98E, [Score=87.0, Expect=6e-18]} {Celegans: WBGene00004032, pkc-1, Protein kinase C-like 1B, [Score=85.1, Expect=2e-17]} {Smed: dd_Smed_v6_8010_0_1, dd_Smed_v6_8010_0_1, [Score=88.6, Expect=1e-18]} {RNA1509_20079, RNA1509_52166} {RNA1310_18713, RNA1509_20079, RNA1509_52166} {RNA1509_20079, RNA1509_52166, RNA815_7871}

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