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Results for MligTC455_27784

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_27784 357 7.44 Mlig455_058367

Neo: -

Age: Down-Up-Down

PAK3 Mlig455_058367 {REF} {Length: 3790} {Pfam: Protein kinase domain [PF00069.27, score=237.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.0]; P21-Rho-binding domain [PF00786.30, score=34.0]; ABC1 atypical kinase-like domain [PF03109.18, score=25.7]; Kinase-like [PF14531.8, score=23.8]; Fungal protein kinase [PF17667.3, score=22.8]; Phosphotransferase enzyme family [PF01636.25, score=20.3]} {Human: ENSG00000077264, PAK3, p21 (RAC1) activated kinase 3, [Score=349, Expect=9e-113]; ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=334, Expect=3e-107]; ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=332, Expect=3e-106]} {Mouse: ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=333, Expect=3e-107]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [Score=332, Expect=2e-106]; ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=332, Expect=2e-106]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=331, Expect=8e-103]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=321, Expect=9e-104]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [RH, Score=368, Expect=8e-122]} {RNA1509_4715} {RNA1310_5360.1} {RNA815_4593}

Cumulative graph for MligTC455_27784

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -5.735 3.255 0.16638 0.79050
RegionR2 0.566 3.255 0.56078 0.92317
RegionR3 0.106 3.255 0.81041 1.00000
RegionR4 0.751 3.255 0.43854 0.76727
RegionR5 0.991 3.255 0.20879 0.50395
RegionR6 0.651 3.255 0.47540 1.00000
RegionR7 0.94 3.255 0.35000 0.98654
RegionR8 1.729 3.255 0.09442 0.58013

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 5.315 3.255 0.28947 0.98735
RegenerationR2 0.425 3.255 0.36220 0.79019
RegenerationR3 0.82 3.255 0.15308 0.58283
RegenerationR4 0.349 3.255 0.54493 0.89050
RegenerationR5 0.142 3.255 0.77369 0.98015
RegenerationR6 0.727 3.255 0.19121 0.52944
RegenerationBL 0.629 3.255 0.28685 0.64852
RegenerationTP -1.015 3.255 0.18176 0.61735


Genes with expression patterns similar to MligTC455_27784

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_27784 357 7.44 Mlig455_058367

Neo: -

Age: Down-Up-Down

PAK3 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_058367 {REF} {Length: 3790} {Pfam: Protein kinase domain [PF00069.27, score=237.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=162.0]; P21-Rho-binding domain [PF00786.30, score=34.0]; ABC1 atypical kinase-like domain [PF03109.18, score=25.7]; Kinase-like [PF14531.8, score=23.8]; Fungal protein kinase [PF17667.3, score=22.8]; Phosphotransferase enzyme family [PF01636.25, score=20.3]} {Human: ENSG00000077264, PAK3, p21 (RAC1) activated kinase 3, [Score=349, Expect=9e-113]; ENSG00000180370, PAK2, p21 (RAC1) activated kinase 2, [Score=334, Expect=3e-107]; ENSG00000149269, PAK1, p21 (RAC1) activated kinase 1, [Score=332, Expect=3e-106]} {Mouse: ENSMUSG00000022781, Pak2, p21 (RAC1) activated kinase 2, [Score=333, Expect=3e-107]; ENSMUSG00000031284, Pak3, p21 (RAC1) activated kinase 3, [Score=332, Expect=2e-106]; ENSMUSG00000030774, Pak1, p21 (RAC1) activated kinase 1, [Score=332, Expect=2e-106]} {Dmel: FBgn0267698, Pak, p21-activated kinase, [Score=331, Expect=8e-103]} {Celegans: WBGene00003144, max-2, Serine/threonine-protein kinase max-2, [Score=321, Expect=9e-104]} {Smed: dd_Smed_v6_1765_0_1, dd_Smed_v6_1765_0_1, [RH, Score=368, Expect=8e-122]} {RNA1509_4715} {RNA1310_5360.1} {RNA815_4593}
2. MligTC455_17952 858 17.88 Mlig455_019484, Mlig455_060545

Neo: -

Age: -

1.775 - - - 0.973 0.802 -

Mlig455_019484 {REF} {Length: 4698} {TRANSSPLICED} {Smed: dd_Smed_v6_9197_0_1, dd_Smed_v6_9197_0_1, [Score=49.3, Expect=1e-05]} {RNA1509_4363, RNA1509_50959} {RNA1310_1338, RNA1509_50959} {RNA1509_50959, RNA815_4509}

Mlig455_060545 {REF} {Length: 4765} {Dmel: FBgn0261934, dikar, [Score=51.2, Expect=8e-06]} {Smed: dd_Smed_v6_9197_0_1, dd_Smed_v6_9197_0_1, [RH, Score=100, Expect=2e-21]} {RNA1509_4363} {RNA1310_1338} {RNA815_4509}
3. MligTC455_17953 432 9 Mlig455_066894

Neo: -

Age: -

1.774 - - - 0.971 0.803 - Mlig455_066894 {REF} {Length: 4710} {TRANSSPLICED} {Smed: dd_Smed_v6_9197_0_1, dd_Smed_v6_9197_0_1, [Score=49.3, Expect=1e-05]} {RNA1509_4363} {RNA1310_1338} {RNA815_4509}
4. MligTC455_33686 84 1.75 Mlig455_006610, Mlig455_022375

Neo: -

Age: -

1.773 - - - 0.950 0.823 -

Mlig455_006610 {REF} {Length: 515} {NoTransDecoderORF} {RNA1509_32404} {RNA1310_54013.1} {RNA815_47584}

Mlig455_022375 {REF} {Length: 2487} {NoTransDecoderORF} {RNA1509_32404} {RNA1310_108649} {RNA815_38663}
5. MligTC455_17188 620 12.91 Mlig455_001427

Neo: -

Age: Up-Down-Down

OTOP2 1.717 - - 0.745 0.972 - - Mlig455_001427 {REF} {Length: 4075} {TRANSSPLICED} {Pfam: Otopetrin [PF03189.15, score=232.0]} {Human: ENSG00000183034, OTOP2, otopetrin 2, [Score=55.5, Expect=4e-07]} {Mouse: ENSMUSG00000050201, Otop2, otopetrin 2, [Score=69.3, Expect=1e-11]} {Dmel: FBgn0259150, CG42265, [Score=158, Expect=3e-39]} {Celegans: WBGene00010403, otpl-8, OToPetrin-Like, [Score=115, Expect=2e-26]} {Smed: dd_Smed_v6_13612_0_2, dd_Smed_v6_13612_0_2, [Score=162, Expect=8e-42]} {RNA1509_11389, RNA1509_24948} {RNA1310_7296.2, RNA1509_11389, RNA1509_24948} {RNA1509_11389, RNA1509_24948, RNA815_3560.1}
6. MligTC455_17889 170 3.54 Mlig455_046543

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-0.539

ELF2 1.706 - - 0.956 0.750 - - Mlig455_046543 {REF} {Length: 3197} {Pfam: Ets-domain [PF00178.24, score=109.4]} {Human: ENSG00000109381, ELF2, E74 like ETS transcription factor 2, [RH, Score=160, Expect=1e-42]} {Mouse: ENSMUSG00000037174, Elf2, E74-like factor 2, [RH, Score=158, Expect=9e-43]} {Dmel: FBgn0000567, Eip74EF, Ecdysone-induced protein 74EF, [RH, Score=160, Expect=2e-42]} {Celegans: WBGene00016029, elf-1, See eff, [RH, Score=153, Expect=7e-42]} {Smed: dd_Smed_v6_6626_0_1, dd_Smed_v6_6626_0_1, [RH, Score=119, Expect=5e-31]} {RNA1509_8339} {RNA1310_13082} {RNA815_2627}
7. MligTC455_43550 1501 31.28 Mlig455_065262

Neo: -

Age: -

SSBP3 1.696 - - - 0.967 0.729 - Mlig455_065262 {REF} {Length: 4032} {Human: ENSG00000157216, SSBP3, single stranded DNA binding protein 3, [RH, Score=186, Expect=1e-54]; ENSG00000145687, SSBP2, single stranded DNA binding protein 2, [RH, Score=185, Expect=1e-54]} {Mouse: ENSMUSG00000061887, Ssbp3, single-stranded DNA binding protein 3, [RH, Score=186, Expect=1e-54]; ENSMUSG00000003992, Ssbp2, single-stranded DNA binding protein 2, [RH, Score=185, Expect=8e-55]} {Dmel: FBgn0011481, Ssdp, Sequence-specific single-stranded DNA-binding protein, [RH, Score=192, Expect=2e-56]} {Celegans: WBGene00012990, sam-10, Single-stranded DNA-binding protein homolog sam-10, [RH, Score=91.3, Expect=6e-20]} {Smed: dd_Smed_v6_3876_0_1, dd_Smed_v6_3876_0_1, [RH, Score=178, Expect=2e-51]} {RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152} {RNA1310_27347, RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152} {RNA1509_12630, RNA1509_17189, RNA1509_19453, RNA1509_29837, RNA1509_36215, RNA1509_39481, RNA1509_51894, RNA1509_55152, RNA815_18789}
8. MligTC455_19743 540 11.25 Mlig455_048824

Neo: -

Age: Up-Down-Down

FMNL3 0.979 - - - 0.979 - - Mlig455_048824 {REF} {Length: 4388} {TRANSSPLICED} {Pfam: Formin Homology 2 Domain [PF02181.25, score=255.2]; Diaphanous GTPase-binding Domain [PF06371.15, score=78.4]; Diaphanous FH3 Domain [PF06367.18, score=47.5]} {Human: ENSG00000161791, FMNL3, formin like 3, [Score=274, Expect=5e-77]; ENSG00000184922, FMNL1, formin like 1, [Score=269, Expect=6e-78]} {Mouse: ENSMUSG00000036053, Fmnl2, formin-like 2, [RH, Score=386, Expect=3e-117]} {Dmel: FBgn0267795, Frl, Formin-like, [RH, Score=307, Expect=7e-88]} {Celegans: WBGene00021698, frl-1, FRL (Formin Related gene in Leukocytes) homolog, [Score=173, Expect=8e-44]} {Smed: dd_Smed_v6_3928_0_2, dd_Smed_v6_3928_0_2, [RH, Score=456, Expect=6e-144]} {RNA1509_13312, RNA1509_23073, RNA1509_50834, RNA1509_55866} {RNA1310_6955.1, RNA1509_13312, RNA1509_23073, RNA1509_50834, RNA1509_55866} {RNA1509_13312, RNA1509_23073, RNA1509_50834, RNA1509_55866, RNA815_1314}
9. MligTC455_30068 481 10.03 Mlig455_008201

Neo: -

Age: Up-Down-Down

0.971 - - - 0.971 - - Mlig455_008201 {REF} {Length: 5834} {TRANSSPLICED} {RNA1509_32679} {RNA1310_14141.1} {RNA815_19001}
10. MligTC455_52795 674 14.04 Mlig455_058194

Neo: -

Age: -

TMEM117 0.956 - - - 0.956 - - Mlig455_058194 {REF} {Length: 4435} {TRANSSPLICED} {Pfam: TMEM117 protein family [PF15113.8, score=543.0]} {Human: ENSG00000139173, TMEM117, transmembrane protein 117, [RH, Score=419, Expect=3e-137]} {Mouse: ENSMUSG00000063296, Tmem117, transmembrane protein 117, [RH, Score=422, Expect=5e-139]} {RNA1509_36999, RNA1509_4844} {RNA1310_1174, RNA1509_36999, RNA1509_4844} {RNA1509_36999, RNA1509_4844, RNA815_2317.1}
11. MligTC455_23405 1199 24.97 Mlig455_019205

Neo: -

Age: -

ADAMTSL1 0.953 - - - 0.953 - - Mlig455_019205 {REF} {Length: 3744} {TRANSSPLICED} {Pfam: Thrombospondin type 1 domain [PF19030.2, score=110.2]; Thrombospondin type 1 domain [PF00090.21, score=28.8]; Immunoglobulin domain [PF13927.8, score=24.4]; PLAC (protease and lacunin) domain [PF08686.13, score=21.3]} {Human: ENSG00000178031, ADAMTSL1, ADAMTS like 1, [RH, Score=114, Expect=3e-25]} {Mouse: ENSMUSG00000066113, Adamtsl1, ADAMTS-like 1, [RH, Score=113, Expect=4e-25]} {Dmel: FBgn0051619, nolo, no long nerve cord, [RH, Score=100, Expect=3e-21]} {Celegans: WBGene00009958, madd-4, [RH, Score=167, Expect=4e-43]} {Smed: dd_Smed_v6_6962_0_1, dd_Smed_v6_6962_0_1, [RH, Score=184, Expect=6e-50]} {RNA1509_4750} {RNA1310_2104.1, RNA1509_4750} {RNA1509_4750, RNA815_1856.1}
12. MligTC455_29820 851 17.74 Mlig455_044549

Neo: -

Age: -

0.953 - - - 0.953 - - Mlig455_044549 {REF} {Length: 4558} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4139) [PF13598.8, score=141.2]; N-terminal domain of unknown function (DUF4140) [PF13600.8, score=74.2]} {Celegans: WBGene00016877, C52D10.3, [RH, Score=256, Expect=3e-76]} {Smed: dd_Smed_v6_3629_0_3, dd_Smed_v6_3629_0_3, [RH, Score=422, Expect=4e-140]} {RNA1509_3204} {RNA1310_1539.2} {RNA815_467.1}
13. MligTC455_22201 892 18.59 Mlig455_045089

Neo: -

Age: -

Region-enriched R7: 1.426/0.02956

Regeneration-upregulated BL: 1.589

Regeneration-enriched BL: 1.589

TLL1 0.952 - - - 0.952 - - Mlig455_045089 {REF} {Length: 3960} {Pfam: CUB domain [PF00431.22, score=500.8]; Astacin (Peptidase family M12A) [PF01400.26, score=226.0]; Coagulation Factor Xa inhibitory site [PF14670.8, score=57.7]; Calcium-binding EGF domain [PF07645.17, score=41.2]; Complement Clr-like EGF-like [PF12662.9, score=32.2]; EGF domain [PF12947.9, score=24.5]; CUB-like domain [PF02408.22, score=24.0]; Human growth factor-like EGF [PF12661.9, score=21.4]; EGF-like domain [PF00008.29, score=20.3]} {Human: ENSG00000038295, TLL1, tolloid like 1, [RH, Score=877, Expect=0.0]; ENSG00000095587, TLL2, tolloid like 2, [RH, Score=876, Expect=0.0]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [RH, Score=865, Expect=0.0]} {Mouse: ENSMUSG00000025013, Tll2, tolloid-like 2, [RH, Score=881, Expect=0.0]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [RH, Score=867, Expect=0.0]; ENSMUSG00000053626, Tll1, tolloid-like, [RH, Score=863, Expect=0.0]} {Dmel: FBgn0004885, tok, tolkin, [RH, Score=864, Expect=0.0]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [RH, Score=716, Expect=0.0]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [RH, Score=888, Expect=0.0]} {RNA1509_7883} {RNA1310_2749, RNA1509_7883} {RNA1509_7883, RNA815_1455}
14. MligTC455_30067 152 3.17 Mlig455_008162

Neo: -

Age: -

0.952 - - - 0.952 - - Mlig455_008162 {REF} {Length: 4500} {TRANSSPLICED} {RNA1509_32679} {RNA1310_14141.1} {RNA815_4925.2}
15. MligTC455_30909 3582 74.63 Mlig455_043858

Neo: -

Age: -

RBMS2 0.95 - - - 0.950 - - Mlig455_043858 {REF} {Length: 4160} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=55.7]} {Human: ENSG00000076067, RBMS2, RNA binding motif single stranded interacting protein 2, [RH, Score=120, Expect=2e-28]; ENSG00000144642, RBMS3, RNA binding motif single stranded interacting protein 3, [RH, Score=114, Expect=2e-26]} {Mouse: ENSMUSG00000040043, Rbms2, RNA binding motif, single stranded interacting protein 2, [RH, Score=120, Expect=5e-29]; ENSMUSG00000026970, Rbms1, RNA binding motif, single stranded interacting protein 1, [RH, Score=114, Expect=1e-26]} {Dmel: FBgn0052423, shep, alan shepard, [RH, Score=105, Expect=2e-23]} {Celegans: WBGene00006331, sup-26, SUPpressor, [Score=111, Expect=8e-27]} {Smed: dd_Smed_v6_2612_0_2, dd_Smed_v6_2612_0_2, [RH, Score=111, Expect=4e-25]} {RNA1509_833} {RNA1310_2595.1} {RNA815_5711}

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