Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_27842 | 1017 | 21.19 | Mlig455_021051, Mlig455_052351 | Neo: - Age: Down-Down-Up Regeneration-enriched TP: 4.635 |
Mlig455_021051 {REF} {Length: 11271} {Pfam: Zinc knuckle [PF00098.25, score=18.6]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} Mlig455_052351 {REF} {Length: 9553} {TRANSSPLICED} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.3]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.6]; Integrase zinc binding domain [PF17921.3, score=71.0]; Integrase core domain [PF00665.28, score=47.5]; Aspartyl protease [PF13650.8, score=38.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=34.5]; Retroviral aspartyl protease [PF00077.22, score=26.8]; Aspartyl protease [PF09668.12, score=22.8]; Putative peptidase (DUF1758) [PF05585.14, score=21.8]; Retroviral aspartyl protease [PF08284.13, score=18.9]; DDE superfamily endonuclease [PF13358.8, score=18.6]} {Smed: dd_Smed_v6_1574_6_41, dd_Smed_v6_1574_6_41, [Score=335, Expect=6e-100]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.496 | 4.577 | 0.74936 | 1.00000 | |
RegionR2 | 1.557 | 4.577 | 0.06841 | 0.31790 | |
RegionR3 | 1.262 | 4.577 | 0.09197 | 0.53437 | |
RegionR4 | 1.545 | 4.577 | 0.06285 | 0.22518 | |
RegionR5 | 0.346 | 4.577 | 0.64560 | 0.99764 | |
RegionR6 | -0.538 | 4.577 | 0.60247 | 1.00000 | |
RegionR7 | -2.132 | 4.577 | 0.14425 | 0.70817 | |
RegionR8 | -2.536 | 4.577 | 0.21074 | 0.81407 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.176 | 4.577 | 0.93337 | 1.00000 | |
RegenerationR2 | 1.412 | 4.577 | 0.05254 | 0.37805 | |
RegenerationR3 | 1.358 | 4.577 | 0.07346 | 0.45316 | |
RegenerationR4 | 1.016 | 4.577 | 0.21512 | 0.66200 | |
RegenerationR5 | 1.76 | 4.577 | 0.02711 | 0.27973 | |
RegenerationR6 | 2.847 | 4.577 | 0.00254 | 0.05719 | |
RegenerationBL | 4.54 | 4.577 | 0.00000 | 0.00008 | |
RegenerationTP | 4.635 | 4.577 | 0.00006 | 0.00808 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_27842 | 1017 | 21.19 | Mlig455_021051, Mlig455_052351 | Neo: - Age: Down-Down-Up Regeneration-enriched TP: 4.635 |
6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_021051 {REF} {Length: 11271} {Pfam: Zinc knuckle [PF00098.25, score=18.6]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} Mlig455_052351 {REF} {Length: 9553} {TRANSSPLICED} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=128.3]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=113.8]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=76.6]; Integrase zinc binding domain [PF17921.3, score=71.0]; Integrase core domain [PF00665.28, score=47.5]; Aspartyl protease [PF13650.8, score=38.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=34.5]; Retroviral aspartyl protease [PF00077.22, score=26.8]; Aspartyl protease [PF09668.12, score=22.8]; Putative peptidase (DUF1758) [PF05585.14, score=21.8]; Retroviral aspartyl protease [PF08284.13, score=18.9]; DDE superfamily endonuclease [PF13358.8, score=18.6]} {Smed: dd_Smed_v6_1574_6_41, dd_Smed_v6_1574_6_41, [Score=335, Expect=6e-100]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} |
|
2. | MligTC455_27841 | 1118 | 23.3 | Mlig455_021442, Mlig455_037900 | Neo: - Age: - Regeneration-upregulated BL: 4.099 Regeneration-enriched BL: 4.099 |
5.488 | 0.991 | 0.798 | 0.952 | 0.971 | 0.987 | 0.789 | Mlig455_021442 {REF} {Length: 2929} {TRANSSPLICED} {Pfam: Zinc knuckle [PF00098.25, score=21.6]} {RNA1509_24163} {RNA1310_131.1} {RNA815_52.1} Mlig455_037900 {REF} {Length: 3423} {Pfam: Zinc knuckle [PF00098.25, score=20.8]} {RNA1509_24163} {RNA1310_131.1} {RNA815_52.1} |
|
3. | MligTC455_31934 | 382 | 7.96 | Mlig455_003763, Mlig455_043367 | Neo: - |
SETMAR | 4.453 | 0.820 | - | 0.838 | 0.955 | 0.984 | 0.856 | Mlig455_003763 {REF} {Length: 13315} {TRANSSPLICED} {Pfam: HTH domain in Mos1 transposase [PF17906.3, score=52.2]; Homeodomain-like domain [PF13565.8, score=29.6]; Transposase (partial DDE domain) [PF01359.20, score=29.0]; Helix-turn-helix domain (DUF4817) [PF16087.7, score=19.0]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=155, Expect=4e-42]} {Smed: dd_Smed_v6_52102_0_1, dd_Smed_v6_52102_0_1, [Score=56.2, Expect=4e-10]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} Mlig455_043367 {REF} {Length: 1188} {TRANSSPLICED} {Pfam: Homeodomain-like domain [PF13565.8, score=29.9]; Transposase (partial DDE domain) [PF01359.20, score=20.7]} {Human: ENSG00000170364, SETMAR, SET domain and mariner transposase fusion gene, [Score=136, Expect=2e-35]} {Smed: dd_Smed_v6_52102_0_1, dd_Smed_v6_52102_0_1, [Score=60.1, Expect=2e-11]} {RNA1509_27993} {RNA1310_29590.2} {RNA815_7268.1} |
4. | MligTC455_27839 | 307 | 6.4 | Mlig455_007792 | Neo: - Age: - |
2.539 | - | - | - | 0.846 | 0.968 | 0.725 | Mlig455_007792 {REF} {Length: 2271} {Pfam: Protein of unknown function (DUF1759) [PF03564.17, score=23.5]; Zinc knuckle [PF00098.25, score=22.0]} {RNA1509_24163} {RNA1310_131.1} {RNA815_52.1} | |
5. | MligTC455_29220 | 298 | 6.21 | Mlig455_053072 | Neo: - Age: Up-Up-Down, logFC(26M/2M)=0.724 Region-enriched R2: 2.616/0.03046 |
2.478 | 0.975 | - | 0.730 | 0.773 | - | - | Mlig455_053072 {REF} {Length: 8981} {Pfam: Helix-turn-helix [PF01381.24, score=36.9]; Kinetoplastid membrane protein 11 [PF03037.18, score=27.5]; Family of unknown function (DUF6374) [PF19901.1, score=26.8]; Domain of unknown function (DUF5053) [PF16476.7, score=26.7]; Maf N-terminal region [PF08383.13, score=19.4]} {RNA1509_50040} {RNA1310_688} {RNA815_433.1} | |
6. | MligTC455_27843 | 317 | 6.6 | Mlig455_054197 | Neo: - Age: - Regeneration-enriched R6: 4.237 |
1.874 | - | - | - | 0.953 | 0.921 | - | Mlig455_054197 {REF} {Length: 1106} {Pfam: Zinc knuckle [PF00098.25, score=22.3]} {RNA1509_40897} {RNA1310_131.1} {RNA815_52.1} | |
7. | MligTC455_23866 | 384 | 8.01 | Mlig455_002342 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.442 Region-enriched R5: 1.898/0.04942 |
MARS2 | 1.789 | - | - | - | 0.959 | 0.830 | - | Mlig455_002342 {REF} {Length: 2569} {TRANSSPLICED} {Pfam: tRNA synthetases class I (M) [PF09334.13, score=211.4]; tRNA synthetases class I (I, L, M and V) [PF00133.24, score=33.0]; Anticodon binding domain of methionyl tRNA ligase [PF19303.1, score=19.0]} {Human: ENSG00000247626, MARS2, methionyl-tRNA synthetase 2, mitochondrial, [Score=301, Expect=7e-95]} {Mouse: ENSMUSG00000046994, Mars2, methionine-tRNA synthetase 2 (mitochondrial), [Score=291, Expect=2e-91]} {Dmel: FBgn0027083, MetRS-m, Methionyl-tRNA synthetase, mitochondrial, [Score=310, Expect=6e-99]} {Celegans: WBGene00013678, Y105E8A.20, Methionyl-tRNA synthetase (Mitochondrial), [Score=291, Expect=3e-92]} {Smed: dd_Smed_v6_12525_0_2, dd_Smed_v6_12525_0_2, [Score=276, Expect=1e-86]} {RNA1509_34702} {RNA1310_17351} {RNA815_6878} |
8. | MligTC455_48454 | 602 | 12.54 | Mlig455_041932 | Neo: - Age: Down-Up-Down |
CCDC154 | 1.789 | 0.959 | - | - | - | 0.830 | - | Mlig455_041932 {REF} {Length: 4159} {Pfam: Coiled-coil domain-containing protein 154 [PF15450.8, score=111.7]} {Human: ENSG00000197599, CCDC154, coiled-coil domain containing 154, [Score=94.7, Expect=2e-19]} {Mouse: ENSMUSG00000059562, Ccdc154, coiled-coil domain containing 154, [Score=86.3, Expect=5e-17]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_10236_0_1, dd_Smed_v6_10236_0_1, [Score=407, Expect=1e-131]} {RNA1509_37351, RNA1509_5383} {RNA1310_2073.1, RNA1509_37351, RNA1509_5383} {RNA1509_37351, RNA1509_5383, RNA815_2050} |
9. | MligTC455_29628 | 238 | 4.96 | Mlig455_024037 | Neo: - Age: - |
1.697 | - | - | - | - | 0.959 | 0.738 | Mlig455_024037 {REF} {Length: 6871} {Celegans: WBGene00019192, H12I13.3, [Score=142, Expect=3e-39]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=115, Expect=2e-29]} {RNA1509_28643, RNA1509_8360} {RNA1310_576.1, RNA1509_28643, RNA1509_8360} {RNA1509_28643, RNA1509_8360, RNA815_1671.1} | |
10. | MligTC455_27834 | 437 | 9.11 | Mlig455_003625, Mlig455_044671 | Neo: - Age: logFC(26M/2M)=1.954 |
1.696 | - | - | - | 0.718 | 0.978 | - | Mlig455_003625 {REF} {Length: 8904} {TRANSSPLICED} {Pfam: Integrase zinc binding domain [PF17921.3, score=71.1]; Integrase core domain [PF00665.28, score=51.2]; DDE superfamily endonuclease [PF13358.8, score=21.8]} {Smed: dd_Smed_v6_1574_6_72, dd_Smed_v6_1574_6_72, [Score=205, Expect=2e-60]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} Mlig455_044671 {REF} {Length: 10362} {Pfam: Zinc knuckle [PF00098.25, score=20.8]} {RNA1509_6137} {RNA1310_131.1} {RNA815_52.1} |
|
11. | MligTC455_28321 | 81 | 1.69 | Mlig455_060693 | Neo: - Age: - |
1.662 | - | - | - | 0.703 | 0.959 | - | Mlig455_060693 {REF} {Length: 1631} {Pfam: DNA polymerase type B, organellar and viral [PF03175.15, score=46.4]; Recombination endonuclease VII [PF02945.17, score=22.6]} {Celegans: WBGene00022511, ZC53.4, [Score=177, Expect=4e-47]} {Smed: dd_Smed_v6_9974_1_5, dd_Smed_v6_9974_1_5, [Score=218, Expect=6e-63]} {RNA1509_8360} {RNA1310_576.1} {RNA815_1671.1} | |
12. | MligTC455_28928 | 58 | 1.21 | Mlig455_017643 | Neo: - Age: - |
0.956 | - | - | - | - | 0.956 | - | Mlig455_017643 {REF} {Length: 7040} {Pfam: Replication protein A OB domain [PF16900.7, score=65.3]; OB-fold nucleic acid binding domain [PF01336.27, score=33.0]} {RNA1509_57189} {RNA1310_50941.1} {RNA815_26807} | |
13. | MligTC455_21713 | 106 | 2.2 | Mlig455_003036, Mlig455_021077 | Neo: - Age: Up-Down-Down |
0.954 | - | - | - | - | 0.954 | - | Mlig455_003036 {REF} {Length: 6852} {NoTransDecoderORF} {RNA1509_9107} {RNA1310_45895} {RNA815_43984} Mlig455_021077 {REF} {Length: 378} {NoTransDecoderORF} {RNA1509_52677} {RNA1310_48522} |
|
14. | MligTC455_42881 | 3632 | 75.66 | Mlig455_008338 | Neo: - |
EEF2K | 0.954 | - | - | - | - | 0.954 | - | Mlig455_008338 {REF} {Length: 4193} {Pfam: Alpha-kinase family [PF02816.20, score=188.2]} {Human: ENSG00000103319, EEF2K, eukaryotic elongation factor 2 kinase, [RH, Score=338, Expect=6e-107]} {Mouse: ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=339, Expect=9e-104]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [RH, Score=320, Expect=2e-96]} {Smed: dd_Smed_v6_9576_0_1, dd_Smed_v6_9576_0_1, [Score=404, Expect=9e-131]} {RNA1509_1554} {RNA1310_5135.1} {RNA815_1164.1} |
15. | MligTC455_33622 | 44 | 0.92 | Mlig455_053946, Mlig455_060582 | Neo: - Age: Up-Down-Down |
MTNR1B | 0.953 | - | - | - | - | 0.953 | - | Mlig455_053946 {REF} {Length: 3240} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=33.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.1]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=136, Expect=4e-36]; ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=130, Expect=2e-32]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=126, Expect=1e-32]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=123, Expect=3e-30]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=122, Expect=5e-31]} {Dmel: FBgn0025631, moody, [Score=105, Expect=2e-24]} {Celegans: WBGene00001052, dop-1, DOPamine receptor, [Score=96.7, Expect=8e-22]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=203, Expect=2e-62]} {RNA1509_18800} {RNA1310_23658} {RNA815_33287} Mlig455_060582 {REF} {Length: 3239} {TRANSSPLICED} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=156.3]; Serpentine type 7TM GPCR chemoreceptor Srx [PF10328.11, score=33.1]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=25.1]} {Human: ENSG00000134640, MTNR1B, melatonin receptor 1B, [Score=136, Expect=4e-36]; ENSG00000102195, GPR50, G protein-coupled receptor 50, [Score=130, Expect=2e-32]} {Mouse: ENSMUSG00000050901, Mtnr1b, melatonin receptor 1B, [Score=126, Expect=1e-32]; ENSMUSG00000056380, Gpr50, G-protein-coupled receptor 50, [Score=123, Expect=3e-30]; ENSMUSG00000054764, Mtnr1a, melatonin receptor 1A, [Score=122, Expect=5e-31]} {Dmel: FBgn0025631, moody, [Score=105, Expect=2e-24]} {Celegans: WBGene00001052, dop-1, DOPamine receptor, [Score=96.7, Expect=8e-22]} {Smed: dd_Smed_v6_65999_0_1, dd_Smed_v6_65999_0_1, [Score=203, Expect=2e-62]} {RNA1509_18800} {RNA1310_23658} {RNA815_33287} |
16. | MligTC455_26615 | 572 | 11.92 | Mlig455_045072 | Neo: - Age: logFC(26M/2M)=-0.522 |
0.952 | 0.952 | - | - | - | - | - | Mlig455_045072 {REF} {Length: 1124} {RNA1509_43319} {RNA1310_55165, RNA1509_43319} {RNA1509_43319, RNA815_27927} | |
17. | MligTC455_31257 | 229 | 4.78 | Mlig455_070423 | Neo: - Age: - |
STK3 | 0.952 | - | - | - | 0.952 | - | - | Mlig455_070423 {REF} {Length: 3240} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=230.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=175.9]; C terminal SARAH domain of Mst1 [PF11629.10, score=69.2]; ABC1 atypical kinase-like domain [PF03109.18, score=37.8]; Fungal protein kinase [PF17667.3, score=36.0]} {Human: ENSG00000104375, STK3, serine/threonine kinase 3, [RH, Score=553, Expect=0.0]} {Mouse: ENSMUSG00000022329, Stk3, serine/threonine kinase 3, [RH, Score=548, Expect=0.0]; ENSMUSG00000018209, Stk4, serine/threonine kinase 4, [RH, Score=530, Expect=0.0]} {Dmel: FBgn0261456, hpo, hippo, [RH, Score=462, Expect=9e-157]} {Celegans: WBGene00017472, cst-1, Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit, [RH, Score=492, Expect=5e-171]} {Smed: dd_Smed_v6_4384_0_1, dd_Smed_v6_4384_0_1, [RH, Score=479, Expect=3e-166]} {RNA1509_15462} {RNA1310_15236, RNA1509_15462} {RNA1509_15462, RNA815_5298.1} |
18. | MligTC455_42370 | 1918 | 39.97 | Mlig455_064104 | Neo: - Age: logFC(26M/2M)=-0.367 |
CAV1 | 0.951 | - | - | - | - | 0.951 | - | Mlig455_064104 {REF} {Length: 2616} {Pfam: Caveolin [PF01146.19, score=143.1]} {Human: ENSG00000105974, CAV1, caveolin 1, [RH, Score=117, Expect=4e-31]} {Mouse: ENSMUSG00000007655, Cav1, caveolin 1, caveolae protein, [RH, Score=122, Expect=4e-33]} {Celegans: WBGene00000302, cav-2, Caveolin-2, [RH, Score=77.0, Expect=1e-15]} {Smed: dd_Smed_v6_6535_0_2, dd_Smed_v6_6535_0_2, [Score=91.7, Expect=2e-22]} {RNA1509_42761} {RNA1310_10782.2} {RNA815_16688.1} |
19. | MligTC455_28596 | 52 | 1.08 | Mlig455_039629 | Neo: - Age: - |
0.95 | - | - | - | - | 0.950 | - | Mlig455_039629 {REF} {Length: 1244} {Pfam: Integrase core domain [PF00665.28, score=31.2]} {Smed: dd_Smed_v6_11155_0_2, dd_Smed_v6_11155_0_2, [Score=58.2, Expect=2e-10]} {RNA1509_21400} {RNA1310_576.1} {RNA815_2733.1} |