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Results for MligTC455_28194

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_28194 414 8.62 Mlig455_029417

Neo: -

Age: -

CLASRP Mlig455_029417 {REF} {Length: 8883} {TRANSSPLICED} {Pfam: Alternative splicing regulator [PF09750.11, score=127.5]} {Human: ENSG00000104859, CLASRP, CLK4 associating serine/arginine rich protein, [RH, Score=196, Expect=2e-53]} {Mouse: ENSMUSG00000061028, Clasrp, CLK4-associating serine/arginine rich protein, [RH, Score=199, Expect=4e-54]} {Dmel: FBgn0039215, CG6695, [RH, Score=190, Expect=5e-50]} {Celegans: WBGene00009200, F28C1.1, [RH, Score=153, Expect=1e-38]} {Smed: dd_Smed_v6_3095_0_1, dd_Smed_v6_3095_0_1, [RH, Score=244, Expect=2e-73]} {RNA1509_27971} {RNA1310_6399.1} {RNA815_1450.1}

Cumulative graph for MligTC455_28194

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 1.259 3.354 0.36023 1.00000
RegionR2 0.835 3.354 0.13971 0.46450
RegionR3 -0.216 3.354 0.70992 1.00000
RegionR4 -0.069 3.354 0.91885 1.00000
RegionR5 0.081 3.354 0.85561 1.00000
RegionR6 -0.151 3.354 0.79979 1.00000
RegionR7 -0.848 3.354 0.36963 1.00000
RegionR8 -0.891 3.354 0.52998 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.073 3.354 0.95766 1.00000
RegenerationR2 0.066 3.354 0.86367 1.00000
RegenerationR3 0.247 3.354 0.63675 0.92360
RegenerationR4 0.366 3.354 0.41796 0.82476
RegenerationR5 0.803 3.354 0.05825 0.38463
RegenerationR6 0.939 3.354 0.05851 0.30349
RegenerationBL 1.75 3.354 0.00898 0.09421
RegenerationTP 2.047 3.354 0.01552 0.21369


Genes with expression patterns similar to MligTC455_28194

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_28194 414 8.62 Mlig455_029417

Neo: -

Age: -

CLASRP 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_029417 {REF} {Length: 8883} {TRANSSPLICED} {Pfam: Alternative splicing regulator [PF09750.11, score=127.5]} {Human: ENSG00000104859, CLASRP, CLK4 associating serine/arginine rich protein, [RH, Score=196, Expect=2e-53]} {Mouse: ENSMUSG00000061028, Clasrp, CLK4-associating serine/arginine rich protein, [RH, Score=199, Expect=4e-54]} {Dmel: FBgn0039215, CG6695, [RH, Score=190, Expect=5e-50]} {Celegans: WBGene00009200, F28C1.1, [RH, Score=153, Expect=1e-38]} {Smed: dd_Smed_v6_3095_0_1, dd_Smed_v6_3095_0_1, [RH, Score=244, Expect=2e-73]} {RNA1509_27971} {RNA1310_6399.1} {RNA815_1450.1}
2. MligTC455_18386 230 4.8 Mlig455_029645

Neo: -

Age: -

DLG1 1.846 - - 0.976 - - 0.870 Mlig455_029645 {REF} {Length: 2388} {Pfam: PDZ domain [PF00595.26, score=135.7]; L27_1 [PF09058.12, score=96.1]; PDZ domain [PF17820.3, score=55.3]; PDZ domain [PF13180.8, score=32.3]} {Human: ENSG00000075711, DLG1, discs large MAGUK scaffold protein 1, [Score=259, Expect=2e-77]} {Mouse: ENSMUSG00000022770, Dlg1, discs large MAGUK scaffold protein 1, [Score=259, Expect=4e-80]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=249, Expect=9e-74]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [Score=128, Expect=1e-31]} {Smed: dd_Smed_v6_3493_1_1, dd_Smed_v6_3493_1_1, [Score=130, Expect=2e-33]} {RNA1509_30464} {RNA1310_16239, RNA1509_30464} {RNA1509_30464, RNA815_16951}
3. MligTC455_16727 150 3.13 Mlig455_001964

Neo: -

Age: -

1.817 - - 0.961 - - 0.856 Mlig455_001964 {REF} {Length: 1692} {RNA1509_60018} {RNA1310_78911} {RNA815_36932.1}
4. MligTC455_50118 194 4.04 Mlig455_041659

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.843

GIMAP4 1.801 - - 0.971 - - 0.830 Mlig455_041659 {REF} {Length: 2246} {Pfam: AIG1 family [PF04548.18, score=124.8]; Hint module [PF01079.22, score=108.5]; 50S ribosome-binding GTPase [PF01926.25, score=28.0]; ABC transporter [PF00005.29, score=19.9]; Septin [PF00735.20, score=19.2]} {Human: ENSG00000133574, GIMAP4, GTPase, IMAP family member 4, [RH, Score=103, Expect=8e-24]} {Mouse: ENSMUSG00000051124, Gimap9, GTPase, IMAP family member 9, [Score=100, Expect=3e-23]} {Dmel: FBgn0004644, hh, hedgehog, [Score=58.5, Expect=7e-09]} {Celegans: WBGene00001700, grd-11, GRounDhog (Hedgehog-like family), [Score=63.9, Expect=2e-10]} {RNA1509_25973} {RNA1310_10149, RNA1509_25973} {RNA1509_25973, RNA815_5524}
5. MligTC455_40187 270 5.62 Mlig455_049370

Neo: Irradiation

Age: Down-Up-Down, logFC(26M/2M)=0.494

1.799 - - 0.971 - - 0.828 Mlig455_049370 {REF} {Length: 5146} {TRANSSPLICED} {RNA1509_31164, RNA1509_58180} {RNA1310_1836, RNA1509_58180} {RNA1509_58180, RNA815_1211}
6. MligTC455_45300 333 6.94 Mlig455_020728

Neo: -

Age: -

1.791 - - 0.953 - - 0.838 Mlig455_020728 {REF} {Length: 4245} {Pfam: C2H2-type zinc finger [PF13894.8, score=40.5]; Zinc finger, C2H2 type [PF00096.28, score=26.8]; Cysteine rich domain with multizinc binding regions [PF17979.3, score=23.7]} {Dmel: FBgn0036725, CG18265, [RH, Score=55.5, Expect=3e-07]} {Celegans: WBGene00000995, die-1, Dorsal Intercalation and Elongation defect, [RH, Score=58.9, Expect=2e-08]} {Smed: dd_Smed_v6_34785_0_1, dd_Smed_v6_34785_0_1, [RH, Score=121, Expect=1e-28]} {RNA1509_19455} {RNA1310_2166.1, RNA1509_19455} {RNA1509_19455, RNA815_12667}
7. MligTC455_10785 347 7.24 Mlig455_030825

Neo: -

Age: -

1.758 - - 0.972 - - 0.786 Mlig455_030825 {REF} {Length: 570} {Pfam: Essential protein Yae1, N terminal [PF09811.11, score=77.3]}
8. MligTC455_40188 272 5.67 Mlig455_062295

Neo: Irradiation

Age: -

Region-enriched R5: 1.002/0.04846

1.757 - - 0.960 - - 0.797 Mlig455_062295 {REF} {Length: 5152} {TRANSSPLICED} {RNA1509_31164, RNA1509_6022} {RNA1310_1836, RNA1509_31164, RNA1509_6022} {RNA1509_31164, RNA1509_6022, RNA815_1211}
9. MligTC455_20658 197 4.11 Mlig455_038718, Mlig455_063446

Neo: -

Age: -

1.748 - - 0.963 - - 0.785

Mlig455_038718 {REF} {Length: 1687} {NoTransDecoderORF} {RNA1509_18723} {RNA1310_2938.1} {RNA815_14343.1}

Mlig455_063446 {REF} {Length: 394} {NoTransDecoderORF} {RNA1509_51071} {RNA1310_2938.1} {RNA815_14343.3}
10. MligTC455_48673 272 5.66 Mlig455_060603

Neo: -

Age: -

1.731 - - 0.971 - - 0.760 Mlig455_060603 {REF} {Length: 1614} {TRANSSPLICED} {Pfam: WW domain-binding protein 1 [PF11669.10, score=21.2]} {RNA1310_20158.1} {RNA815_24401}
11. MligTC455_37708 135 2.81 Mlig455_008316

Neo: -

Age: Down-Up-Down

1.728 0.747 - 0.981 - - - Mlig455_008316 {REF} {Length: 3405} {Pfam: NHL repeat [PF01436.23, score=45.8]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=52.4, Expect=2e-06]} {Dmel: FBgn0265356, tn, thin, [Score=58.2, Expect=2e-08]} {Celegans: WBGene00003597, nhl-1, RING finger protein nhl-1, [Score=48.5, Expect=1e-05]} {Smed: dd_Smed_v6_14782_0_1, dd_Smed_v6_14782_0_1, [Score=47.8, Expect=1e-05]} {RNA1509_45609} {RNA1310_24165, RNA1509_45609} {RNA1509_45609, RNA815_29204.1}
12. MligTC455_38987 148 3.09 Mlig455_065250

Neo: -

Age: -

1.725 - - 0.961 - - 0.764 Mlig455_065250 {REF} {Length: 1905} {RNA1509_22928} {RNA1310_43587.1} {RNA815_21673}
13. MligTC455_28884 277 5.78 Mlig455_044369

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.673

1.712 - - 0.977 - - 0.735 Mlig455_044369 {REF} {Length: 10749} {Mouse: ENSMUSG00000074358, Ccdc61, coiled-coil domain containing 61, [Score=51.2, Expect=1e-06]} {Smed: dd_Smed_v6_14065_0_1, dd_Smed_v6_14065_0_1, [Score=50.4, Expect=1e-06]} {RNA1509_18025, RNA1509_4648, RNA1509_54449} {RNA1310_2280.1, RNA1509_18025, RNA1509_54449} {RNA1509_18025, RNA1509_54449, RNA815_694.2}
14. MligTC455_25582 465 9.69 Mlig455_009721

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.797/0.02183

CHRNA3 1.705 - - 0.958 0.747 - - Mlig455_009721 {REF} {Length: 2022} {TRANSSPLICED} {Pfam: Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=280.9]; Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=264.3]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [RH, Score=455, Expect=3e-155]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [RH, Score=452, Expect=3e-154]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [RH, Score=450, Expect=3e-153]; ENSG00000147434, CHRNA6, cholinergic receptor nicotinic alpha 6 subunit, [RH, Score=445, Expect=2e-151]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [RH, Score=443, Expect=6e-149]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [RH, Score=456, Expect=8e-156]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [RH, Score=446, Expect=6e-152]; ENSMUSG00000035200, Chrnb4, cholinergic receptor, nicotinic, beta polypeptide 4, [RH, Score=439, Expect=2e-149]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [RH, Score=600, Expect=0.0]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [RH, Score=506, Expect=1e-175]} {Smed: dd_Smed_v6_14630_0_1, dd_Smed_v6_14630_0_1, [Score=468, Expect=7e-160]} {RNA1509_19239} {RNA1310_7228, RNA1509_19239} {RNA1509_19239, RNA815_134.1}
15. MligTC455_46149 747 15.56 Mlig455_023545, Mlig455_023652, Mlig455_023673

Neo: -

Age: -

COQ4 1.7 - - 0.955 - - 0.745

Mlig455_023545 {REF} {Length: 1302} {TRANSSPLICED} {Pfam: Coenzyme Q (ubiquinone) biosynthesis protein Coq4 [PF05019.15, score=259.4]} {Human: ENSG00000167113, COQ4, coenzyme Q4, [RH, Score=214, Expect=1e-68]} {Mouse: ENSMUSG00000026798, Coq4, coenzyme Q4, [RH, Score=209, Expect=2e-66]} {Dmel: FBgn0052174, CG32174, [RH, Score=201, Expect=2e-63]} {Celegans: WBGene00000764, coq-4, Ubiquinone biosynthesis protein coq-4, mitochondrial, [RH, Score=179, Expect=2e-55]} {Smed: dd_Smed_v6_8912_0_1, dd_Smed_v6_8912_0_1, [RH, Score=254, Expect=1e-84]} {RNA1509_22888, RNA1509_25136} {RNA1310_24601, RNA1509_22888} {RNA1509_22888, RNA815_12943.1}

Mlig455_023652 {REF} {Length: 1639} {TRANSSPLICED} {Pfam: Coenzyme Q (ubiquinone) biosynthesis protein Coq4 [PF05019.15, score=262.1]} {Human: ENSG00000167113, COQ4, coenzyme Q4, [RH, Score=215, Expect=9e-69]} {Mouse: ENSMUSG00000026798, Coq4, coenzyme Q4, [RH, Score=208, Expect=4e-66]} {Dmel: FBgn0052174, CG32174, [RH, Score=200, Expect=5e-63]} {Celegans: WBGene00000764, coq-4, Ubiquinone biosynthesis protein coq-4, mitochondrial, [RH, Score=179, Expect=1e-55]} {Smed: dd_Smed_v6_8912_0_1, dd_Smed_v6_8912_0_1, [RH, Score=254, Expect=2e-84]} {RNA1509_25136} {RNA1310_24601, RNA1509_25136} {RNA1509_25136, RNA815_12943.1}

Mlig455_023673 {REF} {Length: 1073} {TRANSSPLICED} {Pfam: Coenzyme Q (ubiquinone) biosynthesis protein Coq4 [PF05019.15, score=163.0]} {Human: ENSG00000167113, COQ4, coenzyme Q4, [Score=140, Expect=2e-40]} {Mouse: ENSMUSG00000026798, Coq4, coenzyme Q4, [Score=144, Expect=7e-42]} {Dmel: FBgn0052174, CG32174, [Score=130, Expect=8e-37]} {Celegans: WBGene00000764, coq-4, Ubiquinone biosynthesis protein coq-4, mitochondrial, [Score=115, Expect=2e-31]} {Smed: dd_Smed_v6_8912_0_1, dd_Smed_v6_8912_0_1, [Score=171, Expect=1e-52]} {RNA1509_25136} {RNA1310_24601} {RNA815_12943.1}
16. MligTC455_38471 616 12.83 Mlig455_039751

Neo: -

Age: Down-Up-Down

KIF3A 1.696 - - 0.964 0.732 - - Mlig455_039751 {REF} {Length: 3329} {TRANSSPLICED} {Pfam: Kinesin motor domain [PF00225.25, score=390.5]; Microtubule binding [PF16796.7, score=88.9]} {Human: ENSG00000131437, KIF3A, kinesin family member 3A, [RH, Score=827, Expect=0.0]} {Mouse: ENSMUSG00000018395, Kif3a, kinesin family member 3A, [RH, Score=802, Expect=0.0]} {Dmel: FBgn0004380, Klp64D, Kinesin-like protein at 64D, [RH, Score=645, Expect=0.0]} {Celegans: WBGene00002230, klp-20, Kinesin-like protein, [RH, Score=628, Expect=0.0]} {Smed: dd_Smed_v6_4343_0_1, dd_Smed_v6_4343_0_1, [Score=682, Expect=0.0]} {RNA1509_4278, RNA1509_43523} {RNA1310_9183.2, RNA1509_43523} {RNA1509_43523, RNA815_3246}
17. MligTC455_49267 1108 23.08 Mlig455_014279, Mlig455_014314, Mlig455_014331

Neo: -

Age: Down-Up-Up

Region-enriched R7: 1.758/0.00078

1.683 - - 0.952 - - 0.731

Mlig455_014279 {REF} {Length: 976} {RNA1509_49320} {RNA1310_72049} {RNA815_23076}

Mlig455_014314 {REF} {Length: 976} {RNA1509_49320} {RNA1310_72049} {RNA815_23076}

Mlig455_014331 {REF} {Length: 998} {RNA1509_49320} {RNA1310_72049, RNA1509_49320} {RNA1509_49320, RNA815_23076}
18. MligTC455_43034 470 9.79 Mlig455_009703

Neo: -

Age: -

1.674 - - 0.972 - - 0.702 Mlig455_009703 {REF} {Length: 4741} {Pfam: NHL repeat [PF01436.23, score=34.6]} {Dmel: FBgn0265356, tn, thin, [Score=53.9, Expect=2e-07]} {RNA1509_22989} {RNA1310_8201.1, RNA1509_22989} {RNA1509_22989, RNA815_27967}
19. MligTC455_28517 169 3.52 Mlig455_032503

Neo: -

Age: -

1.669 0.709 - 0.960 - - - Mlig455_032503 {REF} {Length: 728} {NoTransDecoderORF} {RNA1310_54604.1} {RNA815_39231}
20. MligTC455_30637 399 8.31 Mlig455_018213, Mlig455_026001, Mlig455_040474, Mlig455_042280, Mlig455_050687

Neo: -

Age: Up-Down-Down

1.667 - - 0.964 0.703 - -

Mlig455_018213 {REF} {Length: 5125} {RNA1509_35277} {RNA1310_5326.1} {RNA815_2615}

Mlig455_026001 {REF} {Length: 3471} {TRANSSPLICED} {RNA1509_35277} {RNA1310_5326.1} {RNA815_2615}

Mlig455_040474 {REF} {Length: 2270} {Pfam: Procyclic acidic repetitive protein (PARP) [PF05887.13, score=21.2]} {RNA1509_35277} {RNA1310_5326.1} {RNA815_2615}

Mlig455_042280 {REF} {Length: 3528} {Pfam: Procyclic acidic repetitive protein (PARP) [PF05887.13, score=21.2]} {RNA1509_35277} {RNA1310_5326.1, RNA1509_35277} {RNA1509_35277, RNA815_2615}

Mlig455_050687 {REF} {Length: 2491} {TRANSSPLICED} {RNA1509_35277} {RNA1310_5326.1} {RNA815_2615}
21. MligTC455_42679 1362 28.37 Mlig455_034910

Neo: -

Age: Down-Up-Down

1.661 - - 0.704 - - 0.957 Mlig455_034910 {REF} {Length: 1350} {NoTransDecoderORF} {RNA1509_38066, RNA1509_46870} {RNA1310_24331.1, RNA1509_38066, RNA1509_46870} {RNA1509_38066, RNA1509_46870, RNA815_10810.1}
22. MligTC455_16014 135 2.81 Mlig455_057808

Neo: -

Age: -

SLC6A3 0.989 - - 0.989 - - - Mlig455_057808 {REF} {Length: 3595} {tRNA: Undet(NNN),pseudo, score=28.6} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=586.5]} {Human: ENSG00000142319, SLC6A3, solute carrier family 6 member 3, [Score=521, Expect=1e-177]; ENSG00000276996, SLC6A3, solute carrier family 6 member 3, [Score=521, Expect=1e-177]; ENSG00000103546, SLC6A2, solute carrier family 6 member 2, [Score=505, Expect=1e-171]} {Mouse: ENSMUSG00000021609, Slc6a3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, [Score=523, Expect=1e-178]; ENSMUSG00000055368, Slc6a2, solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2, [Score=511, Expect=3e-174]} {Dmel: FBgn0010414, SerT, Serotonin transporter, [Score=468, Expect=2e-157]} {Celegans: WBGene00000934, dat-1, Sodium-dependent dopamine transporter, [Score=433, Expect=4e-144]} {Smed: dd_Smed_v6_22486_0_1, dd_Smed_v6_22486_0_1, [RH, Score=571, Expect=0.0]} {RNA1509_41282} {RNA1310_11169, RNA1509_41282} {RNA1509_41282, RNA815_3966}
23. MligTC455_27957 80 1.67 Mlig455_063329

Neo: -

Age: Down-Down-Down

0.988 - - 0.988 - - - Mlig455_063329 {REF} {Length: 941} {RNA1509_9468} {RNA1310_75716} {RNA815_18818.1}
24. MligTC455_37393 35 0.73 Mlig455_013701

Neo: -

Age: logFC(26M/2M)=-0.517

MAP3K19 0.985 - - 0.985 - - - Mlig455_013701 {REF} {Length: 3160} {Pfam: Protein kinase domain [PF00069.27, score=137.4]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.5]; ABC1 atypical kinase-like domain [PF03109.18, score=27.0]; Seadornavirus VP7 [PF07387.13, score=18.5]} {Human: ENSG00000176601, MAP3K19, mitogen-activated protein kinase kinase kinase 19, [Score=104, Expect=2e-22]; ENSG00000011566, MAP4K3, mitogen-activated protein kinase kinase kinase kinase 3, [Score=100, Expect=3e-21]; ENSG00000134602, STK26, serine/threonine kinase 26, [Score=99.4, Expect=7e-22]} {Mouse: ENSMUSG00000051590, Map3k19, mitogen-activated protein kinase kinase kinase 19, [Score=105, Expect=8e-23]; ENSMUSG00000024242, Map4k3, mitogen-activated protein kinase kinase kinase kinase 3, [Score=100, Expect=2e-21]} {Dmel: FBgn0266465, GckIII, Germinal centre kinase III, [Score=100, Expect=1e-21]} {Celegans: WBGene00022603, gck-2, Mitogen-activated protein kinase kinase kinase kinase, [Score=105, Expect=2e-23]} {Smed: dd_Smed_v6_9984_0_1, dd_Smed_v6_9984_0_1, [Score=101, Expect=2e-23]} {RNA1509_11136} {RNA1310_29101} {RNA815_16478}
25. MligTC455_37394 43 0.89 Mlig455_013716

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.606

STK26 0.985 - - 0.985 - - - Mlig455_013716 {REF} {Length: 3206} {Pfam: Protein kinase domain [PF00069.27, score=84.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=58.2]; Ankyrin repeats (many copies) [PF13637.8, score=54.2]; Ankyrin repeats (3 copies) [PF12796.9, score=51.9]; Ankyrin repeats (many copies) [PF13857.8, score=34.6]; Ankyrin repeat [PF13606.8, score=34.0]; Ankyrin repeat [PF00023.32, score=23.7]} {Human: ENSG00000134602, STK26, serine/threonine kinase 26, [Score=65.9, Expect=7e-11]; ENSG00000065613, SLK, STE20 like kinase, [Score=65.1, Expect=4e-10]; ENSG00000166963, MAP1A, microtubule associated protein 1A, [Score=65.1, Expect=4e-10]; ENSG00000137601, NEK1, NIMA related kinase 1, [Score=64.3, Expect=7e-10]; ENSG00000132155, RAF1, Raf-1 proto-oncogene, serine/threonine kinase, [Score=64.3, Expect=5e-10]; ENSG00000126562, WNK4, WNK lysine deficient protein kinase 4, [Score=63.5, Expect=1e-09]} {Mouse: ENSMUSG00000031644, Nek1, NIMA (never in mitosis gene a)-related expressed kinase 1, [Score=65.1, Expect=3e-10]; ENSMUSG00000031112, Stk26, serine/threonine kinase 26, [Score=64.7, Expect=2e-10]; ENSMUSG00000025060, Slk, STE20-like kinase, [Score=64.3, Expect=5e-10]; ENSMUSG00000000441, Raf1, v-raf-leukemia viral oncogene 1, [Score=63.9, Expect=5e-10]; ENSMUSG00000035112, Wnk4, WNK lysine deficient protein kinase 4, [Score=63.2, Expect=1e-09]} {Dmel: FBgn0031299, CG4629, [Score=56.2, Expect=7e-08]} {Celegans: WBGene00006941, wnk-1, Serine/threonine-protein kinase WNK, [Score=54.3, Expect=3e-07]} {Smed: dd_Smed_v6_1196_0_1, dd_Smed_v6_1196_0_1, [Score=51.2, Expect=7e-07]} {RNA1509_11136} {RNA1310_29101} {RNA815_16478}
26. MligTC455_21489 151 3.14 Mlig455_037060

Neo: -

Age: -

0.984 - - 0.984 - - - Mlig455_037060 {REF} {Length: 3821} {RNA1509_15558, RNA1509_33016, RNA1509_53978} {RNA1310_11910.1, RNA1509_15558, RNA1509_33016, RNA1509_53978} {RNA1509_15558, RNA1509_33016, RNA1509_53978, RNA815_5242}
27. MligTC455_15591 300 6.24 Mlig455_023510

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.498

0.982 - - 0.982 - - - Mlig455_023510 {REF} {Length: 2487} {TRANSSPLICED} {Pfam: Interferon-regulatory factor 3 [PF10401.11, score=31.4]; Interferon regulatory factor transcription factor [PF00605.19, score=30.0]} {RNA1509_19195} {RNA1310_22732} {RNA815_9876}
28. MligTC455_04788 1208 25.17 Mlig455_023502, Mlig455_023613

Neo: -

Age: -

CTU2 0.981 - - 0.981 - - -

Mlig455_023502 {REF} {Length: 2980} {TRANSSPLICED} {Pfam: Cytoplasmic tRNA 2-thiolation protein 2 [PF10288.11, score=44.1]} {Human: ENSG00000174177, CTU2, cytosolic thiouridylase subunit 2, [RH, Score=78.2, Expect=6e-15]} {Mouse: ENSMUSG00000049482, Ctu2, cytosolic thiouridylase subunit 2, [RH, Score=69.3, Expect=3e-12]} {Dmel: FBgn0032793, CG10189, [RH, Score=77.8, Expect=2e-15]} {Smed: dd_Smed_v6_8468_0_1, dd_Smed_v6_8468_0_1, [RH, Score=131, Expect=2e-34]} {RNA1509_20294, RNA1509_28583} {RNA1310_18692, RNA1509_28583} {RNA1509_28583, RNA815_10751}

Mlig455_023613 {REF} {Length: 3288} {TRANSSPLICED} {Pfam: Cytoplasmic tRNA 2-thiolation protein 2 [PF10288.11, score=44.1]} {Human: ENSG00000174177, CTU2, cytosolic thiouridylase subunit 2, [RH, Score=78.2, Expect=6e-15]} {Mouse: ENSMUSG00000049482, Ctu2, cytosolic thiouridylase subunit 2, [RH, Score=69.3, Expect=3e-12]} {Dmel: FBgn0032793, CG10189, [RH, Score=77.8, Expect=2e-15]} {Smed: dd_Smed_v6_8468_0_1, dd_Smed_v6_8468_0_1, [RH, Score=131, Expect=2e-34]} {RNA1509_20294} {RNA1310_18692} {RNA815_10751}
29. MligTC455_27897 128 2.66 Mlig455_012952, Mlig455_012961

Neo: -

Age: -

0.981 - - 0.981 - - -

Mlig455_012952 {REF} {Length: 2131} {Pfam: Protein of unknown function (DUF1180) [PF06679.14, score=20.2]; Family of unknown function (DUF6491) [PF20101.1, score=18.6]} {RNA1509_2412} {RNA1310_41742} {RNA815_21822}

Mlig455_012961 {REF} {Length: 2277} {Pfam: Protein of unknown function (DUF1180) [PF06679.14, score=20.2]; Family of unknown function (DUF6491) [PF20101.1, score=19.4]} {RNA1509_2412} {RNA1310_41742} {RNA815_21822}
30. MligTC455_52032 733 15.27 Mlig455_049281, Mlig455_049292

Neo: -

Age: -

Region-enriched R2: 1.871/0.03166

PPIL6 0.979 - - 0.979 - - -

Mlig455_049281 {REF} {Length: 1491} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=138.3]} {Human: ENSG00000185250, PPIL6, peptidylprolyl isomerase like 6, [RH, Score=278, Expect=2e-92]} {Mouse: ENSMUSG00000078451, Ppil6, peptidylprolyl isomerase (cyclophilin)-like 6, [RH, Score=267, Expect=2e-88]} {Dmel: FBgn0036415, CG7768, [Score=153, Expect=7e-46]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=174, Expect=4e-54]} {Smed: dd_Smed_v6_10327_0_1, dd_Smed_v6_10327_0_1, [RH, Score=200, Expect=1e-64]} {RNA1509_38880, RNA1509_54777, RNA1509_5736} {RNA1310_29201, RNA1509_38880, RNA1509_54777} {RNA1509_38880, RNA1509_54777, RNA815_16054}

Mlig455_049292 {REF} {Length: 1337} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=143.4]} {Human: ENSG00000185250, PPIL6, peptidylprolyl isomerase like 6, [RH, Score=256, Expect=1e-84]} {Mouse: ENSMUSG00000078451, Ppil6, peptidylprolyl isomerase (cyclophilin)-like 6, [Score=253, Expect=5e-83]} {Dmel: FBgn0036415, CG7768, [Score=159, Expect=1e-48]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=179, Expect=2e-56]} {Smed: dd_Smed_v6_10327_0_1, dd_Smed_v6_10327_0_1, [RH, Score=203, Expect=3e-66]} {RNA1509_5736} {RNA1310_29201, RNA1509_5736} {RNA1509_5736, RNA815_16054}
31. MligTC455_52033 531 11.05 Mlig455_050626

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.538

Region-enriched R2: 1.855/0.01555

PPIL6 0.979 - - 0.979 - - - Mlig455_050626 {REF} {Length: 1572} {TRANSSPLICED} {Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD [PF00160.23, score=143.3]} {Human: ENSG00000185250, PPIL6, peptidylprolyl isomerase like 6, [RH, Score=278, Expect=2e-92]} {Mouse: ENSMUSG00000078451, Ppil6, peptidylprolyl isomerase (cyclophilin)-like 6, [RH, Score=266, Expect=4e-88]} {Dmel: FBgn0036415, CG7768, [Score=160, Expect=1e-48]} {Celegans: WBGene00000883, cyn-7, Peptidyl-prolyl cis-trans isomerase 7, [Score=181, Expect=1e-56]} {Smed: dd_Smed_v6_10327_0_1, dd_Smed_v6_10327_0_1, [RH, Score=205, Expect=1e-66]} {RNA1509_5736} {RNA1310_29201} {RNA815_16054}
32. MligTC455_33544 1102 22.96 Mlig455_048665, Mlig455_051625

Neo: -

Age: -

ANK1 0.978 - - 0.978 - - -

Mlig455_048665 {REF} {Length: 6687} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=471.4]; Ankyrin repeats (many copies) [PF13637.8, score=407.7]; Ankyrin repeat [PF13606.8, score=360.6]; Ankyrin repeat [PF00023.32, score=340.5]; Ankyrin repeats (many copies) [PF13857.8, score=334.7]; Saccharopine dehydrogenase NADP binding domain [PF03435.20, score=20.2]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=266, Expect=8e-72]; ENSG00000145362, ANK2, ankyrin 2, [Score=264, Expect=6e-71]; ENSG00000151150, ANK3, ankyrin 3, [Score=260, Expect=5e-70]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=257, Expect=6e-69]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=257, Expect=3e-70]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=280, Expect=2e-76]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=257, Expect=1e-70]} {Smed: dd_Smed_v6_13156_0_1, dd_Smed_v6_13156_0_1, [RH, Score=758, Expect=0.0]} {RNA1509_11632, RNA1509_22733, RNA1509_50693, RNA1509_7759} {RNA1310_2064, RNA1509_11632, RNA1509_22733, RNA1509_50693, RNA1509_7759} {RNA1509_11632, RNA1509_22733, RNA1509_50693, RNA1509_7759, RNA815_679.1}

Mlig455_051625 {REF} {Length: 5509} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=216.9]; Ankyrin repeats (many copies) [PF13857.8, score=185.6]; Ankyrin repeats (many copies) [PF13637.8, score=181.1]; Ankyrin repeat [PF00023.32, score=179.0]; Ankyrin repeat [PF13606.8, score=171.9]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=180, Expect=2e-48]; ENSG00000145362, ANK2, ankyrin 2, [Score=175, Expect=1e-46]; ENSG00000151150, ANK3, ankyrin 3, [Score=174, Expect=3e-46]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=177, Expect=1e-47]; ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=172, Expect=6e-46]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=193, Expect=5e-53]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=182, Expect=1e-49]} {Smed: dd_Smed_v6_13156_0_1, dd_Smed_v6_13156_0_1, [Score=473, Expect=2e-155]} {RNA1509_50211, RNA1509_7759} {RNA1310_2064, RNA1509_50211} {RNA1509_50211, RNA815_679.1}
33. MligTC455_47286 289 6.03 Mlig455_046903

Neo: -

Age: -

A4GNT 0.978 - - 0.978 - - - Mlig455_046903 {REF} {Length: 4660} {Pfam: Glycosyltransferase sugar-binding region containing DXD motif [PF04488.17, score=67.9]; Capsular polysaccharide synthesis protein [PF05704.14, score=26.6]; TcdA/TcdB catalytic glycosyltransferase domain [PF12919.9, score=21.6]} {Human: ENSG00000118017, A4GNT, alpha-1,4-N-acetylglucosaminyltransferase, [RH, Score=48.9, Expect=6e-06]} {Mouse: ENSMUSG00000037953, A4gnt, alpha-1,4-N-acetylglucosaminyltransferase, [RH, Score=49.7, Expect=3e-06]} {Smed: dd_Smed_v6_11922_0_1, dd_Smed_v6_11922_0_1, [Score=137, Expect=2e-37]} {RNA1509_36804} {RNA1310_21577.1, RNA1509_36804} {RNA1509_36804, RNA815_8725.1}
34. MligTC455_27422 441 9.18 Mlig455_040999

Neo: -

Age: -

ATF7 0.977 - - - - - 0.977 Mlig455_040999 {REF} {Length: 3724} {TRANSSPLICED} {Pfam: bZIP transcription factor [PF00170.23, score=30.3]; Basic region leucine zipper [PF07716.17, score=24.9]; Phlebovirus nonstructural protein NS-M [PF07246.13, score=24.6]; bZIP Maf transcription factor [PF03131.19, score=22.6]} {Human: ENSG00000170653, ATF7, activating transcription factor 7, [Score=73.6, Expect=3e-13]; ENSG00000267281, AC023509.3, novel protein, [Score=73.2, Expect=4e-13]; ENSG00000115966, ATF2, activating transcription factor 2, [Score=72.8, Expect=6e-13]; ENSG00000146592, CREB5, cAMP responsive element binding protein 5, [Score=70.1, Expect=3e-12]} {Mouse: ENSMUSG00000099083, Atf7, activating transcription factor 7, [Score=73.6, Expect=2e-13]; ENSMUSG00000052414, Gm28047, predicted gene, 28047, [Score=72.4, Expect=5e-13]; ENSMUSG00000027104, Atf2, activating transcription factor 2, [Score=72.0, Expect=7e-13]} {Dmel: FBgn0265784, CrebB, Cyclic-AMP response element binding protein B, [Score=50.4, Expect=3e-06]} {Celegans: WBGene00000793, crh-1, CREB Homolog; Cyclic AMP-response element binding protein 1 gamma 2, [Score=55.8, Expect=5e-08]} {RNA1509_19991, RNA1509_49323} {RNA1310_14708, RNA1509_19991, RNA1509_49323} {RNA1509_19991, RNA1509_49323, RNA815_18843.1}
35. MligTC455_10203 1017 21.19 Mlig455_011493

Neo: -

Age: logFC(26M/2M)=-0.361

RALA 0.975 - - 0.975 - - - Mlig455_011493 {REF} {Length: 1764} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=45.7]} {Human: ENSG00000006451, RALA, RAS like proto-oncogene A, [Score=97.1, Expect=1e-25]} {Mouse: ENSMUSG00000008859, Rala, v-ral simian leukemia viral oncogene A (ras related), [Score=96.7, Expect=9e-26]} {Dmel: FBgn0015286, Rala, Ras-like protein A, [Score=97.4, Expect=3e-26]} {Celegans: WBGene00021811, ral-1, RAL (Ras-related GTPase) homolog, [Score=86.7, Expect=5e-22]} {Smed: dd_Smed_v6_522_0_1, dd_Smed_v6_522_0_1, [Score=79.7, Expect=1e-19]} {RNA1509_18505} {RNA1310_31938} {RNA815_13414.1}
36. MligTC455_13858 171 3.56 Mlig455_018105, Mlig455_018109, Mlig455_021980, Mlig455_021996, Mlig455_029083, Mlig455_070484

Neo: -

Age: Up-Down-Up

0.975 - - 0.975 - - -

Mlig455_018105 {REF} {Length: 482} {NoTransDecoderORF} {RNA1509_40709} {RNA1310_18972} {RNA815_34163}

Mlig455_018109 {REF} {Length: 368} {NoTransDecoderORF} {RNA1509_40709} {RNA1310_18972} {RNA815_34163}

Mlig455_021980 {REF} {Length: 482} {NoTransDecoderORF} {RNA1509_40709} {RNA1310_18972} {RNA815_34163}

Mlig455_021996 {REF} {Length: 796} {NoTransDecoderORF} {RNA1509_40709} {RNA1310_18972} {RNA815_34163}

Mlig455_029083 {REF} {Length: 532} {NoTransDecoderORF} {RNA1509_40709} {RNA1310_83600} {RNA815_18763.1}

Mlig455_070484 {REF} {Length: 3985} {NoTransDecoderORF} {RNA1509_40709} {RNA1310_18972} {RNA815_18763.1}
37. MligTC455_28860 122 2.54 Mlig455_026196

Neo: -

Age: -

SAXO1 0.972 - - 0.972 - - - Mlig455_026196 {REF} {Length: 2909} {Pfam: STOP protein [PF05217.14, score=21.7]} {Human: ENSG00000155875, SAXO1, stabilizer of axonemal microtubules 1, [Score=198, Expect=3e-57]} {Mouse: ENSMUSG00000038570, Saxo2, stabilizer of axonemal microtubules 2, [RH, Score=179, Expect=4e-51]} {Celegans: WBGene00011630, T08G11.3, [RH, Score=86.7, Expect=7e-18]} {Smed: dd_Smed_v6_3695_0_1, dd_Smed_v6_3695_0_1, [Score=415, Expect=9e-142]} {RNA1509_41580, RNA1509_52585} {RNA1310_10851.2, RNA1509_41580, RNA1509_52585} {RNA1509_41580, RNA1509_52585, RNA815_5931.1}
38. MligTC455_31405 1547 32.24 Mlig455_021385

Neo: -

Age: Up-Down-Up

0.972 - - 0.972 - - - Mlig455_021385 {REF} {Length: 3364} {Pfam: Laminin EGF domain [PF00053.26, score=19.5]} {RNA1509_23420, RNA1509_24108, RNA1509_25322} {RNA1310_22595.1, RNA1509_23420, RNA1509_24108, RNA1509_25322} {RNA1509_23420, RNA1509_24108, RNA1509_25322, RNA815_9317}
39. MligTC455_38448 390 8.12 Mlig455_064678

Neo: -

Age: Down-Down-Up

0.972 - - 0.972 - - - Mlig455_064678 {REF} {Length: 2178} {TRANSSPLICED} {Pfam: PH domain [PF00169.31, score=33.8]} {Dmel: FBgn0263353, CG11000, [RH, Score=68.6, Expect=1e-12]} {Celegans: WBGene00009534, F38B7.3, [RH, Score=82.4, Expect=5e-17]} {Smed: dd_Smed_v6_4018_0_1, dd_Smed_v6_4018_0_1, [RH, Score=118, Expect=8e-30]} {RNA1509_10365} {RNA1310_20310, RNA1509_10365} {RNA1509_10365, RNA815_26365}
40. MligTC455_39672 865 18.02 Mlig455_031961, Mlig455_032012

Neo: -

Age: -

RAP1B, RAP2B 0.972 - - 0.972 - - -

Mlig455_031961 {REF} {Length: 1982} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=181.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=69.5]; ADP-ribosylation factor family [PF00025.23, score=38.0]; RsgA GTPase [PF03193.18, score=26.2]; 50S ribosome-binding GTPase [PF01926.25, score=21.7]} {Human: ENSG00000127314, RAP1B, RAP1B, member of RAS oncogene family, [Score=212, Expect=2e-70]; ENSG00000181467, RAP2B, RAP2B, member of RAS oncogene family, [Score=212, Expect=2e-70]; ENSG00000116473, RAP1A, RAP1A, member of RAS oncogene family, [Score=207, Expect=3e-68]; ENSG00000123728, RAP2C, RAP2C, member of RAS oncogene family, [Score=207, Expect=2e-68]; ENSG00000125249, RAP2A, RAP2A, member of RAS oncogene family, [Score=204, Expect=3e-67]} {Mouse: ENSMUSG00000051615, Rap2a, RAS related protein 2a, [Score=213, Expect=5e-71]; ENSMUSG00000052681, Rap1b, RAS related protein 1b, [Score=212, Expect=2e-70]; ENSMUSG00000036894, Rap2b, RAP2B, member of RAS oncogene family, [Score=212, Expect=1e-70]; ENSMUSG00000050029, Rap2c, RAP2C, member of RAS oncogene family, [Score=207, Expect=1e-68]; ENSMUSG00000068798, Rap1a, RAS-related protein 1a, [Score=207, Expect=2e-68]} {Dmel: FBgn0004636, Rap1, Rap1 GTPase, [Score=206, Expect=3e-68]} {Celegans: WBGene00004308, rap-2, RAP homolog (Vertebrate Rap GTPase family), [Score=220, Expect=7e-74]} {Smed: dd_Smed_v6_1239_0_1, dd_Smed_v6_1239_0_1, [Score=204, Expect=6e-68]} {RNA1509_32276} {RNA1310_2841} {RNA815_8102}

Mlig455_032012 {REF} {Length: 1925} {Pfam: Ras family [PF00071.24, score=185.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.2]; ADP-ribosylation factor family [PF00025.23, score=38.3]; RsgA GTPase [PF03193.18, score=26.7]; 50S ribosome-binding GTPase [PF01926.25, score=21.4]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.7]} {Human: ENSG00000181467, RAP2B, RAP2B, member of RAS oncogene family, [Score=214, Expect=4e-71]; ENSG00000127314, RAP1B, RAP1B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSG00000123728, RAP2C, RAP2C, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000116473, RAP1A, RAP1A, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000125249, RAP2A, RAP2A, member of RAS oncogene family, [Score=206, Expect=4e-68]} {Mouse: ENSMUSG00000051615, Rap2a, RAS related protein 2a, [Score=215, Expect=7e-72]; ENSMUSG00000036894, Rap2b, RAP2B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSMUSG00000052681, Rap1b, RAS related protein 1b, [Score=214, Expect=2e-71]; ENSMUSG00000050029, Rap2c, RAP2C, member of RAS oncogene family, [Score=209, Expect=2e-69]; ENSMUSG00000068798, Rap1a, RAS-related protein 1a, [Score=209, Expect=3e-69]} {Dmel: FBgn0004636, Rap1, Rap1 GTPase, [Score=208, Expect=4e-69]} {Celegans: WBGene00004308, rap-2, RAP homolog (Vertebrate Rap GTPase family), [RH, Score=222, Expect=1e-74]} {Smed: dd_Smed_v6_1239_0_1, dd_Smed_v6_1239_0_1, [Score=207, Expect=9e-69]} {RNA1509_32276} {RNA1310_2841, RNA1509_32276} {RNA1509_32276, RNA815_8102}
41. MligTC455_31805 747 15.56 Mlig455_070318

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.499

EFCAB6 0.971 - - 0.971 - - - Mlig455_070318 {REF} {Length: 3714} {Pfam: EF-hand domain pair [PF13499.8, score=82.4]; EF-hand domain [PF08976.13, score=72.0]; EF-hand domain pair [PF13833.8, score=64.0]; EF-hand domain [PF13405.8, score=56.9]; EF hand [PF00036.34, score=53.2]; EF-hand domain [PF14658.8, score=34.9]; Family of unknown function (DUF5580) [PF17743.3, score=27.9]; EF hand [PF13202.8, score=22.4]} {Human: ENSG00000186976, EFCAB6, EF-hand calcium binding domain 6, [Score=86.3, Expect=2e-16]} {Mouse: ENSMUSG00000022441, Efcab6, EF-hand calcium binding domain 6, [Score=76.6, Expect=1e-13]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=48.9, Expect=2e-06]} {Celegans: WBGene00017394, cal-8, CALmodulin related genes, [Score=50.8, Expect=4e-07]} {Smed: dd_Smed_v6_20435_0_1, dd_Smed_v6_20435_0_1, [Score=157, Expect=1e-40]} {RNA1509_7148} {RNA1310_3069.1} {RNA815_3758}
42. MligTC455_43733 869 18.1 Mlig455_034271, Mlig455_034309

Neo: -

Age: Down-Up-Up

0.971 - - 0.971 - - -

Mlig455_034271 {REF} {Length: 2291} {Pfam: Protein kinase domain [PF00069.27, score=27.1]} {RNA1509_10827} {RNA1310_17438} {RNA815_7916}

Mlig455_034309 {REF} {Length: 2300} {RNA1509_10827} {RNA1310_9412} {RNA815_7916}
43. MligTC455_43734 871 18.15 Mlig455_067307, Mlig455_067323

Neo: -

Age: logFC(26M/2M)=-0.518

SIK3 0.971 - - 0.971 - - -

Mlig455_067307 {REF} {Length: 3849} {Pfam: Protein kinase domain [PF00069.27, score=49.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=24.7]} {Human: ENSG00000160584, SIK3, SIK family kinase 3, [Score=71.6, Expect=3e-12]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=70.5, Expect=5e-12]} {Mouse: ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=70.5, Expect=4e-12]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=70.1, Expect=5e-12]} {Dmel: FBgn0025625, Sik2, Salt-inducible kinase 2, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00006814, unc-82, [Score=61.6, Expect=2e-09]} {Smed: dd_Smed_v6_5124_0_2, dd_Smed_v6_5124_0_2, [Score=68.6, Expect=8e-12]} {RNA1509_10827} {RNA1310_9412, RNA1509_10827} {RNA1509_10827, RNA815_7916}

Mlig455_067323 {REF} {Length: 2835} {Pfam: Protein kinase domain [PF00069.27, score=49.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=24.7]} {Human: ENSG00000160584, SIK3, SIK family kinase 3, [Score=71.6, Expect=3e-12]; ENSG00000007047, MARK4, microtubule affinity regulating kinase 4, [Score=70.5, Expect=5e-12]} {Mouse: ENSMUSG00000034135, Sik3, SIK family kinase 3, [Score=70.5, Expect=4e-12]; ENSMUSG00000030397, Mark4, MAP/microtubule affinity regulating kinase 4, [Score=70.1, Expect=5e-12]} {Dmel: FBgn0025625, Sik2, Salt-inducible kinase 2, [Score=61.6, Expect=2e-09]} {Celegans: WBGene00006814, unc-82, [Score=61.6, Expect=2e-09]} {Smed: dd_Smed_v6_5124_0_2, dd_Smed_v6_5124_0_2, [Score=68.6, Expect=8e-12]} {RNA1509_10827} {RNA1310_9412} {RNA815_7916}
44. MligTC455_35252 223 4.64 Mlig455_010644

Neo: -

Age: -

Region-enriched R5: 1.599/0.03281

TDRKH 0.97 - - - - - 0.970 Mlig455_010644 {REF} {Length: 5610} {TRANSSPLICED} {Pfam: KH domain [PF00013.31, score=97.0]; Tudor domain [PF00567.26, score=57.7]; KH domain [PF07650.19, score=23.0]; DASH complex subunit Hsk3 like [PF08227.13, score=20.8]} {Human: ENSG00000182134, TDRKH, tudor and KH domain containing, [Score=92.4, Expect=2e-19]} {Mouse: ENSMUSG00000041912, Tdrkh, tudor and KH domain containing protein, [Score=85.5, Expect=2e-17]} {Dmel: FBgn0031401, papi, [Score=103, Expect=2e-23]} {Celegans: WBGene00019692, M01A10.1, [Score=48.5, Expect=7e-06]} {Smed: dd_Smed_v6_3961_0_1, dd_Smed_v6_3961_0_1, [RH, Score=141, Expect=5e-37]} {RNA1509_14606, RNA1509_51583} {RNA1310_28806.1, RNA1509_51583} {RNA1509_51583, RNA815_7454}
45. MligTC455_53021 248 5.17 Mlig455_039734, Mlig455_060892

Neo: -

Age: Down-Down-Up

0.97 - - 0.970 - - -

Mlig455_039734 {REF} {Length: 1487} {TRANSSPLICED} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}

Mlig455_060892 {REF} {Length: 3436} {RNA1509_24093} {RNA1310_26642} {RNA815_14301}
46. MligTC455_29192 53 1.11 Mlig455_016518

Neo: -

Age: -

0.968 - - 0.968 - - - Mlig455_016518 {REF} {Length: 5343} {Pfam: Procyclic acidic repetitive protein (PARP) [PF05887.13, score=21.0]} {Dmel: FBgn0029807, CG3108, [Score=57.4, Expect=1e-09]} {RNA1509_9867} {RNA1310_554.1} {RNA815_212.1}
47. MligTC455_15592 549 11.44 Mlig455_023519, Mlig455_023621

Neo: -

Age: -

IRF8 0.967 - - 0.967 - - -

Mlig455_023519 {REF} {Length: 3145} {Pfam: Interferon regulatory factor transcription factor [PF00605.19, score=52.6]; Interferon-regulatory factor 3 [PF10401.11, score=30.7]} {Human: ENSG00000140968, IRF8, interferon regulatory factor 8, [Score=50.1, Expect=8e-06]} {Mouse: ENSMUSG00000041515, Irf8, interferon regulatory factor 8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_6636_0_1, dd_Smed_v6_6636_0_1, [RH, Score=69.7, Expect=2e-12]} {RNA1509_19195} {RNA1310_22732} {RNA815_9876}

Mlig455_023621 {REF} {Length: 2477} {TRANSSPLICED} {Pfam: Interferon regulatory factor transcription factor [PF00605.19, score=52.6]; Interferon-regulatory factor 3 [PF10401.11, score=30.7]} {Human: ENSG00000140968, IRF8, interferon regulatory factor 8, [Score=50.1, Expect=8e-06]} {Mouse: ENSMUSG00000041515, Irf8, interferon regulatory factor 8, [Score=48.9, Expect=1e-05]} {Smed: dd_Smed_v6_6636_0_1, dd_Smed_v6_6636_0_1, [RH, Score=69.7, Expect=2e-12]} {RNA1509_19195} {RNA1310_22732} {RNA815_9876}
48. MligTC455_26164 170 3.54 Mlig455_013776

Neo: -

Age: -

0.967 - - 0.967 - - - Mlig455_013776 {REF} {Length: 1666} {RNA1509_56028} {RNA1310_25129} {RNA815_10685.1}
49. MligTC455_27298 94 1.95 Mlig455_050684

Neo: -

Age: -

0.967 - - 0.967 - - - Mlig455_050684 {REF} {Length: 282} {NoTransDecoderORF} {RNA1509_45642} {RNA1310_133889}
50. MligTC455_31550 339 7.07 Mlig455_057441

Neo: -

Age: -

RBM10 0.967 - - 0.967 - - - Mlig455_057441 {REF} {Length: 3693} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=48.9]; OCRE domain [PF17780.3, score=47.3]; G-patch domain [PF01585.25, score=44.7]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=19.3]} {Human: ENSG00000182872, RBM10, RNA binding motif protein 10, [RH, Score=328, Expect=1e-96]} {Mouse: ENSMUSG00000031060, Rbm10, RNA binding motif protein 10, [RH, Score=330, Expect=7e-98]} {Dmel: FBgn0031319, CG4896, [RH, Score=296, Expect=7e-86]} {Celegans: WBGene00020346, rbm-5, RNA Binding Motif protein homolog, [RH, Score=115, Expect=6e-26]} {Smed: dd_Smed_v6_2392_0_4, dd_Smed_v6_2392_0_4, [RH, Score=208, Expect=8e-56]} {RNA1509_10003} {RNA1310_1240.1} {RNA815_5113}
51. MligTC455_29316 541 11.27 Mlig455_044397

Neo: -

Age: Up-Down-Down

BTBD7 0.966 - - 0.966 - - - Mlig455_044397 {REF} {Length: 7648} {TRANSSPLICED} {Pfam: BTB/POZ domain [PF00651.33, score=77.1]} {Human: ENSG00000011114, BTBD7, BTB domain containing 7, [RH, Score=286, Expect=1e-82]; ENSG00000277222, BTBD7, BTB domain containing 7, [RH, Score=286, Expect=1e-82]} {Mouse: ENSMUSG00000041702, Btbd7, BTB (POZ) domain containing 7, [RH, Score=282, Expect=1e-81]} {Dmel: FBgn0030701, CG16952, [RH, Score=281, Expect=7e-82]} {Celegans: WBGene00016540, C39F7.5, [RH, Score=107, Expect=5e-24]} {Smed: dd_Smed_v6_13922_0_1, dd_Smed_v6_13922_0_1, [RH, Score=176, Expect=1e-46]} {RNA1509_19729, RNA1509_30356, RNA1509_36742, RNA1509_52027, RNA1509_54988, RNA1509_55000} {RNA1310_14407.1, RNA1509_19729, RNA1509_30356, RNA1509_36742, RNA1509_52027, RNA1509_54988, RNA1509_55000} {RNA1509_19729, RNA1509_30356, RNA1509_36742, RNA1509_52027, RNA1509_54988, RNA1509_55000, RNA815_24813}
52. MligTC455_31551 284 5.92 Mlig455_057535

Neo: -

Age: Up-Down-Down

RBM10 0.965 - - 0.965 - - - Mlig455_057535 {REF} {Length: 4657} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=50.7]; OCRE domain [PF17780.3, score=47.3]; G-patch domain [PF01585.25, score=44.7]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=19.3]} {Human: ENSG00000182872, RBM10, RNA binding motif protein 10, [RH, Score=327, Expect=4e-96]} {Mouse: ENSMUSG00000031060, Rbm10, RNA binding motif protein 10, [RH, Score=333, Expect=2e-99]} {Dmel: FBgn0031319, CG4896, [RH, Score=294, Expect=5e-85]} {Celegans: WBGene00020346, rbm-5, RNA Binding Motif protein homolog, [RH, Score=114, Expect=2e-25]} {Smed: dd_Smed_v6_2392_0_4, dd_Smed_v6_2392_0_4, [RH, Score=207, Expect=9e-56]} {RNA1509_10003} {RNA1310_1240.1} {RNA815_5113}
53. MligTC455_10921 431 8.98 Mlig455_021841, Mlig455_021917

Neo: -

Age: Up-Down-Down

GRM5 0.964 - - 0.964 - - -

Mlig455_021841 {REF} {Length: 9007} {Pfam: Receptor family ligand binding region [PF01094.30, score=472.4]} {Human: ENSG00000168959, GRM5, glutamate metabotropic receptor 5, [Score=202, Expect=2e-51]; ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=201, Expect=8e-52]} {Mouse: ENSMUSG00000049583, Grm5, glutamate receptor, metabotropic 5, [Score=201, Expect=3e-51]; ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=197, Expect=7e-51]} {Dmel: FBgn0050361, mtt, mangetout, [Score=140, Expect=8e-33]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [Score=128, Expect=2e-29]} {Smed: dd_Smed_v6_32826_0_1, dd_Smed_v6_32826_0_1, [Score=172, Expect=3e-44]} {RNA1509_2414} {RNA1310_178.1} {RNA815_189}

Mlig455_021917 {REF} {Length: 9090} {Pfam: Receptor family ligand binding region [PF01094.30, score=470.8]; 7 transmembrane sweet-taste receptor of 3 GCPR [PF00003.24, score=81.0]} {Human: ENSG00000168959, GRM5, glutamate metabotropic receptor 5, [Score=204, Expect=6e-52]; ENSG00000198822, GRM3, glutamate metabotropic receptor 3, [Score=201, Expect=7e-52]} {Mouse: ENSMUSG00000049583, Grm5, glutamate receptor, metabotropic 5, [Score=201, Expect=2e-51]; ENSMUSG00000003974, Grm3, glutamate receptor, metabotropic 3, [Score=198, Expect=5e-51]} {Dmel: FBgn0050361, mtt, mangetout, [Score=167, Expect=8e-41]} {Celegans: WBGene00003232, mgl-1, Probable metabotropic glutamate receptor mgl-1, [Score=130, Expect=9e-30]} {Smed: dd_Smed_v6_32826_0_1, dd_Smed_v6_32826_0_1, [Score=172, Expect=3e-44]} {RNA1509_2414} {RNA1310_178.1, RNA1509_2414} {RNA1509_2414, RNA815_189}
54. MligTC455_33922 235 4.89 Mlig455_032137

Neo: -

Age: logFC(26M/2M)=-0.421

SLC7A8 0.963 - - 0.963 - - - Mlig455_032137 {REF} {Length: 3423} {Pfam: Amino acid permease [PF13520.8, score=218.6]; Amino acid permease [PF00324.23, score=127.0]} {Human: ENSG00000092068, SLC7A8, solute carrier family 7 member 8, [Score=385, Expect=4e-127]; ENSG00000151012, SLC7A11, solute carrier family 7 member 11, [Score=384, Expect=2e-127]; ENSG00000103257, SLC7A5, solute carrier family 7 member 5, [Score=383, Expect=8e-127]; ENSG00000103064, SLC7A6, solute carrier family 7 member 6, [Score=371, Expect=7e-122]} {Mouse: ENSMUSG00000027737, Slc7a11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11, [Score=416, Expect=1e-139]} {Dmel: FBgn0039487, gb, genderblind, [RH, Score=408, Expect=2e-136]} {Celegans: WBGene00000002, aat-1, Amino Acid Transporter, [Score=365, Expect=2e-120]} {Smed: dd_Smed_v6_4211_0_1, dd_Smed_v6_4211_0_1, [Score=436, Expect=2e-147]} {RNA1509_53982} {RNA1310_8199.1} {RNA815_2788}
55. MligTC455_40201 607 12.65 Mlig455_052028

Neo: -

Age: logFC(26M/2M)=-0.526

DCLK3 0.963 - - 0.963 - - - Mlig455_052028 {REF} {Length: 3990} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.8]; Fungal protein kinase [PF17667.3, score=26.5]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=19.0]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=370, Expect=2e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=8e-110]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=369, Expect=3e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=295, Expect=7e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=351, Expect=2e-105]} {RNA1509_13597} {RNA1310_2158.1} {RNA815_2598}
56. MligTC455_40202 595 12.39 Mlig455_057253

Neo: -

Age: logFC(26M/2M)=-0.440

DCLK3 0.963 - - 0.963 - - - Mlig455_057253 {REF} {Length: 4012} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=245.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.1]; Doublecortin [PF03607.19, score=80.9]; Fungal protein kinase [PF17667.3, score=25.3]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=18.9]} {Human: ENSG00000163673, DCLK3, doublecortin like kinase 3, [RH, Score=371, Expect=1e-115]; ENSG00000133083, DCLK1, doublecortin like kinase 1, [RH, Score=358, Expect=2e-113]} {Mouse: ENSMUSG00000032500, Dclk3, doublecortin-like kinase 3, [RH, Score=370, Expect=1e-113]; ENSMUSG00000027797, Dclk1, doublecortin-like kinase 1, [RH, Score=357, Expect=4e-109]} {Dmel: FBgn0261387, CG17528, [RH, Score=296, Expect=6e-87]} {Celegans: WBGene00006993, zyg-8, Serine/threonine-protein kinase zyg-8, [RH, Score=231, Expect=1e-63]} {Smed: dd_Smed_v6_12689_0_1, dd_Smed_v6_12689_0_1, [RH, Score=352, Expect=1e-105]} {RNA1509_13597, RNA1509_49808} {RNA1310_2158.1, RNA1509_13597, RNA1509_49808} {RNA1509_13597, RNA1509_49808, RNA815_2598}
57. MligTC455_45490 142 2.96 Mlig455_063525

Neo: -

Age: -

0.963 - - 0.963 - - - Mlig455_063525 {REF} {Length: 1610} {NoTransDecoderORF} {RNA1509_40743} {RNA1310_36528} {RNA815_25387.1}
58. MligTC455_13094 121 2.52 Mlig455_005442, Mlig455_005513

Neo: -

Age: Up-Up-Down

0.962 - - 0.962 - - -

Mlig455_005442 {REF} {Length: 3816} {Smed: dd_Smed_v6_15433_0_1, dd_Smed_v6_15433_0_1, [Score=141, Expect=1e-34]} {RNA1509_41201} {RNA1310_51044} {RNA815_32534}

Mlig455_005513 {REF} {Length: 685} {NoTransDecoderORF} {RNA1310_56412} {RNA815_32534}
59. MligTC455_07984 111 2.32 Mlig455_050041

Neo: -

Age: -

0.961 - - 0.961 - - - Mlig455_050041 {REF} {Length: 355} {Pfam: Essential protein Yae1, N terminal [PF09811.11, score=22.7]}
60. MligTC455_40580 489 10.18 Mlig455_035816

Neo: -

Age: Down-Up-Down

0.961 - - 0.961 - - - Mlig455_035816 {REF} {Length: 5011} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=26.3]} {Smed: dd_Smed_v6_3171_0_1, dd_Smed_v6_3171_0_1, [RH, Score=102, Expect=3e-24]} {RNA1509_14030, RNA1509_21360} {RNA1310_15645, RNA1509_14030, RNA1509_21360} {RNA1509_14030, RNA1509_21360, RNA815_4821.1}
61. MligTC455_54164 484 10.08 Mlig455_066681

Neo: -

Age: logFC(26M/2M)=0.269

ALG11 0.961 - - 0.961 - - - Mlig455_066681 {REF} {Length: 3805} {TRANSSPLICED} {Pfam: ALG11 mannosyltransferase N-terminus [PF15924.7, score=213.1]; Glycosyl transferases group 1 [PF00534.22, score=88.2]; Glycosyl transferases group 1 [PF13692.8, score=47.4]} {Human: ENSG00000253710, ALG11, ALG11, alpha-1,2-mannosyltransferase, [RH, Score=348, Expect=4e-114]} {Mouse: ENSMUSG00000063362, Alg11, asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase), [RH, Score=336, Expect=6e-110]} {Dmel: FBgn0037108, CG11306, [Score=326, Expect=3e-106]} {Celegans: WBGene00015162, algn-11, GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, [Score=260, Expect=4e-81]} {Smed: dd_Smed_v6_6817_0_1, dd_Smed_v6_6817_0_1, [RH, Score=295, Expect=1e-94]} {RNA1509_50483, RNA1509_7550} {RNA1310_18644.1, RNA1509_50483} {RNA1509_50483, RNA815_14948}
62. MligTC455_27762 36 0.75 Mlig455_057101

Neo: -

Age: logFC(26M/2M)=-0.242

TAF5L 0.96 - - 0.960 - - - Mlig455_057101 {REF} {Length: 3324} {Pfam: WD domain, G-beta repeat [PF00400.34, score=80.4]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=36.5]} {Human: ENSG00000135801, TAF5L, TATA-box binding protein associated factor 5 like, [Score=61.2, Expect=5e-09]; ENSG00000148835, TAF5, TATA-box binding protein associated factor 5, [Score=60.8, Expect=8e-09]} {Mouse: ENSMUSG00000038697, Taf5l, TATA-box binding protein associated factor 5 like, [Score=62.4, Expect=1e-09]; ENSMUSG00000025049, Taf5, TATA-box binding protein associated factor 5, [Score=60.5, Expect=6e-09]} {Smed: dd_Smed_v6_16089_0_1, dd_Smed_v6_16089_0_1, [RH, Score=497, Expect=2e-165]} {RNA1509_36023, RNA1509_8093} {RNA1310_7410, RNA1509_36023, RNA1509_8093} {RNA1509_36023, RNA1509_8093, RNA815_1988.1}
63. MligTC455_28518 184 3.84 Mlig455_068682

Neo: -

Age: Down-Down-Up

ANKRD50 0.96 - - 0.960 - - - Mlig455_068682 {REF} {Length: 5526} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=137.6]; Ankyrin repeat [PF00023.32, score=109.8]; Ankyrin repeats (many copies) [PF13857.8, score=106.4]; Ankyrin repeat [PF13606.8, score=102.1]; Mab-21 protein [PF03281.16, score=30.7]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=158, Expect=1e-38]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=157, Expect=2e-38]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=135, Expect=8e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=134, Expect=1e-31]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=140, Expect=6e-34]} {RNA1509_18101} {RNA1310_3035.1, RNA1509_18101} {RNA1509_18101, RNA815_4096}
64. MligTC455_36117 406 8.45 Mlig455_032713

Neo: Neoblast, stringent

Age: -

POLA1 0.96 - - 0.960 - - - Mlig455_032713 {REF} {Length: 5929} {TRANSSPLICED} {Pfam: DNA polymerase family B [PF00136.23, score=355.1]; DNA Polymerase alpha zinc finger [PF08996.12, score=85.3]; DNA polymerase family B, exonuclease domain [PF03104.21, score=71.1]} {Human: ENSG00000101868, POLA1, DNA polymerase alpha 1, catalytic subunit, [RH, Score=760, Expect=0.0]} {Mouse: ENSMUSG00000006678, Pola1, polymerase (DNA directed), alpha 1, [RH, Score=745, Expect=0.0]} {Dmel: FBgn0259113, DNApol-alpha180, DNA polymerase alpha 180kD, [RH, Score=655, Expect=0.0]} {Celegans: WBGene00012936, pola-1, DNA polymerase, [RH, Score=575, Expect=7e-179]} {Smed: dd_Smed_v6_9168_0_1, dd_Smed_v6_9168_0_1, [RH, Score=618, Expect=0.0]} {RNA1509_10689, RNA1509_5465} {RNA1310_1287, RNA1509_10689, RNA1509_5465} {RNA1509_10689, RNA1509_5465, RNA815_2020}
65. MligTC455_08750 350 7.3 Mlig455_065136

Neo: -

Age: Down-Down-Up

LRIG2 0.959 - - 0.959 - - - Mlig455_065136 {REF} {Length: 4429} {Pfam: Leucine rich repeat [PF13855.8, score=110.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=56.5]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=45.3]; Leucine Rich Repeat [PF00560.35, score=35.2]; Leucine-rich repeat [PF14580.8, score=25.5]; Leucine Rich repeat [PF13516.8, score=23.2]} {Human: ENSG00000198799, LRIG2, leucine rich repeats and immunoglobulin like domains 2, [Score=92.8, Expect=6e-19]; ENSG00000099769, IGFALS, insulin like growth factor binding protein acid labile subunit, [Score=88.6, Expect=8e-18]} {Mouse: ENSMUSG00000032913, Lrig2, leucine-rich repeats and immunoglobulin-like domains 2, [Score=90.5, Expect=2e-18]} {Dmel: FBgn0037552, CG7800, [RH, Score=78.2, Expect=7e-15]} {Celegans: WBGene00011971, lron-9, ELRR (Extracellular Leucine-Rich Repeat) ONly, [Score=71.2, Expect=1e-12]} {Smed: dd_Smed_v6_2769_0_1, dd_Smed_v6_2769_0_1, [Score=70.5, Expect=1e-12]} {RNA1509_49189} {RNA1310_8830} {RNA815_10512}
66. MligTC455_20474 64 1.33 Mlig455_016388

Neo: -

Age: -

0.959 - - 0.959 - - - Mlig455_016388 {REF} {Length: 1044} {RNA1310_43059}
67. MligTC455_21945 377 7.85 Mlig455_008445

Neo: -

Age: -

FAT1 0.959 - - 0.959 - - - Mlig455_008445 {REF} {Length: 11205} {Pfam: Cadherin domain [PF00028.19, score=320.9]; Cadherin cytoplasmic region [PF01049.19, score=83.8]; Laminin G domain [PF02210.26, score=80.1]; Laminin G domain [PF00054.25, score=55.7]; Cadherin-like [PF16184.7, score=33.3]; EGF-like domain [PF00008.29, score=28.8]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=314, Expect=8e-85]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=295, Expect=3e-79]; ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=285, Expect=3e-76]} {Dmel: FBgn0015609, CadN, Cadherin-N, [Score=659, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [Score=399, Expect=2e-111]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=133, Expect=1e-30]} {RNA1509_42554, RNA1509_5143} {RNA1310_146.1, RNA1509_42554} {RNA1509_42554, RNA815_203}
68. MligTC455_24774 198 4.11 Mlig455_033948

Neo: -

Age: -

LRIG3 0.959 - - 0.959 - - - Mlig455_033948 {REF} {Length: 5691} {Pfam: Leucine rich repeat [PF13855.8, score=88.8]; Leucine Rich repeats (2 copies) [PF12799.9, score=64.5]; Leucine-rich repeat [PF14580.8, score=23.0]} {Human: ENSG00000139263, LRIG3, leucine rich repeats and immunoglobulin like domains 3, [Score=59.3, Expect=5e-08]} {Mouse: ENSMUSG00000020105, Lrig3, leucine-rich repeats and immunoglobulin-like domains 3, [Score=64.7, Expect=6e-10]} {Dmel: FBgn0029114, Tollo, [Score=59.3, Expect=2e-08]} {Celegans: WBGene00006593, tol-1, TOLl (Drosophila) family, [Score=52.4, Expect=2e-06]} {Smed: dd_Smed_v6_11527_0_1, dd_Smed_v6_11527_0_1, [Score=54.7, Expect=2e-07]} {RNA1509_25651} {RNA1310_2369, RNA1509_25651} {RNA1509_25651, RNA815_18102}
69. MligTC455_33199 144 3 Mlig455_068562

Neo: -

Age: -

CAMKK2 0.958 - - 0.958 - - - Mlig455_068562 {REF} {Length: 3078} {Pfam: Protein kinase domain [PF00069.27, score=209.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=121.7]; Kinase-like [PF14531.8, score=30.4]; Fungal protein kinase [PF17667.3, score=19.0]} {Human: ENSG00000110931, CAMKK2, calcium/calmodulin dependent protein kinase kinase 2, [RH, Score=417, Expect=4e-138]} {Mouse: ENSMUSG00000029471, Camkk2, calcium/calmodulin-dependent protein kinase kinase 2, beta, [RH, Score=409, Expect=4e-135]; ENSMUSG00000020785, Camkk1, calcium/calmodulin-dependent protein kinase kinase 1, alpha, [RH, Score=394, Expect=1e-129]} {Dmel: FBgn0040056, CG17698, [RH, Score=402, Expect=1e-130]} {Celegans: WBGene00000518, ckk-1, Calcium/calmodulin-dependent protein kinase kinase, [RH, Score=414, Expect=3e-137]} {Smed: dd_Smed_v6_18437_0_1, dd_Smed_v6_18437_0_1, [RH, Score=367, Expect=3e-118]} {RNA1509_51718} {RNA1310_7593.1} {RNA815_7566}
70. MligTC455_36362 266 5.55 Mlig455_029693, Mlig455_034838

Neo: -

Age: -

TLCD1 0.958 - - 0.958 - - -

Mlig455_029693 {REF} {Length: 2356} {Pfam: TLC domain [PF03798.18, score=71.5]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=93.2, Expect=6e-22]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=94.4, Expect=1e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=100, Expect=2e-24]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=237, Expect=1e-77]} {RNA1509_18403} {RNA1310_26765} {RNA815_14967}

Mlig455_034838 {REF} {Length: 4633} {Pfam: TLC domain [PF03798.18, score=71.6]} {Human: ENSG00000160606, TLCD1, TLC domain containing 1, [RH, Score=92.4, Expect=1e-21]} {Mouse: ENSMUSG00000019437, Tlcd1, TLC domain containing 1, [RH, Score=93.6, Expect=3e-22]} {Celegans: WBGene00013407, Y63D3A.8, [RH, Score=101, Expect=7e-25]} {Smed: dd_Smed_v6_6951_0_2, dd_Smed_v6_6951_0_2, [Score=236, Expect=4e-77]} {RNA1509_18403} {RNA1310_7362.1} {RNA815_6705.1}
71. MligTC455_42680 1410 29.37 Mlig455_057043

Neo: -

Age: -

0.958 - - - - - 0.958 Mlig455_057043 {REF} {Length: 1934} {NoTransDecoderORF} {RNA1509_20619} {RNA1310_24331.1} {RNA815_10810.1}
72. MligTC455_52274 404 8.42 Mlig455_060338

Neo: -

Age: logFC(26M/2M)=0.241

MLLT10 0.958 - - 0.958 - - - Mlig455_060338 {REF} {Length: 4097} {TRANSSPLICED} {Pfam: PHD-zinc-finger like domain [PF13832.8, score=69.8]; PHD-finger [PF13831.8, score=37.3]; PHD-like zinc-binding domain [PF13771.8, score=32.0]; PHD-finger [PF00628.31, score=31.2]} {Human: ENSG00000078403, MLLT10, MLLT10, histone lysine methyltransferase DOT1L cofactor, [Score=147, Expect=9e-36]; ENSG00000275851, MLLT6, MLLT6, PHD finger containing, [Score=142, Expect=6e-34]; ENSG00000275023, MLLT6, MLLT6, PHD finger containing, [Score=142, Expect=6e-34]} {Mouse: ENSMUSG00000026743, Mllt10, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10, [Score=148, Expect=4e-36]; ENSMUSG00000038437, Mllt6, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6, [Score=141, Expect=5e-34]} {Dmel: FBgn0261238, Alh, Alhambra, [Score=149, Expect=2e-36]} {Celegans: WBGene00006975, zfp-1, isoform a, [Score=128, Expect=4e-30]} {Smed: dd_Smed_v6_7497_0_1, dd_Smed_v6_7497_0_1, [Score=134, Expect=2e-32]} {RNA1509_20411, RNA1509_52660} {RNA1310_17114, RNA1509_20411, RNA1509_52660} {RNA1509_20411, RNA1509_52660, RNA815_34430.1}
73. MligTC455_12235 31 0.65 Mlig455_009699

Neo: -

Age: -

0.957 - - 0.957 - - - Mlig455_009699 {REF} {Length: 2954} {RNA1509_46647} {RNA1310_94016} {RNA815_58198}
74. MligTC455_18472 662 13.79 Mlig455_065928

Neo: -

Age: -

0.957 - - - - - 0.957 Mlig455_065928 {REF} {Length: 2444} {RNA1509_24487} {RNA1310_16089.1} {RNA815_13960}
75. MligTC455_41605 469 9.76 Mlig455_044610

Neo: -

Age: -

PXMP2 0.957 - - 0.957 - - - Mlig455_044610 {REF} {Length: 3196} {TRANSSPLICED} {Pfam: Mpv17 / PMP22 family [PF04117.14, score=54.5]} {Human: ENSG00000176894, PXMP2, peroxisomal membrane protein 2, [Score=47.4, Expect=3e-06]} {Dmel: FBgn0039930, CG11077, [RH, Score=76.3, Expect=2e-17]} {Celegans: WBGene00011826, T18D3.9, Mpv17-like protein, [Score=66.6, Expect=1e-13]} {Smed: dd_Smed_v6_11900_0_1, dd_Smed_v6_11900_0_1, [Score=54.7, Expect=2e-09]} {RNA1509_24979} {RNA1310_38509, RNA1509_24979} {RNA1509_24979, RNA815_22844}
76. MligTC455_15051 112 2.33 Mlig455_028585, Mlig455_056915

Neo: -

Age: -

0.956 - - 0.956 - - -

Mlig455_028585 {REF} {Length: 982} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=86.7, Expect=1e-19]} {RNA1509_32017} {RNA1310_2395.2} {RNA815_496.1}

Mlig455_056915 {REF} {Length: 1277} {Smed: dd_Smed_v6_3795_0_2, dd_Smed_v6_3795_0_2, [RH, Score=86.7, Expect=1e-19]} {RNA1509_32017} {RNA1310_2395.2} {RNA815_496.1}
77. MligTC455_15536 41 0.86 Mlig455_030649

Neo: -

Age: -

0.956 - - 0.956 - - - Mlig455_030649 {REF} {Length: 1146} {RNA1310_33769.1} {RNA815_16068}
78. MligTC455_18473 658 13.71 Mlig455_065950

Neo: -

Age: -

0.956 - - - - - 0.956 Mlig455_065950 {REF} {Length: 1966} {TRANSSPLICED} {RNA1509_24487, RNA1509_46170} {RNA1310_16089.1, RNA1509_24487, RNA1509_46170} {RNA1509_24487, RNA1509_46170, RNA815_13960}
79. MligTC455_21470 491 10.23 Mlig455_028994

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

KCNMA1 0.956 - - 0.956 - - - Mlig455_028994 {REF} {Length: 4059} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=82.1]; Ion channel [PF07885.18, score=48.7]; Ion transport protein [PF00520.33, score=31.6]; TrkA-N domain [PF02254.20, score=27.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=484, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=482, Expect=5e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=479, Expect=1e-150]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=461, Expect=5e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=490, Expect=3e-155]} {RNA1509_10617} {RNA1310_2480.1} {RNA815_984.1}
80. MligTC455_23843 66 1.38 Mlig455_000716

Neo: -

Age: -

0.956 - - 0.956 - - - Mlig455_000716 {REF} {Length: 3789} {NoTransDecoderORF} {RNA1509_51543} {RNA1310_39627} {RNA815_33289}
81. MligTC455_33345 73 1.53 Mlig455_022775

Neo: -

Age: Up-Down-Down

ITPR2 0.956 - - 0.956 - - - Mlig455_022775 {REF} {Length: 10477} {Pfam: RIH domain [PF01365.23, score=93.1]; RyR and IP3R Homology associated [PF08454.13, score=68.6]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=68.1]; MIR domain [PF02815.21, score=57.0]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=204, Expect=1e-51]} {Mouse: ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=206, Expect=3e-52]; ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=199, Expect=3e-50]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=157, Expect=1e-37]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=146, Expect=2e-34]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [RH, Score=3019, Expect=0.0]} {RNA1509_31887} {RNA1310_193.1} {RNA815_9899}
82. MligTC455_41197 316 6.58 Mlig455_017826

Neo: -

Age: -

CAMK4 0.956 - - 0.956 - - - Mlig455_017826 {REF} {Length: 1398} {Pfam: Protein kinase domain [PF00069.27, score=243.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=104.3]; ABC1 atypical kinase-like domain [PF03109.18, score=19.6]} {Human: ENSG00000152495, CAMK4, calcium/calmodulin dependent protein kinase IV, [Score=358, Expect=6e-121]} {Mouse: ENSMUSG00000038128, Camk4, calcium/calmodulin-dependent protein kinase IV, [Score=363, Expect=5e-123]} {Dmel: FBgn0016126, CaMKI, Calcium/calmodulin-dependent protein kinase I, [Score=256, Expect=2e-82]} {Celegans: WBGene00000553, cmk-1, Calcium/calmodulin-dependent protein kinase type 1, [Score=261, Expect=3e-85]} {Smed: dd_Smed_v6_10731_0_1, dd_Smed_v6_10731_0_1, [Score=363, Expect=5e-125]} {RNA1509_46951} {RNA1310_29212.1, RNA1509_46951} {RNA1509_46951, RNA815_16533}
83. MligTC455_43120 247 5.15 Mlig455_025263

Neo: -

Age: Up-Down-Down

0.956 - - 0.956 - - - Mlig455_025263 {REF} {Length: 4290} {RNA1509_20151} {RNA1310_8688.1} {RNA815_9458.1}
84. MligTC455_19767 316 6.58 Mlig455_066462

Neo: -

Age: -

MFN2 0.955 - - 0.955 - - - Mlig455_066462 {REF} {Length: 3855} {TRANSSPLICED} {Pfam: fzo-like conserved region [PF04799.15, score=166.1]; Dynamin family [PF00350.25, score=91.3]; 50S ribosome-binding GTPase [PF01926.25, score=33.2]} {Human: ENSG00000116688, MFN2, mitofusin 2, [RH, Score=569, Expect=0.0]; ENSG00000171109, MFN1, mitofusin 1, [RH, Score=543, Expect=0.0]} {Mouse: ENSMUSG00000029020, Mfn2, mitofusin 2, [RH, Score=576, Expect=0.0]; ENSMUSG00000027668, Mfn1, mitofusin 1, [RH, Score=558, Expect=0.0]} {Dmel: FBgn0029870, Marf, Mitochondrial assembly regulatory factor, [RH, Score=581, Expect=0.0]} {Celegans: WBGene00001509, fzo-1, Transmembrane GTPase fzo-1, [RH, Score=405, Expect=9e-130]} {Smed: dd_Smed_v6_2168_0_1, dd_Smed_v6_2168_0_1, [RH, Score=576, Expect=0.0]} {RNA1509_18473, RNA1509_33024, RNA1509_6996} {RNA1310_1685.1, RNA1509_18473, RNA1509_33024, RNA1509_6996} {RNA1509_18473, RNA1509_33024, RNA1509_6996, RNA815_384.2}
85. MligTC455_41434 736 15.32 Mlig455_034800

Neo: Irradiation

Age: -

0.955 - - - - - 0.955 Mlig455_034800 {REF} {Length: 2333} {TRANSSPLICED} {RNA1509_11589, RNA1509_43191, RNA1509_54049} {RNA1310_26849.1, RNA1509_11589, RNA1509_43191, RNA1509_54049} {RNA1509_11589, RNA1509_43191, RNA1509_54049, RNA815_11952}
86. MligTC455_49526 450 9.38 Mlig455_050949

Neo: -

Age: logFC(26M/2M)=-0.615

CALM2 0.955 - - 0.955 - - - Mlig455_050949 {REF} {Length: 3680} {Pfam: EF-hand domain pair [PF13499.8, score=87.8]; EF hand [PF00036.34, score=79.8]; EF-hand domain [PF13405.8, score=67.4]; EF hand [PF13202.8, score=65.4]; EF-hand domain pair [PF13833.8, score=60.3]; EF-hand domain [PF08976.13, score=22.2]; EF-hand domain [PF14658.8, score=21.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.9]; Secreted protein acidic and rich in cysteine Ca binding region [PF10591.11, score=18.9]} {Human: ENSG00000143933, CALM2, calmodulin 2, [Score=100, Expect=5e-24]; ENSG00000198668, CALM1, calmodulin 1, [Score=100, Expect=5e-24]; ENSG00000160014, CALM3, calmodulin 3, [Score=100, Expect=5e-24]; ENSG00000178363, CALML3, calmodulin like 3, [Score=99.4, Expect=8e-24]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=103, Expect=9e-25]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=102, Expect=4e-25]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=100, Expect=3e-24]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=100, Expect=3e-24]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=99.0, Expect=6e-24]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=102, Expect=4e-25]} {Smed: dd_Smed_v6_414_0_1, dd_Smed_v6_414_0_1, [Score=100, Expect=1e-24]} {RNA1509_48556} {RNA1310_10152.1} {RNA815_3673.1}
87. MligTC455_07619 86 1.79 Mlig455_046331

Neo: -

Age: -

0.954 - - 0.954 - - - Mlig455_046331 {REF} {Length: 231} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_46130} {RNA1310_1262.2} {RNA815_4161}
88. MligTC455_19441 305 6.35 Mlig455_001985

Neo: -

Age: logFC(26M/2M)=-0.555

Region-enriched R2: 2.029/0.00606

0.954 - - 0.954 - - - Mlig455_001985 {REF} {Length: 2497} {RNA1509_40470} {RNA1310_22476.3, RNA1509_40470} {RNA1509_40470, RNA815_16128}
89. MligTC455_32894 528 11 Mlig455_006799, Mlig455_054736

Neo: -

Age: logFC(26M/2M)=-0.373

ANK3 0.954 - - 0.954 - - -

Mlig455_006799 {REF} {Length: 2211} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=199.6]; Ankyrin repeats (many copies) [PF13637.8, score=140.6]; Ankyrin repeats (many copies) [PF13857.8, score=101.3]; Ankyrin repeat [PF13606.8, score=91.0]; Ankyrin repeat [PF00023.32, score=74.7]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=116, Expect=2e-27]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=114, Expect=2e-26]} {Mouse: ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=114, Expect=1e-26]; ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=113, Expect=1e-26]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=102, Expect=7e-23]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=101, Expect=7e-23]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [RH, Score=224, Expect=8e-69]} {RNA1509_50010} {RNA1310_23872} {RNA815_11047.1}

Mlig455_054736 {REF} {Length: 2242} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=187.9]; Ankyrin repeats (many copies) [PF13637.8, score=141.3]; Ankyrin repeats (many copies) [PF13857.8, score=101.2]; Ankyrin repeat [PF13606.8, score=89.9]; Ankyrin repeat [PF00023.32, score=74.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=116, Expect=2e-27]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=115, Expect=3e-27]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=115, Expect=3e-27]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=114, Expect=1e-26]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=102, Expect=7e-23]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=101, Expect=7e-23]} {Smed: dd_Smed_v6_13251_0_1, dd_Smed_v6_13251_0_1, [RH, Score=224, Expect=7e-69]} {RNA1509_45433, RNA1509_50010} {RNA1310_23872, RNA1509_45433, RNA1509_50010} {RNA1509_45433, RNA1509_50010, RNA815_11047.1}
90. MligTC455_53603 211 4.39 Mlig455_070647

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.345

HOOK3 0.954 - - 0.954 - - - Mlig455_070647 {REF} {Length: 2917} {Pfam: HOOK protein coiled-coil region [PF05622.14, score=280.3]; HOOK domain [PF19047.2, score=193.1]} {Human: ENSG00000168172, HOOK3, hook microtubule tethering protein 3, [RH, Score=384, Expect=1e-123]} {Mouse: ENSMUSG00000037234, Hook3, hook microtubule tethering protein 3, [RH, Score=377, Expect=4e-121]} {Dmel: FBgn0001202, hook, [RH, Score=257, Expect=4e-76]} {Smed: dd_Smed_v6_8306_0_1, dd_Smed_v6_8306_0_1, [RH, Score=243, Expect=2e-70]} {RNA1509_4937} {RNA1310_7268} {RNA815_3630.1}
91. MligTC455_53608 2624 54.66 Mlig455_066346

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=2.900

SPAG6 0.954 - - 0.954 - - - Mlig455_066346 {REF} {Length: 1967} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=130.5]; HEAT repeats [PF13646.8, score=55.3]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=52.1]; HEAT repeat [PF02985.24, score=50.8]; HEAT-like repeat [PF13513.8, score=35.3]; Adaptin N terminal region [PF01602.22, score=31.7]; C-terminal domain of two-partite extracellular sensor domain [PF17150.6, score=31.5]; DNA alkylation repair enzyme [PF08713.13, score=30.7]; Proteasome non-ATPase 26S subunit [PF10508.11, score=24.4]; Rapamycin-insensitive companion of mTOR, N-term [PF14664.8, score=19.6]} {Human: ENSG00000077327, SPAG6, sperm associated antigen 6, [RH, Score=863, Expect=0.0]} {Mouse: ENSMUSG00000022783, Spag6l, sperm associated antigen 6-like, [RH, Score=881, Expect=0.0]} {Dmel: FBgn0024889, Kap-alpha1, karyopherin alpha1, [Score=65.5, Expect=5e-11]} {Celegans: WBGene00002074, ima-3, Importin subunit alpha-3, [Score=70.9, Expect=8e-13]} {Smed: dd_Smed_v6_3991_0_1, dd_Smed_v6_3991_0_1, [RH, Score=894, Expect=0.0]} {RNA1509_1649} {RNA1310_12357} {RNA815_5582.1}
92. MligTC455_24506 573 11.95 Mlig455_003680

Neo: -

Age: -

NR1I2 0.953 - - 0.953 - - - Mlig455_003680 {REF} {Length: 3889} {TRANSSPLICED} {Pfam: Zinc finger, C4 type (two domains) [PF00105.20, score=76.0]} {Human: ENSG00000144852, NR1I2, nuclear receptor subfamily 1 group I member 2, [Score=84.0, Expect=1e-16]} {Mouse: ENSMUSG00000022809, Nr1i2, nuclear receptor subfamily 1, group I, member 2, [Score=80.9, Expect=8e-16]; ENSMUSG00000002393, Nr2f6, nuclear receptor subfamily 2, group F, member 6, [Score=79.7, Expect=1e-15]; ENSMUSG00000024955, Esrra, estrogen related receptor, alpha, [Score=77.4, Expect=1e-14]; ENSMUSG00000022479, Vdr, vitamin D (1,25-dihydroxyvitamin D3) receptor, [Score=77.4, Expect=1e-14]} {Dmel: FBgn0015240, Hr96, Hormone receptor-like in 96, [Score=75.9, Expect=5e-14]} {Celegans: WBGene00000908, daf-12, Nuclear hormone receptor family member daf-12, [Score=94.4, Expect=5e-20]} {Smed: dd_Smed_v6_5200_0_1, dd_Smed_v6_5200_0_1, [Score=106, Expect=2e-24]} {RNA1509_19887, RNA1509_4070} {RNA1310_895.1, RNA1509_19887} {RNA1509_19887, RNA815_1055}
93. MligTC455_30234 668 13.92 Mlig455_013688, Mlig455_020164, Mlig455_028077, Mlig455_036489, Mlig455_038238, Mlig455_049777, Mlig455_054410, Mlig455_055118, Mlig455_061417, Mlig455_068974, Mlig455_070511

Neo: -

Age: Up-Down-Down

PIF1 0.953 - - 0.953 - - -

Mlig455_013688 {REF} {Length: 3931} {Pfam: PIF1-like helicase [PF05970.16, score=335.0]; AAA domain [PF13604.8, score=47.7]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=1e-149]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=5e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_020164 {REF} {Length: 6683} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; AAA domain [PF13604.8, score=47.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.2]; AAA domain [PF13245.8, score=19.4]; Helicase [PF02689.16, score=16.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=3e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=5e-150]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_6950, RNA1509_5036} {RNA1509_5036, RNA815_356.1}

Mlig455_028077 {REF} {Length: 5927} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=333.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.6]; AAA domain [PF13604.8, score=45.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.1]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=121, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=3e-28]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=737, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_036489 {REF} {Length: 6279} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=335.1]; AAA domain [PF13604.8, score=47.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=6e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=509, Expect=7e-161]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_038238 {REF} {Length: 7170} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.3]; AAA domain [PF13604.8, score=44.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.2]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=8e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=8e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=121, Expect=1e-27]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=736, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_049777 {REF} {Length: 6866} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=175.0]; AAA domain [PF13604.8, score=43.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=123, Expect=8e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=117, Expect=2e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=120, Expect=2e-27]} {Celegans: WBGene00019136, F59H6.5, [Score=760, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=1e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_054410 {REF} {Length: 3239} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=52.6]} {Celegans: WBGene00022692, ZK250.9, [Score=162, Expect=8e-44]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=45.1, Expect=8e-06]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_055118 {REF} {Length: 6779} {Pfam: PIF1-like helicase [PF05970.16, score=330.1]; Helitron helicase-like domain at N-terminus [PF14214.8, score=169.5]; AAA domain [PF13604.8, score=47.3]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=5e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=118, Expect=7e-27]} {Celegans: WBGene00018020, F33H12.6, [Score=733, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=113, Expect=2e-25]} {RNA1509_5036} {RNA1310_6950} {RNA815_356.1}

Mlig455_061417 {REF} {Length: 5410} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=169.0]; PIF1-like helicase [PF05970.16, score=56.8]; AAA domain [PF13604.8, score=20.6]} {Celegans: WBGene00019136, F59H6.5, [Score=540, Expect=1e-169]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=70.5, Expect=4e-14]} {RNA1509_5036} {RNA1310_11485} {RNA815_356.1}

Mlig455_068974 {REF} {Length: 6598} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.8]; AAA domain [PF13604.8, score=46.0]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=127, Expect=5e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=3e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=2e-28]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_070511 {REF} {Length: 6556} {Pfam: PIF1-like helicase [PF05970.16, score=335.6]; AAA domain [PF13604.8, score=48.1]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.5]; AAA domain [PF13245.8, score=19.7]; Helicase [PF02689.16, score=16.9]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=4e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=119, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=391, Expect=6e-119]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=3e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
94. MligTC455_30984 72 1.51 Mlig455_045664

Neo: -

Age: logFC(26M/2M)=-0.318

Region-enriched R4: 4.894/0.00976

VDAC2 0.953 - - 0.953 - - - Mlig455_045664 {REF} {Length: 3932} {TRANSSPLICED} {Pfam: Eukaryotic porin [PF01459.24, score=212.5]; TATA element modulatory factor 1 TATA binding [PF12325.10, score=19.5]} {Human: ENSG00000165637, VDAC2, voltage dependent anion channel 2, [RH, Score=275, Expect=4e-85]; ENSG00000213585, VDAC1, voltage dependent anion channel 1, [RH, Score=265, Expect=2e-81]} {Mouse: ENSMUSG00000021771, Vdac2, voltage-dependent anion channel 2, [RH, Score=277, Expect=7e-86]; ENSMUSG00000020402, Vdac1, voltage-dependent anion channel 1, [RH, Score=268, Expect=2e-82]} {Dmel: FBgn0004363, porin, [RH, Score=255, Expect=5e-78]} {Celegans: WBGene00019900, vdac-1, Probable voltage-dependent anion-selective channel, [Score=159, Expect=1e-43]} {Smed: dd_Smed_v6_2119_0_1, dd_Smed_v6_2119_0_1, [RH, Score=206, Expect=5e-60]} {RNA1509_26410, RNA1509_9326} {RNA1310_13038, RNA1509_26410, RNA1509_9326} {RNA1509_26410, RNA1509_9326, RNA815_4253}
95. MligTC455_53501 350 7.29 Mlig455_037470

Neo: -

Age: -

IFT22 0.953 - - 0.953 - - - Mlig455_037470 {REF} {Length: 910} {Pfam: Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=42.7]; Ras family [PF00071.24, score=36.8]; ADP-ribosylation factor family [PF00025.23, score=35.3]; Signal recognition particle receptor beta subunit [PF09439.12, score=20.4]} {Human: ENSG00000128581, IFT22, intraflagellar transport 22, [RH, Score=148, Expect=5e-45]} {Mouse: ENSMUSG00000007987, Ift22, intraflagellar transport 22, [RH, Score=139, Expect=8e-42]} {Celegans: WBGene00012132, ifta-2, Intraflagellar transport associated protein 2, [RH, Score=95.9, Expect=2e-24]} {Smed: dd_Smed_v6_11176_0_1, dd_Smed_v6_11176_0_1, [RH, Score=213, Expect=4e-71]} {RNA1509_53245} {RNA1310_41419} {RNA815_20100}
96. MligTC455_42231 324 6.74 Mlig455_012002

Neo: -

Age: logFC(26M/2M)=0.345

0.952 - - 0.952 - - - Mlig455_012002 {REF} {Length: 1795} {TRANSSPLICED} {Pfam: Protein of unknown function (DUF1294) [PF06961.15, score=65.9]} {RNA1509_25091} {RNA1310_14788, RNA1509_25091} {RNA1509_25091, RNA815_13934}
97. MligTC455_49957 119 2.47 Mlig455_005610, Mlig455_014448

Neo: -

Age: -

0.952 - - 0.952 - - -

Mlig455_005610 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=66.2, Expect=4e-13]} {RNA1310_45206} {RNA815_28788}

Mlig455_014448 {REF} {Length: 1455} {Smed: dd_Smed_v6_32483_0_1, dd_Smed_v6_32483_0_1, [Score=63.2, Expect=6e-12]} {RNA1310_45206} {RNA815_28788}
98. MligTC455_50502 220 4.57 Mlig455_055106

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.948

0.952 - - 0.952 - - - Mlig455_055106 {REF} {Length: 2136} {TRANSSPLICED} {Pfam: HMGL-like [PF00682.21, score=29.9]; EF-hand domain pair [PF13833.8, score=23.0]; EF hand [PF00036.34, score=19.2]} {RNA1509_52740} {RNA1310_12954.1} {RNA815_19505}
99. MligTC455_51357 410 8.55 Mlig455_064530

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.532

ANKRD44 0.952 - - 0.952 - - - Mlig455_064530 {REF} {Length: 2291} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=143.2]; Ankyrin repeats (many copies) [PF13637.8, score=105.0]; Ankyrin repeat [PF13606.8, score=78.0]; Ankyrin repeat [PF00023.32, score=59.6]; Ankyrin repeats (many copies) [PF13857.8, score=55.4]} {Human: ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=79.3, Expect=1e-14]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=75.1, Expect=1e-13]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=53.1, Expect=7e-07]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=71.2, Expect=1e-12]} {Smed: dd_Smed_v6_29517_0_1, dd_Smed_v6_29517_0_1, [Score=56.2, Expect=4e-08]} {RNA1509_26353, RNA1509_26359} {RNA1310_7390.2, RNA1509_26353, RNA1509_26359} {RNA1509_26353, RNA1509_26359, RNA815_20018}
100. MligTC455_37342 203 4.23 Mlig455_024018

Neo: -

Age: -

0.951 - - 0.951 - - - Mlig455_024018 {REF} {Length: 1374} {RNA1509_59718} {RNA1310_33285} {RNA815_22262}

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