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Results for MligTC455_28640

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_28640 1584 33.00 Mlig455_048248

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.826

RNF213 Mlig455_048248 {REF} {Length: 17851} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=28.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.8]; P-loop containing dynein motor region [PF12775.9, score=20.5]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=19.3]} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=1192, Expect=0.0]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=1167, Expect=0.0]} {RNA1509_1262, RNA1509_30585, RNA1509_34013, RNA1509_42379, RNA1509_5517, RNA1509_56737} {RNA1310_22, RNA1509_1262, RNA1509_30585, RNA1509_34013, RNA1509_42379, RNA1509_5517, RNA1509_56737} {RNA1509_1262, RNA1509_30585, RNA1509_34013, RNA1509_42379, RNA1509_5517, RNA1509_56737, RNA815_15}

Cumulative graph for MligTC455_28640

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.271 5.267 0.11692 0.70519
RegionR2 -0.138 5.267 0.66021 0.99255
RegionR3 0.714 5.267 0.00239 0.05665
RegionR4 0.652 5.267 0.03010 0.13622
RegionR5 0.035 5.267 0.87944 1.00000
RegionR6 0.149 5.267 0.55384 1.00000
RegionR7 -0.055 5.267 0.86408 1.00000
RegionR8 -0.086 5.267 0.81706 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 1.473 5.267 0.15010 0.89129
RegenerationR2 -0.007 5.267 0.97816 1.00000
RegenerationR3 -0.925 5.267 0.00082 0.04407
RegenerationR4 -0.715 5.267 0.01598 0.19765
RegenerationR5 -0.262 5.267 0.33093 0.75223
RegenerationR6 -0.497 5.267 0.08983 0.37346
RegenerationBL -0.984 5.267 0.01144 0.10899
RegenerationTP -0.694 5.267 0.07114 0.42765


Genes with expression patterns similar to MligTC455_28640

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_28640 1584 33 Mlig455_048248

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.826

RNF213 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_048248 {REF} {Length: 17851} {TRANSSPLICED} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=28.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=20.8]; P-loop containing dynein motor region [PF12775.9, score=20.5]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=19.3]} {Human: ENSG00000173821, RNF213, ring finger protein 213, [Score=1192, Expect=0.0]} {Mouse: ENSMUSG00000070327, Rnf213, ring finger protein 213, [Score=1167, Expect=0.0]} {RNA1509_1262, RNA1509_30585, RNA1509_34013, RNA1509_42379, RNA1509_5517, RNA1509_56737} {RNA1310_22, RNA1509_1262, RNA1509_30585, RNA1509_34013, RNA1509_42379, RNA1509_5517, RNA1509_56737} {RNA1509_1262, RNA1509_30585, RNA1509_34013, RNA1509_42379, RNA1509_5517, RNA1509_56737, RNA815_15}
2. MligTC455_30555 345 7.18 Mlig455_014294

Neo: -

Age: -

UBE2H 0.979 - - - - 0.979 - Mlig455_014294 {REF} {Length: 4063} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=126.6]} {Human: ENSG00000186591, UBE2H, ubiquitin conjugating enzyme E2 H, [RH, Score=300, Expect=5e-105]} {Mouse: ENSMUSG00000039159, Ube2h, ubiquitin-conjugating enzyme E2H, [RH, Score=300, Expect=3e-105]} {Dmel: FBgn0029996, UbcE2H, Ubiquitin conjugating enzyme E2H, [RH, Score=280, Expect=3e-97]} {Celegans: WBGene00006705, ubc-8, UBiquitin Conjugating enzyme, [RH, Score=249, Expect=1e-84]} {Smed: dd_Smed_v6_4514_0_1, dd_Smed_v6_4514_0_1, [RH, Score=273, Expect=5e-95]} {RNA1509_13844, RNA1509_49595, RNA1509_7917, RNA1509_9318} {RNA1310_31599, RNA1509_13844, RNA1509_49595, RNA1509_7917, RNA1509_9318} {RNA1509_13844, RNA1509_49595, RNA1509_7917, RNA1509_9318, RNA815_15483}
3. MligTC455_09008 32 0.67 Mlig455_013797

Neo: -

Age: -

0.971 - - - - 0.971 - Mlig455_013797 {REF} {Length: 837} {NoTransDecoderORF} {RNA1310_108364}
4. MligTC455_42121 828 17.25 Mlig455_020232

Neo: -

Age: -

MOB2 0.964 - - - - 0.964 - Mlig455_020232 {REF} {Length: 1206} {TRANSSPLICED} {Pfam: Mob1/phocein family [PF03637.19, score=113.6]} {Human: ENSG00000182208, MOB2, MOB kinase activator 2, [Score=110, Expect=5e-29]} {Mouse: ENSMUSG00000006262, Mob1b, MOB kinase activator 1B, [Score=89.7, Expect=1e-21]; ENSMUSG00000043131, Mob1a, MOB kinase activator 1A, [Score=88.2, Expect=5e-21]} {Dmel: FBgn0259482, Mob3, MOB kinase activator 3, [Score=78.6, Expect=2e-17]} {Celegans: WBGene00020447, mob-3, [Score=75.5, Expect=4e-16]} {Smed: dd_Smed_v6_13787_0_1, dd_Smed_v6_13787_0_1, [RH, Score=132, Expect=5e-38]} {RNA1509_25220, RNA1509_54726} {RNA1310_20183.2, RNA1509_25220, RNA1509_54726} {RNA1509_25220, RNA1509_54726, RNA815_10855.1}
5. MligTC455_32796 106 2.21 Mlig455_059824

Neo: Int S/G2/M

Age: -

0.963 - - - - 0.963 - Mlig455_059824 {REF} {Length: 1634} {TRANSSPLICED} {RNA1509_48912} {RNA1310_29994} {RNA815_2705}
6. MligTC455_16914 102 2.13 Mlig455_064269

Neo: -

Age: Up-Down-Down

ACVR2A 0.962 - - - - 0.962 - Mlig455_064269 {REF} {Length: 3504} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=123.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=116.9]; Fungal protein kinase [PF17667.3, score=23.7]} {Human: ENSG00000121989, ACVR2A, activin A receptor type 2A, [RH, Score=317, Expect=9e-103]} {Mouse: ENSMUSG00000052155, Acvr2a, activin receptor IIA, [RH, Score=316, Expect=4e-101]} {Dmel: FBgn0003169, put, punt, [RH, Score=302, Expect=9e-96]} {Celegans: WBGene00000897, daf-1, Cell surface receptor daf-1, [Score=195, Expect=3e-54]} {Smed: dd_Smed_v6_8124_0_1, dd_Smed_v6_8124_0_1, [RH, Score=216, Expect=8e-63]} {RNA1509_49081, RNA1509_6898} {RNA1310_269.1, RNA1509_49081} {RNA1509_49081, RNA815_7753}
7. MligTC455_17684 157 3.26 Mlig455_041455

Neo: Irradiation

Age: Up-Down-Down

ASPG 0.96 - - - - 0.960 - Mlig455_041455 {REF} {Length: 5938} {TRANSSPLICED} {Pfam: Asparaginase, N-terminal [PF00710.22, score=202.1]; Glutaminase/Asparaginase C-terminal domain [PF17763.3, score=84.6]; Ankyrin repeats (many copies) [PF13857.8, score=64.3]; Ankyrin repeats (3 copies) [PF12796.9, score=59.0]; Ankyrin repeats (many copies) [PF13637.8, score=54.0]; Ankyrin repeat [PF13606.8, score=43.8]; Ankyrin repeat [PF00023.32, score=35.8]} {Human: ENSG00000166183, ASPG, asparaginase, [Score=346, Expect=7e-110]} {Mouse: ENSMUSG00000037686, Aspg, asparaginase, [Score=340, Expect=9e-108]} {Dmel: FBgn0029689, CG6428, [RH, Score=439, Expect=2e-145]} {Celegans: WBGene00007756, C27A7.5, [Score=412, Expect=1e-134]} {Smed: dd_Smed_v6_7816_0_1, dd_Smed_v6_7816_0_1, [RH, Score=426, Expect=7e-140]} {RNA1509_11582, RNA1509_16816, RNA1509_8667} {RNA1310_8678, RNA1509_16816, RNA1509_8667} {RNA1509_16816, RNA1509_8667, RNA815_6302}
8. MligTC455_20294 341 7.11 Mlig455_007896, Mlig455_008003

Neo: -

Age: Up-Down-Down

Region-enriched R8: 3.032/0.04842

LRRK2 0.96 - - - - 0.960 -

Mlig455_007896 {REF} {Length: 11344} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=164.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=71.6]; TIR domain [PF13676.8, score=57.4]; Leucine rich repeat [PF13855.8, score=43.0]; Ras family [PF00071.24, score=38.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=24.8]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=3e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=166, Expect=5e-40]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=7e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=125, Expect=4e-28]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=723, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1, RNA1509_8727} {RNA1509_8727, RNA815_1320}

Mlig455_008003 {REF} {Length: 11209} {TRANSSPLICED} {Pfam: C-terminal of Roc, COR, domain [PF16095.7, score=160.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.4]; TIR domain [PF13676.8, score=59.5]; Leucine rich repeat [PF13855.8, score=45.2]; Ras family [PF00071.24, score=39.6]; Leucine Rich repeats (2 copies) [PF12799.9, score=28.4]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [Score=167, Expect=1e-40]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [Score=163, Expect=1e-39]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=145, Expect=4e-34]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=120, Expect=1e-26]} {Smed: dd_Smed_v6_12105_0_1, dd_Smed_v6_12105_0_1, [Score=686, Expect=0.0]} {RNA1509_8727} {RNA1310_292.1} {RNA815_1320}
9. MligTC455_26512 128 2.67 Mlig455_069089

Neo: -

Age: Up-Down-Down

PRKDC 0.96 - - - - 0.960 - Mlig455_069089 {REF} {Length: 15905} {Pfam: NUC194 domain [PF08163.14, score=230.9]; DNA-PKcs, CC5 [PF19704.1, score=218.9]; Phosphatidylinositol 3- and 4-kinase [PF00454.29, score=139.7]; FAT domain [PF02259.25, score=33.6]; FATC domain [PF02260.22, score=27.0]; DDE superfamily endonuclease [PF13358.8, score=24.7]; Helix-turn-helix domain [PF13518.8, score=22.8]} {Human: ENSG00000253729, PRKDC, protein kinase, DNA-activated, catalytic subunit, [Score=652, Expect=0.0]} {Mouse: ENSMUSG00000022672, Prkdc, protein kinase, DNA activated, catalytic polypeptide, [Score=624, Expect=1e-178]} {Dmel: FBgn0021796, Tor, Target of rapamycin, [Score=152, Expect=8e-36]} {Celegans: WBGene00002583, let-363, Target of rapamycin homolog, [Score=149, Expect=3e-35]} {Smed: dd_Smed_v6_8462_0_2, dd_Smed_v6_8462_0_2, [RH, Score=284, Expect=5e-76]} {RNA1509_11402, RNA1509_47977, RNA1509_60024} {RNA1310_372, RNA1509_47977, RNA1509_60024} {RNA1509_47977, RNA1509_60024, RNA815_3968}
10. MligTC455_27796 664 13.84 Mlig455_005664

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.450

HELZ2 0.957 - - - - 0.957 - Mlig455_005664 {REF} {Length: 8120} {Pfam: RNB domain [PF00773.21, score=158.5]; AAA domain [PF13086.8, score=134.0]; AAA domain [PF13087.8, score=128.8]; AAA domain [PF13604.8, score=26.8]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=21.9]; UvrD-like helicase C-terminal domain [PF13361.8, score=19.7]; UvrD-like helicase C-terminal domain [PF13538.8, score=19.6]} {Human: ENSG00000130589, HELZ2, helicase with zinc finger 2, [Score=148, Expect=6e-35]} {Mouse: ENSMUSG00000027580, Helz2, helicase with zinc finger 2, transcriptional coactivator, [Score=146, Expect=3e-34]} {Dmel: FBgn0039183, Dis3, [Score=110, Expect=8e-24]} {Celegans: WBGene00018612, disl-2, DIS3-like exonuclease 2, [Score=103, Expect=8e-22]} {Smed: dd_Smed_v6_8176_0_1, dd_Smed_v6_8176_0_1, [RH, Score=326, Expect=7e-90]} {RNA1509_18632} {RNA1310_275} {RNA815_982.1}
11. MligTC455_19164 643 13.39 Mlig455_066812

Neo: -

Age: -

TBL2 0.956 - - - - 0.956 - Mlig455_066812 {REF} {Length: 2791} {Pfam: WD domain, G-beta repeat [PF00400.34, score=72.6]} {Human: ENSG00000106638, TBL2, transducin beta like 2, [RH, Score=296, Expect=4e-96]} {Mouse: ENSMUSG00000005374, Tbl2, transducin (beta)-like 2, [RH, Score=283, Expect=2e-90]} {Dmel: FBgn0032030, Wdr82, WD repeat domain 82, [Score=51.2, Expect=9e-07]} {Celegans: WBGene00009784, F46C5.9, [RH, Score=174, Expect=5e-49]} {Smed: dd_Smed_v6_4372_0_1, dd_Smed_v6_4372_0_1, [RH, Score=249, Expect=1e-77]} {RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1310_11971, RNA1509_12484, RNA1509_27098, RNA1509_8303} {RNA1509_12484, RNA1509_27098, RNA1509_8303, RNA815_4594}
12. MligTC455_12312 158 3.3 Mlig455_020134, Mlig455_045030

Neo: -

Age: -

SYT7 0.954 - - - - 0.954 -

Mlig455_020134 {REF} {Length: 2000} {Pfam: C2 domain [PF00168.32, score=69.8]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [Score=130, Expect=1e-31]} {Mouse: ENSMUSG00000024743, Syt7, synaptotagmin VII, [Score=119, Expect=2e-28]; ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=116, Expect=1e-27]; ENSMUSG00000026452, Syt2, synaptotagmin II, [Score=116, Expect=8e-28]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [Score=157, Expect=5e-42]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=116, Expect=3e-28]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=115, Expect=2e-28]} {RNA1509_46689} {RNA1310_12025} {RNA815_31022}

Mlig455_045030 {REF} {Length: 3640} {Pfam: C2 domain [PF00168.32, score=110.2]} {Human: ENSG00000011347, SYT7, synaptotagmin 7, [Score=169, Expect=6e-45]; ENSG00000143858, SYT2, synaptotagmin 2, [Score=164, Expect=9e-45]; ENSG00000170743, SYT9, synaptotagmin 9, [Score=163, Expect=6e-44]} {Mouse: ENSMUSG00000026452, Syt2, synaptotagmin II, [Score=164, Expect=7e-45]; ENSMUSG00000062542, Syt9, synaptotagmin IX, [Score=164, Expect=2e-44]; ENSMUSG00000024743, Syt7, synaptotagmin VII, [Score=158, Expect=9e-42]} {Dmel: FBgn0261089, Sytalpha, Synaptotagmin alpha, [RH, Score=202, Expect=2e-58]} {Celegans: WBGene00004921, snt-1, Synaptotagmin-1, [Score=153, Expect=6e-41]} {Smed: dd_Smed_v6_4222_0_1, dd_Smed_v6_4222_0_1, [Score=160, Expect=5e-44]} {RNA1509_46689} {RNA1310_12025} {RNA815_31022}
13. MligTC455_15038 250 5.21 Mlig455_063064

Neo: Int S/G2/M

Age: -

0.954 - - - - 0.954 - Mlig455_063064 {REF} {Length: 2533} {TRANSSPLICED} {tRNA: Undet(NNN),pseudo, score=20.4} {Pfam: Lysine methyltransferase [PF10294.11, score=66.3]} {Mouse: ENSMUSG00000090266, Mettl23, methyltransferase like 23, [RH, Score=51.6, Expect=7e-07]} {Dmel: FBgn0038396, CG5013, [Score=50.8, Expect=9e-07]} {Smed: dd_Smed_v6_7520_0_1, dd_Smed_v6_7520_0_1, [RH, Score=67.8, Expect=8e-13]} {RNA1509_53043} {RNA1310_32954} {RNA815_28785}
14. MligTC455_17325 946 19.7 Mlig455_020480

Neo: -

Age: Down-Up-Up

Region-enriched R5: 2.284/0.00000
Region-enriched R4: 1.716/0.03979

0.954 - - - - 0.954 - Mlig455_020480 {REF} {Length: 922} {TRANSSPLICED} {RNA1509_31242} {RNA1310_36884, RNA1509_31242} {RNA1509_31242, RNA815_22323}
15. MligTC455_23795 429 8.94 Mlig455_001192

Neo: -

Age: Up-Down-Up

0.951 - - - - 0.951 - Mlig455_001192 {REF} {Length: 607} {NoTransDecoderORF} {RNA1509_41106} {RNA1310_59119} {RNA815_35957}
16. MligTC455_50331 348 7.26 Mlig455_045355

Neo: Irradiation

Age: Up-Down-Down

Region-enriched R2: 1.911/0.04277
Region-enriched R5: 1.493/0.00190

TGFBR1 0.95 - - - - 0.950 - Mlig455_045355 {REF} {Length: 2444} {Pfam: Protein kinase domain [PF00069.27, score=69.2]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=68.4]; ABC1 atypical kinase-like domain [PF03109.18, score=32.2]; Transforming growth factor beta type I GS-motif [PF08515.14, score=20.5]} {Human: ENSG00000106799, TGFBR1, transforming growth factor beta receptor 1, [Score=180, Expect=8e-51]; ENSG00000135503, ACVR1B, activin A receptor type 1B, [Score=174, Expect=1e-48]} {Mouse: ENSMUSG00000007613, Tgfbr1, transforming growth factor, beta receptor I, [Score=181, Expect=1e-51]; ENSMUSG00000000532, Acvr1b, activin A receptor, type 1B, [Score=174, Expect=2e-48]} {Dmel: FBgn0011300, babo, baboon, [Score=180, Expect=5e-50]} {Celegans: WBGene00000897, daf-1, Cell surface receptor daf-1, [Score=142, Expect=4e-36]} {Smed: dd_Smed_v6_3426_0_1, dd_Smed_v6_3426_0_1, [Score=177, Expect=8e-49]} {RNA1509_17304, RNA1509_34135} {RNA1310_10744, RNA1509_34135} {RNA1509_34135, RNA815_11070}

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