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Results for MligTC455_30094

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_30094 4128 86.01 Mlig455_015674, Mlig455_062483

Neo: -

Age: Down-Down-Up

Mlig455_015674 {REF} {Length: 3057} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=126.7]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [Score=421, Expect=4e-138]} {RNA1509_3901} {RNA1310_1179.2} {RNA815_296.2}

Mlig455_062483 {REF} {Length: 3106} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=125.5]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [RH, Score=486, Expect=1e-161]} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1310_1179.1, RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971, RNA815_296.2}

Cumulative graph for MligTC455_30094

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.695 6.512 0.19105 0.82486
RegionR2 -0.871 6.512 0.00779 0.08606
RegionR3 0.085 6.512 0.74717 1.00000
RegionR4 0.54 6.512 0.07881 0.26227
RegionR5 -0.106 6.512 0.68439 1.00000
RegionR6 0.029 6.512 0.91446 1.00000
RegionR7 -0.248 6.512 0.43523 1.00000
RegionR8 -0.126 6.512 0.74732 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.94 6.512 0.19795 0.93767
RegenerationR2 -0.166 6.512 0.61669 0.92221
RegenerationR3 0.138 6.512 0.67831 0.93964
RegenerationR4 0.109 6.512 0.74786 0.96971
RegenerationR5 0.371 6.512 0.25930 0.69096
RegenerationR6 0.298 6.512 0.36742 0.71057
RegenerationBL -0.655 6.512 0.06211 0.28937
RegenerationTP -0.074 6.512 0.84041 1.00000


Genes with expression patterns similar to MligTC455_30094

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_30094 4128 86.01 Mlig455_015674, Mlig455_062483

Neo: -

Age: Down-Down-Up

6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_015674 {REF} {Length: 3057} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=126.7]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [Score=421, Expect=4e-138]} {RNA1509_3901} {RNA1310_1179.2} {RNA815_296.2}

Mlig455_062483 {REF} {Length: 3106} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=125.5]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [RH, Score=486, Expect=1e-161]} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1310_1179.1, RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971, RNA815_296.2}
2. MligTC455_38363 2457 51.19 Mlig455_045500, Mlig455_065739

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.377

Region-enriched R3: 1.866/0.00436
Region-enriched R6: 1.855/0.01251
Region-enriched R5: 1.276/0.04355

Regeneration-upregulated TP: 3.564

Regeneration-enriched TP: 3.564

AADAC 3.288 0.719 - - 0.966 0.768 0.835

Mlig455_045500 {REF} {Length: 2281} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.9]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=7e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=114, Expect=1e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.4, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=6e-28]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1, RNA1509_7598} {RNA1509_7598, RNA815_8354}

Mlig455_065739 {REF} {Length: 1875} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.8]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=8e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=113, Expect=2e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.0, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1} {RNA815_8354}
3. MligTC455_36156 1967 40.98 Mlig455_060763

Neo: -

Age: -

Region-enriched R4: 1.369/0.00850
Region-enriched R3: 1.338/0.00253

CNTNAP5 2.66 - - - 0.916 0.955 0.789 Mlig455_060763 {REF} {Length: 4809} {Pfam: Laminin G domain [PF02210.26, score=234.3]; Laminin G domain [PF00054.25, score=157.1]; F5/8 type C domain [PF00754.27, score=88.7]; Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=31.8]; EGF-like domain [PF00008.29, score=27.2]} {Human: ENSG00000155052, CNTNAP5, contactin associated protein like 5, [RH, Score=534, Expect=2e-166]; ENSG00000174469, CNTNAP2, contactin associated protein like 2, [RH, Score=531, Expect=5e-165]} {Mouse: ENSMUSG00000039419, Cntnap2, contactin associated protein-like 2, [RH, Score=521, Expect=2e-161]; ENSMUSG00000070695, Cntnap5a, contactin associated protein-like 5A, [RH, Score=500, Expect=4e-154]} {Dmel: FBgn0013997, Nrx-IV, Neurexin IV, [RH, Score=684, Expect=0.0]} {Celegans: WBGene00003772, nlr-1, Neurexin Like receptor, [Score=226, Expect=4e-60]} {Smed: dd_Smed_v6_2622_0_1, dd_Smed_v6_2622_0_1, [RH, Score=1080, Expect=0.0]} {RNA1509_14063, RNA1509_27222, RNA1509_39677, RNA1509_962} {RNA1310_1572.1, RNA1509_14063, RNA1509_27222, RNA1509_39677, RNA1509_962} {RNA1509_14063, RNA1509_27222, RNA1509_39677, RNA1509_962, RNA815_442.1}
4. MligTC455_16658 1547 32.23 Mlig455_056718, Mlig455_060300

Neo: -

Age: -

Region-enriched R3: 1.971/0.00155
Region-enriched R4: 1.653/0.02745

2.642 - - - 0.895 0.962 0.785

Mlig455_056718 {REF} {Length: 1714} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=44.7]} {RNA1509_50620, RNA1509_51103, RNA1509_8737} {RNA1310_8838, RNA1509_50620, RNA1509_51103} {RNA1509_50620, RNA1509_51103, RNA815_7244}

Mlig455_060300 {REF} {Length: 1815} {Pfam: Endonuclease/Exonuclease/phosphatase family [PF03372.25, score=46.9]} {Smed: dd_Smed_v6_855_0_1, dd_Smed_v6_855_0_1, [Score=47.0, Expect=5e-06]} {RNA1509_8737} {RNA1310_8838, RNA1509_8737} {RNA1509_8737, RNA815_7244}
5. MligTC455_33836 2065 43.02 Mlig455_036757

Neo: -

Age: logFC(26M/2M)=-0.242

Region-enriched R3: 1.925/0.00000
Region-enriched R4: 1.200/0.01490
Region-enriched R5: 1.020/0.01114

CYP2J2 2.641 - - - 0.895 0.953 0.793 Mlig455_036757 {REF} {Length: 1902} {Pfam: Cytochrome P450 [PF00067.24, score=314.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=252, Expect=2e-77]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=248, Expect=4e-76]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=248, Expect=4e-76]; ENSMUSG00000081362, Cyp2j7, cytochrome P450, family 2, subfamily j, polypeptide 7, [Score=246, Expect=3e-75]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=246, Expect=2e-75]; ENSMUSG00000066097, Cyp2j11, cytochrome P450, family 2, subfamily j, polypeptide 11, [Score=240, Expect=7e-73]; ENSMUSG00000015224, Cyp2j9, cytochrome P450, family 2, subfamily j, polypeptide 9, [Score=239, Expect=1e-72]; ENSMUSG00000082932, Cyp2j8, cytochrome P450, family 2, subfamily j, polypeptide 8, [Score=236, Expect=2e-71]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=208, Expect=1e-60]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=226, Expect=7e-68]} {Smed: dd_Smed_v6_5344_0_2, dd_Smed_v6_5344_0_2, [RH, Score=260, Expect=8e-81]} {RNA1509_32471} {RNA1310_10330} {RNA815_3898.1}
6. MligTC455_43133 2633 54.86 Mlig455_033697, Mlig455_050134

Neo: -

Age: -

Region-enriched R3: 2.075/0.00231
Region-enriched R4: 1.915/0.02367

ENPP5 2.582 - - - 0.966 0.798 0.818

Mlig455_033697 {REF} {Length: 1895} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=202.8]; Sulfatase [PF00884.25, score=38.8]; Protein of unknown function (DUF1501) [PF07394.14, score=23.7]; Metalloenzyme superfamily [PF01676.20, score=18.8]} {Human: ENSG00000112796, ENPP5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative), [Score=207, Expect=8e-60]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [Score=198, Expect=1e-56]} {Mouse: ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [Score=209, Expect=1e-60]} {Celegans: WBGene00015283, C01B10.9, [RH, Score=160, Expect=1e-42]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [Score=180, Expect=5e-50]} {RNA1509_8220} {RNA1310_19894.1} {RNA815_8419}

Mlig455_050134 {REF} {Length: 1895} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=201.5]; Sulfatase [PF00884.25, score=38.5]; Protein of unknown function (DUF1501) [PF07394.14, score=21.0]; Metalloenzyme superfamily [PF01676.20, score=18.3]} {Human: ENSG00000112796, ENPP5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative), [Score=206, Expect=2e-59]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [Score=197, Expect=2e-56]} {Mouse: ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [Score=208, Expect=2e-60]} {Celegans: WBGene00015283, C01B10.9, [RH, Score=160, Expect=2e-42]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [Score=179, Expect=1e-49]} {RNA1509_8220} {RNA1310_19894.1} {RNA815_8419}
7. MligTC455_31506 586 12.2 Mlig455_059744

Neo: -

Age: -

Region-enriched R4: 2.875/0.00022
Region-enriched R3: 2.468/0.00160
Region-enriched R5: 2.189/0.00308

DDO 2.569 - - - 0.903 0.954 0.712 Mlig455_059744 {REF} {Length: 2018} {Pfam: FAD dependent oxidoreductase [PF01266.26, score=129.1]} {Human: ENSG00000203797, DDO, D-aspartate oxidase, [RH, Score=218, Expect=1e-67]; ENSG00000110887, DAO, D-amino acid oxidase, [RH, Score=209, Expect=1e-64]} {Mouse: ENSMUSG00000042096, Dao, D-amino acid oxidase, [RH, Score=216, Expect=3e-67]; ENSMUSG00000063428, Ddo, D-aspartate oxidase, [RH, Score=216, Expect=1e-67]} {Dmel: FBgn0031860, CG11236, [RH, Score=211, Expect=6e-66]} {Celegans: WBGene00022076, daao-1, D-amino-acid oxidase, [Score=174, Expect=1e-51]} {Smed: dd_Smed_v6_3560_0_1, dd_Smed_v6_3560_0_1, [RH, Score=246, Expect=2e-79]} {RNA1509_1569} {RNA1310_11182} {RNA815_6961}
8. MligTC455_39170 3221 67.1 Mlig455_038903

Neo: -

Age: logFC(26M/2M)=0.340

Region-enriched R3: 2.495/0.00000
Region-enriched R4: 1.609/0.00501
Region-enriched R5: 1.221/0.00810

ALDH2 2.561 - - - 0.813 0.961 0.787 Mlig455_038903 {REF} {Length: 2307} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=593.4]} {Human: ENSG00000111275, ALDH2, aldehyde dehydrogenase 2 family member, [RH, Score=780, Expect=0.0]; ENSG00000137124, ALDH1B1, aldehyde dehydrogenase 1 family member B1, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000029455, Aldh2, aldehyde dehydrogenase 2, mitochondrial, [RH, Score=768, Expect=0.0]; ENSMUSG00000035561, Aldh1b1, aldehyde dehydrogenase 1 family, member B1, [RH, Score=749, Expect=0.0]} {Dmel: FBgn0012036, Aldh, Aldehyde dehydrogenase, [RH, Score=718, Expect=0.0]} {Celegans: WBGene00000107, alh-1, ALdehyde deHydrogenase, [RH, Score=725, Expect=0.0]} {Smed: dd_Smed_v6_1339_0_1, dd_Smed_v6_1339_0_1, [RH, Score=725, Expect=0.0]} {RNA1509_1186} {RNA1310_3799.1} {RNA815_1286.1}
9. MligTC455_48360 594 12.37 Mlig455_034363

Neo: -

Age: -

Region-enriched R3: 2.361/0.00279
Region-enriched R4: 2.128/0.02443

2.479 - - 0.719 - 0.952 0.808 Mlig455_034363 {REF} {Length: 3889} {Pfam: Death domain [PF00531.24, score=30.1]} {Celegans: WBGene00002041, hum-8, Heavy chain, Unconventional Myosin, [Score=50.4, Expect=6e-06]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [Score=105, Expect=3e-23]} {RNA1509_29690, RNA1509_59375} {RNA1310_5206.1, RNA1509_59375} {RNA1509_59375, RNA815_3494}
10. MligTC455_38469 2237 46.61 Mlig455_028190, Mlig455_063554

Neo: -

Age: logFC(26M/2M)=0.551

Region-enriched R4: 2.765/0.00002
Region-enriched R3: 2.517/0.00000
Region-enriched R5: 1.859/0.00156

MFSD2A 2.452 - - 0.743 - 0.953 0.756

Mlig455_028190 {REF} {Length: 1877} {Pfam: MFS/sugar transport protein [PF13347.8, score=314.5]; Major Facilitator Superfamily [PF07690.18, score=35.3]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=317, Expect=2e-101]} {Mouse: ENSMUSG00000028655, Mfsd2a, major facilitator superfamily domain containing 2A, [RH, Score=312, Expect=2e-99]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [RH, Score=380, Expect=3e-126]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}

Mlig455_063554 {REF} {Length: 2339} {Pfam: MFS/sugar transport protein [PF13347.8, score=217.9]; Major Facilitator Superfamily [PF07690.18, score=39.9]} {Human: ENSG00000168389, MFSD2A, major facilitator superfamily domain containing 2A, [RH, Score=223, Expect=1e-68]} {Mouse: ENSMUSG00000037336, Mfsd2b, major facilitator superfamily domain containing 2B, [RH, Score=212, Expect=2e-64]} {Smed: dd_Smed_v6_11210_0_1, dd_Smed_v6_11210_0_1, [Score=274, Expect=8e-87]} {RNA1509_5264} {RNA1310_14549} {RNA815_5531}
11. MligTC455_25001 1133 23.6 Mlig455_065966

Neo: -

Age: -

Region-enriched R3: 1.365/0.01349

NPR1 1.876 - - - 0.920 0.956 - Mlig455_065966 {REF} {Length: 5635} {Pfam: Adenylate and Guanylate cyclase catalytic domain [PF00211.22, score=224.6]; Receptor family ligand binding region [PF01094.30, score=135.1]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=124.4]; Protein kinase domain [PF00069.27, score=108.1]} {Human: ENSG00000169418, NPR1, natriuretic peptide receptor 1, [Score=629, Expect=0.0]; ENSG00000159899, NPR2, natriuretic peptide receptor 2, [Score=622, Expect=0.0]} {Mouse: ENSMUSG00000028469, Npr2, natriuretic peptide receptor 2, [RH, Score=624, Expect=0.0]} {Dmel: FBgn0051183, CG31183, [Score=588, Expect=0.0]} {Celegans: WBGene00020131, gcy-28, Receptor-type guanylate cyclase gcy-28, [Score=593, Expect=0.0]} {Smed: dd_Smed_v6_7619_0_1, dd_Smed_v6_7619_0_1, [Score=848, Expect=0.0]} {RNA1509_8882} {RNA1310_1175.2} {RNA815_737}
12. MligTC455_37466 1949 40.61 Mlig455_031186

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.619/0.00008

ARHGEF10 1.864 - - - 0.891 0.973 - Mlig455_031186 {REF} {Length: 5352} {Pfam: RhoGEF domain [PF00621.22, score=105.9]; WD40 repeated domain [PF19056.2, score=87.7]; PH domain [PF19057.2, score=32.3]} {Human: ENSG00000274726, ARHGEF10, Rho guanine nucleotide exchange factor 10, [RH, Score=289, Expect=7e-80]; ENSG00000104728, ARHGEF10, Rho guanine nucleotide exchange factor 10, [RH, Score=289, Expect=7e-80]} {Mouse: ENSMUSG00000071176, Arhgef10, Rho guanine nucleotide exchange factor (GEF) 10, [RH, Score=301, Expect=5e-84]} {Dmel: FBgn0263706, CG43658, [RH, Score=249, Expect=8e-67]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [Score=115, Expect=1e-25]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [Score=112, Expect=7e-25]} {RNA1509_2853} {RNA1310_2593.1} {RNA815_1265}
13. MligTC455_44838 1113 23.18 Mlig455_035218, Mlig455_035266

Neo: -

Age: -

MAN2B1 1.841 - - - 0.964 - 0.877

Mlig455_035218 {REF} {Length: 3151} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=269.2]; Alpha mannosidase middle domain [PF09261.13, score=64.9]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=44.0]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.3]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=630, Expect=0.0]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=607, Expect=0.0]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=636, Expect=0.0]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [RH, Score=502, Expect=9e-163]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=674, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1, RNA1509_7785} {RNA1509_7785, RNA815_7617}

Mlig455_035266 {REF} {Length: 2979} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=189.2]; Alpha mannosidase middle domain [PF09261.13, score=64.8]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=45.6]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.4]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=531, Expect=1e-173]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=501, Expect=6e-162]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=538, Expect=2e-175]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [Score=428, Expect=4e-135]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=566, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1} {RNA815_7617}
14. MligTC455_45317 7239 150.81 Mlig455_037737, Mlig455_037806

Neo: -

Age: -

1.84 - - - - 0.963 0.877

Mlig455_037737 {REF} {Length: 2604} {RNA1509_1424, RNA1509_53437, RNA1509_9976} {RNA1310_9473.1, RNA1509_1424, RNA1509_53437, RNA1509_9976} {RNA1509_1424, RNA1509_53437, RNA1509_9976, RNA815_4341.1}

Mlig455_037806 {REF} {Length: 2442} {RNA1509_20048, RNA1509_26966, RNA1509_8140, RNA1509_9976} {RNA1310_9473.1, RNA1509_20048, RNA1509_26966, RNA1509_8140} {RNA1509_20048, RNA1509_26966, RNA1509_8140, RNA815_4341.1}
15. MligTC455_18925 1222 25.47 Mlig455_034430

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.749/0.00485

RGS12 1.82 - - - - 0.965 0.855 Mlig455_034430 {REF} {Length: 1569} {Pfam: Regulator of G protein signaling domain [PF00615.21, score=98.3]} {Human: ENSG00000159788, RGS12, regulator of G protein signaling 12, [Score=112, Expect=3e-26]; ENSG00000169220, RGS14, regulator of G protein signaling 14, [Score=110, Expect=6e-26]} {Mouse: ENSMUSG00000052087, Rgs14, regulator of G-protein signaling 14, [RH, Score=114, Expect=2e-27]} {Dmel: FBgn0020278, loco, locomotion defects, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00004347, rgs-4, Regulator of G protein Signaling, [Score=82.8, Expect=3e-18]} {Smed: dd_Smed_v6_3873_0_1, dd_Smed_v6_3873_0_1, [Score=95.5, Expect=3e-23]} {RNA1509_7258} {RNA1310_21231} {RNA815_8874}
16. MligTC455_40926 680 14.16 Mlig455_029450, Mlig455_029472

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.535/0.00634
Region-enriched R3: 2.023/0.02088

OTOF 1.816 - - - - 0.962 0.854

Mlig455_029450 {REF} {Length: 7011} {Pfam: C2 domain [PF00168.32, score=238.1]; Ferlin C-terminus [PF16165.7, score=107.1]; FerB (NUC096) domain [PF08150.14, score=73.3]; FerI (NUC094) domain [PF08151.14, score=62.3]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=847, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=845, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=324, Expect=3e-89]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=145, Expect=3e-34]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1229, Expect=0.0]} {RNA1509_44062, RNA1509_58476} {RNA1310_427.1, RNA1509_44062} {RNA1509_44062, RNA815_1463}

Mlig455_029472 {REF} {Length: 6996} {Pfam: C2 domain [PF00168.32, score=238.4]; Ferlin C-terminus [PF16165.7, score=107.1]; FerB (NUC096) domain [PF08150.14, score=73.4]; FerI (NUC094) domain [PF08151.14, score=62.3]} {Human: ENSG00000115155, OTOF, otoferlin, [Score=849, Expect=0.0]} {Mouse: ENSMUSG00000062372, Otof, otoferlin, [Score=846, Expect=0.0]} {Dmel: FBgn0266757, mfr, misfire, [RH, Score=324, Expect=3e-89]} {Celegans: WBGene00001414, fer-1, Sperm vesicle fusion protein fer-1, [Score=145, Expect=3e-34]} {Smed: dd_Smed_v6_5915_0_1, dd_Smed_v6_5915_0_1, [Score=1231, Expect=0.0]} {RNA1509_58476} {RNA1310_427.1, RNA1509_58476} {RNA1509_58476, RNA815_1463}
17. MligTC455_45333 5039 104.98 Mlig455_024662, Mlig455_048643, Mlig455_068867

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.566/0.00006
Region-enriched R3: 1.419/0.00002

LIPA 1.812 - - - - 0.973 0.839

Mlig455_024662 {REF} {Length: 2228} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_048643 {REF} {Length: 2232} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}

Mlig455_068867 {REF} {Length: 4154} {TRANSSPLICED} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=85.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=52.3]; Serine aminopeptidase, S33 [PF12146.10, score=42.7]; Alpha/beta hydrolase family [PF12697.9, score=29.3]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=325, Expect=3e-100]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=324, Expect=2e-99]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=313, Expect=8e-96]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=322, Expect=3e-99]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=317, Expect=3e-97]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=309, Expect=3e-94]} {Dmel: FBgn0030052, CG12065, [RH, Score=276, Expect=6e-80]} {Celegans: WBGene00010062, lipl-1, Lipase, [RH, Score=295, Expect=2e-89]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=361, Expect=6e-114]} {RNA1509_16913} {RNA1310_10300.2} {RNA815_4697}
18. MligTC455_45334 2178 45.38 Mlig455_068883

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.795/0.00015
Region-enriched R3: 1.326/0.00189
Region-enriched R5: 1.022/0.01242

LIPA 1.796 - - - - 0.969 0.827 Mlig455_068883 {REF} {Length: 2253} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=88.7]; Partial alpha/beta-hydrolase lipase region [PF04083.18, score=54.0]; Serine aminopeptidase, S33 [PF12146.10, score=47.6]; Alpha/beta hydrolase family [PF12697.9, score=30.4]} {Human: ENSG00000107798, LIPA, lipase A, lysosomal acid type, [RH, Score=323, Expect=2e-106]; ENSG00000182333, LIPF, lipase F, gastric type, [RH, Score=322, Expect=5e-106]; ENSG00000204021, LIPK, lipase family member K, [RH, Score=312, Expect=3e-102]} {Mouse: ENSMUSG00000024781, Lipa, lysosomal acid lipase A, [RH, Score=320, Expect=2e-105]; ENSMUSG00000024768, Lipf, lipase, gastric, [RH, Score=315, Expect=1e-103]; ENSMUSG00000056078, Lipm, lipase, family member M, [RH, Score=308, Expect=1e-100]} {Dmel: FBgn0032264, Lip4, Lipase 4, [RH, Score=265, Expect=1e-83]} {Celegans: WBGene00021963, lipl-6, LIPase Like, [RH, Score=295, Expect=9e-94]} {Smed: dd_Smed_v6_257_0_1, dd_Smed_v6_257_0_1, [RH, Score=360, Expect=2e-121]} {RNA1509_16913, RNA1509_19422, RNA1509_39468} {RNA1310_10300.2, RNA1509_16913, RNA1509_19422, RNA1509_39468} {RNA1509_16913, RNA1509_19422, RNA1509_39468, RNA815_4697}
19. MligTC455_41503 3372 70.25 Mlig455_015421

Neo: -

Age: -

Region-enriched R3: 1.663/0.00123

1.777 - - - - 0.973 0.804 Mlig455_015421 {REF} {Length: 3377} {Pfam: Fasciclin domain [PF02469.24, score=41.0]} {Dmel: FBgn0032638, SPH93, Serine protease homolog 93, [Score=61.6, Expect=2e-09]} {RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1310_8987, RNA1509_26815, RNA1509_27548, RNA1509_56488} {RNA1509_26815, RNA1509_27548, RNA1509_56488, RNA815_3084.1}
20. MligTC455_20618 1076 22.42 Mlig455_044808

Neo: -

Age: logFC(26M/2M)=-0.260

Region-enriched R4: 2.047/0.01278

SLC24A5 1.771 - - - - 0.953 0.818 Mlig455_044808 {REF} {Length: 2975} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_11724, RNA1509_31011, RNA1509_4708} {RNA1310_7971.1, RNA1509_11724, RNA1509_31011, RNA1509_4708} {RNA1509_11724, RNA1509_31011, RNA1509_4708, RNA815_7327}
21. MligTC455_38061 112 2.33 Mlig455_003183, Mlig455_003385

Neo: -

Age: Down-Up-Down

Region-enriched R4: 3.963/0.00323
Region-enriched R3: 2.923/0.03513

SLC22A5 1.691 - - - - 0.728 0.963

Mlig455_003183 {REF} {Length: 2030} {Pfam: Sugar (and other) transporter [PF00083.26, score=94.4]; Major Facilitator Superfamily [PF07690.18, score=79.2]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=251, Expect=1e-75]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=247, Expect=3e-74]} {Mouse: ENSMUSG00000020334, Slc22a4, solute carrier family 22 (organic cation transporter), member 4, [Score=250, Expect=1e-75]; ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=248, Expect=2e-74]} {Dmel: FBgn0019952, Orct, Organic cation transporter, [Score=272, Expect=3e-84]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=233, Expect=4e-69]} {Smed: dd_Smed_v6_10826_0_2, dd_Smed_v6_10826_0_2, [Score=211, Expect=3e-61]} {RNA1310_28487} {RNA815_52073}

Mlig455_003385 {REF} {Length: 2374} {Pfam: Major Facilitator Superfamily [PF07690.18, score=37.9]; Sugar (and other) transporter [PF00083.26, score=28.3]} {Human: ENSG00000197375, SLC22A5, solute carrier family 22 member 5, [Score=113, Expect=5e-26]; ENSG00000197208, SLC22A4, solute carrier family 22 member 4, [Score=111, Expect=2e-25]} {Mouse: ENSMUSG00000063652, Slc22a21, solute carrier family 22 (organic cation transporter), member 21, [Score=110, Expect=2e-25]; ENSMUSG00000018900, Slc22a5, solute carrier family 22 (organic cation transporter), member 5, [Score=107, Expect=2e-24]; ENSMUSG00000020334, Slc22a4, solute carrier family 22 (organic cation transporter), member 4, [Score=105, Expect=7e-24]} {Dmel: FBgn0086365, Orct2, Organic cation transporter 2, [Score=134, Expect=1e-33]} {Celegans: WBGene00003842, oct-1, Organic cation transporter 1, [Score=100, Expect=3e-22]} {RNA1310_28487} {RNA815_52073}
22. MligTC455_36727 2161 45.01 Mlig455_013407, Mlig455_013448

Neo: -

Age: logFC(26M/2M)=-0.438

Region-enriched R3: 1.447/0.00030

0.978 - - - - 0.978 -

Mlig455_013407 {REF} {Length: 3635} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1310_1688.1, RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611} {RNA1509_12599, RNA1509_16053, RNA1509_17696, RNA1509_23340, RNA1509_38884, RNA1509_44611, RNA815_14547}

Mlig455_013448 {REF} {Length: 3532} {RNA1509_17696} {RNA1310_1688.1} {RNA815_14547}
23. MligTC455_43485 1018 21.21 Mlig455_010044

Neo: -

Age: logFC(26M/2M)=1.232

Region-enriched R3: 2.130/0.00002

0.958 - - - 0.958 - - Mlig455_010044 {REF} {Length: 1690} {TRANSSPLICED} {Dmel: FBgn0040342, CG3706, [Score=130, Expect=3e-33]} {Celegans: WBGene00015469, C05D2.8, [Score=168, Expect=1e-47]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [RH, Score=229, Expect=1e-71]} {RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1310_12594.1, RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1509_13716, RNA1509_54778, RNA1509_9788, RNA815_5664}
24. MligTC455_12590 579 12.06 Mlig455_049883

Neo: -

Age: -

Region-enriched R3: 1.952/0.03324

SLC1A7 0.957 - - - - 0.957 - Mlig455_049883 {REF} {Length: 2234} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=406.4]} {Human: ENSG00000162383, SLC1A7, solute carrier family 1 member 7, [RH, Score=442, Expect=7e-150]; ENSG00000106688, SLC1A1, solute carrier family 1 member 1, [RH, Score=427, Expect=7e-145]} {Mouse: ENSMUSG00000024935, Slc1a1, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1, [RH, Score=446, Expect=5e-152]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=364, Expect=6e-121]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [Score=428, Expect=1e-145]} {Smed: dd_Smed_v6_1106_0_1, dd_Smed_v6_1106_0_1, [Score=449, Expect=2e-154]} {RNA1509_28921, RNA1509_5225} {RNA1310_19422.1, RNA1509_28921, RNA1509_5225} {RNA1509_28921, RNA1509_5225, RNA815_7338}
25. MligTC455_41415 3303 68.81 Mlig455_018644, Mlig455_018832

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.340/0.00000

ZCCHC9 0.956 - - - 0.956 - -

Mlig455_018644 {REF} {Length: 1852} {TRANSSPLICED} {Pfam: Zinc knuckle [PF00098.25, score=58.7]; Zinc knuckle [PF13696.8, score=41.1]} {Human: ENSG00000131732, ZCCHC9, zinc finger CCHC-type containing 9, [RH, Score=143, Expect=7e-41]} {Mouse: ENSMUSG00000021621, Zcchc9, zinc finger, CCHC domain containing 9, [RH, Score=144, Expect=3e-41]} {Celegans: WBGene00017210, F07E5.5, [RH, Score=111, Expect=2e-28]} {Smed: dd_Smed_v6_7172_0_1, dd_Smed_v6_7172_0_1, [RH, Score=128, Expect=2e-36]} {RNA1509_15308, RNA1509_21839} {RNA1310_28047.1, RNA1509_15308} {RNA1509_15308, RNA815_12618}

Mlig455_018832 {REF} {Length: 1231} {TRANSSPLICED} {Pfam: Zinc knuckle [PF00098.25, score=58.7]; Zinc knuckle [PF13696.8, score=41.1]} {Human: ENSG00000131732, ZCCHC9, zinc finger CCHC-type containing 9, [RH, Score=139, Expect=2e-39]} {Mouse: ENSMUSG00000021621, Zcchc9, zinc finger, CCHC domain containing 9, [RH, Score=140, Expect=5e-40]} {Celegans: WBGene00017210, F07E5.5, [RH, Score=111, Expect=2e-28]} {Smed: dd_Smed_v6_7172_0_1, dd_Smed_v6_7172_0_1, [RH, Score=128, Expect=2e-36]} {RNA1509_21839} {RNA1310_28047.1, RNA1509_21839} {RNA1509_21839, RNA815_12618}

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