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Results for MligTC455_38363

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_38363 2457 51.19 Mlig455_045500, Mlig455_065739

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.377

Region-enriched R3: 1.866/0.00436
Region-enriched R6: 1.855/0.01251
Region-enriched R5: 1.276/0.04355

Regeneration-upregulated TP: 3.564

Regeneration-enriched TP: 3.564

AADAC

Mlig455_045500 {REF} {Length: 2281} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.9]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=7e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=114, Expect=1e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.4, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=6e-28]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1, RNA1509_7598} {RNA1509_7598, RNA815_8354}

Mlig455_065739 {REF} {Length: 1875} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.8]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=8e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=113, Expect=2e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.0, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1} {RNA815_8354}

Cumulative graph for MligTC455_38363

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.645 5.844 0.45824 1.00000
RegionR2 0.149 5.844 0.79854 1.00000
RegionR3 1.866 5.844 0.00009 0.00436
RegionR4 1.13 5.844 0.04736 0.18594
RegionR5 1.276 5.844 0.00678 0.04355
RegionR6 1.855 5.844 0.00019 0.01251
RegionR7 -2.202 5.844 0.01098 0.18234
RegionR8 -4.718 5.844 0.00013 0.01062

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 0.756 5.844 0.46214 1.00000
RegenerationR2 0.21 5.844 0.72741 0.96484
RegenerationR3 0.277 5.844 0.64217 0.92587
RegenerationR4 0.718 5.844 0.24375 0.69184
RegenerationR5 0.146 5.844 0.80332 0.98918
RegenerationR6 0.28 5.844 0.63508 0.89017
RegenerationBL 0.755 5.844 0.36847 0.73673
RegenerationTP 3.564 5.844 0.00005 0.00716 Specific for TP: 3.564


Genes with expression patterns similar to MligTC455_38363

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_38363 2457 51.19 Mlig455_045500, Mlig455_065739

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=1.377

Region-enriched R3: 1.866/0.00436
Region-enriched R6: 1.855/0.01251
Region-enriched R5: 1.276/0.04355

Regeneration-upregulated TP: 3.564

Regeneration-enriched TP: 3.564

AADAC 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_045500 {REF} {Length: 2281} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.9]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=7e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=114, Expect=1e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.4, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=6e-28]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1, RNA1509_7598} {RNA1509_7598, RNA815_8354}

Mlig455_065739 {REF} {Length: 1875} {Pfam: alpha/beta hydrolase fold [PF07859.15, score=144.8]; Carboxylesterase family [PF00135.30, score=29.3]} {Human: ENSG00000114771, AADAC, arylacetamide deacetylase, [Score=109, Expect=8e-26]; ENSG00000261846, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]; ENSG00000197953, AADACL2, arylacetamide deacetylase like 2, [Score=107, Expect=5e-25]} {Mouse: ENSMUSG00000090527, Gm5538, predicted gene 5538, [Score=117, Expect=9e-29]; ENSMUSG00000095522, Gm8298, predicted gene 8298, [Score=113, Expect=2e-27]} {Dmel: FBgn0034491, Hsl, Hormone-sensitive lipase, [Score=82.0, Expect=2e-16]} {Celegans: WBGene00012810, nceh-1, Neutral Cholesterol Ester Hydrolase homolog, [Score=114, Expect=1e-27]} {Smed: dd_Smed_v6_4674_0_1, dd_Smed_v6_4674_0_1, [Score=101, Expect=1e-23]} {RNA1509_7598} {RNA1310_15560.1} {RNA815_8354}
2. MligTC455_53879 3408 71 Mlig455_056363

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.852/0.00001

CLCA1 4.25 0.740 0.816 - 0.979 0.781 0.934 Mlig455_056363 {REF} {Length: 3111} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=167.5]; von Willebrand factor type A domain [PF00092.30, score=46.2]; von Willebrand factor type A domain [PF13519.8, score=42.1]; von Willebrand factor type A domain [PF13768.8, score=37.2]; VWA domain containing CoxE-like protein [PF05762.16, score=23.6]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [RH, Score=265, Expect=9e-75]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [RH, Score=273, Expect=6e-78]} {Smed: dd_Smed_v6_968_0_1, dd_Smed_v6_968_0_1, [RH, Score=178, Expect=5e-46]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
3. MligTC455_47523 13702 285.47 Mlig455_066733

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.639

PRDX6 4.237 0.869 0.840 0.712 0.859 - 0.957 Mlig455_066733 {REF} {Length: 1378} {Pfam: AhpC/TSA family [PF00578.23, score=93.9]; Redoxin [PF08534.12, score=43.8]; C-terminal domain of 1-Cys peroxiredoxin [PF10417.11, score=35.1]} {Human: ENSG00000117592, PRDX6, peroxiredoxin 6, [RH, Score=270, Expect=5e-92]} {Mouse: ENSMUSG00000026701, Prdx6, peroxiredoxin 6, [RH, Score=262, Expect=5e-89]; ENSMUSG00000050114, Prdx6b, peroxiredoxin 6B, [RH, Score=251, Expect=2e-84]} {Dmel: FBgn0031479, Prx6005, Peroxiredoxin 6005, [RH, Score=253, Expect=1e-85]} {Celegans: WBGene00021401, prdx-6, PeRoxireDoXin, [RH, Score=222, Expect=1e-73]} {Smed: dd_Smed_v6_3299_0_1, dd_Smed_v6_3299_0_1, [RH, Score=226, Expect=2e-75]} {RNA1509_12645, RNA1509_5350, RNA1509_932} {RNA1310_32794.1, RNA1509_12645, RNA1509_5350, RNA1509_932} {RNA1509_12645, RNA1509_5350, RNA1509_932, RNA815_15092}
4. MligTC455_47129 1019 21.23 Mlig455_054855

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.966/0.00119
Region-enriched R5: 1.198/0.04937

4.153 - 0.764 0.813 0.950 0.749 0.877 Mlig455_054855 {REF} {Length: 2253} {Pfam: Syntaxin 6, N-terminal [PF09177.13, score=37.3]} {RNA1509_18917, RNA1509_23730} {RNA1310_20266, RNA1509_18917, RNA1509_23730} {RNA1509_18917, RNA1509_23730, RNA815_12077}
5. MligTC455_52971 2407 50.15 Mlig455_050623

Neo: -

Age: logFC(26M/2M)=-0.616

Region-enriched R4: 1.402/0.00014
Region-enriched R3: 1.372/0.00001

3.518 0.764 0.832 - 0.975 - 0.947 Mlig455_050623 {REF} {Length: 1302} {RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1310_29014, RNA1509_18850, RNA1509_3980, RNA1509_4657} {RNA1509_18850, RNA1509_3980, RNA1509_4657, RNA815_8071.2}
6. MligTC455_44838 1113 23.18 Mlig455_035218, Mlig455_035266

Neo: -

Age: -

MAN2B1 3.46 - 0.780 0.781 0.971 - 0.928

Mlig455_035218 {REF} {Length: 3151} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=269.2]; Alpha mannosidase middle domain [PF09261.13, score=64.9]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=44.0]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.3]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=630, Expect=0.0]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=607, Expect=0.0]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=636, Expect=0.0]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [RH, Score=502, Expect=9e-163]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=674, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1, RNA1509_7785} {RNA1509_7785, RNA815_7617}

Mlig455_035266 {REF} {Length: 2979} {Pfam: Glycosyl hydrolases family 38 N-terminal domain [PF01074.24, score=189.2]; Alpha mannosidase middle domain [PF09261.13, score=64.8]; Glycosyl hydrolases family 38 C-terminal domain [PF07748.15, score=45.6]; Glycosyl hydrolases family 38 C-terminal beta sandwich domain [PF17677.3, score=32.4]} {Human: ENSG00000104774, MAN2B1, mannosidase alpha class 2B member 1, [Score=531, Expect=1e-173]} {Mouse: ENSMUSG00000005142, Man2b1, mannosidase 2, alpha B1, [Score=501, Expect=6e-162]} {Dmel: FBgn0027611, LManII, Lysosomal alpha-mannosidase II, [Score=538, Expect=2e-175]} {Celegans: WBGene00018877, aman-1, Alpha-mannosidase, [Score=428, Expect=4e-135]} {Smed: dd_Smed_v6_1942_0_1, dd_Smed_v6_1942_0_1, [Score=566, Expect=0.0]} {RNA1509_7785} {RNA1310_4896.1} {RNA815_7617}
7. MligTC455_53878 8131 169.39 Mlig455_056351

Neo: -

Age: logFC(26M/2M)=0.398

Region-enriched R3: 1.950/0.00000
Region-enriched R5: 1.089/0.01986

CLCA1 3.445 - 0.794 - 0.882 0.811 0.958 Mlig455_056351 {REF} {Length: 4429} {Pfam: Calcium-activated chloride channel N terminal [PF08434.13, score=166.8]; von Willebrand factor type A domain [PF00092.30, score=30.4]; von Willebrand factor type A domain [PF13519.8, score=27.0]; von Willebrand factor type A domain [PF13768.8, score=23.5]} {Human: ENSG00000016490, CLCA1, chloride channel accessory 1, [Score=166, Expect=2e-41]} {Mouse: ENSMUSG00000028255, Clca1, chloride channel accessory 1, [Score=165, Expect=5e-41]} {Celegans: WBGene00018026, F35A5.4, [Score=58.2, Expect=3e-08]} {RNA1509_656} {RNA1310_5461.1} {RNA815_1665}
8. MligTC455_22673 360 7.5 Mlig455_000445, Mlig455_000506

Neo: -

Age: -

Region-enriched R6: 2.650/0.00606
Region-enriched R3: 2.407/0.00814

3.329 0.700 - 0.849 - 0.827 0.953

Mlig455_000445 {REF} {Length: 3282} {Pfam: Trehalose receptor [PF06151.15, score=36.5]; 7tm Chemosensory receptor [PF08395.14, score=32.2]; 7tm Odorant receptor [PF02949.22, score=21.9]} {RNA1509_29330} {RNA1310_14782} {RNA815_2784}

Mlig455_000506 {REF} {Length: 3189} {Pfam: Trehalose receptor [PF06151.15, score=37.9]; 7tm Chemosensory receptor [PF08395.14, score=31.4]; 7tm Odorant receptor [PF02949.22, score=23.2]} {RNA1509_29330} {RNA1310_14782} {RNA815_2784}
9. MligTC455_30094 4128 86.01 Mlig455_015674, Mlig455_062483

Neo: -

Age: Down-Down-Up

3.288 0.719 - - 0.966 0.768 0.835

Mlig455_015674 {REF} {Length: 3057} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=126.7]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [Score=421, Expect=4e-138]} {RNA1509_3901} {RNA1310_1179.2} {RNA815_296.2}

Mlig455_062483 {REF} {Length: 3106} {Pfam: Domain of unknown function (DUF5054) [PF16477.7, score=125.5]} {Smed: dd_Smed_v6_540_0_1, dd_Smed_v6_540_0_1, [RH, Score=486, Expect=1e-161]} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1310_1179.1, RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971} {RNA1509_2252, RNA1509_33702, RNA1509_3901, RNA1509_40155, RNA1509_41231, RNA1509_4971, RNA815_296.2}
10. MligTC455_32555 3333 69.45 Mlig455_023825

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.526

Region-enriched R3: 1.882/0.00000
Region-enriched R4: 1.126/0.03622

PRSS12 3.198 - 0.720 - 0.975 0.754 0.749 Mlig455_023825 {REF} {Length: 4714} {Pfam: Trypsin [PF00089.28, score=216.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=95.2]; Low-density lipoprotein receptor domain class A [PF00057.20, score=94.1]; Scavenger receptor cysteine-rich domain [PF15494.8, score=25.1]; Trypsin-like peptidase domain [PF13365.8, score=20.3]; Nematode trypsin-6-like family [PF03761.17, score=18.5]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=220, Expect=4e-60]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=212, Expect=3e-58]} {Dmel: FBgn0023479, teq, Tequila, [Score=286, Expect=1e-81]} {Celegans: WBGene00006620, svh-1, HGF/MSP/plasminogen-like protein, [RH, Score=191, Expect=2e-50]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=489, Expect=7e-158]} {RNA1509_337} {RNA1310_1502.2} {RNA815_422}
11. MligTC455_43133 2633 54.86 Mlig455_033697, Mlig455_050134

Neo: -

Age: -

Region-enriched R3: 2.075/0.00231
Region-enriched R4: 1.915/0.02367

ENPP5 2.752 - 0.779 - 0.998 - 0.975

Mlig455_033697 {REF} {Length: 1895} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=202.8]; Sulfatase [PF00884.25, score=38.8]; Protein of unknown function (DUF1501) [PF07394.14, score=23.7]; Metalloenzyme superfamily [PF01676.20, score=18.8]} {Human: ENSG00000112796, ENPP5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative), [Score=207, Expect=8e-60]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [Score=198, Expect=1e-56]} {Mouse: ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [Score=209, Expect=1e-60]} {Celegans: WBGene00015283, C01B10.9, [RH, Score=160, Expect=1e-42]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [Score=180, Expect=5e-50]} {RNA1509_8220} {RNA1310_19894.1} {RNA815_8419}

Mlig455_050134 {REF} {Length: 1895} {Pfam: Type I phosphodiesterase / nucleotide pyrophosphatase [PF01663.24, score=201.5]; Sulfatase [PF00884.25, score=38.5]; Protein of unknown function (DUF1501) [PF07394.14, score=21.0]; Metalloenzyme superfamily [PF01676.20, score=18.3]} {Human: ENSG00000112796, ENPP5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative), [Score=206, Expect=2e-59]; ENSG00000001561, ENPP4, ectonucleotide pyrophosphatase/phosphodiesterase 4, [Score=197, Expect=2e-56]} {Mouse: ENSMUSG00000023960, Enpp5, ectonucleotide pyrophosphatase/phosphodiesterase 5, [Score=208, Expect=2e-60]} {Celegans: WBGene00015283, C01B10.9, [RH, Score=160, Expect=2e-42]} {Smed: dd_Smed_v6_9016_0_1, dd_Smed_v6_9016_0_1, [Score=179, Expect=1e-49]} {RNA1509_8220} {RNA1310_19894.1} {RNA815_8419}
12. MligTC455_27625 5733 119.44 Mlig455_018765

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.886/0.00051

MATN2 2.654 - 0.768 - 0.934 - 0.952 Mlig455_018765 {REF} {Length: 2544} {Pfam: von Willebrand factor type A domain [PF00092.30, score=235.9]; von Willebrand factor type A domain [PF13519.8, score=103.0]; von Willebrand factor type A domain [PF13768.8, score=54.3]; VWA domain containing CoxE-like protein [PF05762.16, score=36.8]; Protein of unknown function (DUF1194) [PF06707.13, score=35.1]} {Human: ENSG00000132561, MATN2, matrilin 2, [Score=97.1, Expect=3e-20]} {Mouse: ENSMUSG00000040533, Matn1, matrilin 1, cartilage matrix protein, [Score=105, Expect=1e-23]} {Celegans: WBGene00003482, mua-3, Transmembrane cell adhesion receptor mua-3, [Score=82.0, Expect=8e-16]} {Smed: dd_Smed_v6_2674_0_1, dd_Smed_v6_2674_0_1, [Score=92.0, Expect=3e-19]} {RNA1509_3165} {RNA1310_8996, RNA1509_3165} {RNA1509_3165, RNA815_2915.1}
13. MligTC455_20619 2288 47.67 Mlig455_055574

Neo: -

Age: Down-Down-Up

Region-enriched R3: 1.591/0.00258
Region-enriched R4: 1.303/0.03358

SLC24A5 2.64 - - - 0.960 0.743 0.937 Mlig455_055574 {REF} {Length: 3527} {Pfam: Sodium/calcium exchanger protein [PF01699.26, score=180.5]} {Human: ENSG00000188467, SLC24A5, solute carrier family 24 member 5, [RH, Score=378, Expect=2e-125]} {Mouse: ENSMUSG00000035183, Slc24a5, solute carrier family 24, member 5, [RH, Score=378, Expect=1e-125]} {Dmel: FBgn0265767, zyd, zydeco, [Score=359, Expect=2e-118]} {Celegans: WBGene00003569, ncx-4, Na/Ca eXchangers, [Score=304, Expect=4e-96]} {Smed: dd_Smed_v6_7121_0_1, dd_Smed_v6_7121_0_1, [RH, Score=469, Expect=1e-161]} {RNA1509_4708} {RNA1310_7971.1} {RNA815_7327}
14. MligTC455_19590 915 19.06 Mlig455_051962

Neo: -

Age: -

2.639 0.737 - - 0.943 - 0.959 Mlig455_051962 {REF} {Length: 852} {RNA1509_20360} {RNA1310_37068, RNA1509_20360} {RNA1509_20360, RNA815_23648}
15. MligTC455_11650 1098 22.87 Mlig455_007133

Neo: -

Age: logFC(26M/2M)=1.455

Region-enriched R4: 2.055/0.00000
Region-enriched R3: 1.617/0.00001
Region-enriched R5: 1.032/0.00532

2.621 - - - 0.973 0.719 0.929 Mlig455_007133 {REF} {Length: 1372} {Pfam: Tyrosine phosphatase family [PF13350.8, score=133.9]; Tyrosine phosphatase family [PF03162.15, score=32.8]} {Smed: dd_Smed_v6_6110_0_1, dd_Smed_v6_6110_0_1, [RH, Score=96.3, Expect=2e-22]} {RNA1509_24412} {RNA1310_29199} {RNA815_14210.1}
16. MligTC455_45571 861 17.95 Mlig455_014290

Neo: -

Age: Down-Down-Up

Region-enriched R4: 3.155/0.00000
Region-enriched R3: 2.172/0.00010
Region-enriched R5: 2.084/0.00005
Region-enriched R6: 1.840/0.00926

Regeneration-upregulated BL: 3.314

Regeneration-enriched BL: 3.314

CRYL1 2.603 - 0.782 - 0.979 - 0.842 Mlig455_014290 {REF} {Length: 1393} {Pfam: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain [PF02737.20, score=151.9]; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain [PF00725.24, score=33.8]} {Human: ENSG00000165475, CRYL1, crystallin lambda 1, [RH, Score=263, Expect=2e-86]} {Mouse: ENSMUSG00000021947, Cryl1, crystallin, lambda 1, [RH, Score=250, Expect=2e-81]} {Dmel: FBgn0030737, CG9914, [RH, Score=276, Expect=1e-91]} {Celegans: WBGene00022130, Y71F9B.9, [RH, Score=238, Expect=8e-77]} {Smed: dd_Smed_v6_1696_0_1, dd_Smed_v6_1696_0_1, [RH, Score=170, Expect=9e-51]} {RNA1509_34725} {RNA1310_23652, RNA1509_34725} {RNA1509_34725, RNA815_8421.1}
17. MligTC455_53366 2231 46.48 Mlig455_004303

Neo: -

Age: -

Region-enriched R3: 1.061/0.04127

DHCR24 2.593 - 0.758 - 0.957 - 0.878 Mlig455_004303 {REF} {Length: 2028} {Human: ENSG00000116133, DHCR24, 24-dehydrocholesterol reductase, [Score=124, Expect=2e-33]} {Mouse: ENSMUSG00000034926, Dhcr24, 24-dehydrocholesterol reductase, [Score=124, Expect=2e-33]} {Celegans: WBGene00012407, Y7A5A.1, [Score=239, Expect=5e-77]} {Smed: dd_Smed_v6_21866_0_1, dd_Smed_v6_21866_0_1, [Score=203, Expect=2e-63]} {RNA1509_46378} {RNA1310_2661.1} {RNA815_713.1}
18. MligTC455_28793 5084 105.92 Mlig455_060183

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.494

Region-enriched R3: 1.548/0.02653

MUC5B 2.588 - 0.828 - 0.961 - 0.799 Mlig455_060183 {REF} {Length: 13150} {Pfam: Mucin-2 protein WxxW repeating region [PF13330.8, score=446.8]; von Willebrand factor type D domain [PF00094.27, score=233.8]; C8 domain [PF08742.13, score=102.9]; Trypsin Inhibitor like cysteine rich domain [PF01826.19, score=57.0]; F5/8 type C domain [PF00754.27, score=50.9]} {Human: ENSG00000117983, MUC5B, mucin 5B, oligomeric mucus/gel-forming, [RH, Score=593, Expect=7e-169]; ENSG00000215182, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]; ENSG00000283158, MUC5AC, mucin 5AC, oligomeric mucus/gel-forming, [RH, Score=590, Expect=7e-168]} {Mouse: ENSMUSG00000066108, Muc5b, mucin 5, subtype B, tracheobronchial, [RH, Score=545, Expect=1e-154]} {Dmel: FBgn0029167, Hml, Hemolectin, [RH, Score=512, Expect=6e-145]} {Celegans: WBGene00006820, unc-89, Muscle M-line assembly protein unc-89, [Score=68.6, Expect=2e-10]} {Smed: dd_Smed_v6_17988_0_1, dd_Smed_v6_17988_0_1, [Score=439, Expect=1e-123]} {RNA1509_4763} {RNA1310_151.1} {RNA815_89.1}
19. MligTC455_53367 4909 102.27 Mlig455_004255, Mlig455_004324

Neo: -

Age: logFC(26M/2M)=0.436

DHCR24 2.582 - 0.779 - 0.957 - 0.846

Mlig455_004255 {REF} {Length: 2167} {Pfam: FAD binding domain [PF01565.25, score=44.6]} {Human: ENSG00000116133, DHCR24, 24-dehydrocholesterol reductase, [Score=381, Expect=2e-126]} {Mouse: ENSMUSG00000034926, Dhcr24, 24-dehydrocholesterol reductase, [Score=382, Expect=5e-127]} {Celegans: WBGene00012407, Y7A5A.1, [RH, Score=743, Expect=0.0]} {Smed: dd_Smed_v6_21866_0_1, dd_Smed_v6_21866_0_1, [RH, Score=668, Expect=0.0]} {RNA1509_4007} {RNA1310_2661.1} {RNA815_713.1}

Mlig455_004324 {REF} {Length: 2166} {Pfam: FAD binding domain [PF01565.25, score=44.6]} {Human: ENSG00000116133, DHCR24, 24-dehydrocholesterol reductase, [Score=381, Expect=1e-126]} {Mouse: ENSMUSG00000034926, Dhcr24, 24-dehydrocholesterol reductase, [Score=382, Expect=3e-127]} {Celegans: WBGene00012407, Y7A5A.1, [RH, Score=745, Expect=0.0]} {Smed: dd_Smed_v6_21866_0_1, dd_Smed_v6_21866_0_1, [RH, Score=669, Expect=0.0]} {RNA1509_2731, RNA1509_4007, RNA1509_6704} {RNA1310_2661.1, RNA1509_2731, RNA1509_4007, RNA1509_6704} {RNA1509_2731, RNA1509_4007, RNA1509_6704, RNA815_713.1}
20. MligTC455_44136 8031 167.32 Mlig455_024689, Mlig455_024714

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=0.859

Region-enriched R4: 1.310/0.01340
Region-enriched R3: 1.215/0.02536

FADS2 2.578 - 0.796 - - 0.832 0.950

Mlig455_024689 {REF} {Length: 3861} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=116.9]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=429, Expect=6e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=426, Expect=8e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=446, Expect=7e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=3e-109]} {RNA1509_1792, RNA1509_9754} {RNA1310_4526, RNA1509_1792, RNA1509_9754} {RNA1509_1792, RNA1509_9754, RNA815_4497}

Mlig455_024714 {REF} {Length: 5232} {TRANSSPLICED} {Pfam: Fatty acid desaturase [PF00487.26, score=117.3]; Cytochrome b5-like Heme/Steroid binding domain [PF00173.30, score=75.0]} {Human: ENSG00000134824, FADS2, fatty acid desaturase 2, [RH, Score=430, Expect=3e-148]; ENSG00000149485, FADS1, fatty acid desaturase 1, [RH, Score=427, Expect=2e-146]} {Mouse: ENSMUSG00000024665, Fads2, fatty acid desaturase 2, [RH, Score=447, Expect=3e-155]} {Dmel: FBgn0029854, CG3566, [Score=56.2, Expect=7e-10]} {Celegans: WBGene00001395, fat-3, Delta(6)-fatty-acid desaturase fat-3, [Score=130, Expect=2e-33]} {Smed: dd_Smed_v6_10869_0_1, dd_Smed_v6_10869_0_1, [Score=328, Expect=6e-109]} {RNA1509_9754} {RNA1310_4526} {RNA815_4497}
21. MligTC455_37113 9210 191.88 Mlig455_020693

Neo: -

Age: -

Region-enriched R3: 1.525/0.00009

LGMN 2.574 - - 0.883 - 0.732 0.959 Mlig455_020693 {REF} {Length: 3890} {Pfam: Peptidase C13 family [PF01650.20, score=361.0]} {Human: ENSG00000100600, LGMN, legumain, [RH, Score=382, Expect=2e-129]} {Mouse: ENSMUSG00000021190, Lgmn, legumain, [RH, Score=388, Expect=4e-132]} {Dmel: FBgn0023545, PIG-K, Phosphatidylinositol glycan anchor biosynthesis class K, [Score=127, Expect=1e-32]} {Celegans: WBGene00012144, T28H10.3, [RH, Score=327, Expect=7e-108]} {Smed: dd_Smed_v6_6456_0_1, dd_Smed_v6_6456_0_1, [Score=105, Expect=3e-25]} {RNA1509_312} {RNA1310_13933, RNA1509_312} {RNA1509_312, RNA815_6243.1}
22. MligTC455_37239 1846 38.46 Mlig455_060082

Neo: -

Age: -

Region-enriched R3: 1.562/0.04763
Region-enriched R5: 1.292/0.04648

PANK4 2.56 - 0.724 0.886 - - 0.950 Mlig455_060082 {REF} {Length: 1532} {Pfam: Fumble [PF03630.16, score=120.5]} {Human: ENSG00000273494, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]; ENSG00000157881, PANK4, pantothenate kinase 4, [Score=106, Expect=2e-24]} {Mouse: ENSMUSG00000029056, Pank4, pantothenate kinase 4, [Score=97.4, Expect=1e-21]} {Dmel: FBgn0011205, fbl, fumble, [Score=66.2, Expect=7e-12]} {Smed: dd_Smed_v6_2075_0_1, dd_Smed_v6_2075_0_1, [Score=170, Expect=1e-49]} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1310_20224, RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233} {RNA1509_11609, RNA1509_12632, RNA1509_47615, RNA1509_9233, RNA815_7673}
23. MligTC455_18723 1597 33.27 Mlig455_004384

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.781

Region-enriched R3: 2.164/0.00079
Region-enriched R4: 1.576/0.04930
Region-enriched R5: 1.329/0.03977

SLC3A1 2.555 - 0.793 0.811 - - 0.951 Mlig455_004384 {REF} {Length: 2040} {Pfam: Alpha amylase, catalytic domain [PF00128.26, score=310.6]} {Human: ENSG00000138079, SLC3A1, solute carrier family 3 member 1, [RH, Score=371, Expect=2e-119]} {Mouse: ENSMUSG00000024131, Slc3a1, solute carrier family 3, member 1, [RH, Score=372, Expect=4e-120]} {Dmel: FBgn0002570, Mal-A1, Maltase A1, [RH, Score=384, Expect=2e-126]} {Celegans: WBGene00000224, atgp-1, Amino acid Transporter GlycoProtein subunit, [RH, Score=146, Expect=3e-37]} {Smed: dd_Smed_v6_2113_0_1, dd_Smed_v6_2113_0_1, [Score=67.8, Expect=8e-12]} {RNA1509_19345} {RNA1310_12682.1} {RNA815_15968}
24. MligTC455_36240 5999 124.98 Mlig455_043113

Neo: -

Age: logFC(26M/2M)=0.402

EPHX4 2.517 0.739 0.825 - - - 0.953 Mlig455_043113 {REF} {Length: 2152} {Pfam: alpha/beta hydrolase fold [PF00561.22, score=86.1]; Alpha/beta hydrolase family [PF12697.9, score=72.2]; Serine aminopeptidase, S33 [PF12146.10, score=55.9]; Ndr family [PF03096.16, score=20.5]} {Human: ENSG00000172031, EPHX4, epoxide hydrolase 4, [RH, Score=248, Expect=1e-78]} {Mouse: ENSMUSG00000033805, Ephx4, epoxide hydrolase 4, [RH, Score=237, Expect=1e-74]} {Dmel: FBgn0035951, CG5068, [Score=49.7, Expect=3e-06]} {Celegans: WBGene00019329, ceeh-1, Epoxide hydrolase 1, [RH, Score=228, Expect=1e-70]} {Smed: dd_Smed_v6_2011_0_1, dd_Smed_v6_2011_0_1, [RH, Score=252, Expect=8e-81]} {RNA1509_19687, RNA1509_20879, RNA1509_7823} {RNA1310_15717.1, RNA1509_19687, RNA1509_20879} {RNA1509_19687, RNA1509_20879, RNA815_5437.1}
25. MligTC455_50561 1589 33.11 Mlig455_055225

Neo: -

Age: -

Region-enriched R5: 1.845/0.00000
Region-enriched R6: 1.416/0.01329

CERS2 2.508 - - 0.810 0.972 - 0.726 Mlig455_055225 {REF} {Length: 2717} {Pfam: TLC domain [PF03798.18, score=138.6]} {Human: ENSG00000143418, CERS2, ceramide synthase 2, [Score=230, Expect=7e-72]} {Mouse: ENSMUSG00000015714, Cers2, ceramide synthase 2, [Score=233, Expect=2e-73]} {Dmel: FBgn0040918, schlank, [RH, Score=228, Expect=4e-71]} {Celegans: WBGene00002043, hyl-1, Ceramide synthase hyl-1, [Score=158, Expect=1e-45]} {Smed: dd_Smed_v6_4223_0_1, dd_Smed_v6_4223_0_1, [Score=231, Expect=5e-73]} {RNA1509_22029, RNA1509_5457} {RNA1310_7363.1, RNA1509_22029} {RNA1509_22029, RNA815_2329.1}
26. MligTC455_32901 454 9.47 Mlig455_067826

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.415

Region-enriched R3: 2.470/0.00379

CA7 2.488 - 0.768 0.757 - - 0.963 Mlig455_067826 {REF} {Length: 1496} {Pfam: Eukaryotic-type carbonic anhydrase [PF00194.23, score=243.6]} {Human: ENSG00000168748, CA7, carbonic anhydrase 7, [RH, Score=207, Expect=8e-66]; ENSG00000133742, CA1, carbonic anhydrase 1, [RH, Score=197, Expect=1e-61]} {Mouse: ENSMUSG00000027562, Car2, carbonic anhydrase 2, [RH, Score=204, Expect=1e-64]} {Dmel: FBgn0027844, CAH1, Carbonic anhydrase 1, [Score=192, Expect=2e-60]} {Celegans: WBGene00000281, cah-3, Putative carbonic anhydrase 3, [RH, Score=137, Expect=2e-39]} {Smed: dd_Smed_v6_5784_0_1, dd_Smed_v6_5784_0_1, [Score=187, Expect=4e-58]} {RNA1509_23444, RNA1509_34487} {RNA1310_23047.1, RNA1509_23444, RNA1509_34487} {RNA1509_23444, RNA1509_34487, RNA815_11571.2}
27. MligTC455_44102 5169 107.69 Mlig455_011991

Neo: -

Age: logFC(26M/2M)=0.278

Region-enriched R3: 1.948/0.00360
Region-enriched R4: 1.688/0.02863

HPGDS 2.448 0.783 - 0.705 - - 0.960 Mlig455_011991 {REF} {Length: 1746} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=43.5]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=42.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=22.6]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=20.1]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=19.1]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=67.8, Expect=2e-13]} {Mouse: ENSMUSG00000025934, Gsta3, glutathione S-transferase, alpha 3, [Score=62.4, Expect=1e-11]; ENSMUSG00000032348, Gsta4, glutathione S-transferase, alpha 4, [Score=60.5, Expect=6e-11]; ENSMUSG00000029919, Hpgds, hematopoietic prostaglandin D synthase, [Score=60.5, Expect=5e-11]} {Celegans: WBGene00001756, gst-8, Probable glutathione S-transferase 8, [Score=84.0, Expect=5e-20]} {Smed: dd_Smed_v6_20_0_1, dd_Smed_v6_20_0_1, [Score=115, Expect=4e-32]} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1310_14959.1, RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359} {RNA1509_2160, RNA1509_26612, RNA1509_28516, RNA1509_5091, RNA1509_6359, RNA815_7403}
28. MligTC455_48232 9746 203.05 Mlig455_003482

Neo: -

Age: logFC(26M/2M)=0.354

Region-enriched R3: 1.696/0.00172
Region-enriched R4: 1.464/0.01190

GSTP1 2.44 - - 0.771 - 0.716 0.953 Mlig455_003482 {REF} {Length: 9216} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=55.9]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=40.4]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=28.8]; Glutathione S-transferase, N-terminal domain [PF13417.8, score=26.9]; Glutathione S-transferase, N-terminal domain [PF13409.8, score=21.9]; Glutathione S-transferase, C-terminal domain [PF13410.8, score=20.9]} {Human: ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=117, Expect=3e-32]} {Mouse: ENSMUSG00000097830, Gstp1, glutathione S-transferase, pi 1, [Score=125, Expect=1e-35]; ENSMUSG00000060803, Gstp1, glutathione S-transferase, pi 1, [Score=125, Expect=1e-35]; ENSMUSG00000097808, Gstp2, glutathione S-transferase, pi 2, [Score=123, Expect=1e-34]; ENSMUSG00000038155, Gstp2, glutathione S-transferase, pi 2, [Score=123, Expect=1e-34]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=85.9, Expect=4e-20]} {Celegans: WBGene00001771, gst-23, Glutathione S-Transferase, [Score=116, Expect=2e-32]} {Smed: dd_Smed_v6_1206_0_1, dd_Smed_v6_1206_0_1, [Score=82.8, Expect=1e-19]} {RNA1509_25858} {RNA1310_22609} {RNA815_21250}
29. MligTC455_43485 1018 21.21 Mlig455_010044

Neo: -

Age: logFC(26M/2M)=1.232

Region-enriched R3: 2.130/0.00002

1.875 - 0.904 - 0.971 - - Mlig455_010044 {REF} {Length: 1690} {TRANSSPLICED} {Dmel: FBgn0040342, CG3706, [Score=130, Expect=3e-33]} {Celegans: WBGene00015469, C05D2.8, [Score=168, Expect=1e-47]} {Smed: dd_Smed_v6_8821_0_1, dd_Smed_v6_8821_0_1, [RH, Score=229, Expect=1e-71]} {RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1310_12594.1, RNA1509_13716, RNA1509_54778, RNA1509_9788} {RNA1509_13716, RNA1509_54778, RNA1509_9788, RNA815_5664}
30. MligTC455_39549 1949 40.61 Mlig455_004602

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.654

Region-enriched R5: 2.577/0.00276
Region-enriched R4: 2.372/0.03782

1.86 - - - 0.957 - 0.903 Mlig455_004602 {REF} {Length: 3069} {Pfam: Universal stress protein family [PF00582.28, score=98.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=106, Expect=1e-29]} {RNA1509_6489} {RNA1310_12949, RNA1509_6489} {RNA1509_6489, RNA815_11224}
31. MligTC455_45981 1146 23.87 Mlig455_050420

Neo: -

Age: logFC(26M/2M)=0.478

CYP2J2 1.855 - - - 0.977 - 0.878 Mlig455_050420 {REF} {Length: 2403} {Pfam: Cytochrome P450 [PF00067.24, score=310.0]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=234, Expect=2e-70]; ENSG00000155016, CYP2U1, cytochrome P450 family 2 subfamily U member 1, [Score=231, Expect=8e-69]} {Mouse: ENSMUSG00000052914, Cyp2j6, cytochrome P450, family 2, subfamily j, polypeptide 6, [Score=237, Expect=6e-72]; ENSMUSG00000081225, Cyp2j12, cytochrome P450, family 2, subfamily j, polypeptide 12, [Score=236, Expect=1e-71]; ENSMUSG00000052520, Cyp2j5, cytochrome P450, family 2, subfamily j, polypeptide 5, [Score=234, Expect=9e-71]; ENSMUSG00000066704, Cyp2b19, cytochrome P450, family 2, subfamily b, polypeptide 19, [Score=233, Expect=4e-70]; ENSMUSG00000027983, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=231, Expect=2e-69]; ENSMUSG00000116063, Cyp2u1, cytochrome P450, family 2, subfamily u, polypeptide 1, [Score=231, Expect=2e-69]; ENSMUSG00000030670, Cyp2r1, cytochrome P450, family 2, subfamily r, polypeptide 1, [Score=226, Expect=1e-67]} {Dmel: FBgn0010383, Cyp18a1, Cytochrome P450-18a1, [Score=228, Expect=3e-68]} {Celegans: WBGene00016768, cyp-33E1, CYtochrome P450 family, [RH, Score=228, Expect=1e-68]} {Smed: dd_Smed_v6_3919_0_3, dd_Smed_v6_3919_0_3, [Score=264, Expect=2e-82]} {RNA1509_22870} {RNA1310_10897, RNA1509_22870} {RNA1509_22870, RNA815_4157.1}
32. MligTC455_48360 594 12.37 Mlig455_034363

Neo: -

Age: -

Region-enriched R3: 2.361/0.00279
Region-enriched R4: 2.128/0.02443

1.835 - 0.865 - - - 0.970 Mlig455_034363 {REF} {Length: 3889} {Pfam: Death domain [PF00531.24, score=30.1]} {Celegans: WBGene00002041, hum-8, Heavy chain, Unconventional Myosin, [Score=50.4, Expect=6e-06]} {Smed: dd_Smed_v6_13807_0_1, dd_Smed_v6_13807_0_1, [Score=105, Expect=3e-23]} {RNA1509_29690, RNA1509_59375} {RNA1310_5206.1, RNA1509_59375} {RNA1509_59375, RNA815_3494}
33. MligTC455_19571 263 5.49 Mlig455_003635

Neo: -

Age: -

CRYZ 1.819 - - 0.962 - - 0.857 Mlig455_003635 {REF} {Length: 1497} {TRANSSPLICED} {Pfam: Zinc-binding dehydrogenase [PF00107.28, score=65.2]; Zinc-binding dehydrogenase [PF13602.8, score=47.1]; Alcohol dehydrogenase GroES-like domain [PF08240.14, score=35.1]} {Human: ENSG00000116791, CRYZ, crystallin zeta, [RH, Score=281, Expect=4e-93]} {Mouse: ENSMUSG00000028199, Cryz, crystallin, zeta, [RH, Score=286, Expect=4e-95]} {Dmel: FBgn0033883, CG16935, [RH, Score=70.9, Expect=2e-13]} {Celegans: WBGene00009554, F39B2.3, [RH, Score=223, Expect=1e-70]} {Smed: dd_Smed_v6_2717_0_1, dd_Smed_v6_2717_0_1, [RH, Score=254, Expect=5e-83]} {RNA1509_24531} {RNA1310_28792.1} {RNA815_12373.1}
34. MligTC455_49294 2730 56.88 Mlig455_030635

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.451

Region-enriched R3: 1.379/0.00585

SERPINB1 1.814 - - - 0.958 - 0.856 Mlig455_030635 {REF} {Length: 2337} {TRANSSPLICED} {Pfam: Serpin (serine protease inhibitor) [PF00079.22, score=369.3]} {Human: ENSG00000021355, SERPINB1, serpin family B member 1, [RH, Score=247, Expect=2e-78]; ENSG00000206072, SERPINB11, serpin family B member 11 (gene/pseudogene), [RH, Score=237, Expect=2e-74]} {Mouse: ENSMUSG00000052180, Serpinb6c, serine (or cysteine) peptidase inhibitor, clade B, member 6c, [RH, Score=255, Expect=1e-81]; ENSMUSG00000044734, Serpinb1a, serine (or cysteine) peptidase inhibitor, clade B, member 1a, [RH, Score=254, Expect=2e-81]; ENSMUSG00000047889, Serpinb6d, serine (or cysteine) peptidase inhibitor, clade B, member 6d, [RH, Score=246, Expect=4e-78]} {Dmel: FBgn0028983, Spn55B, Serpin 55B, [RH, Score=197, Expect=3e-59]} {Celegans: WBGene00005648, srp-7, SeRPin; Serine or cysteine protease inhibitor, [RH, Score=187, Expect=1e-55]} {Smed: dd_Smed_v6_3824_0_1, dd_Smed_v6_3824_0_1, [RH, Score=240, Expect=3e-76]} {RNA1509_12753, RNA1509_14486, RNA1509_1486, RNA1509_8328} {RNA1310_18852, RNA1509_12753, RNA1509_14486, RNA1509_1486, RNA1509_8328} {RNA1509_12753, RNA1509_14486, RNA1509_1486, RNA1509_8328, RNA815_2173}
35. MligTC455_36733 420 8.75 Mlig455_048506

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.830/0.00236
Region-enriched R3: 1.486/0.01919
Region-enriched R5: 1.349/0.01221

RAC2 1.8 - - - - 0.835 0.965 Mlig455_048506 {REF} {Length: 1750} {Pfam: Ras family [PF00071.24, score=184.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=79.1]; ADP-ribosylation factor family [PF00025.23, score=31.9]} {Human: ENSG00000128340, RAC2, Rac family small GTPase 2, [RH, Score=344, Expect=3e-122]; ENSG00000169750, RAC3, Rac family small GTPase 3, [RH, Score=329, Expect=4e-116]} {Mouse: ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [RH, Score=341, Expect=3e-121]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [RH, Score=329, Expect=3e-116]} {Dmel: FBgn0010333, Rac1, [RH, Score=340, Expect=7e-121]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=320, Expect=4e-113]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [RH, Score=315, Expect=2e-111]} {RNA1509_40868} {RNA1310_28906.1} {RNA815_13153}
36. MligTC455_44762 1411 29.4 Mlig455_054505, Mlig455_055363

Neo: -

Age: -

Region-enriched R4: 1.455/0.00954
Region-enriched R3: 1.386/0.00533
Region-enriched R5: 1.323/0.00126

TMEM144 1.797 - - - 0.969 - 0.828

Mlig455_054505 {REF} {Length: 1727} {Pfam: Transmembrane family, TMEM144 of transporters [PF07857.14, score=343.3]; Sugar transport protein [PF06800.14, score=32.7]} {Human: ENSG00000164124, TMEM144, transmembrane protein 144, [RH, Score=263, Expect=1e-84]} {Mouse: ENSMUSG00000027956, Tmem144, transmembrane protein 144, [RH, Score=274, Expect=3e-89]} {Celegans: WBGene00020096, R144.6, Transmembrane protein 144 homolog, [RH, Score=249, Expect=7e-80]} {Smed: dd_Smed_v6_4971_0_1, dd_Smed_v6_4971_0_1, [RH, Score=223, Expect=3e-69]} {RNA1509_20314} {RNA1310_19532, RNA1509_20314} {RNA1509_20314, RNA815_8427}

Mlig455_055363 {REF} {Length: 1660} {Pfam: Transmembrane family, TMEM144 of transporters [PF07857.14, score=343.3]; Sugar transport protein [PF06800.14, score=32.7]} {Human: ENSG00000164124, TMEM144, transmembrane protein 144, [RH, Score=263, Expect=1e-84]} {Mouse: ENSMUSG00000027956, Tmem144, transmembrane protein 144, [RH, Score=274, Expect=3e-89]} {Celegans: WBGene00020096, R144.6, Transmembrane protein 144 homolog, [RH, Score=249, Expect=7e-80]} {Smed: dd_Smed_v6_4971_0_1, dd_Smed_v6_4971_0_1, [RH, Score=223, Expect=3e-69]} {RNA1509_20314, RNA1509_24963, RNA1509_31718} {RNA1310_19532, RNA1509_24963, RNA1509_31718} {RNA1509_24963, RNA1509_31718, RNA815_8427}
37. MligTC455_19467 366 7.63 Mlig455_064830

Neo: -

Age: -

Region-enriched R4: 2.976/0.00386

TRPM6 1.796 - - 0.831 - - 0.965 Mlig455_064830 {REF} {Length: 6830} {Pfam: SLOG in TRPM [PF18139.3, score=191.7]; SLOG in TRPM, prokaryote [PF18171.3, score=75.5]; Ion transport protein [PF00520.33, score=48.1]} {Human: ENSG00000119121, TRPM6, transient receptor potential cation channel subfamily M member 6, [Score=401, Expect=3e-115]} {Mouse: ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [RH, Score=416, Expect=2e-121]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=402, Expect=2e-119]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=323, Expect=1e-90]} {Smed: dd_Smed_v6_11259_0_12, dd_Smed_v6_11259_0_12, [RH, Score=498, Expect=4e-155]} {RNA1509_8221} {RNA1310_1347, RNA1509_8221} {RNA1509_8221, RNA815_794}
38. MligTC455_44763 706 14.71 Mlig455_055422

Neo: -

Age: -

Region-enriched R4: 1.754/0.00115
Region-enriched R5: 1.353/0.00093
Region-enriched R3: 1.299/0.01581

TMEM144 1.795 - - - 0.969 - 0.826 Mlig455_055422 {REF} {Length: 1371} {Pfam: Transmembrane family, TMEM144 of transporters [PF07857.14, score=121.8]} {Human: ENSG00000164124, TMEM144, transmembrane protein 144, [Score=89.7, Expect=2e-19]} {Mouse: ENSMUSG00000027956, Tmem144, transmembrane protein 144, [Score=97.4, Expect=2e-22]} {Celegans: WBGene00020096, R144.6, Transmembrane protein 144 homolog, [Score=102, Expect=2e-24]} {Smed: dd_Smed_v6_4971_0_1, dd_Smed_v6_4971_0_1, [Score=102, Expect=1e-24]} {RNA1509_20314} {RNA1310_19532} {RNA815_8427}
39. MligTC455_26907 242 5.05 Mlig455_019220

Neo: -

Age: -

Region-enriched R3: 4.556/0.00000

F5 1.792 - - - - 0.832 0.960 Mlig455_019220 {REF} {Length: 5657} {Human: ENSG00000198734, F5, coagulation factor V, [Score=75.1, Expect=1e-12]} {RNA1509_28476, RNA1509_31695, RNA1509_39871} {RNA1310_25950, RNA1509_28476, RNA1509_31695, RNA1509_39871} {RNA1509_28476, RNA1509_31695, RNA1509_39871, RNA815_16964}
40. MligTC455_51957 427 8.9 Mlig455_001616

Neo: -

Age: logFC(26M/2M)=0.792

LCK 1.763 - 0.811 - - - 0.952 Mlig455_001616 {REF} {Length: 2834} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=195.1]; Protein kinase domain [PF00069.27, score=130.1]; Variant SH3 domain [PF14604.8, score=43.0]; SH2 domain [PF00017.26, score=42.8]; Variant SH3 domain [PF07653.19, score=36.6]; SH3 domain [PF00018.30, score=35.8]; ABC1 atypical kinase-like domain [PF03109.18, score=28.0]} {Human: ENSG00000182866, LCK, LCK proto-oncogene, Src family tyrosine kinase, [Score=251, Expect=7e-78]; ENSG00000101336, HCK, HCK proto-oncogene, Src family tyrosine kinase, [Score=250, Expect=5e-77]; ENSG00000254087, LYN, LYN proto-oncogene, Src family tyrosine kinase, [Score=241, Expect=1e-73]} {Mouse: ENSMUSG00000000409, Lck, lymphocyte protein tyrosine kinase, [Score=255, Expect=4e-79]; ENSMUSG00000042228, Lyn, LYN proto-oncogene, Src family tyrosine kinase, [Score=243, Expect=7e-75]} {Dmel: FBgn0264959, Src42A, Src oncogene at 42A, [Score=239, Expect=4e-73]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=213, Expect=5e-64]} {Smed: dd_Smed_v6_3363_0_2, dd_Smed_v6_3363_0_2, [Score=304, Expect=6e-99]} {RNA1509_10615, RNA1509_47356} {RNA1310_9006.1, RNA1509_47356} {RNA1509_47356, RNA815_3005.1}
41. MligTC455_49488 5075 105.73 Mlig455_055474

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.341

Region-enriched R3: 1.609/0.02116

1.761 - 0.800 - - - 0.961 Mlig455_055474 {REF} {Length: 988} {Pfam: Universal stress protein family [PF00582.28, score=100.4]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=126, Expect=2e-37]} {RNA1509_12747, RNA1509_15238} {RNA1310_22621, RNA1509_15238} {RNA1509_15238, RNA815_17247}
42. MligTC455_49487 5068 105.57 Mlig455_036283

Neo: -

Age: logFC(26M/2M)=-0.424

Region-enriched R3: 1.606/0.02613

1.76 - 0.800 - - - 0.960 Mlig455_036283 {REF} {Length: 978} {Pfam: Universal stress protein family [PF00582.28, score=89.7]} {Smed: dd_Smed_v6_402_1_1, dd_Smed_v6_402_1_1, [Score=109, Expect=3e-31]} {RNA1509_12747} {RNA1310_22621} {RNA815_17247}
43. MligTC455_20448 1045 21.77 Mlig455_053753

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.198

SLC2A3 1.742 - - 0.778 0.964 - - Mlig455_053753 {REF} {Length: 2905} {Pfam: Sugar (and other) transporter [PF00083.26, score=370.8]; Major Facilitator Superfamily [PF07690.18, score=76.6]} {Human: ENSG00000059804, SLC2A3, solute carrier family 2 member 3, [RH, Score=352, Expect=1e-115]; ENSG00000117394, SLC2A1, solute carrier family 2 member 1, [RH, Score=347, Expect=6e-114]; ENSG00000173262, SLC2A14, solute carrier family 2 member 14, [RH, Score=344, Expect=1e-112]} {Mouse: ENSMUSG00000028645, Slc2a1, solute carrier family 2 (facilitated glucose transporter), member 1, [RH, Score=346, Expect=1e-113]} {Dmel: FBgn0264574, Glut1, Glucose transporter 1, [RH, Score=412, Expect=1e-135]} {Celegans: WBGene00019207, fgt-1, Facilitated glucose transporter protein 1, [RH, Score=293, Expect=2e-93]} {Smed: dd_Smed_v6_8244_0_1, dd_Smed_v6_8244_0_1, [RH, Score=394, Expect=2e-132]} {RNA1509_24277, RNA1509_44652, RNA1509_45890} {RNA1310_5985.1, RNA1509_24277, RNA1509_44652, RNA1509_45890} {RNA1509_24277, RNA1509_44652, RNA1509_45890, RNA815_5376}
44. MligTC455_42353 5099 106.23 Mlig455_014274, Mlig455_014309, Mlig455_018673

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.786

Region-enriched R3: 2.226/0.00003

AC113554.1, ACE 1.737 - - 0.769 - - 0.968

Mlig455_014274 {REF} {Length: 2949} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_37062, RNA1509_441} {RNA1310_8949, RNA1509_37062} {RNA1509_37062, RNA815_4061}

Mlig455_014309 {REF} {Length: 2926} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=705.7]} {Human: ENSG00000159640, ACE, angiotensin I converting enzyme, [RH, Score=548, Expect=0.0]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [RH, Score=551, Expect=0.0]} {Dmel: FBgn0016122, Acer, Angiotensin-converting enzyme-related, [RH, Score=426, Expect=4e-141]} {Celegans: WBGene00000039, acn-1, Inactive angiotensin-converting enzyme-related protein, [Score=191, Expect=3e-51]} {Smed: dd_Smed_v6_3745_0_1, dd_Smed_v6_3745_0_1, [Score=411, Expect=1e-135]} {RNA1509_441} {RNA1310_8949} {RNA815_4061}

Mlig455_018673 {REF} {Length: 833} {Pfam: Angiotensin-converting enzyme [PF01401.20, score=122.4]} {Human: ENSG00000264813, AC113554.1, novel transcript, [Score=103, Expect=3e-24]; ENSG00000159640, ACE, angiotensin I converting enzyme, [Score=103, Expect=2e-24]} {Mouse: ENSMUSG00000020681, Ace, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, [Score=97.8, Expect=2e-22]; ENSMUSG00000101605, Ace3, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3, [Score=93.2, Expect=6e-21]} {Dmel: FBgn0012037, Ance, Angiotensin converting enzyme, [Score=74.7, Expect=7e-15]} {Smed: dd_Smed_v6_13804_0_1, dd_Smed_v6_13804_0_1, [Score=51.2, Expect=2e-07]} {RNA1509_16360} {RNA1310_8949} {RNA815_4061}
45. MligTC455_52558 968 20.17 Mlig455_024460

Neo: -

Age: -

ANXA13 1.737 - - - 0.777 0.960 - Mlig455_024460 {REF} {Length: 1894} {Pfam: Annexin [PF00191.22, score=272.9]} {Human: ENSG00000104537, ANXA13, annexin A13, [Score=258, Expect=1e-84]; ENSG00000196975, ANXA4, annexin A4, [Score=251, Expect=2e-81]} {Mouse: ENSMUSG00000029994, Anxa4, annexin A4, [Score=244, Expect=4e-79]; ENSMUSG00000021866, Anxa11, annexin A11, [Score=239, Expect=5e-75]; ENSMUSG00000021950, Anxa8, annexin A8, [Score=234, Expect=2e-75]} {Dmel: FBgn0030749, AnxB11, Annexin B11, [Score=244, Expect=3e-79]} {Celegans: WBGene00003589, nex-2, Annexin, [Score=219, Expect=5e-68]} {Smed: dd_Smed_v6_5798_0_1, dd_Smed_v6_5798_0_1, [Score=269, Expect=9e-85]} {RNA1509_21408, RNA1509_26616, RNA1509_29180} {RNA1310_4220.1, RNA1509_21408, RNA1509_26616, RNA1509_29180} {RNA1509_21408, RNA1509_26616, RNA1509_29180, RNA815_1223.1}
46. MligTC455_50036 1353 28.19 Mlig455_063714

Neo: -

Age: logFC(26M/2M)=-0.294

Region-enriched R4: 1.826/0.00071
Region-enriched R3: 1.745/0.00078
Region-enriched R5: 1.202/0.01353

SPHK1 1.728 - - 0.769 - - 0.959 Mlig455_063714 {REF} {Length: 3647} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=81.8]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [Score=152, Expect=4e-43]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=150, Expect=5e-44]; ENSMUSG00000057342, Sphk2, sphingosine kinase 2, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [RH, Score=145, Expect=1e-39]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [Score=120, Expect=2e-31]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [Score=127, Expect=3e-34]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
47. MligTC455_40820 1076 22.41 Mlig455_016774

Neo: -

Age: logFC(26M/2M)=0.366

Region-enriched R4: 1.989/0.00476

DCXR 1.715 0.763 - - - - 0.952 Mlig455_016774 {REF} {Length: 1162} {TRANSSPLICED} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=186.1]; short chain dehydrogenase [PF00106.27, score=156.4]; KR domain [PF08659.12, score=55.4]; NAD dependent epimerase/dehydratase family [PF01370.23, score=28.6]; RmlD substrate binding domain [PF04321.19, score=23.1]} {Human: ENSG00000169738, DCXR, dicarbonyl and L-xylulose reductase, [RH, Score=182, Expect=9e-57]} {Mouse: ENSMUSG00000039450, Dcxr, dicarbonyl L-xylulose reductase, [RH, Score=188, Expect=2e-59]} {Dmel: FBgn0030968, CG7322, [RH, Score=194, Expect=1e-61]} {Celegans: WBGene00000984, dhs-21, L-xylulose reductase, [RH, Score=204, Expect=9e-66]} {Smed: dd_Smed_v6_2263_0_1, dd_Smed_v6_2263_0_1, [RH, Score=183, Expect=1e-57]} {RNA1509_36359, RNA1509_42063, RNA1509_55127} {RNA1310_24446.2, RNA1509_36359, RNA1509_42063, RNA1509_55127} {RNA1509_36359, RNA1509_42063, RNA1509_55127, RNA815_13838}
48. MligTC455_40739 1244 25.91 Mlig455_005845

Neo: -

Age: logFC(26M/2M)=-0.318

Region-enriched R4: 2.303/0.00001
Region-enriched R5: 1.932/0.00000
Region-enriched R3: 1.599/0.00189
Region-enriched R6: 1.539/0.00828

Regeneration-upregulated BL: 2.384

Regeneration-enriched BL: 2.384

HAAO 1.71 - - 0.760 - - 0.950 Mlig455_005845 {REF} {Length: 1402} {TRANSSPLICED} {Pfam: 3-hydroxyanthranilic acid dioxygenase [PF06052.14, score=168.6]} {Human: ENSG00000162882, HAAO, 3-hydroxyanthranilate 3,4-dioxygenase, [RH, Score=204, Expect=6e-64]} {Mouse: ENSMUSG00000000673, Haao, 3-hydroxyanthranilate 3,4-dioxygenase, [RH, Score=216, Expect=1e-68]} {Celegans: WBGene00010595, haao-1, 3-hydroxyanthranilate 3,4-dioxygenase, [RH, Score=160, Expect=5e-47]} {Smed: dd_Smed_v6_3032_0_1, dd_Smed_v6_3032_0_1, [RH, Score=140, Expect=1e-39]} {RNA1509_15849, RNA1509_27109} {RNA1310_23508, RNA1509_15849, RNA1509_27109} {RNA1509_15849, RNA1509_27109, RNA815_8418}
49. MligTC455_43756 3225 67.19 Mlig455_010402

Neo: -

Age: -

Region-enriched R3: 1.722/0.00762

1.708 - - 0.747 - - 0.961 Mlig455_010402 {REF} {Length: 2001} {Pfam: Innexin [PF00876.20, score=339.7]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=100, Expect=3e-23]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=291, Expect=2e-95]} {Smed: dd_Smed_v6_734_0_2, dd_Smed_v6_734_0_2, [Score=292, Expect=3e-95]} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1310_16777, RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855} {RNA1509_21594, RNA1509_22136, RNA1509_30214, RNA1509_32964, RNA1509_3943, RNA1509_49855, RNA815_7295}
50. MligTC455_37964 3298 68.72 Mlig455_056045

Neo: -

Age: logFC(26M/2M)=1.465

HSD17B4 1.706 0.754 - - - - 0.952 Mlig455_056045 {REF} {Length: 2688} {Pfam: short chain dehydrogenase [PF00106.27, score=134.8]; Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=112.0]; MaoC like domain [PF01575.21, score=101.4]; SCP-2 sterol transfer family [PF02036.19, score=70.6]; KR domain [PF08659.12, score=53.8]} {Human: ENSG00000133835, HSD17B4, hydroxysteroid 17-beta dehydrogenase 4, [RH, Score=810, Expect=0.0]} {Mouse: ENSMUSG00000024507, Hsd17b4, hydroxysteroid (17-beta) dehydrogenase 4, [RH, Score=781, Expect=0.0]} {Dmel: FBgn0030731, Mfe2, peroxisomal Multifunctional enzyme type 2, [RH, Score=595, Expect=0.0]} {Celegans: WBGene00000991, dhs-28, DeHydrogenases, Short chain, [RH, Score=358, Expect=1e-116]} {Smed: dd_Smed_v6_5867_0_1, dd_Smed_v6_5867_0_1, [RH, Score=605, Expect=0.0]} {RNA1509_9012} {RNA1310_590.1} {RNA815_2204}
51. MligTC455_50035 432 9 Mlig455_000039

Neo: -

Age: Up-Down-Up

Region-enriched R4: 2.574/0.01215

SPHK1 1.695 0.743 - - - - 0.952 Mlig455_000039 {REF} {Length: 2459} {TRANSSPLICED} {Pfam: Diacylglycerol kinase catalytic domain [PF00781.26, score=79.4]; YegS C-terminal NAD kinase beta sandwich-like domain [PF19279.1, score=29.9]} {Human: ENSG00000176170, SPHK1, sphingosine kinase 1, [RH, Score=215, Expect=5e-64]} {Mouse: ENSMUSG00000061878, Sphk1, sphingosine kinase 1, [RH, Score=206, Expect=1e-60]} {Dmel: FBgn0030300, Sk1, Sphingosine kinase 1, [Score=142, Expect=1e-35]} {Celegans: WBGene00007918, sphk-1, Sphingosine kinase 1, [RH, Score=149, Expect=5e-39]} {Smed: dd_Smed_v6_5736_0_1, dd_Smed_v6_5736_0_1, [RH, Score=174, Expect=1e-48]} {RNA1509_19326} {RNA1310_4471} {RNA815_1161}
52. MligTC455_37946 163 3.4 Mlig455_026377

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.753

Region-enriched R4: 3.957/0.00047

1.694 - - 0.974 - 0.720 - Mlig455_026377 {REF} {Length: 1756} {RNA1509_17190} {RNA1310_14110, RNA1509_17190} {RNA1509_17190, RNA815_23203}
53. MligTC455_47835 636 13.24 Mlig455_043525

Neo: -

Age: -

Region-enriched R3: 2.659/0.00001
Region-enriched R6: 2.142/0.00461
Region-enriched R5: 1.917/0.00072

1.693 - 0.731 - - - 0.962 Mlig455_043525 {REF} {Length: 1356} {RNA1509_18381, RNA1509_27428, RNA1509_57910} {RNA1310_28727.1, RNA1509_18381, RNA1509_27428, RNA1509_57910} {RNA1509_18381, RNA1509_27428, RNA1509_57910, RNA815_19848}
54. MligTC455_18428 1616 33.66 Mlig455_065427, Mlig455_067904

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.309/0.00143

GTPBP10 1.687 - - 0.729 0.958 - -

Mlig455_065427 {REF} {Length: 1291} {TRANSSPLICED} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=74.5]; GTP1/OBG [PF01018.24, score=63.5]; Ferrous iron transport protein B [PF02421.20, score=36.1]} {Human: ENSG00000105793, GTPBP10, GTP binding protein 10, [RH, Score=269, Expect=5e-87]} {Mouse: ENSMUSG00000040464, Gtpbp10, GTP-binding protein 10 (putative), [RH, Score=257, Expect=8e-83]} {Dmel: FBgn0032818, CG10628, [RH, Score=266, Expect=3e-86]} {Celegans: WBGene00016145, C26E6.12, [RH, Score=200, Expect=1e-60]} {Smed: dd_Smed_v6_8458_0_1, dd_Smed_v6_8458_0_1, [RH, Score=291, Expect=1e-96]} {RNA1509_22530, RNA1509_48775} {RNA1310_25778.1, RNA1509_22530, RNA1509_48775} {RNA1509_22530, RNA1509_48775, RNA815_11704}

Mlig455_067904 {REF} {Length: 1152} {TRANSSPLICED} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=75.2]; Ferrous iron transport protein B [PF02421.20, score=37.1]} {Human: ENSG00000105793, GTPBP10, GTP binding protein 10, [Score=217, Expect=1e-67]} {Mouse: ENSMUSG00000040464, Gtpbp10, GTP-binding protein 10 (putative), [Score=205, Expect=1e-63]} {Dmel: FBgn0032818, CG10628, [Score=216, Expect=9e-68]} {Celegans: WBGene00016145, C26E6.12, [Score=168, Expect=2e-49]} {Smed: dd_Smed_v6_8458_0_1, dd_Smed_v6_8458_0_1, [Score=238, Expect=1e-76]} {RNA1509_48775} {RNA1310_25778.1} {RNA815_11704}
55. MligTC455_02591 1760 36.66 Mlig455_027318

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.783

MX1 1.681 - 0.727 - 0.954 - - Mlig455_027318 {REF} {Length: 5190} {Pfam: Dynamin central region [PF01031.22, score=152.2]; Dynamin GTPase effector domain [PF02212.20, score=57.4]; Family with sequence similarity 184, A and B [PF15665.7, score=20.6]} {Human: ENSG00000157601, MX1, MX dynamin like GTPase 1, [Score=136, Expect=2e-34]; ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=132, Expect=4e-33]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=144, Expect=3e-37]} {RNA1509_8812} {RNA1310_1482.2} {RNA815_3194}
56. MligTC455_52436 4103 85.47 Mlig455_036594, Mlig455_057758

Neo: -

Age: -

Region-enriched R3: 2.299/0.00029

FMO4 1.666 - 0.713 - - - 0.953

Mlig455_036594 {REF} {Length: 1772} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=121.5]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=43.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=21.1]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=104, Expect=1e-23]} {Mouse: ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=102, Expect=5e-23]; ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=102, Expect=3e-23]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=132, Expect=3e-34]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=1e-25]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=93.2, Expect=1e-20]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}

Mlig455_057758 {REF} {Length: 1759} {TRANSSPLICED} {Pfam: Flavin-binding monooxygenase-like [PF00743.21, score=125.0]; Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=49.5]; FAD-NAD(P)-binding [PF13454.8, score=29.2]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=28.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.1]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=19.0]; FAD dependent oxidoreductase [PF01266.26, score=18.3]} {Human: ENSG00000076258, FMO4, flavin containing monooxygenase 4, [Score=111, Expect=1e-25]} {Mouse: ENSMUSG00000028088, Fmo5, flavin containing monooxygenase 5, [Score=113, Expect=2e-26]; ENSMUSG00000026560, Fmo9, flavin containing monooxygenase 9, [Score=108, Expect=6e-25]} {Dmel: FBgn0033079, Fmo-2, Flavin-containing monooxygenase 2, [Score=148, Expect=1e-39]} {Celegans: WBGene00016728, C46H11.2, Flavin-containing monooxygenase, [Score=108, Expect=9e-26]} {Smed: dd_Smed_v6_9449_0_1, dd_Smed_v6_9449_0_1, [Score=106, Expect=6e-25]} {RNA1509_13926} {RNA1310_13123.1} {RNA815_5157.1}
57. MligTC455_32556 3264 68 Mlig455_063887

Neo: -

Age: logFC(26M/2M)=0.287

Region-enriched R3: 2.356/0.00263

PRSS12 0.984 - - - 0.984 - - Mlig455_063887 {REF} {Length: 4839} {Pfam: Scavenger receptor cysteine-rich domain [PF00530.20, score=61.5]; Kringle domain [PF00051.20, score=54.5]; Low-density lipoprotein receptor domain class A [PF00057.20, score=44.2]; Lectin C-type domain [PF00059.23, score=26.4]; Scavenger receptor cysteine-rich domain [PF15494.8, score=21.1]} {Human: ENSG00000164099, PRSS12, serine protease 12, [Score=64.7, Expect=4e-10]; ENSG00000138131, LOXL4, lysyl oxidase like 4, [Score=63.2, Expect=2e-09]; ENSG00000115318, LOXL3, lysyl oxidase like 3, [Score=62.8, Expect=1e-10]} {Mouse: ENSMUSG00000027978, Prss12, protease, serine 12 neurotrypsin (motopsin), [Score=68.2, Expect=3e-11]; ENSMUSG00000021260, Hhipl1, hedgehog interacting protein-like 1, [Score=65.9, Expect=1e-10]} {Dmel: FBgn0023479, teq, Tequila, [Score=72.0, Expect=1e-12]} {Celegans: WBGene00003072, lrp-2, Low-density lipoprotein RecePtor related, [Score=63.2, Expect=8e-10]} {Smed: dd_Smed_v6_790_0_1, dd_Smed_v6_790_0_1, [Score=222, Expect=1e-60]} {RNA1509_337, RNA1509_44538, RNA1509_49914} {RNA1310_1502.1, RNA1509_337, RNA1509_44538, RNA1509_49914} {RNA1509_337, RNA1509_44538, RNA1509_49914, RNA815_422}
58. MligTC455_21829 5023 104.65 Mlig455_014094

Neo: -

Age: -

Region-enriched R4: 1.409/0.02548
Region-enriched R3: 1.341/0.03362

0.976 - - - 0.976 - - Mlig455_014094 {REF} {Length: 3099} {Pfam: Ependymin [PF00811.20, score=62.5]} {RNA1509_29432} {RNA1310_26645, RNA1509_29432} {RNA1509_29432, RNA815_4988.2}
59. MligTC455_15834 643 13.39 Mlig455_048189

Neo: -

Age: Down-Up-Down

Region-enriched R3: 1.774/0.04353

CHP1 0.975 - - - 0.975 - - Mlig455_048189 {REF} {Length: 1979} {Pfam: EF-hand domain pair [PF13499.8, score=40.0]; EF-hand domain [PF13405.8, score=31.0]; EF hand [PF00036.34, score=26.8]; EF hand [PF13202.8, score=18.4]} {Human: ENSG00000187446, CHP1, calcineurin like EF-hand protein 1, [Score=78.2, Expect=4e-18]} {Mouse: ENSMUSG00000014077, Chp1, calcineurin-like EF hand protein 1, [Score=78.6, Expect=2e-18]} {Dmel: FBgn0037358, elm, ethanol sensitive with low memory, [Score=85.1, Expect=5e-21]} {Celegans: WBGene00014109, chpf-1, Calcineurin-like EF-Hand Protein Family member, [Score=73.9, Expect=6e-17]} {Smed: dd_Smed_v6_1504_0_1, dd_Smed_v6_1504_0_1, [Score=83.6, Expect=1e-20]} {RNA1509_34816, RNA1509_7124} {RNA1310_4339.1, RNA1509_34816} {RNA1509_34816, RNA815_12801}
60. MligTC455_33338 2063 42.98 Mlig455_036458

Neo: -

Age: Up-Up-Up, logFC(26M/2M)=1.535

0.965 - - - - - 0.965 Mlig455_036458 {REF} {Length: 2777} {Pfam: Lectin C-type domain [PF00059.23, score=21.8]} {Celegans: WBGene00016619, C43H6.6, [RH, Score=53.1, Expect=1e-07]} {RNA1509_14330, RNA1509_1885, RNA1509_24003} {RNA1310_13442.1, RNA1509_14330, RNA1509_1885, RNA1509_24003} {RNA1509_14330, RNA1509_1885, RNA1509_24003, RNA815_1168}
61. MligTC455_34149 212 4.42 Mlig455_021935

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.632

Region-enriched R3: 4.071/0.00072

0.963 - - - - - 0.963 Mlig455_021935 {REF} {Length: 24770} {Pfam: FKBP26_C-terminal [PF18046.3, score=37.4]; Galactoside-binding lectin [PF00337.24, score=30.4]; Retroviral envelope protein [PF00517.19, score=20.0]} {RNA1509_23521} {RNA1310_3139} {RNA815_894}
62. MligTC455_35217 5138 107.05 Mlig455_014282, Mlig455_014335

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.399

Region-enriched R3: 1.348/0.01129

0.959 - - - - - 0.959

Mlig455_014282 {REF} {Length: 1807} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=158.0]} {RNA1509_22501, RNA1509_4768} {RNA1310_7742.1, RNA1509_22501} {RNA1509_22501, RNA815_6411}

Mlig455_014335 {REF} {Length: 1769} {TRANSSPLICED} {Pfam: Transferase family [PF02458.17, score=159.5]} {RNA1509_4768} {RNA1310_7742.1} {RNA815_6411}
63. MligTC455_21091 1066 22.21 Mlig455_045138

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.653

TRPM1 0.958 - - - 0.958 - - Mlig455_045138 {REF} {Length: 4149} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=64.1]; Ankyrin repeats (many copies) [PF13637.8, score=58.6]; Ankyrin repeats (many copies) [PF13857.8, score=52.1]; Ion transport protein [PF00520.33, score=47.2]; Ankyrin repeat [PF13606.8, score=38.6]; Ankyrin repeat [PF00023.32, score=35.0]} {Human: ENSG00000274965, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=161, Expect=2e-39]; ENSG00000134160, TRPM1, transient receptor potential cation channel subfamily M member 1, [Score=161, Expect=2e-39]; ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=154, Expect=5e-37]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=157, Expect=3e-38]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=153, Expect=5e-37]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=117, Expect=3e-26]} {Celegans: WBGene00001796, gtl-2, Gon-Two Like (TRP subfamily), [Score=82.4, Expect=1e-15]} {Smed: dd_Smed_v6_8382_0_1, dd_Smed_v6_8382_0_1, [Score=179, Expect=9e-46]} {RNA1509_3562} {RNA1310_2118.1} {RNA815_362.1}
64. MligTC455_21272 4347 90.56 Mlig455_003588

Neo: -

Age: -

Region-enriched R3: 1.729/0.00219
Region-enriched R5: 1.335/0.01435

SLC5A8 0.956 - - - 0.956 - - Mlig455_003588 {REF} {Length: 5902} {Pfam: Sodium:solute symporter family [PF00474.19, score=128.2]} {Human: ENSG00000262217, SLC5A8, solute carrier family 5 member 8, [Score=373, Expect=2e-120]; ENSG00000256870, SLC5A8, solute carrier family 5 member 8, [Score=373, Expect=2e-120]; ENSG00000138074, SLC5A6, solute carrier family 5 member 6, [Score=367, Expect=2e-117]; ENSG00000148942, SLC5A12, solute carrier family 5 member 12, [Score=358, Expect=1e-114]} {Mouse: ENSMUSG00000020062, Slc5a8, solute carrier family 5 (iodide transporter), member 8, [Score=377, Expect=6e-122]; ENSMUSG00000041644, Slc5a12, solute carrier family 5 (sodium/glucose cotransporter), member 12, [Score=363, Expect=2e-116]} {Dmel: FBgn0034494, CG10444, [Score=330, Expect=2e-104]} {Celegans: WBGene00014092, ZK822.5, [Score=226, Expect=2e-65]} {Smed: dd_Smed_v6_14173_0_1, dd_Smed_v6_14173_0_1, [Score=345, Expect=2e-110]} {RNA1509_1120} {RNA1310_5768} {RNA815_1831}
65. MligTC455_49659 4741 98.77 Mlig455_011512, Mlig455_050003

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.314

Region-enriched R3: 1.923/0.00380

0.956 - - - - - 0.956

Mlig455_011512 {REF} {Length: 2299} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}

Mlig455_050003 {REF} {Length: 1812} {RNA1509_3964} {RNA1310_32368} {RNA815_14237.1}
66. MligTC455_24208 1280 26.67 Mlig455_044686

Neo: Int S/G2/M

Age: -

NOA1 0.955 - - - 0.955 - - Mlig455_044686 {REF} {Length: 4506} {Pfam: 50S ribosome-binding GTPase [PF01926.25, score=26.6]} {Human: ENSG00000084092, NOA1, nitric oxide associated 1, [RH, Score=194, Expect=4e-52]} {Mouse: ENSMUSG00000036285, Noa1, nitric oxide associated 1, [RH, Score=202, Expect=4e-55]} {Dmel: FBgn0034307, CG10914, [RH, Score=212, Expect=4e-59]} {Celegans: WBGene00013001, Y48E1B.2, [RH, Score=182, Expect=5e-48]} {Smed: dd_Smed_v6_9367_0_2, dd_Smed_v6_9367_0_2, [RH, Score=185, Expect=9e-50]} {RNA1509_16646} {RNA1310_6110.1} {RNA815_4736}

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