Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_36709 | 3794 | 79.04 | Mlig455_059511 | Neo: - Age: Down-Up-Up Region-enriched R4: 1.064/0.00002 |
TXN2 | Mlig455_059511 {REF} {Length: 986} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=66.7]} {Human: ENSG00000100348, TXN2, thioredoxin 2, [RH, Score=102, Expect=4e-27]} {Mouse: ENSMUSG00000005354, Txn2, thioredoxin 2, [RH, Score=100, Expect=4e-27]} {Dmel: FBgn0035334, CG8993, [RH, Score=81.3, Expect=2e-19]} {Celegans: WBGene00007099, trx-2, Probable thioredoxin-2, [Score=79.7, Expect=4e-19]} {Smed: dd_Smed_v6_872_0_1, dd_Smed_v6_872_0_1, [RH, Score=89.7, Expect=3e-23]} {RNA1509_7447, RNA1509_8127} {RNA1310_36313.1, RNA1509_7447} {RNA1509_7447, RNA815_10101.2} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.849 | 6.47 | 0.08242 | 0.62614 | |
RegionR2 | -0.681 | 6.47 | 0.00367 | 0.05246 | |
RegionR3 | 0.379 | 6.47 | 0.04028 | 0.34950 | |
RegionR4 | 1.064 | 6.47 | 0.00000 | 0.00002 | |
RegionR5 | 0.688 | 6.47 | 0.00007 | 0.00126 | |
RegionR6 | 0.587 | 6.47 | 0.00155 | 0.05114 | |
RegionR7 | -0.658 | 6.47 | 0.00975 | 0.16881 | |
RegionR8 | -0.529 | 6.47 | 0.08274 | 0.54567 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.812 | 6.47 | 0.28348 | 0.98316 | |
RegenerationR2 | -0.242 | 6.47 | 0.25448 | 0.70111 | |
RegenerationR3 | -0.319 | 6.47 | 0.13407 | 0.55780 | |
RegenerationR4 | -0.307 | 6.47 | 0.15632 | 0.58749 | |
RegenerationR5 | -0.323 | 6.47 | 0.11354 | 0.50801 | |
RegenerationR6 | -0.218 | 6.47 | 0.30896 | 0.65719 | |
RegenerationBL | 0.011 | 6.47 | 0.96383 | 1.00000 | |
RegenerationTP | -0.104 | 6.47 | 0.71739 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_36709 | 3794 | 79.04 | Mlig455_059511 | Neo: - Age: Down-Up-Up Region-enriched R4: 1.064/0.00002 |
TXN2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_059511 {REF} {Length: 986} {TRANSSPLICED} {Pfam: Thioredoxin [PF00085.22, score=66.7]} {Human: ENSG00000100348, TXN2, thioredoxin 2, [RH, Score=102, Expect=4e-27]} {Mouse: ENSMUSG00000005354, Txn2, thioredoxin 2, [RH, Score=100, Expect=4e-27]} {Dmel: FBgn0035334, CG8993, [RH, Score=81.3, Expect=2e-19]} {Celegans: WBGene00007099, trx-2, Probable thioredoxin-2, [Score=79.7, Expect=4e-19]} {Smed: dd_Smed_v6_872_0_1, dd_Smed_v6_872_0_1, [RH, Score=89.7, Expect=3e-23]} {RNA1509_7447, RNA1509_8127} {RNA1310_36313.1, RNA1509_7447} {RNA1509_7447, RNA815_10101.2} |
2. | MligTC455_41720 | 3651 | 76.05 | Mlig455_059515 | Neo: - Age: Down-Down-Up Region-enriched R4: 1.422/0.00269 |
HPGDS | 2.617 | - | - | - | 0.958 | 0.886 | 0.773 | Mlig455_059515 {REF} {Length: 981} {TRANSSPLICED} {Pfam: Glutathione S-transferase, C-terminal domain [PF14497.8, score=49.1]; Glutathione S-transferase, C-terminal domain [PF00043.27, score=40.7]; Glutathione S-transferase, N-terminal domain [PF02798.22, score=25.4]} {Human: ENSG00000163106, HPGDS, hematopoietic prostaglandin D synthase, [Score=82.0, Expect=7e-19]; ENSG00000084207, GSTP1, glutathione S-transferase pi 1, [Score=79.7, Expect=7e-18]} {Mouse: ENSMUSG00000097830, Gstp1, glutathione S-transferase, pi 1, [Score=80.9, Expect=2e-18]; ENSMUSG00000060803, Gstp1, glutathione S-transferase, pi 1, [Score=80.9, Expect=2e-18]} {Dmel: FBgn0010226, GstS1, Glutathione S transferase S1, [Score=70.5, Expect=1e-14]} {Celegans: WBGene00001789, gst-41, Glutathione S-Transferase, [Score=89.4, Expect=5e-22]} {Smed: dd_Smed_v6_816_0_1, dd_Smed_v6_816_0_1, [Score=68.2, Expect=3e-14]} {RNA1509_9144, RNA1509_9822} {RNA1310_35676, RNA1509_9144, RNA1509_9822} {RNA1509_9144, RNA1509_9822, RNA815_16772.1} |
3. | MligTC455_49069 | 3685 | 76.77 | Mlig455_070251 | Neo: - Age: logFC(26M/2M)=0.212 Region-enriched R4: 1.746/0.00071 |
CS | 1.866 | - | - | - | 0.951 | 0.915 | - | Mlig455_070251 {REF} {Length: 2221} {TRANSSPLICED} {Pfam: Citrate synthase, C-terminal domain [PF00285.23, score=347.7]} {Human: ENSG00000062485, CS, citrate synthase, [RH, Score=701, Expect=0.0]} {Mouse: ENSMUSG00000005683, Cs, citrate synthase, [RH, Score=699, Expect=0.0]; ENSMUSG00000046934, Csl, citrate synthase like, [RH, Score=687, Expect=0.0]} {Dmel: FBgn0261955, kdn, knockdown, [RH, Score=694, Expect=0.0]} {Celegans: WBGene00000833, cts-1, Probable citrate synthase, mitochondrial, [RH, Score=641, Expect=0.0]} {Smed: dd_Smed_v6_335_0_1, dd_Smed_v6_335_0_1, [RH, Score=706, Expect=0.0]} {RNA1509_762} {RNA1310_11494.1} {RNA815_3764.1} |
4. | MligTC455_46060 | 5515 | 114.89 | Mlig455_020392, Mlig455_028391, Mlig455_028425, Mlig455_058436 | Neo: - Age: Down-Down-Up Region-enriched R3: 1.963/0.00990 |
1.827 | - | - | - | - | 0.971 | 0.856 | Mlig455_020392 {REF} {Length: 1388} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=2e-06]} {RNA1509_9885} {RNA1310_5794.1} {RNA815_1706} Mlig455_028391 {REF} {Length: 1388} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=2e-06]} {RNA1509_9885} {RNA1310_5794.1} {RNA815_1706} Mlig455_028425 {REF} {Length: 1390} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=2e-06]} {RNA1509_9885} {RNA1310_5794.1} {RNA815_1706} Mlig455_058436 {REF} {Length: 1395} {Pfam: Sleepless protein [PF17064.7, score=21.0]} {Smed: dd_Smed_v6_3595_0_1, dd_Smed_v6_3595_0_1, [RH, Score=44.7, Expect=3e-06]} {RNA1509_8861, RNA1509_9885} {RNA1310_5794.1, RNA1509_8861, RNA1509_9885} {RNA1509_8861, RNA1509_9885, RNA815_1706} |
|
5. | MligTC455_20913 | 14492 | 301.92 | Mlig455_002399, Mlig455_054651 | Neo: - |
RPS12 | 1.754 | - | - | - | 0.960 | 0.794 | - | Mlig455_002399 {REF} {Length: 786} {TRANSSPLICED} {Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family [PF01248.28, score=96.7]} {Human: ENSG00000112306, RPS12, ribosomal protein S12, [Score=160, Expect=3e-51]} {Mouse: ENSMUSG00000061983, Rps12, ribosomal protein S12, [Score=160, Expect=2e-51]; ENSMUSG00000067038, Rps12-ps3, ribosomal protein S12, pseudogene 3, [Score=160, Expect=2e-51]} {Dmel: FBgn0260441, RpS12, Ribosomal protein S12, [Score=142, Expect=2e-44]} {Celegans: WBGene00004481, rps-12, 40S ribosomal protein S12, [Score=120, Expect=5e-36]} {Smed: dd_Smed_v6_94979_0_1, dd_Smed_v6_94979_0_1, [Score=153, Expect=3e-49]} {RNA1509_1190} {RNA1310_46273, RNA1509_1190} {RNA1509_1190, RNA815_22452.1} Mlig455_054651 {REF} {Length: 758} {TRANSSPLICED} {Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family [PF01248.28, score=96.7]} {Human: ENSG00000112306, RPS12, ribosomal protein S12, [Score=160, Expect=3e-51]} {Mouse: ENSMUSG00000067038, Rps12-ps3, ribosomal protein S12, pseudogene 3, [Score=160, Expect=2e-51]; ENSMUSG00000061983, Rps12, ribosomal protein S12, [Score=160, Expect=2e-51]} {Dmel: FBgn0260441, RpS12, Ribosomal protein S12, [Score=142, Expect=2e-44]} {Celegans: WBGene00004481, rps-12, 40S ribosomal protein S12, [Score=121, Expect=3e-36]} {Smed: dd_Smed_v6_94979_0_1, dd_Smed_v6_94979_0_1, [Score=153, Expect=3e-49]} {RNA1509_44047, RNA1509_4432} {RNA1310_49080, RNA1509_44047, RNA1509_4432} {RNA1509_44047, RNA1509_4432, RNA815_22452.2} |
6. | MligTC455_23025 | 1509 | 31.43 | Mlig455_000988 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=0.920 Region-enriched R4: 1.884/0.00009 |
DHRS4 | 1.713 | - | - | - | - | 0.950 | 0.763 | Mlig455_000988 {REF} {Length: 1155} {Pfam: Enoyl-(Acyl carrier protein) reductase [PF13561.8, score=216.8]; short chain dehydrogenase [PF00106.27, score=169.8]; KR domain [PF08659.12, score=38.4]} {Human: ENSG00000284807, DHRS4, dehydrogenase/reductase 4, [RH, Score=260, Expect=7e-87]; ENSG00000157326, DHRS4, dehydrogenase/reductase 4, [RH, Score=260, Expect=7e-87]} {Mouse: ENSMUSG00000022210, Dhrs4, dehydrogenase/reductase (SDR family) member 4, [RH, Score=261, Expect=2e-87]} {Dmel: FBgn0035588, CG10672, [RH, Score=276, Expect=9e-93]} {Celegans: WBGene00000976, dhs-13, DeHydrogenases, Short chain, [RH, Score=254, Expect=5e-85]} {Smed: dd_Smed_v6_6646_0_1, dd_Smed_v6_6646_0_1, [RH, Score=261, Expect=4e-88]} {RNA1509_20367} {RNA1310_32758.1, RNA1509_20367} {RNA1509_20367, RNA815_14440.1} |
7. | MligTC455_51345 | 1637 | 34.11 | Mlig455_062128 | Neo: - Age: Down-Up-Down |
PRDX5 | 1.681 | - | - | - | 0.954 | - | 0.727 | Mlig455_062128 {REF} {Length: 2414} {TRANSSPLICED} {Pfam: Redoxin [PF08534.12, score=108.5]; AhpC/TSA family [PF00578.23, score=44.1]} {Human: ENSG00000126432, PRDX5, peroxiredoxin 5, [Score=132, Expect=8e-39]} {Mouse: ENSMUSG00000024953, Prdx5, peroxiredoxin 5, [Score=123, Expect=2e-35]} {Dmel: FBgn0038570, Prx5, Peroxiredoxin 5, [Score=139, Expect=4e-42]} {Smed: dd_Smed_v6_1290_0_1, dd_Smed_v6_1290_0_1, [Score=157, Expect=2e-49]} {RNA1509_12993, RNA1509_12998, RNA1509_15064, RNA1509_15980, RNA1509_20667, RNA1509_4959} {RNA1310_37609, RNA1509_12993, RNA1509_12998, RNA1509_15064, RNA1509_15980, RNA1509_20667, RNA1509_4959} {RNA1509_12993, RNA1509_12998, RNA1509_15064, RNA1509_15980, RNA1509_20667, RNA1509_4959, RNA815_25605} |
8. | MligTC455_54235 | 6425 | 133.86 | Mlig455_005204 | Neo: - Age: logFC(26M/2M)=0.258 |
0.968 | - | - | - | 0.968 | - | - | Mlig455_005204 {REF} {Length: 1035} {TRANSSPLICED} {Pfam: Shadow of prion protein, neuroprotective [PF14999.8, score=20.7]} {RNA1509_1933} {RNA1310_32718} {RNA815_15584} | |
9. | MligTC455_07911 | 3223 | 67.15 | Mlig455_056355, Mlig455_056368 | Neo: - Age: Down-Up-Down |
0.966 | - | - | - | 0.966 | - | - | Mlig455_056355 {REF} {Length: 1592} {Pfam: Immediate early response protein (IER) [PF05760.14, score=28.5]} {RNA1509_18831, RNA1509_32087} {RNA1310_34308, RNA1509_32087} {RNA1509_32087, RNA815_15730} Mlig455_056368 {REF} {Length: 1599} {Pfam: Immediate early response protein (IER) [PF05760.14, score=24.4]} {RNA1509_18831, RNA1509_36483} {RNA1310_34308, RNA1509_18831, RNA1509_36483} {RNA1509_18831, RNA1509_36483, RNA815_15730} |
|
10. | MligTC455_46843 | 909 | 18.94 | Mlig455_045276 | Neo: - Age: - |
NAGA | 0.962 | - | - | - | 0.962 | - | - | Mlig455_045276 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: Alpha galactosidase A [PF16499.7, score=416.2]; Alpha galactosidase A C-terminal beta sandwich domain [PF17450.4, score=31.3]; Melibiase [PF02065.20, score=25.4]} {Human: ENSG00000198951, NAGA, alpha-N-acetylgalactosaminidase, [RH, Score=351, Expect=9e-118]; ENSG00000102393, GLA, galactosidase alpha, [RH, Score=336, Expect=1e-111]} {Mouse: ENSMUSG00000022453, Naga, N-acetyl galactosaminidase, alpha, [RH, Score=347, Expect=2e-116]} {Dmel: FBgn0034117, CG7997, [RH, Score=363, Expect=1e-122]} {Celegans: WBGene00011095, gana-1, GAlactosidase/N-Acetylgalactosaminidase, [RH, Score=313, Expect=8e-103]} {Smed: dd_Smed_v6_606_0_2, dd_Smed_v6_606_0_2, [RH, Score=377, Expect=4e-128]} {RNA1509_10858, RNA1509_4952} {RNA1310_15758.1, RNA1509_10858, RNA1509_4952} {RNA1509_10858, RNA1509_4952, RNA815_6215.1} |
11. | MligTC455_20295 | 4868 | 101.42 | Mlig455_009806, Mlig455_010373 | Neo: Int S/G2/M |
PNO1 | 0.959 | - | - | - | 0.959 | - | - | Mlig455_009806 {REF} {Length: 3596} {TRANSSPLICED} {Pfam: KH domain [PF00013.31, score=20.2]} {Human: ENSG00000115946, PNO1, partner of NOB1 homolog, [RH, Score=206, Expect=4e-66]} {Mouse: ENSMUSG00000020116, Pno1, partner of NOB1 homolog, [RH, Score=207, Expect=5e-67]} {Dmel: FBgn0027334, l(1)G0004, lethal (1) G0004, [RH, Score=214, Expect=1e-69]} {Celegans: WBGene00013144, Y53C12B.2, RNA-binding protein pno-1, [RH, Score=201, Expect=2e-64]} {Smed: dd_Smed_v6_1077_0_1, dd_Smed_v6_1077_0_1, [RH, Score=131, Expect=3e-38]} {RNA1509_6066, RNA1509_8823} {RNA1310_27467, RNA1509_8823} {RNA1509_8823, RNA815_20932} Mlig455_010373 {REF} {Length: 3951} {TRANSSPLICED} {Pfam: KH domain [PF00013.31, score=18.8]} {Human: ENSG00000115946, PNO1, partner of NOB1 homolog, [RH, Score=206, Expect=3e-66]} {Mouse: ENSMUSG00000020116, Pno1, partner of NOB1 homolog, [RH, Score=207, Expect=5e-67]} {Dmel: FBgn0027334, l(1)G0004, lethal (1) G0004, [RH, Score=213, Expect=1e-69]} {Celegans: WBGene00013144, Y53C12B.2, RNA-binding protein pno-1, [RH, Score=201, Expect=2e-64]} {Smed: dd_Smed_v6_1077_0_1, dd_Smed_v6_1077_0_1, [RH, Score=129, Expect=2e-37]} {RNA1509_46964, RNA1509_6066} {RNA1310_27467, RNA1509_46964, RNA1509_6066} {RNA1509_46964, RNA1509_6066, RNA815_20932} |
12. | MligTC455_22027 | 906 | 18.88 | Mlig455_009586 | Neo: - Age: - |
USP49 | 0.957 | - | - | - | 0.957 | - | - | Mlig455_009586 {REF} {Length: 4256} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=195.9]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=64.0]} {Human: ENSG00000164663, USP49, ubiquitin specific peptidase 49, [Score=278, Expect=3e-84]; ENSG00000136014, USP44, ubiquitin specific peptidase 44, [Score=273, Expect=6e-82]} {Mouse: ENSMUSG00000090115, Usp49, ubiquitin specific peptidase 49, [Score=284, Expect=2e-86]; ENSMUSG00000020020, Usp44, ubiquitin specific peptidase 44, [Score=283, Expect=6e-86]} {Dmel: FBgn0038862, Usp8, Ubiquitin specific protease 8, [Score=108, Expect=2e-25]} {Celegans: WBGene00010702, usp-33, Ubiquitin carboxyl-terminal hydrolase, [Score=94.0, Expect=8e-20]} {Smed: dd_Smed_v6_6489_0_1, dd_Smed_v6_6489_0_1, [Score=125, Expect=6e-30]} {RNA1509_12069, RNA1509_24259, RNA1509_25953, RNA1509_39809} {RNA1310_7678.1, RNA1509_12069, RNA1509_24259, RNA1509_25953, RNA1509_39809} {RNA1509_12069, RNA1509_24259, RNA1509_25953, RNA1509_39809, RNA815_3720} |
13. | MligTC455_46615 | 798 | 16.62 | Mlig455_010462 | Neo: - Age: - Region-enriched R4: 1.396/0.00876 |
DLST | 0.956 | - | - | - | 0.956 | - | - | Mlig455_010462 {REF} {Length: 3561} {Pfam: 2-oxoacid dehydrogenases acyltransferase (catalytic domain) [PF00198.25, score=253.1]; Biotin-requiring enzyme [PF00364.24, score=66.2]} {Human: ENSG00000119689, DLST, dihydrolipoamide S-succinyltransferase, [RH, Score=475, Expect=1e-165]} {Mouse: ENSMUSG00000004789, Dlst, dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex), [RH, Score=471, Expect=5e-164]} {Dmel: FBgn0037891, CG5214, [RH, Score=363, Expect=1e-121]} {Celegans: WBGene00020950, dlst-1, DihydroLipoamide S-SuccinylTransferase, [RH, Score=471, Expect=4e-164]} {Smed: dd_Smed_v6_1456_0_1, dd_Smed_v6_1456_0_1, [RH, Score=460, Expect=2e-160]} {RNA1509_11693, RNA1509_19368, RNA1509_28903, RNA1509_42953} {RNA1310_127, RNA1509_11693, RNA1509_19368, RNA1509_28903, RNA1509_42953} {RNA1509_11693, RNA1509_19368, RNA1509_28903, RNA1509_42953, RNA815_3576} |
14. | MligTC455_16295 | 2346 | 48.87 | Mlig455_057293, Mlig455_059607 | Neo: - Age: - |
AIFM1 | 0.954 | - | - | - | 0.954 | - | - | Mlig455_057293 {REF} {Length: 2675} {TRANSSPLICED} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=157.7]; Apoptosis-inducing factor, mitochondrion-associated, C-term [PF14721.8, score=60.2]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=38.6]; Lycopene cyclase protein [PF05834.14, score=20.0]; FAD-NAD(P)-binding [PF13454.8, score=18.9]} {Human: ENSG00000156709, AIFM1, apoptosis inducing factor mitochondria associated 1, [RH, Score=337, Expect=6e-106]} {Mouse: ENSMUSG00000036932, Aifm1, apoptosis-inducing factor, mitochondrion-associated 1, [RH, Score=331, Expect=1e-103]} {Dmel: FBgn0031392, AIF, Apoptosis inducing factor, [RH, Score=332, Expect=9e-103]} {Celegans: WBGene00006937, wah-1, Worm AIF (Apoptosis inducing factor) Homolog, [RH, Score=258, Expect=8e-76]} {Smed: dd_Smed_v6_6836_0_1, dd_Smed_v6_6836_0_1, [RH, Score=376, Expect=6e-120]} {RNA1509_3709} {RNA1310_6839, RNA1509_3709} {RNA1509_3709, RNA815_3243} Mlig455_059607 {REF} {Length: 2660} {TRANSSPLICED} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=157.8]; Apoptosis-inducing factor, mitochondrion-associated, C-term [PF14721.8, score=60.0]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=38.6]; Lycopene cyclase protein [PF05834.14, score=19.9]; FAD-NAD(P)-binding [PF13454.8, score=18.7]} {Human: ENSG00000156709, AIFM1, apoptosis inducing factor mitochondria associated 1, [RH, Score=337, Expect=7e-106]} {Mouse: ENSMUSG00000036932, Aifm1, apoptosis-inducing factor, mitochondrion-associated 1, [RH, Score=330, Expect=2e-103]} {Dmel: FBgn0031392, AIF, Apoptosis inducing factor, [RH, Score=332, Expect=9e-103]} {Celegans: WBGene00006937, wah-1, Worm AIF (Apoptosis inducing factor) Homolog, [RH, Score=258, Expect=7e-76]} {Smed: dd_Smed_v6_6836_0_1, dd_Smed_v6_6836_0_1, [RH, Score=377, Expect=2e-120]} {RNA1509_3709, RNA1509_52432} {RNA1310_6839, RNA1509_52432} {RNA1509_52432, RNA815_3243} |