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Results for MligTC455_41773

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_41773 342 7.12 Mlig455_033729

Neo: -

Age: logFC(26M/2M)=-0.405

Region-enriched R4: 2.782/0.01934

Regeneration-upregulated BL: 2.334

Regeneration-enriched BL: 2.334

RAB10 Mlig455_033729 {REF} {Length: 1706} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=216.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=120.4]; ADP-ribosylation factor family [PF00025.23, score=63.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=29.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; RsgA GTPase [PF03193.18, score=23.0]; 50S ribosome-binding GTPase [PF01926.25, score=18.9]} {Human: ENSG00000084733, RAB10, RAB10, member RAS oncogene family, [Score=259, Expect=2e-88]} {Mouse: ENSMUSG00000020671, Rab10, RAB10, member RAS oncogene family, [Score=259, Expect=1e-88]} {Dmel: FBgn0015789, Rab10, [Score=246, Expect=2e-83]} {Celegans: WBGene00004273, rab-10, Ras-related protein Rab-10, [Score=244, Expect=1e-82]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=224, Expect=1e-74]} {RNA1509_59464} {RNA1310_45042} {RNA815_22097}

Cumulative graph for MligTC455_41773

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -4.446 3.273 0.37318 1.00000
RegionR2 0.389 3.273 0.67538 1.00000
RegionR3 1.11 3.273 0.16535 0.68708
RegionR4 2.782 3.273 0.00222 0.01934
RegionR5 0.892 3.273 0.29445 0.62759
RegionR6 0.528 3.273 0.56657 1.00000
RegionR7 -1.618 3.273 0.99730 1.00000
RegionR8 0.363 3.273 0.71465 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.476 3.273 1.00000 1.00000
RegenerationR2 0.004 3.273 0.99372 1.00000
RegenerationR3 -0.873 3.273 0.11870 0.53655
RegenerationR4 -0.602 3.273 0.34526 0.77630
RegenerationR5 -0.403 3.273 0.46879 0.84132
RegenerationR6 -1.057 3.273 0.10666 0.40446
RegenerationBL 2.334 3.273 0.00026 0.00900 Specific for BL: 2.334
RegenerationTP 0.843 3.273 0.32659 0.77134


Genes with expression patterns similar to MligTC455_41773

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_41773 342 7.12 Mlig455_033729

Neo: -

Age: logFC(26M/2M)=-0.405

Region-enriched R4: 2.782/0.01934

Regeneration-upregulated BL: 2.334

Regeneration-enriched BL: 2.334

RAB10 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_033729 {REF} {Length: 1706} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=216.2]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=120.4]; ADP-ribosylation factor family [PF00025.23, score=63.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=29.4]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.8]; RsgA GTPase [PF03193.18, score=23.0]; 50S ribosome-binding GTPase [PF01926.25, score=18.9]} {Human: ENSG00000084733, RAB10, RAB10, member RAS oncogene family, [Score=259, Expect=2e-88]} {Mouse: ENSMUSG00000020671, Rab10, RAB10, member RAS oncogene family, [Score=259, Expect=1e-88]} {Dmel: FBgn0015789, Rab10, [Score=246, Expect=2e-83]} {Celegans: WBGene00004273, rab-10, Ras-related protein Rab-10, [Score=244, Expect=1e-82]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [Score=224, Expect=1e-74]} {RNA1509_59464} {RNA1310_45042} {RNA815_22097}
2. MligTC455_04939 395 8.23 Mlig455_004466

Neo: -

Age: Down-Up-Down

CDKL1 2.654 - 0.877 - - 0.959 0.818 Mlig455_004466 {REF} {Length: 4238} {Pfam: Protein kinase domain [PF00069.27, score=246.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=120.7]; ABC1 atypical kinase-like domain [PF03109.18, score=19.0]; RIO1 family [PF01163.24, score=18.4]; Haspin like kinase domain [PF12330.10, score=17.8]} {Human: ENSG00000100490, CDKL1, cyclin dependent kinase like 1, [RH, Score=423, Expect=2e-147]; ENSG00000205111, CDKL4, cyclin dependent kinase like 4, [RH, Score=416, Expect=3e-144]} {Mouse: ENSMUSG00000020990, Cdkl1, cyclin-dependent kinase-like 1 (CDC2-related kinase), [RH, Score=423, Expect=7e-148]} {Dmel: FBgn0031730, CG7236, [RH, Score=379, Expect=3e-129]} {Celegans: WBGene00012779, cdkl-1, Cyclin-Dependent Kinase-Like, [Score=375, Expect=2e-128]} {Smed: dd_Smed_v6_9353_0_1, dd_Smed_v6_9353_0_1, [RH, Score=471, Expect=1e-166]} {RNA1509_9935} {RNA1310_3805.1} {RNA815_2206}
3. MligTC455_41048 764 15.92 Mlig455_045087

Neo: -

Age: logFC(26M/2M)=-0.302

TBX2 2.413 - - - 0.707 0.961 0.745 Mlig455_045087 {REF} {Length: 2264} {Pfam: T-box [PF00907.24, score=261.7]} {Human: ENSG00000121068, TBX2, T-box 2, [Score=321, Expect=3e-101]; ENSG00000135111, TBX3, T-box 3, [Score=317, Expect=3e-99]} {Mouse: ENSMUSG00000018604, Tbx3, T-box 3, [Score=325, Expect=7e-103]; ENSMUSG00000000093, Tbx2, T-box 2, [Score=320, Expect=6e-101]} {Dmel: FBgn0000179, bi, bifid, [Score=320, Expect=8e-99]} {Celegans: WBGene00006543, tbx-2, T-box protein 2, [Score=288, Expect=2e-92]} {Smed: dd_Smed_v6_11693_0_1, dd_Smed_v6_11693_0_1, [Score=322, Expect=8e-103]} {RNA1509_19743, RNA1509_48603} {RNA1310_24036, RNA1509_19743, RNA1509_48603} {RNA1509_19743, RNA1509_48603, RNA815_18470}
4. MligTC455_53909 765 15.95 Mlig455_034369

Neo: -

Age: -

Regeneration-upregulated BL: 3.468

Regeneration-enriched BL: 3.468

SBSN 1.694 - - - 0.737 0.957 - Mlig455_034369 {REF} {Length: 2517} {Pfam: Apolipoprotein A1/A4/E domain [PF01442.20, score=20.1]} {Human: ENSG00000189001, SBSN, suprabasin, [Score=81.6, Expect=1e-15]} {Mouse: ENSMUSG00000040838, Gm11639, predicted gene 11639, [Score=71.2, Expect=2e-12]} {Celegans: WBGene00001113, dur-1, Dauer Up-Regulated, [Score=120, Expect=3e-28]} {RNA1509_53891} {RNA1310_42336} {RNA815_24531}
5. MligTC455_33607 482 10.03 Mlig455_064683

Neo: Int S/G2/M

Age: -

KDM1A 1.675 - - - 0.703 0.972 - Mlig455_064683 {REF} {Length: 3352} {TRANSSPLICED} {Pfam: Flavin containing amine oxidoreductase [PF01593.26, score=195.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=57.8]; FAD dependent oxidoreductase [PF01266.26, score=30.1]; Thi4 family [PF01946.19, score=29.4]; FAD binding domain [PF00890.26, score=28.9]; FAD binding domain [PF01494.21, score=25.0]; FAD dependent oxidoreductase [PF12831.9, score=23.6]; HI0933-like protein [PF03486.16, score=21.0]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=20.5]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=20.1]} {Human: ENSG00000004487, KDM1A, lysine demethylase 1A, [Score=114, Expect=9e-26]} {Mouse: ENSMUSG00000036940, Kdm1a, lysine (K)-specific demethylase 1A, [Score=115, Expect=5e-26]} {Dmel: FBgn0260397, Su(var)3-3, Suppressor of variegation 3-3, [Score=97.8, Expect=1e-20]} {Celegans: WBGene00000137, amx-1, Amine oxidase family member 1, [Score=106, Expect=1e-23]} {Smed: dd_Smed_v6_10899_0_1, dd_Smed_v6_10899_0_1, [RH, Score=415, Expect=1e-136]} {RNA1509_26570} {RNA1310_9348} {RNA815_2019}
6. MligTC455_12775 11 0.23 Mlig455_004805

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_004805 {REF} {Length: 996} {NoTransDecoderORF} {RNA1310_49194}
7. MligTC455_41957 50 1.04 Mlig455_045094

Neo: -

Age: -

0.966 - - - - 0.966 - Mlig455_045094 {REF} {Length: 716} {NoTransDecoderORF} {RNA1310_81641}
8. MligTC455_14964 22 0.46 Mlig455_029327

Neo: -

Age: -

0.964 - - - - 0.964 - Mlig455_029327 {REF} {Length: 2017} {NoTransDecoderORF} {RNA1509_14659, RNA1509_45055} {RNA1310_2938.1, RNA1509_45055} {RNA1509_45055, RNA815_14343.1}
9. MligTC455_35373 50 1.03 Mlig455_065912, Mlig455_070019

Neo: -

Age: Down-Up-Down

Regeneration-upregulated BL: 7.651

Regeneration-enriched BL: 7.651

GLRA2 0.964 - - - - 0.964 -

Mlig455_065912 {REF} {Length: 3290} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=121.2]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=327, Expect=1e-106]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=321, Expect=2e-104]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=319, Expect=1e-103]} {Mouse: ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=325, Expect=4e-106]; ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=323, Expect=3e-105]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=317, Expect=3e-103]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=313, Expect=2e-101]} {Dmel: FBgn0024963, GluClalpha, [Score=291, Expect=5e-93]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [RH, Score=249, Expect=2e-76]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=283, Expect=3e-90]} {RNA1509_32923} {RNA1310_14629.1} {RNA815_27491}

Mlig455_070019 {REF} {Length: 4890} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=157.1]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=120.3]} {Human: ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=326, Expect=2e-106]; ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=323, Expect=4e-105]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=318, Expect=2e-103]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=325, Expect=5e-106]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=324, Expect=7e-106]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=317, Expect=6e-103]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=313, Expect=1e-101]} {Dmel: FBgn0024963, GluClalpha, [Score=288, Expect=7e-92]} {Celegans: WBGene00001587, ggr-2, GABA/Glycine Receptor family (See gbr), [RH, Score=249, Expect=2e-76]} {Smed: dd_Smed_v6_15331_0_1, dd_Smed_v6_15331_0_1, [Score=284, Expect=2e-90]} {RNA1509_32923} {RNA1310_14629.1} {RNA815_27491}
10. MligTC455_27881 54 1.12 Mlig455_062466

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.512

0.962 - - - - 0.962 - Mlig455_062466 {REF} {Length: 5589} {Pfam: Mab-21 protein [PF03281.16, score=30.3]} {RNA1509_26004} {RNA1310_3906.1} {RNA815_1664.1}
11. MligTC455_37698 9576 199.51 Mlig455_012338

Neo: -

Age: -

Regeneration-upregulated BL: 2.741

Regeneration-enriched BL: 2.741

HMCN2 0.96 - - - - 0.960 - Mlig455_012338 {REF} {Length: 7183} {Pfam: von Willebrand factor type A domain [PF13519.8, score=235.7]; von Willebrand factor type A domain [PF13768.8, score=127.1]; Protein of unknown function (DUF1638) [PF07796.13, score=56.4]; VWA domain containing CoxE-like protein [PF05762.16, score=54.0]; NTPase [PF03266.17, score=32.1]; Colicin Ia [PF11504.10, score=29.0]; Tetrahydromethanopterin S-methyltransferase, subunit A [PF04208.16, score=27.9]; Family of unknown function (DUF5347) [PF17282.4, score=25.0]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=73.6, Expect=3e-12]; ENSG00000143341, HMCN1, hemicentin 1, [Score=72.0, Expect=1e-11]} {Mouse: ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=73.2, Expect=3e-12]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=72.4, Expect=7e-12]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=93.2, Expect=1e-18]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=92.4, Expect=2e-18]} {RNA1509_415} {RNA1310_3126.1} {RNA815_1151.1}
12. MligTC455_37699 9492 197.74 Mlig455_034962

Neo: -

Age: -

Regeneration-upregulated BL: 2.634

Regeneration-enriched BL: 2.634

HMCN2 0.96 - - - - 0.960 - Mlig455_034962 {REF} {Length: 5538} {Pfam: von Willebrand factor type A domain [PF13519.8, score=200.3]; von Willebrand factor type A domain [PF13768.8, score=108.6]; Protein of unknown function (DUF1638) [PF07796.13, score=47.0]; VWA domain containing CoxE-like protein [PF05762.16, score=46.2]; NTPase [PF03266.17, score=26.8]; Colicin Ia [PF11504.10, score=25.5]; Family of unknown function (DUF5347) [PF17282.4, score=20.6]} {Human: ENSG00000148357, HMCN2, hemicentin 2, [Score=73.2, Expect=4e-12]; ENSG00000143341, HMCN1, hemicentin 1, [Score=71.6, Expect=1e-11]} {Mouse: ENSMUSG00000055632, Hmcn2, hemicentin 2, [Score=73.6, Expect=2e-12]; ENSMUSG00000066842, Hmcn1, hemicentin 1, [Score=72.0, Expect=7e-12]} {Celegans: WBGene00001863, him-4, Hemicentin; High Incidence of Males (Increased X chromosome loss), [Score=93.2, Expect=1e-18]} {Smed: dd_Smed_v6_1161_0_1, dd_Smed_v6_1161_0_1, [Score=92.8, Expect=1e-18]} {RNA1509_415, RNA1509_59657} {RNA1310_3126.1, RNA1509_59657} {RNA1509_59657, RNA815_1151.1}
13. MligTC455_39921 16 0.34 Mlig455_011423

Neo: -

Age: -

0.96 - - - - 0.960 - Mlig455_011423 {REF} {Length: 868} {NoTransDecoderORF} {RNA1509_46569} {RNA1310_25987} {RNA815_7475.2}
14. MligTC455_07174 94 1.96 Mlig455_007312

Neo: -

Age: Up-Down-Down

0.958 - - - - 0.958 - Mlig455_007312 {REF} {Length: 240} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56237} {RNA1310_59534.2} {RNA815_29807}
15. MligTC455_35051 220 4.58 Mlig455_020175

Neo: -

Age: Down-Up-Down

Region-enriched R8: 5.304/0.00000
Region-enriched R7: 4.092/0.00006

CALM3 0.958 - - - - 0.958 - Mlig455_020175 {REF} {Length: 927} {Pfam: EF hand [PF00036.34, score=111.3]; EF-hand domain pair [PF13499.8, score=98.6]; EF-hand domain [PF13405.8, score=91.1]; EF-hand domain pair [PF13833.8, score=78.1]; EF hand [PF13202.8, score=76.7]; EF-hand domain [PF14658.8, score=56.1]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=26.7]; Dockerin type I domain [PF00404.20, score=22.0]; EF-hand domain [PF17959.3, score=21.1]} {Human: ENSG00000160014, CALM3, calmodulin 3, [Score=146, Expect=5e-45]; ENSG00000198668, CALM1, calmodulin 1, [Score=146, Expect=5e-45]; ENSG00000143933, CALM2, calmodulin 2, [Score=146, Expect=5e-45]; ENSG00000178363, CALML3, calmodulin like 3, [Score=143, Expect=8e-44]} {Mouse: ENSMUSG00000001175, Calm1, calmodulin 1, [Score=146, Expect=3e-45]; ENSMUSG00000036438, Calm2, calmodulin 2, [Score=146, Expect=3e-45]; ENSMUSG00000019370, Calm3, calmodulin 3, [Score=146, Expect=3e-45]; ENSMUSG00000063130, Calml3, calmodulin-like 3, [Score=144, Expect=4e-44]} {Dmel: FBgn0000253, Cam, Calmodulin, [Score=148, Expect=8e-46]} {Celegans: WBGene00000552, cmd-1, Calmodulin, [Score=147, Expect=7e-46]} {Smed: dd_Smed_v6_255_0_1, dd_Smed_v6_255_0_1, [Score=147, Expect=5e-46]} {RNA1310_46966} {RNA815_26674}
16. MligTC455_32973 42 0.88 Mlig455_048857

Neo: -

Age: -

KCTD1 0.952 - - - - 0.952 - Mlig455_048857 {REF} {Length: 2446} {Pfam: Domain of unknown function (DUF3504) [PF12012.10, score=41.7]; Phage integrase family [PF00589.24, score=30.2]} {Human: ENSG00000134504, KCTD1, potassium channel tetramerization domain containing 1, [Score=98.2, Expect=3e-21]} {Mouse: ENSMUSG00000036225, Kctd1, potassium channel tetramerisation domain containing 1, [Score=98.2, Expect=2e-21]} {RNA1509_32880} {RNA1310_39104} {RNA815_16657.2}
17. MligTC455_19844 270 5.62 Mlig455_068340

Neo: -

Age: -

0.951 - - - - 0.951 - Mlig455_068340 {REF} {Length: 348} {TRANSSPLICED} {Pfam: PET assembly of cytochrome c oxidase, mitochondrial [PF15786.7, score=45.7]} {RNA1509_28703} {RNA1310_21339} {RNA815_12138.1}
18. MligTC455_45522 524 10.92 Mlig455_024216

Neo: -

Age: -

SH3GLB1 0.951 - - - - - 0.951 Mlig455_024216 {REF} {Length: 2196} {Pfam: BAR domain [PF03114.20, score=213.0]; BAR domain of APPL family [PF16746.7, score=30.8]; Bin/amphiphysin/Rvs domain for vesicular trafficking [PF10455.11, score=29.7]} {Human: ENSG00000097033, SH3GLB1, SH3 domain containing GRB2 like, endophilin B1, [RH, Score=264, Expect=4e-87]} {Mouse: ENSMUSG00000037062, Sh3glb1, SH3-domain GRB2-like B1 (endophilin), [RH, Score=265, Expect=7e-88]} {Dmel: FBgn0034433, EndoB, Endophilin B, [RH, Score=231, Expect=2e-74]} {Celegans: WBGene00001335, F35A5.8, Endophilin-Related Protein, [RH, Score=227, Expect=3e-73]} {Smed: dd_Smed_v6_1387_0_2, dd_Smed_v6_1387_0_2, [RH, Score=199, Expect=6e-64]} {RNA1509_34163, RNA1509_37386, RNA1509_43220, RNA1509_55485} {RNA1310_19399, RNA1509_34163, RNA1509_37386, RNA1509_43220, RNA1509_55485} {RNA1509_34163, RNA1509_37386, RNA1509_43220, RNA1509_55485, RNA815_8016.2}

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