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Results for MligTC455_42475

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_42475 2357 49.11 Mlig455_034933

Neo: -

Age: -

Mlig455_034933 {REF} {Length: 1948} {Smed: dd_Smed_v6_6979_0_1, dd_Smed_v6_6979_0_1, [RH, Score=49.7, Expect=2e-07]} {RNA1509_16213, RNA1509_2544} {RNA1310_12361.2, RNA1509_16213, RNA1509_2544} {RNA1509_16213, RNA1509_2544, RNA815_4094.1}

Cumulative graph for MligTC455_42475

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.643 5.713 0.28137 0.93219
RegionR2 -0.694 5.713 0.07594 0.33703
RegionR3 -0.022 5.713 0.94522 1.00000
RegionR4 0.517 5.713 0.16163 0.41989
RegionR5 -0.367 5.713 0.25102 0.56739
RegionR6 -0.112 5.713 0.73061 1.00000
RegionR7 0.343 5.713 0.31721 0.95237
RegionR8 -0.308 5.713 0.48365 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -1.863 5.713 0.04140 0.67581
RegenerationR2 0.294 5.713 0.44406 0.84243
RegenerationR3 -0.573 5.713 0.15172 0.58105
RegenerationR4 -0.706 5.713 0.08538 0.46099
RegenerationR5 -0.536 5.713 0.18098 0.61103
RegenerationR6 -0.687 5.713 0.09778 0.38911
RegenerationBL -0.898 5.713 0.02878 0.18845
RegenerationTP -0.621 5.713 0.14634 0.56955


Genes with expression patterns similar to MligTC455_42475

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_42475 2357 49.11 Mlig455_034933

Neo: -

Age: -

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_034933 {REF} {Length: 1948} {Smed: dd_Smed_v6_6979_0_1, dd_Smed_v6_6979_0_1, [RH, Score=49.7, Expect=2e-07]} {RNA1509_16213, RNA1509_2544} {RNA1310_12361.2, RNA1509_16213, RNA1509_2544} {RNA1509_16213, RNA1509_2544, RNA815_4094.1}
2. MligTC455_45885 2359 49.14 Mlig455_006950, Mlig455_017967

Neo: -

Age: logFC(26M/2M)=-0.281

DRC1 1.813 - - - - 0.967 0.846

Mlig455_006950 {REF} {Length: 3079} {Pfam: Sperm tail [PF14772.8, score=101.6]; Sperm tail C-terminal domain [PF14775.8, score=76.2]} {Human: ENSG00000157856, DRC1, dynein regulatory complex subunit 1, [RH, Score=516, Expect=1e-173]} {Mouse: ENSMUSG00000073102, Drc1, dynein regulatory complex subunit 1, [RH, Score=558, Expect=0.0]} {Dmel: FBgn0030004, CG10958, [RH, Score=209, Expect=9e-58]} {Smed: dd_Smed_v6_8761_0_1, dd_Smed_v6_8761_0_1, [RH, Score=662, Expect=0.0]} {RNA1509_27442, RNA1509_6366} {RNA1310_8469.1, RNA1509_27442, RNA1509_6366} {RNA1509_27442, RNA1509_6366, RNA815_3242}

Mlig455_017967 {REF} {Length: 2611} {Pfam: Sperm tail [PF14772.8, score=101.6]; Sperm tail C-terminal domain [PF14775.8, score=76.2]} {Human: ENSG00000157856, DRC1, dynein regulatory complex subunit 1, [RH, Score=516, Expect=1e-173]} {Mouse: ENSMUSG00000073102, Drc1, dynein regulatory complex subunit 1, [RH, Score=556, Expect=0.0]} {Dmel: FBgn0030004, CG10958, [RH, Score=209, Expect=1e-57]} {Smed: dd_Smed_v6_8761_0_1, dd_Smed_v6_8761_0_1, [RH, Score=662, Expect=0.0]} {RNA1509_6366, RNA1509_8386} {RNA1310_8469.1, RNA1509_8386} {RNA1509_8386, RNA815_3242}
3. MligTC455_40157 601 12.52 Mlig455_011008

Neo: -

Age: -

ZMYND12 1.806 - - - - 0.952 0.854 Mlig455_011008 {REF} {Length: 2345} {Pfam: MYND finger [PF01753.20, score=36.1]; MalT-like TPR region [PF17874.3, score=22.6]; Tetratricopeptide repeat [PF07719.19, score=22.5]; Tetratricopeptide repeat [PF00515.30, score=21.0]; Tetratricopeptide repeat [PF13424.8, score=21.0]} {Human: ENSG00000066185, ZMYND12, zinc finger MYND-type containing 12, [RH, Score=286, Expect=1e-93]} {Mouse: ENSMUSG00000070806, Zmynd12, zinc finger, MYND domain containing 12, [RH, Score=297, Expect=4e-98]} {Smed: dd_Smed_v6_10079_0_1, dd_Smed_v6_10079_0_1, [RH, Score=393, Expect=4e-136]} {RNA1509_3913} {RNA1310_12452} {RNA815_3855}
4. MligTC455_32309 828 17.24 Mlig455_050857

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.573

ZAN 1.785 - - - - 0.974 0.811 Mlig455_050857 {REF} {Length: 9674} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=57.8, Expect=5e-07]} {RNA1509_20499, RNA1509_31314, RNA1509_37922, RNA1509_38195, RNA1509_458, RNA1509_7032} {RNA1310_3777.1, RNA1509_20499, RNA1509_31314, RNA1509_37922, RNA1509_38195, RNA1509_7032} {RNA1509_20499, RNA1509_31314, RNA1509_37922, RNA1509_38195, RNA1509_7032, RNA815_49.1}
5. MligTC455_37361 5370 111.88 Mlig455_043035

Neo: -

Age: logFC(26M/2M)=-0.378

CFAP52 1.778 - - - - 0.960 0.818 Mlig455_043035 {REF} {Length: 2490} {Pfam: WD domain, G-beta repeat [PF00400.34, score=123.9]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=42.1]; WD40-like domain [PF17005.7, score=27.1]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=757, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=441, Expect=1e-145]} {Celegans: WBGene00004895, smu-1, SMU-1; Suppressor of Mec and Unc defects, [Score=60.5, Expect=2e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=841, Expect=0.0]} {RNA1509_1341} {RNA1310_8859, RNA1509_1341} {RNA1509_1341, RNA815_2855}
6. MligTC455_37360 5178 107.87 Mlig455_043000

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.956

CFAP52 1.753 - - - - 0.960 0.793 Mlig455_043000 {REF} {Length: 2520} {Pfam: WD domain, G-beta repeat [PF00400.34, score=124.0]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=41.8]; WD40-like domain [PF17005.7, score=26.5]} {Human: ENSG00000166596, CFAP52, cilia and flagella associated protein 52, [RH, Score=748, Expect=0.0]} {Mouse: ENSMUSG00000020904, Cfap52, cilia and flagella associated protein 52, [RH, Score=756, Expect=0.0]} {Dmel: FBgn0035724, CG10064, [RH, Score=439, Expect=3e-145]} {Celegans: WBGene00022119, copa-1, Coatomer subunit alpha, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_2585_0_1, dd_Smed_v6_2585_0_1, [RH, Score=838, Expect=0.0]} {RNA1509_1341} {RNA1310_8859} {RNA815_2855}
7. MligTC455_49596 1668 34.74 Mlig455_063375

Neo: -

Age: logFC(26M/2M)=-0.423

Region-enriched R2: 1.067/0.02988

ARMC4 1.737 - - - - 0.953 0.784 Mlig455_063375 {REF} {Length: 3432} {TRANSSPLICED} {Pfam: Armadillo/beta-catenin-like repeat [PF00514.25, score=192.9]; HEAT repeats [PF13646.8, score=53.0]; Armadillo-like [PF04826.15, score=26.7]; V-ATPase subunit H [PF11698.10, score=26.4]; HEAT-like repeat [PF13513.8, score=26.1]; Kinesin-associated protein (KAP) [PF05804.14, score=24.7]; V-ATPase subunit H [PF03224.16, score=23.0]; non-SMC mitotic condensation complex subunit 1 [PF12717.9, score=22.2]; HEAT repeat [PF02985.24, score=19.6]} {Human: ENSG00000169126, ARMC4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Mouse: ENSMUSG00000061802, Armc4, armadillo repeat containing 4, [RH, Score=942, Expect=0.0]} {Dmel: FBgn0031905, gudu, [RH, Score=592, Expect=0.0]} {Smed: dd_Smed_v6_5065_0_1, dd_Smed_v6_5065_0_1, [RH, Score=932, Expect=0.0]} {RNA1509_1009, RNA1509_21601} {RNA1310_2954.1, RNA1509_1009, RNA1509_21601} {RNA1509_1009, RNA1509_21601, RNA815_1045}
8. MligTC455_41151 536 11.16 Mlig455_007760

Neo: -

Age: -

PNKP 1.732 0.769 - - - 0.963 - Mlig455_007760 {REF} {Length: 1965} {TRANSSPLICED} {Pfam: Polynucleotide kinase 3 phosphatase [PF08645.13, score=165.7]; AAA domain [PF13671.8, score=55.5]; Zeta toxin [PF06414.14, score=20.7]} {Human: ENSG00000039650, PNKP, polynucleotide kinase 3'-phosphatase, [Score=259, Expect=8e-81]} {Mouse: ENSMUSG00000002963, Pnkp, polynucleotide kinase 3'- phosphatase, [Score=244, Expect=4e-75]} {Dmel: FBgn0037578, CG9601, [Score=231, Expect=2e-70]} {Celegans: WBGene00009010, F21D5.5, [Score=254, Expect=2e-80]} {Smed: dd_Smed_v6_1211_0_2, dd_Smed_v6_1211_0_2, [Score=216, Expect=2e-65]} {RNA1509_19728, RNA1509_46985} {RNA1310_14048, RNA1509_19728, RNA1509_46985} {RNA1509_19728, RNA1509_46985, RNA815_7193.1}
9. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

MX2 1.708 - - - - 0.961 0.747 Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
10. MligTC455_46851 507 10.56 Mlig455_059440

Neo: -

Age: logFC(26M/2M)=-0.309

1.685 - - - - 0.954 0.731 Mlig455_059440 {REF} {Length: 3521} {TRANSSPLICED} {Pfam: Coiled-coil domain-containing protein 158 [PF15921.7, score=48.5]} {Mouse: ENSMUSG00000050050, Ccdc158, coiled-coil domain containing 158, [RH, Score=85.5, Expect=2e-16]} {Smed: dd_Smed_v6_10831_0_1, dd_Smed_v6_10831_0_1, [RH, Score=72.8, Expect=7e-13]} {RNA1509_28804, RNA1509_7522} {RNA1310_3662, RNA1509_28804} {RNA1509_28804, RNA815_5689}
11. MligTC455_47575 203 4.23 Mlig455_068827

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-1.457

MAN1C1 1.674 - 0.711 - - 0.963 - Mlig455_068827 {REF} {Length: 3468} {Pfam: Glycosyl hydrolase family 47 [PF01532.22, score=378.5]} {Human: ENSG00000117643, MAN1C1, mannosidase alpha class 1C member 1, [Score=268, Expect=7e-82]; ENSG00000198162, MAN1A2, mannosidase alpha class 1A member 2, [Score=268, Expect=2e-81]} {Mouse: ENSMUSG00000037306, Man1c1, mannosidase, alpha, class 1C, member 1, [Score=267, Expect=2e-81]; ENSMUSG00000008763, Man1a2, mannosidase, alpha, class 1A, member 2, [Score=267, Expect=2e-81]; ENSMUSG00000003746, Man1a, mannosidase 1, alpha, [Score=264, Expect=6e-80]} {Dmel: FBgn0259170, alpha-Man-Ia, alpha-Mannosidase class I a, [Score=268, Expect=1e-81]} {Celegans: WBGene00008258, mans-2, Mannosyl-oligosaccharide 1,2-alpha-mannosidase C52E4.5, [Score=250, Expect=1e-75]} {Smed: dd_Smed_v6_6801_0_1, dd_Smed_v6_6801_0_1, [Score=267, Expect=3e-82]} {RNA1509_48511, RNA1509_9530} {RNA1310_9474.1, RNA1509_48511, RNA1509_9530} {RNA1509_48511, RNA1509_9530, RNA815_6962}
12. MligTC455_18479 293 6.11 Mlig455_029348

Neo: -

Age: -

Region-enriched R2: 2.256/0.00988

0.984 - - - - 0.984 - Mlig455_029348 {REF} {Length: 2771} {Pfam: Leucine Rich repeat [PF13516.8, score=43.0]} {Mouse: ENSMUSG00000099564, Gm28729, predicted gene 28729, [RH, Score=125, Expect=4e-31]} {Smed: dd_Smed_v6_16437_0_1, dd_Smed_v6_16437_0_1, [RH, Score=268, Expect=2e-84]} {RNA1509_18255, RNA1509_55057} {RNA1310_16954, RNA1509_18255, RNA1509_55057} {RNA1509_18255, RNA1509_55057, RNA815_6360}
13. MligTC455_16412 403 8.39 Mlig455_048929, Mlig455_048953

Neo: -

Age: Down-Up-Up

MAP3K2 0.983 - - - - 0.983 -

Mlig455_048929 {REF} {Length: 2311} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=216.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=149.9]; Kinase-like [PF14531.8, score=28.8]; Fungal protein kinase [PF17667.3, score=20.0]; ABC1 atypical kinase-like domain [PF03109.18, score=18.7]} {Human: ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [Score=238, Expect=3e-71]; ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=234, Expect=3e-69]} {Mouse: ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [Score=241, Expect=2e-72]; ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=233, Expect=3e-69]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=161, Expect=3e-42]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=167, Expect=3e-45]} {Smed: dd_Smed_v6_6304_0_1, dd_Smed_v6_6304_0_1, [RH, Score=177, Expect=2e-52]} {RNA1509_12704} {RNA1310_14266} {RNA815_4624.1}

Mlig455_048953 {REF} {Length: 2666} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=217.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=150.2]; Kinase-like [PF14531.8, score=30.6]; Fungal protein kinase [PF17667.3, score=20.1]; ABC1 atypical kinase-like domain [PF03109.18, score=19.0]} {Human: ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [Score=238, Expect=2e-71]; ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [Score=233, Expect=1e-69]} {Mouse: ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [Score=241, Expect=8e-73]; ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [Score=232, Expect=2e-69]} {Dmel: FBgn0014006, Ask1, Apoptotic signal-regulating kinase 1, [Score=162, Expect=1e-42]} {Celegans: WBGene00003822, nsy-1, Mitogen-activated protein kinase kinase kinase nsy-1, [Score=169, Expect=2e-45]} {Smed: dd_Smed_v6_6304_0_1, dd_Smed_v6_6304_0_1, [RH, Score=177, Expect=9e-53]} {RNA1509_12704} {RNA1310_14266} {RNA815_4624.1}
14. MligTC455_48507 330 6.88 Mlig455_030151

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.466

TMEM232 0.981 - - - - 0.981 - Mlig455_030151 {REF} {Length: 2337} {TRANSSPLICED} {Pfam: Transmembrane protein family 232 [PF15877.7, score=221.6]} {Human: ENSG00000186952, TMEM232, transmembrane protein 232, [Score=155, Expect=2e-39]} {Mouse: ENSMUSG00000045036, Tmem232, transmembrane protein 232, [Score=164, Expect=2e-42]} {Smed: dd_Smed_v6_15138_0_1, dd_Smed_v6_15138_0_1, [RH, Score=160, Expect=8e-42]} {RNA1509_11088} {RNA1310_8942.1} {RNA815_6522}
15. MligTC455_43616 1798 37.45 Mlig455_024513

Neo: -

Age: logFC(26M/2M)=-0.338

Region-enriched R2: 1.066/0.02738

CFAP57 0.979 - - - - 0.979 - Mlig455_024513 {REF} {Length: 5805} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=65.8]; Crescentin protein [PF19220.2, score=26.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=25.5]; Autophagy protein 16 (ATG16) [PF08614.13, score=24.0]; Coiled-coil region of CCDC155 or KASH [PF14662.8, score=20.0]} {Human: ENSG00000243710, CFAP57, cilia and flagella associated protein 57, [RH, Score=1363, Expect=0.0]} {Mouse: ENSMUSG00000028730, Cfap57, cilia and flagella associated protein 57, [RH, Score=1360, Expect=0.0]} {Dmel: FBgn0034745, CG4329, [RH, Score=496, Expect=5e-155]} {Celegans: WBGene00003047, lis-1, Lissencephaly-1 homolog, [Score=55.1, Expect=2e-07]} {Smed: dd_Smed_v6_3323_0_1, dd_Smed_v6_3323_0_1, [RH, Score=1620, Expect=0.0]} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA1509_836} {RNA1310_1737, RNA1509_14259, RNA1509_18569, RNA1509_42897} {RNA1509_14259, RNA1509_18569, RNA1509_42897, RNA815_558}
16. MligTC455_43627 1683 35.07 Mlig455_012966

Neo: -

Age: -

0.979 - - - - 0.979 - Mlig455_012966 {REF} {Length: 4640} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=231.1]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=2e-13]} {RNA1509_10570} {RNA1310_7155.1} {RNA815_1910.1}
17. MligTC455_31292 287 5.97 Mlig455_059964

Neo: -

Age: logFC(26M/2M)=-0.518

0.976 - - - - 0.976 - Mlig455_059964 {REF} {Length: 6272} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4549) [PF15082.8, score=142.8]; Ligand-gated ion channel [PF00060.28, score=50.1]} {Mouse: ENSMUSG00000075225, Ccdc162, coiled-coil domain containing 162, [Score=914, Expect=0.0]} {Dmel: FBgn0052704, Ir8a, Ionotropic receptor 8a, [Score=55.5, Expect=5e-07]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [Score=58.2, Expect=6e-08]} {Smed: dd_Smed_v6_16643_0_1, dd_Smed_v6_16643_0_1, [RH, Score=706, Expect=0.0]} {RNA1509_21772} {RNA1310_311.1} {RNA815_144.1}
18. MligTC455_03200 31 0.64 Mlig455_054002

Neo: -

Age: -

0.972 - - - - 0.972 - Mlig455_054002 {REF} {Length: 511} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=52.8, Expect=9e-09]} {RNA1509_8360} {RNA1310_8325.1} {RNA815_1671.1}
19. MligTC455_43971 1049 21.85 Mlig455_014401

Neo: -

Age: logFC(26M/2M)=-0.330

NEK1 0.972 - - - - 0.972 - Mlig455_014401 {REF} {Length: 2439} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=118.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=68.0]; Kinase-like [PF14531.8, score=20.7]} {Human: ENSG00000137601, NEK1, NIMA related kinase 1, [Score=111, Expect=1e-24]} {Mouse: ENSMUSG00000049897, Stkld1, serine/threonine kinase-like domain containing 1, [RH, Score=142, Expect=3e-35]} {Dmel: FBgn0029970, Nek2, [Score=68.9, Expect=8e-12]} {Celegans: WBGene00021461, nekl-1, NEK (NEver in mitosis Kinase) Like, [Score=89.4, Expect=3e-18]} {Smed: dd_Smed_v6_10144_0_2, dd_Smed_v6_10144_0_2, [Score=100, Expect=7e-22]} {RNA1509_7618} {RNA1310_9007, RNA1509_7618} {RNA1509_7618, RNA815_6823}
20. MligTC455_44462 171 3.56 Mlig455_019811

Neo: -

Age: Down-Up-Down

0.972 - - - - 0.972 - Mlig455_019811 {REF} {Length: 1980} {RNA1509_25005} {RNA1310_2380} {RNA815_20909.1}
21. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

AC254952.1 0.972 - - - - 0.972 - Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
22. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

0.971 - - - - 0.971 - Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
23. MligTC455_48348 938 19.55 Mlig455_027793, Mlig455_063494

Neo: -

Age: logFC(26M/2M)=-0.661

Region-enriched R8: 1.890/0.04247

SCN5A 0.971 - - - - 0.971 -

Mlig455_027793 {REF} {Length: 6955} {Pfam: Ion transport protein [PF00520.33, score=754.1]; Polycystin cation channel [PF08016.14, score=55.1]; ZIP Zinc transporter [PF02535.24, score=22.9]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=22.8]} {Human: ENSG00000183873, SCN5A, sodium voltage-gated channel alpha subunit 5, [RH, Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000032511, Scn5a, sodium channel, voltage-gated, type V, alpha, [Score=1260, Expect=0.0]; ENSMUSG00000001027, Scn4a, sodium channel, voltage-gated, type IV, alpha, [Score=1253, Expect=0.0]} {Dmel: FBgn0285944, para, paralytic, [Score=914, Expect=0.0]} {Celegans: WBGene00000367, cca-1, Voltage-dependent T-type calcium channel subunit alpha, [Score=452, Expect=2e-130]} {Smed: dd_Smed_v6_12243_0_1, dd_Smed_v6_12243_0_1, [RH, Score=1245, Expect=0.0]} {RNA1509_2331} {RNA1310_490.1} {RNA815_185.1}

Mlig455_063494 {REF} {Length: 7000} {Pfam: Ion transport protein [PF00520.33, score=755.0]; Polycystin cation channel [PF08016.14, score=55.6]; ZIP Zinc transporter [PF02535.24, score=23.8]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=22.8]} {Human: ENSG00000183873, SCN5A, sodium voltage-gated channel alpha subunit 5, [RH, Score=1273, Expect=0.0]} {Mouse: ENSMUSG00000032511, Scn5a, sodium channel, voltage-gated, type V, alpha, [Score=1261, Expect=0.0]; ENSMUSG00000001027, Scn4a, sodium channel, voltage-gated, type IV, alpha, [Score=1240, Expect=0.0]} {Dmel: FBgn0285944, para, paralytic, [Score=914, Expect=0.0]} {Celegans: WBGene00001187, egl-19, Voltage-dependent L-type calcium channel subunit alpha, [Score=310, Expect=8e-85]} {Smed: dd_Smed_v6_12243_0_1, dd_Smed_v6_12243_0_1, [RH, Score=1244, Expect=0.0]} {RNA1509_2331} {RNA1310_490.1, RNA1509_2331} {RNA1509_2331, RNA815_185.1}
24. MligTC455_31889 414 8.63 Mlig455_027646, Mlig455_065376

Neo: -

Age: -

0.97 - - - - 0.970 -

Mlig455_027646 {REF} {Length: 613} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=20.2]} {RNA1509_2283} {RNA1310_1293.1} {RNA815_1077}

Mlig455_065376 {REF} {Length: 615} {TRANSSPLICED} {RNA1509_37997} {RNA1310_1293.1} {RNA815_1077}
25. MligTC455_31890 210 4.38 Mlig455_070942

Neo: -

Age: logFC(26M/2M)=-0.564

0.97 - - - - 0.970 - Mlig455_070942 {REF} {Length: 2335} {Pfam: MULE transposase domain [PF10551.11, score=21.4]; Domain of unknown function (DUF4806) [PF16064.7, score=19.0]} {Smed: dd_Smed_v6_24877_0_1, dd_Smed_v6_24877_0_1, [Score=52.0, Expect=2e-08]} {RNA1509_28268} {RNA1310_1293.1} {RNA815_1077}
26. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

DST 0.968 - - - - 0.968 - Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}
27. MligTC455_32937 681 14.18 Mlig455_039443

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.822

0.968 - - - - 0.968 - Mlig455_039443 {REF} {Length: 1676} {RNA1509_14386} {RNA1310_21532, RNA1509_14386} {RNA1509_14386, RNA815_8850}
28. MligTC455_45839 1905 39.68 Mlig455_059781, Mlig455_070317

Neo: -

Age: logFC(26M/2M)=-0.483

LRRC43 0.968 - - - - 0.968 -

Mlig455_059781 {REF} {Length: 2388} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=39.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=34.8]; Leucine rich repeat [PF13855.8, score=30.9]} {Human: ENSG00000158113, LRRC43, leucine rich repeat containing 43, [RH, Score=202, Expect=2e-55]} {Mouse: ENSMUSG00000063409, Lrrc43, leucine rich repeat containing 43, [RH, Score=216, Expect=9e-61]} {Dmel: FBgn0014395, tilB, touch insensitive larva B, [Score=63.9, Expect=2e-10]} {Smed: dd_Smed_v6_12354_0_1, dd_Smed_v6_12354_0_1, [RH, Score=184, Expect=2e-50]} {RNA1509_3859} {RNA1310_9281, RNA1509_3859} {RNA1509_3859, RNA815_3282}

Mlig455_070317 {REF} {Length: 2398} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=39.0]; Leucine Rich repeats (2 copies) [PF12799.9, score=34.8]; Leucine rich repeat [PF13855.8, score=30.8]} {Human: ENSG00000158113, LRRC43, leucine rich repeat containing 43, [RH, Score=200, Expect=5e-55]} {Mouse: ENSMUSG00000063409, Lrrc43, leucine rich repeat containing 43, [RH, Score=213, Expect=1e-59]} {Dmel: FBgn0014395, tilB, touch insensitive larva B, [Score=63.9, Expect=2e-10]} {Smed: dd_Smed_v6_12354_0_1, dd_Smed_v6_12354_0_1, [RH, Score=184, Expect=2e-50]} {RNA1509_3859} {RNA1310_9281} {RNA815_3282}
29. MligTC455_30256 48 0.99 Mlig455_003751, Mlig455_053129

Neo: -

Age: logFC(26M/2M)=-2.069

0.967 - - - - 0.967 -

Mlig455_003751 {REF} {Length: 2349} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=53.4]} {Smed: dd_Smed_v6_18385_0_1, dd_Smed_v6_18385_0_1, [Score=89.0, Expect=7e-20]} {RNA1509_31144} {RNA1310_15076.1} {RNA815_5159.1}

Mlig455_053129 {REF} {Length: 2316} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=24.2]} {RNA1509_31144, RNA1509_40622} {RNA1310_15076.1, RNA1509_40622} {RNA1509_40622, RNA815_5159.1}
30. MligTC455_42975 99 2.06 Mlig455_012209

Neo: -

Age: Down-Up-Down

0.967 - - - - 0.967 - Mlig455_012209 {REF} {Length: 2730} {TRANSSPLICED} {RNA1509_25715} {RNA1310_11361, RNA1509_25715} {RNA1509_25715, RNA815_11628}
31. MligTC455_46254 1114 23.21 Mlig455_000448

Neo: -

Age: -

CASC1 0.967 - - - - 0.967 - Mlig455_000448 {REF} {Length: 3104} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=168.4]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=29.2]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=320, Expect=4e-98]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=295, Expect=2e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=83.6, Expect=4e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1, RNA1509_1842} {RNA1509_1842, RNA815_2139}
32. MligTC455_24552 1774 36.95 Mlig455_015821, Mlig455_015828

Neo: -

Age: Up-Up-Up

IQCE 0.966 - - - - 0.966 -

Mlig455_015821 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}

Mlig455_015828 {REF} {Length: 2744} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1, RNA1509_3714} {RNA1509_3714, RNA815_2091.1}
33. MligTC455_52249 1365 28.44 Mlig455_007872

Neo: -

Age: Down-Down-Up

Region-enriched R2: 1.111/0.04280

0.966 - - - - 0.966 - Mlig455_007872 {REF} {Length: 2081} {Pfam: Transmembrane protein 237 [PF15383.8, score=91.3]} {Mouse: ENSMUSG00000038079, Tmem237, transmembrane protein 237, [Score=55.1, Expect=1e-07]} {RNA1509_6211} {RNA1310_13658, RNA1509_6211} {RNA1509_6211, RNA815_1318.1}
34. MligTC455_21673 316 6.58 Mlig455_013782, Mlig455_013911

Neo: -

Age: -

0.965 - - - - 0.965 -

Mlig455_013782 {REF} {Length: 3170} {Pfam: Ras association (RalGDS/AF-6) domain [PF00788.25, score=47.1]} {Dmel: FBgn0031745, rau, [RH, Score=72.8, Expect=4e-13]} {RNA1509_28308} {RNA1310_8072} {RNA815_15473}

Mlig455_013911 {REF} {Length: 3190} {Pfam: Ras association (RalGDS/AF-6) domain [PF00788.25, score=46.0]} {Dmel: FBgn0031745, rau, [RH, Score=76.3, Expect=3e-14]} {RNA1509_28308} {RNA1310_8072, RNA1509_28308} {RNA1509_28308, RNA815_15473}
35. MligTC455_29164 899 18.73 Mlig455_006856

Neo: -

Age: Down-Up-Up

ANKRD42 0.965 - - - - 0.965 - Mlig455_006856 {REF} {Length: 2038} {TRANSSPLICED} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=124.3]; Ankyrin repeats (3 copies) [PF12796.9, score=118.0]; Ankyrin repeats (many copies) [PF13857.8, score=106.6]; Ankyrin repeat [PF13606.8, score=85.3]; Ankyrin repeat [PF00023.32, score=69.9]} {Human: ENSG00000137494, ANKRD42, ankyrin repeat domain 42, [RH, Score=493, Expect=2e-170]} {Mouse: ENSMUSG00000041343, Ankrd42, ankyrin repeat domain 42, [RH, Score=491, Expect=1e-169]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=143, Expect=1e-35]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=125, Expect=4e-30]} {Smed: dd_Smed_v6_10615_0_1, dd_Smed_v6_10615_0_1, [RH, Score=621, Expect=0.0]} {RNA1509_29991} {RNA1310_12980.1} {RNA815_2353.1}
36. MligTC455_41489 218 4.55 Mlig455_063751

Neo: -

Age: -

SLC18A3 0.965 - - - - 0.965 - Mlig455_063751 {REF} {Length: 1991} {Pfam: Major Facilitator Superfamily [PF07690.18, score=95.8]; MFS_1 like family [PF12832.9, score=26.3]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [Score=103, Expect=5e-23]; ENSG00000036565, SLC18A1, solute carrier family 18 member A1, [Score=99.4, Expect=1e-21]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [Score=107, Expect=3e-24]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [Score=199, Expect=1e-56]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [Score=182, Expect=3e-51]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [Score=187, Expect=4e-53]} {RNA1509_37669} {RNA1310_14899.1, RNA1509_37669} {RNA1509_37669, RNA815_15265}
37. MligTC455_42108 83 1.73 Mlig455_063983

Neo: -

Age: Up-Down-Down

COL6A6 0.965 - - - - 0.965 - Mlig455_063983 {REF} {Length: 6296} {Pfam: von Willebrand factor type A domain [PF00092.30, score=243.5]; von Willebrand factor type A domain [PF13519.8, score=104.9]} {Human: ENSG00000206384, COL6A6, collagen type VI alpha 6 chain, [Score=88.6, Expect=1e-16]; ENSG00000111799, COL12A1, collagen type XII alpha 1 chain, [Score=85.5, Expect=1e-15]} {Mouse: ENSMUSG00000032332, Col12a1, collagen, type XII, alpha 1, [Score=85.1, Expect=1e-15]; ENSMUSG00000025650, Col7a1, collagen, type VII, alpha 1, [Score=84.7, Expect=1e-15]; ENSMUSG00000022371, Col14a1, collagen, type XIV, alpha 1, [Score=83.6, Expect=3e-15]; ENSMUSG00000022324, Matn2, matrilin 2, [Score=80.9, Expect=1e-14]} {Celegans: WBGene00019570, K09E2.1, [RH, Score=60.8, Expect=1e-08]} {Smed: dd_Smed_v6_1071_0_1, dd_Smed_v6_1071_0_1, [RH, Score=142, Expect=4e-34]} {RNA1509_1372} {RNA1310_280.1} {RNA815_108}
38. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

ABCG2 0.965 - - - - 0.965 - Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
39. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

TTC16 0.964 - - - - 0.964 - Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
40. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

CNTRL 0.964 - - - - 0.964 -

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
41. MligTC455_44236 8742 182.13 Mlig455_003084, Mlig455_062811

Neo: -

Age: -

RSPH3 0.964 - - - - 0.964 -

Mlig455_003084 {REF} {Length: 2211} {Pfam: Radial spoke protein 3 [PF06098.13, score=416.8]} {Human: ENSG00000130363, RSPH3, radial spoke head 3 homolog, [RH, Score=379, Expect=7e-129]} {Mouse: ENSMUSG00000023806, Rsph3b, radial spoke 3B homolog (Chlamydomonas), [RH, Score=319, Expect=7e-104]; ENSMUSG00000073471, Rsph3a, radial spoke 3A homolog (Chlamydomonas), [RH, Score=318, Expect=5e-104]} {Dmel: FBgn0052392, CG32392, [RH, Score=187, Expect=1e-54]} {Smed: dd_Smed_v6_2287_0_1, dd_Smed_v6_2287_0_1, [RH, Score=454, Expect=9e-159]} {RNA1509_928} {RNA1310_13874} {RNA815_5098}

Mlig455_062811 {REF} {Length: 2209} {Pfam: Radial spoke protein 3 [PF06098.13, score=416.8]} {Human: ENSG00000130363, RSPH3, radial spoke head 3 homolog, [RH, Score=379, Expect=7e-129]} {Mouse: ENSMUSG00000023806, Rsph3b, radial spoke 3B homolog (Chlamydomonas), [RH, Score=319, Expect=7e-104]; ENSMUSG00000073471, Rsph3a, radial spoke 3A homolog (Chlamydomonas), [RH, Score=318, Expect=5e-104]} {Dmel: FBgn0052392, CG32392, [RH, Score=187, Expect=1e-54]} {Smed: dd_Smed_v6_2287_0_1, dd_Smed_v6_2287_0_1, [RH, Score=454, Expect=9e-159]} {RNA1509_928} {RNA1310_13874, RNA1509_928} {RNA1509_928, RNA815_5098}
42. MligTC455_50751 84 1.74 Mlig455_064759

Neo: -

Age: Up-Down-Down

GNB5 0.964 - - - - 0.964 - Mlig455_064759 {REF} {Length: 4751} {Pfam: WD domain, G-beta repeat [PF00400.34, score=127.2]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=55.7]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=34.6]; WD40-like domain [PF17005.7, score=23.8]} {Human: ENSG00000069966, GNB5, G protein subunit beta 5, [RH, Score=488, Expect=3e-174]} {Mouse: ENSMUSG00000032192, Gnb5, guanine nucleotide binding protein (G protein), beta 5, [RH, Score=489, Expect=1e-174]} {Dmel: FBgn0030011, Gbeta5, [RH, Score=502, Expect=8e-180]} {Celegans: WBGene00001680, gpb-2, Guanine nucleotide-binding protein subunit beta-2, [RH, Score=473, Expect=2e-168]} {Smed: dd_Smed_v6_10481_0_1, dd_Smed_v6_10481_0_1, [RH, Score=557, Expect=0.0]} {RNA1509_51468} {RNA1310_13844.1, RNA1509_51468} {RNA1509_51468, RNA815_14582}
43. MligTC455_37654 406 8.47 Mlig455_029446, Mlig455_029466

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.381

Region-enriched R7: 2.220/0.02232

LOXL2, LOXL4 0.963 - - - - 0.963 -

Mlig455_029446 {REF} {Length: 2317} {Pfam: Lysyl oxidase [PF01186.19, score=223.2]; Scavenger receptor cysteine-rich domain [PF00530.20, score=92.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=31.8]} {Human: ENSG00000134013, LOXL2, lysyl oxidase like 2, [Score=232, Expect=1e-68]; ENSG00000138131, LOXL4, lysyl oxidase like 4, [Score=223, Expect=4e-65]} {Mouse: ENSMUSG00000034205, Loxl2, lysyl oxidase-like 2, [Score=224, Expect=7e-66]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [Score=216, Expect=8e-63]; ENSMUSG00000000693, Loxl3, lysyl oxidase-like 3, [Score=213, Expect=9e-62]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [Score=255, Expect=8e-80]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [Score=277, Expect=6e-89]} {RNA1509_58726} {RNA1310_16786} {RNA815_6954}

Mlig455_029466 {REF} {Length: 2102} {Pfam: Lysyl oxidase [PF01186.19, score=261.1]; Scavenger receptor cysteine-rich domain [PF00530.20, score=107.2]; Scavenger receptor cysteine-rich domain [PF15494.8, score=30.3]} {Human: ENSG00000138131, LOXL4, lysyl oxidase like 4, [RH, Score=278, Expect=5e-83]; ENSG00000134013, LOXL2, lysyl oxidase like 2, [RH, Score=277, Expect=1e-82]; ENSG00000115318, LOXL3, lysyl oxidase like 3, [RH, Score=273, Expect=4e-81]} {Mouse: ENSMUSG00000000693, Loxl3, lysyl oxidase-like 3, [RH, Score=270, Expect=3e-80]; ENSMUSG00000025185, Loxl4, lysyl oxidase-like 4, [RH, Score=269, Expect=6e-80]; ENSMUSG00000034205, Loxl2, lysyl oxidase-like 2, [RH, Score=259, Expect=5e-76]} {Dmel: FBgn0034660, lox2, lysyl oxidase-like 2, [RH, Score=330, Expect=7e-106]} {Celegans: WBGene00015646, mlt-10, [Score=132, Expect=5e-32]} {Smed: dd_Smed_v6_10591_0_1, dd_Smed_v6_10591_0_1, [RH, Score=358, Expect=2e-117]} {RNA1509_58726} {RNA1310_16786} {RNA815_6954}
44. MligTC455_46649 100 2.09 Mlig455_023901

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.216/0.00086

SLC46A2 0.963 - - - - 0.963 - Mlig455_023901 {REF} {Length: 2695} {Pfam: Major Facilitator Superfamily [PF07690.18, score=79.0]} {Human: ENSG00000119457, SLC46A2, solute carrier family 46 member 2, [Score=71.6, Expect=1e-12]} {Mouse: ENSMUSG00000029650, Slc46a3, solute carrier family 46, member 3, [Score=77.4, Expect=1e-14]} {Dmel: FBgn0030576, CG15890, [RH, Score=100, Expect=5e-22]} {Celegans: WBGene00016705, C46C11.2, [RH, Score=95.9, Expect=6e-21]} {Smed: dd_Smed_v6_10822_0_1, dd_Smed_v6_10822_0_1, [Score=344, Expect=1e-113]} {RNA1509_40290} {RNA1310_13436} {RNA815_19265}
45. MligTC455_18623 381 7.95 Mlig455_008343

Neo: -

Age: -

Region-enriched R2: 1.919/0.03070

SPATS1 0.962 - - - - 0.962 - Mlig455_008343 {REF} {Length: 1483} {TRANSSPLICED} {Pfam: Spermatogenesis-associated serine-rich protein 1 [PF15160.8, score=71.5]} {Human: ENSG00000249481, SPATS1, spermatogenesis associated serine rich 1, [RH, Score=74.3, Expect=7e-15]} {Mouse: ENSMUSG00000023935, Spats1, spermatogenesis associated, serine-rich 1, [RH, Score=73.2, Expect=9e-15]} {Smed: dd_Smed_v6_8305_0_1, dd_Smed_v6_8305_0_1, [RH, Score=210, Expect=8e-68]} {RNA1509_15481} {RNA1310_26555, RNA1509_15481} {RNA1509_15481, RNA815_13979}
46. MligTC455_25395 2547 53.06 Mlig455_012103, Mlig455_029022

Neo: -

Age: -

SLC46A3 0.962 - - - - 0.962 -

Mlig455_012103 {REF} {Length: 2488} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.5]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=139, Expect=2e-35]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=5e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=2e-50]} {RNA1509_18925, RNA1509_45956} {RNA1310_14130.1, RNA1509_18925, RNA1509_45956} {RNA1509_18925, RNA1509_45956, RNA815_4522}

Mlig455_029022 {REF} {Length: 2776} {Pfam: Major Facilitator Superfamily [PF07690.18, score=64.1]} {Human: ENSG00000139508, SLC46A3, solute carrier family 46 member 3, [Score=142, Expect=2e-36]; ENSG00000076351, SLC46A1, solute carrier family 46 member 1, [Score=135, Expect=4e-34]} {Mouse: ENSMUSG00000020829, Slc46a1, solute carrier family 46, member 1, [Score=146, Expect=4e-38]} {Celegans: WBGene00021159, Y4C6B.5, [Score=50.1, Expect=3e-06]} {Smed: dd_Smed_v6_5528_0_1, dd_Smed_v6_5528_0_1, [Score=179, Expect=3e-50]} {RNA1509_18925} {RNA1310_14130.2} {RNA815_4522}
47. MligTC455_26606 1197 24.94 Mlig455_035969

Neo: -

Age: -

0.962 - - - - 0.962 - Mlig455_035969 {REF} {Length: 1942} {RNA1509_10606, RNA1509_25602} {RNA1310_13915, RNA1509_10606, RNA1509_25602} {RNA1509_10606, RNA1509_25602, RNA815_6086}
48. MligTC455_38148 787 16.4 Mlig455_067155

Neo: -

Age: -

FAT1 0.962 - - - - 0.962 - Mlig455_067155 {REF} {Length: 4823} {Pfam: Cadherin domain [PF00028.19, score=183.7]; EGF-like domain [PF00008.29, score=55.8]; Calcium-binding EGF domain [PF07645.17, score=31.4]; Laminin G domain [PF02210.26, score=24.7]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=292, Expect=3e-79]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=299, Expect=2e-81]} {Dmel: FBgn0261574, kug, kugelei, [Score=213, Expect=3e-55]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=189, Expect=9e-48]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=218, Expect=1e-56]} {RNA1509_13557} {RNA1310_1912.1} {RNA815_14235}
49. MligTC455_44971 99 2.07 Mlig455_055696

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.674

Region-enriched R4: 4.753/0.00442

ATP1B1 0.962 - - - - 0.962 - Mlig455_055696 {REF} {Length: 2498} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.1]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=125, Expect=7e-33]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=127, Expect=8e-34]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=164, Expect=8e-48]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=4e-43]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [RH, Score=244, Expect=2e-79]} {RNA1509_10526} {RNA1310_27937} {RNA815_16874}
50. MligTC455_46255 2218 46.21 Mlig455_024833

Neo: -

Age: logFC(26M/2M)=-0.329

CASC1 0.962 - - - - 0.962 - Mlig455_024833 {REF} {Length: 2822} {Pfam: Cancer susceptibility candidate 1 N-terminus [PF15927.7, score=170.2]; Cancer susceptibility candidate 1 C-terminal [PF12366.10, score=30.7]} {Human: ENSG00000118307, CASC1, cancer susceptibility 1, [RH, Score=319, Expect=1e-97]} {Mouse: ENSMUSG00000043541, Casc1, cancer susceptibility candidate 1, [RH, Score=293, Expect=5e-88]} {Dmel: FBgn0030889, CG15373, [RH, Score=82.4, Expect=8e-16]} {Smed: dd_Smed_v6_11291_0_1, dd_Smed_v6_11291_0_1, [RH, Score=521, Expect=7e-175]} {RNA1509_1842} {RNA1310_6962.1} {RNA815_2139}
51. MligTC455_50684 144 3.01 Mlig455_008825

Neo: -

Age: Up-Down-Down

0.962 - - - - 0.962 - Mlig455_008825 {REF} {Length: 1594} {RNA1509_24338} {RNA1310_77.2} {RNA815_489}
52. MligTC455_13383 94 1.96 Mlig455_026678

Neo: -

Age: -

0.961 - - - - 0.961 - Mlig455_026678 {REF} {Length: 555} {NoTransDecoderORF} {RNA1509_23329} {RNA1310_2013} {RNA815_565}
53. MligTC455_24519 1035 21.55 Mlig455_026505

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.364/0.03756

DNAH10 0.961 - - - - 0.961 - Mlig455_026505 {REF} {Length: 14733} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=521.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=390.5]; P-loop containing dynein motor region D4 [PF12780.9, score=341.0]; Dynein heavy chain C-terminal domain [PF18199.3, score=306.8]; ATP-binding dynein motor region [PF12781.9, score=282.5]; P-loop containing dynein motor region [PF12775.9, score=264.2]; Microtubule-binding stalk of dynein motor [PF12777.9, score=214.4]; Dynein heavy chain AAA lid domain [PF18198.3, score=174.9]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=142.3]; AAA domain (dynein-related subfamily) [PF07728.16, score=92.9]; Dynein heavy chain AAA lid domain [PF17852.3, score=81.8]; AAA+ lid domain [PF17857.3, score=63.2]; AAA domain [PF13401.8, score=44.6]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=34.7]; AAA ATPase domain [PF13191.8, score=31.6]; AAA domain [PF13238.8, score=24.7]; MoxR domain in the MoxR-vWA-beta-propeller ternary systems [PF20030.1, score=21.4]; Sigma-54 interaction domain [PF00158.28, score=21.3]} {Human: ENSG00000281935, DNAH10, dynein axonemal heavy chain 10, [RH, Score=4662, Expect=0.0]} {Mouse: ENSMUSG00000038011, Dnah10, dynein, axonemal, heavy chain 10, [Score=4676, Expect=0.0]} {Dmel: FBgn0013813, Dhc98D, Dynein heavy chain at 89D, [RH, Score=3860, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=1408, Expect=0.0]} {Smed: dd_Smed_v6_5169_0_1, dd_Smed_v6_5169_0_1, [RH, Score=4698, Expect=0.0]} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1310_40.1, RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395} {RNA1509_19877, RNA1509_2715, RNA1509_29080, RNA1509_395, RNA815_20}
54. MligTC455_28074 91 1.89 Mlig455_042655, Mlig455_047014

Neo: -

Age: -

0.96 - - - - 0.960 -

Mlig455_042655 {REF} {Length: 956} {NoTransDecoderORF} {RNA1509_27021} {RNA1310_14467} {RNA815_5428.1}

Mlig455_047014 {REF} {Length: 5125} {RNA1509_31395} {RNA1310_10847.1} {RNA815_5428.1}
55. MligTC455_36003 363 7.55 Mlig455_026590

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.251

DNAH6 0.96 - - - - 0.960 - Mlig455_026590 {REF} {Length: 15062} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=480.2]; P-loop containing dynein motor region D4 [PF12780.9, score=291.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=254.7]; ATP-binding dynein motor region [PF12781.9, score=232.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=229.2]; P-loop containing dynein motor region [PF12775.9, score=203.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=125.5]; Dynein heavy chain AAA lid domain [PF18198.3, score=122.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=112.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=85.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=50.9]; AAA domain [PF13401.8, score=49.6]; AAA ATPase domain [PF13191.8, score=46.7]; AAA+ lid domain [PF17857.3, score=46.7]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=45.9]; AAA domain [PF13238.8, score=23.0]; AAA domain [PF13671.8, score=20.8]; NACHT domain [PF05729.14, score=20.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.7]} {Human: ENSG00000115423, DNAH6, dynein axonemal heavy chain 6, [Score=1591, Expect=0.0]; ENSG00000185842, DNAH14, dynein axonemal heavy chain 14, [Score=1554, Expect=0.0]} {Mouse: ENSMUSG00000052861, Dnah6, dynein, axonemal, heavy chain 6, [Score=1545, Expect=0.0]} {Dmel: FBgn0283476, Dhc16F, Dynein heavy chain at 16F, [Score=1207, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=628, Expect=5e-180]} {Smed: dd_Smed_v6_10969_0_1, dd_Smed_v6_10969_0_1, [RH, Score=2792, Expect=0.0]} {RNA1509_3937, RNA1509_49112} {RNA1310_38.1, RNA1509_49112} {RNA1509_49112, RNA815_142}
56. MligTC455_31872 115 2.4 Mlig455_031280

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_031280 {REF} {Length: 4437} {RNA1509_44223} {RNA1310_53789} {RNA815_61017}
57. MligTC455_43767 1310 27.29 Mlig455_048807

Neo: -

Age: Down-Down-Up

EFHB 0.959 - - - - 0.959 - Mlig455_048807 {REF} {Length: 2201} {TRANSSPLICED} {Pfam: EF-hand domain pair [PF13499.8, score=45.4]; EF hand [PF00036.34, score=42.2]; EF-hand domain [PF13405.8, score=40.2]; Family of unknown function (DUF5580) [PF17743.3, score=32.2]; EF hand [PF13202.8, score=31.1]; EF-hand domain pair [PF13833.8, score=18.8]} {Human: ENSG00000163576, EFHB, EF-hand domain family member B, [RH, Score=386, Expect=1e-125]} {Mouse: ENSMUSG00000023931, Efhb, EF hand domain family, member B, [RH, Score=359, Expect=7e-114]} {Dmel: FBgn0004910, Eip63F-1, Ecdysone-induced protein 63F 1, [Score=53.1, Expect=6e-08]} {Celegans: WBGene00000286, cal-2, CALmodulin related genes; Calmodulin-like protein, [Score=52.8, Expect=7e-08]} {Smed: dd_Smed_v6_11909_0_1, dd_Smed_v6_11909_0_1, [RH, Score=351, Expect=3e-114]} {RNA1509_2205} {RNA1310_7693} {RNA815_3913}
58. MligTC455_52083 972 20.26 Mlig455_009237, Mlig455_009643

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.031/0.00909

FAT3 0.959 - - - - 0.959 -

Mlig455_009237 {REF} {Length: 9383} {Pfam: Cadherin domain [PF00028.19, score=291.4]; Laminin G domain [PF02210.26, score=96.4]; Cadherin cytoplasmic region [PF01049.19, score=79.9]; Laminin G domain [PF00054.25, score=77.7]; Cadherin-like [PF16184.7, score=57.2]; Cadherin-like [PF08266.14, score=20.1]} {Human: ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]; ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=280, Expect=1e-74]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=279, Expect=3e-74]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=716, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=478, Expect=2e-135]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=175, Expect=4e-43]} {RNA1509_5439} {RNA1310_149} {RNA815_168}

Mlig455_009643 {REF} {Length: 9400} {Pfam: Cadherin domain [PF00028.19, score=300.2]; Laminin G domain [PF02210.26, score=97.0]; Cadherin cytoplasmic region [PF01049.19, score=80.9]; Laminin G domain [PF00054.25, score=78.3]; Cadherin-like [PF16184.7, score=54.5]; Cadherin-like [PF08266.14, score=22.1]} {Human: ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]; ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=275, Expect=3e-73]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=720, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=468, Expect=2e-132]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=169, Expect=1e-41]} {RNA1509_5439} {RNA1310_149, RNA1509_5439} {RNA1509_5439, RNA815_168}
59. MligTC455_14494 310 6.46 Mlig455_019231

Neo: -

Age: -

ANKEF1 0.958 - - - - 0.958 - Mlig455_019231 {REF} {Length: 2621} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=159.3]; Ankyrin repeats (many copies) [PF13637.8, score=133.0]; Ankyrin repeat [PF13606.8, score=111.4]; Ankyrin repeats (many copies) [PF13857.8, score=106.3]; Ankyrin repeat [PF00023.32, score=97.4]} {Human: ENSG00000132623, ANKEF1, ankyrin repeat and EF-hand domain containing 1, [Score=437, Expect=9e-143]} {Mouse: ENSMUSG00000074771, Ankef1, ankyrin repeat and EF-hand domain containing 1, [Score=434, Expect=1e-141]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=95.9, Expect=5e-20]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=80.9, Expect=2e-15]} {Smed: dd_Smed_v6_12476_0_1, dd_Smed_v6_12476_0_1, [Score=577, Expect=0.0]} {RNA1509_22782} {RNA1310_8283, RNA1509_22782} {RNA1509_22782, RNA815_2494.1}
60. MligTC455_15913 197 4.11 Mlig455_055582

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.633

0.958 - - - - 0.958 - Mlig455_055582 {REF} {Length: 2651} {Pfam: Universal stress protein family [PF00582.28, score=78.3]} {Smed: dd_Smed_v6_7254_0_1, dd_Smed_v6_7254_0_1, [RH, Score=107, Expect=4e-29]} {RNA1509_30118, RNA1509_39041} {RNA1310_41795.1, RNA1509_39041} {RNA1509_39041, RNA815_18378}
61. MligTC455_17998 727 15.15 Mlig455_008453, Mlig455_031366, Mlig455_056517

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.576

ANK1, ANK2 0.958 - - - - 0.958 -

Mlig455_008453 {REF} {Length: 2485} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=83.8]; Ankyrin repeat [PF00023.32, score=78.9]; Caspase domain [PF00656.24, score=74.8]; Ankyrin repeat [PF13606.8, score=66.2]; Ankyrin repeats (many copies) [PF13637.8, score=66.1]; Ankyrin repeats (many copies) [PF13857.8, score=61.1]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=83.6, Expect=3e-16]; ENSG00000145362, ANK2, ankyrin 2, [Score=79.7, Expect=6e-15]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=89.4, Expect=3e-18]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=84.0, Expect=1e-16]} {Celegans: WBGene00012124, T28D6.4, [Score=75.5, Expect=3e-14]} {Smed: dd_Smed_v6_2072_0_20, dd_Smed_v6_2072_0_20, [Score=77.0, Expect=1e-14]} {RNA1509_6998} {RNA1310_4219} {RNA815_1303}

Mlig455_031366 {REF} {Length: 3367} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=181.0]; Ankyrin repeats (many copies) [PF13637.8, score=143.2]; Ankyrin repeat [PF00023.32, score=133.3]; Ankyrin repeat [PF13606.8, score=125.8]; Ankyrin repeats (many copies) [PF13857.8, score=114.8]; Caspase domain [PF00656.24, score=73.5]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=115, Expect=1e-25]; ENSG00000029534, ANK1, ankyrin 1, [Score=112, Expect=1e-24]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=129, Expect=5e-30]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=108, Expect=8e-24]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=114, Expect=1e-25]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=108, Expect=5e-24]} {RNA1509_6998} {RNA1310_4219} {RNA815_1303}

Mlig455_056517 {REF} {Length: 3171} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=156.2]; Ankyrin repeat [PF00023.32, score=125.3]; Ankyrin repeats (many copies) [PF13637.8, score=123.3]; Ankyrin repeat [PF13606.8, score=115.2]; Ankyrin repeats (many copies) [PF13857.8, score=101.8]; Caspase domain [PF00656.24, score=70.7]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=97.1, Expect=5e-20]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=97.4, Expect=3e-20]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=98.6, Expect=9e-21]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=95.9, Expect=6e-20]} {Smed: dd_Smed_v6_10835_0_2, dd_Smed_v6_10835_0_2, [Score=92.4, Expect=5e-19]} {RNA1509_57394, RNA1509_6998} {RNA1310_4219, RNA1509_57394} {RNA1509_57394, RNA815_1303}
62. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

WDR49 0.958 - - - - 0.958 - Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
63. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

GRIA2 0.958 - - - - 0.958 -

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
64. MligTC455_38205 600 12.5 Mlig455_057698

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.274

0.958 - - - - 0.958 - Mlig455_057698 {REF} {Length: 1671} {Pfam: Protein of unknown function with motif GDWWSH [PF15667.7, score=76.0]} {Smed: dd_Smed_v6_6622_0_1, dd_Smed_v6_6622_0_1, [RH, Score=116, Expect=1e-30]} {RNA1509_16386} {RNA1310_17948.1} {RNA815_6839.1}
65. MligTC455_42171 910 18.96 Mlig455_050223

Neo: -

Age: -

Region-enriched R2: 1.714/0.04973

0.958 - - - - 0.958 - Mlig455_050223 {REF} {Length: 2134} {Pfam: Innexin [PF00876.20, score=296.2]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=95.5, Expect=5e-21]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=208, Expect=6e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=276, Expect=2e-87]} {RNA1509_10527} {RNA1310_14408} {RNA815_844.2}
66. MligTC455_43972 1061 22.11 Mlig455_047704

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_047704 {REF} {Length: 2155} {TRANSSPLICED} {RNA1509_7618} {RNA1310_9007} {RNA815_27926.1}
67. MligTC455_49044 181 3.77 Mlig455_055888

Neo: -

Age: -

Region-enriched R4: 5.423/0.00960

0.958 - - - - 0.958 - Mlig455_055888 {REF} {Length: 508} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_15967} {RNA1310_39655} {RNA815_17269}
68. MligTC455_17333 251 5.22 Mlig455_018094

Neo: -

Age: logFC(26M/2M)=-0.324

CFAP77 0.957 - - - - 0.957 - Mlig455_018094 {REF} {Length: 1669} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4483) [PF14825.8, score=38.0]} {Human: ENSG00000188523, CFAP77, cilia and flagella associated protein 77, [Score=62.4, Expect=1e-10]} {Smed: dd_Smed_v6_5179_0_1, dd_Smed_v6_5179_0_1, [Score=64.3, Expect=5e-12]} {RNA1509_11420} {RNA1310_11821} {RNA815_16183}
69. MligTC455_18603 3778 78.7 Mlig455_050242

Neo: -

Age: -

CCDC39 0.957 - - - - 0.957 - Mlig455_050242 {REF} {Length: 3281} {Human: ENSG00000284862, CCDC39, coiled-coil domain containing 39, [RH, Score=698, Expect=0.0]} {Mouse: ENSMUSG00000027676, Ccdc39, coiled-coil domain containing 39, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0037276, CG17387, [RH, Score=157, Expect=4e-39]} {Smed: dd_Smed_v6_5955_0_1, dd_Smed_v6_5955_0_1, [RH, Score=779, Expect=0.0]} {RNA1509_738} {RNA1310_4021} {RNA815_1219}
70. MligTC455_19773 282 5.88 Mlig455_040702, Mlig455_064571

Neo: -

Age: logFC(26M/2M)=-0.398

0.957 - - - - 0.957 -

Mlig455_040702 {REF} {Length: 1993} {RNA1509_27263} {RNA1310_20057.1, RNA1509_27263} {RNA1509_27263, RNA815_31718}

Mlig455_064571 {REF} {Length: 2145} {RNA1509_27263} {RNA1310_20057.1} {RNA815_31718}
71. MligTC455_24553 855 17.8 Mlig455_023662

Neo: -

Age: logFC(26M/2M)=-1.366

IQCE 0.957 - - - - 0.957 - Mlig455_023662 {REF} {Length: 4080} {TRANSSPLICED} {Human: ENSG00000106012, IQCE, IQ motif containing E, [Score=102, Expect=4e-23]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [Score=102, Expect=5e-23]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [Score=65.1, Expect=1e-11]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}
72. MligTC455_43906 878 18.29 Mlig455_044333, Mlig455_044345

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.277

RAI14 0.957 - - - - 0.957 -

Mlig455_044333 {REF} {Length: 5825} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=81.1]; Ankyrin repeat [PF00023.32, score=72.8]; Ankyrin repeats (many copies) [PF13637.8, score=63.6]; Ankyrin repeat [PF13606.8, score=48.5]; Ankyrin repeats (many copies) [PF13857.8, score=44.2]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=90.1, Expect=3e-17]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=94.4, Expect=9e-19]; ENSMUSG00000007827, Ankrd26, ankyrin repeat domain 26, [Score=89.7, Expect=3e-17]} {Dmel: FBgn0039590, CG10011, [Score=82.4, Expect=4e-15]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=85.9, Expect=3e-16]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=73.9, Expect=7e-13]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}

Mlig455_044345 {REF} {Length: 6035} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=87.7]; Ankyrin repeat [PF00023.32, score=72.9]; Ankyrin repeats (many copies) [PF13637.8, score=66.8]; Ankyrin repeats (many copies) [PF13857.8, score=50.5]; Ankyrin repeat [PF13606.8, score=50.0]} {Human: ENSG00000039560, RAI14, retinoic acid induced 14, [Score=94.7, Expect=9e-19]; ENSG00000065413, ANKRD44, ankyrin repeat domain 44, [Score=92.0, Expect=6e-19]} {Mouse: ENSMUSG00000022246, Rai14, retinoic acid induced 14, [Score=99.4, Expect=3e-20]} {Dmel: FBgn0039590, CG10011, [Score=87.4, Expect=1e-16]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=86.3, Expect=2e-16]} {Smed: dd_Smed_v6_7952_0_2, dd_Smed_v6_7952_0_2, [Score=80.5, Expect=8e-15]} {RNA1509_7603} {RNA1310_960.3} {RNA815_5173}
73. MligTC455_52356 37 0.76 Mlig455_042513

Neo: -

Age: -

0.957 - - - - 0.957 - Mlig455_042513 {REF} {Length: 755} {NoTransDecoderORF}
74. MligTC455_18964 466 9.7 Mlig455_010572

Neo: -

Age: Down-Up-Up

STK38L 0.956 - - - - 0.956 - Mlig455_010572 {REF} {Length: 1993} {Pfam: Protein kinase domain [PF00069.27, score=146.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=75.4]; ABC1 atypical kinase-like domain [PF03109.18, score=32.4]; Phosphotransferase enzyme family [PF01636.25, score=19.9]} {Human: ENSG00000211455, STK38L, serine/threonine kinase 38 like, [Score=400, Expect=3e-139]; ENSG00000112079, STK38, serine/threonine kinase 38, [Score=400, Expect=8e-139]} {Mouse: ENSMUSG00000024006, Stk38, serine/threonine kinase 38, [Score=402, Expect=2e-142]; ENSMUSG00000001630, Stk38l, serine/threonine kinase 38 like, [Score=402, Expect=8e-140]} {Dmel: FBgn0003744, trc, tricornered, [Score=397, Expect=2e-138]} {Celegans: WBGene00004727, sax-1, Serine/threonine-protein kinase sax-1, [Score=367, Expect=3e-126]} {Smed: dd_Smed_v6_6462_0_2, dd_Smed_v6_6462_0_2, [Score=412, Expect=2e-142]} {RNA1509_22842} {RNA1310_31611, RNA1509_22842} {RNA1509_22842, RNA815_4455}
75. MligTC455_34048 264 5.5 Mlig455_065825

Neo: -

Age: -

0.956 - - - - 0.956 - Mlig455_065825 {REF} {Length: 1976} {NoTransDecoderORF} {RNA1509_34217, RNA1509_38071} {RNA1310_27951, RNA1509_34217} {RNA1509_34217, RNA815_16586}
76. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

VASH2 0.956 - - - - 0.956 - Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
77. MligTC455_44432 1115 23.23 Mlig455_015671, Mlig455_062480

Neo: -

Age: logFC(26M/2M)=0.247

F5 0.956 - - - - 0.956 -

Mlig455_015671 {REF} {Length: 5764} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.3, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.8, Expect=6e-09]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=69.3, Expect=4e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=50.8, Expect=6e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=87.8, Expect=3e-17]} {RNA1509_2035} {RNA1310_951.1, RNA1509_2035} {RNA1509_2035, RNA815_305}

Mlig455_062480 {REF} {Length: 6260} {Pfam: F5/8 type C domain [PF00754.27, score=47.5]} {Human: ENSG00000198734, F5, coagulation factor V, [Score=64.7, Expect=2e-09]; ENSG00000185010, F8, coagulation factor VIII, [Score=62.0, Expect=1e-08]} {Mouse: ENSMUSG00000031196, F8, coagulation factor VIII, [Score=68.2, Expect=9e-11]} {Dmel: FBgn0053531, Ddr, Discoidin domain receptor, [Score=53.5, Expect=1e-06]} {Smed: dd_Smed_v6_15631_0_1, dd_Smed_v6_15631_0_1, [Score=89.7, Expect=8e-18]} {RNA1509_2035, RNA1509_37215} {RNA1310_951.1, RNA1509_37215} {RNA1509_37215, RNA815_305}
78. MligTC455_53960 381 7.93 Mlig455_039523

Neo: -

Age: logFC(26M/2M)=-0.527

Region-enriched R2: 1.863/0.02753

TTLL7 0.956 - - - - 0.956 - Mlig455_039523 {REF} {Length: 2811} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=44.5]} {Human: ENSG00000137941, TTLL7, tubulin tyrosine ligase like 7, [Score=146, Expect=5e-37]} {Mouse: ENSMUSG00000036745, Ttll7, tubulin tyrosine ligase-like family, member 7, [Score=261, Expect=2e-76]} {Dmel: FBgn0039501, CG5987, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_13600_0_1, dd_Smed_v6_13600_0_1, [Score=118, Expect=1e-27]} {RNA1509_8901} {RNA1310_4651} {RNA815_1757}
79. MligTC455_15330 373 7.77 Mlig455_020220

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.289

0.955 - - - - 0.955 - Mlig455_020220 {REF} {Length: 2115} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=41.4]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=82.0, Expect=3e-20]} {RNA1509_28885, RNA1509_54654} {RNA1310_42962.2, RNA1509_28885, RNA1509_54654} {RNA1509_28885, RNA1509_54654, RNA815_23071}
80. MligTC455_30192 1664 34.66 Mlig455_026693

Neo: -

Age: -

FOXRED2 0.955 - - - - 0.955 - Mlig455_026693 {REF} {Length: 18036} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=147.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=45.8]; HI0933-like protein [PF03486.16, score=31.1]; FAD dependent oxidoreductase [PF01266.26, score=26.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=25.0]; FAD binding domain [PF01494.21, score=22.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=22.5]; Flavin containing amine oxidoreductase [PF01593.26, score=21.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=20.1]} {Human: ENSG00000100350, FOXRED2, FAD dependent oxidoreductase domain containing 2, [RH, Score=493, Expect=4e-167]} {Mouse: ENSMUSG00000016552, Foxred2, FAD-dependent oxidoreductase domain containing 2, [RH, Score=498, Expect=3e-169]} {Celegans: WBGene00001479, fmo-4, Flavin-containing monooxygenase, [Score=53.5, Expect=4e-07]} {Smed: dd_Smed_v6_12138_0_1, dd_Smed_v6_12138_0_1, [RH, Score=474, Expect=4e-161]} {RNA1509_13675, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1310_861.1, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978, RNA815_570.1}
81. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

XRRA1 0.955 - - - - 0.955 - Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
82. MligTC455_34564 216 4.51 Mlig455_045027

Neo: -

Age: -

VASH1 0.955 - - - - 0.955 - Mlig455_045027 {REF} {Length: 1457} {Pfam: Vasohibin [PF14822.8, score=320.1]} {Human: ENSG00000071246, VASH1, vasohibin 1, [RH, Score=258, Expect=2e-83]; ENSG00000143494, VASH2, vasohibin 2, [RH, Score=256, Expect=7e-83]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=261, Expect=7e-85]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=254, Expect=2e-82]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=233, Expect=4e-75]} {RNA1509_59274} {RNA1310_23626.1} {RNA815_21188.1}
83. MligTC455_29373 3437 71.6 Mlig455_034659

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_034659 {REF} {Length: 1882} {RNA1509_3330} {RNA1310_13623.1} {RNA815_4944.1}
84. MligTC455_30618 652 13.59 Mlig455_031172

Neo: -

Age: logFC(26M/2M)=-0.520

ITPR2 0.954 - - - - 0.954 - Mlig455_031172 {REF} {Length: 9583} {Pfam: RIH domain [PF01365.23, score=93.8]; Inositol 1,4,5-trisphosphate/ryanodine receptor [PF08709.13, score=76.1]; MIR domain [PF02815.21, score=44.8]} {Human: ENSG00000123104, ITPR2, inositol 1,4,5-trisphosphate receptor type 2, [Score=214, Expect=5e-55]; ENSG00000150995, ITPR1, inositol 1,4,5-trisphosphate receptor type 1, [Score=205, Expect=3e-52]} {Mouse: ENSMUSG00000042644, Itpr3, inositol 1,4,5-triphosphate receptor 3, [Score=222, Expect=2e-57]; ENSMUSG00000030287, Itpr2, inositol 1,4,5-triphosphate receptor 2, [Score=213, Expect=8e-55]} {Dmel: FBgn0010051, Itp-r83A, Inositol 1,4,5,-tris-phosphate receptor, [Score=194, Expect=3e-49]} {Celegans: WBGene00002173, itr-1, Inositol 1,4,5-trisphosphate receptor itr-1, [Score=140, Expect=7e-33]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=1298, Expect=0.0]} {RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1310_129.1, RNA1509_23724, RNA1509_55174, RNA1509_5518} {RNA1509_23724, RNA1509_55174, RNA1509_5518, RNA815_62.1}
85. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

MAPK15 0.954 - - - - 0.954 -

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
86. MligTC455_16955 1687 35.15 Mlig455_051000

Neo: -

Age: Down-Up-Up

PLA2G7 0.953 - - - - 0.953 - Mlig455_051000 {REF} {Length: 1559} {TRANSSPLICED} {Pfam: Platelet-activating factor acetylhydrolase, isoform II [PF03403.15, score=213.8]; alpha/beta hydrolase fold [PF00561.22, score=28.3]; Alpha/beta hydrolase family [PF12697.9, score=26.6]; Serine aminopeptidase, S33 [PF12146.10, score=25.3]; Chlorophyllase enzyme [PF12740.9, score=20.4]} {Human: ENSG00000146070, PLA2G7, phospholipase A2 group VII, [RH, Score=171, Expect=1e-48]} {Mouse: ENSMUSG00000037366, Pafah2, platelet-activating factor acetylhydrolase 2, [RH, Score=163, Expect=5e-46]; ENSMUSG00000023913, Pla2g7, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), [RH, Score=158, Expect=1e-43]} {Celegans: WBGene00003906, paf-1, PAF-1; PAF-acetylhydrolase, [RH, Score=142, Expect=2e-38]} {RNA1509_16678, RNA1509_21980} {RNA1310_21439.1, RNA1509_16678, RNA1509_21980} {RNA1509_16678, RNA1509_21980, RNA815_19873}
87. MligTC455_21470 491 10.23 Mlig455_028994

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

KCNMA1 0.953 - - - - 0.953 - Mlig455_028994 {REF} {Length: 4059} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=82.1]; Ion channel [PF07885.18, score=48.7]; Ion transport protein [PF00520.33, score=31.6]; TrkA-N domain [PF02254.20, score=27.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=484, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=482, Expect=5e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=479, Expect=1e-150]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=461, Expect=5e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=490, Expect=3e-155]} {RNA1509_10617} {RNA1310_2480.1} {RNA815_984.1}
88. MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

0.953 - - - - 0.953 -

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}
89. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 0.953 - - - - 0.953 - Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
90. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

0.953 - - - - 0.953 - Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
91. MligTC455_47868 5452 113.57 Mlig455_031216

Neo: -

Age: logFC(26M/2M)=-0.277

TEKT1 0.953 - - - - 0.953 - Mlig455_031216 {REF} {Length: 1751} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=439.2]} {Human: ENSG00000167858, TEKT1, tektin 1, [RH, Score=379, Expect=4e-129]} {Mouse: ENSMUSG00000020799, Tekt1, tektin 1, [RH, Score=373, Expect=9e-127]} {Dmel: FBgn0052820, CG32820, [Score=217, Expect=4e-65]} {Smed: dd_Smed_v6_3287_0_2, dd_Smed_v6_3287_0_2, [RH, Score=448, Expect=1e-156]} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1310_15062.1, RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215, RNA815_6688}
92. MligTC455_49004 1711 35.64 Mlig455_040452, Mlig455_042848, Mlig455_043610

Neo: -

Age: logFC(26M/2M)=-0.274

Region-enriched R2: 1.355/0.00285

CCDC180 0.953 - - - - 0.953 -

Mlig455_040452 {REF} {Length: 5565} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=418.0]; Domain of unknown function (DUF4456) [PF14644.8, score=172.8]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=410, Expect=3e-117]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=275, Expect=3e-74]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=399, Expect=4e-116]} {RNA1509_8832} {RNA1310_898.2} {RNA815_672.1}

Mlig455_042848 {REF} {Length: 5466} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=419.7]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [Score=274, Expect=1e-74]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=275, Expect=4e-75]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [Score=254, Expect=7e-69]} {RNA1509_8832} {RNA1310_898.1} {RNA815_672.1}

Mlig455_043610 {REF} {Length: 5567} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4455) [PF14643.8, score=413.1]; Domain of unknown function (DUF4456) [PF14644.8, score=171.2]} {Human: ENSG00000197816, CCDC180, coiled-coil domain containing 180, [RH, Score=405, Expect=1e-115]} {Mouse: ENSMUSG00000035539, Ccdc180, coiled-coil domain containing 180, [RH, Score=270, Expect=7e-73]} {Smed: dd_Smed_v6_12302_0_1, dd_Smed_v6_12302_0_1, [RH, Score=398, Expect=1e-115]} {RNA1509_8832} {RNA1310_898.2} {RNA815_672.1}
93. MligTC455_19470 80 1.66 Mlig455_002707

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_002707 {REF} {Length: 260} {NoTransDecoderORF} {RNA1509_46200} {RNA1310_613.1} {RNA815_5431}
94. MligTC455_47531 766 15.96 Mlig455_010404

Neo: -

Age: Down-Down-Up

Region-enriched R2: 2.453/0.00086
Region-enriched R3: 1.745/0.03880

0.952 - - - - 0.952 - Mlig455_010404 {REF} {Length: 2728} {RNA1509_28525} {RNA1310_16828, RNA1509_28525} {RNA1509_28525, RNA815_10712}
95. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

FLNB 0.951 - - - - 0.951 -

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
96. MligTC455_39608 6604 137.59 Mlig455_023921, Mlig455_046482

Neo: -

Age: -

APP 0.951 - - - - 0.951 -

Mlig455_023921 {REF} {Length: 3702} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.7]; E2 domain of amyloid precursor protein [PF12925.9, score=43.8]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.1]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.3, Expect=3e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.0, Expect=3e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.9, Expect=6e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=134, Expect=7e-33]} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1310_3149.1, RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900, RNA815_958.1}

Mlig455_046482 {REF} {Length: 3710} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=47.8]; E2 domain of amyloid precursor protein [PF12925.9, score=43.1]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.2]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.7, Expect=2e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.5, Expect=9e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=9e-23]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=138, Expect=3e-34]} {RNA1509_11651, RNA1509_35488} {RNA1310_3149.1, RNA1509_35488} {RNA1509_35488, RNA815_958.1}
97. MligTC455_17309 119 2.48 Mlig455_045358

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.461

0.95 - - - - 0.950 - Mlig455_045358 {REF} {Length: 2422} {Smed: dd_Smed_v6_17523_0_1, dd_Smed_v6_17523_0_1, [Score=62.8, Expect=3e-12]} {RNA1310_22111} {RNA815_10307}
98. MligTC455_21558 31 0.64 Mlig455_048987

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_048987 {REF} {Length: 5660} {Pfam: Helix-turn-helix domain [PF13936.8, score=20.7]; Helix-turn-helix domain [PF18024.3, score=20.4]; Homeodomain-like domain [PF13384.8, score=19.4]} {RNA1509_2515} {RNA1310_11002} {RNA815_3258.1}
99. MligTC455_24735 1026 21.38 Mlig455_003136

Neo: -

Age: logFC(26M/2M)=-0.296

VWA3B 0.95 - - - - 0.950 - Mlig455_003136 {REF} {Length: 2787} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=231.3]; DNA repair protein Crb2 Tudor domain [PF18115.3, score=42.4]; SGF29 tudor-like domain [PF07039.13, score=39.7]; Jumonji domain-containing protein 2A Tudor domain [PF18104.3, score=33.4]; SPX domain [PF03105.21, score=20.6]} {Human: ENSG00000168658, VWA3B, von Willebrand factor A domain containing 3B, [RH, Score=79.7, Expect=4e-15]} {RNA1509_5206} {RNA1310_5951.1, RNA1509_5206} {RNA1509_5206, RNA815_1760.1}
100. MligTC455_29452 881 18.34 Mlig455_044747

Neo: -

Age: -

LMNTD1 0.95 - - - - 0.950 - Mlig455_044747 {REF} {Length: 9990} {tRNA: Phe(GAA), score=86.5} {Pfam: Intermediate filament protein [PF00038.23, score=53.6]; Lamin Tail Domain [PF00932.21, score=40.3]; Mechanosensitive ion channel porin domain [PF12795.9, score=20.9]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=146, Expect=3e-37]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=3e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.8, Expect=8e-10]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [Score=208, Expect=5e-56]} {RNA1509_20212} {RNA1310_1500.1} {RNA815_1147.1}

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