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Results for MligTC455_43588

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_43588 1419 29.57 Mlig455_002159, Mlig455_002304

Neo: -

Age: logFC(26M/2M)=0.283

Region-enriched R4: 2.039/0.00360

CYP2J2

Mlig455_002159 {REF} {Length: 1922} {TRANSSPLICED} {Pfam: Cytochrome P450 [PF00067.24, score=324.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=194, Expect=3e-55]; ENSG00000138061, CYP1B1, cytochrome P450 family 1 subfamily B member 1, [Score=188, Expect=8e-53]} {Mouse: ENSMUSG00000003555, Cyp17a1, cytochrome P450, family 17, subfamily a, polypeptide 1, [RH, Score=197, Expect=2e-56]} {Dmel: FBgn0004959, phm, Peptidylglycine-alpha-hydroxylating monooxygenase, [Score=143, Expect=2e-36]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=160, Expect=3e-43]} {Smed: dd_Smed_v6_3919_0_1, dd_Smed_v6_3919_0_1, [Score=156, Expect=8e-42]} {RNA1509_5363} {RNA1310_11839} {RNA815_5371}

Mlig455_002304 {REF} {Length: 2481} {TRANSSPLICED} {Pfam: Cytochrome P450 [PF00067.24, score=324.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=194, Expect=3e-55]; ENSG00000138061, CYP1B1, cytochrome P450 family 1 subfamily B member 1, [Score=188, Expect=8e-53]} {Mouse: ENSMUSG00000003555, Cyp17a1, cytochrome P450, family 17, subfamily a, polypeptide 1, [RH, Score=197, Expect=2e-56]} {Dmel: FBgn0004959, phm, Peptidylglycine-alpha-hydroxylating monooxygenase, [Score=143, Expect=2e-36]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=160, Expect=3e-43]} {Smed: dd_Smed_v6_3919_0_1, dd_Smed_v6_3919_0_1, [Score=156, Expect=8e-42]} {RNA1509_5363} {RNA1310_11839, RNA1509_5363} {RNA1509_5363, RNA815_5371}

Cumulative graph for MligTC455_43588

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -7.851 5.193 0.00508 0.22406
RegionR2 1.522 5.193 0.01305 0.11905
RegionR3 1.106 5.193 0.08555 0.51735
RegionR4 2.039 5.193 0.00026 0.00360
RegionR5 1.404 5.193 0.01092 0.06153
RegionR6 1.434 5.193 0.01264 0.19449
RegionR7 0.518 5.193 0.55775 1.00000
RegionR8 -0.171 5.193 0.90007 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.986 5.193 0.99989 1.00000
RegenerationR2 -0.405 5.193 0.16275 0.59988
RegenerationR3 0.007 5.193 0.98369 1.00000
RegenerationR4 -0.366 5.193 0.28099 0.72608
RegenerationR5 -0.388 5.193 0.21459 0.64955
RegenerationR6 -0.382 5.193 0.25405 0.60395
RegenerationBL 0.193 5.193 0.64571 0.98343
RegenerationTP 1.077 5.193 0.02587 0.27118


Genes with expression patterns similar to MligTC455_43588

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_43588 1419 29.57 Mlig455_002159, Mlig455_002304

Neo: -

Age: logFC(26M/2M)=0.283

Region-enriched R4: 2.039/0.00360

CYP2J2 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_002159 {REF} {Length: 1922} {TRANSSPLICED} {Pfam: Cytochrome P450 [PF00067.24, score=324.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=194, Expect=3e-55]; ENSG00000138061, CYP1B1, cytochrome P450 family 1 subfamily B member 1, [Score=188, Expect=8e-53]} {Mouse: ENSMUSG00000003555, Cyp17a1, cytochrome P450, family 17, subfamily a, polypeptide 1, [RH, Score=197, Expect=2e-56]} {Dmel: FBgn0004959, phm, Peptidylglycine-alpha-hydroxylating monooxygenase, [Score=143, Expect=2e-36]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=160, Expect=3e-43]} {Smed: dd_Smed_v6_3919_0_1, dd_Smed_v6_3919_0_1, [Score=156, Expect=8e-42]} {RNA1509_5363} {RNA1310_11839} {RNA815_5371}

Mlig455_002304 {REF} {Length: 2481} {TRANSSPLICED} {Pfam: Cytochrome P450 [PF00067.24, score=324.8]} {Human: ENSG00000134716, CYP2J2, cytochrome P450 family 2 subfamily J member 2, [Score=194, Expect=3e-55]; ENSG00000138061, CYP1B1, cytochrome P450 family 1 subfamily B member 1, [Score=188, Expect=8e-53]} {Mouse: ENSMUSG00000003555, Cyp17a1, cytochrome P450, family 17, subfamily a, polypeptide 1, [RH, Score=197, Expect=2e-56]} {Dmel: FBgn0004959, phm, Peptidylglycine-alpha-hydroxylating monooxygenase, [Score=143, Expect=2e-36]} {Celegans: WBGene00016697, cyp-33C2, CYtochrome P450 family, [Score=160, Expect=3e-43]} {Smed: dd_Smed_v6_3919_0_1, dd_Smed_v6_3919_0_1, [Score=156, Expect=8e-42]} {RNA1509_5363} {RNA1310_11839, RNA1509_5363} {RNA1509_5363, RNA815_5371}
2. MligTC455_06092 762 15.88 Mlig455_069915

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.940

2.732 - - - 0.955 0.859 0.918 Mlig455_069915 {REF} {Length: 3038} {Pfam: Otopetrin [PF03189.15, score=32.6]} {RNA1509_10108} {RNA1310_8141, RNA1509_10108} {RNA1509_10108, RNA815_2847.1}
3. MligTC455_29557 797 16.6 Mlig455_040172

Neo: -

Age: logFC(26M/2M)=-0.290

TMEM67 2.59 0.952 0.788 - - 0.850 - Mlig455_040172 {REF} {Length: 3157} {Pfam: Meckelin (Transmembrane protein 67) [PF09773.11, score=669.0]} {Human: ENSG00000164953, TMEM67, transmembrane protein 67, [Score=437, Expect=1e-140]} {Mouse: ENSMUSG00000049488, Tmem67, transmembrane protein 67, [Score=429, Expect=1e-136]} {Dmel: FBgn0038814, CG15923, [Score=139, Expect=9e-34]} {Celegans: WBGene00018042, mks-3, MecKel-Gruber Syndrome (MKS) homolog, [Score=278, Expect=2e-81]} {Smed: dd_Smed_v6_7765_0_1, dd_Smed_v6_7765_0_1, [Score=476, Expect=9e-156]} {RNA1509_26795, RNA1509_3205, RNA1509_40554} {RNA1310_2827.1, RNA1509_26795, RNA1509_40554} {RNA1509_26795, RNA1509_40554, RNA815_833}
4. MligTC455_35886 941 19.59 Mlig455_013877

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.313

Region-specific R4: 1.689

Region-enriched R4: 1.129/0.00623

Regeneration-downregulated R4: -1.365

Regeneration-depleted R4: -1.365

HRASLS2 2.521 - - 0.704 0.978 - 0.839 Mlig455_013877 {REF} {Length: 1953} {Pfam: Lecithin retinol acyltransferase [PF04970.15, score=65.8]} {Human: ENSG00000133328, HRASLS2, HRAS like suppressor 2, [Score=52.4, Expect=7e-08]} {Mouse: ENSMUSG00000028003, Lrat, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase), [RH, Score=50.4, Expect=5e-07]} {RNA1509_5071, RNA1509_56927} {RNA1310_21690, RNA1509_56927} {RNA1509_56927, RNA815_8872}
5. MligTC455_44049 683 14.24 Mlig455_056686

Neo: -

Age: logFC(26M/2M)=0.180

Region-enriched R4: 1.577/0.00572

2.438 - 0.726 - 0.746 - 0.966 Mlig455_056686 {REF} {Length: 2385} {Pfam: Multi-glycosylated core protein 24 (MGC-24), sialomucin [PF05283.13, score=33.2]} {Dmel: FBgn0045823, vsg, visgun, [Score=47.0, Expect=2e-06]} {Smed: dd_Smed_v6_828_0_1, dd_Smed_v6_828_0_1, [Score=49.7, Expect=8e-09]} {RNA1509_14879, RNA1509_9381} {RNA1310_34958.1, RNA1509_9381} {RNA1509_9381, RNA815_6770.2}
6. MligTC455_37310 188 3.92 Mlig455_043635

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=3.872

ARRDC4 2.434 - - - 0.954 0.751 0.729 Mlig455_043635 {REF} {Length: 2231} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=81.3]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=44.1]} {Human: ENSG00000140450, ARRDC4, arrestin domain containing 4, [Score=70.1, Expect=3e-12]; ENSG00000197070, ARRDC1, arrestin domain containing 1, [Score=67.8, Expect=2e-11]} {Mouse: ENSMUSG00000026972, Arrdc1, arrestin domain containing 1, [Score=63.5, Expect=3e-10]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=78.2, Expect=2e-15]} {Celegans: WBGene00018060, arrd-18, ARRestin Domain protein, [Score=65.5, Expect=4e-11]} {RNA1509_13418} {RNA1310_36821} {RNA815_11006.1}
7. MligTC455_31914 588 12.26 Mlig455_062954

Neo: -

Age: logFC(26M/2M)=-0.527

1.849 - - - 0.898 0.951 - Mlig455_062954 {REF} {Length: 4090} {RNA1509_13632} {RNA1310_13490, RNA1509_13632} {RNA1509_13632, RNA815_5417.1}
8. MligTC455_16002 752 15.67 Mlig455_062545

Neo: -

Age: -

TTC16 1.813 - - 0.967 - 0.846 - Mlig455_062545 {REF} {Length: 2280} {TRANSSPLICED} {Pfam: Tetratricopeptide repeat [PF07719.19, score=82.7]; Tetratricopeptide repeat [PF00515.30, score=64.9]; TPR repeat [PF13414.8, score=58.1]; Tetratricopeptide repeat [PF13432.8, score=57.0]; Tetratricopeptide repeat [PF13181.8, score=56.4]; Tetratricopeptide repeat [PF13428.8, score=54.2]; Tetratricopeptide repeat [PF14559.8, score=42.2]; Tetratricopeptide repeat [PF13424.8, score=41.4]; Tetratricopeptide repeat [PF13371.8, score=32.2]; Tetratricopeptide repeat [PF13176.8, score=31.2]; Tetratricopeptide repeat [PF13431.8, score=24.0]; NMDA receptor-regulated protein 1 [PF12569.10, score=23.7]; Tetratricopeptide repeat [PF13174.8, score=21.3]; Unstructured region C-term to UIM in Ataxin3 [PF16619.7, score=19.2]} {Human: ENSG00000167094, TTC16, tetratricopeptide repeat domain 16, [RH, Score=291, Expect=3e-86]} {Mouse: ENSMUSG00000039021, Ttc16, tetratricopeptide repeat domain 16, [RH, Score=295, Expect=9e-89]} {Celegans: WBGene00000500, chn-1, C-term of Hsp70-iNteracting protein (CHIP family); Hsp70-interacting protein, [Score=50.8, Expect=1e-06]} {Smed: dd_Smed_v6_11894_0_1, dd_Smed_v6_11894_0_1, [RH, Score=447, Expect=1e-147]} {RNA1509_9009} {RNA1310_10645.1, RNA1509_9009} {RNA1509_9009, RNA815_3627}
9. MligTC455_16955 1687 35.15 Mlig455_051000

Neo: -

Age: Down-Up-Up

PLA2G7 1.776 - - - - 0.822 0.954 Mlig455_051000 {REF} {Length: 1559} {TRANSSPLICED} {Pfam: Platelet-activating factor acetylhydrolase, isoform II [PF03403.15, score=213.8]; alpha/beta hydrolase fold [PF00561.22, score=28.3]; Alpha/beta hydrolase family [PF12697.9, score=26.6]; Serine aminopeptidase, S33 [PF12146.10, score=25.3]; Chlorophyllase enzyme [PF12740.9, score=20.4]} {Human: ENSG00000146070, PLA2G7, phospholipase A2 group VII, [RH, Score=171, Expect=1e-48]} {Mouse: ENSMUSG00000037366, Pafah2, platelet-activating factor acetylhydrolase 2, [RH, Score=163, Expect=5e-46]; ENSMUSG00000023913, Pla2g7, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), [RH, Score=158, Expect=1e-43]} {Celegans: WBGene00003906, paf-1, PAF-1; PAF-acetylhydrolase, [RH, Score=142, Expect=2e-38]} {RNA1509_16678, RNA1509_21980} {RNA1310_21439.1, RNA1509_16678, RNA1509_21980} {RNA1509_16678, RNA1509_21980, RNA815_19873}
10. MligTC455_24629 2352 49 Mlig455_048991, Mlig455_049008

Neo: -

Age: logFC(26M/2M)=0.306

TTN 1.767 - - 0.954 - 0.813 -

Mlig455_048991 {REF} {Length: 4675} {Pfam: RhoGEF domain [PF00621.22, score=28.1]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=22.5]} {Dmel: FBgn0023172, RhoGEF2, Rho guanine nucleotide exchange factor 2, [Score=58.2, Expect=6e-08]} {RNA1509_7176} {RNA1310_1343.1} {RNA815_10881}

Mlig455_049008 {REF} {Length: 4681} {Pfam: RhoGEF domain [PF00621.22, score=28.1]; Phorbol esters/diacylglycerol binding domain (C1 domain) [PF00130.24, score=22.5]} {Human: ENSG00000155657, TTN, titin, [Score=51.6, Expect=1e-05]} {Dmel: FBgn0023172, RhoGEF2, Rho guanine nucleotide exchange factor 2, [Score=57.0, Expect=1e-07]} {RNA1509_7176} {RNA1310_1343.1} {RNA815_10881}
11. MligTC455_47290 272 5.67 Mlig455_068255

Neo: -

Age: logFC(26M/2M)=0.320

LENG9 1.756 0.978 - - - - 0.778 Mlig455_068255 {REF} {Length: 3500} {TRANSSPLICED} {Pfam: AKAP7 2'5' RNA ligase-like domain [PF10469.11, score=109.5]; MJ1316 RNA cyclic group end recognition domain [PF04457.14, score=83.3]; 2'-5' RNA ligase superfamily [PF13563.8, score=23.8]; LigT like Phosphoesterase [PF02834.18, score=22.3]} {Human: ENSG00000273574, LENG9, leukocyte receptor cluster member 9, [RH, Score=100, Expect=7e-22]; ENSG00000274495, LENG9, leukocyte receptor cluster member 9, [RH, Score=100, Expect=7e-22]} {Mouse: ENSMUSG00000043432, Leng9, leukocyte receptor cluster (LRC) member 9, [RH, Score=116, Expect=3e-27]} {RNA1509_50306} {RNA1310_7334.1} {RNA815_22553}
12. MligTC455_15996 396 8.26 Mlig455_064976, Mlig455_066809

Neo: -

Age: -

ARHGEF17 1.733 0.970 0.763 - - - -

Mlig455_064976 {REF} {Length: 4968} {Pfam: WD40 repeated domain [PF19056.2, score=146.7]; RhoGEF domain [PF00621.22, score=136.4]} {Human: ENSG00000110237, ARHGEF17, Rho guanine nucleotide exchange factor 17, [Score=233, Expect=6e-61]} {Mouse: ENSMUSG00000032875, Arhgef17, Rho guanine nucleotide exchange factor (GEF) 17, [Score=239, Expect=3e-63]} {Dmel: FBgn0262562, CG43102, [RH, Score=520, Expect=4e-156]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [RH, Score=240, Expect=2e-64]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [RH, Score=713, Expect=0.0]} {RNA1509_36394} {RNA1310_6117.1} {RNA815_14497}

Mlig455_066809 {REF} {Length: 5061} {Pfam: WD40 repeated domain [PF19056.2, score=146.7]; RhoGEF domain [PF00621.22, score=125.9]} {Human: ENSG00000110237, ARHGEF17, Rho guanine nucleotide exchange factor 17, [RH, Score=266, Expect=2e-71]} {Mouse: ENSMUSG00000032875, Arhgef17, Rho guanine nucleotide exchange factor (GEF) 17, [RH, Score=264, Expect=1e-70]} {Dmel: FBgn0262562, CG43102, [RH, Score=503, Expect=8e-150]} {Celegans: WBGene00019832, osg-1, Rho guanine nucleotide exchange factor osg-1, [Score=224, Expect=3e-59]} {Smed: dd_Smed_v6_2922_0_1, dd_Smed_v6_2922_0_1, [RH, Score=691, Expect=0.0]} {RNA1509_36394} {RNA1310_6117.1} {RNA815_23184}
13. MligTC455_50508 947 19.73 Mlig455_067809

Neo: -

Age: Down-Up-Up

UBE2Z 1.722 0.967 - - - - 0.755 Mlig455_067809 {REF} {Length: 1426} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=80.1]} {Human: ENSG00000159202, UBE2Z, ubiquitin conjugating enzyme E2 Z, [Score=124, Expect=2e-32]} {Mouse: ENSMUSG00000014349, Ube2z, ubiquitin-conjugating enzyme E2Z, [Score=124, Expect=1e-32]} {Dmel: FBgn0266717, Bruce, BIR repeat containing ubiquitin-conjugating enzyme, [Score=75.1, Expect=1e-14]} {Celegans: WBGene00006712, ubc-17, Probable ubiquitin-conjugating enzyme protein 17, [Score=83.2, Expect=1e-17]} {Smed: dd_Smed_v6_2721_0_1, dd_Smed_v6_2721_0_1, [Score=127, Expect=6e-35]} {RNA1509_23001} {RNA1310_23166.1} {RNA815_9851.1}
14. MligTC455_39220 941 19.61 Mlig455_033864

Neo: -

Age: -

1.72 - - - 0.765 0.955 - Mlig455_033864 {REF} {Length: 2994} {TRANSSPLICED} {Pfam: FAM181 [PF15238.8, score=27.8]} {RNA1509_26930, RNA1509_8505} {RNA1310_30346.1, RNA1509_26930} {RNA1509_26930, RNA815_67.1}
15. MligTC455_43109 491 10.23 Mlig455_029599

Neo: -

Age: -

ARRDC2 1.711 0.957 - - 0.754 - - Mlig455_029599 {REF} {Length: 1947} {Pfam: Arrestin (or S-antigen), N-terminal domain [PF00339.31, score=67.4]; Arrestin (or S-antigen), C-terminal domain [PF02752.24, score=58.1]} {Human: ENSG00000105643, ARRDC2, arrestin domain containing 2, [Score=100, Expect=1e-22]} {Mouse: ENSMUSG00000110906, Arrdc2, arrestin domain containing 2, [Score=97.1, Expect=8e-22]; ENSMUSG00000002910, Arrdc2, arrestin domain containing 2, [Score=97.1, Expect=8e-22]} {Dmel: FBgn0035103, Vdup1, Vitamin D[[3]] up-regulated protein 1, [Score=90.5, Expect=5e-20]} {Celegans: WBGene00011732, arrd-17, Arrestin domain-containing protein 17, [Score=84.3, Expect=1e-17]} {Smed: dd_Smed_v6_8715_0_1, dd_Smed_v6_8715_0_1, [Score=55.8, Expect=2e-08]} {RNA1509_45476} {RNA1310_16251} {RNA815_9075}
16. MligTC455_32456 153 3.19 Mlig455_034353

Neo: -

Age: -

ELAVL3 1.708 0.958 - - - - 0.750 Mlig455_034353 {REF} {Length: 5138} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=279.8]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=27.7]; Occluded RNA-recognition motif [PF16842.7, score=27.3]; Nup53/35/40-type RNA recognition motif [PF05172.15, score=23.3]} {Human: ENSG00000196361, ELAVL3, ELAV like RNA binding protein 3, [Score=191, Expect=7e-54]; ENSG00000162374, ELAVL4, ELAV like RNA binding protein 4, [Score=191, Expect=9e-54]; ENSG00000107105, ELAVL2, ELAV like RNA binding protein 2, [Score=188, Expect=9e-53]; ENSG00000066044, ELAVL1, ELAV like RNA binding protein 1, [Score=185, Expect=3e-52]} {Mouse: ENSMUSG00000003410, Elavl3, ELAV like RNA binding protein 3, [Score=192, Expect=3e-54]; ENSMUSG00000028546, Elavl4, ELAV like RNA binding protein 4, [Score=191, Expect=7e-54]; ENSMUSG00000008489, Elavl2, ELAV like RNA binding protein 1, [Score=188, Expect=7e-53]; ENSMUSG00000040028, Elavl1, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R), [Score=187, Expect=3e-53]} {Dmel: FBgn0086675, fne, found in neurons, [Score=189, Expect=9e-54]} {Celegans: WBGene00001368, exc-7, [Score=120, Expect=1e-28]} {Smed: dd_Smed_v6_11311_0_2, dd_Smed_v6_11311_0_2, [Score=112, Expect=2e-26]} {RNA1509_13713} {RNA1310_8489, RNA1509_13713} {RNA1509_13713, RNA815_12096}
17. MligTC455_22412 271 5.65 Mlig455_057681, Mlig455_059990

Neo: -

Age: Down-Up-Up

1.705 0.956 - - - - 0.749

Mlig455_057681 {REF} {Length: 2023} {RNA1509_30929} {RNA1310_27672} {RNA815_26534}

Mlig455_059990 {REF} {Length: 2023} {RNA1509_30929} {RNA1310_27672} {RNA815_26534}
18. MligTC455_34010 204 4.26 Mlig455_024028, Mlig455_024093

Neo: -

Age: Up-Down-Down

KCNC1 1.702 0.970 - - - - 0.732

Mlig455_024028 {REF} {Length: 3896} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734}

Mlig455_024093 {REF} {Length: 3992} {Pfam: Ion transport protein [PF00520.33, score=148.2]; BTB/POZ domain [PF02214.24, score=101.1]; Ion channel [PF07885.18, score=44.0]} {Human: ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [RH, Score=426, Expect=1e-141]; ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [RH, Score=424, Expect=2e-140]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [RH, Score=407, Expect=1e-133]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [RH, Score=426, Expect=5e-142]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [RH, Score=411, Expect=2e-135]; ENSMUSG00000062785, Kcnc3, potassium voltage gated channel, Shaw-related subfamily, member 3, [RH, Score=408, Expect=1e-132]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [RH, Score=710, Expect=0.0]} {Celegans: WBGene00004793, shw-3, SHaW family of potassium channels; Voltage-gated K+ channel isoform 1, [RH, Score=590, Expect=0.0]} {Smed: dd_Smed_v6_9740_0_1, dd_Smed_v6_9740_0_1, [RH, Score=689, Expect=0.0]} {RNA1509_54375} {RNA1310_15083.2} {RNA815_13734}
19. MligTC455_21030 293 6.09 Mlig455_002272

Neo: -

Age: Down-Down-Up

1.701 - - - - 0.743 0.958 Mlig455_002272 {REF} {Length: 2822} {TRANSSPLICED} {RNA1509_51769} {RNA1310_12011} {RNA815_30830}
20. MligTC455_21032 654 13.63 Mlig455_054554, Mlig455_066337

Neo: -

Age: -

1.701 - - - - 0.737 0.964

Mlig455_054554 {REF} {Length: 652} {NoTransDecoderORF} {RNA1509_36765} {RNA1310_8260.1} {RNA815_20588}

Mlig455_066337 {REF} {Length: 463} {NoTransDecoderORF} {RNA1509_36765} {RNA1310_8260.1} {RNA815_20588}
21. MligTC455_16150 267 5.56 Mlig455_057692

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.781

KLHDC8A 1.675 0.959 - - 0.716 - - Mlig455_057692 {REF} {Length: 1684} {Pfam: Kelch motif [PF13964.8, score=56.8]; Kelch motif [PF01344.27, score=52.7]; Kelch motif [PF07646.17, score=36.4]; Galactose oxidase, central domain [PF13418.8, score=35.1]; Kelch motif [PF13854.8, score=27.6]} {Human: ENSG00000162873, KLHDC8A, kelch domain containing 8A, [Score=58.5, Expect=3e-09]} {Mouse: ENSMUSG00000042115, Klhdc8a, kelch domain containing 8A, [Score=63.5, Expect=1e-10]} {Smed: dd_Smed_v6_14507_0_1, dd_Smed_v6_14507_0_1, [RH, Score=209, Expect=3e-63]} {RNA1509_58319, RNA1509_58644} {RNA1310_20213, RNA1509_58319, RNA1509_58644} {RNA1509_58319, RNA1509_58644, RNA815_8052}
22. MligTC455_38787 26 0.53 Mlig455_063549

Neo: -

Age: -

0.978 0.978 - - - - - Mlig455_063549 {REF} {Length: 186} {NoTransDecoderORF} {tRNA: His(GTG), score=60.8} {RNA1509_11551}
23. MligTC455_46746 155 3.22 Mlig455_050385

Neo: -

Age: -

ANKRD11 0.971 0.971 - - - - - Mlig455_050385 {REF} {Length: 5095} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=64.7]; Ankyrin repeats (many copies) [PF13637.8, score=63.7]; Ankyrin repeats (many copies) [PF13857.8, score=61.1]; Ankyrin repeat [PF00023.32, score=55.4]; Ankyrin repeat [PF13606.8, score=44.6]} {Human: ENSG00000167522, ANKRD11, ankyrin repeat domain 11, [RH, Score=136, Expect=2e-31]} {Mouse: ENSMUSG00000035569, Ankrd11, ankyrin repeat domain 11, [RH, Score=137, Expect=8e-32]; ENSMUSG00000034647, Ankrd12, ankyrin repeat domain 12, [RH, Score=132, Expect=2e-30]} {Dmel: FBgn0036305, CG10984, [RH, Score=105, Expect=1e-22]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=91.7, Expect=4e-18]} {Smed: dd_Smed_v6_9297_0_1, dd_Smed_v6_9297_0_1, [RH, Score=154, Expect=4e-38]} {RNA1509_17750} {RNA1310_3406, RNA1509_17750} {RNA1509_17750, RNA815_33283}
24. MligTC455_22214 237 4.94 Mlig455_019333, Mlig455_019447

Neo: -

Age: -

NRG2 0.97 0.970 - - - - -

Mlig455_019333 {REF} {Length: 4291} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.7]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.0]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=86.7, Expect=8e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=81.3, Expect=2e-15]} {Dmel: FBgn0005666, bt, bent, [Score=52.0, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}

Mlig455_019447 {REF} {Length: 4242} {Pfam: Immunoglobulin I-set domain [PF07679.18, score=50.5]; Immunoglobulin domain [PF13927.8, score=44.8]; Immunoglobulin domain [PF00047.27, score=43.9]; Immunoglobulin domain [PF13895.8, score=22.1]; CD80-like C2-set immunoglobulin domain [PF08205.14, score=18.6]} {Human: ENSG00000158458, NRG2, neuregulin 2, [RH, Score=88.6, Expect=2e-17]} {Mouse: ENSMUSG00000060275, Nrg2, neuregulin 2, [RH, Score=83.2, Expect=7e-16]} {Dmel: FBgn0005666, bt, bent, [Score=52.4, Expect=2e-06]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=51.2, Expect=3e-06]} {Smed: dd_Smed_v6_15129_0_1, dd_Smed_v6_15129_0_1, [Score=55.1, Expect=9e-08]} {RNA1509_54517} {RNA1310_8322} {RNA815_13786}
25. MligTC455_15992 222 4.63 Mlig455_062899

Neo: -

Age: Up-Up-Down

0.968 0.968 - - - - - Mlig455_062899 {REF} {Length: 2159} {RNA1509_41203} {RNA1310_21857} {RNA815_12774}
26. MligTC455_34393 332 6.91 Mlig455_000981, Mlig455_037508

Neo: -

Age: -

AC093830.1 0.967 0.967 - - - - -

Mlig455_000981 {REF} {Length: 3619} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=184.0]} {Human: ENSG00000262505, AC093830.1, acid sensing ion channel subunit family member 5, [Score=53.1, Expect=1e-06]; ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=52.8, Expect=2e-06]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=68.9, Expect=1e-11]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.4, Expect=1e-06]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=84.3, Expect=1e-16]} {RNA1509_28049} {RNA1310_8320.2} {RNA815_4456}

Mlig455_037508 {REF} {Length: 3555} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=184.0]} {Human: ENSG00000262505, AC093830.1, acid sensing ion channel subunit family member 5, [Score=53.1, Expect=1e-06]; ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=52.8, Expect=2e-06]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=69.3, Expect=9e-12]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=52.0, Expect=1e-06]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=84.7, Expect=8e-17]} {RNA1509_28049} {RNA1310_8320.1} {RNA815_4456}
27. MligTC455_19712 82 1.7 Mlig455_000384

Neo: -

Age: -

0.966 0.966 - - - - - Mlig455_000384 {REF} {Length: 1367} {NoTransDecoderORF} {RNA1310_88029.2} {RNA815_48482}
28. MligTC455_37792 210 4.38 Mlig455_024774

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.926

Region-enriched R2: 6.055/0.00271

PKD1L2 0.966 0.966 - - - - - Mlig455_024774 {REF} {Length: 6374} {Pfam: Polycystin cation channel [PF08016.14, score=224.6]; PLAT/LH2 domain [PF01477.25, score=66.8]; Ion transport protein [PF00520.33, score=30.8]} {Human: ENSG00000166473, PKD1L2, polycystin 1 like 2 (gene/pseudogene), [Score=179, Expect=9e-45]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=187, Expect=3e-47]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=109, Expect=1e-23]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [Score=187, Expect=2e-47]} {Smed: dd_Smed_v6_13975_0_1, dd_Smed_v6_13975_0_1, [Score=902, Expect=0.0]} {RNA1509_46134} {RNA1310_488} {RNA815_1711}
29. MligTC455_34394 250 5.2 Mlig455_037589

Neo: -

Age: logFC(26M/2M)=-0.433

AC093830.1 0.965 0.965 - - - - - Mlig455_037589 {REF} {Length: 8689} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=185.0]} {Human: ENSG00000262505, AC093830.1, acid sensing ion channel subunit family member 5, [Score=54.3, Expect=6e-07]; ENSG00000256394, ASIC5, acid sensing ion channel subunit family member 5, [Score=53.9, Expect=1e-06]} {Mouse: ENSMUSG00000028008, Asic5, acid-sensing (proton-gated) ion channel family member 5, [Score=70.5, Expect=4e-12]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [Score=51.6, Expect=2e-06]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=85.9, Expect=4e-17]} {RNA1509_28049} {RNA1310_8320.1} {RNA815_4456}
30. MligTC455_04268 205 4.26 Mlig455_020034

Neo: -

Age: -

Region-enriched R5: 2.401/0.04505

0.964 0.964 - - - - - Mlig455_020034 {REF} {Length: 2636} {Pfam: Tetraspanin family [PF00335.22, score=70.2]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=28.8]; Inhibitor of Apoptosis domain [PF00653.23, score=20.2]} {Smed: dd_Smed_v6_546_0_1, dd_Smed_v6_546_0_1, [Score=47.4, Expect=9e-06]} {RNA1509_7464} {RNA1310_34864} {RNA815_16518}
31. MligTC455_19493 722 15.04 Mlig455_019064, Mlig455_064304, Mlig455_064339

Neo: -

Age: -

ERI3 0.961 - - - - - 0.961

Mlig455_019064 {REF} {Length: 1504} {Pfam: Exonuclease [PF00929.26, score=114.4]} {Human: ENSG00000117419, ERI3, ERI1 exoribonuclease family member 3, [Score=228, Expect=1e-73]} {Mouse: ENSMUSG00000033423, Eri3, exoribonuclease 3, [Score=228, Expect=1e-73]} {Dmel: FBgn0265192, Snp, Snipper, [RH, Score=130, Expect=5e-37]} {Celegans: WBGene00019825, R02D3.8, [RH, Score=175, Expect=4e-54]} {Smed: dd_Smed_v6_9578_0_1, dd_Smed_v6_9578_0_1, [Score=100, Expect=6e-25]} {RNA1509_40848} {RNA1310_34116} {RNA815_16548}

Mlig455_064304 {REF} {Length: 1587} {TRANSSPLICED} {Pfam: Exonuclease [PF00929.26, score=116.0]} {Human: ENSG00000117419, ERI3, ERI1 exoribonuclease family member 3, [RH, Score=246, Expect=9e-81]} {Mouse: ENSMUSG00000033423, Eri3, exoribonuclease 3, [RH, Score=244, Expect=2e-80]} {Dmel: FBgn0265192, Snp, Snipper, [RH, Score=134, Expect=5e-38]} {Celegans: WBGene00019825, R02D3.8, [RH, Score=184, Expect=1e-57]} {Smed: dd_Smed_v6_9578_0_1, dd_Smed_v6_9578_0_1, [Score=110, Expect=2e-28]} {RNA1509_40848} {RNA1310_34116} {RNA815_16548}

Mlig455_064339 {REF} {Length: 1553} {Pfam: Exonuclease [PF00929.26, score=116.0]} {Human: ENSG00000117419, ERI3, ERI1 exoribonuclease family member 3, [RH, Score=247, Expect=4e-81]} {Mouse: ENSMUSG00000033423, Eri3, exoribonuclease 3, [RH, Score=246, Expect=8e-81]} {Dmel: FBgn0265192, Snp, Snipper, [RH, Score=134, Expect=3e-38]} {Celegans: WBGene00019825, R02D3.8, [RH, Score=182, Expect=5e-57]} {Smed: dd_Smed_v6_9578_0_1, dd_Smed_v6_9578_0_1, [Score=110, Expect=2e-28]} {RNA1509_40848} {RNA1310_34116} {RNA815_16548}
32. MligTC455_19713 123 2.56 Mlig455_067957

Neo: -

Age: logFC(26M/2M)=0.481

0.957 0.957 - - - - - Mlig455_067957 {REF} {Length: 3388} {Pfam: Methyltransferase FkbM domain [PF05050.14, score=26.1]} {Smed: dd_Smed_v6_25359_0_1, dd_Smed_v6_25359_0_1, [Score=80.5, Expect=4e-17]} {RNA1310_22838} {RNA815_48482}
33. MligTC455_41148 341 7.1 Mlig455_060971

Neo: -

Age: -

0.956 0.956 - - - - - Mlig455_060971 {REF} {Length: 1945} {TRANSSPLICED} {RNA1310_18710.1} {RNA815_9967}
34. MligTC455_45222 576 11.99 Mlig455_003815

Neo: -

Age: Up-Down-Up

USP40 0.954 0.954 - - - - - Mlig455_003815 {REF} {Length: 4401} {TRANSSPLICED} {Pfam: Ubiquitin carboxyl-terminal hydrolase [PF00443.31, score=135.1]; Ubiquitin carboxyl-terminal hydrolase [PF13423.8, score=59.5]} {Human: ENSG00000085982, USP40, ubiquitin specific peptidase 40, [RH, Score=325, Expect=3e-92]} {Mouse: ENSMUSG00000005501, Usp40, ubiquitin specific peptidase 40, [RH, Score=315, Expect=1e-88]} {Dmel: FBgn0016756, Usp47, Ubiquitin specific protease 47, [Score=161, Expect=1e-39]} {Celegans: WBGene00011507, T05H10.1, Ubiquitin carboxyl-terminal hydrolase, [RH, Score=178, Expect=5e-45]} {Smed: dd_Smed_v6_7459_0_1, dd_Smed_v6_7459_0_1, [Score=166, Expect=2e-41]} {RNA1509_2877, RNA1509_48092} {RNA1310_1562.1, RNA1509_48092} {RNA1509_48092, RNA815_508}
35. MligTC455_30989 850 17.72 Mlig455_004138, Mlig455_060480, Mlig455_060509

Neo: -

Age: Down-Up-Up

Region-enriched R7: 2.352/0.02063

0.953 0.953 - - - - -

Mlig455_004138 {REF} {Length: 2615} {TRANSSPLICED} {RNA1509_32375} {RNA1310_14075} {RNA815_28378}

Mlig455_060480 {REF} {Length: 2749} {TRANSSPLICED} {RNA1509_32375} {RNA1310_14075} {RNA815_28378}

Mlig455_060509 {REF} {Length: 2671} {TRANSSPLICED} {RNA1509_12588, RNA1509_32375} {RNA1310_18669, RNA1509_12588} {RNA1509_12588, RNA815_28378}
36. MligTC455_49340 237 4.95 Mlig455_049270

Neo: -

Age: -

METTL15 0.953 0.953 - - - - - Mlig455_049270 {REF} {Length: 2647} {tRNA: Val(TAC),pseudo, score=25.8} {Pfam: MraW methylase family [PF01795.21, score=232.1]} {Human: ENSG00000169519, METTL15, methyltransferase like 15, [RH, Score=232, Expect=5e-72]} {Mouse: ENSMUSG00000057234, Mettl15, methyltransferase like 15, [RH, Score=232, Expect=5e-72]} {Dmel: FBgn0037822, CG14683, [RH, Score=224, Expect=5e-70]} {Smed: dd_Smed_v6_6390_0_6, dd_Smed_v6_6390_0_6, [RH, Score=204, Expect=1e-62]} {RNA1509_21751} {RNA1310_18813} {RNA815_16808}
37. MligTC455_50062 275 5.73 Mlig455_041829

Neo: -

Age: -

DPP8 0.951 0.951 - - - - - Mlig455_041829 {REF} {Length: 3294} {TRANSSPLICED} {Pfam: Prolyl oligopeptidase family [PF00326.23, score=157.9]; Dipeptidyl peptidase IV (DPP IV) N-terminal region [PF00930.23, score=144.2]} {Human: ENSG00000074603, DPP8, dipeptidyl peptidase 8, [RH, Score=405, Expect=3e-127]} {Mouse: ENSMUSG00000032393, Dpp8, dipeptidylpeptidase 8, [RH, Score=409, Expect=2e-128]} {Dmel: FBgn0039240, CG3744, [RH, Score=374, Expect=2e-113]} {Celegans: WBGene00001056, dpf-3, Dipeptidyl Peptidase Four (IV) family, [Score=257, Expect=1e-72]} {Smed: dd_Smed_v6_8398_0_1, dd_Smed_v6_8398_0_1, [RH, Score=292, Expect=5e-86]} {RNA1509_29851, RNA1509_56960} {RNA1310_4366, RNA1509_29851, RNA1509_56960} {RNA1509_29851, RNA1509_56960, RNA815_1863}
38. MligTC455_17355 454 9.46 Mlig455_042392

Neo: -

Age: -

0.95 0.950 - - - - - Mlig455_042392 {REF} {Length: 1844} {RNA1509_44829, RNA1509_47909} {RNA1310_36451, RNA1509_44829, RNA1509_47909} {RNA1509_44829, RNA1509_47909, RNA815_18418}
39. MligTC455_42624 302 6.29 Mlig455_058165, Mlig455_058219

Neo: -

Age: logFC(26M/2M)=-0.485

GAS2L1 0.95 - - - - - 0.950

Mlig455_058165 {REF} {Length: 3338} {Pfam: Growth-Arrest-Specific Protein 2 Domain [PF02187.19, score=105.3]; Calponin homology (CH) domain [PF00307.33, score=29.5]} {Human: ENSG00000185340, GAS2L1, growth arrest specific 2 like 1, [RH, Score=223, Expect=2e-64]} {Mouse: ENSMUSG00000034201, Gas2l1, growth arrest-specific 2 like 1, [RH, Score=258, Expect=1e-77]} {Dmel: FBgn0029881, pigs, pickled eggs, [Score=246, Expect=2e-71]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=77.0, Expect=2e-14]} {Smed: dd_Smed_v6_8154_0_1, dd_Smed_v6_8154_0_1, [RH, Score=272, Expect=4e-85]} {RNA1509_28378} {RNA1310_8988.1} {RNA815_19449}

Mlig455_058219 {REF} {Length: 2846} {Pfam: Growth-Arrest-Specific Protein 2 Domain [PF02187.19, score=105.3]; Calponin homology (CH) domain [PF00307.33, score=29.5]} {Human: ENSG00000185340, GAS2L1, growth arrest specific 2 like 1, [RH, Score=223, Expect=2e-64]} {Mouse: ENSMUSG00000034201, Gas2l1, growth arrest-specific 2 like 1, [RH, Score=258, Expect=1e-77]} {Dmel: FBgn0029881, pigs, pickled eggs, [Score=247, Expect=1e-71]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=76.6, Expect=3e-14]} {Smed: dd_Smed_v6_8154_0_1, dd_Smed_v6_8154_0_1, [RH, Score=272, Expect=4e-85]} {RNA1509_28378} {RNA1310_8988.1} {RNA815_19449}

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