Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_44084 | 235 | 4.90 | Mlig455_011457 | Neo: - Age: - |
FLCN | Mlig455_011457 {REF} {Length: 5279} {TRANSSPLICED} {Pfam: Vesicle coat protein involved in Golgi to plasma membrane transport [PF11704.10, score=126.0]; Forkhead domain [PF00250.20, score=110.5]; Folliculin C-terminal domain [PF16692.7, score=107.0]} {Human: ENSG00000154803, FLCN, folliculin, [Score=209, Expect=1e-56]} {Mouse: ENSMUSG00000032633, Flcn, folliculin, [Score=208, Expect=1e-56]} {Dmel: FBgn0029504, CHES-1-like, Checkpoint suppressor 1-like, [RH, Score=139, Expect=1e-32]} {Celegans: WBGene00017699, flcn-1, F22D3.2 protein; FoLliCuliN, [RH, Score=97.1, Expect=3e-20]} {Smed: dd_Smed_v6_4329_0_2, dd_Smed_v6_4329_0_2, [Score=148, Expect=3e-37]} {RNA1509_11130, RNA1509_33195} {RNA1310_5404, RNA1509_33195} {RNA1509_33195, RNA815_1916} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.069 | 2.846 | 0.96728 | 1.00000 | |
RegionR2 | -0.144 | 2.846 | 0.85669 | 1.00000 | |
RegionR3 | 0.162 | 2.846 | 0.79366 | 1.00000 | |
RegionR4 | -0.15 | 2.846 | 0.84130 | 1.00000 | |
RegionR5 | 0.797 | 2.846 | 0.14857 | 0.40045 | |
RegionR6 | 0.443 | 2.846 | 0.50198 | 1.00000 | |
RegionR7 | 0.357 | 2.846 | 0.65790 | 1.00000 | |
RegionR8 | -1.533 | 2.846 | 0.23326 | 0.84755 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -5.468 | 2.846 | 0.31122 | 1.00000 | |
RegenerationR2 | 1.809 | 2.846 | 0.00411 | 0.09885 | |
RegenerationR3 | 0.985 | 2.846 | 0.15326 | 0.58302 | |
RegenerationR4 | 0.907 | 2.846 | 0.21707 | 0.66419 | |
RegenerationR5 | 0.769 | 2.846 | 0.21042 | 0.64416 | |
RegenerationR6 | -0.135 | 2.846 | 0.85381 | 1.00000 | |
RegenerationBL | -0.037 | 2.846 | 0.97291 | 1.00000 | |
RegenerationTP | 0.011 | 2.846 | 0.98935 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_44084 | 235 | 4.9 | Mlig455_011457 | Neo: - Age: - |
FLCN | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_011457 {REF} {Length: 5279} {TRANSSPLICED} {Pfam: Vesicle coat protein involved in Golgi to plasma membrane transport [PF11704.10, score=126.0]; Forkhead domain [PF00250.20, score=110.5]; Folliculin C-terminal domain [PF16692.7, score=107.0]} {Human: ENSG00000154803, FLCN, folliculin, [Score=209, Expect=1e-56]} {Mouse: ENSMUSG00000032633, Flcn, folliculin, [Score=208, Expect=1e-56]} {Dmel: FBgn0029504, CHES-1-like, Checkpoint suppressor 1-like, [RH, Score=139, Expect=1e-32]} {Celegans: WBGene00017699, flcn-1, F22D3.2 protein; FoLliCuliN, [RH, Score=97.1, Expect=3e-20]} {Smed: dd_Smed_v6_4329_0_2, dd_Smed_v6_4329_0_2, [Score=148, Expect=3e-37]} {RNA1509_11130, RNA1509_33195} {RNA1310_5404, RNA1509_33195} {RNA1509_33195, RNA815_1916} |
2. | MligTC455_50154 | 1013 | 21.11 | Mlig455_062175, Mlig455_062207 | Neo: - Age: - Region-enriched R5: 1.772/0.00870 Regeneration-upregulated BL: 1.960 Regeneration-enriched BL: 1.960 |
POU6F2 | 1.793 | - | - | - | 0.960 | - | 0.833 | Mlig455_062175 {REF} {Length: 3567} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=89.0]; Homeodomain [PF00046.31, score=61.4]} {Human: ENSG00000106536, POU6F2, POU class 6 homeobox 2, [Score=161, Expect=5e-42]} {Mouse: ENSMUSG00000009734, Pou6f2, POU domain, class 6, transcription factor 2, [Score=161, Expect=1e-42]} {Dmel: FBgn0261588, pdm3, pou domain motif 3, [Score=126, Expect=2e-30]} {Celegans: WBGene00000441, ceh-18, Homeobox protein ceh-18, [Score=109, Expect=3e-25]} {Smed: dd_Smed_v6_13010_0_1, dd_Smed_v6_13010_0_1, [Score=130, Expect=2e-32]} {RNA1509_33080, RNA1509_36081} {RNA1310_10551.1, RNA1509_33080, RNA1509_36081} {RNA1509_33080, RNA1509_36081, RNA815_8676} Mlig455_062207 {REF} {Length: 3563} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=89.0]; Homeodomain [PF00046.31, score=59.8]; Helix-turn-helix domain [PF13560.8, score=19.1]} {Human: ENSG00000106536, POU6F2, POU class 6 homeobox 2, [Score=159, Expect=1e-41]} {Mouse: ENSMUSG00000009734, Pou6f2, POU domain, class 6, transcription factor 2, [Score=159, Expect=7e-42]} {Dmel: FBgn0261588, pdm3, pou domain motif 3, [Score=125, Expect=7e-30]} {Celegans: WBGene00000441, ceh-18, Homeobox protein ceh-18, [Score=107, Expect=1e-24]} {Smed: dd_Smed_v6_13010_0_1, dd_Smed_v6_13010_0_1, [Score=130, Expect=2e-32]} {RNA1509_33080} {RNA1310_10551.1} {RNA815_8676} |
3. | MligTC455_05039 | 320 | 6.67 | Mlig455_035597 | Neo: - Age: Up-Down-Up |
KCND1 | 1.779 | - | - | - | 0.828 | - | 0.951 | Mlig455_035597 {REF} {Length: 3227} {TRANSSPLICED} {Pfam: Ion transport protein [PF00520.33, score=85.6]; Ion channel [PF07885.18, score=50.8]; Domain of unknown function (DUF3399) [PF11879.10, score=38.6]} {Human: ENSG00000102057, KCND1, potassium voltage-gated channel subfamily D member 1, [Score=261, Expect=3e-81]; ENSG00000184408, KCND2, potassium voltage-gated channel subfamily D member 2, [Score=258, Expect=2e-80]; ENSG00000171385, KCND3, potassium voltage-gated channel subfamily D member 3, [Score=249, Expect=1e-76]} {Mouse: ENSMUSG00000009731, Kcnd1, potassium voltage-gated channel, Shal-related family, member 1, [Score=261, Expect=3e-81]; ENSMUSG00000060882, Kcnd2, potassium voltage-gated channel, Shal-related family, member 2, [Score=258, Expect=4e-80]; ENSMUSG00000040896, Kcnd3, potassium voltage-gated channel, Shal-related family, member 3, [Score=249, Expect=7e-77]} {Dmel: FBgn0005564, Shal, Shaker cognate l, [Score=275, Expect=1e-87]} {Celegans: WBGene00022240, shl-1, SHaL family of potassium channels, [Score=270, Expect=2e-85]} {Smed: dd_Smed_v6_15876_0_1, dd_Smed_v6_15876_0_1, [Score=245, Expect=3e-75]} {RNA1509_13132} {RNA1310_4146.2} {RNA815_997} |
4. | MligTC455_52201 | 712 | 14.84 | Mlig455_000379 | Neo: Irradiation Age: Up-Down-Down Region-specific R4: 3.455 Region-enriched R4: 2.637/0.00000 Regeneration-downregulated R4: -1.839 Regeneration-depleted R4: -1.839 |
CHEK2 | 1.772 | - | - | - | 0.807 | - | 0.965 | Mlig455_000379 {REF} {Length: 2826} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=205.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=111.0]; FHA domain [PF00498.28, score=45.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=25.5]; Kinase-like [PF14531.8, score=19.4]; ABC1 atypical kinase-like domain [PF03109.18, score=19.2]} {Human: ENSG00000183765, CHEK2, checkpoint kinase 2, [Score=231, Expect=1e-67]} {Mouse: ENSMUSG00000029521, Chek2, checkpoint kinase 2, [Score=226, Expect=7e-66]} {Dmel: FBgn0019686, lok, loki, [Score=219, Expect=3e-64]} {Celegans: WBGene00000499, chk-2, Serine/threonine-protein kinase chk-2, [Score=174, Expect=1e-47]} {Smed: dd_Smed_v6_6620_0_1, dd_Smed_v6_6620_0_1, [Score=234, Expect=2e-70]} {RNA1509_3579} {RNA1310_6215, RNA1509_3579} {RNA1509_3579, RNA815_2071.1} |
5. | MligTC455_35453 | 76 | 1.58 | Mlig455_034810, Mlig455_047899, Mlig455_047985 | Neo: Germline Age: - Region-enriched R5: 2.528/0.04280 |
0.971 | - | - | - | - | 0.971 | - | Mlig455_034810 {REF} {Length: 182} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_121697} Mlig455_047899 {REF} {Length: 1196} {RNA1509_55040} {RNA1310_81175} {RNA815_38567} Mlig455_047985 {REF} {Length: 454} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_28413.1} {RNA815_41251} |
|
6. | MligTC455_47784 | 987 | 20.56 | Mlig455_042427, Mlig455_042482 | Neo: Irradiation Age: Down-Up-Down |
LPIN3 | 0.968 | - | - | - | - | - | 0.968 | Mlig455_042427 {REF} {Length: 3949} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=315.0]; lipin, N-terminal conserved region [PF04571.16, score=124.4]; Lipin/Ned1/Smp2 multi-domain protein middle domain [PF16876.7, score=88.2]} {Human: ENSG00000132793, LPIN3, lipin 3, [RH, Score=447, Expect=2e-144]} {Mouse: ENSMUSG00000027412, Lpin3, lipin 3, [RH, Score=441, Expect=3e-142]; ENSMUSG00000020593, Lpin1, lipin 1, [RH, Score=427, Expect=2e-136]} {Dmel: FBgn0263593, Lpin, Lipin, [RH, Score=355, Expect=2e-108]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [RH, Score=255, Expect=2e-73]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [RH, Score=407, Expect=1e-130]} {RNA1509_2460} {RNA1310_4371} {RNA815_2379.1} Mlig455_042482 {REF} {Length: 3845} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=315.1]; Lipin/Ned1/Smp2 multi-domain protein middle domain [PF16876.7, score=88.3]; lipin, N-terminal conserved region [PF04571.16, score=87.5]} {Human: ENSG00000132793, LPIN3, lipin 3, [RH, Score=414, Expect=5e-132]} {Mouse: ENSMUSG00000027412, Lpin3, lipin 3, [RH, Score=401, Expect=2e-127]} {Dmel: FBgn0263593, Lpin, Lipin, [RH, Score=355, Expect=6e-109]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [RH, Score=255, Expect=1e-73]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [RH, Score=407, Expect=2e-131]} {RNA1509_2460, RNA1509_26861, RNA1509_31871, RNA1509_42018} {RNA1310_4371, RNA1509_26861, RNA1509_31871, RNA1509_42018} {RNA1509_26861, RNA1509_31871, RNA1509_42018, RNA815_2379.1} |
7. | MligTC455_52372 | 288 | 5.99 | Mlig455_012761 | Neo: - Age: logFC(26M/2M)=-0.342 |
CEP89 | 0.965 | - | - | - | 0.965 | - | - | Mlig455_012761 {REF} {Length: 3139} {Pfam: Uncharacterised protein family (UPF0242) N-terminus [PF06785.13, score=23.6]} {Human: ENSG00000121289, CEP89, centrosomal protein 89, [RH, Score=113, Expect=1e-25]} {Mouse: ENSMUSG00000023072, Cep89, centrosomal protein 89, [RH, Score=106, Expect=2e-23]} {Smed: dd_Smed_v6_13073_0_1, dd_Smed_v6_13073_0_1, [RH, Score=80.5, Expect=1e-15]} {RNA1509_10380} {RNA1310_5262.1} {RNA815_3458.1} |
8. | MligTC455_35872 | 276 | 5.76 | Mlig455_039093 | Neo: - Age: Up-Up-Down |
0.964 | - | - | - | - | - | 0.964 | Mlig455_039093 {REF} {Length: 2636} {Pfam: Homeodomain-like domain [PF13384.8, score=26.2]; Helix-turn-helix domain [PF13518.8, score=25.9]} {RNA1509_48694} {RNA1310_48256} {RNA815_5960} | |
9. | MligTC455_41881 | 799 | 16.64 | Mlig455_011980, Mlig455_068626 | Neo: - Age: - |
FGFR1OP | 0.96 | - | - | - | - | - | 0.960 | Mlig455_011980 {REF} {Length: 2999} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=38.9]; LisH [PF16045.7, score=17.6]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=101, Expect=4e-23]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=99.4, Expect=2e-22]} {Smed: dd_Smed_v6_5371_0_1, dd_Smed_v6_5371_0_1, [Score=58.2, Expect=3e-09]} {RNA1509_14615} {RNA1310_13253.1} {RNA815_34617.1} Mlig455_068626 {REF} {Length: 2876} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=39.1]; LisH [PF16045.7, score=17.8]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=104, Expect=3e-24]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=99.4, Expect=1e-22]} {Smed: dd_Smed_v6_5371_0_2, dd_Smed_v6_5371_0_2, [Score=57.8, Expect=2e-09]} {RNA1509_14615} {RNA1310_14786, RNA1509_14615} {RNA1509_14615, RNA815_10750} |
10. | MligTC455_51746 | 193 | 4.03 | Mlig455_008059 | Neo: - Age: - |
FOXJ3 | 0.96 | - | - | - | - | - | 0.960 | Mlig455_008059 {REF} {Length: 3159} {Pfam: Forkhead domain [PF00250.20, score=125.9]} {Human: ENSG00000198815, FOXJ3, forkhead box J3, [RH, Score=165, Expect=3e-46]} {Mouse: ENSMUSG00000032998, Foxj3, forkhead box J3, [RH, Score=164, Expect=3e-44]} {Dmel: FBgn0004567, slp2, sloppy paired 2, [Score=118, Expect=8e-29]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [Score=115, Expect=3e-29]} {Smed: dd_Smed_v6_12170_0_1, dd_Smed_v6_12170_0_1, [RH, Score=113, Expect=9e-27]} {RNA1509_19637} {RNA1310_12207, RNA1509_19637} {RNA1509_19637, RNA815_17037} |
11. | MligTC455_50297 | 112 | 2.33 | Mlig455_001278 | Neo: - |
0.959 | - | - | - | - | - | 0.959 | Mlig455_001278 {REF} {Length: 6519} {RNA1509_40739} {RNA1310_7443.1} {RNA815_11554} | |
12. | MligTC455_09647 | 49 | 1.02 | Mlig455_001466 | Neo: - Age: - |
0.954 | - | - | - | - | - | 0.954 | Mlig455_001466 {REF} {Length: 340} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_2201} {RNA815_38675} | |
13. | MligTC455_27251 | 266 | 5.55 | Mlig455_016125 | Neo: - Age: logFC(26M/2M)=-0.334 |
0.953 | - | - | - | - | - | 0.953 | Mlig455_016125 {REF} {Length: 5004} {TRANSSPLICED} {RNA1509_21530, RNA1509_8503} {RNA1310_2892.1, RNA1509_21530, RNA1509_8503} {RNA1509_21530, RNA1509_8503, RNA815_1285} | |
14. | MligTC455_32833 | 193 | 4.02 | Mlig455_011012 | Neo: - Age: logFC(26M/2M)=0.827 |
IFT52 | 0.953 | - | - | - | - | - | 0.953 | Mlig455_011012 {REF} {Length: 4326} {TRANSSPLICED} {Pfam: RNA polymerase III transcription factor (TF)IIIC subunit HTH domain [PF09734.11, score=59.9]; Tau95 Triple barrel domain [PF17682.3, score=49.4]} {Human: ENSG00000101052, IFT52, intraflagellar transport 52, [Score=319, Expect=9e-102]} {Mouse: ENSMUSG00000017858, Ift52, intraflagellar transport 52, [Score=330, Expect=3e-106]} {Dmel: FBgn0031829, IFT52, Intraflagellar transport 52, [Score=171, Expect=6e-47]} {Celegans: WBGene00003886, osm-6, Osm-6 protein, [Score=218, Expect=1e-63]} {Smed: dd_Smed_v6_5043_0_1, dd_Smed_v6_5043_0_1, [Score=350, Expect=2e-114]} {RNA1509_8537} {RNA1310_16849} {RNA815_7203} |
15. | MligTC455_54156 | 465 | 9.68 | Mlig455_035955 | Neo: - Age: logFC(26M/2M)=-0.401 |
PPP1R36 | 0.952 | - | - | - | 0.952 | - | - | Mlig455_035955 {REF} {Length: 2382} {Pfam: Protein phosphatase 1 inhibitor [PF14895.8, score=139.0]} {Human: ENSG00000165807, PPP1R36, protein phosphatase 1 regulatory subunit 36, [RH, Score=191, Expect=1e-55]} {Mouse: ENSMUSG00000052221, Ppp1r36, protein phosphatase 1, regulatory subunit 36, [RH, Score=167, Expect=5e-47]} {RNA1509_6292} {RNA1310_2911.1, RNA1509_6292} {RNA1509_6292, RNA815_5971.1} |
16. | MligTC455_24553 | 855 | 17.8 | Mlig455_023662 | Neo: - Age: logFC(26M/2M)=-1.366 |
IQCE | 0.951 | - | - | - | 0.951 | - | - | Mlig455_023662 {REF} {Length: 4080} {TRANSSPLICED} {Human: ENSG00000106012, IQCE, IQ motif containing E, [Score=102, Expect=4e-23]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [Score=102, Expect=5e-23]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [Score=65.1, Expect=1e-11]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1} |
17. | MligTC455_47690 | 277 | 5.77 | Mlig455_001541 | Neo: - Age: - |
UBTD2 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_001541 {REF} {Length: 3532} {Pfam: Ubiquitin-binding domain [PF16455.7, score=120.2]; Ubiquitin family [PF00240.25, score=33.4]} {Human: ENSG00000168246, UBTD2, ubiquitin domain containing 2, [RH, Score=216, Expect=7e-70]} {Mouse: ENSMUSG00000044949, Ubtd2, ubiquitin domain containing 2, [RH, Score=217, Expect=2e-70]} {Dmel: FBgn0264712, CG1172, [RH, Score=194, Expect=3e-61]} {Smed: dd_Smed_v6_3009_0_1, dd_Smed_v6_3009_0_1, [RH, Score=199, Expect=3e-63]} {RNA1509_42408} {RNA1310_33971, RNA1509_42408} {RNA1509_42408, RNA815_29256} |
18. | MligTC455_24552 | 1774 | 36.95 | Mlig455_015821, Mlig455_015828 | Neo: - Age: Up-Up-Up |
IQCE | 0.95 | - | - | - | 0.950 | - | - | Mlig455_015821 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1} Mlig455_015828 {REF} {Length: 2744} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1, RNA1509_3714} {RNA1509_3714, RNA815_2091.1} |
19. | MligTC455_25471 | 545 | 11.35 | Mlig455_021774 | Neo: - Age: Up-Down-Down |
0.95 | - | - | - | - | - | 0.950 | Mlig455_021774 {REF} {Length: 4546} {TRANSSPLICED} {Pfam: Glypican [PF01153.21, score=18.1]} {RNA1509_21568, RNA1509_33358, RNA1509_36305} {RNA1310_4091.1, RNA1509_21568, RNA1509_33358, RNA1509_36305} {RNA1509_21568, RNA1509_33358, RNA1509_36305, RNA815_163.1} |