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Results for MligTC455_44084

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_44084 235 4.90 Mlig455_011457

Neo: -

Age: -

FLCN Mlig455_011457 {REF} {Length: 5279} {TRANSSPLICED} {Pfam: Vesicle coat protein involved in Golgi to plasma membrane transport [PF11704.10, score=126.0]; Forkhead domain [PF00250.20, score=110.5]; Folliculin C-terminal domain [PF16692.7, score=107.0]} {Human: ENSG00000154803, FLCN, folliculin, [Score=209, Expect=1e-56]} {Mouse: ENSMUSG00000032633, Flcn, folliculin, [Score=208, Expect=1e-56]} {Dmel: FBgn0029504, CHES-1-like, Checkpoint suppressor 1-like, [RH, Score=139, Expect=1e-32]} {Celegans: WBGene00017699, flcn-1, F22D3.2 protein; FoLliCuliN, [RH, Score=97.1, Expect=3e-20]} {Smed: dd_Smed_v6_4329_0_2, dd_Smed_v6_4329_0_2, [Score=148, Expect=3e-37]} {RNA1509_11130, RNA1509_33195} {RNA1310_5404, RNA1509_33195} {RNA1509_33195, RNA815_1916}

Cumulative graph for MligTC455_44084

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.069 2.846 0.96728 1.00000
RegionR2 -0.144 2.846 0.85669 1.00000
RegionR3 0.162 2.846 0.79366 1.00000
RegionR4 -0.15 2.846 0.84130 1.00000
RegionR5 0.797 2.846 0.14857 0.40045
RegionR6 0.443 2.846 0.50198 1.00000
RegionR7 0.357 2.846 0.65790 1.00000
RegionR8 -1.533 2.846 0.23326 0.84755

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -5.468 2.846 0.31122 1.00000
RegenerationR2 1.809 2.846 0.00411 0.09885
RegenerationR3 0.985 2.846 0.15326 0.58302
RegenerationR4 0.907 2.846 0.21707 0.66419
RegenerationR5 0.769 2.846 0.21042 0.64416
RegenerationR6 -0.135 2.846 0.85381 1.00000
RegenerationBL -0.037 2.846 0.97291 1.00000
RegenerationTP 0.011 2.846 0.98935 1.00000


Genes with expression patterns similar to MligTC455_44084

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_44084 235 4.9 Mlig455_011457

Neo: -

Age: -

FLCN 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_011457 {REF} {Length: 5279} {TRANSSPLICED} {Pfam: Vesicle coat protein involved in Golgi to plasma membrane transport [PF11704.10, score=126.0]; Forkhead domain [PF00250.20, score=110.5]; Folliculin C-terminal domain [PF16692.7, score=107.0]} {Human: ENSG00000154803, FLCN, folliculin, [Score=209, Expect=1e-56]} {Mouse: ENSMUSG00000032633, Flcn, folliculin, [Score=208, Expect=1e-56]} {Dmel: FBgn0029504, CHES-1-like, Checkpoint suppressor 1-like, [RH, Score=139, Expect=1e-32]} {Celegans: WBGene00017699, flcn-1, F22D3.2 protein; FoLliCuliN, [RH, Score=97.1, Expect=3e-20]} {Smed: dd_Smed_v6_4329_0_2, dd_Smed_v6_4329_0_2, [Score=148, Expect=3e-37]} {RNA1509_11130, RNA1509_33195} {RNA1310_5404, RNA1509_33195} {RNA1509_33195, RNA815_1916}
2. MligTC455_50154 1013 21.11 Mlig455_062175, Mlig455_062207

Neo: -

Age: -

Region-enriched R5: 1.772/0.00870

Regeneration-upregulated BL: 1.960

Regeneration-enriched BL: 1.960

POU6F2 1.793 - - - 0.960 - 0.833

Mlig455_062175 {REF} {Length: 3567} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=89.0]; Homeodomain [PF00046.31, score=61.4]} {Human: ENSG00000106536, POU6F2, POU class 6 homeobox 2, [Score=161, Expect=5e-42]} {Mouse: ENSMUSG00000009734, Pou6f2, POU domain, class 6, transcription factor 2, [Score=161, Expect=1e-42]} {Dmel: FBgn0261588, pdm3, pou domain motif 3, [Score=126, Expect=2e-30]} {Celegans: WBGene00000441, ceh-18, Homeobox protein ceh-18, [Score=109, Expect=3e-25]} {Smed: dd_Smed_v6_13010_0_1, dd_Smed_v6_13010_0_1, [Score=130, Expect=2e-32]} {RNA1509_33080, RNA1509_36081} {RNA1310_10551.1, RNA1509_33080, RNA1509_36081} {RNA1509_33080, RNA1509_36081, RNA815_8676}

Mlig455_062207 {REF} {Length: 3563} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=89.0]; Homeodomain [PF00046.31, score=59.8]; Helix-turn-helix domain [PF13560.8, score=19.1]} {Human: ENSG00000106536, POU6F2, POU class 6 homeobox 2, [Score=159, Expect=1e-41]} {Mouse: ENSMUSG00000009734, Pou6f2, POU domain, class 6, transcription factor 2, [Score=159, Expect=7e-42]} {Dmel: FBgn0261588, pdm3, pou domain motif 3, [Score=125, Expect=7e-30]} {Celegans: WBGene00000441, ceh-18, Homeobox protein ceh-18, [Score=107, Expect=1e-24]} {Smed: dd_Smed_v6_13010_0_1, dd_Smed_v6_13010_0_1, [Score=130, Expect=2e-32]} {RNA1509_33080} {RNA1310_10551.1} {RNA815_8676}
3. MligTC455_05039 320 6.67 Mlig455_035597

Neo: -

Age: Up-Down-Up

KCND1 1.779 - - - 0.828 - 0.951 Mlig455_035597 {REF} {Length: 3227} {TRANSSPLICED} {Pfam: Ion transport protein [PF00520.33, score=85.6]; Ion channel [PF07885.18, score=50.8]; Domain of unknown function (DUF3399) [PF11879.10, score=38.6]} {Human: ENSG00000102057, KCND1, potassium voltage-gated channel subfamily D member 1, [Score=261, Expect=3e-81]; ENSG00000184408, KCND2, potassium voltage-gated channel subfamily D member 2, [Score=258, Expect=2e-80]; ENSG00000171385, KCND3, potassium voltage-gated channel subfamily D member 3, [Score=249, Expect=1e-76]} {Mouse: ENSMUSG00000009731, Kcnd1, potassium voltage-gated channel, Shal-related family, member 1, [Score=261, Expect=3e-81]; ENSMUSG00000060882, Kcnd2, potassium voltage-gated channel, Shal-related family, member 2, [Score=258, Expect=4e-80]; ENSMUSG00000040896, Kcnd3, potassium voltage-gated channel, Shal-related family, member 3, [Score=249, Expect=7e-77]} {Dmel: FBgn0005564, Shal, Shaker cognate l, [Score=275, Expect=1e-87]} {Celegans: WBGene00022240, shl-1, SHaL family of potassium channels, [Score=270, Expect=2e-85]} {Smed: dd_Smed_v6_15876_0_1, dd_Smed_v6_15876_0_1, [Score=245, Expect=3e-75]} {RNA1509_13132} {RNA1310_4146.2} {RNA815_997}
4. MligTC455_52201 712 14.84 Mlig455_000379

Neo: Irradiation

Age: Up-Down-Down

Region-specific R4: 3.455

Region-enriched R4: 2.637/0.00000
Region-enriched R2: 1.808/0.04958

Regeneration-downregulated R4: -1.839

Regeneration-depleted R4: -1.839

CHEK2 1.772 - - - 0.807 - 0.965 Mlig455_000379 {REF} {Length: 2826} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=205.8]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=111.0]; FHA domain [PF00498.28, score=45.6]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=25.5]; Kinase-like [PF14531.8, score=19.4]; ABC1 atypical kinase-like domain [PF03109.18, score=19.2]} {Human: ENSG00000183765, CHEK2, checkpoint kinase 2, [Score=231, Expect=1e-67]} {Mouse: ENSMUSG00000029521, Chek2, checkpoint kinase 2, [Score=226, Expect=7e-66]} {Dmel: FBgn0019686, lok, loki, [Score=219, Expect=3e-64]} {Celegans: WBGene00000499, chk-2, Serine/threonine-protein kinase chk-2, [Score=174, Expect=1e-47]} {Smed: dd_Smed_v6_6620_0_1, dd_Smed_v6_6620_0_1, [Score=234, Expect=2e-70]} {RNA1509_3579} {RNA1310_6215, RNA1509_3579} {RNA1509_3579, RNA815_2071.1}
5. MligTC455_35453 76 1.58 Mlig455_034810, Mlig455_047899, Mlig455_047985

Neo: Germline

Age: -

Region-enriched R5: 2.528/0.04280

0.971 - - - - 0.971 -

Mlig455_034810 {REF} {Length: 182} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_121697}

Mlig455_047899 {REF} {Length: 1196} {RNA1509_55040} {RNA1310_81175} {RNA815_38567}

Mlig455_047985 {REF} {Length: 454} {NoTransDecoderORF} {RNA1509_45210} {RNA1310_28413.1} {RNA815_41251}
6. MligTC455_47784 987 20.56 Mlig455_042427, Mlig455_042482

Neo: Irradiation

Age: Down-Up-Down

LPIN3 0.968 - - - - - 0.968

Mlig455_042427 {REF} {Length: 3949} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=315.0]; lipin, N-terminal conserved region [PF04571.16, score=124.4]; Lipin/Ned1/Smp2 multi-domain protein middle domain [PF16876.7, score=88.2]} {Human: ENSG00000132793, LPIN3, lipin 3, [RH, Score=447, Expect=2e-144]} {Mouse: ENSMUSG00000027412, Lpin3, lipin 3, [RH, Score=441, Expect=3e-142]; ENSMUSG00000020593, Lpin1, lipin 1, [RH, Score=427, Expect=2e-136]} {Dmel: FBgn0263593, Lpin, Lipin, [RH, Score=355, Expect=2e-108]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [RH, Score=255, Expect=2e-73]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [RH, Score=407, Expect=1e-130]} {RNA1509_2460} {RNA1310_4371} {RNA815_2379.1}

Mlig455_042482 {REF} {Length: 3845} {Pfam: LNS2 (Lipin/Ned1/Smp2) [PF08235.15, score=315.1]; Lipin/Ned1/Smp2 multi-domain protein middle domain [PF16876.7, score=88.3]; lipin, N-terminal conserved region [PF04571.16, score=87.5]} {Human: ENSG00000132793, LPIN3, lipin 3, [RH, Score=414, Expect=5e-132]} {Mouse: ENSMUSG00000027412, Lpin3, lipin 3, [RH, Score=401, Expect=2e-127]} {Dmel: FBgn0263593, Lpin, Lipin, [RH, Score=355, Expect=6e-109]} {Celegans: WBGene00010425, lpin-1, LiPIN (Mammalian lipodystrophy associated) homolog, [RH, Score=255, Expect=1e-73]} {Smed: dd_Smed_v6_8002_0_1, dd_Smed_v6_8002_0_1, [RH, Score=407, Expect=2e-131]} {RNA1509_2460, RNA1509_26861, RNA1509_31871, RNA1509_42018} {RNA1310_4371, RNA1509_26861, RNA1509_31871, RNA1509_42018} {RNA1509_26861, RNA1509_31871, RNA1509_42018, RNA815_2379.1}
7. MligTC455_52372 288 5.99 Mlig455_012761

Neo: -

Age: logFC(26M/2M)=-0.342

CEP89 0.965 - - - 0.965 - - Mlig455_012761 {REF} {Length: 3139} {Pfam: Uncharacterised protein family (UPF0242) N-terminus [PF06785.13, score=23.6]} {Human: ENSG00000121289, CEP89, centrosomal protein 89, [RH, Score=113, Expect=1e-25]} {Mouse: ENSMUSG00000023072, Cep89, centrosomal protein 89, [RH, Score=106, Expect=2e-23]} {Smed: dd_Smed_v6_13073_0_1, dd_Smed_v6_13073_0_1, [RH, Score=80.5, Expect=1e-15]} {RNA1509_10380} {RNA1310_5262.1} {RNA815_3458.1}
8. MligTC455_35872 276 5.76 Mlig455_039093

Neo: -

Age: Up-Up-Down

0.964 - - - - - 0.964 Mlig455_039093 {REF} {Length: 2636} {Pfam: Homeodomain-like domain [PF13384.8, score=26.2]; Helix-turn-helix domain [PF13518.8, score=25.9]} {RNA1509_48694} {RNA1310_48256} {RNA815_5960}
9. MligTC455_41881 799 16.64 Mlig455_011980, Mlig455_068626

Neo: -

Age: -

FGFR1OP 0.96 - - - - - 0.960

Mlig455_011980 {REF} {Length: 2999} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=38.9]; LisH [PF16045.7, score=17.6]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=101, Expect=4e-23]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=99.4, Expect=2e-22]} {Smed: dd_Smed_v6_5371_0_1, dd_Smed_v6_5371_0_1, [Score=58.2, Expect=3e-09]} {RNA1509_14615} {RNA1310_13253.1} {RNA815_34617.1}

Mlig455_068626 {REF} {Length: 2876} {Pfam: FOP N terminal dimerisation domain [PF09398.12, score=39.1]; LisH [PF16045.7, score=17.8]} {Human: ENSG00000213066, FGFR1OP, FGFR1 oncogene partner, [RH, Score=104, Expect=3e-24]} {Mouse: ENSMUSG00000069135, Fgfr1op, Fgfr1 oncogene partner, [RH, Score=99.4, Expect=1e-22]} {Smed: dd_Smed_v6_5371_0_2, dd_Smed_v6_5371_0_2, [Score=57.8, Expect=2e-09]} {RNA1509_14615} {RNA1310_14786, RNA1509_14615} {RNA1509_14615, RNA815_10750}
10. MligTC455_51746 193 4.03 Mlig455_008059

Neo: -

Age: -

FOXJ3 0.96 - - - - - 0.960 Mlig455_008059 {REF} {Length: 3159} {Pfam: Forkhead domain [PF00250.20, score=125.9]} {Human: ENSG00000198815, FOXJ3, forkhead box J3, [RH, Score=165, Expect=3e-46]} {Mouse: ENSMUSG00000032998, Foxj3, forkhead box J3, [RH, Score=164, Expect=3e-44]} {Dmel: FBgn0004567, slp2, sloppy paired 2, [Score=118, Expect=8e-29]} {Celegans: WBGene00001434, fkh-2, ForKHead transcription factor family, [Score=115, Expect=3e-29]} {Smed: dd_Smed_v6_12170_0_1, dd_Smed_v6_12170_0_1, [RH, Score=113, Expect=9e-27]} {RNA1509_19637} {RNA1310_12207, RNA1509_19637} {RNA1509_19637, RNA815_17037}
11. MligTC455_50297 112 2.33 Mlig455_001278

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.874

0.959 - - - - - 0.959 Mlig455_001278 {REF} {Length: 6519} {RNA1509_40739} {RNA1310_7443.1} {RNA815_11554}
12. MligTC455_09647 49 1.02 Mlig455_001466

Neo: -

Age: -

0.954 - - - - - 0.954 Mlig455_001466 {REF} {Length: 340} {TRANSSPLICED} {NoTransDecoderORF} {RNA1310_2201} {RNA815_38675}
13. MligTC455_27251 266 5.55 Mlig455_016125

Neo: -

Age: logFC(26M/2M)=-0.334

0.953 - - - - - 0.953 Mlig455_016125 {REF} {Length: 5004} {TRANSSPLICED} {RNA1509_21530, RNA1509_8503} {RNA1310_2892.1, RNA1509_21530, RNA1509_8503} {RNA1509_21530, RNA1509_8503, RNA815_1285}
14. MligTC455_32833 193 4.02 Mlig455_011012

Neo: -

Age: logFC(26M/2M)=0.827

IFT52 0.953 - - - - - 0.953 Mlig455_011012 {REF} {Length: 4326} {TRANSSPLICED} {Pfam: RNA polymerase III transcription factor (TF)IIIC subunit HTH domain [PF09734.11, score=59.9]; Tau95 Triple barrel domain [PF17682.3, score=49.4]} {Human: ENSG00000101052, IFT52, intraflagellar transport 52, [Score=319, Expect=9e-102]} {Mouse: ENSMUSG00000017858, Ift52, intraflagellar transport 52, [Score=330, Expect=3e-106]} {Dmel: FBgn0031829, IFT52, Intraflagellar transport 52, [Score=171, Expect=6e-47]} {Celegans: WBGene00003886, osm-6, Osm-6 protein, [Score=218, Expect=1e-63]} {Smed: dd_Smed_v6_5043_0_1, dd_Smed_v6_5043_0_1, [Score=350, Expect=2e-114]} {RNA1509_8537} {RNA1310_16849} {RNA815_7203}
15. MligTC455_54156 465 9.68 Mlig455_035955

Neo: -

Age: logFC(26M/2M)=-0.401

PPP1R36 0.952 - - - 0.952 - - Mlig455_035955 {REF} {Length: 2382} {Pfam: Protein phosphatase 1 inhibitor [PF14895.8, score=139.0]} {Human: ENSG00000165807, PPP1R36, protein phosphatase 1 regulatory subunit 36, [RH, Score=191, Expect=1e-55]} {Mouse: ENSMUSG00000052221, Ppp1r36, protein phosphatase 1, regulatory subunit 36, [RH, Score=167, Expect=5e-47]} {RNA1509_6292} {RNA1310_2911.1, RNA1509_6292} {RNA1509_6292, RNA815_5971.1}
16. MligTC455_24553 855 17.8 Mlig455_023662

Neo: -

Age: logFC(26M/2M)=-1.366

IQCE 0.951 - - - 0.951 - - Mlig455_023662 {REF} {Length: 4080} {TRANSSPLICED} {Human: ENSG00000106012, IQCE, IQ motif containing E, [Score=102, Expect=4e-23]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [Score=102, Expect=5e-23]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [Score=65.1, Expect=1e-11]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}
17. MligTC455_47690 277 5.77 Mlig455_001541

Neo: -

Age: -

UBTD2 0.951 - - - - - 0.951 Mlig455_001541 {REF} {Length: 3532} {Pfam: Ubiquitin-binding domain [PF16455.7, score=120.2]; Ubiquitin family [PF00240.25, score=33.4]} {Human: ENSG00000168246, UBTD2, ubiquitin domain containing 2, [RH, Score=216, Expect=7e-70]} {Mouse: ENSMUSG00000044949, Ubtd2, ubiquitin domain containing 2, [RH, Score=217, Expect=2e-70]} {Dmel: FBgn0264712, CG1172, [RH, Score=194, Expect=3e-61]} {Smed: dd_Smed_v6_3009_0_1, dd_Smed_v6_3009_0_1, [RH, Score=199, Expect=3e-63]} {RNA1509_42408} {RNA1310_33971, RNA1509_42408} {RNA1509_42408, RNA815_29256}
18. MligTC455_24552 1774 36.95 Mlig455_015821, Mlig455_015828

Neo: -

Age: Up-Up-Up

IQCE 0.95 - - - 0.950 - -

Mlig455_015821 {REF} {Length: 2698} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1} {RNA815_2091.1}

Mlig455_015828 {REF} {Length: 2744} {TRANSSPLICED} {Pfam: Fez1 [PF06818.17, score=21.8]; IQ calmodulin-binding motif [PF00612.29, score=21.0]} {Human: ENSG00000106012, IQCE, IQ motif containing E, [RH, Score=127, Expect=5e-30]} {Mouse: ENSMUSG00000036555, Iqce, IQ motif containing E, [RH, Score=128, Expect=1e-30]} {Smed: dd_Smed_v6_7345_0_1, dd_Smed_v6_7345_0_1, [RH, Score=73.6, Expect=7e-14]} {RNA1509_3714} {RNA1310_6916.1, RNA1509_3714} {RNA1509_3714, RNA815_2091.1}
19. MligTC455_25471 545 11.35 Mlig455_021774

Neo: -

Age: Up-Down-Down

0.95 - - - - - 0.950 Mlig455_021774 {REF} {Length: 4546} {TRANSSPLICED} {Pfam: Glypican [PF01153.21, score=18.1]} {RNA1509_21568, RNA1509_33358, RNA1509_36305} {RNA1310_4091.1, RNA1509_21568, RNA1509_33358, RNA1509_36305} {RNA1509_21568, RNA1509_33358, RNA1509_36305, RNA815_163.1}

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