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Results for MligTC455_45486

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_45486 487 10.14 Mlig455_019746

Neo: -

Age: Down-Up-Up

DLG2 Mlig455_019746 {REF} {Length: 3340} {Pfam: Guanylate kinase [PF00625.23, score=164.7]; PDZ domain [PF00595.26, score=69.8]; PDZ domain [PF17820.3, score=37.7]; SH3 domain [PF00018.30, score=33.0]; Variant SH3 domain [PF07653.19, score=27.2]; PDZ domain [PF13180.8, score=22.1]; Variant SH3 domain [PF14604.8, score=20.5]; Procyclic acidic repetitive protein (PARP) [PF05887.13, score=19.1]} {Human: ENSG00000150672, DLG2, discs large MAGUK scaffold protein 2, [RH, Score=427, Expect=6e-141]} {Mouse: ENSMUSG00000052572, Dlg2, discs large MAGUK scaffold protein 2, [RH, Score=426, Expect=1e-140]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=434, Expect=1e-141]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [RH, Score=343, Expect=9e-107]} {Smed: dd_Smed_v6_8511_0_1, dd_Smed_v6_8511_0_1, [RH, Score=317, Expect=2e-101]} {RNA1509_16120, RNA1509_26114} {RNA1310_2555.1, RNA1509_16120} {RNA1509_16120, RNA815_2319}

Cumulative graph for MligTC455_45486

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -6.968 3.748 0.04437 0.50707
RegionR2 0.687 3.748 0.47700 0.86190
RegionR3 0.895 3.748 0.28187 0.82541
RegionR4 0.65 3.748 0.48792 0.81515
RegionR5 1.565 3.748 0.01565 0.08074
RegionR6 1.237 3.748 0.10822 0.60138
RegionR7 0.772 3.748 0.42941 1.00000
RegionR8 1.164 3.748 0.25192 0.87153

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.33 3.748 0.99997 1.00000
RegenerationR2 0.561 3.748 0.24829 0.69499
RegenerationR3 -0.038 3.748 0.94288 1.00000
RegenerationR4 0.213 3.748 0.70486 0.95542
RegenerationR5 -0.194 3.748 0.69515 0.94979
RegenerationR6 0.145 3.748 0.78967 0.97230
RegenerationBL 0.422 3.748 0.45651 0.82413
RegenerationTP -1.265 3.748 0.09993 0.49185


Genes with expression patterns similar to MligTC455_45486

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_45486 487 10.14 Mlig455_019746

Neo: -

Age: Down-Up-Up

DLG2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_019746 {REF} {Length: 3340} {Pfam: Guanylate kinase [PF00625.23, score=164.7]; PDZ domain [PF00595.26, score=69.8]; PDZ domain [PF17820.3, score=37.7]; SH3 domain [PF00018.30, score=33.0]; Variant SH3 domain [PF07653.19, score=27.2]; PDZ domain [PF13180.8, score=22.1]; Variant SH3 domain [PF14604.8, score=20.5]; Procyclic acidic repetitive protein (PARP) [PF05887.13, score=19.1]} {Human: ENSG00000150672, DLG2, discs large MAGUK scaffold protein 2, [RH, Score=427, Expect=6e-141]} {Mouse: ENSMUSG00000052572, Dlg2, discs large MAGUK scaffold protein 2, [RH, Score=426, Expect=1e-140]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=434, Expect=1e-141]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [RH, Score=343, Expect=9e-107]} {Smed: dd_Smed_v6_8511_0_1, dd_Smed_v6_8511_0_1, [RH, Score=317, Expect=2e-101]} {RNA1509_16120, RNA1509_26114} {RNA1310_2555.1, RNA1509_16120} {RNA1509_16120, RNA815_2319}
2. MligTC455_25480 454 9.45 Mlig455_002934

Neo: -

Age: -

ITK 2.545 0.954 - 0.795 - 0.796 - Mlig455_002934 {REF} {Length: 6820} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=267.9]; Protein kinase domain [PF00069.27, score=133.8]; SH2 domain [PF00017.26, score=77.3]; PH domain [PF00169.31, score=32.0]; Variant SH3 domain [PF14604.8, score=28.5]; SH3 domain [PF00018.30, score=27.5]; BTK motif [PF00779.21, score=24.1]; SH3 domain [PF17902.3, score=18.6]} {Human: ENSG00000113263, ITK, IL2 inducible T cell kinase, [Score=432, Expect=5e-143]; ENSG00000010671, BTK, Bruton tyrosine kinase, [Score=427, Expect=2e-140]; ENSG00000135605, TEC, tec protein tyrosine kinase, [Score=416, Expect=2e-136]} {Mouse: ENSMUSG00000020395, Itk, IL2 inducible T cell kinase, [RH, Score=420, Expect=3e-138]} {Dmel: FBgn0003502, Btk29A, Btk family kinase at 29A, [RH, Score=451, Expect=2e-148]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=294, Expect=7e-92]} {Smed: dd_Smed_v6_4818_0_1, dd_Smed_v6_4818_0_1, [RH, Score=641, Expect=0.0]} {RNA1509_14892} {RNA1310_2046, RNA1509_14892} {RNA1509_14892, RNA815_350}
3. MligTC455_37189 502 10.46 Mlig455_000597

Neo: -

Age: logFC(26M/2M)=-0.210

SLC6A5 2.509 0.956 - - 0.795 - 0.758 Mlig455_000597 {REF} {Length: 3309} {Pfam: Sodium:neurotransmitter symporter family [PF00209.20, score=618.6]} {Human: ENSG00000165970, SLC6A5, solute carrier family 6 member 5, [Score=534, Expect=1e-178]} {Mouse: ENSMUSG00000039728, Slc6a5, solute carrier family 6 (neurotransmitter transporter, glycine), member 5, [Score=536, Expect=8e-180]} {Dmel: FBgn0034911, CG5549, [RH, Score=535, Expect=1e-174]} {Celegans: WBGene00004910, snf-11, Transporter, [Score=420, Expect=2e-137]} {Smed: dd_Smed_v6_10458_0_1, dd_Smed_v6_10458_0_1, [RH, Score=717, Expect=0.0]} {RNA1509_9225} {RNA1310_7320} {RNA815_2265}
4. MligTC455_25479 507 10.56 Mlig455_002918

Neo: -

Age: -

ITK 2.476 0.968 - 0.775 - 0.733 - Mlig455_002918 {REF} {Length: 4643} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=267.9]; Protein kinase domain [PF00069.27, score=133.8]; SH2 domain [PF00017.26, score=77.3]; PH domain [PF00169.31, score=32.0]; BTK motif [PF00779.21, score=29.7]; Variant SH3 domain [PF14604.8, score=28.5]; SH3 domain [PF00018.30, score=27.5]; SH3 domain [PF17902.3, score=18.6]} {Human: ENSG00000113263, ITK, IL2 inducible T cell kinase, [RH, Score=434, Expect=9e-144]} {Mouse: ENSMUSG00000031264, Btk, Bruton agammaglobulinemia tyrosine kinase, [RH, Score=430, Expect=7e-142]; ENSMUSG00000020395, Itk, IL2 inducible T cell kinase, [RH, Score=421, Expect=7e-139]} {Dmel: FBgn0003502, Btk29A, Btk family kinase at 29A, [RH, Score=452, Expect=6e-149]} {Celegans: WBGene00005077, src-1, Tyrosine protein-kinase src-1, [Score=294, Expect=7e-92]} {Smed: dd_Smed_v6_4818_0_1, dd_Smed_v6_4818_0_1, [RH, Score=643, Expect=0.0]} {RNA1509_14892} {RNA1310_2046} {RNA815_1375.1}
5. MligTC455_47509 816 17 Mlig455_070906

Neo: -

Age: -

GALK2 1.798 0.965 - - 0.833 - - Mlig455_070906 {REF} {Length: 3183} {TRANSSPLICED} {Pfam: Galactokinase galactose-binding signature [PF10509.11, score=81.8]; GHMP kinases C terminal [PF08544.15, score=56.5]; GHMP kinases N terminal domain [PF00288.28, score=49.1]} {Human: ENSG00000156958, GALK2, galactokinase 2, [RH, Score=310, Expect=3e-100]} {Mouse: ENSMUSG00000027207, Galk2, galactokinase 2, [RH, Score=320, Expect=2e-104]} {Dmel: FBgn0263199, Galk, Galactokinase, [RH, Score=255, Expect=5e-79]} {Celegans: WBGene00006461, tag-96, [RH, Score=207, Expect=1e-61]} {Smed: dd_Smed_v6_3084_0_1, dd_Smed_v6_3084_0_1, [RH, Score=308, Expect=8e-100]} {RNA1509_24036, RNA1509_32107, RNA1509_38803, RNA1509_39186, RNA1509_53249, RNA1509_56440} {RNA1310_10159.2, RNA1509_24036, RNA1509_32107, RNA1509_38803, RNA1509_39186, RNA1509_53249, RNA1509_56440} {RNA1509_24036, RNA1509_32107, RNA1509_38803, RNA1509_39186, RNA1509_53249, RNA1509_56440, RNA815_7636}
6. MligTC455_44916 688 14.33 Mlig455_025259

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.436

GMPPA 1.777 0.951 - - - 0.826 - Mlig455_025259 {REF} {Length: 1859} {TRANSSPLICED} {Pfam: Nucleotidyl transferase [PF00483.25, score=97.0]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=29.6]; MobA-like NTP transferase domain [PF12804.9, score=21.3]} {Human: ENSG00000144591, GMPPA, GDP-mannose pyrophosphorylase A, [RH, Score=458, Expect=1e-159]} {Mouse: ENSMUSG00000033021, Gmppa, GDP-mannose pyrophosphorylase A, [RH, Score=461, Expect=4e-161]} {Dmel: FBgn0034035, CG8207, [RH, Score=450, Expect=1e-156]} {Celegans: WBGene00021628, Y47D9A.1, [RH, Score=398, Expect=9e-137]} {Smed: dd_Smed_v6_4150_0_1, dd_Smed_v6_4150_0_1, [RH, Score=496, Expect=6e-175]} {RNA1509_37379} {RNA1310_15544, RNA1509_37379} {RNA1509_37379, RNA815_10312.2}
7. MligTC455_40220 745 15.51 Mlig455_015916, Mlig455_059676

Neo: -

Age: -

SH3D19 1.772 0.952 - - - 0.820 -

Mlig455_015916 {REF} {Length: 3055} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=148.5]; Variant SH3 domain [PF14604.8, score=121.2]; Variant SH3 domain [PF07653.19, score=98.2]} {Human: ENSG00000109686, SH3D19, SH3 domain containing 19, [RH, Score=110, Expect=1e-24]} {Mouse: ENSMUSG00000028082, Sh3d19, SH3 domain protein D19, [RH, Score=111, Expect=3e-25]} {Dmel: FBgn0023388, Dap160, Dynamin associated protein 160, [Score=62.4, Expect=9e-10]} {Celegans: WBGene00006405, itsn-1, ITSN (Intersectin) family, [RH, Score=67.0, Expect=2e-11]} {Smed: dd_Smed_v6_3992_0_1, dd_Smed_v6_3992_0_1, [Score=62.0, Expect=8e-10]} {RNA1509_6888} {RNA1310_6388} {RNA815_21405}

Mlig455_059676 {REF} {Length: 3156} {TRANSSPLICED} {Pfam: SH3 domain [PF00018.30, score=144.8]; Variant SH3 domain [PF14604.8, score=122.3]; Variant SH3 domain [PF07653.19, score=92.6]} {Human: ENSG00000109686, SH3D19, SH3 domain containing 19, [RH, Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000028082, Sh3d19, SH3 domain protein D19, [RH, Score=110, Expect=8e-25]} {Dmel: FBgn0023388, Dap160, Dynamin associated protein 160, [Score=67.8, Expect=2e-11]} {Celegans: WBGene00006405, itsn-1, ITSN (Intersectin) family, [RH, Score=66.6, Expect=3e-11]} {Smed: dd_Smed_v6_3992_0_1, dd_Smed_v6_3992_0_1, [Score=56.2, Expect=4e-08]} {RNA1509_6888} {RNA1310_6388, RNA1509_6888} {RNA1509_6888, RNA815_21405}
8. MligTC455_47529 654 13.62 Mlig455_016302

Neo: -

Age: -

MED19 1.758 0.960 0.798 - - - - Mlig455_016302 {REF} {Length: 1225} {TRANSSPLICED} {Pfam: Mediator of RNA pol II transcription subunit 19 [PF10278.11, score=122.9]} {Human: ENSG00000156603, MED19, mediator complex subunit 19, [RH, Score=117, Expect=1e-30]} {Mouse: ENSMUSG00000027080, Med19, mediator complex subunit 19, [RH, Score=117, Expect=8e-31]} {Dmel: FBgn0036761, MED19, Mediator complex subunit 19, [RH, Score=82.8, Expect=1e-17]} {Celegans: WBGene00007019, mdt-19, Mediator of RNA polymerase II transcription subunit 19, [RH, Score=60.8, Expect=7e-11]} {Smed: dd_Smed_v6_4283_0_1, dd_Smed_v6_4283_0_1, [RH, Score=90.1, Expect=1e-20]} {RNA1509_20056, RNA1509_53904} {RNA1310_27356.1, RNA1509_20056, RNA1509_53904} {RNA1509_20056, RNA1509_53904, RNA815_18046.1}
9. MligTC455_47508 798 16.63 Mlig455_009512

Neo: -

Age: -

Region-enriched R5: 1.090/0.00556

GALK2 1.736 0.976 - - 0.760 - - Mlig455_009512 {REF} {Length: 2850} {TRANSSPLICED} {Pfam: Galactokinase galactose-binding signature [PF10509.11, score=78.9]; GHMP kinases C terminal [PF08544.15, score=56.8]; GHMP kinases N terminal domain [PF00288.28, score=49.1]} {Human: ENSG00000156958, GALK2, galactokinase 2, [RH, Score=311, Expect=1e-100]} {Mouse: ENSMUSG00000027207, Galk2, galactokinase 2, [RH, Score=321, Expect=6e-105]} {Dmel: FBgn0263199, Galk, Galactokinase, [RH, Score=255, Expect=3e-79]} {Celegans: WBGene00006461, tag-96, [RH, Score=211, Expect=6e-63]} {Smed: dd_Smed_v6_3084_0_1, dd_Smed_v6_3084_0_1, [RH, Score=305, Expect=8e-99]} {RNA1509_53249} {RNA1310_10159.2} {RNA815_7636}
10. MligTC455_23693 1259 26.23 Mlig455_026716, Mlig455_051705

Neo: -

Age: -

Region-enriched R5: 1.803/0.00084

MICALL2 1.714 0.952 - - - - 0.762

Mlig455_026716 {REF} {Length: 3744} {TRANSSPLICED} {Pfam: Bivalent Mical/EHBP Rab binding domain [PF12130.10, score=88.2]} {Human: ENSG00000164877, MICALL2, MICAL like 2, [Score=89.7, Expect=1e-17]} {Mouse: ENSMUSG00000051586, Mical3, microtubule associated monooxygenase, calponin and LIM domain containing 3, [RH, Score=74.7, Expect=4e-13]} {Smed: dd_Smed_v6_4568_0_1, dd_Smed_v6_4568_0_1, [Score=73.6, Expect=3e-13]} {RNA1509_46384} {RNA1310_2796.1} {RNA815_2459}

Mlig455_051705 {REF} {Length: 3718} {TRANSSPLICED} {Pfam: Bivalent Mical/EHBP Rab binding domain [PF12130.10, score=87.8]} {Human: ENSG00000164877, MICALL2, MICAL like 2, [Score=89.7, Expect=1e-17]} {Mouse: ENSMUSG00000051586, Mical3, microtubule associated monooxygenase, calponin and LIM domain containing 3, [RH, Score=75.1, Expect=3e-13]} {Smed: dd_Smed_v6_4568_0_1, dd_Smed_v6_4568_0_1, [Score=74.7, Expect=1e-13]} {RNA1509_46384, RNA1509_5229} {RNA1310_2796.1, RNA1509_5229} {RNA1509_5229, RNA815_2459}
11. MligTC455_25177 330 6.87 Mlig455_058575

Neo: -

Age: Up-Down-Down

1.702 0.952 - - - - 0.750 Mlig455_058575 {REF} {Length: 3172} {RNA1509_34496, RNA1509_56824} {RNA1310_29369, RNA1509_34496} {RNA1509_34496, RNA815_24472}
12. MligTC455_48211 976 20.33 Mlig455_013971, Mlig455_035001

Neo: -

Age: logFC(26M/2M)=0.541

1.684 0.962 - - - 0.722 -

Mlig455_013971 {REF} {Length: 687} {TRANSSPLICED} {Pfam: rRNA biogenesis protein RRP36 [PF06102.14, score=64.0]} {RNA1509_21344} {RNA1310_49166} {RNA815_27804}

Mlig455_035001 {REF} {Length: 688} {TRANSSPLICED} {Pfam: rRNA biogenesis protein RRP36 [PF06102.14, score=64.0]} {RNA1509_21344} {RNA1310_49166, RNA1509_21344} {RNA1509_21344, RNA815_27804}
13. MligTC455_44506 316 6.58 Mlig455_006657

Neo: Int S/G2/M

Age: -

Region-enriched R5: 1.998/0.01447

NUP107 1.667 0.959 - - - 0.708 - Mlig455_006657 {REF} {Length: 3514} {TRANSSPLICED} {Pfam: Nuclear pore protein 84 / 107 [PF04121.15, score=365.9]} {Human: ENSG00000111581, NUP107, nucleoporin 107, [RH, Score=363, Expect=2e-110]} {Mouse: ENSMUSG00000052798, Nup107, nucleoporin 107, [RH, Score=358, Expect=8e-109]} {Dmel: FBgn0027868, Nup107, Nucleoporin 107kD, [RH, Score=266, Expect=4e-76]} {Smed: dd_Smed_v6_5070_0_1, dd_Smed_v6_5070_0_1, [RH, Score=204, Expect=2e-54]} {RNA1509_22557} {RNA1310_4995} {RNA815_1737}
14. MligTC455_49481 2896 60.33 Mlig455_061474

Neo: -

Age: -

Regeneration-upregulated BL: 1.088

Regeneration-enriched BL: 1.088

RBM39 1.667 - - - 0.708 0.959 - Mlig455_061474 {REF} {Length: 2417} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=137.4]; linker between RRM2 and RRM3 domains in RBM39 protein [PF15519.8, score=59.8]} {Human: ENSG00000131051, RBM39, RNA binding motif protein 39, [RH, Score=365, Expect=2e-119]} {Mouse: ENSMUSG00000027620, Rbm39, RNA binding motif protein 39, [RH, Score=365, Expect=1e-119]} {Dmel: FBgn0031883, Caper, [Score=342, Expect=6e-110]} {Celegans: WBGene00021921, Y55F3AM.3, [RH, Score=259, Expect=2e-78]} {Smed: dd_Smed_v6_1932_0_1, dd_Smed_v6_1932_0_1, [RH, Score=273, Expect=2e-85]} {RNA1509_9704} {RNA1310_3436.2, RNA1509_9704} {RNA1509_9704, RNA815_1081.1}
15. MligTC455_45828 282 5.88 Mlig455_038865

Neo: -

Age: -

AARS2 0.972 - - - - 0.972 - Mlig455_038865 {REF} {Length: 3448} {TRANSSPLICED} {Pfam: tRNA synthetases class II (A) [PF01411.21, score=353.7]; Threonyl and Alanyl tRNA synthetase second additional domain [PF07973.16, score=25.5]} {Human: ENSG00000124608, AARS2, alanyl-tRNA synthetase 2, mitochondrial, [Score=421, Expect=2e-130]} {Mouse: ENSMUSG00000023938, Aars2, alanyl-tRNA synthetase 2, mitochondrial, [Score=441, Expect=9e-138]} {Dmel: FBgn0027094, AlaRS, Alanyl-tRNA synthetase, [Score=409, Expect=3e-126]} {Celegans: WBGene00000197, aars-2, Alanine--tRNA ligase, cytoplasmic, [Score=421, Expect=7e-131]} {Smed: dd_Smed_v6_4233_0_1, dd_Smed_v6_4233_0_1, [Score=421, Expect=7e-131]} {RNA1509_11036} {RNA1310_3138.1} {RNA815_933}
16. MligTC455_33846 138 2.87 Mlig455_061676

Neo: -

Age: Up-Up-Down

Region-enriched R2: 2.874/0.04108

DHX58 0.969 - - - - - 0.969 Mlig455_061676 {REF} {Length: 10368} {Pfam: RNA dependent RNA polymerase [PF05183.14, score=177.8]; Type III restriction enzyme, res subunit [PF04851.17, score=46.5]; DEAD/DEAH box helicase [PF00270.31, score=46.4]; Helicase conserved C-terminal domain [PF00271.33, score=45.8]} {Human: ENSG00000108771, DHX58, DExH-box helicase 58, [Score=116, Expect=5e-26]} {Mouse: ENSMUSG00000017830, Dhx58, DEXH (Asp-Glu-X-His) box polypeptide 58, [Score=114, Expect=2e-25]} {Dmel: FBgn0034246, Dcr-2, Dicer-2, [Score=117, Expect=4e-26]} {Celegans: WBGene00000939, dcr-1, Endoribonuclease dcr-1, [Score=139, Expect=1e-32]} {Smed: dd_Smed_v6_5587_0_1, dd_Smed_v6_5587_0_1, [Score=160, Expect=5e-40]} {RNA1509_8601} {RNA1310_142} {RNA815_2367}
17. MligTC455_49298 754 15.72 Mlig455_031663

Neo: -

Age: -

CORO7-PAM16 0.968 0.968 - - - - - Mlig455_031663 {REF} {Length: 4719} {TRANSSPLICED} {Pfam: Type of WD40 repeat [PF16300.7, score=80.7]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=27.6]} {Human: ENSG00000103426, CORO7-PAM16, CORO7-PAM16 readthrough, [Score=215, Expect=6e-57]; ENSG00000282725, CORO7, coronin 7, [Score=215, Expect=2e-57]; ENSG00000278760, CORO7-PAM16, CORO7-PAM16 readthrough, [Score=215, Expect=6e-57]; ENSG00000262246, CORO7, coronin 7, [Score=215, Expect=2e-57]} {Mouse: ENSMUSG00000039637, Coro7, coronin 7, [RH, Score=197, Expect=2e-51]} {Dmel: FBgn0029903, pod1, [Score=162, Expect=2e-40]} {Celegans: WBGene00004075, pod-1, POD-1, [Score=107, Expect=2e-23]} {Smed: dd_Smed_v6_448_0_1, dd_Smed_v6_448_0_1, [Score=71.2, Expect=2e-12]} {RNA1509_15841, RNA1509_26131} {RNA1310_4360, RNA1509_26131} {RNA1509_26131, RNA815_17986}
18. MligTC455_26752 385 8.01 Mlig455_008992

Neo: -

Age: -

TCF7L1 0.963 0.963 - - - - - Mlig455_008992 {REF} {Length: 5247} {TRANSSPLICED} {Pfam: HMG (high mobility group) box [PF00505.21, score=76.2]; HMG-box domain [PF09011.12, score=32.7]} {Human: ENSG00000152284, TCF7L1, transcription factor 7 like 1, [RH, Score=148, Expect=1e-37]; ENSG00000138795, LEF1, lymphoid enhancer binding factor 1, [RH, Score=145, Expect=6e-38]} {Mouse: ENSMUSG00000055799, Tcf7l1, transcription factor 7 like 1 (T cell specific, HMG box), [RH, Score=149, Expect=3e-38]; ENSMUSG00000027985, Lef1, lymphoid enhancer binding factor 1, [RH, Score=145, Expect=3e-38]} {Dmel: FBgn0085432, pan, pangolin, [RH, Score=150, Expect=5e-38]} {Celegans: WBGene00004077, pop-1, [RH, Score=108, Expect=4e-25]} {Smed: dd_Smed_v6_9140_0_1, dd_Smed_v6_9140_0_1, [RH, Score=157, Expect=1e-40]} {RNA1509_11661} {RNA1310_5451.3, RNA1509_11661} {RNA1509_11661, RNA815_18426}
19. MligTC455_50262 320 6.67 Mlig455_019038

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.470

TARBP2 0.963 0.963 - - - - - Mlig455_019038 {REF} {Length: 1661} {TRANSSPLICED} {Pfam: Double-stranded RNA binding motif [PF00035.28, score=62.0]; Staufen C-terminal domain [PF16482.7, score=26.1]} {Human: ENSG00000139546, TARBP2, TARBP2, RISC loading complex RNA binding subunit, [RH, Score=62.0, Expect=2e-11]} {Mouse: ENSMUSG00000023051, Tarbp2, TARBP2, RISC loading complex RNA binding subunit, [Score=81.6, Expect=1e-17]} {Dmel: FBgn0032515, loqs, loquacious, [RH, Score=121, Expect=2e-30]} {Smed: dd_Smed_v6_9213_0_1, dd_Smed_v6_9213_0_1, [RH, Score=157, Expect=1e-44]} {RNA1509_37226} {RNA1310_1441.1} {RNA815_48096}
20. MligTC455_50263 574 11.97 Mlig455_055664

Neo: -

Age: Down-Down-Up

TARBP2 0.963 0.963 - - - - - Mlig455_055664 {REF} {Length: 1663} {TRANSSPLICED} {Pfam: Double-stranded RNA binding motif [PF00035.28, score=62.0]; Staufen C-terminal domain [PF16482.7, score=26.1]} {Human: ENSG00000139546, TARBP2, TARBP2, RISC loading complex RNA binding subunit, [RH, Score=62.0, Expect=2e-11]} {Mouse: ENSMUSG00000023051, Tarbp2, TARBP2, RISC loading complex RNA binding subunit, [Score=81.6, Expect=1e-17]} {Dmel: FBgn0032515, loqs, loquacious, [RH, Score=121, Expect=2e-30]} {Smed: dd_Smed_v6_9213_0_1, dd_Smed_v6_9213_0_1, [RH, Score=157, Expect=1e-44]} {RNA1509_37226} {RNA1310_1441.1, RNA1509_37226} {RNA1509_37226, RNA815_48096}
21. MligTC455_45335 1483 30.89 Mlig455_048638, Mlig455_068862

Neo: -

Age: Up-Down-Up

D2HGDH 0.961 - - - - 0.961 -

Mlig455_048638 {REF} {Length: 2059} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=137.0]; FAD binding domain [PF01565.25, score=126.8]} {Human: ENSG00000180902, D2HGDH, D-2-hydroxyglutarate dehydrogenase, [Score=405, Expect=4e-136]} {Mouse: ENSMUSG00000073609, D2hgdh, D-2-hydroxyglutarate dehydrogenase, [Score=411, Expect=3e-138]} {Dmel: FBgn0023507, D2hgdh, D-2-hydroxyglutaric acid dehydrogenase, [Score=371, Expect=1e-122]} {Celegans: WBGene00010055, F54D5.12, [Score=318, Expect=9e-103]} {Smed: dd_Smed_v6_6440_0_1, dd_Smed_v6_6440_0_1, [Score=413, Expect=1e-139]} {RNA1509_50905} {RNA1310_17895.1} {RNA815_10343.1}

Mlig455_068862 {REF} {Length: 1918} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=136.4]; FAD binding domain [PF01565.25, score=126.8]} {Human: ENSG00000180902, D2HGDH, D-2-hydroxyglutarate dehydrogenase, [Score=406, Expect=3e-136]} {Mouse: ENSMUSG00000073609, D2hgdh, D-2-hydroxyglutarate dehydrogenase, [Score=411, Expect=3e-138]} {Dmel: FBgn0023507, D2hgdh, D-2-hydroxyglutaric acid dehydrogenase, [Score=370, Expect=1e-122]} {Celegans: WBGene00010055, F54D5.12, [Score=318, Expect=8e-103]} {Smed: dd_Smed_v6_6440_0_1, dd_Smed_v6_6440_0_1, [Score=413, Expect=1e-139]} {RNA1509_50905} {RNA1310_17895.1} {RNA815_10343.1}
22. MligTC455_26743 705 14.69 Mlig455_024357, Mlig455_024472

Neo: -

Age: -

TBC1D10B 0.96 0.960 - - - - -

Mlig455_024357 {REF} {Length: 4906} {TRANSSPLICED} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=170.0]} {Human: ENSG00000169221, TBC1D10B, TBC1 domain family member 10B, [RH, Score=292, Expect=2e-91]; ENSG00000099992, TBC1D10A, TBC1 domain family member 10A, [RH, Score=290, Expect=1e-93]} {Mouse: ENSMUSG00000042492, Tbc1d10b, TBC1 domain family, member 10b, [RH, Score=293, Expect=6e-92]; ENSMUSG00000034412, Tbc1d10a, TBC1 domain family, member 10a, [RH, Score=291, Expect=2e-94]} {Dmel: FBgn0037917, wkd, whacked, [RH, Score=305, Expect=1e-101]} {Celegans: WBGene00019915, tbc-10, TBC (Tre-2/Bub2/Cdc16) domain family, [RH, Score=265, Expect=4e-85]} {Smed: dd_Smed_v6_5522_0_2, dd_Smed_v6_5522_0_2, [RH, Score=296, Expect=5e-99]} {RNA1509_33058, RNA1509_44404, RNA1509_46690, RNA1509_47929, RNA1509_52044} {RNA1310_23976, RNA1509_33058, RNA1509_44404, RNA1509_46690, RNA1509_47929, RNA1509_52044} {RNA1509_33058, RNA1509_44404, RNA1509_46690, RNA1509_47929, RNA1509_52044, RNA815_23173}

Mlig455_024472 {REF} {Length: 4490} {TRANSSPLICED} {Pfam: Rab-GTPase-TBC domain [PF00566.20, score=170.0]} {Human: ENSG00000169221, TBC1D10B, TBC1 domain family member 10B, [RH, Score=292, Expect=2e-91]; ENSG00000099992, TBC1D10A, TBC1 domain family member 10A, [RH, Score=290, Expect=1e-93]} {Mouse: ENSMUSG00000042492, Tbc1d10b, TBC1 domain family, member 10b, [RH, Score=293, Expect=6e-92]; ENSMUSG00000034412, Tbc1d10a, TBC1 domain family, member 10a, [RH, Score=291, Expect=2e-94]} {Dmel: FBgn0037917, wkd, whacked, [RH, Score=305, Expect=1e-101]} {Celegans: WBGene00019915, tbc-10, TBC (Tre-2/Bub2/Cdc16) domain family, [RH, Score=265, Expect=4e-85]} {Smed: dd_Smed_v6_5522_0_2, dd_Smed_v6_5522_0_2, [RH, Score=296, Expect=5e-99]} {RNA1509_37963, RNA1509_40386} {RNA1310_23976, RNA1509_37963} {RNA1509_37963, RNA815_23173}
23. MligTC455_37141 1927 40.15 Mlig455_024772, Mlig455_058327

Neo: -

Age: -

PRKAA2 0.96 - - - - 0.960 -

Mlig455_024772 {REF} {Length: 2305} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=118.8]; Adenylate sensor of SNF1-like protein kinase [PF16579.7, score=32.9]; Kinase-like [PF14531.8, score=28.7]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]} {Human: ENSG00000162409, PRKAA2, protein kinase AMP-activated catalytic subunit alpha 2, [Score=532, Expect=0.0]} {Mouse: ENSMUSG00000028518, Prkaa2, protein kinase, AMP-activated, alpha 2 catalytic subunit, [Score=522, Expect=0.0]; ENSMUSG00000050697, Prkaa1, protein kinase, AMP-activated, alpha 1 catalytic subunit, [Score=497, Expect=3e-173]} {Dmel: FBgn0023169, AMPKalpha, AMP-activated protein kinase alpha subunit, [Score=503, Expect=3e-175]} {Celegans: WBGene00020142, aak-2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, [Score=476, Expect=5e-165]} {Smed: dd_Smed_v6_2538_0_1, dd_Smed_v6_2538_0_1, [Score=534, Expect=0.0]} {RNA1509_3781} {RNA1310_5604.1, RNA1509_3781} {RNA1509_3781, RNA815_2493.1}

Mlig455_058327 {REF} {Length: 2308} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=208.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=118.8]; Adenylate sensor of SNF1-like protein kinase [PF16579.7, score=32.9]; Kinase-like [PF14531.8, score=28.7]; ABC1 atypical kinase-like domain [PF03109.18, score=22.5]} {Human: ENSG00000162409, PRKAA2, protein kinase AMP-activated catalytic subunit alpha 2, [Score=532, Expect=0.0]} {Mouse: ENSMUSG00000028518, Prkaa2, protein kinase, AMP-activated, alpha 2 catalytic subunit, [Score=522, Expect=0.0]; ENSMUSG00000050697, Prkaa1, protein kinase, AMP-activated, alpha 1 catalytic subunit, [Score=497, Expect=3e-173]} {Dmel: FBgn0023169, AMPKalpha, AMP-activated protein kinase alpha subunit, [Score=503, Expect=3e-175]} {Celegans: WBGene00020142, aak-2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, [Score=476, Expect=5e-165]} {Smed: dd_Smed_v6_2538_0_1, dd_Smed_v6_2538_0_1, [Score=534, Expect=0.0]} {RNA1509_3781} {RNA1310_5604.1} {RNA815_2493.1}
24. MligTC455_22932 524 10.92 Mlig455_040338, Mlig455_050278, Mlig455_050286

Neo: -

Age: -

AFTPH 0.959 0.959 - - - - -

Mlig455_040338 {REF} {Length: 4174} {Pfam: Clathrin-binding box of Aftiphilin, vesicle trafficking [PF15045.8, score=27.2]} {Human: ENSG00000119844, AFTPH, aftiphilin, [RH, Score=93.6, Expect=2e-19]} {Mouse: ENSMUSG00000049659, Aftph, aftiphilin, [RH, Score=97.8, Expect=4e-21]} {Celegans: WBGene00021561, Y45G5AM.9, [RH, Score=67.0, Expect=1e-11]} {Smed: dd_Smed_v6_9369_0_1, dd_Smed_v6_9369_0_1, [RH, Score=60.5, Expect=1e-09]} {RNA1509_57161} {RNA1310_8393} {RNA815_5478}

Mlig455_050278 {REF} {Length: 214} {NoTransDecoderORF} {RNA1509_43578} {RNA1310_64530} {RNA815_33798}

Mlig455_050286 {REF} {Length: 2370} {Pfam: Clathrin-binding box of Aftiphilin, vesicle trafficking [PF15045.8, score=25.4]} {Human: ENSG00000119844, AFTPH, aftiphilin, [RH, Score=93.6, Expect=3e-21]} {Mouse: ENSMUSG00000049659, Aftph, aftiphilin, [RH, Score=97.1, Expect=1e-22]} {Celegans: WBGene00021561, Y45G5AM.9, [RH, Score=63.9, Expect=1e-11]} {Smed: dd_Smed_v6_9369_0_1, dd_Smed_v6_9369_0_1, [RH, Score=60.5, Expect=1e-10]} {RNA1509_43578, RNA1509_57161} {RNA1310_8393, RNA1509_43578} {RNA1509_43578, RNA815_5478}
25. MligTC455_27433 182 3.78 Mlig455_012707

Neo: -

Age: logFC(26M/2M)=-0.487

TRERF1 0.958 - - - - - 0.958 Mlig455_012707 {REF} {Length: 6713} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=63.8]; C2H2-type zinc finger [PF13894.8, score=37.0]; ELM2 domain [PF01448.26, score=27.9]; Zinc-finger double domain [PF13465.8, score=25.8]; C2H2-type zinc finger [PF13912.8, score=23.1]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=22.3]} {Human: ENSG00000124496, TRERF1, transcriptional regulating factor 1, [RH, Score=118, Expect=2e-26]; ENSG00000118156, ZNF541, zinc finger protein 541, [RH, Score=115, Expect=3e-25]} {Mouse: ENSMUSG00000116235, Trerf1, transcriptional regulating factor 1, [RH, Score=118, Expect=2e-26]; ENSMUSG00000078796, Zfp541, zinc finger protein 541, [RH, Score=114, Expect=4e-25]} {Dmel: FBgn0037698, CG16779, [RH, Score=124, Expect=3e-28]} {Celegans: WBGene00010012, saeg-1, Suppressor of activated egl-4 protein 1, [RH, Score=119, Expect=3e-27]} {Smed: dd_Smed_v6_6649_0_1, dd_Smed_v6_6649_0_1, [RH, Score=198, Expect=1e-51]} {RNA1509_22271} {RNA1310_15660} {RNA815_14217}
26. MligTC455_24158 1111 23.15 Mlig455_019516

Neo: -

Age: -

GCLC 0.957 - - - - 0.957 - Mlig455_019516 {REF} {Length: 3133} {TRANSSPLICED} {Pfam: Glutamate-cysteine ligase [PF03074.18, score=539.5]} {Human: ENSG00000001084, GCLC, glutamate-cysteine ligase catalytic subunit, [RH, Score=702, Expect=0.0]} {Mouse: ENSMUSG00000032350, Gclc, glutamate-cysteine ligase, catalytic subunit, [RH, Score=701, Expect=0.0]} {Dmel: FBgn0040319, Gclc, Glutamate-cysteine ligase catalytic subunit, [RH, Score=629, Expect=0.0]} {Celegans: WBGene00001527, gcs-1, Glutamate--cysteine ligase, [RH, Score=644, Expect=0.0]} {Smed: dd_Smed_v6_6745_0_1, dd_Smed_v6_6745_0_1, [RH, Score=701, Expect=0.0]} {RNA1509_25502, RNA1509_35581, RNA1509_3811} {RNA1310_4185, RNA1509_25502, RNA1509_35581, RNA1509_3811} {RNA1509_25502, RNA1509_35581, RNA1509_3811, RNA815_1399.1}
27. MligTC455_22931 253 5.28 Mlig455_040333

Neo: -

Age: -

0.956 0.956 - - - - - Mlig455_040333 {REF} {Length: 1309} {NoTransDecoderORF} {RNA1509_43578} {RNA1310_75006} {RNA815_33798}
28. MligTC455_32358 639 13.32 Mlig455_047088

Neo: -

Age: -

SEMA4D 0.956 0.956 - - - - - Mlig455_047088 {REF} {Length: 3251} {TRANSSPLICED} {Pfam: Sema domain [PF01403.21, score=90.1]} {Human: ENSG00000187764, SEMA4D, semaphorin 4D, [RH, Score=84.7, Expect=3e-16]} {Mouse: ENSMUSG00000021451, Sema4d, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, [Score=86.7, Expect=7e-17]} {RNA1509_27613} {RNA1310_4753.1} {RNA815_4966.1}
29. MligTC455_49480 3325 69.28 Mlig455_061462

Neo: -

Age: -

Regeneration-upregulated BL: 1.148

Regeneration-enriched BL: 1.148

RBM39 0.956 - - - - 0.956 - Mlig455_061462 {REF} {Length: 2374} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=136.6]; linker between RRM2 and RRM3 domains in RBM39 protein [PF15519.8, score=60.2]} {Human: ENSG00000131051, RBM39, RNA binding motif protein 39, [RH, Score=363, Expect=1e-118]} {Mouse: ENSMUSG00000027620, Rbm39, RNA binding motif protein 39, [RH, Score=363, Expect=9e-119]} {Dmel: FBgn0031883, Caper, [RH, Score=342, Expect=1e-109]} {Celegans: WBGene00021921, Y55F3AM.3, [RH, Score=258, Expect=6e-78]} {Smed: dd_Smed_v6_1932_0_1, dd_Smed_v6_1932_0_1, [RH, Score=276, Expect=2e-86]} {RNA1509_4239, RNA1509_43417, RNA1509_9704} {RNA1310_3908, RNA1509_4239, RNA1509_43417} {RNA1509_4239, RNA1509_43417, RNA815_1081.1}
30. MligTC455_25047 135 2.82 Mlig455_041213

Neo: -

Age: -

RNF31 0.955 0.955 - - - - - Mlig455_041213 {REF} {Length: 3533} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=39.2]; E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=27.3]; Domain of unknown function (DUF4573) [PF15140.8, score=21.0]} {Human: ENSG00000285152, RNF31, ring finger protein 31, [Score=188, Expect=2e-49]; ENSG00000092098, RNF31, ring finger protein 31, [Score=188, Expect=2e-49]; ENSG00000284845, AL136295.10, novel transcript, [Score=185, Expect=3e-50]; ENSG00000259529, AL136295.5, novel transcript, [Score=185, Expect=3e-50]} {Mouse: ENSMUSG00000047098, Rnf31, ring finger protein 31, [Score=184, Expect=3e-48]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=171, Expect=7e-44]} {Smed: dd_Smed_v6_4074_0_1, dd_Smed_v6_4074_0_1, [RH, Score=134, Expect=1e-32]} {RNA1509_18940} {RNA1310_17723.1} {RNA815_23151}
31. MligTC455_39286 380 7.91 Mlig455_027039

Neo: Int S/G2/M

Age: -

Region-enriched R5: 2.104/0.00108

0.955 0.955 - - - - - Mlig455_027039 {REF} {Length: 2237} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_25432} {RNA1310_22232} {RNA815_10193}
32. MligTC455_07779 143 2.98 Mlig455_022087

Neo: -

Age: Up-Down-Up

UBA3 0.954 0.954 - - - - - Mlig455_022087 {REF} {Length: 2132} {TRANSSPLICED} {Human: ENSG00000144744, UBA3, ubiquitin like modifier activating enzyme 3, [Score=114, Expect=3e-30]} {Mouse: ENSMUSG00000030061, Uba3, ubiquitin-like modifier activating enzyme 3, [Score=111, Expect=2e-29]} {Dmel: FBgn0263697, Uba3, Ubiquitin activating enzyme 3, [Score=104, Expect=4e-27]} {Celegans: WBGene00004341, rfl-1, NEDD8-activating enzyme E1 catalytic subunit, [Score=100, Expect=8e-26]} {Smed: dd_Smed_v6_5739_0_1, dd_Smed_v6_5739_0_1, [Score=118, Expect=2e-32]} {RNA1509_32078} {RNA1310_15788.2} {RNA815_7861}
33. MligTC455_07780 144 2.99 Mlig455_053625

Neo: -

Age: -

UBA3 0.953 0.953 - - - - - Mlig455_053625 {REF} {Length: 2608} {TRANSSPLICED} {Pfam: ThiF family [PF00899.23, score=193.1]; E2 binding domain [PF08825.12, score=37.3]; Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [PF14732.8, score=23.1]} {Human: ENSG00000144744, UBA3, ubiquitin like modifier activating enzyme 3, [RH, Score=441, Expect=5e-152]} {Mouse: ENSMUSG00000030061, Uba3, ubiquitin-like modifier activating enzyme 3, [RH, Score=438, Expect=2e-151]} {Dmel: FBgn0263697, Uba3, Ubiquitin activating enzyme 3, [RH, Score=379, Expect=2e-128]} {Celegans: WBGene00004341, rfl-1, NEDD8-activating enzyme E1 catalytic subunit, [RH, Score=372, Expect=6e-126]} {Smed: dd_Smed_v6_5739_0_1, dd_Smed_v6_5739_0_1, [RH, Score=426, Expect=2e-147]} {RNA1509_12385, RNA1509_32078} {RNA1310_15788.2, RNA1509_12385, RNA1509_32078} {RNA1509_12385, RNA1509_32078, RNA815_7861}
34. MligTC455_26751 276 5.74 Mlig455_008891

Neo: -

Age: -

0.951 0.951 - - - - - Mlig455_008891 {REF} {Length: 2748} {Pfam: Domain of unknown function (DUF4081) [PF13312.8, score=28.5]} {RNA1509_43903} {RNA1310_20783} {RNA815_29971}
35. MligTC455_26753 217 4.52 Mlig455_016529

Neo: Int S/G2/M

Age: -

CCNL2 0.95 0.950 - - - - - Mlig455_016529 {REF} {Length: 5849} {TRANSSPLICED} {Pfam: Cyclin, N-terminal domain [PF00134.25, score=41.0]} {Human: ENSG00000221978, CCNL2, cyclin L2, [RH, Score=321, Expect=1e-99]} {Mouse: ENSMUSG00000029068, Ccnl2, cyclin L2, [RH, Score=315, Expect=1e-97]; ENSMUSG00000027829, Ccnl1, cyclin L1, [RH, Score=302, Expect=2e-92]} {Dmel: FBgn0040394, CG16903, [RH, Score=302, Expect=3e-92]} {Celegans: WBGene00000876, cyl-1, CYclin L; Cyclin L, [RH, Score=233, Expect=1e-67]} {Smed: dd_Smed_v6_1900_0_7, dd_Smed_v6_1900_0_7, [RH, Score=263, Expect=8e-79]} {RNA1509_47826} {RNA1310_20783} {RNA815_21972}

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