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Results for MligTC455_47520

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_47520 112 2.32 Mlig455_055872

Neo: -

Age: -

TTLL4 Mlig455_055872 {REF} {Length: 5195} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=278.3]; YheC/D like ATP-grasp [PF14398.8, score=32.9]} {Human: ENSG00000135912, TTLL4, tubulin tyrosine ligase like 4, [Score=391, Expect=6e-118]} {Mouse: ENSMUSG00000033257, Ttll4, tubulin tyrosine ligase-like family, member 4, [Score=373, Expect=2e-111]} {Dmel: FBgn0026147, CG16833, [Score=343, Expect=1e-103]} {Celegans: WBGene00014232, ttll-4, Tubulin polyglutamylase ttll-4, [Score=257, Expect=2e-74]} {Smed: dd_Smed_v6_17034_0_1, dd_Smed_v6_17034_0_1, [Score=431, Expect=2e-133]} {RNA1509_16750} {RNA1310_2257, RNA1509_16750} {RNA1509_16750, RNA815_2812}

Cumulative graph for MligTC455_47520

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 2.268 2.086 0.24595 0.89197
RegionR2 1.125 2.086 0.23419 0.60740
RegionR3 -1.939 2.086 0.99858 1.00000
RegionR4 0.82 2.086 0.35660 0.67913
RegionR5 0.728 2.086 0.31207 0.65088
RegionR6 0.044 2.086 0.77768 1.00000
RegionR7 2.027 2.086 0.02588 0.30223
RegionR8 -5.071 2.086 0.10127 0.59625

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -6.158 2.086 0.23354 0.96326
RegenerationR2 -0.043 2.086 0.93857 1.00000
RegenerationR3 1.913 2.086 0.02977 0.31024
RegenerationR4 -0.348 2.086 0.61794 0.92002
RegenerationR5 -0.683 2.086 0.24760 0.68109
RegenerationR6 -0.342 2.086 0.66514 0.90615
RegenerationBL 0.604 2.086 0.64404 0.98241
RegenerationTP -3.42 2.086 1.00000 1.00000


Genes with expression patterns similar to MligTC455_47520

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_47520 112 2.32 Mlig455_055872

Neo: -

Age: -

TTLL4 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_055872 {REF} {Length: 5195} {Pfam: Tubulin-tyrosine ligase family [PF03133.17, score=278.3]; YheC/D like ATP-grasp [PF14398.8, score=32.9]} {Human: ENSG00000135912, TTLL4, tubulin tyrosine ligase like 4, [Score=391, Expect=6e-118]} {Mouse: ENSMUSG00000033257, Ttll4, tubulin tyrosine ligase-like family, member 4, [Score=373, Expect=2e-111]} {Dmel: FBgn0026147, CG16833, [Score=343, Expect=1e-103]} {Celegans: WBGene00014232, ttll-4, Tubulin polyglutamylase ttll-4, [Score=257, Expect=2e-74]} {Smed: dd_Smed_v6_17034_0_1, dd_Smed_v6_17034_0_1, [Score=431, Expect=2e-133]} {RNA1509_16750} {RNA1310_2257, RNA1509_16750} {RNA1509_16750, RNA815_2812}
2. MligTC455_51850 175 3.64 Mlig455_046816, Mlig455_069969

Neo: -

Age: Down-Up-Up

2.468 - - - 0.741 0.962 0.765

Mlig455_046816 {REF} {Length: 3750} {RNA1509_35209} {RNA1310_5234} {RNA815_10649}

Mlig455_069969 {REF} {Length: 4802} {RNA1509_12681, RNA1509_35209, RNA1509_54194} {RNA1310_5234, RNA1509_12681, RNA1509_54194} {RNA1509_12681, RNA1509_54194, RNA815_10649}
3. MligTC455_45557 629 13.1 Mlig455_015721

Neo: -

Age: -

Region-enriched R2: 1.212/0.04087

DYNLT1 2.455 - - 0.759 - 0.951 0.745 Mlig455_015721 {REF} {Length: 1742} {TRANSSPLICED} {Pfam: Tctex-1 family [PF03645.15, score=89.2]} {Human: ENSG00000146425, DYNLT1, dynein light chain Tctex-type 1, [RH, Score=165, Expect=5e-49]} {Mouse: ENSMUSG00000092074, Dynlt1a, dynein light chain Tctex-type 1A, [RH, Score=161, Expect=8e-48]; ENSMUSG00000095677, Dynlt1f, dynein light chain Tctex-type 1F, [RH, Score=161, Expect=8e-48]; ENSMUSG00000000579, Dynlt1c, dynein light chain Tctex-type 1C, [RH, Score=161, Expect=8e-48]; ENSMUSG00000096255, Dynlt1b, dynein light chain Tctex-type 1B, [RH, Score=161, Expect=8e-48]} {Dmel: FBgn0024432, Dlc90F, Dynein light chain 90F, [Score=138, Expect=3e-39]} {Smed: dd_Smed_v6_1166_0_1, dd_Smed_v6_1166_0_1, [RH, Score=171, Expect=5e-52]} {RNA1509_42217} {RNA1310_25091} {RNA815_10285.1}
4. MligTC455_49533 178 3.71 Mlig455_039575, Mlig455_039589

Neo: -

Age: -

Region-enriched R2: 3.871/0.04295

MOV10L1 1.804 - - - - 0.959 0.845

Mlig455_039575 {REF} {Length: 4060} {TRANSSPLICED} {Pfam: AAA domain [PF13086.8, score=110.5]; AAA domain [PF13087.8, score=72.8]; AAA domain [PF13604.8, score=53.4]; AAA domain [PF13245.8, score=35.2]; Type III restriction enzyme, res subunit [PF04851.17, score=25.1]; AAA domain [PF13401.8, score=19.1]; UvrD/REP helicase N-terminal domain [PF00580.23, score=18.7]} {Human: ENSG00000073146, MOV10L1, Mov10 like RISC complex RNA helicase 1, [Score=386, Expect=5e-115]; ENSG00000155363, MOV10, Mov10 RISC complex RNA helicase, [Score=375, Expect=3e-113]} {Mouse: ENSMUSG00000015365, Mov10l1, Moloney leukemia virus 10-like 1, [Score=380, Expect=3e-113]; ENSMUSG00000002227, Mov10, Moloney leukemia virus 10, [Score=372, Expect=2e-111]} {Dmel: FBgn0041164, armi, armitage, [Score=377, Expect=6e-112]} {Celegans: WBGene00004880, smg-2, Regulator of nonsense transcripts 1, [Score=137, Expect=1e-32]} {Smed: dd_Smed_v6_2121_1_1, dd_Smed_v6_2121_1_1, [Score=543, Expect=7e-175]} {RNA1509_13793} {RNA1310_3451.1} {RNA815_11722}

Mlig455_039589 {REF} {Length: 4433} {TRANSSPLICED} {Pfam: AAA domain [PF13087.8, score=126.9]; AAA domain [PF13086.8, score=110.4]; AAA domain [PF13604.8, score=53.4]; AAA domain [PF13245.8, score=35.5]; Type III restriction enzyme, res subunit [PF04851.17, score=25.3]; AAA domain [PF13401.8, score=19.1]; UvrD/REP helicase N-terminal domain [PF00580.23, score=18.6]} {Human: ENSG00000073146, MOV10L1, Mov10 like RISC complex RNA helicase 1, [RH, Score=443, Expect=9e-136]; ENSG00000155363, MOV10, Mov10 RISC complex RNA helicase, [RH, Score=421, Expect=7e-130]} {Mouse: ENSMUSG00000015365, Mov10l1, Moloney leukemia virus 10-like 1, [RH, Score=436, Expect=2e-133]; ENSMUSG00000002227, Mov10, Moloney leukemia virus 10, [RH, Score=417, Expect=3e-128]} {Dmel: FBgn0041164, armi, armitage, [RH, Score=418, Expect=4e-127]} {Celegans: WBGene00004880, smg-2, Regulator of nonsense transcripts 1, [Score=165, Expect=4e-41]} {Smed: dd_Smed_v6_2121_1_1, dd_Smed_v6_2121_1_1, [RH, Score=583, Expect=0.0]} {RNA1509_13793} {RNA1310_3451.1} {RNA815_11722}
5. MligTC455_53275 60 1.25 Mlig455_033794

Neo: -

Age: -

GLI3 1.771 - - - 0.810 0.961 - Mlig455_033794 {REF} {Length: 2359} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=22.4]} {Human: ENSG00000106571, GLI3, GLI family zinc finger 3, [Score=82.4, Expect=1e-15]; ENSG00000111087, GLI1, GLI family zinc finger 1, [Score=80.1, Expect=5e-15]; ENSG00000074047, GLI2, GLI family zinc finger 2, [Score=79.0, Expect=2e-14]} {Mouse: ENSMUSG00000021318, Gli3, GLI-Kruppel family member GLI3, [Score=82.8, Expect=7e-16]; ENSMUSG00000025407, Gli1, GLI-Kruppel family member GLI1, [Score=80.5, Expect=3e-15]; ENSMUSG00000048402, Gli2, GLI-Kruppel family member GLI2, [Score=79.0, Expect=1e-14]} {Dmel: FBgn0004859, ci, cubitus interruptus, [Score=87.4, Expect=1e-17]} {Celegans: WBGene00006604, tra-1, Sex-determining transformer protein 1, [Score=61.2, Expect=2e-09]} {Smed: dd_Smed_v6_7470_0_1, dd_Smed_v6_7470_0_1, [Score=88.6, Expect=3e-18]} {RNA1509_45457, RNA1509_5991} {RNA1310_3099, RNA1509_45457} {RNA1509_45457, RNA815_10461.1}
6. MligTC455_52074 36 0.74 Mlig455_000653

Neo: -

Age: -

1.759 - - - 0.797 0.962 - Mlig455_000653 {REF} {Length: 2461} {NoTransDecoderORF} {RNA1310_118495}
7. MligTC455_16725 225 4.69 Mlig455_056078

Neo: -

Age: Up-Down-Down

PTEN 1.729 - - - - 0.977 0.752 Mlig455_056078 {REF} {Length: 4586} {TRANSSPLICED} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=72.2]; Dual specificity phosphatase, catalytic domain [PF00782.22, score=22.7]; Protein-tyrosine phosphatase [PF00102.29, score=18.5]} {Human: ENSG00000284792, PTEN, phosphatase and tensin homolog, [Score=269, Expect=2e-83]; ENSG00000171862, PTEN, phosphatase and tensin homolog, [Score=266, Expect=2e-84]} {Mouse: ENSMUSG00000013663, Pten, phosphatase and tensin homolog, [Score=266, Expect=1e-84]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=219, Expect=2e-66]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=150, Expect=5e-39]} {Smed: dd_Smed_v6_7478_0_1, dd_Smed_v6_7478_0_1, [RH, Score=230, Expect=5e-71]} {RNA1509_17397} {RNA1310_7531.2, RNA1509_17397} {RNA1509_17397, RNA815_4064}
8. MligTC455_16724 211 4.4 Mlig455_055966

Neo: -

Age: Up-Down-Up

PTEN 1.728 - - - - 0.955 0.773 Mlig455_055966 {REF} {Length: 4096} {TRANSSPLICED} {Pfam: C2 domain of PTEN tumour-suppressor protein [PF10409.11, score=72.2]} {Human: ENSG00000284792, PTEN, phosphatase and tensin homolog, [Score=265, Expect=1e-81]; ENSG00000171862, PTEN, phosphatase and tensin homolog, [Score=262, Expect=9e-83]} {Mouse: ENSMUSG00000013663, Pten, phosphatase and tensin homolog, [Score=262, Expect=6e-83]} {Dmel: FBgn0026379, Pten, Phosphatase and tensin homolog, [Score=214, Expect=3e-64]} {Celegans: WBGene00000913, daf-18, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18, [Score=147, Expect=1e-37]} {Smed: dd_Smed_v6_7478_0_1, dd_Smed_v6_7478_0_1, [RH, Score=225, Expect=6e-69]} {RNA1509_17397} {RNA1310_7531.2} {RNA815_4064}
9. MligTC455_00419 109 2.27 Mlig455_003934

Neo: -

Age: -

0.986 - - - - 0.986 - Mlig455_003934 {REF} {Length: 780} {NoTransDecoderORF} {RNA1509_46406} {RNA1310_72097} {RNA815_61152.1}
10. MligTC455_24813 19 0.39 Mlig455_033178

Neo: -

Age: -

0.981 - - - - 0.981 - Mlig455_033178 {REF} {Length: 1294} {NoTransDecoderORF}
11. MligTC455_04076 40 0.83 Mlig455_039207

Neo: -

Age: -

SHOC2 0.978 - - - - - 0.978 Mlig455_039207 {REF} {Length: 3742} {TRANSSPLICED} {Pfam: Leucine rich repeat [PF13855.8, score=240.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=136.1]; Leucine Rich Repeat [PF00560.35, score=38.2]; Leucine-rich repeat [PF14580.8, score=36.7]; BspA type Leucine rich repeat region (6 copies) [PF13306.8, score=19.5]} {Human: ENSG00000108061, SHOC2, SHOC2, leucine rich repeat scaffold protein, [Score=407, Expect=3e-134]} {Mouse: ENSMUSG00000024976, Shoc2, Shoc2, leucine rich repeat scaffold protein, [Score=410, Expect=1e-135]} {Dmel: FBgn0038504, Sur-8, [Score=422, Expect=1e-139]} {Celegans: WBGene00004929, soc-2, Leucine-rich repeat protein soc-2, [Score=393, Expect=1e-129]} {Smed: dd_Smed_v6_1909_0_1, dd_Smed_v6_1909_0_1, [Score=385, Expect=4e-126]} {RNA1509_19249} {RNA1310_7161.1} {RNA815_7354}
12. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

VASH2 0.977 - - - - 0.977 - Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
13. MligTC455_44782 1105 23.02 Mlig455_014607

Neo: -

Age: -

PGAM5 0.977 - - - - 0.977 - Mlig455_014607 {REF} {Length: 2581} {TRANSSPLICED} {Pfam: Histidine phosphatase superfamily (branch 1) [PF00300.24, score=74.1]} {Human: ENSG00000247077, PGAM5, PGAM family member 5, mitochondrial serine/threonine protein phosphatase, [Score=169, Expect=1e-50]} {Mouse: ENSMUSG00000029500, Pgam5, phosphoglycerate mutase family member 5, [Score=171, Expect=2e-51]} {Dmel: FBgn0023517, Pgam5, Phosphoglycerate mutase 5, [Score=151, Expect=7e-44]} {Celegans: WBGene00019941, pgam-5, Serine/threonine-protein phosphatase Pgam5, mitochondrial, [Score=164, Expect=4e-49]} {Smed: dd_Smed_v6_6361_0_1, dd_Smed_v6_6361_0_1, [Score=160, Expect=5e-48]} {RNA1509_10913} {RNA1310_28905, RNA1509_10913} {RNA1509_10913, RNA815_15585}
14. MligTC455_54125 957 19.94 Mlig455_000017

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.528/0.00489

SPEF1 0.976 - - - - 0.976 - Mlig455_000017 {REF} {Length: 1279} {TRANSSPLICED} {Pfam: CH-like domain in sperm protein [PF06294.13, score=114.7]; CAMSAP CH domain [PF11971.10, score=53.6]} {Human: ENSG00000101222, SPEF1, sperm flagellar 1, [RH, Score=172, Expect=1e-52]} {Mouse: ENSMUSG00000027329, Spef1, sperm flagellar 1, [RH, Score=180, Expect=3e-56]} {Dmel: FBgn0030722, CG12395, [Score=65.5, Expect=2e-12]} {Smed: dd_Smed_v6_5648_0_1, dd_Smed_v6_5648_0_1, [RH, Score=272, Expect=5e-93]} {RNA1509_17511, RNA1509_37707, RNA1509_9365} {RNA1310_25346.1, RNA1509_17511, RNA1509_37707, RNA1509_9365} {RNA1509_17511, RNA1509_37707, RNA1509_9365, RNA815_11607}
15. MligTC455_34852 681 14.19 Mlig455_040753, Mlig455_066786

Neo: -

Age: logFC(26M/2M)=-0.406

CAPN3, CAPN9 0.975 - - - - 0.975 -

Mlig455_040753 {REF} {Length: 2907} {Pfam: Calpain family cysteine protease [PF00648.23, score=389.3]; Calpain large subunit, domain III [PF01067.24, score=132.2]; EF hand [PF00036.34, score=31.5]; EF-hand domain pair [PF13833.8, score=24.3]; EF-hand domain [PF13405.8, score=23.5]} {Human: ENSG00000135773, CAPN9, calpain 9, [Score=541, Expect=0.0]; ENSG00000092529, CAPN3, calpain 3, [Score=540, Expect=0.0]} {Mouse: ENSMUSG00000079110, Capn3, calpain 3, [Score=534, Expect=0.0]; ENSMUSG00000031981, Capn9, calpain 9, [Score=525, Expect=1e-177]} {Dmel: FBgn0025866, CalpB, Calpain-B, [Score=566, Expect=0.0]} {Celegans: WBGene00000542, clp-1, Calpain clp-1, [Score=436, Expect=8e-143]} {Smed: dd_Smed_v6_1752_0_4, dd_Smed_v6_1752_0_4, [Score=724, Expect=0.0]} {RNA1509_45636} {RNA1310_9182} {RNA815_3486}

Mlig455_066786 {REF} {Length: 4477} {Pfam: Calpain family cysteine protease [PF00648.23, score=389.2]; Calpain large subunit, domain III [PF01067.24, score=132.2]; EF hand [PF00036.34, score=32.0]; EF-hand domain pair [PF13833.8, score=23.4]; EF-hand domain [PF13405.8, score=23.2]; EF hand [PF13202.8, score=18.8]} {Human: ENSG00000092529, CAPN3, calpain 3, [Score=542, Expect=0.0]; ENSG00000135773, CAPN9, calpain 9, [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000079110, Capn3, calpain 3, [Score=536, Expect=0.0]; ENSMUSG00000031981, Capn9, calpain 9, [Score=526, Expect=5e-178]} {Dmel: FBgn0025866, CalpB, Calpain-B, [Score=565, Expect=0.0]} {Celegans: WBGene00000542, clp-1, Calpain clp-1, [Score=436, Expect=2e-142]} {Smed: dd_Smed_v6_1752_0_2, dd_Smed_v6_1752_0_2, [Score=724, Expect=0.0]} {RNA1509_45636} {RNA1310_9182} {RNA815_3486}
16. MligTC455_24359 269 5.6 Mlig455_061470

Neo: -

Age: logFC(26M/2M)=-0.300

0.972 - - - - 0.972 - Mlig455_061470 {REF} {Length: 1541} {Pfam: Domain of unknown function (DUF4476) [PF14771.8, score=44.6]} {Smed: dd_Smed_v6_50605_0_1, dd_Smed_v6_50605_0_1, [RH, Score=189, Expect=6e-60]} {RNA1509_15325, RNA1509_47076} {RNA1310_24934.1, RNA1509_15325, RNA1509_47076} {RNA1509_15325, RNA1509_47076, RNA815_10915.1}
17. MligTC455_27638 969 20.19 Mlig455_022789

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.917

CLUAP1 0.972 - - - - 0.972 - Mlig455_022789 {REF} {Length: 2458} {Pfam: Clusterin-associated protein-1 [PF10234.11, score=358.0]} {Human: ENSG00000103351, CLUAP1, clusterin associated protein 1, [RH, Score=332, Expect=1e-110]} {Mouse: ENSMUSG00000014232, Cluap1, clusterin associated protein 1, [RH, Score=330, Expect=8e-110]} {Dmel: FBgn0031196, CG17599, [RH, Score=135, Expect=1e-34]} {Celegans: WBGene00001119, dyf-3, Clusterin-associated protein 1 homolog, [RH, Score=215, Expect=1e-65]} {Smed: dd_Smed_v6_8287_0_1, dd_Smed_v6_8287_0_1, [RH, Score=333, Expect=2e-110]} {RNA1509_14292, RNA1509_25335} {RNA1310_15979, RNA1509_14292, RNA1509_25335} {RNA1509_14292, RNA1509_25335, RNA815_6417.1}
18. MligTC455_53229 80 1.66 Mlig455_010127, Mlig455_010163

Neo: -

Age: -

0.972 - - - - - 0.972

Mlig455_010127 {REF} {Length: 1499} {Pfam: CD20-like family [PF04103.17, score=27.3]; SOCE-associated regulatory factor of calcium homoeostasis [PF06682.14, score=23.1]} {RNA1310_112810} {RNA815_19811}

Mlig455_010163 {REF} {Length: 1562} {Pfam: CD20-like family [PF04103.17, score=27.3]; SOCE-associated regulatory factor of calcium homoeostasis [PF06682.14, score=23.1]} {RNA1310_112810} {RNA815_19811}
19. MligTC455_25338 39 0.8 Mlig455_022036

Neo: -

Age: -

0.971 - - - - 0.971 - Mlig455_022036 {REF} {Length: 2818} {RNA1509_17997} {RNA1310_3871} {RNA815_1792.1}
20. MligTC455_30234 668 13.92 Mlig455_013688, Mlig455_020164, Mlig455_028077, Mlig455_036489, Mlig455_038238, Mlig455_049777, Mlig455_054410, Mlig455_055118, Mlig455_061417, Mlig455_068974, Mlig455_070511

Neo: -

Age: Up-Down-Down

PIF1 0.971 - - - - 0.971 -

Mlig455_013688 {REF} {Length: 3931} {Pfam: PIF1-like helicase [PF05970.16, score=335.0]; AAA domain [PF13604.8, score=47.7]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=1e-149]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=5e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_020164 {REF} {Length: 6683} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; AAA domain [PF13604.8, score=47.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.2]; AAA domain [PF13245.8, score=19.4]; Helicase [PF02689.16, score=16.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=3e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=479, Expect=5e-150]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_6950, RNA1509_5036} {RNA1509_5036, RNA815_356.1}

Mlig455_028077 {REF} {Length: 5927} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=333.5]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.6]; AAA domain [PF13604.8, score=45.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.1]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=121, Expect=2e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=3e-28]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=737, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_036489 {REF} {Length: 6279} {TRANSSPLICED} {Pfam: PIF1-like helicase [PF05970.16, score=335.1]; AAA domain [PF13604.8, score=47.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.1]; AAA domain [PF13245.8, score=19.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=6e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=6e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=509, Expect=7e-161]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=4e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_038238 {REF} {Length: 7170} {Pfam: PIF1-like helicase [PF05970.16, score=335.2]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.3]; AAA domain [PF13604.8, score=44.8]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.2]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=126, Expect=8e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=8e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=121, Expect=1e-27]} {Celegans: WBGene00021577, Y46B2A.2, [RH, Score=736, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_049777 {REF} {Length: 6866} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=175.0]; AAA domain [PF13604.8, score=43.6]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=123, Expect=8e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=117, Expect=2e-26]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=120, Expect=2e-27]} {Celegans: WBGene00019136, F59H6.5, [Score=760, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=1e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_054410 {REF} {Length: 3239} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=52.6]} {Celegans: WBGene00022692, ZK250.9, [Score=162, Expect=8e-44]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=45.1, Expect=8e-06]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_055118 {REF} {Length: 6779} {Pfam: PIF1-like helicase [PF05970.16, score=330.1]; Helitron helicase-like domain at N-terminus [PF14214.8, score=169.5]; AAA domain [PF13604.8, score=47.3]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.6]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=1e-28]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=122, Expect=5e-28]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=118, Expect=7e-27]} {Celegans: WBGene00018020, F33H12.6, [Score=733, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=113, Expect=2e-25]} {RNA1509_5036} {RNA1310_6950} {RNA815_356.1}

Mlig455_061417 {REF} {Length: 5410} {Pfam: Helitron helicase-like domain at N-terminus [PF14214.8, score=169.0]; PIF1-like helicase [PF05970.16, score=56.8]; AAA domain [PF13604.8, score=20.6]} {Celegans: WBGene00019136, F59H6.5, [Score=540, Expect=1e-169]} {Smed: dd_Smed_v6_91935_0_1, dd_Smed_v6_91935_0_1, [Score=70.5, Expect=4e-14]} {RNA1509_5036} {RNA1310_11485} {RNA815_356.1}

Mlig455_068974 {REF} {Length: 6598} {Pfam: PIF1-like helicase [PF05970.16, score=333.8]; Helitron helicase-like domain at N-terminus [PF14214.8, score=174.8]; AAA domain [PF13604.8, score=46.0]; UvrD-like helicase C-terminal domain [PF13538.8, score=25.3]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=127, Expect=5e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=120, Expect=3e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=123, Expect=2e-28]} {Celegans: WBGene00019136, F59H6.5, [RH, Score=771, Expect=0.0]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=2e-26]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}

Mlig455_070511 {REF} {Length: 6556} {Pfam: PIF1-like helicase [PF05970.16, score=335.6]; AAA domain [PF13604.8, score=48.1]; UvrD-like helicase C-terminal domain [PF13538.8, score=26.5]; AAA domain [PF13245.8, score=19.7]; Helicase [PF02689.16, score=16.9]} {Human: ENSG00000140451, PIF1, PIF1 5'-to-3' DNA helicase, [Score=125, Expect=4e-29]} {Mouse: ENSMUSG00000041064, Pif1, PIF1 5'-to-3' DNA helicase, [Score=119, Expect=1e-27]} {Dmel: FBgn0031540, Pif1, Pif1 ortholog, [Score=124, Expect=4e-29]} {Celegans: WBGene00019136, F59H6.5, [Score=391, Expect=6e-119]} {Smed: dd_Smed_v6_16842_0_1, dd_Smed_v6_16842_0_1, [Score=117, Expect=3e-27]} {RNA1509_5036} {RNA1310_728.1} {RNA815_356.1}
21. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

GRIA2 0.971 - - - - 0.971 -

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
22. MligTC455_28770 76 1.57 Mlig455_038434, Mlig455_069042

Neo: -

Age: -

0.97 - - - - 0.970 -

Mlig455_038434 {REF} {Length: 2508} {RNA1509_2515} {RNA1310_5479.1} {RNA815_3258.1}

Mlig455_069042 {REF} {Length: 1211} {NoTransDecoderORF} {RNA1509_22369, RNA1509_2515} {RNA1310_23566, RNA1509_22369} {RNA1509_22369, RNA815_3258.1}
23. MligTC455_51609 26 0.55 Mlig455_059418

Neo: -

Age: -

FAAH 0.969 - - - - - 0.969 Mlig455_059418 {REF} {Length: 2674} {Pfam: Amidase [PF01425.23, score=256.5]} {Human: ENSG00000117480, FAAH, fatty acid amide hydrolase, [Score=243, Expect=7e-72]} {Mouse: ENSMUSG00000034171, Faah, fatty acid amide hydrolase, [Score=252, Expect=2e-75]} {Dmel: FBgn0037547, CG7910, [Score=103, Expect=4e-23]} {Celegans: WBGene00019068, faah-3, Fatty Acid Amide Hydrolase homolog, [Score=266, Expect=3e-81]} {Smed: dd_Smed_v6_3298_0_1, dd_Smed_v6_3298_0_1, [Score=358, Expect=3e-116]} {RNA1310_26916} {RNA815_54676}
24. MligTC455_42242 1575 32.81 Mlig455_039054

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.378

PLXDC1 0.968 - - - - 0.968 - Mlig455_039054 {REF} {Length: 2567} {Human: ENSG00000161381, PLXDC1, plexin domain containing 1, [Score=109, Expect=1e-25]; ENSG00000120594, PLXDC2, plexin domain containing 2, [Score=107, Expect=7e-25]} {Mouse: ENSMUSG00000017417, Plxdc1, plexin domain containing 1, [Score=111, Expect=3e-26]; ENSMUSG00000026748, Plxdc2, plexin domain containing 2, [Score=107, Expect=1e-24]} {Dmel: FBgn0028331, l(1)G0289, lethal (1) G0289, [Score=97.8, Expect=1e-21]} {Celegans: WBGene00007982, pxd-1, PleXin Domain containing, [Score=112, Expect=6e-27]} {Smed: dd_Smed_v6_68203_0_1, dd_Smed_v6_68203_0_1, [Score=69.7, Expect=3e-14]} {RNA1509_49412, RNA1509_59319, RNA1509_8427} {RNA1310_7172.1, RNA1509_49412, RNA1509_59319} {RNA1509_49412, RNA1509_59319, RNA815_7707}
25. MligTC455_40794 268 5.57 Mlig455_017617

Neo: -

Age: -

0.967 - - - - 0.967 - Mlig455_017617 {REF} {Length: 2441} {TRANSSPLICED} {Pfam: RING-variant domain [PF12906.9, score=43.8]} {Dmel: FBgn0035983, CG4080, [Score=48.9, Expect=6e-06]} {RNA1509_39355} {RNA1310_22099.1} {RNA815_10655}
26. MligTC455_53093 333 6.93 Mlig455_002441

Neo: -

Age: Down-Up-Down

Region-enriched R2: 2.548/0.03843

SOX2 0.967 - - - - 0.967 - Mlig455_002441 {REF} {Length: 2143} {Pfam: HMG (high mobility group) box [PF00505.21, score=94.8]; HMG-box domain [PF09011.12, score=43.0]; Protein of unknown function (DUF2722) [PF10846.10, score=21.2]; VIT family [PF01988.21, score=18.8]} {Human: ENSG00000181449, SOX2, SRY-box 2, [RH, Score=179, Expect=6e-54]} {Mouse: ENSMUSG00000074637, Sox2, SRY (sex determining region Y)-box 2, [RH, Score=179, Expect=4e-54]} {Dmel: FBgn0029123, SoxN, SoxNeuro, [RH, Score=162, Expect=1e-44]} {Celegans: WBGene00004949, sox-2, Transcription factor sox-2, [Score=169, Expect=7e-51]} {Smed: dd_Smed_v6_13215_0_1, dd_Smed_v6_13215_0_1, [RH, Score=158, Expect=2e-44]} {RNA1509_11450} {RNA1310_8352} {RNA815_15989}
27. MligTC455_47962 1186 24.7 Mlig455_013564, Mlig455_013618

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.250

Region-enriched R4: 1.616/0.00549

0.964 - - - - 0.964 -

Mlig455_013564 {REF} {Length: 2951} {TRANSSPLICED} {RNA1509_26875, RNA1509_46492} {RNA1310_9354.2, RNA1509_26875, RNA1509_46492} {RNA1509_26875, RNA1509_46492, RNA815_12277.1}

Mlig455_013618 {REF} {Length: 3260} {TRANSSPLICED} {RNA1509_21658, RNA1509_26875} {RNA1310_9354.2, RNA1509_21658} {RNA1509_21658, RNA815_12277.2}
28. MligTC455_28518 184 3.84 Mlig455_068682

Neo: -

Age: Down-Down-Up

ANKRD50 0.962 - - - - 0.962 - Mlig455_068682 {REF} {Length: 5526} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=230.6]; Ankyrin repeats (many copies) [PF13637.8, score=137.6]; Ankyrin repeat [PF00023.32, score=109.8]; Ankyrin repeats (many copies) [PF13857.8, score=106.4]; Ankyrin repeat [PF13606.8, score=102.1]; Mab-21 protein [PF03281.16, score=30.7]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=158, Expect=1e-38]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=157, Expect=2e-38]} {Dmel: FBgn0261788, Ank2, Ankyrin 2, [Score=135, Expect=8e-33]} {Celegans: WBGene00006780, unc-44, AO66 ankyrin, [Score=134, Expect=1e-31]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [Score=140, Expect=6e-34]} {RNA1509_18101} {RNA1310_3035.1, RNA1509_18101} {RNA1509_18101, RNA815_4096}
29. MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

0.96 - - - - 0.960 -

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}
30. MligTC455_49709 228 4.74 Mlig455_024769, Mlig455_038951

Neo: -

Age: -

0.96 - - - - 0.960 -

Mlig455_024769 {REF} {Length: 560} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=104.8]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=1e-15]} {RNA1509_31268} {RNA1310_89323} {RNA815_51068}

Mlig455_038951 {REF} {Length: 1037} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=74.6]} {Smed: dd_Smed_v6_19123_0_4, dd_Smed_v6_19123_0_4, [Score=60.8, Expect=4e-10]} {RNA1509_31268} {RNA1310_10452.2} {RNA815_28501}
31. MligTC455_19869 157 3.27 Mlig455_046439, Mlig455_046468

Neo: -

Age: -

ZNF324 0.958 - - - - - 0.958

Mlig455_046439 {REF} {Length: 4053} {TRANSSPLICED} {Pfam: C2H2-type zinc finger [PF13894.8, score=58.9]; Zinc finger, C2H2 type [PF00096.28, score=53.6]; Zinc-finger double domain [PF13465.8, score=37.8]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=25.6]} {Human: ENSG00000083812, ZNF324, zinc finger protein 324, [Score=101, Expect=2e-21]} {Mouse: ENSMUSG00000004500, Zfp324, zinc finger protein 324, [Score=102, Expect=3e-22]} {Dmel: FBgn0033934, CG17385, [Score=82.8, Expect=6e-17]} {Celegans: WBGene00011066, ztf-15, Zinc finger putative Transcription Factor family, [RH, Score=67.0, Expect=4e-11]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [Score=83.2, Expect=1e-17]} {RNA1509_14607} {RNA1310_8185} {RNA815_15544}

Mlig455_046468 {REF} {Length: 1996} {TRANSSPLICED} {Pfam: C2H2-type zinc finger [PF13894.8, score=69.8]; Zinc finger, C2H2 type [PF00096.28, score=62.0]; Zinc-finger double domain [PF13465.8, score=46.4]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=36.2]; Drought induced 19 protein (Di19), zinc-binding [PF05605.14, score=25.2]} {Human: ENSG00000083812, ZNF324, zinc finger protein 324, [Score=96.3, Expect=4e-22]; ENSG00000116809, ZBTB17, zinc finger and BTB domain containing 17, [Score=92.0, Expect=3e-20]; ENSG00000189180, ZNF33A, zinc finger protein 33A, [Score=92.0, Expect=3e-20]; ENSG00000249471, ZNF324B, zinc finger protein 324B, [Score=91.7, Expect=3e-20]; ENSG00000188321, ZNF559, zinc finger protein 559, [Score=91.7, Expect=3e-20]} {Mouse: ENSMUSG00000045519, Zfp560, zinc finger protein 560, [Score=97.4, Expect=3e-22]; ENSMUSG00000004500, Zfp324, zinc finger protein 324, [Score=96.3, Expect=5e-22]} {Dmel: FBgn0037617, nom, numerous disordered muscles, [Score=77.0, Expect=8e-16]} {Celegans: WBGene00011066, ztf-15, Zinc finger putative Transcription Factor family, [RH, Score=67.4, Expect=2e-12]} {Smed: dd_Smed_v6_14824_0_1, dd_Smed_v6_14824_0_1, [Score=73.6, Expect=6e-15]} {RNA1509_40166, RNA1509_56111} {RNA1310_14502, RNA1509_40166, RNA1509_56111} {RNA1509_40166, RNA1509_56111, RNA815_25948}
32. MligTC455_27083 866 18.03 Mlig455_037117

Neo: -

Age: Up-Down-Up

0.958 - - - - 0.958 - Mlig455_037117 {REF} {Length: 3297} {Pfam: Lecithin retinol acyltransferase [PF04970.15, score=37.9]} {RNA1509_28043, RNA1509_40834, RNA1509_55948} {RNA1310_8839.1, RNA1509_28043, RNA1509_55948} {RNA1509_28043, RNA1509_55948, RNA815_3523.1}
33. MligTC455_28768 34 0.72 Mlig455_052093

Neo: -

Age: -

ANKRD50 0.958 - - - - 0.958 - Mlig455_052093 {REF} {Length: 3574} {Pfam: Ets-domain [PF00178.24, score=53.3]; Ankyrin repeats (many copies) [PF13637.8, score=47.0]; Ankyrin repeats (3 copies) [PF12796.9, score=42.5]; Ankyrin repeats (many copies) [PF13857.8, score=41.6]; Mab-21 protein [PF03281.16, score=37.4]; Ankyrin repeat [PF13606.8, score=35.3]; Ankyrin repeat [PF00023.32, score=32.5]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=71.6, Expect=6e-12]; ENSG00000170921, TANC2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=68.6, Expect=5e-11]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=69.7, Expect=2e-11]; ENSMUSG00000053580, Tanc2, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, [Score=68.2, Expect=6e-11]; ENSMUSG00000078487, Ankrd65, ankyrin repeat domain 65, [Score=66.6, Expect=5e-11]} {Dmel: FBgn0031473, CG3104, [Score=58.9, Expect=8e-09]} {Celegans: WBGene00185078, F40G9.17, [Score=52.0, Expect=5e-07]} {Smed: dd_Smed_v6_12936_0_1, dd_Smed_v6_12936_0_1, [Score=65.1, Expect=2e-10]} {RNA1509_26281} {RNA1310_4721} {RNA815_5358.1}
34. MligTC455_31427 429 8.94 Mlig455_024101

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.449

CHRNA3 0.957 - - - - 0.957 - Mlig455_024101 {REF} {Length: 2557} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=242.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=210.4]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=395, Expect=3e-131]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=377, Expect=1e-122]} {Mouse: ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=372, Expect=8e-121]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=363, Expect=2e-119]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=355, Expect=4e-116]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=443, Expect=2e-149]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=387, Expect=2e-128]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=382, Expect=2e-126]} {RNA1509_19028} {RNA1310_8041, RNA1509_19028} {RNA1509_19028, RNA815_11178}
35. MligTC455_36601 91 1.89 Mlig455_041320

Neo: -

Age: -

0.957 - - - - 0.957 - Mlig455_041320 {REF} {Length: 3476} {Pfam: Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=21.1]} {RNA1509_34867} {RNA1310_25426.1} {RNA815_30726}
36. MligTC455_42241 1556 32.43 Mlig455_022714

Neo: -

Age: Down-Up-Up

Region-enriched R4: 1.239/0.02808

PLXDC1 0.957 - - - - 0.957 - Mlig455_022714 {REF} {Length: 2263} {Human: ENSG00000161381, PLXDC1, plexin domain containing 1, [Score=110, Expect=5e-26]; ENSG00000120594, PLXDC2, plexin domain containing 2, [Score=105, Expect=7e-24]} {Mouse: ENSMUSG00000017417, Plxdc1, plexin domain containing 1, [Score=113, Expect=5e-27]} {Dmel: FBgn0028331, l(1)G0289, lethal (1) G0289, [Score=99.4, Expect=3e-22]} {Celegans: WBGene00007982, pxd-1, PleXin Domain containing, [Score=109, Expect=6e-26]} {Smed: dd_Smed_v6_68203_0_1, dd_Smed_v6_68203_0_1, [Score=68.9, Expect=6e-14]} {RNA1509_8427} {RNA1310_7172.1} {RNA815_7707}
37. MligTC455_04021 34 0.7 Mlig455_036549, Mlig455_057818

Neo: -

Age: -

0.956 - - - - 0.956 -

Mlig455_036549 {REF} {Length: 1886} {Pfam: RNase H [PF00075.26, score=46.3]; Reverse transcriptase-like [PF13456.8, score=20.6]} {RNA1310_118653}

Mlig455_057818 {REF} {Length: 1933} {Pfam: RNase H [PF00075.26, score=46.3]; Reverse transcriptase-like [PF13456.8, score=20.6]} {RNA1310_82648}
38. MligTC455_22792 813 16.94 Mlig455_006911

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=0.573

PPP1R10 0.956 - - - - 0.956 - Mlig455_006911 {REF} {Length: 4431} {TRANSSPLICED} {tRNA: Val(CAC),pseudo, score=34.5} {Pfam: TFIIS helical bundle-like domain [PF08711.13, score=20.9]; Negative regulator of genetic competence (MecA) [PF05389.14, score=18.7]} {Human: ENSG00000204569, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000230995, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000238104, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000235291, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000206489, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000227804, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]; ENSG00000231737, PPP1R10, protein phosphatase 1 regulatory subunit 10, [RH, Score=98.6, Expect=2e-20]} {Mouse: ENSMUSG00000039220, Ppp1r10, protein phosphatase 1, regulatory subunit 10, [RH, Score=95.1, Expect=2e-19]} {Dmel: FBgn0053526, PNUTS, [RH, Score=87.4, Expect=4e-17]} {Smed: dd_Smed_v6_3726_0_1, dd_Smed_v6_3726_0_1, [Score=93.2, Expect=2e-19]} {RNA1509_35861, RNA1509_3759, RNA1509_41300} {RNA1310_6625, RNA1509_35861, RNA1509_41300} {RNA1509_35861, RNA1509_41300, RNA815_5489}
39. MligTC455_28108 147 3.07 Mlig455_049966, Mlig455_051247

Neo: -

Age: -

0.955 - - - - 0.955 -

Mlig455_049966 {REF} {Length: 1643} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_14078} {RNA815_15623}

Mlig455_051247 {REF} {Length: 862} {NoTransDecoderORF} {RNA1509_57004} {RNA1310_15891} {RNA815_15623}
40. MligTC455_28517 169 3.52 Mlig455_032503

Neo: -

Age: -

0.954 - - - - 0.954 - Mlig455_032503 {REF} {Length: 728} {NoTransDecoderORF} {RNA1310_54604.1} {RNA815_39231}
41. MligTC455_32737 100 2.08 Mlig455_024781, Mlig455_053522

Neo: -

Age: Up-Down-Down

NYNRIN 0.954 - - - - 0.954 -

Mlig455_024781 {REF} {Length: 6075} {Pfam: Integrase core domain [PF00665.28, score=47.6]; Integrase core domain [PF13683.8, score=22.1]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=53.5, Expect=1e-06]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=50.1, Expect=9e-06]} {Smed: dd_Smed_v6_94688_0_1, dd_Smed_v6_94688_0_1, [Score=59.3, Expect=5e-11]} {RNA1509_9393} {RNA1310_740.1} {RNA815_163.1}

Mlig455_053522 {REF} {Length: 941} {Pfam: Integrase core domain [PF00665.28, score=47.7]} {RNA1310_30681} {RNA815_55649}
42. MligTC455_10701 47 0.97 Mlig455_011740

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_011740 {REF} {Length: 4438} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=102.5]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=97.1]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=73.4]; Integrase zinc binding domain [PF17921.3, score=57.0]; Integrase core domain [PF00665.28, score=50.1]; gag-polyprotein putative aspartyl protease [PF13975.8, score=33.8]; Aspartyl protease [PF13650.8, score=25.7]; Retroviral aspartyl protease [PF00077.22, score=20.4]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=271, Expect=3e-75]} {RNA1509_54157} {RNA1310_5940.1} {RNA815_7551.1}
43. MligTC455_49513 233 4.85 Mlig455_022846

Neo: -

Age: -

AGBL2 0.953 - - - - 0.953 - Mlig455_022846 {REF} {Length: 5485} {Pfam: Cytosolic carboxypeptidase N-terminal domain [PF18027.3, score=73.4]; Zinc carboxypeptidase [PF00246.26, score=69.4]} {Human: ENSG00000285501, AGBL2, ATP/GTP binding protein like 2, [RH, Score=598, Expect=0.0]; ENSG00000165923, AGBL2, ATP/GTP binding protein like 2, [RH, Score=598, Expect=0.0]; ENSG00000146856, AGBL3, ATP/GTP binding protein like 3, [RH, Score=591, Expect=0.0]} {Mouse: ENSMUSG00000038836, Agbl3, ATP/GTP binding protein-like 3, [RH, Score=594, Expect=0.0]; ENSMUSG00000040812, Agbl2, ATP/GTP binding protein-like 2, [RH, Score=593, Expect=0.0]} {Dmel: FBgn0265726, Nna1, Nna1 carboxypeptidase, [RH, Score=581, Expect=0.0]} {Celegans: WBGene00018995, ccpp-1, Cytosolic carboxypeptidase 1, [Score=287, Expect=4e-81]} {Smed: dd_Smed_v6_13450_0_1, dd_Smed_v6_13450_0_1, [RH, Score=624, Expect=0.0]} {RNA1509_10895} {RNA1310_2786.1} {RNA815_1445.1}
44. MligTC455_50996 449 9.36 Mlig455_002019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.319

Region-enriched R2: 1.520/0.04245

TRIM71 0.953 - - - - 0.953 - Mlig455_002019 {REF} {Length: 2281} {Pfam: NHL repeat [PF01436.23, score=74.6]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=79.3, Expect=3e-15]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=76.3, Expect=3e-14]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=79.7, Expect=2e-15]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=76.3, Expect=2e-14]} {Dmel: FBgn0265356, tn, thin, [Score=94.0, Expect=3e-20]} {Celegans: WBGene00003026, lin-41, [Score=80.5, Expect=5e-16]} {Smed: dd_Smed_v6_13659_0_1, dd_Smed_v6_13659_0_1, [RH, Score=102, Expect=2e-24]} {RNA1509_17378} {RNA1310_19512.1, RNA1509_17378} {RNA1509_17378, RNA815_7968}
45. MligTC455_21470 491 10.23 Mlig455_028994

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

KCNMA1 0.952 - - - - 0.952 - Mlig455_028994 {REF} {Length: 4059} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=82.1]; Ion channel [PF07885.18, score=48.7]; Ion transport protein [PF00520.33, score=31.6]; TrkA-N domain [PF02254.20, score=27.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=484, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=482, Expect=5e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=479, Expect=1e-150]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=461, Expect=5e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=490, Expect=3e-155]} {RNA1509_10617} {RNA1310_2480.1} {RNA815_984.1}
46. MligTC455_23041 1502 31.29 Mlig455_043274, Mlig455_043300

Neo: -

Age: -

FOXJ1 0.952 - - - - 0.952 -

Mlig455_043274 {REF} {Length: 3849} {TRANSSPLICED} {RNA1509_6271} {RNA1310_4486.1} {RNA815_9655}

Mlig455_043300 {REF} {Length: 4018} {TRANSSPLICED} {Pfam: Forkhead domain [PF00250.20, score=92.4]; Anti-sigma-K factor rskA [PF10099.11, score=26.3]} {Human: ENSG00000129654, FOXJ1, forkhead box J1, [Score=107, Expect=5e-24]} {Mouse: ENSMUSG00000034227, Foxj1, forkhead box J1, [Score=107, Expect=2e-24]} {Dmel: FBgn0004896, fd59A, forkhead domain 59A, [Score=76.6, Expect=2e-14]} {Celegans: WBGene00006853, unc-130, [Score=83.2, Expect=4e-17]} {Smed: dd_Smed_v6_14635_0_1, dd_Smed_v6_14635_0_1, [Score=106, Expect=2e-24]} {RNA1509_6271} {RNA1310_4486.1, RNA1509_6271} {RNA1509_6271, RNA815_9655}
47. MligTC455_28598 102 2.13 Mlig455_057552

Neo: -

Age: -

0.952 - - - - - 0.952 Mlig455_057552 {REF} {Length: 3851} {TRANSSPLICED} {RNA1509_60109} {RNA1310_21727} {RNA815_11299}
48. MligTC455_32519 147 3.06 Mlig455_017549

Neo: -

Age: logFC(26M/2M)=-0.495

NWD2 0.952 - - - - 0.952 - Mlig455_017549 {REF} {Length: 6334} {Pfam: Domain of unknown function (DUF4062) [PF13271.8, score=40.6]; AAA ATPase domain [PF13191.8, score=38.4]; NACHT domain [PF05729.14, score=34.5]; AAA domain [PF13481.8, score=20.7]; ATPase domain predominantly from Archaea [PF01637.20, score=20.2]} {Human: ENSG00000174145, NWD2, NACHT and WD repeat domain containing 2, [Score=347, Expect=8e-99]} {Mouse: ENSMUSG00000090061, Nwd2, NACHT and WD repeat domain containing 2, [Score=340, Expect=1e-96]} {Dmel: FBgn0038397, CG10185, [Score=472, Expect=9e-143]} {Celegans: WBGene00020254, T05C3.2, [Score=527, Expect=1e-162]} {Smed: dd_Smed_v6_11085_0_1, dd_Smed_v6_11085_0_1, [Score=380, Expect=2e-110]} {RNA1509_23488} {RNA1310_497.1} {RNA815_237}
49. MligTC455_46689 295 6.15 Mlig455_064397

Neo: -

Age: -

0.952 - - - - 0.952 - Mlig455_064397 {REF} {Length: 4052} {Pfam: MspA [PF09203.13, score=32.6]} {RNA1509_25060} {RNA1310_2880} {RNA815_15411}
50. MligTC455_43366 86 1.79 Mlig455_055680

Neo: -

Age: logFC(26M/2M)=1.002

TNN 0.951 - - - - 0.951 - Mlig455_055680 {REF} {Length: 2991} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=110.9]} {Human: ENSG00000120332, TNN, tenascin N, [Score=97.4, Expect=4e-22]; ENSG00000166482, MFAP4, microfibril associated protein 4, [Score=93.2, Expect=1e-21]} {Mouse: ENSMUSG00000026725, Tnn, tenascin N, [Score=95.9, Expect=1e-21]; ENSMUSG00000033327, Tnxb, tenascin XB, [Score=92.0, Expect=2e-20]} {Dmel: FBgn0003326, sca, scabrous, [Score=82.4, Expect=2e-17]} {Celegans: WBGene00020516, T15B7.1, [Score=52.4, Expect=1e-07]} {Smed: dd_Smed_v6_74244_0_1, dd_Smed_v6_74244_0_1, [Score=43.5, Expect=1e-05]} {RNA1509_25852} {RNA1310_16471.3} {RNA815_7229.1}
51. MligTC455_20027 1159 24.14 Mlig455_007217, Mlig455_007451

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.831

GCLM 0.95 - - - - 0.950 -

Mlig455_007217 {REF} {Length: 2261} {Human: ENSG00000023909, GCLM, glutamate-cysteine ligase modifier subunit, [RH, Score=120, Expect=7e-32]} {Mouse: ENSMUSG00000028124, Gclm, glutamate-cysteine ligase, modifier subunit, [RH, Score=120, Expect=3e-32]} {Dmel: FBgn0046114, Gclm, Glutamate-cysteine ligase modifier subunit, [Score=78.6, Expect=9e-17]} {Celegans: WBGene00017084, E01A2.1, [RH, Score=78.6, Expect=8e-17]} {Smed: dd_Smed_v6_487_0_1, dd_Smed_v6_487_0_1, [Score=107, Expect=9e-28]} {RNA1509_2089} {RNA1310_10444.1} {RNA815_4215}

Mlig455_007451 {REF} {Length: 2259} {Human: ENSG00000023909, GCLM, glutamate-cysteine ligase modifier subunit, [RH, Score=120, Expect=7e-32]} {Mouse: ENSMUSG00000028124, Gclm, glutamate-cysteine ligase, modifier subunit, [RH, Score=120, Expect=3e-32]} {Dmel: FBgn0046114, Gclm, Glutamate-cysteine ligase modifier subunit, [Score=78.6, Expect=9e-17]} {Celegans: WBGene00017084, E01A2.1, [RH, Score=78.6, Expect=8e-17]} {Smed: dd_Smed_v6_487_0_1, dd_Smed_v6_487_0_1, [Score=107, Expect=9e-28]} {RNA1509_2089} {RNA1310_10444.1} {RNA815_4215}
52. MligTC455_22184 57 1.18 Mlig455_011505

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_011505 {REF} {Length: 715} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=39.4]} {RNA1509_13072} {RNA1310_4523} {RNA815_50872}
53. MligTC455_37523 15 0.31 Mlig455_036094

Neo: -

Age: -

0.95 - - - - 0.950 - Mlig455_036094 {REF} {Length: 1208} {NoTransDecoderORF} {RNA1509_56806} {RNA1310_91623} {RNA815_56086}
54. MligTC455_51393 389 8.1 Mlig455_016576, Mlig455_035611

Neo: -

Age: Up-Down-Down

POFUT2 0.95 - - - - 0.950 -

Mlig455_016576 {REF} {Length: 5592} {Pfam: GDP-fucose protein O-fucosyltransferase [PF10250.11, score=122.0]} {Human: ENSG00000186866, POFUT2, protein O-fucosyltransferase 2, [Score=245, Expect=3e-77]} {Mouse: ENSMUSG00000020260, Pofut2, protein O-fucosyltransferase 2, [Score=248, Expect=1e-78]} {Dmel: FBgn0027791, O-fut2, O-fucosyltransferase 2, [Score=186, Expect=3e-54]} {Celegans: WBGene00010757, pad-2, GDP-fucose protein O-fucosyltransferase 2, [Score=215, Expect=5e-66]} {Smed: dd_Smed_v6_9239_0_1, dd_Smed_v6_9239_0_1, [Score=198, Expect=1e-59]} {RNA1509_19497} {RNA1310_18628.1} {RNA815_10021}

Mlig455_035611 {REF} {Length: 4243} {Pfam: GDP-fucose protein O-fucosyltransferase [PF10250.11, score=87.6]} {Human: ENSG00000186866, POFUT2, protein O-fucosyltransferase 2, [Score=175, Expect=5e-51]} {Mouse: ENSMUSG00000020260, Pofut2, protein O-fucosyltransferase 2, [Score=176, Expect=1e-51]} {Dmel: FBgn0027791, O-fut2, O-fucosyltransferase 2, [Score=108, Expect=3e-26]} {Celegans: WBGene00010757, pad-2, GDP-fucose protein O-fucosyltransferase 2, [Score=147, Expect=4e-41]} {Smed: dd_Smed_v6_9239_0_1, dd_Smed_v6_9239_0_1, [Score=113, Expect=2e-28]} {RNA1509_19497} {RNA1310_18628.1} {RNA815_10021}

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