Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_49573 | 617 | 12.86 | Mlig455_022814 | Neo: - Age: - |
CSK | Mlig455_022814 {REF} {Length: 4126} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.6]; Protein kinase domain [PF00069.27, score=122.4]; Transmembrane Fragile-X-F protein [PF10269.11, score=115.8]; SH2 domain [PF00017.26, score=56.9]} {Human: ENSG00000103653, CSK, C-terminal Src kinase, [RH, Score=342, Expect=1e-108]} {Mouse: ENSMUSG00000032312, Csk, c-src tyrosine kinase, [RH, Score=342, Expect=4e-109]} {Dmel: FBgn0262081, Csk, C-terminal Src kinase, [Score=308, Expect=6e-93]} {Celegans: WBGene00000812, csk-1, Tyrosine-protein kinase csk-1, [Score=278, Expect=8e-84]} {Smed: dd_Smed_v6_6039_0_1, dd_Smed_v6_6039_0_1, [Score=289, Expect=2e-88]} {RNA1509_21196} {RNA1310_5299} {RNA815_7127.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | 0.375 | 3.926 | 0.73476 | 1.00000 | |
RegionR2 | -0.482 | 3.926 | 0.36169 | 0.75655 | |
RegionR3 | -0.396 | 3.926 | 0.38497 | 0.91657 | |
RegionR4 | 0.48 | 3.926 | 0.34801 | 0.66917 | |
RegionR5 | -0.309 | 3.926 | 0.48112 | 0.84473 | |
RegionR6 | -0.093 | 3.926 | 0.83733 | 1.00000 | |
RegionR7 | 0.298 | 3.926 | 0.57816 | 1.00000 | |
RegionR8 | 0.127 | 3.926 | 0.85632 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -7.823 | 3.926 | 0.04148 | 0.67581 | |
RegenerationR2 | -0.332 | 3.926 | 0.50435 | 0.87294 | |
RegenerationR3 | -0.129 | 3.926 | 0.80455 | 0.98360 | |
RegenerationR4 | -0.399 | 3.926 | 0.44326 | 0.83876 | |
RegenerationR5 | 0.228 | 3.926 | 0.64612 | 0.93053 | |
RegenerationR6 | -0.087 | 3.926 | 0.86849 | 1.00000 | |
RegenerationBL | -0.923 | 3.926 | 0.12658 | 0.42279 | |
RegenerationTP | 0.195 | 3.926 | 0.74632 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_49573 | 617 | 12.86 | Mlig455_022814 | Neo: - Age: - |
CSK | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_022814 {REF} {Length: 4126} {TRANSSPLICED} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=259.6]; Protein kinase domain [PF00069.27, score=122.4]; Transmembrane Fragile-X-F protein [PF10269.11, score=115.8]; SH2 domain [PF00017.26, score=56.9]} {Human: ENSG00000103653, CSK, C-terminal Src kinase, [RH, Score=342, Expect=1e-108]} {Mouse: ENSMUSG00000032312, Csk, c-src tyrosine kinase, [RH, Score=342, Expect=4e-109]} {Dmel: FBgn0262081, Csk, C-terminal Src kinase, [Score=308, Expect=6e-93]} {Celegans: WBGene00000812, csk-1, Tyrosine-protein kinase csk-1, [Score=278, Expect=8e-84]} {Smed: dd_Smed_v6_6039_0_1, dd_Smed_v6_6039_0_1, [Score=289, Expect=2e-88]} {RNA1509_21196} {RNA1310_5299} {RNA815_7127.1} |
2. | MligTC455_34887 | 559 | 11.64 | Mlig455_054994 | Neo: - Age: - |
PROM1 | 2.624 | 0.919 | - | - | 0.731 | - | 0.974 | Mlig455_054994 {REF} {Length: 5116} {TRANSSPLICED} {Pfam: Prominin [PF05478.13, score=237.2]; Predicted membrane protein (DUF2207) [PF09972.11, score=18.8]} {Human: ENSG00000007062, PROM1, prominin 1, [Score=103, Expect=6e-22]} {Mouse: ENSMUSG00000029086, Prom1, prominin 1, [RH, Score=142, Expect=3e-34]} {Smed: dd_Smed_v6_1386_0_1, dd_Smed_v6_1386_0_1, [RH, Score=156, Expect=2e-39]} {RNA1509_10333, RNA1509_36111, RNA1509_47961, RNA1509_57078} {RNA1310_3366.1, RNA1509_36111, RNA1509_47961, RNA1509_57078} {RNA1509_36111, RNA1509_47961, RNA1509_57078, RNA815_6629} |
3. | MligTC455_17681 | 333 | 6.94 | Mlig455_023232 | Neo: - Age: - |
TNS1 | 2.538 | - | - | - | 0.881 | 0.702 | 0.955 | Mlig455_023232 {REF} {Length: 2927} {Pfam: SH2 domain [PF00017.26, score=42.4]} {Human: ENSG00000079308, TNS1, tensin 1, [Score=152, Expect=1e-40]; ENSG00000136205, TNS3, tensin 3, [Score=151, Expect=3e-40]; ENSG00000111077, TNS2, tensin 2, [Score=150, Expect=6e-40]} {Mouse: ENSMUSG00000055322, Tns1, tensin 1, [Score=152, Expect=6e-41]; ENSMUSG00000020422, Tns3, tensin 3, [Score=150, Expect=5e-40]; ENSMUSG00000037003, Tns2, tensin 2, [Score=147, Expect=5e-39]} {Dmel: FBgn0000244, by, blistery, [Score=143, Expect=5e-38]} {Celegans: WBGene00006508, tns-1, TeNSin homolog, [Score=136, Expect=8e-38]} {Smed: dd_Smed_v6_4494_0_2, dd_Smed_v6_4494_0_2, [Score=140, Expect=3e-37]} {RNA1509_26639} {RNA1310_9819.1, RNA1509_26639} {RNA1509_26639, RNA815_6016.1} |
4. | MligTC455_20032 | 423 | 8.81 | Mlig455_017713 | Neo: - Age: - |
C16orf89 | 1.773 | 0.954 | - | - | 0.819 | - | - | Mlig455_017713 {REF} {Length: 1385} {Pfam: Domain of unknown function (DUF4735) [PF15882.7, score=96.6]} {Human: ENSG00000153446, C16orf89, chromosome 16 open reading frame 89, [Score=68.2, Expect=4e-12]} {Mouse: ENSMUSG00000051669, AU021092, expressed sequence AU021092, [Score=73.6, Expect=5e-14]} {Dmel: FBgn0034069, CG8401, [Score=48.1, Expect=5e-06]} {Smed: dd_Smed_v6_21285_0_1, dd_Smed_v6_21285_0_1, [Score=69.3, Expect=4e-13]} {RNA1310_35036.1} {RNA815_23082} |
5. | MligTC455_45335 | 1483 | 30.89 | Mlig455_048638, Mlig455_068862 | Neo: - Age: Up-Down-Up |
D2HGDH | 1.725 | - | - | - | 0.759 | 0.966 | - | Mlig455_048638 {REF} {Length: 2059} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=137.0]; FAD binding domain [PF01565.25, score=126.8]} {Human: ENSG00000180902, D2HGDH, D-2-hydroxyglutarate dehydrogenase, [Score=405, Expect=4e-136]} {Mouse: ENSMUSG00000073609, D2hgdh, D-2-hydroxyglutarate dehydrogenase, [Score=411, Expect=3e-138]} {Dmel: FBgn0023507, D2hgdh, D-2-hydroxyglutaric acid dehydrogenase, [Score=371, Expect=1e-122]} {Celegans: WBGene00010055, F54D5.12, [Score=318, Expect=9e-103]} {Smed: dd_Smed_v6_6440_0_1, dd_Smed_v6_6440_0_1, [Score=413, Expect=1e-139]} {RNA1509_50905} {RNA1310_17895.1} {RNA815_10343.1} Mlig455_068862 {REF} {Length: 1918} {TRANSSPLICED} {Pfam: FAD linked oxidases, C-terminal domain [PF02913.21, score=136.4]; FAD binding domain [PF01565.25, score=126.8]} {Human: ENSG00000180902, D2HGDH, D-2-hydroxyglutarate dehydrogenase, [Score=406, Expect=3e-136]} {Mouse: ENSMUSG00000073609, D2hgdh, D-2-hydroxyglutarate dehydrogenase, [Score=411, Expect=3e-138]} {Dmel: FBgn0023507, D2hgdh, D-2-hydroxyglutaric acid dehydrogenase, [Score=370, Expect=1e-122]} {Celegans: WBGene00010055, F54D5.12, [Score=318, Expect=8e-103]} {Smed: dd_Smed_v6_6440_0_1, dd_Smed_v6_6440_0_1, [Score=413, Expect=1e-139]} {RNA1509_50905} {RNA1310_17895.1} {RNA815_10343.1} |
6. | MligTC455_24804 | 9938 | 207.05 | Mlig455_016852 | Neo: - Age: Down-Up-Down Region-enriched R7: 1.271/0.00174 Regeneration-downregulated BL: -2.176 Regeneration-depleted BL: -2.176 |
1.715 | - | - | 0.758 | - | - | 0.957 | Mlig455_016852 {REF} {Length: 655} {Pfam: Thymosin beta-4 family [PF01290.22, score=72.6]} {Dmel: FBgn0026084, cib, ciboulot, [Score=49.7, Expect=2e-08]} {Celegans: WBGene00006649, tth-1, Thymosin beta, [Score=46.2, Expect=4e-07]} {Smed: dd_Smed_v6_12_0_1, dd_Smed_v6_12_0_1, [RH, Score=71.6, Expect=1e-17]} {RNA1509_43581} {RNA1310_57754.2} {RNA815_27242} | |
7. | MligTC455_45987 | 1592 | 33.17 | Mlig455_024379, Mlig455_024495 | Neo: - Age: Up-Down-Down, logFC(26M/2M)=-0.664 Region-specific R8: 3.405 Region-enriched R8: 3.716/0.00000 Regeneration-depleted BL: -2.612 |
PKDREJ | 1.683 | - | - | - | 0.724 | - | 0.959 | Mlig455_024379 {REF} {Length: 9101} {Pfam: PKD domain [PF18911.2, score=34.9]; PKD domain [PF00801.22, score=21.5]} {RNA1509_1257} {RNA1310_126.1} {RNA815_58} Mlig455_024495 {REF} {Length: 8484} {Pfam: Polycystin cation channel [PF08016.14, score=333.9]; PLAT/LH2 domain [PF01477.25, score=69.5]; PKD domain [PF18911.2, score=32.8]; Ion transport protein [PF00520.33, score=31.6]; PKD domain [PF00801.22, score=19.8]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [RH, Score=346, Expect=8e-95]} {Mouse: ENSMUSG00000052496, Pkdrej, polycystin (PKD) family receptor for egg jelly, [RH, Score=327, Expect=4e-89]; ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [RH, Score=319, Expect=7e-87]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=167, Expect=3e-41]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=198, Expect=3e-52]} {Smed: dd_Smed_v6_10962_0_1, dd_Smed_v6_10962_0_1, [Score=592, Expect=9e-172]} {RNA1509_1257} {RNA1310_126.1} {RNA815_58} |
8. | MligTC455_41802 | 231 | 4.81 | Mlig455_028872 | Neo: - Age: logFC(26M/2M)=0.427 |
0.974 | - | - | - | - | - | 0.974 | Mlig455_028872 {REF} {Length: 1053} {NoTransDecoderORF} {RNA1509_33188, RNA1509_48405} {RNA1310_33818, RNA1509_33188, RNA1509_48405} {RNA1509_33188, RNA1509_48405, RNA815_24317} | |
9. | MligTC455_24805 | 4322 | 90.04 | Mlig455_065919 | Neo: - Age: Down-Up-Up, logFC(26M/2M)=1.454 Region-enriched R7: 1.214/0.00538 Regeneration-downregulated BL: -1.666 Regeneration-depleted BL: -1.666 |
0.968 | - | - | - | - | - | 0.968 | Mlig455_065919 {REF} {Length: 723} {Pfam: Thymosin beta-4 family [PF01290.22, score=72.0]} {Dmel: FBgn0026084, cib, ciboulot, [Score=49.3, Expect=5e-08]} {Celegans: WBGene00006649, tth-1, Thymosin beta, [Score=46.6, Expect=5e-07]} {Smed: dd_Smed_v6_12_0_1, dd_Smed_v6_12_0_1, [RH, Score=72.0, Expect=1e-17]} {RNA1509_1534} {RNA1310_57754.2} {RNA815_27242} | |
10. | MligTC455_21850 | 132 | 2.75 | Mlig455_068061 | Neo: - Age: - |
0.964 | 0.964 | - | - | - | - | - | Mlig455_068061 {REF} {Length: 3321} {RNA1509_60168} {RNA1310_96606} {RNA815_23281} | |
11. | MligTC455_23402 | 1537 | 32.03 | Mlig455_045932 | Neo: - Age: - |
DRG2 | 0.961 | - | - | - | - | 0.961 | - | Mlig455_045932 {REF} {Length: 1695} {TRANSSPLICED} {Pfam: C-terminal region of MMR_HSR1 domain [PF16897.7, score=145.3]; 50S ribosome-binding GTPase [PF01926.25, score=75.6]; TGS domain [PF02824.23, score=67.1]; Ferrous iron transport protein B [PF02421.20, score=47.8]} {Human: ENSG00000108591, DRG2, developmentally regulated GTP binding protein 2, [RH, Score=591, Expect=0.0]} {Mouse: ENSMUSG00000020537, Drg2, developmentally regulated GTP binding protein 2, [RH, Score=590, Expect=0.0]} {Dmel: FBgn0038723, CG6195, [RH, Score=574, Expect=0.0]} {Celegans: WBGene00015346, C02F5.3, Uncharacterized GTP-binding protein C02F5.3, [RH, Score=573, Expect=0.0]} {Smed: dd_Smed_v6_4208_0_1, dd_Smed_v6_4208_0_1, [RH, Score=573, Expect=0.0]} {RNA1509_3521} {RNA1310_3565, RNA1509_3521} {RNA1509_3521, RNA815_6941} |
12. | MligTC455_27320 | 692 | 14.41 | Mlig455_027276, Mlig455_027289, Mlig455_067498 | Neo: - Age: logFC(26M/2M)=0.333 |
0.959 | - | - | - | - | - | 0.959 | Mlig455_027276 {REF} {Length: 2566} {RNA1509_30201} {RNA1310_15445.1} {RNA815_9511.1} Mlig455_027289 {REF} {Length: 4607} {Pfam: Cupin-like domain [PF13621.8, score=88.8]; Cupin superfamily protein [PF08007.14, score=23.0]} {Dmel: FBgn0035166, CG13902, [Score=62.8, Expect=5e-10]} {Smed: dd_Smed_v6_14490_0_1, dd_Smed_v6_14490_0_1, [Score=318, Expect=2e-101]} {RNA1509_30201} {RNA1310_15445.1} {RNA815_9511.1} Mlig455_067498 {REF} {Length: 4098} {Pfam: Cupin-like domain [PF13621.8, score=90.5]; Cupin superfamily protein [PF08007.14, score=22.8]} {Mouse: ENSMUSG00000030752, Kdm8, lysine (K)-specific demethylase 8, [Score=58.9, Expect=1e-08]} {Dmel: FBgn0035166, CG13902, [Score=60.1, Expect=3e-09]} {Celegans: WBGene00007387, jmjd-5, JuMonJi (Transcription factor) Domain protein, [Score=53.9, Expect=3e-07]} {Smed: dd_Smed_v6_14490_0_1, dd_Smed_v6_14490_0_1, [RH, Score=355, Expect=1e-115]} {RNA1509_20375} {RNA1310_22474} {RNA815_8659} |
|
13. | MligTC455_26694 | 1228 | 25.58 | Mlig455_028310 | Neo: - Age: - |
RUVBL2 | 0.957 | - | - | - | - | 0.957 | - | Mlig455_028310 {REF} {Length: 2045} {Pfam: TIP49 P-loop domain [PF06068.15, score=542.3]; TIP49 AAA-lid domain [PF17856.3, score=98.4]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=33.7]; AAA ATPase domain [PF13191.8, score=28.3]; DnaB-like helicase C terminal domain [PF03796.17, score=26.9]; AAA domain (dynein-related subfamily) [PF07728.16, score=25.8]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=25.2]; AAA domain [PF13245.8, score=24.4]; AAA domain [PF13401.8, score=22.9]; Sigma-54 interaction domain [PF00158.28, score=21.9]; Magnesium chelatase, subunit ChlI [PF01078.23, score=21.0]; AAA domain [PF13481.8, score=20.9]} {Human: ENSG00000183207, RUVBL2, RuvB like AAA ATPase 2, [RH, Score=808, Expect=0.0]} {Mouse: ENSMUSG00000003868, Ruvbl2, RuvB-like protein 2, [RH, Score=806, Expect=0.0]} {Dmel: FBgn0040075, rept, reptin, [RH, Score=748, Expect=0.0]} {Celegans: WBGene00020687, ruvb-2, RuvB-like 2, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_2547_0_1, dd_Smed_v6_2547_0_1, [RH, Score=740, Expect=0.0]} {RNA1509_12047} {RNA1310_13037} {RNA815_5004.1} |
14. | MligTC455_33612 | 217 | 4.51 | Mlig455_017362 | Neo: - Age: logFC(26M/2M)=0.818 |
ASAH2 | 0.957 | - | - | - | - | 0.957 | - | Mlig455_017362 {REF} {Length: 6769} {Pfam: Neutral/alkaline non-lysosomal ceramidase, N-terminal [PF04734.15, score=704.1]; Neutral/alkaline non-lysosomal ceramidase, C-terminal [PF17048.7, score=119.9]; Major Facilitator Superfamily [PF07690.18, score=92.8]} {Human: ENSG00000188611, ASAH2, N-acylsphingosine amidohydrolase 2, [RH, Score=602, Expect=0.0]} {Mouse: ENSMUSG00000024887, Asah2, N-acylsphingosine amidohydrolase 2, [RH, Score=594, Expect=0.0]} {Dmel: FBgn0039774, CDase, Ceramidase, [RH, Score=568, Expect=0.0]} {Celegans: WBGene00011719, T11G6.4, [Score=122, Expect=7e-29]} {Smed: dd_Smed_v6_1726_0_1, dd_Smed_v6_1726_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_25115} {RNA1310_8395.1} {RNA815_2759} |
15. | MligTC455_38747 | 478 | 9.95 | Mlig455_067326 | Neo: - Age: - Region-enriched R6: 2.933/0.00107 |
0.957 | - | - | - | - | - | 0.957 | Mlig455_067326 {REF} {Length: 2531} {Pfam: Ras association (RalGDS/AF-6) domain [PF00788.25, score=25.1]} {Smed: dd_Smed_v6_11758_0_1, dd_Smed_v6_11758_0_1, [RH, Score=53.1, Expect=1e-08]} {RNA1509_16620} {RNA1310_13139.1} {RNA815_14453} | |
16. | MligTC455_20674 | 2347 | 48.9 | Mlig455_011615 | Neo: - Age: - Regeneration-downregulated BL: -1.557 Regeneration-depleted BL: -1.557 |
0.955 | - | - | - | - | - | 0.955 | Mlig455_011615 {REF} {Length: 3475} {TRANSSPLICED} {RNA1509_1877, RNA1509_34283} {RNA1310_15601, RNA1509_34283} {RNA1509_34283, RNA815_2760} | |
17. | MligTC455_37645 | 245 | 5.11 | Mlig455_009094 | Neo: - |
0.954 | - | - | - | - | - | 0.954 | Mlig455_009094 {REF} {Length: 1970} {RNA1509_21906} {RNA1310_21443.1} {RNA815_8970.1} | |
18. | MligTC455_21697 | 2521 | 52.53 | Mlig455_041412, Mlig455_041449 | Neo: - Age: - |
0.95 | - | - | - | - | 0.950 | - | Mlig455_041412 {REF} {Length: 7796} {TRANSSPLICED} {RNA1509_3457, RNA1509_36712, RNA1509_55043, RNA1509_8934} {RNA1310_1968.1, RNA1509_3457, RNA1509_36712, RNA1509_55043} {RNA1509_3457, RNA1509_36712, RNA1509_55043, RNA815_2193.1} Mlig455_041449 {REF} {Length: 7329} {TRANSSPLICED} {RNA1509_8934} {RNA1310_1968.1, RNA1509_8934} {RNA1509_8934, RNA815_2193.1} |