Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_51337 | 178 | 3.71 | Mlig455_037475 | Neo: - Age: - |
IARS2 | Mlig455_037475 {REF} {Length: 3731} {TRANSSPLICED} {Pfam: tRNA synthetases class I (I, L, M and V) [PF00133.24, score=453.9]; tRNA synthetases class I (M) [PF09334.13, score=66.0]; Anticodon-binding domain of tRNA ligase [PF08264.15, score=47.6]; Leucyl-tRNA synthetase, Domain 2 [PF13603.8, score=24.7]} {Human: ENSG00000067704, IARS2, isoleucyl-tRNA synthetase 2, mitochondrial, [RH, Score=553, Expect=0.0]} {Mouse: ENSMUSG00000026618, Iars2, isoleucine-tRNA synthetase 2, mitochondrial, [RH, Score=556, Expect=0.0]} {Dmel: FBgn0036569, IleRS-m, Isoleucyl-tRNA synthetase, mitochondrial, [RH, Score=510, Expect=3e-165]} {Celegans: WBGene00002153, iars-2, Isoleucyl Amino-acyl tRNA Synthetase, [RH, Score=462, Expect=4e-147]} {Smed: dd_Smed_v6_7613_0_1, dd_Smed_v6_7613_0_1, [RH, Score=529, Expect=1e-172]} {RNA1509_14916} {RNA1310_3724, RNA1509_14916} {RNA1509_14916, RNA815_38112} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -5.564 | 2.579 | 0.21676 | 0.85814 | |
RegionR2 | 0.815 | 2.579 | 0.45297 | 0.84032 | |
RegionR3 | 1.209 | 2.579 | 0.13681 | 0.63272 | |
RegionR4 | 0.618 | 2.579 | 0.54894 | 0.87007 | |
RegionR5 | 1.263 | 2.579 | 0.08481 | 0.27258 | |
RegionR6 | 1.273 | 2.579 | 0.12940 | 0.65016 | |
RegionR7 | 0.131 | 2.579 | 0.81627 | 1.00000 | |
RegionR8 | 0.255 | 2.579 | 0.77906 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 1.182 | 2.579 | 0.99982 | 1.00000 | |
RegenerationR2 | -0.286 | 2.579 | 0.65198 | 0.93716 | |
RegenerationR3 | -0.204 | 2.579 | 0.75390 | 0.96587 | |
RegenerationR4 | -0.565 | 2.579 | 0.42668 | 0.82900 | |
RegenerationR5 | -0.513 | 2.579 | 0.37131 | 0.78103 | |
RegenerationR6 | 0.587 | 2.579 | 0.33195 | 0.67803 | |
RegenerationBL | 1.555 | 2.579 | 0.05759 | 0.27826 | |
RegenerationTP | 0.184 | 2.579 | 0.86896 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_51337 | 178 | 3.71 | Mlig455_037475 | Neo: - Age: - |
IARS2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_037475 {REF} {Length: 3731} {TRANSSPLICED} {Pfam: tRNA synthetases class I (I, L, M and V) [PF00133.24, score=453.9]; tRNA synthetases class I (M) [PF09334.13, score=66.0]; Anticodon-binding domain of tRNA ligase [PF08264.15, score=47.6]; Leucyl-tRNA synthetase, Domain 2 [PF13603.8, score=24.7]} {Human: ENSG00000067704, IARS2, isoleucyl-tRNA synthetase 2, mitochondrial, [RH, Score=553, Expect=0.0]} {Mouse: ENSMUSG00000026618, Iars2, isoleucine-tRNA synthetase 2, mitochondrial, [RH, Score=556, Expect=0.0]} {Dmel: FBgn0036569, IleRS-m, Isoleucyl-tRNA synthetase, mitochondrial, [RH, Score=510, Expect=3e-165]} {Celegans: WBGene00002153, iars-2, Isoleucyl Amino-acyl tRNA Synthetase, [RH, Score=462, Expect=4e-147]} {Smed: dd_Smed_v6_7613_0_1, dd_Smed_v6_7613_0_1, [RH, Score=529, Expect=1e-172]} {RNA1509_14916} {RNA1310_3724, RNA1509_14916} {RNA1509_14916, RNA815_38112} |
2. | MligTC455_52377 | 541 | 11.26 | Mlig455_069932, Mlig455_069939 | Neo: Int S/G2/M Age: - |
1.867 | - | - | - | 0.913 | - | 0.954 | Mlig455_069932 {REF} {Length: 1671} {TRANSSPLICED} {RNA1509_41731} {RNA1310_28989} {RNA815_37154} Mlig455_069939 {REF} {Length: 1669} {TRANSSPLICED} {RNA1509_41731} {RNA1310_28989, RNA1509_41731} {RNA1509_41731, RNA815_37154} |
|
3. | MligTC455_42676 | 549 | 11.43 | Mlig455_033312 | Neo: Int S/G2/M Age: - |
TMEM18 | 1.843 | - | - | - | - | 0.957 | 0.886 | Mlig455_033312 {REF} {Length: 1549} {TRANSSPLICED} {Pfam: Transmembrane protein 18 [PF14770.8, score=93.2]} {Human: ENSG00000151353, TMEM18, transmembrane protein 18, [RH, Score=69.7, Expect=2e-15]} {Mouse: ENSMUSG00000043061, Tmem18, transmembrane protein 18, [RH, Score=45.1, Expect=2e-06]} {RNA1509_34378} {RNA1310_53606, RNA1509_34378} {RNA1509_34378, RNA815_13373.2} |
4. | MligTC455_46945 | 992 | 20.68 | Mlig455_025688 | Neo: Neoblast, stringent Age: Down-Down-Up Region-enriched R6: 3.040/0.00002 Regeneration-upregulated BL: 2.709 Regeneration-enriched BL: 2.709 |
RREB1 | 0.986 | - | - | - | 0.986 | - | - | Mlig455_025688 {REF} {Length: 2364} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=50.3]; C2H2-type zinc finger [PF13894.8, score=45.1]; Zinc-finger double domain [PF13465.8, score=38.0]; Drought induced 19 protein (Di19), zinc-binding [PF05605.14, score=21.3]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=19.1]} {Human: ENSG00000124782, RREB1, ras responsive element binding protein 1, [RH, Score=104, Expect=1e-22]} {Mouse: ENSMUSG00000039087, Rreb1, ras responsive element binding protein 1, [RH, Score=101, Expect=9e-22]} {Dmel: FBgn0003053, peb, pebbled, [Score=95.5, Expect=5e-20]} {Celegans: WBGene00018567, F47E1.3, [Score=64.3, Expect=1e-10]} {Smed: dd_Smed_v6_10103_0_1, dd_Smed_v6_10103_0_1, [RH, Score=122, Expect=9e-30]} {RNA1509_41001, RNA1509_53538} {RNA1310_12985.1, RNA1509_41001, RNA1509_53538} {RNA1509_41001, RNA1509_53538, RNA815_27232} |
5. | MligTC455_12575 | 79 | 1.65 | Mlig455_012353 | Neo: - Age: - |
0.983 | - | - | 0.983 | - | - | - | Mlig455_012353 {REF} {Length: 4480} {Pfam: HEPN domain [PF05168.16, score=36.4]} {RNA1509_38998} {RNA1310_342} {RNA815_1022.1} | |
6. | MligTC455_42999 | 650 | 13.55 | Mlig455_050082 | Neo: - Age: Down-Up-Down, logFC(26M/2M)=-0.377 Regeneration-upregulated BL: 3.339 Regeneration-enriched BL: 3.339 |
0.979 | - | - | - | - | - | 0.979 | Mlig455_050082 {REF} {Length: 2748} {Pfam: Seryl-tRNA synthetase N-terminal domain [PF02403.24, score=26.3]; Snapin/Pallidin [PF14712.8, score=23.3]; Fez1 [PF06818.17, score=21.6]; Crescentin protein [PF19220.2, score=17.7]} {RNA1509_12731} {RNA1310_34600} {RNA815_16012} | |
7. | MligTC455_11736 | 19 | 0.39 | Mlig455_031660 | Neo: - Age: - |
0.971 | - | - | - | 0.971 | - | - | Mlig455_031660 {REF} {Length: 680} {RNA1310_76333} {RNA815_54433} | |
8. | MligTC455_50019 | 248 | 5.17 | Mlig455_050542 | Neo: Int S/G2/M Age: Up-Up-Down |
NSD2 | 0.97 | - | - | - | - | - | 0.970 | Mlig455_050542 {REF} {Length: 4778} {TRANSSPLICED} {Pfam: PWWP domain [PF00855.19, score=113.6]; SET domain [PF00856.30, score=80.1]; AWS domain [PF17907.3, score=47.6]; PHD-finger [PF00628.31, score=38.8]; NSD Cys-His rich domain [PF17982.3, score=32.8]} {Human: ENSG00000109685, NSD2, nuclear receptor binding SET domain protein 2, [RH, Score=691, Expect=0.0]; ENSG00000165671, NSD1, nuclear receptor binding SET domain protein 1, [RH, Score=667, Expect=0.0]; ENSG00000147548, NSD3, nuclear receptor binding SET domain protein 3, [RH, Score=664, Expect=0.0]} {Mouse: ENSMUSG00000057406, Nsd2, nuclear receptor binding SET domain protein 2, [RH, Score=696, Expect=0.0]; ENSMUSG00000021488, Nsd1, nuclear receptor-binding SET-domain protein 1, [RH, Score=674, Expect=0.0]} {Dmel: FBgn0039559, NSD, Nuclear receptor binding SET domain protein, [RH, Score=431, Expect=1e-130]} {Celegans: WBGene00016603, met-1, Histone-lysine N-methyltransferase, [Score=142, Expect=5e-34]} {Smed: dd_Smed_v6_4755_0_1, dd_Smed_v6_4755_0_1, [RH, Score=582, Expect=0.0]} {RNA1509_8385} {RNA1310_4002, RNA1509_8385} {RNA1509_8385, RNA815_849} |
9. | MligTC455_12236 | 60 | 1.26 | Mlig455_048744 | Neo: - Age: - |
0.966 | - | - | - | - | - | 0.966 | Mlig455_048744 {REF} {Length: 785} {NoTransDecoderORF} {RNA1509_30946} {RNA1310_87811} {RNA815_14080} | |
10. | MligTC455_41109 | 212 | 4.42 | Mlig455_044541, Mlig455_068558 | Neo: - Age: Down-Down-Up |
0.965 | - | - | - | - | - | 0.965 | Mlig455_044541 {REF} {Length: 2618} {RNA1509_50994} {RNA1310_14102} {RNA815_21266} Mlig455_068558 {REF} {Length: 2571} {RNA1509_50994} {RNA1310_14102} {RNA815_21266} |
|
11. | MligTC455_47461 | 351 | 7.31 | Mlig455_059023 | Neo: - Age: - |
KLHDC2 | 0.965 | - | - | - | - | - | 0.965 | Mlig455_059023 {REF} {Length: 3259} {TRANSSPLICED} {Pfam: Galactose oxidase, central domain [PF13418.8, score=85.8]; Kelch motif [PF13964.8, score=72.1]; Kelch motif [PF13854.8, score=60.0]; Galactose oxidase, central domain [PF13415.8, score=51.1]; Kelch motif [PF07646.17, score=40.8]; Kelch motif [PF01344.27, score=38.8]} {Human: ENSG00000165516, KLHDC2, kelch domain containing 2, [RH, Score=124, Expect=3e-30]} {Mouse: ENSMUSG00000020978, Klhdc2, kelch domain containing 2, [RH, Score=125, Expect=7e-31]} {Dmel: FBgn0040344, CG3711, [Score=62.0, Expect=1e-09]} {Celegans: WBGene00009978, F53E4.1, [Score=59.3, Expect=4e-09]} {Smed: dd_Smed_v6_9892_0_1, dd_Smed_v6_9892_0_1, [RH, Score=96.7, Expect=2e-21]} {RNA1509_12374, RNA1509_47894} {RNA1310_7705.2, RNA1509_12374, RNA1509_47894} {RNA1509_12374, RNA1509_47894, RNA815_5080} |
12. | MligTC455_22201 | 892 | 18.59 | Mlig455_045089 | Neo: - Age: - Region-enriched R7: 1.426/0.02956 Regeneration-upregulated BL: 1.589 Regeneration-enriched BL: 1.589 |
TLL1 | 0.962 | - | - | - | - | - | 0.962 | Mlig455_045089 {REF} {Length: 3960} {Pfam: CUB domain [PF00431.22, score=500.8]; Astacin (Peptidase family M12A) [PF01400.26, score=226.0]; Coagulation Factor Xa inhibitory site [PF14670.8, score=57.7]; Calcium-binding EGF domain [PF07645.17, score=41.2]; Complement Clr-like EGF-like [PF12662.9, score=32.2]; EGF domain [PF12947.9, score=24.5]; CUB-like domain [PF02408.22, score=24.0]; Human growth factor-like EGF [PF12661.9, score=21.4]; EGF-like domain [PF00008.29, score=20.3]} {Human: ENSG00000038295, TLL1, tolloid like 1, [RH, Score=877, Expect=0.0]; ENSG00000095587, TLL2, tolloid like 2, [RH, Score=876, Expect=0.0]; ENSG00000168487, BMP1, bone morphogenetic protein 1, [RH, Score=865, Expect=0.0]} {Mouse: ENSMUSG00000025013, Tll2, tolloid-like 2, [RH, Score=881, Expect=0.0]; ENSMUSG00000022098, Bmp1, bone morphogenetic protein 1, [RH, Score=867, Expect=0.0]; ENSMUSG00000053626, Tll1, tolloid-like, [RH, Score=863, Expect=0.0]} {Dmel: FBgn0004885, tok, tolkin, [RH, Score=864, Expect=0.0]} {Celegans: WBGene00003555, nas-39, Zinc metalloproteinase nas-39, [RH, Score=716, Expect=0.0]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [RH, Score=888, Expect=0.0]} {RNA1509_7883} {RNA1310_2749, RNA1509_7883} {RNA1509_7883, RNA815_1455} |
13. | MligTC455_28413 | 107 | 2.22 | Mlig455_032935 | Neo: - Age: - |
0.962 | - | - | - | - | - | 0.962 | Mlig455_032935 {REF} {Length: 3941} {RNA1509_15744} {RNA1310_6945.1} {RNA815_14623.1} | |
14. | MligTC455_28968 | 39 | 0.82 | Mlig455_029429 | Neo: - Age: Down-Up-Up Region-enriched R4: 5.079/0.03575 |
0.961 | - | - | 0.961 | - | - | - | Mlig455_029429 {REF} {Length: 1492} {RNA1509_35570} {RNA1310_22735} {RNA815_10186} | |
15. | MligTC455_13151 | 56 | 1.18 | Mlig455_034235 | Neo: - Age: logFC(26M/2M)=0.751 |
KYAT3 | 0.96 | - | - | - | - | - | 0.960 | Mlig455_034235 {REF} {Length: 1387} {Pfam: Aminotransferase class I and II [PF00155.23, score=101.6]} {Human: ENSG00000137944, KYAT3, kynurenine aminotransferase 3, [Score=65.5, Expect=5e-11]} {Mouse: ENSMUSG00000040213, Kyat3, kynurenine aminotransferase 3, [Score=64.3, Expect=8e-11]} {Dmel: FBgn0037955, CG6950, [Score=67.0, Expect=7e-12]} {Celegans: WBGene00010984, nkat-3, Nematode Kynurenine AminoTransferase, [Score=70.5, Expect=5e-13]} {Smed: dd_Smed_v6_3796_0_1, dd_Smed_v6_3796_0_1, [Score=66.6, Expect=5e-12]} {RNA1310_24117} {RNA815_18458} |
16. | MligTC455_36775 | 251 | 5.23 | Mlig455_045520 | Neo: - Age: - Region-enriched R2: 6.301/0.00000 Regeneration-downregulated R2: -3.720 Regeneration-depleted R2: -3.720 |
0.959 | - | - | - | - | - | 0.959 | Mlig455_045520 {REF} {Length: 976} {RNA1509_48740} {RNA1310_54738.1} {RNA815_27047} | |
17. | MligTC455_18219 | 159 | 3.31 | Mlig455_030558 | Neo: - Age: logFC(26M/2M)=0.671 |
0.957 | - | - | - | - | - | 0.957 | Mlig455_030558 {REF} {Length: 1656} {TRANSSPLICED} {RNA1310_40507.1} {RNA815_32588} | |
18. | MligTC455_16863 | 349 | 7.26 | Mlig455_009275 | Neo: - Age: Down-Up-Down |
DYRK1B | 0.955 | - | - | 0.955 | - | - | - | Mlig455_009275 {REF} {Length: 5761} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=162.5]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=82.6]} {Human: ENSG00000281320, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000105204, DYRK1B, dual specificity tyrosine phosphorylation regulated kinase 1B, [Score=479, Expect=9e-163]; ENSG00000157540, DYRK1A, dual specificity tyrosine phosphorylation regulated kinase 1A, [Score=469, Expect=1e-157]} {Mouse: ENSMUSG00000002409, Dyrk1b, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b, [Score=480, Expect=3e-162]; ENSMUSG00000022897, Dyrk1a, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a, [Score=470, Expect=5e-158]} {Dmel: FBgn0259168, mnb, minibrain, [Score=495, Expect=1e-169]} {Celegans: WBGene00003149, mbk-1, Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1, [Score=431, Expect=3e-141]} {Smed: dd_Smed_v6_3773_0_1, dd_Smed_v6_3773_0_1, [Score=425, Expect=3e-136]} {RNA1509_9464} {RNA1310_10341} {RNA815_7238.1} |
19. | MligTC455_39569 | 194 | 4.05 | Mlig455_006055, Mlig455_028715 | Neo: Int S/G2/M Age: - |
ZAN | 0.955 | - | - | - | - | - | 0.955 | Mlig455_006055 {REF} {Length: 1262} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=61.5]} {RNA1310_85984} Mlig455_028715 {REF} {Length: 4529} {Pfam: SH2 domain [PF00017.26, score=22.0]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=60.1, Expect=2e-08]} {RNA1509_15981} {RNA1310_15741} {RNA815_13643} |
20. | MligTC455_38350 | 86 | 1.78 | Mlig455_039927 | Neo: - Age: - |
0.954 | - | - | - | - | - | 0.954 | Mlig455_039927 {REF} {Length: 3262} {RNA1509_17147} {RNA1310_17243} {RNA815_34486} | |
21. | MligTC455_36452 | 280 | 5.84 | Mlig455_035563 | Neo: - Age: Down-Up-Down |
FBXW7 | 0.952 | - | - | - | - | - | 0.952 | Mlig455_035563 {REF} {Length: 4662} {TRANSSPLICED} {Pfam: WD domain, G-beta repeat [PF00400.34, score=132.2]; F-box-like [PF12937.9, score=49.0]; F-box domain [PF00646.35, score=33.3]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=23.3]; Nucleoporin Nup120/160 [PF11715.10, score=22.7]} {Human: ENSG00000109670, FBXW7, F-box and WD repeat domain containing 7, [RH, Score=429, Expect=8e-143]} {Mouse: ENSMUSG00000028086, Fbxw7, F-box and WD-40 domain protein 7, [RH, Score=429, Expect=1e-142]} {Dmel: FBgn0041171, ago, archipelago, [RH, Score=414, Expect=2e-131]} {Celegans: WBGene00004767, sel-10, F-box/WD repeat-containing protein sel-10, [RH, Score=310, Expect=2e-98]} {Smed: dd_Smed_v6_8211_0_1, dd_Smed_v6_8211_0_1, [RH, Score=282, Expect=2e-89]} {RNA1509_19180, RNA1509_36471} {RNA1310_4381, RNA1509_36471} {RNA1509_36471, RNA815_6050} |