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Results for MligTC455_51413

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_51413 414 8.63 Mlig455_025235

Neo: -

Age: logFC(26M/2M)=0.368

CTH Mlig455_025235 {REF} {Length: 1605} {TRANSSPLICED} {Pfam: Cys/Met metabolism PLP-dependent enzyme [PF01053.22, score=442.5]; Methionine gamma-lyase [PF06838.13, score=17.2]} {Human: ENSG00000116761, CTH, cystathionine gamma-lyase, [RH, Score=411, Expect=1e-140]} {Mouse: ENSMUSG00000028179, Cth, cystathionase (cystathionine gamma-lyase), [RH, Score=423, Expect=1e-145]} {Dmel: FBgn0000566, Eip55E, [RH, Score=427, Expect=3e-147]} {Celegans: WBGene00022856, cth-2, Putative cystathionine gamma-lyase 2, [RH, Score=419, Expect=3e-144]} {Smed: dd_Smed_v6_2859_0_1, dd_Smed_v6_2859_0_1, [RH, Score=402, Expect=2e-137]} {RNA1509_28820} {RNA1310_16713} {RNA815_6828.1}

Cumulative graph for MligTC455_51413

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.741 3.529 0.63135 1.00000
RegionR2 0.414 3.529 0.49177 0.87275
RegionR3 0.622 3.529 0.15870 0.67446
RegionR4 0.091 3.529 0.87104 1.00000
RegionR5 0.5 3.529 0.22617 0.53073
RegionR6 0.42 3.529 0.37480 0.95526
RegionR7 0.098 3.529 0.87119 1.00000
RegionR8 -1.405 3.529 0.11852 0.63410

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -4.458 3.529 0.44628 1.00000
RegenerationR2 0.505 3.529 0.27996 0.72374
RegenerationR3 0.557 3.529 0.29181 0.72383
RegenerationR4 0.391 3.529 0.49190 0.86554
RegenerationR5 0.338 3.529 0.47749 0.84580
RegenerationR6 0.508 3.529 0.34834 0.69354
RegenerationBL 1.454 3.529 0.03071 0.19559
RegenerationTP 1.565 3.529 0.03226 0.30145


Genes with expression patterns similar to MligTC455_51413

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_51413 414 8.63 Mlig455_025235

Neo: -

Age: logFC(26M/2M)=0.368

CTH 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_025235 {REF} {Length: 1605} {TRANSSPLICED} {Pfam: Cys/Met metabolism PLP-dependent enzyme [PF01053.22, score=442.5]; Methionine gamma-lyase [PF06838.13, score=17.2]} {Human: ENSG00000116761, CTH, cystathionine gamma-lyase, [RH, Score=411, Expect=1e-140]} {Mouse: ENSMUSG00000028179, Cth, cystathionase (cystathionine gamma-lyase), [RH, Score=423, Expect=1e-145]} {Dmel: FBgn0000566, Eip55E, [RH, Score=427, Expect=3e-147]} {Celegans: WBGene00022856, cth-2, Putative cystathionine gamma-lyase 2, [RH, Score=419, Expect=3e-144]} {Smed: dd_Smed_v6_2859_0_1, dd_Smed_v6_2859_0_1, [RH, Score=402, Expect=2e-137]} {RNA1509_28820} {RNA1310_16713} {RNA815_6828.1}
2. MligTC455_08781 795 16.57 Mlig455_004020, Mlig455_004051, Mlig455_004104

Neo: -

Age: Up-Down-Down

Region-enriched R2: 1.753/0.01741
Region-enriched R5: 1.075/0.03323

UBR5 1.688 - - - 0.952 - 0.736

Mlig455_004020 {REF} {Length: 900} {NoTransDecoderORF} {RNA1509_29921} {RNA1310_12070} {RNA815_9938}

Mlig455_004051 {REF} {Length: 10870} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=204.4]; Poly-adenylate binding protein, unique domain [PF00658.20, score=70.9]} {Human: ENSG00000104517, UBR5, ubiquitin protein ligase E3 component n-recognin 5, [RH, Score=568, Expect=3e-164]} {Mouse: ENSMUSG00000037487, Ubr5, ubiquitin protein ligase E3 component n-recognin 5, [RH, Score=568, Expect=5e-164]} {Dmel: FBgn0002431, hyd, hyperplastic discs, [RH, Score=576, Expect=1e-166]} {Celegans: WBGene00009460, ubr-5, UBR E3 ubiquitin ligase homolog, [RH, Score=250, Expect=3e-66]} {Smed: dd_Smed_v6_7658_0_1, dd_Smed_v6_7658_0_1, [RH, Score=474, Expect=1e-134]} {RNA1509_29921, RNA1509_4055} {RNA1310_350, RNA1509_29921, RNA1509_4055} {RNA1509_29921, RNA1509_4055, RNA815_1156}

Mlig455_004104 {REF} {Length: 10283} {Pfam: HECT-domain (ubiquitin-transferase) [PF00632.27, score=204.2]; E3 ubiquitin ligase EDD [PF11547.10, score=98.2]; Poly-adenylate binding protein, unique domain [PF00658.20, score=70.7]} {Human: ENSG00000104517, UBR5, ubiquitin protein ligase E3 component n-recognin 5, [RH, Score=751, Expect=0.0]} {Mouse: ENSMUSG00000037487, Ubr5, ubiquitin protein ligase E3 component n-recognin 5, [RH, Score=754, Expect=0.0]} {Dmel: FBgn0002431, hyd, hyperplastic discs, [RH, Score=575, Expect=3e-165]} {Celegans: WBGene00009460, ubr-5, UBR E3 ubiquitin ligase homolog, [RH, Score=249, Expect=1e-65]} {Smed: dd_Smed_v6_7658_0_1, dd_Smed_v6_7658_0_1, [RH, Score=473, Expect=1e-133]} {RNA1509_4055, RNA1509_41572, RNA1509_9074} {RNA1310_350, RNA1509_41572, RNA1509_9074} {RNA1509_41572, RNA1509_9074, RNA815_1156}
3. MligTC455_12035 25 0.53 Mlig455_058255, Mlig455_058270

Neo: -

Age: Up-Down-Down

GRIN2A 0.961 - - - - 0.961 -

Mlig455_058255 {REF} {Length: 3970} {Pfam: Ligand-gated ion channel [PF00060.28, score=100.5]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=79.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=71.8]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000183454, GRIN2A, glutamate ionotropic receptor NMDA type subunit 2A, [RH, Score=346, Expect=5e-100]; ENSG00000161509, GRIN2C, glutamate ionotropic receptor NMDA type subunit 2C, [RH, Score=343, Expect=4e-101]; ENSG00000273079, GRIN2B, glutamate ionotropic receptor NMDA type subunit 2B, [RH, Score=338, Expect=6e-96]; ENSG00000105464, GRIN2D, glutamate ionotropic receptor NMDA type subunit 2D, [RH, Score=332, Expect=5e-94]} {Mouse: ENSMUSG00000059003, Grin2a, glutamate receptor, ionotropic, NMDA2A (epsilon 1), [RH, Score=347, Expect=6e-99]; ENSMUSG00000020734, Grin2c, glutamate receptor, ionotropic, NMDA2C (epsilon 3), [RH, Score=341, Expect=5e-98]; ENSMUSG00000030209, Grin2b, glutamate receptor, ionotropic, NMDA2B (epsilon 2), [RH, Score=341, Expect=7e-97]; ENSMUSG00000002771, Grin2d, glutamate receptor, ionotropic, NMDA2D (epsilon 4), [RH, Score=331, Expect=4e-94]} {Dmel: FBgn0053513, Nmdar2, NMDA receptor 2, [RH, Score=532, Expect=2e-169]} {Celegans: WBGene00003775, nmr-2, NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-2, [RH, Score=459, Expect=5e-143]} {Smed: dd_Smed_v6_19886_0_1, dd_Smed_v6_19886_0_1, [RH, Score=872, Expect=0.0]} {RNA1509_56620} {RNA1310_18260} {RNA815_11857}

Mlig455_058270 {REF} {Length: 4037} {Pfam: Ligand-gated ion channel [PF00060.28, score=99.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=79.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=71.9]; Receptor family ligand binding region [PF01094.30, score=21.3]} {Human: ENSG00000183454, GRIN2A, glutamate ionotropic receptor NMDA type subunit 2A, [RH, Score=347, Expect=9e-99]; ENSG00000161509, GRIN2C, glutamate ionotropic receptor NMDA type subunit 2C, [RH, Score=343, Expect=4e-101]; ENSG00000273079, GRIN2B, glutamate ionotropic receptor NMDA type subunit 2B, [RH, Score=338, Expect=1e-95]; ENSG00000105464, GRIN2D, glutamate ionotropic receptor NMDA type subunit 2D, [RH, Score=330, Expect=1e-93]} {Mouse: ENSMUSG00000059003, Grin2a, glutamate receptor, ionotropic, NMDA2A (epsilon 1), [RH, Score=347, Expect=4e-99]; ENSMUSG00000020734, Grin2c, glutamate receptor, ionotropic, NMDA2C (epsilon 3), [RH, Score=343, Expect=2e-98]; ENSMUSG00000030209, Grin2b, glutamate receptor, ionotropic, NMDA2B (epsilon 2), [RH, Score=339, Expect=2e-96]; ENSMUSG00000002771, Grin2d, glutamate receptor, ionotropic, NMDA2D (epsilon 4), [RH, Score=331, Expect=5e-94]} {Dmel: FBgn0053513, Nmdar2, NMDA receptor 2, [RH, Score=530, Expect=2e-168]} {Celegans: WBGene00003775, nmr-2, NMDA class glutamate Receptor; NMDA-type ionotropic glutamate receptor NMR-2, [RH, Score=461, Expect=8e-144]} {Smed: dd_Smed_v6_11481_0_1, dd_Smed_v6_11481_0_1, [RH, Score=871, Expect=0.0]} {RNA1509_56620} {RNA1310_18260, RNA1509_56620} {RNA1509_56620, RNA815_11857}
4. MligTC455_26713 1834 38.2 Mlig455_062582

Neo: -

Age: Down-Up-Up

Region-enriched R6: 1.015/0.03194

RHOA 0.961 - - - - 0.961 - Mlig455_062582 {REF} {Length: 1609} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=164.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=78.9]; ADP-ribosylation factor family [PF00025.23, score=30.2]; Signal recognition particle receptor beta subunit [PF09439.12, score=18.7]} {Human: ENSG00000067560, RHOA, ras homolog family member A, [Score=188, Expect=4e-60]; ENSG00000155366, RHOC, ras homolog family member C, [Score=183, Expect=4e-58]; ENSG00000143878, RHOB, ras homolog family member B, [Score=179, Expect=3e-56]} {Mouse: ENSMUSG00000007815, Rhoa, ras homolog family member A, [Score=188, Expect=2e-60]; ENSMUSG00000002233, Rhoc, ras homolog family member C, [Score=183, Expect=3e-58]; ENSMUSG00000036463, 4930544G11Rik, RIKEN cDNA 4930544G11 gene, [Score=181, Expect=3e-57]; ENSMUSG00000054364, Rhob, ras homolog family member B, [Score=179, Expect=2e-56]} {Dmel: FBgn0014020, Rho1, [Score=184, Expect=5e-59]} {Celegans: WBGene00004357, rho-1, Ras-like GTP-binding protein rhoA, [Score=182, Expect=2e-58]} {Smed: dd_Smed_v6_813_0_1, dd_Smed_v6_813_0_1, [Score=186, Expect=7e-60]} {RNA1509_22569, RNA1509_3247} {RNA1310_15563, RNA1509_22569, RNA1509_3247} {RNA1509_22569, RNA1509_3247, RNA815_8100}
5. MligTC455_35053 719 14.99 Mlig455_030771

Neo: Irradiation

Age: Up-Down-Up, logFC(26M/2M)=-0.400

Region-enriched R5: 2.154/0.00000

0.961 - - - 0.961 - - Mlig455_030771 {REF} {Length: 3903} {Pfam: OST-HTH/LOTUS domain [PF12872.9, score=35.3]} {RNA1509_18110} {RNA1310_20306} {RNA815_4730}
6. MligTC455_35495 586 12.21 Mlig455_023069

Neo: -

Age: -

PCF11 0.961 - - - 0.961 - - Mlig455_023069 {REF} {Length: 4117} {TRANSSPLICED} {Pfam: CID domain [PF04818.15, score=32.6]} {Human: ENSG00000165494, PCF11, PCF11, cleavage and polyadenylation factor subunit, [RH, Score=91.3, Expect=6e-18]} {Mouse: ENSMUSG00000041328, Pcf11, PCF11 cleavage and polyadenylation factor subunit, [RH, Score=92.4, Expect=2e-18]} {Dmel: FBgn0264962, Pcf11, Protein 1 of cleavage and polyadenylation factor 1, [Score=78.6, Expect=3e-14]} {Smed: dd_Smed_v6_3280_0_1, dd_Smed_v6_3280_0_1, [RH, Score=191, Expect=3e-50]} {RNA1509_13594} {RNA1310_1865.1} {RNA815_5333}
7. MligTC455_12654 82 1.72 Mlig455_019923

Neo: -

Age: -

0.959 - - - - 0.959 - Mlig455_019923 {REF} {Length: 853} {RNA1509_54363} {RNA1310_57594, RNA1509_54363} {RNA1509_54363, RNA815_31588}
8. MligTC455_20789 403 8.41 Mlig455_068118

Neo: Int S/G2/M

Age: -

UBE2J1 0.958 - - - - 0.958 - Mlig455_068118 {REF} {Length: 2229} {TRANSSPLICED} {Pfam: Ubiquitin-conjugating enzyme [PF00179.28, score=65.5]} {Human: ENSG00000198833, UBE2J1, ubiquitin conjugating enzyme E2 J1, [RH, Score=260, Expect=5e-85]} {Mouse: ENSMUSG00000028277, Ube2j1, ubiquitin-conjugating enzyme E2J 1, [RH, Score=263, Expect=2e-86]} {Dmel: FBgn0038515, CG5823, [Score=125, Expect=8e-34]} {Celegans: WBGene00006703, ubc-6, UBiquitin Conjugating enzyme, [RH, Score=263, Expect=1e-86]} {Smed: dd_Smed_v6_2788_0_1, dd_Smed_v6_2788_0_1, [RH, Score=303, Expect=3e-101]} {RNA1509_11687} {RNA1310_24163} {RNA815_16666}
9. MligTC455_45084 716 14.92 Mlig455_064474

Neo: -

Age: -

ASNA1 0.958 - - - 0.958 - - Mlig455_064474 {REF} {Length: 3329} {TRANSSPLICED} {Pfam: Anion-transporting ATPase [PF02374.17, score=366.2]; CobQ/CobB/MinD/ParA nucleotide binding domain [PF01656.25, score=34.0]; AAA domain [PF13614.8, score=31.4]; NUBPL iron-transfer P-loop NTPase [PF10609.11, score=20.9]} {Human: ENSG00000198356, ASNA1, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial), [RH, Score=418, Expect=1e-146]} {Mouse: ENSMUSG00000052456, Asna1, arsA arsenite transporter, ATP-binding, homolog 1 (bacterial), [RH, Score=417, Expect=4e-146]} {Dmel: FBgn0033191, CG1598, [RH, Score=402, Expect=1e-140]} {Celegans: WBGene00014025, asna-1, ATPase asna-1, [RH, Score=304, Expect=3e-102]} {Smed: dd_Smed_v6_4084_0_1, dd_Smed_v6_4084_0_1, [RH, Score=362, Expect=2e-125]} {RNA1509_22091, RNA1509_37274, RNA1509_48504, RNA1509_57418} {RNA1310_24571, RNA1509_22091, RNA1509_37274, RNA1509_48504, RNA1509_57418} {RNA1509_22091, RNA1509_37274, RNA1509_48504, RNA1509_57418, RNA815_26767}
10. MligTC455_46162 320 6.67 Mlig455_008014

Neo: -

Age: Down-Up-Down

0.958 - - - - - 0.958 Mlig455_008014 {REF} {Length: 1913} {RNA1509_43120} {RNA1310_22234, RNA1509_43120} {RNA1509_43120, RNA815_35898}
11. MligTC455_50106 707 14.74 Mlig455_065336

Neo: -

Age: logFC(26M/2M)=0.165

KDELR2 0.957 - - - 0.957 - - Mlig455_065336 {REF} {Length: 2637} {TRANSSPLICED} {Pfam: ER lumen protein retaining receptor [PF00810.20, score=192.3]} {Human: ENSG00000136240, KDELR2, KDEL endoplasmic reticulum protein retention receptor 2, [RH, Score=325, Expect=4e-114]} {Mouse: ENSMUSG00000079111, Kdelr2, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, [RH, Score=325, Expect=4e-114]} {Dmel: FBgn0267330, KdelR, KDEL receptor, [RH, Score=335, Expect=3e-118]} {Celegans: WBGene00001331, erd-2, ER lumen protein-retaining receptor, [RH, Score=300, Expect=9e-105]} {Smed: dd_Smed_v6_1592_0_1, dd_Smed_v6_1592_0_1, [RH, Score=342, Expect=2e-121]} {RNA1509_18720, RNA1509_19108, RNA1509_29538, RNA1509_35523, RNA1509_38943, RNA1509_48642, RNA1509_5339} {RNA1310_15335, RNA1509_18720, RNA1509_19108, RNA1509_29538, RNA1509_35523, RNA1509_38943, RNA1509_48642, RNA1509_5339} {RNA1509_18720, RNA1509_19108, RNA1509_29538, RNA1509_35523, RNA1509_38943, RNA1509_48642, RNA1509_5339, RNA815_5191}
12. MligTC455_40828 172 3.59 Mlig455_004004

Neo: -

Age: -

PRR9 0.953 - - - - 0.953 - Mlig455_004004 {REF} {Length: 3347} {TRANSSPLICED} {Human: ENSG00000203783, PRR9, proline rich 9, [Score=45.4, Expect=1e-05]} {Mouse: ENSMUSG00000024246, Thumpd2, THUMP domain containing 2, [Score=56.2, Expect=4e-08]} {Celegans: WBGene00018026, F35A5.4, [Score=59.7, Expect=2e-09]} {RNA1509_48842} {RNA1310_15248} {RNA815_5852}
13. MligTC455_35510 1258 26.21 Mlig455_028059

Neo: -

Age: Down-Down-Up

Region-enriched R4: 1.203/0.04531

0.952 - - - - 0.952 - Mlig455_028059 {REF} {Length: 2589} {RNA1509_24909, RNA1509_39498, RNA1509_49041, RNA1509_7021} {RNA1310_23776, RNA1509_24909, RNA1509_39498, RNA1509_49041} {RNA1509_24909, RNA1509_39498, RNA1509_49041, RNA815_13425.1}
14. MligTC455_52304 832 17.34 Mlig455_000381

Neo: -

Age: -

Regeneration-upregulated BL: 2.051

Regeneration-enriched BL: 2.051

SETD2 0.952 - - - 0.952 - - Mlig455_000381 {REF} {Length: 6671} {TRANSSPLICED} {Pfam: SRI (Set2 Rpb1 interacting) domain [PF08236.13, score=55.4]; AWS domain [PF17907.3, score=41.0]; WW domain [PF00397.28, score=28.1]; SET domain [PF00856.30, score=22.8]} {Human: ENSG00000181555, SETD2, SET domain containing 2, [Score=148, Expect=9e-35]} {Mouse: ENSMUSG00000044791, Setd2, SET domain containing 2, [Score=151, Expect=8e-36]} {Dmel: FBgn0030486, Set2, SET domain containing 2, [Score=119, Expect=4e-26]} {Celegans: WBGene00003040, lin-59, Probable histone-lysine N-methyltransferase lin-59, [Score=73.2, Expect=2e-12]} {Smed: dd_Smed_v6_10742_0_1, dd_Smed_v6_10742_0_1, [Score=157, Expect=5e-38]} {RNA1509_40884, RNA1509_46851} {RNA1310_803, RNA1509_40884} {RNA1509_40884, RNA815_9944}
15. MligTC455_42680 1410 29.37 Mlig455_057043

Neo: -

Age: -

0.951 - - - 0.951 - - Mlig455_057043 {REF} {Length: 1934} {NoTransDecoderORF} {RNA1509_20619} {RNA1310_24331.1} {RNA815_10810.1}
16. MligTC455_39673 301 6.27 Mlig455_032019

Neo: -

Age: logFC(26M/2M)=-0.502

RAP2B 0.95 - - - - 0.950 - Mlig455_032019 {REF} {Length: 2377} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=185.0]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=72.2]; ADP-ribosylation factor family [PF00025.23, score=38.3]; RsgA GTPase [PF03193.18, score=26.7]; 50S ribosome-binding GTPase [PF01926.25, score=21.4]; Elongation factor Tu GTP binding domain [PF00009.29, score=19.7]} {Human: ENSG00000181467, RAP2B, RAP2B, member of RAS oncogene family, [Score=214, Expect=4e-71]; ENSG00000127314, RAP1B, RAP1B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSG00000123728, RAP2C, RAP2C, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000116473, RAP1A, RAP1A, member of RAS oncogene family, [Score=209, Expect=4e-69]; ENSG00000125249, RAP2A, RAP2A, member of RAS oncogene family, [Score=206, Expect=4e-68]} {Mouse: ENSMUSG00000051615, Rap2a, RAS related protein 2a, [Score=215, Expect=7e-72]; ENSMUSG00000036894, Rap2b, RAP2B, member of RAS oncogene family, [Score=214, Expect=3e-71]; ENSMUSG00000052681, Rap1b, RAS related protein 1b, [Score=214, Expect=2e-71]; ENSMUSG00000050029, Rap2c, RAP2C, member of RAS oncogene family, [Score=209, Expect=2e-69]; ENSMUSG00000068798, Rap1a, RAS-related protein 1a, [Score=209, Expect=3e-69]} {Dmel: FBgn0004636, Rap1, Rap1 GTPase, [Score=208, Expect=4e-69]} {Celegans: WBGene00004308, rap-2, RAP homolog (Vertebrate Rap GTPase family), [RH, Score=222, Expect=1e-74]} {Smed: dd_Smed_v6_1239_0_1, dd_Smed_v6_1239_0_1, [Score=207, Expect=9e-69]} {RNA1509_19937} {RNA1310_3952} {RNA815_8102}

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