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Results for MligTC455_05144

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_05144 33 0.69 Mlig455_036438

Neo: -

Age: -

 Mlig455_036438 {REF} {Length: 891} {NoTransDecoderORF} {RNA1310_36060}

Cumulative graph for MligTC455_05144

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.752 0.768 0.99972 1.00000
RegionR2 0.173 0.768 0.99991 1.00000
RegionR3 1.056 0.768 0.99999 1.00000
RegionR4 0.189 0.768 0.99988 1.00000
RegionR5 1.007 0.768 0.99990 1.00000
RegionR6 0.347 0.768 0.99994 1.00000
RegionR7 -0.123 0.768 1.00000 1.00000
RegionR8 -0.897 0.768 0.99991 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.292 0.768 0.99995 1.00000
RegenerationR2 3.493 0.768 0.10548 0.51085
RegenerationR3 1.456 0.768 0.21109 0.64765
RegenerationR4 1.288 0.768 0.28106 0.72620
RegenerationR5 -0.93 0.768 0.99996 1.00000
RegenerationR6 3.242 0.768 0.08844 0.37129
RegenerationBL 3.936 0.768 0.10481 0.38219
RegenerationTP -0.15 0.768 0.99998 1.00000


Genes with expression patterns similar to MligTC455_05144

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_05144 33 0.69 Mlig455_036438

Neo: -

Age: -

 1 - - - - 1.000 - Mlig455_036438 {REF} {Length: 891} {NoTransDecoderORF} {RNA1310_36060}
2. MligTC455_28901 2683 55.89 Mlig455_000702, Mlig455_000756

Neo: -

Age: -

 CNTRL 0.983 - - - - 0.983 -

Mlig455_000702 {REF} {Length: 7735} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=68.9]; Leucine Rich repeats (2 copies) [PF12799.9, score=62.9]; Leucine rich repeat [PF13855.8, score=47.3]; Crescentin protein [PF19220.2, score=23.5]} {Human: ENSG00000119397, CNTRL, centriolin, [Score=217, Expect=9e-56]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [Score=217, Expect=7e-56]} {Dmel: FBgn0032163, TbCMF46, [Score=85.5, Expect=3e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [Score=189, Expect=6e-48]} {RNA1509_7114} {RNA1310_12566} {RNA815_3884}

Mlig455_000756 {REF} {Length: 7584} {TRANSSPLICED} {Pfam: Leucine-rich repeat [PF14580.8, score=65.5]; Leucine Rich repeats (2 copies) [PF12799.9, score=61.9]; Leucine rich repeat [PF13855.8, score=45.8]} {Human: ENSG00000119397, CNTRL, centriolin, [RH, Score=254, Expect=4e-67]} {Mouse: ENSMUSG00000057110, Cntrl, centriolin, [RH, Score=257, Expect=4e-68]} {Dmel: FBgn0032163, TbCMF46, [Score=84.7, Expect=4e-16]} {Celegans: WBGene00015516, C06A8.6, [Score=78.2, Expect=1e-14]} {Smed: dd_Smed_v6_10369_0_1, dd_Smed_v6_10369_0_1, [RH, Score=199, Expect=9e-51]} {RNA1509_40686, RNA1509_7114} {RNA1310_1213, RNA1509_40686} {RNA1509_40686, RNA815_4518}
3. MligTC455_33217 350 7.3 Mlig455_017510, Mlig455_025979, Mlig455_030680, Mlig455_060677, Mlig455_070125

Neo: -

Age: Down-Up-Down

 0.982 - - - - 0.982 -

Mlig455_017510 {REF} {Length: 518} {NoTransDecoderORF} {RNA1509_35799} {RNA1310_37183} {RNA815_7155}

Mlig455_025979 {REF} {Length: 1819} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.1} {RNA815_7155}

Mlig455_030680 {REF} {Length: 1230} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_060677 {REF} {Length: 6928} {NoTransDecoderORF} {RNA1509_33795, RNA1509_44389} {RNA1310_14765.2, RNA1509_33795} {RNA1509_33795, RNA815_7155}

Mlig455_070125 {REF} {Length: 5305} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
4. MligTC455_44971 99 2.07 Mlig455_055696

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.674

Region-enriched R4: 4.753/0.00442

 ATP1B1 0.979 - - - - 0.979 - Mlig455_055696 {REF} {Length: 2498} {TRANSSPLICED} {Pfam: Sodium / potassium ATPase beta chain [PF00287.20, score=206.1]} {Human: ENSG00000143153, ATP1B1, ATPase Na+/K+ transporting subunit beta 1, [RH, Score=125, Expect=7e-33]} {Mouse: ENSMUSG00000026576, Atp1b1, ATPase, Na+/K+ transporting, beta 1 polypeptide, [RH, Score=127, Expect=8e-34]} {Dmel: FBgn0032946, nrv3, nervana 3, [RH, Score=164, Expect=8e-48]} {Celegans: WBGene00007646, nkb-1, Sodium/potassium-transporting ATPase subunit beta-1, [Score=151, Expect=4e-43]} {Smed: dd_Smed_v6_7917_0_1, dd_Smed_v6_7917_0_1, [RH, Score=244, Expect=2e-79]} {RNA1509_10526} {RNA1310_27937} {RNA815_16874}
5. MligTC455_21914 6688 139.34 Mlig455_041245, Mlig455_053092

Neo: -

Age: -

 FLNB 0.977 - - - - 0.977 -

Mlig455_041245 {REF} {Length: 5323} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=341.5]} {Human: ENSG00000136068, FLNB, filamin B, [Score=238, Expect=1e-62]; ENSG00000196924, FLNA, filamin A, [Score=230, Expect=3e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=243, Expect=1e-64]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=429, Expect=2e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=469, Expect=3e-139]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=265, Expect=2e-73]} {RNA1509_1061} {RNA1310_1557.1, RNA1509_1061} {RNA1509_1061, RNA815_236}

Mlig455_053092 {REF} {Length: 4805} {Pfam: Filamin/ABP280 repeat [PF00630.21, score=342.0]} {Human: ENSG00000136068, FLNB, filamin B, [Score=239, Expect=4e-63]; ENSG00000196924, FLNA, filamin A, [Score=231, Expect=2e-60]} {Mouse: ENSMUSG00000031328, Flna, filamin, alpha, [Score=244, Expect=9e-65]} {Dmel: FBgn0028371, jbug, jitterbug, [RH, Score=430, Expect=1e-124]} {Celegans: WBGene00016006, fln-2, FiLamiN (Actin binding protein) homolog, [RH, Score=471, Expect=8e-140]} {Smed: dd_Smed_v6_14262_0_1, dd_Smed_v6_14262_0_1, [RH, Score=267, Expect=2e-74]} {RNA1509_1061} {RNA1310_1557.1} {RNA815_236}
6. MligTC455_33706 819 17.07 Mlig455_008312

Neo: -

Age: -

 XRRA1 0.975 - - - - 0.975 - Mlig455_008312 {REF} {Length: 3552} {Pfam: Leucine Rich repeats (2 copies) [PF12799.9, score=41.9]; Leucine rich repeat [PF13855.8, score=29.4]} {Human: ENSG00000166435, XRRA1, X-ray radiation resistance associated 1, [RH, Score=163, Expect=3e-44]} {Mouse: ENSMUSG00000035211, Xrra1, X-ray radiation resistance associated 1, [RH, Score=171, Expect=1e-43]} {Smed: dd_Smed_v6_13519_0_1, dd_Smed_v6_13519_0_1, [RH, Score=154, Expect=5e-38]} {RNA1509_21148, RNA1509_45583} {RNA1310_16743.1, RNA1509_21148, RNA1509_45583} {RNA1509_21148, RNA1509_45583, RNA815_17679}
7. MligTC455_36003 363 7.55 Mlig455_026590

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.251

 DNAH6 0.974 - - - - 0.974 - Mlig455_026590 {REF} {Length: 15062} {TRANSSPLICED} {Pfam: Hydrolytic ATP binding site of dynein motor region [PF12774.9, score=480.2]; P-loop containing dynein motor region D4 [PF12780.9, score=291.4]; Dynein heavy chain C-terminal domain [PF18199.3, score=254.7]; ATP-binding dynein motor region [PF12781.9, score=232.9]; Dynein heavy chain, N-terminal region 2 [PF08393.15, score=229.2]; P-loop containing dynein motor region [PF12775.9, score=203.3]; Microtubule-binding stalk of dynein motor [PF12777.9, score=125.5]; Dynein heavy chain AAA lid domain [PF18198.3, score=122.2]; Dynein heavy chain region D6 P-loop domain [PF03028.17, score=112.7]; Dynein heavy chain AAA lid domain [PF17852.3, score=85.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=50.9]; AAA domain [PF13401.8, score=49.6]; AAA ATPase domain [PF13191.8, score=46.7]; AAA+ lid domain [PF17857.3, score=46.7]; ATPase family associated with various cellular activities (AAA) [PF00004.31, score=45.9]; AAA domain [PF13238.8, score=23.0]; AAA domain [PF13671.8, score=20.8]; NACHT domain [PF05729.14, score=20.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=19.7]} {Human: ENSG00000115423, DNAH6, dynein axonemal heavy chain 6, [Score=1591, Expect=0.0]; ENSG00000185842, DNAH14, dynein axonemal heavy chain 14, [Score=1554, Expect=0.0]} {Mouse: ENSMUSG00000052861, Dnah6, dynein, axonemal, heavy chain 6, [Score=1545, Expect=0.0]} {Dmel: FBgn0283476, Dhc16F, Dynein heavy chain at 16F, [Score=1207, Expect=0.0]} {Celegans: WBGene00000962, dhc-1, Dynein heavy chain, cytoplasmic, [Score=628, Expect=5e-180]} {Smed: dd_Smed_v6_10969_0_1, dd_Smed_v6_10969_0_1, [RH, Score=2792, Expect=0.0]} {RNA1509_3937, RNA1509_49112} {RNA1310_38.1, RNA1509_49112} {RNA1509_49112, RNA815_142}
8. MligTC455_38921 1688 35.17 Mlig455_023977

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.453

 MX2 0.973 - - - - 0.973 - Mlig455_023977 {REF} {Length: 3870} {Pfam: Dynamin central region [PF01031.22, score=175.3]; Dynamin family [PF00350.25, score=125.4]; Dynamin GTPase effector domain [PF02212.20, score=47.1]; 50S ribosome-binding GTPase [PF01926.25, score=22.3]; AAA ATPase domain [PF13191.8, score=19.2]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [Score=319, Expect=2e-97]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [Score=307, Expect=8e-94]} {Dmel: FBgn0003392, shi, shibire, [Score=181, Expect=2e-47]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=177, Expect=3e-46]} {Smed: dd_Smed_v6_2583_0_1, dd_Smed_v6_2583_0_1, [Score=194, Expect=3e-52]} {RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1310_6542.1, RNA1509_17985, RNA1509_34505, RNA1509_40252} {RNA1509_17985, RNA1509_34505, RNA1509_40252, RNA815_1426.1}
9. MligTC455_22397 123 2.55 Mlig455_007094, Mlig455_008909, Mlig455_015478, Mlig455_016547, Mlig455_037908, Mlig455_038997, Mlig455_051315

Neo: -

Age: -

 0.971 - - - - 0.971 -

Mlig455_007094 {REF} {Length: 1370} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_008909 {REF} {Length: 529} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_015478 {REF} {Length: 1396} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_016547 {REF} {Length: 518} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_037908 {REF} {Length: 4536} {RNA1509_32371} {RNA1310_7877} {RNA815_19983}

Mlig455_038997 {REF} {Length: 520} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_56212} {RNA1310_28962.1} {RNA815_25104.1}

Mlig455_051315 {REF} {Length: 240} {NoTransDecoderORF} {RNA1509_51049} {RNA1310_28962.1} {RNA815_23816.2}
10. MligTC455_31890 210 4.38 Mlig455_070942

Neo: -

Age: logFC(26M/2M)=-0.564

 0.97 - - - - 0.970 - Mlig455_070942 {REF} {Length: 2335} {Pfam: MULE transposase domain [PF10551.11, score=21.4]; Domain of unknown function (DUF4806) [PF16064.7, score=19.0]} {Smed: dd_Smed_v6_24877_0_1, dd_Smed_v6_24877_0_1, [Score=52.0, Expect=2e-08]} {RNA1509_28268} {RNA1310_1293.1} {RNA815_1077}
11. MligTC455_30256 48 0.99 Mlig455_003751, Mlig455_053129

Neo: -

Age: logFC(26M/2M)=-2.069

 0.969 - - - - 0.969 -

Mlig455_003751 {REF} {Length: 2349} {TRANSSPLICED} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=53.4]} {Smed: dd_Smed_v6_18385_0_1, dd_Smed_v6_18385_0_1, [Score=89.0, Expect=7e-20]} {RNA1509_31144} {RNA1310_15076.1} {RNA815_5159.1}

Mlig455_053129 {REF} {Length: 2316} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=24.2]} {RNA1509_31144, RNA1509_40622} {RNA1310_15076.1, RNA1509_40622} {RNA1509_40622, RNA815_5159.1}
12. MligTC455_39145 860 17.92 Mlig455_045710

Neo: -

Age: Down-Up-Down

Region-enriched R2: 1.035/0.04635

 0.968 - - - - 0.968 - Mlig455_045710 {REF} {Length: 2657} {Pfam: Family of unknown function (DUF5580) [PF17743.3, score=80.4]} {Smed: dd_Smed_v6_9326_0_1, dd_Smed_v6_9326_0_1, [RH, Score=180, Expect=1e-49]} {RNA1509_11160, RNA1509_32698} {RNA1310_8387, RNA1509_11160, RNA1509_32698} {RNA1509_11160, RNA1509_32698, RNA815_15696.1}
13. MligTC455_21470 491 10.23 Mlig455_028994

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.236

 KCNMA1 0.967 - - - - 0.967 - Mlig455_028994 {REF} {Length: 4059} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=82.1]; Ion channel [PF07885.18, score=48.7]; Ion transport protein [PF00520.33, score=31.6]; TrkA-N domain [PF02254.20, score=27.3]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=484, Expect=1e-151]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=482, Expect=5e-151]} {Dmel: FBgn0003429, slo, slowpoke, [Score=479, Expect=1e-150]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=461, Expect=5e-144]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=490, Expect=3e-155]} {RNA1509_10617} {RNA1310_2480.1} {RNA815_984.1}
14. MligTC455_50996 449 9.36 Mlig455_002019

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=-0.319

Region-enriched R2: 1.520/0.04245

 TRIM71 0.967 - - - - 0.967 - Mlig455_002019 {REF} {Length: 2281} {Pfam: NHL repeat [PF01436.23, score=74.6]} {Human: ENSG00000206557, TRIM71, tripartite motif containing 71, [Score=79.3, Expect=3e-15]; ENSG00000109654, TRIM2, tripartite motif containing 2, [Score=76.3, Expect=3e-14]} {Mouse: ENSMUSG00000079259, Trim71, tripartite motif-containing 71, [Score=79.7, Expect=2e-15]; ENSMUSG00000027993, Trim2, tripartite motif-containing 2, [Score=76.3, Expect=2e-14]} {Dmel: FBgn0265356, tn, thin, [Score=94.0, Expect=3e-20]} {Celegans: WBGene00003026, lin-41, [Score=80.5, Expect=5e-16]} {Smed: dd_Smed_v6_13659_0_1, dd_Smed_v6_13659_0_1, [RH, Score=102, Expect=2e-24]} {RNA1509_17378} {RNA1310_19512.1, RNA1509_17378} {RNA1509_17378, RNA815_7968}
15. MligTC455_52118 5757 119.94 Mlig455_069122

Neo: -

Age: logFC(26M/2M)=0.892

 CFAP58 0.967 - - - - 0.967 - Mlig455_069122 {REF} {Length: 3136} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=23.0]} {Human: ENSG00000120051, CFAP58, cilia and flagella associated protein 58, [RH, Score=923, Expect=0.0]} {Mouse: ENSMUSG00000046585, Cfap58, cilia and flagella associated protein 58, [RH, Score=991, Expect=0.0]} {Dmel: FBgn0039490, CG5882, [RH, Score=162, Expect=1e-40]} {Celegans: WBGene00001328, epi-1, Laminin-like protein epi-1, [Score=57.8, Expect=4e-08]} {Smed: dd_Smed_v6_5727_0_1, dd_Smed_v6_5727_0_1, [RH, Score=1103, Expect=0.0]} {RNA1509_282} {RNA1310_4570, RNA1509_282} {RNA1509_282, RNA815_1528}
16. MligTC455_07849 33 0.7 Mlig455_026748

Neo: -

Age: -

 0.966 - - - - 0.966 - Mlig455_026748 {REF} {Length: 1120} {NoTransDecoderORF}
17. MligTC455_33364 348 7.24 Mlig455_009410, Mlig455_016109, Mlig455_026502, Mlig455_027903, Mlig455_036913, Mlig455_066713, Mlig455_068644, Mlig455_070501

Neo: -

Age: logFC(26M/2M)=-0.641

 NYNRIN 0.966 - - - - 0.966 -

Mlig455_009410 {REF} {Length: 6826} {TRANSSPLICED} {Pfam: Innexin [PF00876.20, score=304.8]} {Dmel: FBgn0027108, Inx2, Innexin 2, [Score=92.4, Expect=4e-20]} {Celegans: WBGene00006749, unc-9, Innexin unc-9, [Score=209, Expect=1e-62]} {Smed: dd_Smed_v6_10766_0_1, dd_Smed_v6_10766_0_1, [Score=301, Expect=1e-97]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_016109 {REF} {Length: 3482} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.5]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.8]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=55.7]; Aspartyl protease [PF13650.8, score=21.8]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=7e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=124, Expect=4e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=425, Expect=7e-131]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}

Mlig455_026502 {REF} {Length: 698} {Pfam: Zinc knuckle [PF00098.25, score=27.8]} {RNA1509_38652} {RNA1310_25149.1} {RNA815_13280}

Mlig455_027903 {REF} {Length: 3748} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.1]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=84.7]; Integrase zinc binding domain [PF17921.3, score=79.0]; Integrase core domain [PF00665.28, score=51.2]; Aspartyl protease [PF13650.8, score=21.9]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.3]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=121, Expect=5e-27]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=122, Expect=1e-27]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=432, Expect=8e-134]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_036913 {REF} {Length: 639} {RNA1509_48973} {RNA1310_39833} {RNA815_36286}

Mlig455_066713 {REF} {Length: 2873} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=122.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.1]; Integrase zinc binding domain [PF17921.3, score=77.1]; Integrase core domain [PF00665.28, score=53.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=117, Expect=3e-26]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=117, Expect=4e-26]} {Smed: dd_Smed_v6_6563_0_1, dd_Smed_v6_6563_0_1, [Score=237, Expect=1e-65]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_068644 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=124.8]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=122.2]; Integrase zinc binding domain [PF17921.3, score=79.7]; Integrase core domain [PF00665.28, score=49.0]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=130, Expect=4e-30]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=6e-29]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=313, Expect=5e-93]} {RNA1509_38652} {RNA1310_6256} {RNA815_10502}

Mlig455_070501 {REF} {Length: 2339} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=123.7]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=121.2]; Integrase zinc binding domain [PF17921.3, score=76.5]; Integrase core domain [PF00665.28, score=54.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=47.6]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [RH, Score=124, Expect=2e-28]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [RH, Score=125, Expect=1e-28]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=322, Expect=2e-96]} {RNA1509_26990} {RNA1310_6256} {RNA815_10502}
18. MligTC455_49877 188 3.91 Mlig455_027465

Neo: -

Age: -

Region-enriched R2: 3.005/0.04141

 AC254952.1 0.966 - - - - 0.966 - Mlig455_027465 {REF} {Length: 2059} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=89.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=80.0]} {Human: ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=6e-38]; ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=144, Expect=1e-37]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=144, Expect=9e-38]; ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=141, Expect=2e-36]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=141, Expect=1e-36]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=141, Expect=6e-37]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=139, Expect=5e-36]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=134, Expect=2e-34]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=132, Expect=4e-33]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=126, Expect=6e-32]} {Smed: dd_Smed_v6_31300_0_1, dd_Smed_v6_31300_0_1, [Score=131, Expect=2e-33]} {RNA1310_26175} {RNA815_7952}
19. MligTC455_20886 97 2.02 Mlig455_003090

Neo: -

Age: -

 0.965 - - - - 0.965 - Mlig455_003090 {REF} {Length: 913} {NoTransDecoderORF} {RNA1310_65713.1} {RNA815_44606}
20. MligTC455_21673 316 6.58 Mlig455_013782, Mlig455_013911

Neo: -

Age: -

 0.964 - - - - 0.964 -

Mlig455_013782 {REF} {Length: 3170} {Pfam: Ras association (RalGDS/AF-6) domain [PF00788.25, score=47.1]} {Dmel: FBgn0031745, rau, [RH, Score=72.8, Expect=4e-13]} {RNA1509_28308} {RNA1310_8072} {RNA815_15473}

Mlig455_013911 {REF} {Length: 3190} {Pfam: Ras association (RalGDS/AF-6) domain [PF00788.25, score=46.0]} {Dmel: FBgn0031745, rau, [RH, Score=76.3, Expect=3e-14]} {RNA1509_28308} {RNA1310_8072, RNA1509_28308} {RNA1509_28308, RNA815_15473}
21. MligTC455_23078 287 5.98 Mlig455_011747

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.620

 CUBN 0.964 - - - - 0.964 - Mlig455_011747 {REF} {Length: 2191} {Pfam: EGF-like domain [PF00008.29, score=33.3]} {Human: ENSG00000107611, CUBN, cubilin, [Score=50.8, Expect=1e-06]} {Mouse: ENSMUSG00000049252, Lrp1b, low density lipoprotein-related protein 1B (deleted in tumors), [Score=53.9, Expect=7e-08]; ENSMUSG00000047793, Sned1, sushi, nidogen and EGF-like domains 1, [Score=52.4, Expect=2e-07]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=53.9, Expect=3e-08]} {RNA1509_38266} {RNA1310_23149} {RNA815_9585.1}
22. MligTC455_31292 287 5.97 Mlig455_059964

Neo: -

Age: logFC(26M/2M)=-0.518

 0.964 - - - - 0.964 - Mlig455_059964 {REF} {Length: 6272} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4549) [PF15082.8, score=142.8]; Ligand-gated ion channel [PF00060.28, score=50.1]} {Mouse: ENSMUSG00000075225, Ccdc162, coiled-coil domain containing 162, [Score=914, Expect=0.0]} {Dmel: FBgn0052704, Ir8a, Ionotropic receptor 8a, [Score=55.5, Expect=5e-07]} {Celegans: WBGene00001618, glr-7, GLutamate Receptor family (AMPA), [Score=58.2, Expect=6e-08]} {Smed: dd_Smed_v6_16643_0_1, dd_Smed_v6_16643_0_1, [RH, Score=706, Expect=0.0]} {RNA1509_21772} {RNA1310_311.1} {RNA815_144.1}
23. MligTC455_32487 595 12.39 Mlig455_017119

Neo: -

Age: logFC(26M/2M)=-0.391

 0.964 - - - - 0.964 - Mlig455_017119 {REF} {Length: 2322} {RNA1509_10657} {RNA1310_11689, RNA1509_10657} {RNA1509_10657, RNA815_5499}
24. MligTC455_30290 738 15.38 Mlig455_023808

Neo: -

Age: Up-Down-Up

 DST 0.963 - - - - 0.963 - Mlig455_023808 {REF} {Length: 23754} {Pfam: Domain of unknown function (DUF1851) [PF08906.13, score=48.1]; D-amino acid oxidase activator [PF15199.8, score=40.8]; SH3 domain [PF17902.3, score=39.4]; Carbohydrate/starch-binding module (family 21) [PF03370.15, score=28.2]} {Human: ENSG00000151914, DST, dystonin, [RH, Score=74.7, Expect=2e-12]} {Mouse: ENSMUSG00000026131, Dst, dystonin, [RH, Score=73.6, Expect=4e-12]} {Dmel: FBgn0013733, shot, short stop, [Score=87.0, Expect=2e-16]} {Celegans: WBGene00006876, vab-10, VAB-10B protein, [Score=52.4, Expect=5e-06]} {Smed: dd_Smed_v6_8220_0_4, dd_Smed_v6_8220_0_4, [Score=160, Expect=4e-39]} {RNA1509_41993} {RNA1310_3340.2} {RNA815_578.1}
25. MligTC455_52239 629 13.1 Mlig455_029233

Neo: -

Age: logFC(26M/2M)=-0.429

 ABCG2 0.963 - - - - 0.963 - Mlig455_029233 {REF} {Length: 3918} {Pfam: ABC-2 type transporter [PF01061.26, score=125.2]; ABC transporter [PF00005.29, score=73.3]; ABC-2 type transporter [PF19055.2, score=43.6]; AAA domain, putative AbiEii toxin, Type IV TA system [PF13304.8, score=31.5]; RecF/RecN/SMC N terminal domain [PF02463.21, score=23.9]; AAA domain [PF13476.8, score=20.9]} {Human: ENSG00000118777, ABCG2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=541, Expect=0.0]} {Mouse: ENSMUSG00000029802, Abcg2, ATP binding cassette subfamily G member 2 (Junior blood group), [Score=546, Expect=0.0]} {Dmel: FBgn0003996, w, white, [Score=257, Expect=4e-74]} {Celegans: WBGene00012925, wht-8, WHiTe (Drosophila) related ABC transporter, [RH, Score=259, Expect=1e-75]} {Smed: dd_Smed_v6_4225_0_2, dd_Smed_v6_4225_0_2, [RH, Score=689, Expect=0.0]} {RNA1509_2851} {RNA1310_949.2} {RNA815_1895}
26. MligTC455_19939 22 0.45 Mlig455_011563

Neo: -

Age: -

 0.962 - - - - 0.962 - Mlig455_011563 {REF} {Length: 867} {NoTransDecoderORF} {RNA1310_143071} {RNA815_42689}
27. MligTC455_34563 86 1.79 Mlig455_020138

Neo: -

Age: Down-Up-Down

 VASH2 0.962 - - - - 0.962 - Mlig455_020138 {REF} {Length: 2429} {Pfam: Vasohibin [PF14822.8, score=316.4]} {Human: ENSG00000143494, VASH2, vasohibin 2, [RH, Score=253, Expect=1e-81]; ENSG00000071246, VASH1, vasohibin 1, [RH, Score=252, Expect=2e-81]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=255, Expect=2e-82]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=252, Expect=2e-81]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=230, Expect=1e-73]} {RNA1509_59274} {RNA1310_23626.1, RNA1509_59274} {RNA1509_59274, RNA815_11698.1}
28. MligTC455_51903 1283 26.73 Mlig455_021657, Mlig455_067458

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=0.872

 CHRNB1, CHRNB3 0.962 - - - - 0.962 -

Mlig455_021657 {REF} {Length: 2044} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=73.5]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=193, Expect=5e-56]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=1e-54]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=187, Expect=8e-54]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=186, Expect=1e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=179, Expect=5e-51]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=176, Expect=3e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=9e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=346, Expect=9e-116]} {RNA1509_8724} {RNA1310_17144.1, RNA1509_8724} {RNA1509_8724, RNA815_6285}

Mlig455_067458 {REF} {Length: 1512} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=43.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=18.7]} {Human: ENSG00000283946, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000170175, CHRNB1, cholinergic receptor nicotinic beta 1 subunit, [Score=48.1, Expect=7e-06]; ENSG00000117971, CHRNB4, cholinergic receptor nicotinic beta 4 subunit, [Score=47.8, Expect=1e-05]} {Mouse: ENSMUSG00000029205, Chrna9, cholinergic receptor, nicotinic, alpha polypeptide 9, [Score=47.4, Expect=1e-05]} {Celegans: WBGene00000055, acr-16, Acetylcholine receptor subunit alpha-type acr-16, [Score=46.6, Expect=1e-05]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=96.7, Expect=1e-22]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
29. MligTC455_52121 259 5.39 Mlig455_064002, Mlig455_064040

Neo: -

Age: -

 MTMR14 0.962 - - - - 0.962 -

Mlig455_064002 {REF} {Length: 2473} {TRANSSPLICED} {Pfam: Myotubularin-like phosphatase domain [PF06602.16, score=23.7]} {Human: ENSG00000163719, MTMR14, myotubularin related protein 14, [Score=187, Expect=6e-53]} {Mouse: ENSMUSG00000030269, Mtmr14, myotubularin related protein 14, [Score=189, Expect=4e-53]} {Dmel: FBgn0027506, EDTP, Egg-derived tyrosine phosphatase, [Score=189, Expect=1e-52]} {Smed: dd_Smed_v6_6564_0_4, dd_Smed_v6_6564_0_4, [Score=208, Expect=7e-62]} {RNA1509_39844} {RNA1310_22218.1} {RNA815_24909}

Mlig455_064040 {REF} {Length: 2467} {TRANSSPLICED} {Pfam: Myotubularin-like phosphatase domain [PF06602.16, score=25.1]} {Human: ENSG00000163719, MTMR14, myotubularin related protein 14, [Score=183, Expect=1e-51]} {Mouse: ENSMUSG00000030269, Mtmr14, myotubularin related protein 14, [Score=185, Expect=1e-51]} {Dmel: FBgn0027506, EDTP, Egg-derived tyrosine phosphatase, [Score=190, Expect=4e-53]} {Smed: dd_Smed_v6_6564_0_4, dd_Smed_v6_6564_0_4, [Score=206, Expect=2e-61]} {RNA1509_39844} {RNA1310_22218.1, RNA1509_39844} {RNA1509_39844, RNA815_24909}
30. MligTC455_31889 414 8.63 Mlig455_027646, Mlig455_065376

Neo: -

Age: -

 0.961 - - - - 0.961 -

Mlig455_027646 {REF} {Length: 613} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4806) [PF16064.7, score=20.2]} {RNA1509_2283} {RNA1310_1293.1} {RNA815_1077}

Mlig455_065376 {REF} {Length: 615} {TRANSSPLICED} {RNA1509_37997} {RNA1310_1293.1} {RNA815_1077}
31. MligTC455_39608 6604 137.59 Mlig455_023921, Mlig455_046482

Neo: -

Age: -

 APP 0.961 - - - - 0.961 -

Mlig455_023921 {REF} {Length: 3702} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=48.7]; E2 domain of amyloid precursor protein [PF12925.9, score=43.8]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.1]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.3, Expect=3e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.0, Expect=3e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.9, Expect=6e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=101, Expect=4e-22]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=134, Expect=7e-33]} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1310_3149.1, RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900} {RNA1509_11651, RNA1509_19546, RNA1509_2244, RNA1509_31480, RNA1509_4900, RNA815_958.1}

Mlig455_046482 {REF} {Length: 3710} {TRANSSPLICED} {Pfam: Amyloid A4 N-terminal heparin-binding [PF02177.18, score=47.8]; E2 domain of amyloid precursor protein [PF12925.9, score=43.1]; Beta-amyloid precursor protein C-terminus [PF10515.11, score=40.8]; Copper-binding of amyloid precursor, CuBD [PF12924.9, score=39.2]} {Human: ENSG00000142192, APP, amyloid beta precursor protein, [Score=84.7, Expect=2e-16]} {Mouse: ENSMUSG00000022892, App, amyloid beta (A4) precursor protein, [Score=84.3, Expect=2e-16]} {Dmel: FBgn0000108, Appl, beta amyloid protein precursor-like, [Score=85.5, Expect=9e-17]} {Celegans: WBGene00000149, apl-1, Beta-amyloid-like protein, [RH, Score=103, Expect=9e-23]} {Smed: dd_Smed_v6_2561_0_1, dd_Smed_v6_2561_0_1, [RH, Score=138, Expect=3e-34]} {RNA1509_11651, RNA1509_35488} {RNA1310_3149.1, RNA1509_35488} {RNA1509_35488, RNA815_958.1}
32. MligTC455_54077 937 19.53 Mlig455_032159, Mlig455_032165

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.640

 TLL2 0.961 - - - - 0.961 -

Mlig455_032159 {REF} {Length: 1358} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}

Mlig455_032165 {REF} {Length: 1696} {Pfam: CUB domain [PF00431.22, score=63.7]} {Human: ENSG00000095587, TLL2, tolloid like 2, [Score=62.8, Expect=4e-10]; ENSG00000107611, CUBN, cubilin, [Score=62.0, Expect=1e-09]; ENSG00000038295, TLL1, tolloid like 1, [Score=61.2, Expect=1e-09]} {Mouse: ENSMUSG00000026726, Cubn, cubilin (intrinsic factor-cobalamin receptor), [Score=68.9, Expect=4e-12]} {Dmel: FBgn0004885, tok, tolkin, [Score=58.2, Expect=8e-09]} {Smed: dd_Smed_v6_5652_0_1, dd_Smed_v6_5652_0_1, [Score=61.2, Expect=4e-10]} {RNA1509_9300} {RNA1310_18452} {RNA815_8451}
33. MligTC455_21803 1070 22.29 Mlig455_051085

Neo: -

Age: Up-Down-Down, logFC(26M/2M)=-0.341

 0.96 - - - - 0.960 - Mlig455_051085 {REF} {Length: 13899} {TRANSSPLICED} {Smed: dd_Smed_v6_4420_0_2, dd_Smed_v6_4420_0_2, [Score=53.1, Expect=3e-06]} {RNA1509_25269} {RNA1310_284.1} {RNA815_96}
34. MligTC455_23565 3404 70.91 Mlig455_028825, Mlig455_028842

Neo: -

Age: logFC(26M/2M)=-0.382

 0.96 - - - - 0.960 -

Mlig455_028825 {REF} {Length: 4003} {TRANSSPLICED} {Smed: dd_Smed_v6_10823_0_2, dd_Smed_v6_10823_0_2, [Score=78.6, Expect=3e-15]} {RNA1509_2318} {RNA1310_2438.1} {RNA815_699}

Mlig455_028842 {REF} {Length: 3964} {TRANSSPLICED} {Pfam: Autophagy protein 16 (ATG16) [PF08614.13, score=19.8]} {Smed: dd_Smed_v6_10823_0_1, dd_Smed_v6_10823_0_1, [RH, Score=195, Expect=2e-50]} {RNA1509_2318} {RNA1310_2438.1, RNA1509_2318} {RNA1509_2318, RNA815_699}
35. MligTC455_30838 241 5.03 Mlig455_006342, Mlig455_006391

Neo: -

Age: logFC(26M/2M)=-0.590

 TRPM3 0.96 - - - - 0.960 -

Mlig455_006342 {REF} {Length: 5334} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=77.6]; Ankyrin repeats (many copies) [PF13637.8, score=68.2]; Ankyrin repeat [PF13606.8, score=47.7]; Ankyrin repeat [PF00023.32, score=43.1]; Ankyrin repeats (many copies) [PF13857.8, score=42.1]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=106, Expect=3e-22]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=107, Expect=9e-23]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=102, Expect=4e-21]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=96.7, Expect=1e-19]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=80.1, Expect=1e-14]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=118, Expect=1e-26]} {RNA1509_26663} {RNA1310_1128.1} {RNA815_4971}

Mlig455_006391 {REF} {Length: 5621} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=78.8]; Ankyrin repeats (many copies) [PF13637.8, score=69.5]; Ankyrin repeat [PF13606.8, score=49.1]; Ankyrin repeat [PF00023.32, score=44.4]; Ankyrin repeats (many copies) [PF13857.8, score=43.5]} {Human: ENSG00000083067, TRPM3, transient receptor potential cation channel subfamily M member 3, [Score=105, Expect=5e-22]} {Mouse: ENSMUSG00000052387, Trpm3, transient receptor potential cation channel, subfamily M, member 3, [Score=106, Expect=1e-22]; ENSMUSG00000030523, Trpm1, transient receptor potential cation channel, subfamily M, member 1, [Score=101, Expect=7e-21]} {Dmel: FBgn0265194, Trpm, Transient receptor potential cation channel, subfamily M, [Score=95.9, Expect=2e-19]} {Celegans: WBGene00001651, gon-2, Transient receptor potential channel, [Score=79.3, Expect=2e-14]} {Smed: dd_Smed_v6_26251_0_1, dd_Smed_v6_26251_0_1, [Score=119, Expect=6e-27]} {RNA1509_20834} {RNA1310_1128.1} {RNA815_4971}
36. MligTC455_43001 2139 44.57 Mlig455_004256, Mlig455_004325

Neo: -

Age: -

Region-enriched R2: 2.362/0.00019

 GLUD1 0.96 - - - - 0.960 -

Mlig455_004256 {REF} {Length: 1969} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=185.6]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=175.9]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=639, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=639, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=639, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=613, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=641, Expect=0.0]} {RNA1509_30743} {RNA1310_2661.2} {RNA815_713.2}

Mlig455_004325 {REF} {Length: 2236} {Pfam: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain [PF02812.20, score=185.5]; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase [PF00208.23, score=174.7]} {Human: ENSG00000148672, GLUD1, glutamate dehydrogenase 1, [Score=642, Expect=0.0]; ENSG00000182890, GLUD2, glutamate dehydrogenase 2, [Score=640, Expect=0.0]} {Mouse: ENSMUSG00000021794, Glud1, glutamate dehydrogenase 1, [Score=641, Expect=0.0]} {Dmel: FBgn0001098, Gdh, Glutamate dehydrogenase, [Score=613, Expect=0.0]} {Celegans: WBGene00014095, gdh-1, Glutamate dehydrogenase, [Score=558, Expect=0.0]} {Smed: dd_Smed_v6_932_0_1, dd_Smed_v6_932_0_1, [Score=639, Expect=0.0]} {RNA1509_10773, RNA1509_30743} {RNA1310_2661.2, RNA1509_10773, RNA1509_30743} {RNA1509_10773, RNA1509_30743, RNA815_713.2}
37. MligTC455_23843 66 1.38 Mlig455_000716

Neo: -

Age: -

 0.959 - - - - 0.959 - Mlig455_000716 {REF} {Length: 3789} {NoTransDecoderORF} {RNA1509_51543} {RNA1310_39627} {RNA815_33289}
38. MligTC455_43627 1683 35.07 Mlig455_012966

Neo: -

Age: -

 0.959 - - - - 0.959 - Mlig455_012966 {REF} {Length: 4640} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=231.1]} {Smed: dd_Smed_v6_19123_0_8, dd_Smed_v6_19123_0_8, [Score=73.9, Expect=2e-13]} {RNA1509_10570} {RNA1310_7155.1} {RNA815_1910.1}
39. MligTC455_44176 89 1.85 Mlig455_022911

Neo: -

Age: -

 TNKS 0.958 - - - - 0.958 - Mlig455_022911 {REF} {Length: 1883} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=67.0]; Ankyrin repeats (3 copies) [PF12796.9, score=64.6]; Ankyrin repeats (many copies) [PF13857.8, score=59.2]; Ankyrin repeat [PF13606.8, score=50.9]; Ankyrin repeat [PF00023.32, score=50.1]} {Human: ENSG00000173273, TNKS, tankyrase, [Score=57.8, Expect=3e-08]; ENSG00000285372, AC270292.3, tankyrase, [Score=56.6, Expect=7e-08]; ENSG00000236759, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000238134, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000204371, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000206376, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000227333, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000232045, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.8, Expect=1e-07]; ENSG00000224143, EHMT2, euchromatic histone lysine methyltransferase 2, [Score=55.5, Expect=2e-07]; ENSG00000029534, ANK1, ankyrin 1, [Score=55.5, Expect=2e-07]} {Mouse: ENSMUSG00000095294, Gm21119, predicted gene, 21119, [Score=57.8, Expect=1e-08]; ENSMUSG00000096265, 4930467E23Rik, RIKEN cDNA 4930467E23 gene, [Score=57.8, Expect=1e-08]; ENSMUSG00000031529, Tnks, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, [Score=57.8, Expect=2e-08]; ENSMUSG00000074449, Gm15319, predicted gene 15319, [Score=57.4, Expect=1e-08]; ENSMUSG00000013787, Ehmt2, euchromatic histone lysine N-methyltransferase 2, [Score=55.8, Expect=9e-08]; ENSMUSG00000063932, Poteg, POTE ankyrin domain family, member G, [Score=55.5, Expect=8e-08]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=55.5, Expect=1e-07]; ENSMUSG00000110591, Gm31371, predicted gene, 31371, [Score=55.5, Expect=4e-08]; ENSMUSG00000106824, Gm7697, predicted gene 7697, [Score=55.1, Expect=8e-08]; ENSMUSG00000107280, Gm9495, predicted gene 9495, [Score=55.1, Expect=8e-08]} {Dmel: FBgn0040752, Prosap, [Score=58.9, Expect=6e-09]} {Celegans: WBGene00001411, fem-1, Sex-determining protein fem-1, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_2072_0_22, dd_Smed_v6_2072_0_22, [Score=62.0, Expect=4e-10]} {RNA1509_39040} {RNA1310_19494} {RNA815_14632}
40. MligTC455_49179 1230 25.62 Mlig455_000575, Mlig455_030372

Neo: -

Age: Down-Up-Down

 GRIK1 0.958 - - - - 0.958 -

Mlig455_000575 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.4]; Receptor family ligand binding region [PF01094.30, score=21.2]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=66.2, Expect=9e-11]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.2, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885, RNA1509_5131} {RNA1509_5131, RNA815_1090.1}

Mlig455_030372 {REF} {Length: 3002} {Pfam: Ligand-gated ion channel [PF00060.28, score=56.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=22.5]; Receptor family ligand binding region [PF01094.30, score=21.4]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=76.6, Expect=1e-13]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=73.9, Expect=6e-13]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=73.2, Expect=1e-12]} {Celegans: WBGene00001613, glr-2, Glutamate receptor 2, [Score=65.5, Expect=1e-10]} {Smed: dd_Smed_v6_10048_0_1, dd_Smed_v6_10048_0_1, [Score=71.6, Expect=1e-12]} {RNA1509_5131} {RNA1310_3885} {RNA815_1090.1}
41. MligTC455_40437 142 2.96 Mlig455_007644

Neo: -

Age: logFC(26M/2M)=-0.263

 0.957 - - - - 0.957 - Mlig455_007644 {REF} {Length: 3098} {TRANSSPLICED} {Pfam: Fasciclin domain [PF02469.24, score=126.6]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=50.4, Expect=5e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=67.4, Expect=2e-11]} {RNA1509_10760} {RNA1310_4612.1} {RNA815_1343.1}
42. MligTC455_30192 1664 34.66 Mlig455_026693

Neo: -

Age: -

 FOXRED2 0.956 - - - - 0.956 - Mlig455_026693 {REF} {Length: 18036} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=147.7]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=45.8]; HI0933-like protein [PF03486.16, score=31.1]; FAD dependent oxidoreductase [PF01266.26, score=26.0]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=25.0]; FAD binding domain [PF01494.21, score=22.8]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=22.5]; Flavin containing amine oxidoreductase [PF01593.26, score=21.9]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=20.1]} {Human: ENSG00000100350, FOXRED2, FAD dependent oxidoreductase domain containing 2, [RH, Score=493, Expect=4e-167]} {Mouse: ENSMUSG00000016552, Foxred2, FAD-dependent oxidoreductase domain containing 2, [RH, Score=498, Expect=3e-169]} {Celegans: WBGene00001479, fmo-4, Flavin-containing monooxygenase, [Score=53.5, Expect=4e-07]} {Smed: dd_Smed_v6_12138_0_1, dd_Smed_v6_12138_0_1, [RH, Score=474, Expect=4e-161]} {RNA1509_13675, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1310_861.1, RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978} {RNA1509_19929, RNA1509_38216, RNA1509_56501, RNA1509_8978, RNA815_570.1}
43. MligTC455_38072 222 4.62 Mlig455_012098, Mlig455_023289, Mlig455_023290, Mlig455_030139

Neo: -

Age: -

 0.956 - - - - 0.956 -

Mlig455_012098 {REF} {Length: 3878} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}

Mlig455_023289 {REF} {Length: 239} {NoTransDecoderORF} {RNA1509_57501} {RNA1310_60087} {RNA815_63886}

Mlig455_023290 {REF} {Length: 660} {RNA1509_44389} {RNA1310_27455} {RNA815_10592}

Mlig455_030139 {REF} {Length: 465} {NoTransDecoderORF} {RNA1509_44389} {RNA1310_14765.2} {RNA815_7155}
44. MligTC455_42682 45 0.93 Mlig455_010400

Neo: -

Age: -

 0.956 - - - - 0.956 - Mlig455_010400 {REF} {Length: 1751} {NoTransDecoderORF} {RNA1509_58929} {RNA1310_128448} {RNA815_10390}
45. MligTC455_47868 5452 113.57 Mlig455_031216

Neo: -

Age: logFC(26M/2M)=-0.277

 TEKT1 0.956 - - - - 0.956 - Mlig455_031216 {REF} {Length: 1751} {TRANSSPLICED} {Pfam: Tektin family [PF03148.16, score=439.2]} {Human: ENSG00000167858, TEKT1, tektin 1, [RH, Score=379, Expect=4e-129]} {Mouse: ENSMUSG00000020799, Tekt1, tektin 1, [RH, Score=373, Expect=9e-127]} {Dmel: FBgn0052820, CG32820, [Score=217, Expect=4e-65]} {Smed: dd_Smed_v6_3287_0_2, dd_Smed_v6_3287_0_2, [RH, Score=448, Expect=1e-156]} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1310_15062.1, RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215} {RNA1509_1682, RNA1509_19187, RNA1509_25112, RNA1509_29996, RNA1509_52215, RNA815_6688}
46. MligTC455_50677 3742 77.95 Mlig455_024461

Neo: -

Age: -

 IQCD 0.956 - - - - 0.956 - Mlig455_024461 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1310_4220.1, RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931} {RNA1509_13541, RNA1509_17315, RNA1509_17777, RNA1509_1833, RNA1509_20931, RNA815_1223.1}
47. MligTC455_52083 972 20.26 Mlig455_009237, Mlig455_009643

Neo: -

Age: Up-Down-Up

Region-enriched R8: 2.031/0.00909

 FAT3 0.956 - - - - 0.956 -

Mlig455_009237 {REF} {Length: 9383} {Pfam: Cadherin domain [PF00028.19, score=291.4]; Laminin G domain [PF02210.26, score=96.4]; Cadherin cytoplasmic region [PF01049.19, score=79.9]; Laminin G domain [PF00054.25, score=77.7]; Cadherin-like [PF16184.7, score=57.2]; Cadherin-like [PF08266.14, score=20.1]} {Human: ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]; ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=286, Expect=3e-76]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=280, Expect=1e-74]; ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=279, Expect=3e-74]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=716, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=478, Expect=2e-135]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=175, Expect=4e-43]} {RNA1509_5439} {RNA1310_149} {RNA815_168}

Mlig455_009643 {REF} {Length: 9400} {Pfam: Cadherin domain [PF00028.19, score=300.2]; Laminin G domain [PF02210.26, score=97.0]; Cadherin cytoplasmic region [PF01049.19, score=80.9]; Laminin G domain [PF00054.25, score=78.3]; Cadherin-like [PF16184.7, score=54.5]; Cadherin-like [PF08266.14, score=22.1]} {Human: ENSG00000165323, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]; ENSG00000282908, FAT3, FAT atypical cadherin 3, [Score=280, Expect=2e-74]} {Mouse: ENSMUSG00000074505, Fat3, FAT atypical cadherin 3, [Score=275, Expect=3e-73]} {Dmel: FBgn0015609, CadN, Cadherin-N, [RH, Score=720, Expect=0.0]} {Celegans: WBGene00001980, hmr-1, Cadherin-related hmr-1, [RH, Score=468, Expect=2e-132]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=169, Expect=1e-41]} {RNA1509_5439} {RNA1310_149, RNA1509_5439} {RNA1509_5439, RNA815_168}
48. MligTC455_16167 177 3.69 Mlig455_065707

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.428

Region-enriched R2: 4.313/0.00011

 B3GALT5 0.955 - - - - 0.955 - Mlig455_065707 {REF} {Length: 4598} {Pfam: Galactosyltransferase [PF01762.23, score=160.3]} {Human: ENSG00000183778, B3GALT5, beta-1,3-galactosyltransferase 5, [RH, Score=130, Expect=2e-33]} {Mouse: ENSMUSG00000034780, B3galt1, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1, [Score=115, Expect=4e-28]; ENSMUSG00000074892, B3galt5, UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5, [Score=111, Expect=9e-27]} {Dmel: FBgn0035558, CG11357, [RH, Score=148, Expect=4e-39]} {Celegans: WBGene00000270, bre-5, Beta-1,3-galactosyltransferase bre-5, [Score=67.0, Expect=5e-12]} {Smed: dd_Smed_v6_12783_0_1, dd_Smed_v6_12783_0_1, [Score=152, Expect=6e-42]} {RNA1509_45540} {RNA1310_2435} {RNA815_25407}
49. MligTC455_16955 1687 35.15 Mlig455_051000

Neo: -

Age: Down-Up-Up

 PLA2G7 0.955 - - - - 0.955 - Mlig455_051000 {REF} {Length: 1559} {TRANSSPLICED} {Pfam: Platelet-activating factor acetylhydrolase, isoform II [PF03403.15, score=213.8]; alpha/beta hydrolase fold [PF00561.22, score=28.3]; Alpha/beta hydrolase family [PF12697.9, score=26.6]; Serine aminopeptidase, S33 [PF12146.10, score=25.3]; Chlorophyllase enzyme [PF12740.9, score=20.4]} {Human: ENSG00000146070, PLA2G7, phospholipase A2 group VII, [RH, Score=171, Expect=1e-48]} {Mouse: ENSMUSG00000037366, Pafah2, platelet-activating factor acetylhydrolase 2, [RH, Score=163, Expect=5e-46]; ENSMUSG00000023913, Pla2g7, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), [RH, Score=158, Expect=1e-43]} {Celegans: WBGene00003906, paf-1, PAF-1; PAF-acetylhydrolase, [RH, Score=142, Expect=2e-38]} {RNA1509_16678, RNA1509_21980} {RNA1310_21439.1, RNA1509_16678, RNA1509_21980} {RNA1509_16678, RNA1509_21980, RNA815_19873}
50. MligTC455_19430 476 9.92 Mlig455_059737

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.749

Region-enriched R2: 1.435/0.03961

 WDR49 0.955 - - - - 0.955 - Mlig455_059737 {REF} {Length: 4068} {Pfam: WD domain, G-beta repeat [PF00400.34, score=25.0]} {Human: ENSG00000174776, WDR49, WD repeat domain 49, [Score=140, Expect=3e-35]} {Mouse: ENSMUSG00000104301, Wdr49, WD repeat domain 49, [Score=130, Expect=1e-31]} {Smed: dd_Smed_v6_5437_0_2, dd_Smed_v6_5437_0_2, [Score=132, Expect=1e-32]} {RNA1509_29401, RNA1509_3708} {RNA1310_2384.2, RNA1509_29401} {RNA1509_29401, RNA815_724.1}
51. MligTC455_20201 1626 33.88 Mlig455_025333

Neo: -

Age: logFC(26M/2M)=-0.331

 TRPA1 0.955 - - - - 0.955 - Mlig455_025333 {REF} {Length: 5343} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=283.4]; Ankyrin repeat [PF00023.32, score=234.0]; Ankyrin repeats (many copies) [PF13637.8, score=227.4]; Ankyrin repeat [PF13606.8, score=217.2]; Ankyrin repeats (many copies) [PF13857.8, score=212.6]; Ion transport protein [PF00520.33, score=53.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=368, Expect=5e-107]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=363, Expect=2e-105]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=325, Expect=8e-92]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=2e-150]} {Smed: dd_Smed_v6_6201_0_1, dd_Smed_v6_6201_0_1, [RH, Score=754, Expect=0.0]} {RNA1509_20092} {RNA1310_1173, RNA1509_20092} {RNA1509_20092, RNA815_336}
52. MligTC455_34564 216 4.51 Mlig455_045027

Neo: -

Age: -

 VASH1 0.955 - - - - 0.955 - Mlig455_045027 {REF} {Length: 1457} {Pfam: Vasohibin [PF14822.8, score=320.1]} {Human: ENSG00000071246, VASH1, vasohibin 1, [RH, Score=258, Expect=2e-83]; ENSG00000143494, VASH2, vasohibin 2, [RH, Score=256, Expect=7e-83]} {Mouse: ENSMUSG00000021256, Vash1, vasohibin 1, [RH, Score=261, Expect=7e-85]; ENSMUSG00000037568, Vash2, vasohibin 2, [RH, Score=254, Expect=2e-82]} {Smed: dd_Smed_v6_12833_0_1, dd_Smed_v6_12833_0_1, [RH, Score=233, Expect=4e-75]} {RNA1509_59274} {RNA1310_23626.1} {RNA815_21188.1}
53. MligTC455_38148 787 16.4 Mlig455_067155

Neo: -

Age: -

 FAT1 0.955 - - - - 0.955 - Mlig455_067155 {REF} {Length: 4823} {Pfam: Cadherin domain [PF00028.19, score=183.7]; EGF-like domain [PF00008.29, score=55.8]; Calcium-binding EGF domain [PF07645.17, score=31.4]; Laminin G domain [PF02210.26, score=24.7]} {Human: ENSG00000083857, FAT1, FAT atypical cadherin 1, [Score=292, Expect=3e-79]} {Mouse: ENSMUSG00000070047, Fat1, FAT atypical cadherin 1, [Score=299, Expect=2e-81]} {Dmel: FBgn0261574, kug, kugelei, [Score=213, Expect=3e-55]} {Celegans: WBGene00000396, cdh-4, Cadherin-4, [Score=189, Expect=9e-48]} {Smed: dd_Smed_v6_7638_0_1, dd_Smed_v6_7638_0_1, [Score=218, Expect=1e-56]} {RNA1509_13557} {RNA1310_1912.1} {RNA815_14235}
54. MligTC455_45835 2142 44.62 Mlig455_031421, Mlig455_056470

Neo: -

Age: -

 MAPK15 0.955 - - - - 0.955 -

Mlig455_031421 {REF} {Length: 3734} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.8]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=482, Expect=1e-163]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=475, Expect=4e-161]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=431, Expect=2e-139]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=2e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=535, Expect=0.0]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}

Mlig455_056470 {REF} {Length: 4231} {Pfam: Protein kinase domain [PF00069.27, score=229.3]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=114.3]} {Human: ENSG00000274205, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]; ENSG00000181085, MAPK15, mitogen-activated protein kinase 15, [RH, Score=480, Expect=3e-162]} {Mouse: ENSMUSG00000063704, Mapk15, mitogen-activated protein kinase 15, [RH, Score=474, Expect=7e-160]} {Dmel: FBgn0052703, Erk7, Extracellularly regulated kinase 7, [RH, Score=430, Expect=2e-138]} {Celegans: WBGene00015478, mapk-15, Putative serine/threonine-protein kinase C05D10.2, [RH, Score=498, Expect=5e-171]} {Smed: dd_Smed_v6_11396_0_1, dd_Smed_v6_11396_0_1, [RH, Score=534, Expect=1e-179]} {RNA1509_9258} {RNA1310_16008} {RNA815_26216}
55. MligTC455_06793 33 0.68 Mlig455_037577

Neo: -

Age: -

 0.954 - - - - 0.954 - Mlig455_037577 {REF} {Length: 735} {RNA1509_2515} {RNA1310_11307} {RNA815_3258.1}
56. MligTC455_50676 3764 78.41 Mlig455_024344

Neo: -

Age: -

 IQCD 0.954 - - - - 0.954 - Mlig455_024344 {REF} {Length: 1834} {TRANSSPLICED} {Pfam: IQ calmodulin-binding motif [PF00612.29, score=23.1]; Protein of unknown function (DUF3584) [PF12128.10, score=18.7]} {Human: ENSG00000166578, IQCD, IQ motif containing D, [RH, Score=225, Expect=3e-68]} {Mouse: ENSMUSG00000029601, Iqcd, IQ motif containing D, [RH, Score=204, Expect=3e-60]} {Dmel: FBgn0033705, CG13168, [Score=47.8, Expect=1e-05]} {Smed: dd_Smed_v6_7079_0_1, dd_Smed_v6_7079_0_1, [RH, Score=296, Expect=2e-95]} {RNA1509_1833, RNA1509_46413} {RNA1310_4220.1, RNA1509_46413} {RNA1509_46413, RNA815_1223.1}
57. MligTC455_21558 31 0.64 Mlig455_048987

Neo: -

Age: -

 0.953 - - - - 0.953 - Mlig455_048987 {REF} {Length: 5660} {Pfam: Helix-turn-helix domain [PF13936.8, score=20.7]; Helix-turn-helix domain [PF18024.3, score=20.4]; Homeodomain-like domain [PF13384.8, score=19.4]} {RNA1509_2515} {RNA1310_11002} {RNA815_3258.1}
58. MligTC455_28168 822 17.12 Mlig455_023828

Neo: -

Age: -

 0.953 - - - - 0.953 - Mlig455_023828 {REF} {Length: 3967} {Smed: dd_Smed_v6_6429_0_1, dd_Smed_v6_6429_0_1, [Score=99.0, Expect=5e-22]} {RNA1509_9848} {RNA1310_8221} {RNA815_6368.1}
59. MligTC455_31291 845 17.6 Mlig455_013887, Mlig455_057722

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.442

Region-enriched R8: 1.865/0.01323

 GRIA2 0.953 - - - - 0.953 -

Mlig455_013887 {REF} {Length: 2798} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=81.4]; Ligand-gated ion channel [PF00060.28, score=67.6]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=62.5]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=178, Expect=5e-47]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=177, Expect=1e-46]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=173, Expect=3e-45]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=178, Expect=4e-47]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=177, Expect=8e-47]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=173, Expect=2e-45]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=2e-41]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=156, Expect=4e-40]} {Smed: dd_Smed_v6_14655_0_1, dd_Smed_v6_14655_0_1, [Score=171, Expect=4e-45]} {RNA1509_15014} {RNA1310_5818.1} {RNA815_1723}

Mlig455_057722 {REF} {Length: 3577} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=77.9]; Ligand-gated ion channel [PF00060.28, score=65.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=61.7]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=177, Expect=2e-45]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=176, Expect=4e-45]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=172, Expect=9e-44]} {Mouse: ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=177, Expect=2e-45]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=175, Expect=5e-45]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=172, Expect=6e-44]} {Dmel: FBgn0039927, CG11155, [Score=161, Expect=1e-40]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=154, Expect=2e-38]} {Smed: dd_Smed_v6_22973_0_1, dd_Smed_v6_22973_0_1, [Score=176, Expect=1e-45]} {RNA1509_15014} {RNA1310_5818.1, RNA1509_15014} {RNA1509_15014, RNA815_1723}
60. MligTC455_33995 174 3.63 Mlig455_042151

Neo: -

Age: logFC(26M/2M)=-0.705

 ANK1 0.953 - - - - 0.953 - Mlig455_042151 {REF} {Length: 8174} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=414.4]; Ankyrin repeats (many copies) [PF13637.8, score=253.9]; Ankyrin repeats (many copies) [PF13857.8, score=156.9]; Ankyrin repeat [PF13606.8, score=149.6]; Ankyrin repeat [PF00023.32, score=87.1]; Family of unknown function (DUF6189) [PF19688.1, score=71.1]; 3,4-dihydroxy-2-butanone 4-phosphate synthase [PF00926.21, score=44.8]; Domain of unknown function (DUF6487) [PF20097.1, score=28.5]} {Human: ENSG00000029534, ANK1, ankyrin 1, [Score=81.6, Expect=1e-14]} {Mouse: ENSMUSG00000031543, Ank1, ankyrin 1, erythroid, [Score=71.6, Expect=9e-12]; ENSMUSG00000014498, Ankrd52, ankyrin repeat domain 52, [Score=68.2, Expect=9e-11]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=65.5, Expect=4e-10]} {RNA1509_28890} {RNA1310_16696.1, RNA1509_28890} {RNA1509_28890, RNA815_12859.1}
61. MligTC455_40435 2578 53.71 Mlig455_007622

Neo: -

Age: logFC(26M/2M)=-0.289

 0.953 - - - - 0.953 - Mlig455_007622 {REF} {Length: 3294} {Pfam: Fasciclin domain [PF02469.24, score=128.8]} {Dmel: FBgn0260745, mfas, midline fasciclin, [Score=51.6, Expect=2e-06]} {Celegans: WBGene00009162, F26E4.7, [RH, Score=70.1, Expect=3e-12]} {RNA1509_14388, RNA1509_37320, RNA1509_7509} {RNA1310_4612.1, RNA1509_14388, RNA1509_37320} {RNA1509_14388, RNA1509_37320, RNA815_1343.1}
62. MligTC455_41827 60 1.24 Mlig455_044807

Neo: -

Age: Down-Up-Down

Region-enriched R2: 3.953/0.02767

 0.953 - - - - 0.953 - Mlig455_044807 {REF} {Length: 4395} {Dmel: FBgn0264693, ens, ensconsin, [Score=68.2, Expect=2e-11]} {Smed: dd_Smed_v6_5361_0_1, dd_Smed_v6_5361_0_1, [RH, Score=65.1, Expect=1e-10]} {RNA1509_19058} {RNA1310_6742.2} {RNA815_12863}
63. MligTC455_45179 4166 86.78 Mlig455_048432

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.401

 CFAP20 0.953 - - - - 0.953 - Mlig455_048432 {REF} {Length: 1648} {Pfam: Protein of unknown function (DUF667) [PF05018.15, score=310.7]} {Human: ENSG00000070761, CFAP20, cilia and flagella associated protein 20, [RH, Score=367, Expect=4e-131]} {Mouse: ENSMUSG00000031796, Cfap20, cilia and flagella associated protein 20, [RH, Score=370, Expect=2e-132]} {Dmel: FBgn0032248, Bug22, Basal body up regulated gene 22, [RH, Score=368, Expect=9e-132]} {Celegans: WBGene00008288, C54C6.6, Cilia- and flagella-associated protein 20, [RH, Score=345, Expect=1e-122]} {Smed: dd_Smed_v6_4843_0_1, dd_Smed_v6_4843_0_1, [RH, Score=362, Expect=2e-129]} {RNA1509_1898} {RNA1310_20376.1} {RNA815_8129.1}
64. MligTC455_52356 37 0.76 Mlig455_042513

Neo: -

Age: -

 0.953 - - - - 0.953 - Mlig455_042513 {REF} {Length: 755} {NoTransDecoderORF}
65. MligTC455_52942 1583 32.98 Mlig455_016027

Neo: -

Age: Down-Up-Down

 PNPT1 0.953 - - - - 0.953 - Mlig455_016027 {REF} {Length: 2518} {Pfam: Ligand-gated ion channel [PF00060.28, score=20.1]} {Human: ENSG00000138035, PNPT1, polyribonucleotide nucleotidyltransferase 1, [RH, Score=53.1, Expect=3e-07]} {Mouse: ENSMUSG00000020464, Pnpt1, polyribonucleotide nucleotidyltransferase 1, [RH, Score=54.7, Expect=5e-08]} {Smed: dd_Smed_v6_8233_0_1, dd_Smed_v6_8233_0_1, [Score=47.4, Expect=6e-06]} {RNA1509_45927} {RNA1310_3249} {RNA815_1535.1}
66. MligTC455_27609 231 4.8 Mlig455_031171

Neo: -

Age: Up-Down-Down

 RYR2 0.952 - - - - 0.952 - Mlig455_031171 {REF} {Length: 1840} {Human: ENSG00000198626, RYR2, ryanodine receptor 2, [Score=57.0, Expect=9e-10]; ENSG00000198838, RYR3, ryanodine receptor 3, [Score=55.8, Expect=2e-09]; ENSG00000196218, RYR1, ryanodine receptor 1, [Score=55.1, Expect=4e-09]} {Mouse: ENSMUSG00000021313, Ryr2, ryanodine receptor 2, cardiac, [Score=57.0, Expect=6e-10]; ENSMUSG00000057378, Ryr3, ryanodine receptor 3, [Score=56.2, Expect=1e-09]; ENSMUSG00000030592, Ryr1, ryanodine receptor 1, skeletal muscle, [Score=55.1, Expect=3e-09]} {Dmel: FBgn0011286, RyR, Ryanodine receptor, [Score=52.8, Expect=1e-08]} {Smed: dd_Smed_v6_3814_1_1, dd_Smed_v6_3814_1_1, [Score=99.4, Expect=4e-25]} {RNA1509_17046} {RNA1310_1857} {RNA815_62.1}
67. MligTC455_30865 559 11.65 Mlig455_050410

Neo: -

Age: logFC(26M/2M)=-0.223

 0.952 - - - - 0.952 - Mlig455_050410 {REF} {Length: 2602} {TRANSSPLICED} {RNA1509_18063} {RNA1310_7936.1, RNA1509_18063} {RNA1509_18063, RNA815_2370.1}
68. MligTC455_31427 429 8.94 Mlig455_024101

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.449

 CHRNA3 0.952 - - - - 0.952 - Mlig455_024101 {REF} {Length: 2557} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=242.5]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=210.4]} {Human: ENSG00000080644, CHRNA3, cholinergic receptor nicotinic alpha 3 subunit, [Score=395, Expect=3e-131]; ENSG00000101204, CHRNA4, cholinergic receptor nicotinic alpha 4 subunit, [Score=377, Expect=1e-122]} {Mouse: ENSMUSG00000027577, Chrna4, cholinergic receptor, nicotinic, alpha polypeptide 4, [Score=372, Expect=8e-121]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=363, Expect=2e-119]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=355, Expect=4e-116]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=443, Expect=2e-149]} {Celegans: WBGene00006797, unc-63, Acetylcholine receptor subunit alpha-type unc-63, [Score=387, Expect=2e-128]} {Smed: dd_Smed_v6_9799_0_1, dd_Smed_v6_9799_0_1, [Score=382, Expect=2e-126]} {RNA1509_19028} {RNA1310_8041, RNA1509_19028} {RNA1509_19028, RNA815_11178}
69. MligTC455_36816 362 7.54 Mlig455_027841, Mlig455_060008

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.712

 ANK3 0.952 - - - - 0.952 -

Mlig455_027841 {REF} {Length: 5725} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=91.6]; Protein of unknown function (DUF3421) [PF11901.10, score=84.7]; Ankyrin repeats (many copies) [PF13637.8, score=72.1]; Ankyrin repeats (many copies) [PF13857.8, score=49.2]; Ankyrin repeat [PF13606.8, score=41.0]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=55.5, Expect=1e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=62.4, Expect=5e-09]} {Dmel: FBgn0034583, CG10527, [Score=93.6, Expect=3e-20]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=81.3, Expect=5e-15]} {Smed: dd_Smed_v6_766_0_1, dd_Smed_v6_766_0_1, [Score=118, Expect=2e-30]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}

Mlig455_060008 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=93.3]; Ankyrin repeats (many copies) [PF13637.8, score=74.1]; Ankyrin repeats (many copies) [PF13857.8, score=51.3]; Ankyrin repeat [PF13606.8, score=43.0]; Ankyrin repeat [PF00023.32, score=19.4]} {Human: ENSG00000151150, ANK3, ankyrin 3, [Score=53.5, Expect=3e-06]} {Mouse: ENSMUSG00000052331, Ankrd44, ankyrin repeat domain 44, [Score=61.2, Expect=8e-09]} {Dmel: FBgn0016920, nompC, no mechanoreceptor potential C, [Score=52.0, Expect=5e-06]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=80.5, Expect=8e-15]} {Smed: dd_Smed_v6_13721_0_1, dd_Smed_v6_13721_0_1, [Score=59.3, Expect=1e-08]} {RNA1509_30268} {RNA1310_2381} {RNA815_861}
70. MligTC455_46649 100 2.09 Mlig455_023901

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.216/0.00086

 SLC46A2 0.952 - - - - 0.952 - Mlig455_023901 {REF} {Length: 2695} {Pfam: Major Facilitator Superfamily [PF07690.18, score=79.0]} {Human: ENSG00000119457, SLC46A2, solute carrier family 46 member 2, [Score=71.6, Expect=1e-12]} {Mouse: ENSMUSG00000029650, Slc46a3, solute carrier family 46, member 3, [Score=77.4, Expect=1e-14]} {Dmel: FBgn0030576, CG15890, [RH, Score=100, Expect=5e-22]} {Celegans: WBGene00016705, C46C11.2, [RH, Score=95.9, Expect=6e-21]} {Smed: dd_Smed_v6_10822_0_1, dd_Smed_v6_10822_0_1, [Score=344, Expect=1e-113]} {RNA1509_40290} {RNA1310_13436} {RNA815_19265}
71. MligTC455_48507 330 6.88 Mlig455_030151

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.466

 TMEM232 0.952 - - - - 0.952 - Mlig455_030151 {REF} {Length: 2337} {TRANSSPLICED} {Pfam: Transmembrane protein family 232 [PF15877.7, score=221.6]} {Human: ENSG00000186952, TMEM232, transmembrane protein 232, [Score=155, Expect=2e-39]} {Mouse: ENSMUSG00000045036, Tmem232, transmembrane protein 232, [Score=164, Expect=2e-42]} {Smed: dd_Smed_v6_15138_0_1, dd_Smed_v6_15138_0_1, [RH, Score=160, Expect=8e-42]} {RNA1509_11088} {RNA1310_8942.1} {RNA815_6522}
72. MligTC455_50684 144 3.01 Mlig455_008825

Neo: -

Age: Up-Down-Down

 0.952 - - - - 0.952 - Mlig455_008825 {REF} {Length: 1594} {RNA1509_24338} {RNA1310_77.2} {RNA815_489}
73. MligTC455_22412 271 5.65 Mlig455_057681, Mlig455_059990

Neo: -

Age: Down-Up-Up

 0.951 - - - - 0.951 -

Mlig455_057681 {REF} {Length: 2023} {RNA1509_30929} {RNA1310_27672} {RNA815_26534}

Mlig455_059990 {REF} {Length: 2023} {RNA1509_30929} {RNA1310_27672} {RNA815_26534}
74. MligTC455_28794 33 0.68 Mlig455_043620, Mlig455_043652

Neo: Irradiation

Age: Up-Down-Down

 0.951 - - - - 0.951 -

Mlig455_043620 {REF} {Length: 1703} {Pfam: Tetraspanin family [PF00335.22, score=51.7]} {Smed: dd_Smed_v6_1719_0_2, dd_Smed_v6_1719_0_2, [Score=50.8, Expect=4e-07]} {RNA1509_14599} {RNA1310_20055.2} {RNA815_15207}

Mlig455_043652 {REF} {Length: 915} {TRANSSPLICED} {Pfam: Tetraspanin family [PF00335.22, score=49.3]} {Smed: dd_Smed_v6_1719_0_2, dd_Smed_v6_1719_0_2, [Score=48.5, Expect=6e-07]} {RNA1509_14599} {RNA1310_20055.2} {RNA815_15207}
75. MligTC455_29451 819 17.07 Mlig455_026453

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.590

 LMNTD1 0.951 - - - - 0.951 - Mlig455_026453 {REF} {Length: 3415} {Pfam: Intermediate filament protein [PF00038.23, score=53.0]; Lamin Tail Domain [PF00932.21, score=40.2]; Mechanosensitive ion channel porin domain [PF12795.9, score=18.4]} {Human: ENSG00000152936, LMNTD1, lamin tail domain containing 1, [RH, Score=148, Expect=6e-38]} {Mouse: ENSMUSG00000054966, Lmntd1, lamin tail domain containing 1, [RH, Score=140, Expect=2e-35]} {Dmel: FBgn0002525, Lam, Lamin, [Score=72.4, Expect=1e-12]} {Celegans: WBGene00002051, ifa-3, Intermediate filament protein ifa-3, [Score=62.0, Expect=1e-09]} {Smed: dd_Smed_v6_10248_0_1, dd_Smed_v6_10248_0_1, [RH, Score=405, Expect=7e-127]} {RNA1509_7063} {RNA1310_3989.1} {RNA815_1147.1}
76. MligTC455_51902 1049 21.85 Mlig455_021705

Neo: -

Age: logFC(26M/2M)=-0.488

 CHRNB3 0.951 - - - - 0.951 - Mlig455_021705 {REF} {Length: 1861} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=147.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=72.7]} {Human: ENSG00000147432, CHRNB3, cholinergic receptor nicotinic beta 3 subunit, [Score=191, Expect=2e-55]; ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=189, Expect=2e-54]; ENSG00000169684, CHRNA5, cholinergic receptor nicotinic alpha 5 subunit, [Score=182, Expect=6e-52]} {Mouse: ENSMUSG00000031492, Chrnb3, cholinergic receptor, nicotinic, beta polypeptide 3, [Score=186, Expect=2e-53]; ENSMUSG00000035594, Chrna5, cholinergic receptor, nicotinic, alpha polypeptide 5, [Score=185, Expect=2e-53]; ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=182, Expect=4e-52]} {Dmel: FBgn0000036, nAChRalpha1, nicotinic Acetylcholine Receptor alpha1, [Score=177, Expect=2e-49]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=174, Expect=7e-49]} {Smed: dd_Smed_v6_2019_0_1, dd_Smed_v6_2019_0_1, [Score=347, Expect=6e-116]} {RNA1509_8724} {RNA1310_17144.1} {RNA815_6285}
77. MligTC455_53211 1358 28.3 Mlig455_040065, Mlig455_040091

Neo: -

Age: logFC(26M/2M)=-0.362

Region-enriched R4: 1.888/0.01442

 0.95 - - - - 0.950 -

Mlig455_040065 {REF} {Length: 3189} {RNA1509_49542, RNA1509_9168} {RNA1310_8796.1, RNA1509_49542, RNA1509_9168} {RNA1509_49542, RNA1509_9168, RNA815_3100}

Mlig455_040091 {REF} {Length: 2759} {RNA1509_39791, RNA1509_9168} {RNA1310_8796.1, RNA1509_39791} {RNA1509_39791, RNA815_3100}

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