Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_19231 | 149 | 3.11 | Mlig455_064092 | Neo: - Age: - Region-enriched R7: 4.202/0.00037 |
Mlig455_064092 {REF} {Length: 1757} {RNA1509_35166} {RNA1310_79280} {RNA815_45488} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -5.978 | 2.074 | 0.99966 | 1.00000 | |
RegionR2 | 1.297 | 2.074 | 0.34914 | 0.74270 | |
RegionR3 | 1.134 | 2.074 | 0.35466 | 0.89001 | |
RegionR4 | -0.681 | 2.074 | 0.89407 | 1.00000 | |
RegionR5 | 0.709 | 2.074 | 0.51836 | 0.88114 | |
RegionR6 | 3.7 | 2.074 | 0.00011 | 0.00828 | |
RegionR7 | 4.202 | 2.074 | 0.00000 | 0.00037 | |
RegionR8 | -4.381 | 2.074 | 1.00000 | 1.00000 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 0.705 | 2.074 | 0.99995 | 1.00000 | |
RegenerationR2 | 0.908 | 2.074 | 0.29442 | 0.73672 | |
RegenerationR3 | 1.479 | 2.074 | 0.11297 | 0.52664 | |
RegenerationR4 | 1.867 | 2.074 | 0.05048 | 0.36151 | |
RegenerationR5 | 1.622 | 2.074 | 0.05903 | 0.38705 | |
RegenerationR6 | -0.931 | 2.074 | 0.24414 | 0.59213 | |
RegenerationBL | 1.463 | 2.074 | 0.32674 | 0.69328 | |
RegenerationTP | 3.769 | 2.074 | 0.02087 | 0.24715 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_19231 | 149 | 3.11 | Mlig455_064092 | Neo: - Age: - Region-enriched R7: 4.202/0.00037 |
6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_064092 {REF} {Length: 1757} {RNA1509_35166} {RNA1310_79280} {RNA815_45488} | |
2. | MligTC455_53341 | 1321 | 27.52 | Mlig455_026459, Mlig455_044751 | Neo: - Age: - Region-enriched R7: 7.097/0.00000 Regeneration-downregulated BL: -10.182 Regeneration-depleted BL: -10.182 |
3.355 | 0.809 | 0.962 | 0.781 | - | 0.803 | - | Mlig455_026459 {REF} {Length: 739} {RNA1509_35464} {RNA1310_60456.2} {RNA815_44529} Mlig455_044751 {REF} {Length: 902} {RNA1509_35464} {RNA1310_60456.2, RNA1509_35464} {RNA1509_35464, RNA815_44529} |
|
3. | MligTC455_39782 | 128 | 2.66 | Mlig455_010278 | Neo: - Age: - Region-enriched R7: 6.391/0.00442 |
NOTCH3 | 3.183 | 0.701 | 0.966 | 0.810 | - | 0.706 | - | Mlig455_010278 {REF} {Length: 3985} {Pfam: EGF-like domain [PF00008.29, score=132.7]; Calcium-binding EGF domain [PF07645.17, score=118.5]; Delta serrate ligand [PF01414.21, score=71.5]; Human growth factor-like EGF [PF12661.9, score=69.6]; EGF domain [PF12947.9, score=27.7]; Complement Clr-like EGF-like [PF12662.9, score=25.5]; EGF-like domain [PF07974.15, score=19.2]} {Human: ENSG00000074181, NOTCH3, notch 3, [Score=157, Expect=4e-38]; ENSG00000101384, JAG1, jagged 1, [Score=152, Expect=8e-37]} {Mouse: ENSMUSG00000027878, Notch2, notch 2, [Score=150, Expect=5e-36]; ENSMUSG00000027276, Jag1, jagged 1, [Score=149, Expect=8e-36]} {Dmel: FBgn0004647, N, Notch, [Score=140, Expect=3e-33]} {Celegans: WBGene00018547, clec-78, C-type LECtin, [Score=139, Expect=8e-33]} {Smed: dd_Smed_v6_7067_0_1, dd_Smed_v6_7067_0_1, [Score=134, Expect=2e-31]} {RNA1310_15133} {RNA815_29197} |
4. | MligTC455_53340 | 109 | 2.26 | Mlig455_026428 | Neo: - Age: - Region-enriched R7: 5.655/0.00005 |
2.702 | - | 0.955 | 0.924 | - | 0.823 | - | Mlig455_026428 {REF} {Length: 660} {RNA1509_35464} {RNA1310_60456.1} {RNA815_44529} | |
5. | MligTC455_22736 | 174 | 3.62 | Mlig455_036576 | Neo: - Age: - Region-enriched R6: 5.263/0.00000 Regeneration-depleted R6: -8.651 |
PHEX | 2.656 | 0.781 | 0.910 | 0.965 | - | - | - | Mlig455_036576 {REF} {Length: 3336} {Pfam: Peptidase family M13 [PF01431.23, score=134.4]; Peptidase family M13 [PF05649.15, score=87.9]} {Human: ENSG00000102174, PHEX, phosphate regulating endopeptidase homolog X-linked, [Score=155, Expect=1e-38]; ENSG00000284917, EEF1AKMT4-ECE2, EEF1AKMT4-ECE2 readthrough, [Score=154, Expect=3e-38]; ENSG00000145194, ECE2, endothelin converting enzyme 2, [Score=154, Expect=2e-38]; ENSG00000196549, MME, membrane metalloendopeptidase, [Score=148, Expect=2e-36]} {Mouse: ENSMUSG00000022842, Ece2, endothelin converting enzyme 2, [Score=152, Expect=6e-38]; ENSMUSG00000115293, Gm49333, predicted gene, 49333, [Score=152, Expect=8e-38]; ENSMUSG00000027820, Mme, membrane metallo endopeptidase, [Score=148, Expect=1e-36]; ENSMUSG00000057457, Phex, phosphate regulating endopeptidase homolog, X-linked, [Score=146, Expect=6e-36]} {Dmel: FBgn0031081, Nep3, Neprilysin 3, [Score=135, Expect=2e-32]} {Celegans: WBGene00013926, nep-1, Neprilysin-1, [Score=155, Expect=4e-39]} {Smed: dd_Smed_v6_8276_0_1, dd_Smed_v6_8276_0_1, [Score=149, Expect=3e-37]} {RNA1509_47798} {RNA1310_6773, RNA1509_47798} {RNA1509_47798, RNA815_4414} |
6. | MligTC455_10855 | 592 | 12.33 | Mlig455_039847 | Neo: - Age: Down-Down-Up Region-enriched R7: 5.970/0.00000 |
CYP7B1 | 2.483 | - | 0.784 | 0.971 | - | - | 0.728 | Mlig455_039847 {REF} {Length: 2444} {Pfam: Cytochrome P450 [PF00067.24, score=121.0]} {Human: ENSG00000172817, CYP7B1, cytochrome P450 family 7 subfamily B member 1, [RH, Score=128, Expect=3e-31]} {Mouse: ENSMUSG00000017969, Ptgis, prostaglandin I2 (prostacyclin) synthase, [Score=121, Expect=5e-29]} {Dmel: FBgn0038037, Cyp9f2, [Score=70.1, Expect=2e-12]} {Celegans: WBGene00010354, cyp-31A2, CYtochrome P450 family, [Score=49.3, Expect=4e-06]} {Smed: dd_Smed_v6_4319_0_1, dd_Smed_v6_4319_0_1, [Score=71.2, Expect=4e-13]} {RNA1509_19584} {RNA1310_11331.1, RNA1509_19584} {RNA1509_19584, RNA815_3881.1} |
7. | MligTC455_17459 | 105 | 2.19 | Mlig455_040226 | Neo: - Age: - Region-enriched R7: 6.273/0.00000 |
ZNF407 | 1.816 | - | 0.973 | - | - | 0.843 | - | Mlig455_040226 {REF} {Length: 3774} {Pfam: Serine rich protein interaction domain [PF08824.12, score=62.9]; Zinc-finger double domain [PF13465.8, score=44.5]; Variant SH3 domain [PF14604.8, score=32.6]; Variant SH3 domain [PF07653.19, score=26.7]; SH3 domain [PF00018.30, score=26.3]; Zinc finger, C2H2 type [PF00096.28, score=23.9]} {Human: ENSG00000215421, ZNF407, zinc finger protein 407, [Score=75.5, Expect=2e-15]; ENSG00000269693, AC010422.6, novel transcript, [Score=74.7, Expect=6e-15]; ENSG00000130684, ZNF337, zinc finger protein 337, [Score=74.3, Expect=7e-13]; ENSG00000197024, ZNF398, zinc finger protein 398, [Score=73.9, Expect=7e-13]; ENSG00000163795, ZNF513, zinc finger protein 513, [Score=73.9, Expect=5e-13]; ENSG00000189420, ZFP92, ZFP92 zinc finger protein, [Score=73.6, Expect=5e-13]; ENSG00000050820, BCAR1, BCAR1, Cas family scaffold protein, [Score=73.6, Expect=1e-12]; ENSG00000285460, BCAR1, BCAR1, Cas family scaffold protein, [Score=73.6, Expect=1e-12]} {Mouse: ENSMUSG00000029249, Rest, RE1-silencing transcription factor, [Score=77.8, Expect=4e-14]; ENSMUSG00000062519, Zfp398, zinc finger protein 398, [Score=76.3, Expect=9e-14]; ENSMUSG00000043059, Zfp513, zinc finger protein 513, [Score=74.7, Expect=2e-13]} {Dmel: FBgn0001180, hb, hunchback, [Score=174, Expect=8e-45]} {Celegans: WBGene00001824, hbl-1, Hunchback-like protein, [Score=147, Expect=6e-36]} {Smed: dd_Smed_v6_5127_0_2, dd_Smed_v6_5127_0_2, [Score=152, Expect=3e-39]} {RNA1509_32281} {RNA1310_16095} {RNA815_7228} |
8. | MligTC455_45581 | 49 | 1.03 | Mlig455_045128, Mlig455_045162 | Neo: - Age: Down-Down-Up Region-enriched R7: 4.346/0.00514 |
1.814 | - | 0.973 | 0.841 | - | - | - | Mlig455_045128 {REF} {Length: 2950} {RNA1509_29, RNA1509_3187} {RNA1310_4199.2, RNA1509_3187} {RNA1509_3187, RNA815_8541.1} Mlig455_045162 {REF} {Length: 620} {NoTransDecoderORF} {RNA1509_10639} {RNA1310_4199.2} {RNA815_24585} |
|
9. | MligTC455_43448 | 71 | 1.49 | Mlig455_003393 | Neo: - Age: - |
1.736 | 0.786 | - | - | - | - | 0.950 | Mlig455_003393 {REF} {Length: 1919} {NoTransDecoderORF} {RNA1509_1651} {RNA1310_75407} {RNA815_43971} | |
10. | MligTC455_41483 | 50 | 1.05 | Mlig455_006754 | Neo: - Age: - |
1.724 | - | - | - | - | 0.953 | 0.771 | Mlig455_006754 {REF} {Length: 3493} {RNA1310_64559} {RNA815_57833} | |
11. | MligTC455_28550 | 147 | 3.06 | Mlig455_048750 | Neo: - Age: logFC(26M/2M)=1.038 Region-enriched R5: 2.521/0.03072 |
NDRG1 | 0.984 | - | - | - | - | 0.984 | - | Mlig455_048750 {REF} {Length: 2415} {TRANSSPLICED} {Pfam: Ndr family [PF03096.16, score=186.2]} {Human: ENSG00000104419, NDRG1, N-myc downstream regulated 1, [Score=125, Expect=9e-32]; ENSG00000101079, NDRG3, NDRG family member 3, [Score=122, Expect=1e-30]} {Mouse: ENSMUSG00000027634, Ndrg3, N-myc downstream regulated gene 3, [Score=119, Expect=1e-29]; ENSMUSG00000005125, Ndrg1, N-myc downstream regulated gene 1, [Score=118, Expect=3e-29]} {Dmel: FBgn0043070, MESK2, Misexpression suppressor of KSR 2, [Score=127, Expect=2e-32]} {Celegans: WBGene00013020, Y48G10A.3, [RH, Score=117, Expect=1e-29]} {Smed: dd_Smed_v6_1911_0_1, dd_Smed_v6_1911_0_1, [Score=226, Expect=2e-70]} {RNA1509_13688} {RNA1310_24392} {RNA815_9919} |
12. | MligTC455_52439 | 266 | 5.53 | Mlig455_065368 | Neo: - Age: logFC(26M/2M)=-0.267 |
0.974 | - | - | - | - | 0.974 | - | Mlig455_065368 {REF} {Length: 2661} {TRANSSPLICED} {RNA1509_22620} {RNA1310_9393.1, RNA1509_22620} {RNA1509_22620, RNA815_16638} | |
13. | MligTC455_20722 | 36 | 0.74 | Mlig455_001696, Mlig455_066078, Mlig455_066120 | Neo: - Age: - |
0.97 | - | 0.970 | - | - | - | - | Mlig455_001696 {REF} {Length: 1535} {RNA1310_134737} {RNA815_57224} Mlig455_066078 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=20.4]} {RNA1310_134737} {RNA815_57224} Mlig455_066120 {REF} {Length: 1438} {Pfam: Glycine rich protein [PF12810.9, score=25.9]} {RNA1310_134737} {RNA815_57224} |
|
14. | MligTC455_47479 | 94 | 1.96 | Mlig455_001396 | Neo: - Age: Down-Up-Up |
TRAF4 | 0.96 | - | - | - | - | - | 0.960 | Mlig455_001396 {REF} {Length: 1682} {Human: ENSG00000076604, TRAF4, TNF receptor associated factor 4, [Score=91.7, Expect=2e-20]} {Mouse: ENSMUSG00000017386, Traf4, TNF receptor associated factor 4, [Score=92.4, Expect=6e-21]} {Celegans: WBGene00006612, trf-1, TNF Receptor Associated Factor (TRAF) homolog; TRF-1, [Score=108, Expect=5e-27]} {Smed: dd_Smed_v6_13517_0_1, dd_Smed_v6_13517_0_1, [Score=146, Expect=2e-40]} {RNA1310_27902.1} {RNA815_12300} |
15. | MligTC455_50221 | 219 | 4.56 | Mlig455_028545 | Neo: - Age: - Region-enriched R5: 2.000/0.01742 |
NEURL2 | 0.958 | - | - | - | 0.958 | - | - | Mlig455_028545 {REF} {Length: 1529} {TRANSSPLICED} {Pfam: Neuralized [PF07177.14, score=107.5]} {Human: ENSG00000124257, NEURL2, neuralized E3 ubiquitin protein ligase 2, [RH, Score=127, Expect=1e-34]} {Mouse: ENSMUSG00000039873, Neurl2, neuralized E3 ubiquitin protein ligase 2, [RH, Score=130, Expect=7e-36]} {Dmel: FBgn0035059, CG3894, [RH, Score=148, Expect=1e-42]} {Smed: dd_Smed_v6_10431_0_1, dd_Smed_v6_10431_0_1, [Score=54.3, Expect=3e-08]} {RNA1509_33355} {RNA1310_21592.1} {RNA815_15057} |
16. | MligTC455_50540 | 5116 | 106.59 | Mlig455_068057 | Neo: - |
0.954 | - | - | - | - | 0.954 | - | Mlig455_068057 {REF} {Length: 521} {TRANSSPLICED} {Pfam: Family of unknown function (DUF5564) [PF17719.3, score=35.5]} {Mouse: ENSMUSG00000071653, 1810009A15Rik, RIKEN cDNA 1810009A15 gene, [Score=42.7, Expect=7e-06]} {RNA1509_23900, RNA1509_3995} {RNA1310_64510.1, RNA1509_23900, RNA1509_3995} {RNA1509_23900, RNA1509_3995, RNA815_30472} | |
17. | MligTC455_35022 | 166 | 3.45 | Mlig455_007549 | Neo: - Age: logFC(26M/2M)=1.108 |
NDUFA2 | 0.953 | - | - | - | - | 0.953 | - | Mlig455_007549 {REF} {Length: 645} {TRANSSPLICED} {Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain [PF05047.18, score=49.8]} {Human: ENSG00000131495, NDUFA2, NADH:ubiquinone oxidoreductase subunit A2, [RH, Score=97.1, Expect=2e-27]} {Mouse: ENSMUSG00000014294, Ndufa2, NADH:ubiquinone oxidoreductase subunit A2, [RH, Score=94.7, Expect=1e-26]} {Dmel: FBgn0040705, ND-B8, NADH dehydrogenase (ubiquinone) B8 subunit, [RH, Score=68.6, Expect=2e-16]} {Celegans: WBGene00013406, Y63D3A.7, [RH, Score=88.2, Expect=2e-24]} {Smed: dd_Smed_v6_1815_0_1, dd_Smed_v6_1815_0_1, [RH, Score=87.4, Expect=3e-24]} {RNA1509_16031} {RNA1310_56837.1} {RNA815_28457} |