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Results for MligTC455_31128

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_31128 677 14.09 Mlig455_014434, Mlig455_014442

Neo: -

Age: Down-Down-Up

LIG4

Mlig455_014434 {REF} {Length: 3798} {TRANSSPLICED} {Pfam: ATP dependent DNA ligase domain [PF01068.23, score=124.6]; DNA ligase N terminus [PF04675.16, score=120.6]; ATP dependent DNA ligase C terminal region [PF04679.17, score=58.3]; BRCT domain, a BRCA1 C-terminus domain [PF16589.7, score=42.6]; RNA ligase [PF09414.12, score=29.1]; BRCA1 C Terminus (BRCT) domain [PF00533.28, score=28.1]} {Human: ENSG00000174405, LIG4, DNA ligase 4, [RH, Score=648, Expect=0.0]} {Mouse: ENSMUSG00000049717, Lig4, ligase IV, DNA, ATP-dependent, [RH, Score=643, Expect=0.0]} {Dmel: FBgn0030506, Lig4, Ligase4, [RH, Score=252, Expect=3e-70]} {Celegans: WBGene00002985, lig-1, DNA ligase 1, [Score=133, Expect=8e-32]} {Smed: dd_Smed_v6_11363_0_1, dd_Smed_v6_11363_0_1, [RH, Score=568, Expect=0.0]} {RNA1509_4940} {RNA1310_2815} {RNA815_3459}

Mlig455_014442 {REF} {Length: 3787} {TRANSSPLICED} {Pfam: ATP dependent DNA ligase domain [PF01068.23, score=124.7]; DNA ligase N terminus [PF04675.16, score=120.6]; ATP dependent DNA ligase C terminal region [PF04679.17, score=58.3]; BRCT domain, a BRCA1 C-terminus domain [PF16589.7, score=42.5]; BRCA1 C Terminus (BRCT) domain [PF00533.28, score=28.1]; RNA ligase [PF09414.12, score=27.4]} {Human: ENSG00000174405, LIG4, DNA ligase 4, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000049717, Lig4, ligase IV, DNA, ATP-dependent, [RH, Score=641, Expect=0.0]} {Dmel: FBgn0030506, Lig4, Ligase4, [RH, Score=253, Expect=2e-70]} {Celegans: WBGene00002985, lig-1, DNA ligase 1, [Score=134, Expect=5e-32]} {Smed: dd_Smed_v6_11363_0_1, dd_Smed_v6_11363_0_1, [RH, Score=570, Expect=0.0]} {RNA1509_4940} {RNA1310_2815} {RNA815_3459}

Cumulative graph for MligTC455_31128

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 0.672 4.274 0.58387 1.00000
RegionR2 0.179 4.274 0.70741 1.00000
RegionR3 -0.795 4.274 0.04338 0.36391
RegionR4 0.413 4.274 0.37091 0.69415
RegionR5 0.891 4.274 0.00341 0.02593
RegionR6 -0.639 4.274 0.10630 0.59714
RegionR7 -0.278 4.274 0.61335 1.00000
RegionR8 -0.444 4.274 0.54429 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -7.655 4.274 0.05882 0.72421
RegenerationR2 -0.05 4.274 0.88655 1.00000
RegenerationR3 0.617 4.274 0.15152 0.58097
RegenerationR4 -0.155 4.274 0.70679 0.95572
RegenerationR5 -0.022 4.274 0.94646 1.00000
RegenerationR6 0.474 4.274 0.26455 0.61457
RegenerationBL -1.084 4.274 0.11331 0.39756
RegenerationTP 0.031 4.274 0.96081 1.00000


Genes with expression patterns similar to MligTC455_31128

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_31128 677 14.09 Mlig455_014434, Mlig455_014442

Neo: -

Age: Down-Down-Up

LIG4 6 1.000 1.000 1.000 1.000 1.000 1.000

Mlig455_014434 {REF} {Length: 3798} {TRANSSPLICED} {Pfam: ATP dependent DNA ligase domain [PF01068.23, score=124.6]; DNA ligase N terminus [PF04675.16, score=120.6]; ATP dependent DNA ligase C terminal region [PF04679.17, score=58.3]; BRCT domain, a BRCA1 C-terminus domain [PF16589.7, score=42.6]; RNA ligase [PF09414.12, score=29.1]; BRCA1 C Terminus (BRCT) domain [PF00533.28, score=28.1]} {Human: ENSG00000174405, LIG4, DNA ligase 4, [RH, Score=648, Expect=0.0]} {Mouse: ENSMUSG00000049717, Lig4, ligase IV, DNA, ATP-dependent, [RH, Score=643, Expect=0.0]} {Dmel: FBgn0030506, Lig4, Ligase4, [RH, Score=252, Expect=3e-70]} {Celegans: WBGene00002985, lig-1, DNA ligase 1, [Score=133, Expect=8e-32]} {Smed: dd_Smed_v6_11363_0_1, dd_Smed_v6_11363_0_1, [RH, Score=568, Expect=0.0]} {RNA1509_4940} {RNA1310_2815} {RNA815_3459}

Mlig455_014442 {REF} {Length: 3787} {TRANSSPLICED} {Pfam: ATP dependent DNA ligase domain [PF01068.23, score=124.7]; DNA ligase N terminus [PF04675.16, score=120.6]; ATP dependent DNA ligase C terminal region [PF04679.17, score=58.3]; BRCT domain, a BRCA1 C-terminus domain [PF16589.7, score=42.5]; BRCA1 C Terminus (BRCT) domain [PF00533.28, score=28.1]; RNA ligase [PF09414.12, score=27.4]} {Human: ENSG00000174405, LIG4, DNA ligase 4, [RH, Score=649, Expect=0.0]} {Mouse: ENSMUSG00000049717, Lig4, ligase IV, DNA, ATP-dependent, [RH, Score=641, Expect=0.0]} {Dmel: FBgn0030506, Lig4, Ligase4, [RH, Score=253, Expect=2e-70]} {Celegans: WBGene00002985, lig-1, DNA ligase 1, [Score=134, Expect=5e-32]} {Smed: dd_Smed_v6_11363_0_1, dd_Smed_v6_11363_0_1, [RH, Score=570, Expect=0.0]} {RNA1509_4940} {RNA1310_2815} {RNA815_3459}
2. MligTC455_31129 1008 21 Mlig455_005615, Mlig455_070184

Neo: Irradiation

Age: logFC(26M/2M)=0.545

Region-specific R5: 1.527

Region-enriched R5: 1.021/0.00725

LIG4 5.561 0.953 0.921 0.903 0.823 0.970 0.991

Mlig455_005615 {REF} {Length: 3975} {Pfam: ATP dependent DNA ligase domain [PF01068.23, score=124.6]; DNA ligase N terminus [PF04675.16, score=70.9]; ATP dependent DNA ligase C terminal region [PF04679.17, score=58.5]; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family [PF01248.28, score=57.1]; BRCT domain, a BRCA1 C-terminus domain [PF16589.7, score=42.4]; RNA ligase [PF09414.12, score=29.0]; BRCA1 C Terminus (BRCT) domain [PF00533.28, score=28.6]} {Human: ENSG00000174405, LIG4, DNA ligase 4, [Score=546, Expect=2e-178]} {Mouse: ENSMUSG00000049717, Lig4, ligase IV, DNA, ATP-dependent, [Score=541, Expect=7e-177]} {Dmel: FBgn0030506, Lig4, Ligase4, [Score=214, Expect=4e-57]} {Celegans: WBGene00002986, lig-4, LIGase, [RH, Score=127, Expect=1e-29]} {Smed: dd_Smed_v6_11363_0_1, dd_Smed_v6_11363_0_1, [Score=504, Expect=6e-163]} {RNA1509_4940} {RNA1310_2815} {RNA815_3459}

Mlig455_070184 {REF} {Length: 3787} {TRANSSPLICED} {Pfam: ATP dependent DNA ligase domain [PF01068.23, score=124.6]; DNA ligase N terminus [PF04675.16, score=120.6]; ATP dependent DNA ligase C terminal region [PF04679.17, score=58.3]; BRCT domain, a BRCA1 C-terminus domain [PF16589.7, score=42.6]; RNA ligase [PF09414.12, score=29.1]; BRCA1 C Terminus (BRCT) domain [PF00533.28, score=28.1]} {Human: ENSG00000174405, LIG4, DNA ligase 4, [RH, Score=648, Expect=0.0]} {Mouse: ENSMUSG00000049717, Lig4, ligase IV, DNA, ATP-dependent, [RH, Score=643, Expect=0.0]} {Dmel: FBgn0030506, Lig4, Ligase4, [RH, Score=253, Expect=3e-70]} {Celegans: WBGene00002985, lig-1, DNA ligase 1, [Score=134, Expect=7e-32]} {Smed: dd_Smed_v6_11363_0_1, dd_Smed_v6_11363_0_1, [RH, Score=566, Expect=0.0]} {RNA1509_4940} {RNA1310_2815, RNA1509_4940} {RNA1509_4940, RNA815_3459}
3. MligTC455_41596 581 12.09 Mlig455_029718

Neo: Irradiation

Age: -

Region-enriched R5: 1.903/0.00018

DBR1 3.369 0.840 0.827 - 0.744 - 0.958 Mlig455_029718 {REF} {Length: 3009} {TRANSSPLICED} {Pfam: Lariat debranching enzyme, C-terminal domain [PF05011.15, score=105.8]; Calcineurin-like phosphoesterase [PF00149.30, score=42.8]; Calcineurin-like phosphoesterase superfamily domain [PF12850.9, score=19.2]} {Human: ENSG00000138231, DBR1, debranching RNA lariats 1, [RH, Score=454, Expect=9e-154]} {Mouse: ENSMUSG00000032469, Dbr1, debranching RNA lariats 1, [RH, Score=445, Expect=2e-150]} {Dmel: FBgn0035838, ldbr, lariat debranching enzyme, [RH, Score=404, Expect=6e-135]} {Celegans: WBGene00000937, dbr-1, Lariat debranching enzyme, [RH, Score=338, Expect=1e-109]} {Smed: dd_Smed_v6_3274_0_1, dd_Smed_v6_3274_0_1, [RH, Score=434, Expect=4e-147]} {RNA1509_29892, RNA1509_45999, RNA1509_7249} {RNA1310_9562, RNA1509_29892, RNA1509_45999, RNA1509_7249} {RNA1509_29892, RNA1509_45999, RNA1509_7249, RNA815_3214.1}
4. MligTC455_49263 512 10.68 Mlig455_025933

Neo: Int S/G2/M

Age: logFC(26M/2M)=0.311

Region-enriched R5: 1.439/0.00123

2.477 0.791 0.735 - - - 0.951 Mlig455_025933 {REF} {Length: 2336} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=21.8]} {RNA1509_14753, RNA1509_37242, RNA1509_59972} {RNA1310_7813, RNA1509_14753, RNA1509_37242, RNA1509_59972} {RNA1509_14753, RNA1509_37242, RNA1509_59972, RNA815_11829.1}
5. MligTC455_26003 311 6.48 Mlig455_015543

Neo: -

Age: -

Region-enriched R5: 1.299/0.02445

RAB8B 2.471 0.760 0.754 - - - 0.957 Mlig455_015543 {REF} {Length: 2323} {Pfam: Ras family [PF00071.24, score=213.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=118.6]; ADP-ribosylation factor family [PF00025.23, score=63.1]; Elongation factor Tu GTP binding domain [PF00009.29, score=27.7]; Gtr1/RagA G protein conserved region [PF04670.14, score=27.7]; Signal recognition particle receptor beta subunit [PF09439.12, score=25.4]; 50S ribosome-binding GTPase [PF01926.25, score=20.5]; RsgA GTPase [PF03193.18, score=19.9]} {Human: ENSG00000166128, RAB8B, RAB8B, member RAS oncogene family, [RH, Score=290, Expect=2e-100]; ENSG00000167461, RAB8A, RAB8A, member RAS oncogene family, [RH, Score=286, Expect=7e-99]} {Mouse: ENSMUSG00000036943, Rab8b, RAB8B, member RAS oncogene family, [RH, Score=292, Expect=2e-101]; ENSMUSG00000003037, Rab8a, RAB8A, member RAS oncogene family, [RH, Score=289, Expect=5e-100]} {Dmel: FBgn0262518, Rab8, [RH, Score=273, Expect=8e-94]} {Celegans: WBGene00004272, rab-8, RAB family; Rab8, [RH, Score=278, Expect=8e-96]} {Smed: dd_Smed_v6_3485_0_1, dd_Smed_v6_3485_0_1, [RH, Score=272, Expect=8e-94]} {RNA1509_12702} {RNA1310_26159.1, RNA1509_12702} {RNA1509_12702, RNA815_11534.1}
6. MligTC455_30306 147 3.06 Mlig455_029651

Neo: -

Age: logFC(26M/2M)=-0.342

Region-enriched R5: 1.839/0.00256

CASP7 1.893 - - - - 0.963 0.930 Mlig455_029651 {REF} {Length: 4026} {Pfam: Caspase domain [PF00656.24, score=60.8]} {Human: ENSG00000165806, CASP7, caspase 7, [Score=83.6, Expect=1e-18]} {Mouse: ENSMUSG00000025076, Casp7, caspase 7, [Score=84.0, Expect=3e-19]; ENSMUSG00000027997, Casp6, caspase 6, [Score=80.1, Expect=6e-18]} {Dmel: FBgn0010501, Dcp-1, Death caspase-1, [Score=64.3, Expect=2e-12]} {Celegans: WBGene00000417, ced-3, Cell death protein 3 Cell death protein 3 subunit 1 Cell death protein 3 subunit 2, [Score=55.8, Expect=2e-09]} {Smed: dd_Smed_v6_3121_1_1, dd_Smed_v6_3121_1_1, [Score=80.9, Expect=1e-18]} {RNA1509_33490, RNA1509_44077} {RNA1310_23085, RNA1509_33490, RNA1509_44077} {RNA1509_33490, RNA1509_44077, RNA815_9619}
7. MligTC455_17120 139 2.9 Mlig455_027978

Neo: -

Age: Down-Up-Up

PCMT1 1.814 - - - 0.856 0.958 - Mlig455_027978 {REF} {Length: 870} {TRANSSPLICED} {Pfam: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) [PF01135.21, score=216.0]; Methyltransferase domain [PF13847.8, score=31.6]; Methyltransferase domain [PF13649.8, score=26.6]; tRNA methyltransferase complex GCD14 subunit [PF08704.12, score=23.1]; Methyltransferase domain [PF08241.14, score=21.4]; Methyltransferase domain [PF13679.8, score=19.7]} {Human: ENSG00000120265, PCMT1, protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=205, Expect=3e-66]} {Mouse: ENSMUSG00000116405, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=202, Expect=9e-65]; ENSMUSG00000019795, Pcmt1, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, [Score=202, Expect=9e-65]} {Dmel: FBgn0086768, Pcmt, Protein-L-isoaspartate (D-aspartate) O-methyltransferase, [Score=184, Expect=3e-58]} {Celegans: WBGene00003954, pcm-1, Protein-L-isoaspartate O-methyltransferase, [Score=189, Expect=3e-60]} {Smed: dd_Smed_v6_6199_0_1, dd_Smed_v6_6199_0_1, [Score=186, Expect=6e-59]} {RNA1310_30151} {RNA815_54398}
8. MligTC455_22775 94 1.96 Mlig455_045489

Neo: -

Age: -

Region-enriched R5: 3.609/0.00000

1.797 0.842 - - - - 0.955 Mlig455_045489 {REF} {Length: 2298} {Dmel: FBgn0032876, Cen, Centrocortin, [Score=64.3, Expect=3e-11]} {Smed: dd_Smed_v6_3478_0_1, dd_Smed_v6_3478_0_1, [Score=57.8, Expect=2e-09]} {RNA1310_54739} {RNA815_42744}
9. MligTC455_17311 130 2.71 Mlig455_018523

Neo: Irradiation

Age: Down-Up-Up

Region-enriched R5: 2.334/0.00107

1.781 - - - - 0.828 0.953 Mlig455_018523 {REF} {Length: 1992} {RNA1509_59995} {RNA1310_14658} {RNA815_25339}
10. MligTC455_13022 748 15.59 Mlig455_049274, Mlig455_050620

Neo: Int S/G2/M

Age: Up-Down-Down

Region-enriched R4: 2.175/0.00009
Region-enriched R5: 2.026/0.00001

1.772 - - - - 0.959 0.813

Mlig455_049274 {REF} {Length: 1993} {TRANSSPLICED} {RNA1509_11804} {RNA1310_14843} {RNA815_6608}

Mlig455_050620 {REF} {Length: 1986} {TRANSSPLICED} {RNA1509_11804} {RNA1310_14843} {RNA815_6608}
11. MligTC455_23989 1060 22.09 Mlig455_040688, Mlig455_064558

Neo: Int S/G2/M

Age: -

WEE2 1.76 - - - - 0.967 0.793

Mlig455_040688 {REF} {Length: 2318} {Pfam: Protein kinase domain [PF00069.27, score=106.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=79.2]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=22.9]} {Human: ENSG00000214102, WEE2, WEE1 homolog 2, [Score=106, Expect=1e-23]; ENSG00000263042, WEE2, WEE1 homolog 2, [Score=106, Expect=1e-23]} {Mouse: ENSMUSG00000037159, Wee2, WEE1 homolog 2 (S. pombe), [Score=111, Expect=2e-25]} {Dmel: FBgn0011737, Wee1, Wee1 kinase, [RH, Score=114, Expect=1e-26]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=72.0, Expect=6e-13]} {Smed: dd_Smed_v6_17244_0_1, dd_Smed_v6_17244_0_1, [RH, Score=95.9, Expect=6e-21]} {RNA1509_34481} {RNA1310_10526} {RNA815_4229.1}

Mlig455_064558 {REF} {Length: 2345} {Pfam: Protein kinase domain [PF00069.27, score=105.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=79.2]; Lipopolysaccharide kinase (Kdo/WaaP) family [PF06293.16, score=22.8]} {Human: ENSG00000263042, WEE2, WEE1 homolog 2, [Score=106, Expect=1e-23]; ENSG00000214102, WEE2, WEE1 homolog 2, [Score=106, Expect=1e-23]} {Mouse: ENSMUSG00000037159, Wee2, WEE1 homolog 2 (S. pombe), [Score=111, Expect=2e-25]} {Dmel: FBgn0011737, Wee1, Wee1 kinase, [RH, Score=114, Expect=1e-26]} {Celegans: WBGene00003916, par-1, Serine/threonine-protein kinase par-1, [Score=72.8, Expect=4e-13]} {Smed: dd_Smed_v6_17244_0_1, dd_Smed_v6_17244_0_1, [RH, Score=95.9, Expect=6e-21]} {RNA1509_34481} {RNA1310_10526, RNA1509_34481} {RNA1509_34481, RNA815_4229.1}
12. MligTC455_11366 258 5.38 Mlig455_016557

Neo: -

Age: -

Region-enriched R5: 1.351/0.01677

1.759 0.800 - - - - 0.959 Mlig455_016557 {REF} {Length: 3002} {TRANSSPLICED} {Pfam: Afadin- and alpha -actinin-Binding [PF11559.10, score=54.5]} {Mouse: ENSMUSG00000036825, Ssx2ip, synovial sarcoma, X 2 interacting protein, [RH, Score=92.0, Expect=1e-19]} {RNA1509_10737, RNA1509_37638, RNA1509_45686} {RNA1310_9399, RNA1509_10737, RNA1509_37638, RNA1509_45686} {RNA1509_10737, RNA1509_37638, RNA1509_45686, RNA815_26177}
13. MligTC455_32181 167 3.47 Mlig455_024277

Neo: Irradiation

Age: logFC(26M/2M)=0.310

GTF2H2C_2 1.746 - 0.783 - - - 0.963 Mlig455_024277 {REF} {Length: 1797} {TRANSSPLICED} {Pfam: Ssl1-like [PF04056.16, score=211.4]; von Willebrand factor type A domain [PF13519.8, score=35.9]; TFIIH C1-like domain [PF07975.14, score=33.0]} {Human: ENSG00000274675, GTF2H2C_2, GTF2H2 family member C, copy 2, [RH, Score=305, Expect=5e-100]; ENSG00000183474, GTF2H2C, GTF2H2 family member C, [RH, Score=305, Expect=5e-100]; ENSG00000276910, GTF2H2, general transcription factor IIH subunit 2, [RH, Score=301, Expect=1e-98]; ENSG00000275045, GTF2H2, general transcription factor IIH subunit 2, [RH, Score=301, Expect=1e-98]; ENSG00000145736, GTF2H2, general transcription factor IIH subunit 2, [RH, Score=301, Expect=1e-98]} {Mouse: ENSMUSG00000021639, Gtf2h2, general transcription factor II H, polypeptide 2, [RH, Score=306, Expect=9e-101]} {Dmel: FBgn0037202, Ssl1, Suppressor of stem-loop mutation, [RH, Score=328, Expect=8e-109]} {Celegans: WBGene00011814, T16H12.4, General transcription factor IIH subunit 2, [RH, Score=251, Expect=1e-79]} {Smed: dd_Smed_v6_7018_0_1, dd_Smed_v6_7018_0_1, [RH, Score=278, Expect=5e-90]} {RNA1509_19373} {RNA1310_19775, RNA1509_19373} {RNA1509_19373, RNA815_8031}
14. MligTC455_36836 71 1.47 Mlig455_048099

Neo: -

Age: -

1.742 - - - - 0.950 0.792 Mlig455_048099 {REF} {Length: 1394} {TRANSSPLICED} {RNA1509_58153} {RNA1310_20702.1, RNA1509_58153} {RNA1509_58153, RNA815_50889}
15. MligTC455_50867 114 2.37 Mlig455_022658

Neo: Germline

Age: -

Region-enriched R5: 2.337/0.01958

1.676 - - - 0.716 - 0.960 Mlig455_022658 {REF} {Length: 740} {NoTransDecoderORF} {RNA1310_72759} {RNA815_30637.1}
16. MligTC455_02593 58 1.21 Mlig455_067504

Neo: -

Age: logFC(26M/2M)=-0.359

MX2 0.972 - - - - 0.972 - Mlig455_067504 {REF} {Length: 3763} {Pfam: Dynamin central region [PF01031.22, score=149.9]; Dynamin family [PF00350.25, score=124.7]; Dynamin GTPase effector domain [PF02212.20, score=53.5]; 50S ribosome-binding GTPase [PF01926.25, score=23.7]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=22.7]; AAA ATPase domain [PF13175.8, score=22.5]} {Human: ENSG00000183486, MX2, MX dynamin like GTPase 2, [RH, Score=347, Expect=1e-107]; ENSG00000157601, MX1, MX dynamin like GTPase 1, [RH, Score=333, Expect=1e-102]} {Mouse: ENSMUSG00000023341, Mx2, MX dynamin-like GTPase 2, [RH, Score=339, Expect=2e-105]} {Dmel: FBgn0003392, shi, shibire, [Score=154, Expect=3e-38]} {Celegans: WBGene00001130, dyn-1, Dynamin, [Score=166, Expect=3e-42]} {Smed: dd_Smed_v6_6863_0_4, dd_Smed_v6_6863_0_4, [Score=164, Expect=7e-42]} {RNA1509_52436} {RNA1310_1482.1} {RNA815_3194}
17. MligTC455_24435 863 17.98 Mlig455_027142

Neo: Irradiation

Age: logFC(26M/2M)=0.217

Region-enriched R5: 1.478/0.00000

ATIC 0.968 - - - - - 0.968 Mlig455_027142 {REF} {Length: 2892} {TRANSSPLICED} {Pfam: AICARFT/IMPCHase bienzyme [PF01808.20, score=290.3]; MGS-like domain [PF02142.24, score=74.9]} {Human: ENSG00000138363, ATIC, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, [RH, Score=675, Expect=0.0]} {Mouse: ENSMUSG00000026192, Atic, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, [RH, Score=670, Expect=0.0]} {Dmel: FBgn0039241, CG11089, [RH, Score=690, Expect=0.0]} {Celegans: WBGene00016957, atic-1, 5-Aminoimidazole-4-carboxamide ribonucleotide formylTransferase/IMP Cyclohydrolase homolog, [RH, Score=580, Expect=0.0]} {Smed: dd_Smed_v6_3445_0_1, dd_Smed_v6_3445_0_1, [RH, Score=635, Expect=0.0]} {RNA1509_6261} {RNA1310_7712.1, RNA1509_6261} {RNA1509_6261, RNA815_2690.1}
18. MligTC455_50864 44 0.91 Mlig455_049401

Neo: -

Age: logFC(26M/2M)=0.638

BAG3 0.962 - - - - - 0.962 Mlig455_049401 {REF} {Length: 2299} {TRANSSPLICED} {Pfam: WW domain [PF00397.28, score=45.1]} {Human: ENSG00000151929, BAG3, BCL2 associated athanogene 3, [RH, Score=69.7, Expect=2e-14]} {Mouse: ENSMUSG00000030847, Bag3, BCL2-associated athanogene 3, [RH, Score=72.4, Expect=2e-15]} {Dmel: FBgn0003557, Su(dx), Suppressor of deltex, [Score=47.8, Expect=5e-07]} {Celegans: WBGene00007009, wwp-1, E3 ubiquitin-protein ligase, [Score=52.0, Expect=1e-08]} {Smed: dd_Smed_v6_3939_0_1, dd_Smed_v6_3939_0_1, [Score=53.9, Expect=1e-09]} {RNA1509_20613} {RNA1310_28133} {RNA815_20034}
19. MligTC455_32117 121 2.52 Mlig455_061050

Neo: -

Age: -

CEBPD 0.96 - - - - - 0.960 Mlig455_061050 {REF} {Length: 2187} {TRANSSPLICED} {Pfam: Basic region leucine zipper [PF07716.17, score=30.6]; bZIP transcription factor [PF00170.23, score=24.3]} {Human: ENSG00000221869, CEBPD, CCAAT enhancer binding protein delta, [Score=52.4, Expect=2e-07]} {Mouse: ENSMUSG00000071637, Cebpd, CCAAT/enhancer binding protein (C/EBP), delta, [Score=52.4, Expect=1e-07]} {RNA1509_46169} {RNA1310_36388} {RNA815_32515}
20. MligTC455_41610 149 3.1 Mlig455_005689

Neo: -

Age: Down-Down-Down

0.957 - - - - - 0.957 Mlig455_005689 {REF} {Length: 1271} {Smed: dd_Smed_v6_12396_0_1, dd_Smed_v6_12396_0_1, [Score=46.2, Expect=5e-06]} {RNA1509_26983, RNA1509_29260} {RNA1310_55944, RNA1509_26983} {RNA1509_26983, RNA815_3780.1}
21. MligTC455_41113 631 13.14 Mlig455_053556

Neo: -

Age: -

Region-enriched R5: 1.520/0.04923

OPA1 0.955 - - - - 0.955 - Mlig455_053556 {REF} {Length: 3245} {TRANSSPLICED} {Pfam: Dynamin-like GTPase OPA1 C-terminal [PF19434.1, score=602.1]; Dynamin family [PF00350.25, score=122.8]; 50S ribosome-binding GTPase [PF01926.25, score=23.5]} {Human: ENSG00000198836, OPA1, OPA1, mitochondrial dynamin like GTPase, [RH, Score=730, Expect=0.0]} {Mouse: ENSMUSG00000038084, Opa1, OPA1, mitochondrial dynamin like GTPase, [RH, Score=726, Expect=0.0]} {Dmel: FBgn0261276, Opa1, Optic atrophy 1, [RH, Score=699, Expect=0.0]} {Celegans: WBGene00001134, eat-3, [RH, Score=701, Expect=0.0]} {Smed: dd_Smed_v6_7981_0_2, dd_Smed_v6_7981_0_2, [RH, Score=644, Expect=0.0]} {RNA1509_34607, RNA1509_45369} {RNA1310_4411, RNA1509_45369} {RNA1509_45369, RNA815_1436}
22. MligTC455_21505 219 4.57 Mlig455_004243, Mlig455_063139

Neo: Int S/G2/M

Age: -

Region-enriched R5: 2.566/0.02847

0.953 - - - - - 0.953

Mlig455_004243 {REF} {Length: 3420} {Pfam: Replication protein A OB domain [PF16900.7, score=34.4]; OB-fold nucleic acid binding domain [PF01336.27, score=20.7]} {RNA1509_42291} {RNA1310_16322} {RNA815_63367}

Mlig455_063139 {REF} {Length: 2398} {TRANSSPLICED} {Pfam: Replication protein A OB domain [PF16900.7, score=26.7]} {RNA1509_42291} {RNA1310_16322, RNA1509_42291} {RNA1509_42291, RNA815_63367}
23. MligTC455_25047 135 2.82 Mlig455_041213

Neo: -

Age: -

RNF31 0.95 - - - - - 0.950 Mlig455_041213 {REF} {Length: 3533} {TRANSSPLICED} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=39.2]; E3 Ubiquitin Ligase RBR C-terminal domain [PF18091.3, score=27.3]; Domain of unknown function (DUF4573) [PF15140.8, score=21.0]} {Human: ENSG00000285152, RNF31, ring finger protein 31, [Score=188, Expect=2e-49]; ENSG00000092098, RNF31, ring finger protein 31, [Score=188, Expect=2e-49]; ENSG00000284845, AL136295.10, novel transcript, [Score=185, Expect=3e-50]; ENSG00000259529, AL136295.5, novel transcript, [Score=185, Expect=3e-50]} {Mouse: ENSMUSG00000047098, Rnf31, ring finger protein 31, [Score=184, Expect=3e-48]} {Dmel: FBgn0031857, LUBEL, Linear Ubiquitin E3 ligase, [Score=171, Expect=7e-44]} {Smed: dd_Smed_v6_4074_0_1, dd_Smed_v6_4074_0_1, [RH, Score=134, Expect=1e-32]} {RNA1509_18940} {RNA1310_17723.1} {RNA815_23151}
24. MligTC455_28451 318 6.62 Mlig455_043942

Neo: Neoblast, stringent

Age: -

CTPS1 0.95 - - - - - 0.950 Mlig455_043942 {REF} {Length: 3489} {TRANSSPLICED} {Pfam: CTP synthase N-terminus [PF06418.16, score=410.7]; Glutamine amidotransferase class-I [PF00117.30, score=183.5]; Peptidase C26 [PF07722.15, score=19.2]; CobQ/CobB/MinD/ParA nucleotide binding domain [PF01656.25, score=18.9]} {Human: ENSG00000171793, CTPS1, CTP synthase 1, [RH, Score=761, Expect=0.0]} {Mouse: ENSMUSG00000028633, Ctps, cytidine 5'-triphosphate synthase, [RH, Score=760, Expect=0.0]} {Dmel: FBgn0266452, CTPsyn, CTP synthase, [RH, Score=700, Expect=0.0]} {Celegans: WBGene00012316, ctps-1, CTP synthase, [RH, Score=572, Expect=0.0]} {Smed: dd_Smed_v6_5375_0_1, dd_Smed_v6_5375_0_1, [RH, Score=711, Expect=0.0]} {RNA1509_22075, RNA1509_38234} {RNA1310_3772, RNA1509_22075, RNA1509_38234} {RNA1509_22075, RNA1509_38234, RNA815_4144}
25. MligTC455_47028 572 11.91 Mlig455_061142

Neo: -

Age: -

DHDDS 0.95 - - - - 0.950 - Mlig455_061142 {REF} {Length: 1426} {TRANSSPLICED} {Pfam: Putative undecaprenyl diphosphate synthase [PF01255.21, score=239.9]} {Human: ENSG00000117682, DHDDS, dehydrodolichyl diphosphate synthase subunit, [RH, Score=282, Expect=2e-93]} {Mouse: ENSMUSG00000012117, Dhdds, dehydrodolichyl diphosphate synthase, [RH, Score=281, Expect=5e-93]} {Dmel: FBgn0029980, CG10778, [RH, Score=250, Expect=2e-81]} {Celegans: WBGene00044025, T01G1.4, Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific), [RH, Score=221, Expect=2e-70]} {Smed: dd_Smed_v6_6603_0_1, dd_Smed_v6_6603_0_1, [RH, Score=273, Expect=1e-90]} {RNA1509_4999} {RNA1310_27885} {RNA815_2608.1}

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