Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_44892 | 642 | 13.37 | Mlig455_048764 | Neo: - Age: logFC(26M/2M)=0.308 |
SMARCC2 | Mlig455_048764 {REF} {Length: 4246} {Pfam: SWIRM-associated domain at the C-terminal [PF16498.7, score=52.9]; SWIRM-associated region 1 [PF16495.7, score=25.2]} {Human: ENSG00000139613, SMARCC2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000025369, Smarcc2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, [Score=110, Expect=2e-24]} {Dmel: FBgn0002783, mor, moira, [Score=89.0, Expect=6e-18]} {Celegans: WBGene00004203, swsn-1, SWI/SNF nucleosome remodeling complex component; SWI3-like protein, [Score=94.4, Expect=7e-20]} {Smed: dd_Smed_v6_1804_0_1, dd_Smed_v6_1804_0_1, [Score=90.1, Expect=2e-18]} {RNA1509_49479} {RNA1310_2189} {RNA815_8217} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -2.184 | 4.008 | 0.12390 | 0.71803 | |
RegionR2 | 0.809 | 4.008 | 0.18642 | 0.53946 | |
RegionR3 | -0.049 | 4.008 | 0.93061 | 1.00000 | |
RegionR4 | -0.036 | 4.008 | 0.94980 | 1.00000 | |
RegionR5 | 0.991 | 4.008 | 0.02114 | 0.10092 | |
RegionR6 | 0.975 | 4.008 | 0.04486 | 0.39583 | |
RegionR7 | 0.716 | 4.008 | 0.23107 | 0.85453 | |
RegionR8 | -1.222 | 4.008 | 0.21444 | 0.81890 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | 1.789 | 4.008 | 0.34436 | 1.00000 | |
RegenerationR2 | 0.195 | 4.008 | 0.69958 | 0.95626 | |
RegenerationR3 | 0.71 | 4.008 | 0.20879 | 0.64432 | |
RegenerationR4 | 0.242 | 4.008 | 0.65981 | 0.93815 | |
RegenerationR5 | 0.147 | 4.008 | 0.76741 | 0.97818 | |
RegenerationR6 | 0.705 | 4.008 | 0.17490 | 0.50755 | |
RegenerationBL | 1.395 | 4.008 | 0.02067 | 0.15575 | |
RegenerationTP | 0.862 | 4.008 | 0.23918 | 0.68497 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_44892 | 642 | 13.37 | Mlig455_048764 | Neo: - Age: logFC(26M/2M)=0.308 |
SMARCC2 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_048764 {REF} {Length: 4246} {Pfam: SWIRM-associated domain at the C-terminal [PF16498.7, score=52.9]; SWIRM-associated region 1 [PF16495.7, score=25.2]} {Human: ENSG00000139613, SMARCC2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2, [Score=108, Expect=6e-24]} {Mouse: ENSMUSG00000025369, Smarcc2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, [Score=110, Expect=2e-24]} {Dmel: FBgn0002783, mor, moira, [Score=89.0, Expect=6e-18]} {Celegans: WBGene00004203, swsn-1, SWI/SNF nucleosome remodeling complex component; SWI3-like protein, [Score=94.4, Expect=7e-20]} {Smed: dd_Smed_v6_1804_0_1, dd_Smed_v6_1804_0_1, [Score=90.1, Expect=2e-18]} {RNA1509_49479} {RNA1310_2189} {RNA815_8217} |
2. | MligTC455_37126 | 1036 | 21.59 | Mlig455_059720 | Neo: - Age: - |
POLR1A | 2.607 | 0.831 | 0.806 | - | 0.970 | - | - | Mlig455_059720 {REF} {Length: 1092} {Pfam: RNA polymerase Rpb1, domain 5 [PF04998.19, score=52.0]} {Human: ENSG00000068654, POLR1A, RNA polymerase I subunit A, [Score=120, Expect=2e-30]} {Mouse: ENSMUSG00000049553, Polr1a, polymerase (RNA) I polypeptide A, [Score=120, Expect=1e-30]} {Dmel: FBgn0019938, RpI1, RNA polymerase I subunit, [Score=117, Expect=1e-29]} {Celegans: WBGene00012999, rpoa-1, RNA POlymerase I (A) subunit, [Score=107, Expect=3e-26]} {Smed: dd_Smed_v6_9059_1_1, dd_Smed_v6_9059_1_1, [RH, Score=101, Expect=1e-27]} {RNA1509_15567} {RNA1310_628.3} {RNA815_11233} |
3. | MligTC455_16422 | 643 | 13.39 | Mlig455_022617 | Neo: Irradiation Age: - Region-enriched R5: 1.388/0.00048 |
PFAS | 2.538 | 0.757 | - | - | 0.823 | - | 0.958 | Mlig455_022617 {REF} {Length: 4732} {TRANSSPLICED} {Pfam: CobB/CobQ-like glutamine amidotransferase domain [PF13507.8, score=279.2]; AIR synthase related protein, C-terminal domain [PF02769.24, score=102.4]; Formylglycinamide ribonucleotide amidotransferase linker domain [PF18072.3, score=41.3]} {Human: ENSG00000178921, PFAS, phosphoribosylformylglycinamidine synthase, [RH, Score=988, Expect=0.0]} {Mouse: ENSMUSG00000020899, Pfas, phosphoribosylformylglycinamidine synthase (FGAR amidotransferase), [RH, Score=1011, Expect=0.0]} {Dmel: FBgn0000052, ade2, adenosine 2, [RH, Score=898, Expect=0.0]} {Celegans: WBGene00008654, F10F2.2, Probable phosphoribosylformylglycinamidine synthase, [RH, Score=926, Expect=0.0]} {Smed: dd_Smed_v6_5130_0_1, dd_Smed_v6_5130_0_1, [RH, Score=950, Expect=0.0]} {RNA1509_55250, RNA1509_6392} {RNA1310_1527.1, RNA1509_55250} {RNA1509_55250, RNA815_842.1} |
4. | MligTC455_20391 | 3465 | 72.19 | Mlig455_000953 | Neo: Neoblast, stringent Age: - Region-enriched R5: 1.069/0.00002 Regeneration-upregulated BL: 1.238 Regeneration-enriched BL: 1.238 |
RBBP4 | 2.497 | - | 0.721 | - | 0.826 | - | 0.950 | Mlig455_000953 {REF} {Length: 2522} {TRANSSPLICED} {Pfam: Histone-binding protein RBBP4 or subunit C of CAF1 complex [PF12265.10, score=97.9]; WD domain, G-beta repeat [PF00400.34, score=93.9]; Eukaryotic translation initiation factor eIF2A [PF08662.13, score=24.1]; Anaphase-promoting complex subunit 4 WD40 domain [PF12894.9, score=19.6]} {Human: ENSG00000162521, RBBP4, RB binding protein 4, chromatin remodeling factor, [RH, Score=758, Expect=0.0]; ENSG00000102054, RBBP7, RB binding protein 7, chromatin remodeling factor, [RH, Score=724, Expect=0.0]} {Mouse: ENSMUSG00000057236, Rbbp4, retinoblastoma binding protein 4, chromatin remodeling factor, [RH, Score=758, Expect=0.0]; ENSMUSG00000031353, Rbbp7, retinoblastoma binding protein 7, chromatin remodeling factor, [RH, Score=726, Expect=0.0]} {Dmel: FBgn0263979, Caf1-55, Chromatin assembly factor 1, p55 subunit, [RH, Score=736, Expect=0.0]} {Celegans: WBGene00003036, lin-53, Probable histone-binding protein lin-53, [RH, Score=629, Expect=0.0]} {Smed: dd_Smed_v6_2065_0_1, dd_Smed_v6_2065_0_1, [RH, Score=711, Expect=0.0]} {RNA1509_2959, RNA1509_44857, RNA1509_56911, RNA1509_58447} {RNA1310_7929.2, RNA1509_2959, RNA1509_44857, RNA1509_56911, RNA1509_58447} {RNA1509_2959, RNA1509_44857, RNA1509_56911, RNA1509_58447, RNA815_2262.1} |
5. | MligTC455_18751 | 300 | 6.26 | Mlig455_011845 | Neo: Irradiation Age: logFC(26M/2M)=0.450 |
1.781 | - | - | - | 0.963 | - | 0.818 | Mlig455_011845 {REF} {Length: 1955} {RNA1509_21437} {RNA1310_70292.3} {RNA815_45917.2} | |
6. | MligTC455_40884 | 1166 | 24.29 | Mlig455_051978 | Neo: Neoblast, stringent Age: Up-Down-Down Regeneration-enriched R6: 1.871 |
ZNF512B | 1.75 | - | - | - | 0.795 | - | 0.955 | Mlig455_051978 {REF} {Length: 5501} {Human: ENSG00000196700, ZNF512B, zinc finger protein 512B, [Score=53.1, Expect=4e-06]} {Mouse: ENSMUSG00000020396, Nefh, neurofilament, heavy polypeptide, [Score=56.2, Expect=3e-07]} {Celegans: WBGene00010357, H03A11.2, [Score=50.4, Expect=1e-05]} {RNA1509_8438} {RNA1310_271} {RNA815_57.1} |
7. | MligTC455_31671 | 799 | 16.64 | Mlig455_007386 | Neo: Irradiation Age: - |
RAD21 | 0.968 | - | - | - | 0.968 | - | - | Mlig455_007386 {REF} {Length: 3384} {TRANSSPLICED} {Pfam: N terminus of Rad21 / Rec8 like protein [PF04825.15, score=137.7]} {Human: ENSG00000164754, RAD21, RAD21 cohesin complex component, [RH, Score=274, Expect=5e-85]} {Mouse: ENSMUSG00000022314, Rad21, RAD21 cohesin complex component, [RH, Score=275, Expect=4e-85]} {Dmel: FBgn0260987, vtd, verthandi, [RH, Score=276, Expect=4e-85]} {Celegans: WBGene00000591, coh-1, COHesin family, [RH, Score=201, Expect=6e-58]} {Smed: dd_Smed_v6_4032_0_1, dd_Smed_v6_4032_0_1, [RH, Score=288, Expect=3e-89]} {RNA1509_59154, RNA1509_59509} {RNA1310_10984.1, RNA1509_59154, RNA1509_59509} {RNA1509_59154, RNA1509_59509, RNA815_23741} |
8. | MligTC455_18659 | 114 | 2.39 | Mlig455_021331 | Neo: - Age: - |
0.966 | - | - | - | 0.966 | - | - | Mlig455_021331 {REF} {Length: 1597} {Pfam: Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 [PF03318.15, score=31.6]} {Celegans: WBGene00016289, lntl-1, LIN-24 (Twenty-four) Like, [RH, Score=147, Expect=4e-42]} {RNA1509_6800} {RNA1310_20535, RNA1509_6800} {RNA1509_6800, RNA815_6611.1} | |
9. | MligTC455_47328 | 471 | 9.82 | Mlig455_025846, Mlig455_025907 | Neo: - Age: logFC(26M/2M)=0.517 |
DSTYK | 0.966 | - | - | - | - | 0.966 | - | Mlig455_025846 {REF} {Length: 3841} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=89.9]; Protein kinase domain [PF00069.27, score=81.5]; Dynamin family [PF00350.25, score=72.6]; 50S ribosome-binding GTPase [PF01926.25, score=31.2]; Elongation factor Tu GTP binding domain [PF00009.29, score=22.9]} {Human: ENSG00000133059, DSTYK, dual serine/threonine and tyrosine protein kinase, [Score=164, Expect=9e-41]} {Mouse: ENSMUSG00000042046, Dstyk, dual serine/threonine and tyrosine protein kinase, [Score=180, Expect=3e-46]} {Dmel: FBgn0000826, png, pan gu, [Score=70.5, Expect=1e-12]} {Celegans: WBGene00000812, csk-1, Tyrosine-protein kinase csk-1, [Score=72.0, Expect=1e-12]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [Score=359, Expect=2e-109]} {RNA1509_5996} {RNA1310_2101.1} {RNA815_1774} Mlig455_025907 {REF} {Length: 3323} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=89.9]; Protein kinase domain [PF00069.27, score=81.5]; Dynamin family [PF00350.25, score=72.6]; 50S ribosome-binding GTPase [PF01926.25, score=31.3]; Elongation factor Tu GTP binding domain [PF00009.29, score=22.9]} {Human: ENSG00000133059, DSTYK, dual serine/threonine and tyrosine protein kinase, [Score=164, Expect=9e-41]} {Mouse: ENSMUSG00000042046, Dstyk, dual serine/threonine and tyrosine protein kinase, [Score=180, Expect=3e-46]} {Dmel: FBgn0000826, png, pan gu, [Score=70.1, Expect=1e-12]} {Celegans: WBGene00000812, csk-1, Tyrosine-protein kinase csk-1, [Score=72.0, Expect=1e-12]} {Smed: dd_Smed_v6_1371_0_1, dd_Smed_v6_1371_0_1, [Score=361, Expect=7e-110]} {RNA1509_5996} {RNA1310_2101.1} {RNA815_1774} |
10. | MligTC455_37797 | 1708 | 35.59 | Mlig455_052264, Mlig455_052350 | Neo: Neoblast, stringent Age: logFC(26M/2M)=-0.294 Regeneration-enriched BL: 1.878 |
LRWD1 | 0.963 | - | - | - | 0.963 | - | - | Mlig455_052264 {REF} {Length: 5281} {TRANSSPLICED} {Pfam: NAB conserved region 2 (NCD2) [PF04905.15, score=67.7]; Leucine rich repeat [PF13855.8, score=30.0]; WD domain, G-beta repeat [PF00400.34, score=24.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=22.5]} {Human: ENSG00000161036, LRWD1, leucine rich repeats and WD repeat domain containing 1, [RH, Score=206, Expect=3e-55]} {Mouse: ENSMUSG00000029703, Lrwd1, leucine-rich repeats and WD repeat domain containing 1, [RH, Score=211, Expect=6e-57]} {Dmel: FBgn0032391, escl, [Score=57.8, Expect=6e-08]} {Celegans: WBGene00003107, mab-10, [RH, Score=55.1, Expect=4e-07]} {Smed: dd_Smed_v6_2942_0_1, dd_Smed_v6_2942_0_1, [RH, Score=437, Expect=3e-127]} {RNA1509_1906} {RNA1310_947} {RNA815_870} Mlig455_052350 {REF} {Length: 5956} {TRANSSPLICED} {Pfam: NAB conserved region 2 (NCD2) [PF04905.15, score=67.8]; Leucine rich repeat [PF13855.8, score=30.0]; WD domain, G-beta repeat [PF00400.34, score=24.3]; Leucine Rich repeats (2 copies) [PF12799.9, score=22.5]} {Human: ENSG00000161036, LRWD1, leucine rich repeats and WD repeat domain containing 1, [RH, Score=206, Expect=3e-55]} {Mouse: ENSMUSG00000029703, Lrwd1, leucine-rich repeats and WD repeat domain containing 1, [RH, Score=211, Expect=6e-57]} {Dmel: FBgn0032391, escl, [Score=57.8, Expect=6e-08]} {Celegans: WBGene00003107, mab-10, [RH, Score=55.1, Expect=4e-07]} {Smed: dd_Smed_v6_2942_0_1, dd_Smed_v6_2942_0_1, [RH, Score=437, Expect=3e-127]} {RNA1509_1906} {RNA1310_947, RNA1509_1906} {RNA1509_1906, RNA815_870} |
11. | MligTC455_26503 | 114 | 2.37 | Mlig455_055217 | Neo: Int S/G2/M Age: - Region-enriched R4: 7.372/0.00058 |
CPSF6 | 0.96 | - | - | - | 0.960 | - | - | Mlig455_055217 {REF} {Length: 5089} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=26.5]} {Human: ENSG00000111605, CPSF6, cleavage and polyadenylation specific factor 6, [RH, Score=139, Expect=1e-34]} {Mouse: ENSMUSG00000055531, Cpsf6, cleavage and polyadenylation specific factor 6, [RH, Score=139, Expect=2e-34]} {Dmel: FBgn0035872, CG7185, [RH, Score=133, Expect=3e-32]} {Celegans: WBGene00008362, cfim-2, Cleavage Factor IM (CFIm) homolog, [RH, Score=96.7, Expect=7e-21]} {Smed: dd_Smed_v6_4839_0_1, dd_Smed_v6_4839_0_1, [RH, Score=152, Expect=2e-39]} {RNA1509_8357} {RNA1310_5998} {RNA815_15488} |
12. | MligTC455_36435 | 206 | 4.3 | Mlig455_063032 | Neo: - Age: - |
RTL1 | 0.96 | - | - | - | 0.960 | - | - | Mlig455_063032 {REF} {Length: 7806} {Pfam: RNase H-like domain found in reverse transcriptase [PF17919.3, score=45.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=24.6]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=65.9, Expect=1e-10]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=108, Expect=1e-24]} {RNA1509_11174} {RNA1310_21447} {RNA815_26029.1} |
13. | MligTC455_40792 | 548 | 11.41 | Mlig455_014009 | Neo: - Age: - Region-enriched R5: 1.451/0.00073 |
CCDC6 | 0.954 | - | - | - | - | - | 0.954 | Mlig455_014009 {REF} {Length: 2755} {TRANSSPLICED} {Pfam: Uncharacterized conserved protein H4 (DUF2046) [PF09755.11, score=334.1]; CENP-Q, a CENPA-CAD centromere complex subunit [PF13094.8, score=23.6]} {Human: ENSG00000108091, CCDC6, coiled-coil domain containing 6, [RH, Score=274, Expect=1e-87]} {Mouse: ENSMUSG00000048701, Ccdc6, coiled-coil domain containing 6, [RH, Score=276, Expect=8e-89]} {Dmel: FBgn0036685, CG6664, [RH, Score=240, Expect=4e-74]} {Celegans: WBGene00011645, T09B9.4, [RH, Score=92.8, Expect=2e-20]} {Smed: dd_Smed_v6_6765_0_1, dd_Smed_v6_6765_0_1, [RH, Score=250, Expect=6e-79]} {RNA1509_36276, RNA1509_44828, RNA1509_48420, RNA1509_53667, RNA1509_8527} {RNA1310_18598, RNA1509_36276, RNA1509_44828, RNA1509_48420, RNA1509_53667, RNA1509_8527} {RNA1509_36276, RNA1509_44828, RNA1509_48420, RNA1509_53667, RNA1509_8527, RNA815_15333} |
14. | MligTC455_44773 | 344 | 7.16 | Mlig455_056369 | Neo: Int S/G2/M Age: Down-Up-Down Region-enriched R5: 2.057/0.01861 |
0.952 | - | - | - | - | - | 0.952 | Mlig455_056369 {REF} {Length: 2569} {TRANSSPLICED} {RNA1509_31340, RNA1509_40584} {RNA1310_41204, RNA1509_31340, RNA1509_40584} {RNA1509_31340, RNA1509_40584, RNA815_47747} | |
15. | MligTC455_48267 | 778 | 16.21 | Mlig455_047346 | Neo: - Age: Up-Down-Up |
LENG8 | 0.95 | - | - | - | - | - | 0.950 | Mlig455_047346 {REF} {Length: 3202} {Pfam: SAC3/GANP family [PF03399.18, score=76.1]} {Human: ENSG00000276458, LENG8, leukocyte receptor cluster member 8, [RH, Score=286, Expect=6e-86]; ENSG00000167615, LENG8, leukocyte receptor cluster member 8, [RH, Score=286, Expect=6e-86]; ENSG00000276681, LENG8, leukocyte receptor cluster member 8, [RH, Score=286, Expect=6e-86]; ENSG00000274305, LENG8, leukocyte receptor cluster member 8, [RH, Score=286, Expect=6e-86]} {Mouse: ENSMUSG00000035545, Leng8, leukocyte receptor cluster (LRC) member 8, [RH, Score=260, Expect=9e-77]} {Dmel: FBgn0032305, CG6700, [RH, Score=253, Expect=1e-73]} {Celegans: WBGene00017158, hpo-10, [RH, Score=192, Expect=5e-53]} {Smed: dd_Smed_v6_2926_0_3, dd_Smed_v6_2926_0_3, [RH, Score=278, Expect=2e-83]} {RNA1509_6802} {RNA1310_1963.1} {RNA815_2189.1} |