Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_49480 | 3325 | 69.28 | Mlig455_061462 | Neo: - Age: - Regeneration-upregulated BL: 1.148 Regeneration-enriched BL: 1.148 |
RBM39 | Mlig455_061462 {REF} {Length: 2374} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=136.6]; linker between RRM2 and RRM3 domains in RBM39 protein [PF15519.8, score=60.2]} {Human: ENSG00000131051, RBM39, RNA binding motif protein 39, [RH, Score=363, Expect=1e-118]} {Mouse: ENSMUSG00000027620, Rbm39, RNA binding motif protein 39, [RH, Score=363, Expect=9e-119]} {Dmel: FBgn0031883, Caper, [RH, Score=342, Expect=1e-109]} {Celegans: WBGene00021921, Y55F3AM.3, [RH, Score=258, Expect=6e-78]} {Smed: dd_Smed_v6_1932_0_1, dd_Smed_v6_1932_0_1, [RH, Score=276, Expect=2e-86]} {RNA1509_4239, RNA1509_43417, RNA1509_9704} {RNA1310_3908, RNA1509_4239, RNA1509_43417} {RNA1509_4239, RNA1509_43417, RNA815_1081.1} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -0.665 | 6.277 | 0.30708 | 0.95600 | |
RegionR2 | 0.216 | 6.277 | 0.47589 | 0.86107 | |
RegionR3 | -0.073 | 6.277 | 0.77473 | 1.00000 | |
RegionR4 | 0.426 | 6.277 | 0.14142 | 0.38479 | |
RegionR5 | 0.257 | 6.277 | 0.26607 | 0.58933 | |
RegionR6 | 0.037 | 6.277 | 0.88488 | 1.00000 | |
RegionR7 | 0.304 | 6.277 | 0.30023 | 0.93506 | |
RegionR8 | -0.502 | 6.277 | 0.21297 | 0.81709 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.308 | 6.277 | 0.73501 | 1.00000 | |
RegenerationR2 | 0.465 | 6.277 | 0.08424 | 0.46579 | |
RegenerationR3 | 0.457 | 6.277 | 0.12049 | 0.53906 | |
RegenerationR4 | 0.068 | 6.277 | 0.82250 | 0.99511 | |
RegenerationR5 | 0.437 | 6.277 | 0.11666 | 0.51365 | |
RegenerationR6 | 0.881 | 6.277 | 0.00220 | 0.05333 | |
RegenerationBL | 1.148 | 6.277 | 0.00006 | 0.00299 | Specific for BL: 1.148 |
RegenerationTP | -0.142 | 6.277 | 0.69295 | 1.00000 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_49480 | 3325 | 69.28 | Mlig455_061462 | Neo: - Age: - Regeneration-upregulated BL: 1.148 Regeneration-enriched BL: 1.148 |
RBM39 | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_061462 {REF} {Length: 2374} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=136.6]; linker between RRM2 and RRM3 domains in RBM39 protein [PF15519.8, score=60.2]} {Human: ENSG00000131051, RBM39, RNA binding motif protein 39, [RH, Score=363, Expect=1e-118]} {Mouse: ENSMUSG00000027620, Rbm39, RNA binding motif protein 39, [RH, Score=363, Expect=9e-119]} {Dmel: FBgn0031883, Caper, [RH, Score=342, Expect=1e-109]} {Celegans: WBGene00021921, Y55F3AM.3, [RH, Score=258, Expect=6e-78]} {Smed: dd_Smed_v6_1932_0_1, dd_Smed_v6_1932_0_1, [RH, Score=276, Expect=2e-86]} {RNA1509_4239, RNA1509_43417, RNA1509_9704} {RNA1310_3908, RNA1509_4239, RNA1509_43417} {RNA1509_4239, RNA1509_43417, RNA815_1081.1} |
2. | MligTC455_49481 | 2896 | 60.33 | Mlig455_061474 | Neo: - Age: - Regeneration-upregulated BL: 1.088 Regeneration-enriched BL: 1.088 |
RBM39 | 5.568 | 0.995 | 0.984 | 0.805 | 0.989 | 0.989 | 0.806 | Mlig455_061474 {REF} {Length: 2417} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=137.4]; linker between RRM2 and RRM3 domains in RBM39 protein [PF15519.8, score=59.8]} {Human: ENSG00000131051, RBM39, RNA binding motif protein 39, [RH, Score=365, Expect=2e-119]} {Mouse: ENSMUSG00000027620, Rbm39, RNA binding motif protein 39, [RH, Score=365, Expect=1e-119]} {Dmel: FBgn0031883, Caper, [Score=342, Expect=6e-110]} {Celegans: WBGene00021921, Y55F3AM.3, [RH, Score=259, Expect=2e-78]} {Smed: dd_Smed_v6_1932_0_1, dd_Smed_v6_1932_0_1, [RH, Score=273, Expect=2e-85]} {RNA1509_9704} {RNA1310_3436.2, RNA1509_9704} {RNA1509_9704, RNA815_1081.1} |
3. | MligTC455_47256 | 1264 | 26.33 | Mlig455_035294 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.234 Region-enriched R4: 1.028/0.00756 |
FRG1 | 2.613 | - | - | - | 0.741 | 0.917 | 0.955 | Mlig455_035294 {REF} {Length: 1519} {TRANSSPLICED} {Pfam: FRG1-like domain [PF06229.14, score=186.6]; FAM32A [PF08555.12, score=20.3]} {Human: ENSG00000275145, FRG1, FSHD region gene 1, [RH, Score=208, Expect=2e-66]; ENSG00000283630, FRG1, FSHD region gene 1, [RH, Score=208, Expect=2e-66]; ENSG00000283153, FRG1, FSHD region gene 1, [RH, Score=208, Expect=2e-66]; ENSG00000109536, FRG1, FSHD region gene 1, [RH, Score=208, Expect=2e-66]} {Mouse: ENSMUSG00000031590, Frg1, FSHD region gene 1, [RH, Score=209, Expect=7e-67]} {Dmel: FBgn0036964, FRG1, FSHD region gene 1, [RH, Score=168, Expect=7e-51]} {Celegans: WBGene00014177, frg-1, Protein FRG1 homolog, [RH, Score=129, Expect=8e-36]} {Smed: dd_Smed_v6_3094_0_1, dd_Smed_v6_3094_0_1, [RH, Score=206, Expect=8e-66]} {RNA1509_13353, RNA1509_49322} {RNA1310_22014.1, RNA1509_13353, RNA1509_49322} {RNA1509_13353, RNA1509_49322, RNA815_8956} |
4. | MligTC455_38399 | 4980 | 103.75 | Mlig455_048481 | Neo: Int S/G2/M Age: - |
VCP | 0.99 | - | - | - | - | - | 0.990 | Mlig455_048481 {REF} {Length: 3323} {Pfam: ATPase family associated with various cellular activities (AAA) [PF00004.31, score=323.2]; AAA+ lid domain [PF17862.3, score=83.8]; Cell division protein 48 (CDC48), N-terminal domain [PF02359.20, score=75.5]; Holliday junction DNA helicase RuvB P-loop domain [PF05496.14, score=52.5]; AAA ATPase domain [PF13191.8, score=50.7]; AAA domain (Cdc48 subfamily) [PF07724.16, score=43.2]; AAA domain (dynein-related subfamily) [PF07728.16, score=41.5]; Cell division protein 48 (CDC48), domain 2 [PF02933.19, score=41.0]; AAA domain [PF13671.8, score=40.9]; Vps4 C terminal oligomerisation domain [PF09336.12, score=40.1]; AAA domain [PF13401.8, score=38.3]; TIP49 P-loop domain [PF06068.15, score=35.1]; AAA domain [PF13238.8, score=32.1]; RNA helicase [PF00910.24, score=31.2]; AAA domain [PF13173.8, score=29.7]; Magnesium chelatase, subunit ChlI [PF01078.23, score=29.0]; ABC transporter [PF00005.29, score=27.1]; IstB-like ATP binding protein [PF01695.19, score=27.1]; AAA domain [PF13521.8, score=27.0]; Parvovirus non-structural protein NS1 [PF01057.19, score=26.4]; P-loop containing dynein motor region [PF12775.9, score=26.1]; AAA domain [PF13207.8, score=25.5]; Bacterial dnaA protein [PF00308.20, score=24.8]; ATPase domain predominantly from Archaea [PF01637.20, score=24.3]; AAA domain [PF13481.8, score=23.5]; Threonylcarbamoyl adenosine biosynthesis protein TsaE [PF02367.19, score=23.1]; KaiC [PF06745.15, score=23.0]; AAA domain [PF13479.8, score=22.8]; Viral (Superfamily 1) RNA helicase [PF01443.20, score=22.2]; Sigma-54 interaction domain [PF00158.28, score=22.1]; NACHT domain [PF05729.14, score=21.1]; Zeta toxin [PF06414.14, score=21.1]; Protein of unknown function (DUF815) [PF05673.15, score=20.4]; Type III restriction enzyme, res subunit [PF04851.17, score=20.2]; NB-ARC domain [PF00931.24, score=20.0]; Sigma-54 interaction domain [PF14532.8, score=19.1]; ATPase family associated with various cellular activities (AAA) [PF07726.13, score=19.0]; Uncharacterized conserved protein (DUF2075) [PF09848.11, score=18.5]} {Human: ENSG00000165280, VCP, valosin containing protein, [RH, Score=1269, Expect=0.0]} {Mouse: ENSMUSG00000028452, Vcp, valosin containing protein, [RH, Score=1269, Expect=0.0]} {Dmel: FBgn0261014, TER94, [RH, Score=1271, Expect=0.0]} {Celegans: WBGene00008053, cdc-48.2, Transitional endoplasmic reticulum ATPase homolog 2, [RH, Score=1209, Expect=0.0]} {Smed: dd_Smed_v6_482_0_1, dd_Smed_v6_482_0_1, [RH, Score=1309, Expect=0.0]} {RNA1509_11640, RNA1509_13887, RNA1509_41889, RNA1509_514, RNA1509_8519} {RNA1310_4584, RNA1509_11640, RNA1509_13887, RNA1509_41889, RNA1509_514, RNA1509_8519} {RNA1509_11640, RNA1509_13887, RNA1509_41889, RNA1509_514, RNA1509_8519, RNA815_1672.2} |
5. | MligTC455_39871 | 1444 | 30.09 | Mlig455_029714, Mlig455_034857 | Neo: - Age: - |
STAU2 | 0.972 | - | - | - | 0.972 | - | - | Mlig455_029714 {REF} {Length: 2011} {Pfam: Staufen C-terminal domain [PF16482.7, score=27.1]; Double-stranded RNA binding motif [PF00035.28, score=19.5]} {RNA1509_53015} {RNA1310_4047.1} {RNA815_17208.1} Mlig455_034857 {REF} {Length: 3387} {TRANSSPLICED} {Pfam: Double-stranded RNA binding motif [PF00035.28, score=122.6]; Staufen C-terminal domain [PF16482.7, score=44.8]; double strand RNA binding domain from DEAD END PROTEIN 1 [PF14709.9, score=27.2]} {Human: ENSG00000040341, STAU2, staufen double-stranded RNA binding protein 2, [RH, Score=199, Expect=2e-54]} {Mouse: ENSMUSG00000025920, Stau2, staufen double-stranded RNA binding protein 2, [RH, Score=194, Expect=3e-53]} {Dmel: FBgn0003520, stau, staufen, [RH, Score=102, Expect=7e-22]} {Celegans: WBGene00018857, stau-1, STAUfen (DsRNA binding protein) homolog, [RH, Score=148, Expect=9e-37]} {RNA1509_18826, RNA1509_38637, RNA1509_42637, RNA1509_53015, RNA1509_55172, RNA1509_58024} {RNA1310_4047.1, RNA1509_18826, RNA1509_38637, RNA1509_42637, RNA1509_53015, RNA1509_55172, RNA1509_58024} {RNA1509_18826, RNA1509_38637, RNA1509_42637, RNA1509_53015, RNA1509_55172, RNA1509_58024, RNA815_4500} |
6. | MligTC455_42952 | 1133 | 23.6 | Mlig455_038557 | Neo: - Age: Down-Down-Down, logFC(26M/2M)=-0.656 Region-enriched R4: 1.639/0.00071 |
0.964 | - | - | - | 0.964 | - | - | Mlig455_038557 {REF} {Length: 1484} {TRANSSPLICED} {Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial [PF15880.7, score=40.2]} {RNA1509_10373} {RNA1310_14044.2, RNA1509_10373} {RNA1509_10373, RNA815_9326.1} | |
7. | MligTC455_44044 | 393 | 8.19 | Mlig455_068889 | Neo: Int S/G2/M Age: - Regeneration-upregulated BL: 2.803 Regeneration-enriched BL: 2.803 |
SNRPA | 0.958 | - | - | - | - | - | 0.958 | Mlig455_068889 {REF} {Length: 1007} {TRANSSPLICED} {Pfam: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF00076.24, score=85.0]; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) [PF13893.8, score=27.1]; Protein of unknown function (DUF4523) [PF15023.8, score=25.7]; Occluded RNA-recognition motif [PF16842.7, score=20.6]} {Human: ENSG00000077312, SNRPA, small nuclear ribonucleoprotein polypeptide A, [RH, Score=239, Expect=7e-79]} {Mouse: ENSMUSG00000061479, Snrpa, small nuclear ribonucleoprotein polypeptide A, [RH, Score=237, Expect=4e-78]} {Dmel: FBgn0003449, snf, sans fille, [RH, Score=221, Expect=7e-73]} {Celegans: WBGene00004385, rnp-2, RNP (RRM RNA binding domain) containing, [RH, Score=197, Expect=1e-63]} {Smed: dd_Smed_v6_2274_0_1, dd_Smed_v6_2274_0_1, [RH, Score=253, Expect=1e-85]} {RNA1509_35516, RNA1509_38471, RNA1509_5409} {RNA1310_9619, RNA1509_35516, RNA1509_38471, RNA1509_5409} {RNA1509_35516, RNA1509_38471, RNA1509_5409, RNA815_13424} |
8. | MligTC455_45486 | 487 | 10.14 | Mlig455_019746 | Neo: - Age: Down-Up-Up |
DLG2 | 0.956 | - | - | - | - | 0.956 | - | Mlig455_019746 {REF} {Length: 3340} {Pfam: Guanylate kinase [PF00625.23, score=164.7]; PDZ domain [PF00595.26, score=69.8]; PDZ domain [PF17820.3, score=37.7]; SH3 domain [PF00018.30, score=33.0]; Variant SH3 domain [PF07653.19, score=27.2]; PDZ domain [PF13180.8, score=22.1]; Variant SH3 domain [PF14604.8, score=20.5]; Procyclic acidic repetitive protein (PARP) [PF05887.13, score=19.1]} {Human: ENSG00000150672, DLG2, discs large MAGUK scaffold protein 2, [RH, Score=427, Expect=6e-141]} {Mouse: ENSMUSG00000052572, Dlg2, discs large MAGUK scaffold protein 2, [RH, Score=426, Expect=1e-140]} {Dmel: FBgn0001624, dlg1, discs large 1, [Score=434, Expect=1e-141]} {Celegans: WBGene00001006, dlg-1, Drosophila Discs LarGe homolog; MAGUK protein DLG-1; SAP97-like protein DLG-1, [RH, Score=343, Expect=9e-107]} {Smed: dd_Smed_v6_8511_0_1, dd_Smed_v6_8511_0_1, [RH, Score=317, Expect=2e-101]} {RNA1509_16120, RNA1509_26114} {RNA1310_2555.1, RNA1509_16120} {RNA1509_16120, RNA815_2319} |
9. | MligTC455_42882 | 1121 | 23.35 | Mlig455_018334 | Neo: - Age: - |
EEF2K | 0.955 | - | - | 0.955 | - | - | - | Mlig455_018334 {REF} {Length: 4963} {Pfam: Alpha-kinase family [PF02816.20, score=188.2]} {Human: ENSG00000103319, EEF2K, eukaryotic elongation factor 2 kinase, [Score=422, Expect=2e-135]; ENSG00000284161, EEF2K, eukaryotic elongation factor 2 kinase, [Score=420, Expect=1e-134]} {Mouse: ENSMUSG00000035064, Eef2k, eukaryotic elongation factor-2 kinase, [Score=416, Expect=8e-133]} {Celegans: WBGene00001160, efk-1, Eukaryotic elongation factor 2 kinase, [RH, Score=320, Expect=1e-96]} {Smed: dd_Smed_v6_9576_0_1, dd_Smed_v6_9576_0_1, [Score=401, Expect=3e-130]} {RNA1509_1554} {RNA1310_5135.1} {RNA815_1164.1} |
10. | MligTC455_12541 | 1229 | 25.6 | Mlig455_037225 | Neo: - Age: - |
ZFYVE1 | 0.953 | - | - | - | - | 0.953 | - | Mlig455_037225 {REF} {Length: 2985} {TRANSSPLICED} {Pfam: FYVE zinc finger [PF01363.23, score=89.3]} {Human: ENSG00000165861, ZFYVE1, zinc finger FYVE-type containing 1, [RH, Score=552, Expect=0.0]} {Mouse: ENSMUSG00000042628, Zfyve1, zinc finger, FYVE domain containing 1, [RH, Score=547, Expect=0.0]} {Dmel: FBgn0039492, CG6051, [Score=60.1, Expect=5e-09]} {Celegans: WBGene00003084, lst-2, Lateral signaling target protein 2, [Score=65.5, Expect=6e-11]} {Smed: dd_Smed_v6_7922_0_1, dd_Smed_v6_7922_0_1, [RH, Score=387, Expect=5e-125]} {RNA1509_11257, RNA1509_55322} {RNA1310_5567, RNA1509_11257, RNA1509_55322} {RNA1509_11257, RNA1509_55322, RNA815_840.1} |
11. | MligTC455_44854 | 1026 | 21.38 | Mlig455_021934 | Neo: - Age: - Region-enriched R5: 1.051/0.00690 |
RNF217 | 0.952 | - | - | - | 0.952 | - | - | Mlig455_021934 {REF} {Length: 2682} {Pfam: IBR domain, a half RING-finger domain [PF01485.23, score=56.5]} {Human: ENSG00000146373, RNF217, ring finger protein 217, [Score=172, Expect=6e-46]} {Mouse: ENSMUSG00000063760, Rnf217, ring finger protein 217, [Score=170, Expect=1e-45]} {Dmel: FBgn0025186, ari-2, ariadne 2, [Score=72.8, Expect=3e-13]} {Celegans: WBGene00013270, Y57A10A.31, [Score=78.6, Expect=8e-15]} {Smed: dd_Smed_v6_7110_0_1, dd_Smed_v6_7110_0_1, [Score=135, Expect=2e-33]} {RNA1509_38984, RNA1509_4132} {RNA1310_7549, RNA1509_38984} {RNA1509_38984, RNA815_2398.1} |
12. | MligTC455_39898 | 738 | 15.38 | Mlig455_030521 | Neo: Irradiation Age: - Region-enriched R4: 2.375/0.00002 |
ZNF569 | 0.951 | - | - | - | - | - | 0.951 | Mlig455_030521 {REF} {Length: 2607} {TRANSSPLICED} {Pfam: Zinc-finger double domain [PF13465.8, score=113.0]; Zinc finger, C2H2 type [PF00096.28, score=73.4]; C2H2-type zinc finger [PF13894.8, score=62.0]; Zinc-finger of C2H2 type [PF12874.9, score=25.8]; C2H2-type zinc finger [PF13912.8, score=22.8]; zinc-finger of a C2HC-type [PF13913.8, score=22.2]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=21.9]} {Human: ENSG00000196437, ZNF569, zinc finger protein 569, [Score=167, Expect=2e-44]; ENSG00000278129, ZNF8, zinc finger protein 8, [Score=167, Expect=5e-45]; ENSG00000160961, ZNF333, zinc finger protein 333, [Score=166, Expect=4e-44]; ENSG00000171827, ZNF570, zinc finger protein 570, [Score=164, Expect=6e-44]; ENSG00000130182, ZSCAN10, zinc finger and SCAN domain containing 10, [Score=163, Expect=2e-43]; ENSG00000188321, ZNF559, zinc finger protein 559, [Score=162, Expect=3e-43]; ENSG00000175691, ZNF77, zinc finger protein 77, [Score=162, Expect=3e-43]; ENSG00000187801, ZFP69B, ZFP69 zinc finger protein B, [Score=162, Expect=1e-43]; ENSG00000182318, ZSCAN22, zinc finger and SCAN domain containing 22, [Score=160, Expect=5e-43]; ENSG00000172006, ZNF554, zinc finger protein 554, [Score=160, Expect=8e-43]; ENSG00000189042, ZNF567, zinc finger protein 567, [Score=159, Expect=6e-42]; ENSG00000159917, ZNF235, zinc finger protein 235, [Score=159, Expect=1e-41]; ENSG00000274349, ZNF658, zinc finger protein 658, [Score=159, Expect=5e-41]; ENSG00000167384, ZNF180, zinc finger protein 180, [Score=159, Expect=9e-42]; ENSG00000268696, ZNF723, zinc finger protein 723, [Score=159, Expect=1e-42]; ENSG00000170100, ZNF778, zinc finger protein 778, [Score=159, Expect=1e-41]; ENSG00000196597, ZNF782, zinc finger protein 782, [Score=159, Expect=1e-41]; ENSG00000198440, ZNF583, zinc finger protein 583, [Score=159, Expect=5e-42]} {Mouse: ENSMUSG00000045519, Zfp560, zinc finger protein 560, [Score=170, Expect=2e-45]; ENSMUSG00000066880, Zfp617, zinc finger protein 617, [Score=169, Expect=5e-46]; ENSMUSG00000059975, Zfp74, zinc finger protein 74, [Score=167, Expect=2e-44]; ENSMUSG00000032425, Zfp949, zinc finger protein 949, [Score=166, Expect=1e-44]; ENSMUSG00000064141, Zfp69, zinc finger protein 69, [Score=165, Expect=3e-44]; ENSMUSG00000060397, Zfp128, zinc finger protein 128, [Score=165, Expect=2e-44]; ENSMUSG00000031079, Zfp300, zinc finger protein 300, [Score=164, Expect=7e-44]; ENSMUSG00000068962, Zfp114, zinc finger protein 114, [Score=163, Expect=1e-43]; ENSMUSG00000022526, Zfp251, zinc finger protein 251, [Score=162, Expect=4e-43]; ENSMUSG00000060510, Zfp266, zinc finger protein 266, [Score=162, Expect=3e-43]; ENSMUSG00000063108, Zfp26, zinc finger protein 26, [Score=162, Expect=2e-42]; ENSMUSG00000091474, 2610021A01Rik, RIKEN cDNA 2610021A01 gene, [Score=162, Expect=1e-42]} {Dmel: FBgn0038301, CG6654, [Score=159, Expect=3e-42]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [Score=137, Expect=1e-37]} {Smed: dd_Smed_v6_26394_0_1, dd_Smed_v6_26394_0_1, [Score=141, Expect=4e-39]} {RNA1509_12331, RNA1509_18316, RNA1509_37936} {RNA1310_8262, RNA1509_12331, RNA1509_18316, RNA1509_37936} {RNA1509_12331, RNA1509_18316, RNA1509_37936, RNA815_4306.2} |