Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Annotation |
---|---|---|---|---|---|---|
MligTC455_51318 | 370 | 7.71 | Mlig455_040327 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.854 Region-enriched R5: 1.980/0.00436 |
RAD51C | Mlig455_040327 {REF} {Length: 1394} {Pfam: Rad51 [PF08423.13, score=138.5]; AAA domain [PF13481.8, score=35.5]; KaiC [PF06745.15, score=18.8]} {Human: ENSG00000108384, RAD51C, RAD51 paralog C, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000007646, Rad51c, RAD51 paralog C, [RH, Score=181, Expect=4e-53]} {Dmel: FBgn0003482, spn-D, spindle D, [RH, Score=110, Expect=1e-27]} {Celegans: WBGene00004297, rad-51, RAD51 short isoform; RecA/Rad51/Dmc1-like protein, [Score=70.1, Expect=4e-13]} {Smed: dd_Smed_v6_16724_0_2, dd_Smed_v6_16724_0_2, [RH, Score=184, Expect=2e-55]} {RNA1509_27617} {RNA1310_25633.1} {RNA815_20829} |
Region | logFC | logCPM | Pvalue | FDR | Specificity |
---|---|---|---|---|---|
RegionR1 | -6.414 | 3.492 | 0.09174 | 0.65095 | |
RegionR2 | 0.617 | 3.492 | 0.52307 | 0.89644 | |
RegionR3 | 0.663 | 3.492 | 0.45376 | 0.96484 | |
RegionR4 | 1.757 | 3.492 | 0.01094 | 0.06528 | |
RegionR5 | 1.98 | 3.492 | 0.00034 | 0.00436 | |
RegionR6 | 0.607 | 3.492 | 0.50185 | 1.00000 | |
RegionR7 | -0.877 | 3.492 | 0.98283 | 1.00000 | |
RegionR8 | 1.667 | 3.492 | 0.10435 | 0.60327 |
Region | logFC | logCPM | PValue | FDR | Specificity |
---|---|---|---|---|---|
RegenerationR1 | -0.013 | 3.492 | 0.99998 | 1.00000 | |
RegenerationR2 | 0.407 | 3.492 | 0.37081 | 0.79646 | |
RegenerationR3 | 0.575 | 3.492 | 0.25207 | 0.68640 | |
RegenerationR4 | 0.277 | 3.492 | 0.54901 | 0.89227 | |
RegenerationR5 | -0.633 | 3.492 | 0.12372 | 0.52627 | |
RegenerationR6 | 0.808 | 3.492 | 0.11386 | 0.41567 | |
RegenerationBL | 0.089 | 3.492 | 0.90116 | 1.00000 | |
RegenerationTP | 0.495 | 3.492 | 0.53273 | 0.92258 |
Nr. | Cluster | Total UMI counts | Global CPM | Transcripts | Categories | Human homolog | Σ Spearman correlations | Int1 | Int2 | Int3 | Reg1 | Reg2 | Reg3 | Annotation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | MligTC455_51318 | 370 | 7.71 | Mlig455_040327 | Neo: Int S/G2/M Age: logFC(26M/2M)=0.854 Region-enriched R5: 1.980/0.00436 |
RAD51C | 6 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | Mlig455_040327 {REF} {Length: 1394} {Pfam: Rad51 [PF08423.13, score=138.5]; AAA domain [PF13481.8, score=35.5]; KaiC [PF06745.15, score=18.8]} {Human: ENSG00000108384, RAD51C, RAD51 paralog C, [RH, Score=183, Expect=1e-53]} {Mouse: ENSMUSG00000007646, Rad51c, RAD51 paralog C, [RH, Score=181, Expect=4e-53]} {Dmel: FBgn0003482, spn-D, spindle D, [RH, Score=110, Expect=1e-27]} {Celegans: WBGene00004297, rad-51, RAD51 short isoform; RecA/Rad51/Dmc1-like protein, [Score=70.1, Expect=4e-13]} {Smed: dd_Smed_v6_16724_0_2, dd_Smed_v6_16724_0_2, [RH, Score=184, Expect=2e-55]} {RNA1509_27617} {RNA1310_25633.1} {RNA815_20829} |
2. | MligTC455_28834 | 768 | 15.99 | Mlig455_025128 | Neo: - Age: - |
GARS | 1.838 | - | 0.964 | - | 0.874 | - | - | Mlig455_025128 {REF} {Length: 1771} {Pfam: Anticodon binding domain [PF03129.22, score=52.5]; tRNA synthetase class II core domain (G, H, P, S and T) [PF00587.27, score=44.1]} {Human: ENSG00000106105, GARS, glycyl-tRNA synthetase, [Score=366, Expect=7e-118]} {Mouse: ENSMUSG00000029777, Gars, glycyl-tRNA synthetase, [Score=367, Expect=2e-118]} {Dmel: FBgn0027088, GlyRS, Glycyl-tRNA synthetase, [Score=380, Expect=2e-124]} {Celegans: WBGene00001744, gars-1, Glycine--tRNA ligase, [Score=368, Expect=1e-119]} {Smed: dd_Smed_v6_3958_0_1, dd_Smed_v6_3958_0_1, [Score=359, Expect=3e-117]} {RNA1509_13579} {RNA1310_564} {RNA815_3927} |
3. | MligTC455_19831 | 411 | 8.56 | Mlig455_021736 | Neo: - Age: logFC(26M/2M)=0.431 Region-enriched R5: 2.122/0.01672 |
ALKBH6 | 1.799 | 0.847 | - | - | 0.952 | - | - | Mlig455_021736 {REF} {Length: 900} {TRANSSPLICED} {Pfam: 2OG-Fe(II) oxygenase superfamily [PF13532.8, score=47.2]} {Human: ENSG00000239382, ALKBH6, alkB homolog 6, [RH, Score=219, Expect=5e-71]} {Mouse: ENSMUSG00000042831, Alkbh6, alkB homolog 6, [RH, Score=227, Expect=3e-74]} {Dmel: FBgn0032259, CG6144, [RH, Score=190, Expect=3e-60]} {Celegans: WBGene00007202, B0564.2, [RH, Score=175, Expect=2e-54]} {Smed: dd_Smed_v6_20520_0_1, dd_Smed_v6_20520_0_1, [RH, Score=200, Expect=3e-64]} {RNA1310_40810} {RNA815_23286} |
4. | MligTC455_44211 | 452 | 9.41 | Mlig455_009049 | Neo: Int S/G2/M Age: - |
1.744 | - | 0.960 | - | - | - | 0.784 | Mlig455_009049 {REF} {Length: 1286} {TRANSSPLICED} {Pfam: RFX5 N-terminal domain [PF18326.3, score=25.0]} {RNA1509_27379} {RNA1310_26623, RNA1509_27379} {RNA1509_27379, RNA815_11463} | |
5. | MligTC455_17799 | 910 | 18.96 | Mlig455_039410 | Neo: Int S/G2/M Age: Down-Up-Up |
SARS2 | 1.711 | 0.760 | - | - | - | 0.951 | - | Mlig455_039410 {REF} {Length: 1953} {TRANSSPLICED} {Pfam: tRNA synthetase class II core domain (G, H, P, S and T) [PF00587.27, score=66.8]; Pre-rRNA-processing protein TSR2 [PF10273.11, score=63.1]} {Human: ENSG00000283104, SARS2, seryl-tRNA synthetase 2, mitochondrial, [RH, Score=244, Expect=5e-73]; ENSG00000104835, SARS2, seryl-tRNA synthetase 2, mitochondrial, [RH, Score=244, Expect=5e-73]; ENSG00000269547, AC011455.2, novel protein, [RH, Score=243, Expect=4e-72]; ENSG00000282835, AC011455.3, novel protein, [RH, Score=243, Expect=4e-72]} {Mouse: ENSMUSG00000070699, Sars2, seryl-aminoacyl-tRNA synthetase 2, [RH, Score=247, Expect=3e-74]} {Dmel: FBgn0021750, SerRS-m, Seryl-tRNA synthetase, mitochondrial, [RH, Score=233, Expect=2e-70]} {Celegans: WBGene00005662, sars-2, Seryl Amino-acyl tRNA Synthetase; Seryl-tRNA synthetase, [RH, Score=223, Expect=2e-66]} {Smed: dd_Smed_v6_9202_0_1, dd_Smed_v6_9202_0_1, [RH, Score=252, Expect=6e-78]} {RNA1509_14477, RNA1509_32857} {RNA1310_19261, RNA1509_14477, RNA1509_32857} {RNA1509_14477, RNA1509_32857, RNA815_14133} |
6. | MligTC455_44784 | 318 | 6.63 | Mlig455_053700 | Neo: - Age: - |
MKRN1 | 0.977 | - | - | - | 0.977 | - | - | Mlig455_053700 {REF} {Length: 2828} {TRANSSPLICED} {Pfam: Torus domain [PF16131.7, score=53.0]; CHY zinc finger [PF05495.14, score=51.1]; Zinc finger domain [PF18345.3, score=49.0]; Zinc finger C-x8-C-x5-C-x3-H type (and similar) [PF00642.26, score=44.5]; CCCH-type zinc finger [PF18044.3, score=34.5]; Zinc-finger containing family [PF15663.7, score=19.6]} {Human: ENSG00000133606, MKRN1, makorin ring finger protein 1, [RH, Score=47.0, Expect=5e-06]} {Mouse: ENSMUSG00000029922, Mkrn1, makorin, ring finger protein, 1, [Score=47.8, Expect=8e-06]} {RNA1509_13070} {RNA1310_6209} {RNA815_10322} |
7. | MligTC455_48056 | 184 | 3.83 | Mlig455_048769 | Neo: - Age: Up-Down-Down |
0.964 | - | - | - | - | - | 0.964 | Mlig455_048769 {REF} {Length: 7379} {TRANSSPLICED} {Pfam: PX domain [PF00787.26, score=33.3]} {RNA1509_29567, RNA1509_33291} {RNA1310_923.1, RNA1509_29567} {RNA1509_29567, RNA815_1595} | |
8. | MligTC455_33018 | 540 | 11.25 | Mlig455_065016 | Neo: Int S/G2/M Age: - |
SLX4 | 0.96 | - | - | - | - | 0.960 | - | Mlig455_065016 {REF} {Length: 3818} {TRANSSPLICED} {Human: ENSG00000188827, SLX4, SLX4 structure-specific endonuclease subunit, [RH, Score=53.5, Expect=1e-06]} {Mouse: ENSMUSG00000039738, Slx4, SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae), [Score=50.1, Expect=1e-05]} {RNA1509_23641, RNA1509_23757} {RNA1310_6766, RNA1509_23641, RNA1509_23757} {RNA1509_23641, RNA1509_23757, RNA815_4724} |
9. | MligTC455_32126 | 504 | 10.51 | Mlig455_002779, Mlig455_066933 | Neo: Int S/G2/M Age: - Region-enriched R5: 1.758/0.00025 |
TRIM31 | 0.958 | - | 0.958 | - | - | - | - | Mlig455_002779 {REF} {Length: 3847} {TRANSSPLICED} {Pfam: zinc finger of C3HC4-type, RING [PF15227.8, score=38.3]; RING-type zinc-finger [PF13445.8, score=36.2]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=32.8]; Prokaryotic RING finger family 4 [PF14447.8, score=32.3]; Ring finger domain [PF13639.8, score=28.8]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=27.8]; zinc-RING finger domain [PF14634.8, score=27.5]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=22.5]} {Human: ENSG00000223531, TRIM31, tripartite motif containing 31, [RH, Score=58.9, Expect=9e-09]; ENSG00000204616, TRIM31, tripartite motif containing 31, [RH, Score=58.9, Expect=9e-09]; ENSG00000233573, TRIM31, tripartite motif containing 31, [RH, Score=58.9, Expect=9e-09]; ENSG00000224168, TRIM31, tripartite motif containing 31, [RH, Score=58.9, Expect=9e-09]; ENSG00000225130, TRIM31, tripartite motif containing 31, [RH, Score=58.9, Expect=9e-09]; ENSG00000226402, TRIM31, tripartite motif containing 31, [RH, Score=58.9, Expect=9e-09]; ENSG00000137397, TRIM31, tripartite motif containing 31, [RH, Score=58.2, Expect=2e-08]; ENSG00000224542, TRIM31, tripartite motif containing 31, [RH, Score=57.0, Expect=1e-08]} {Mouse: ENSMUSG00000058063, Trim31, tripartite motif-containing 31, [RH, Score=53.5, Expect=4e-07]} {Dmel: FBgn0036897, CG8786, [Score=53.9, Expect=2e-07]} {Smed: dd_Smed_v6_6290_0_1, dd_Smed_v6_6290_0_1, [Score=50.4, Expect=1e-06]} {RNA1509_21799} {RNA1310_16610, RNA1509_21799} {RNA1509_21799, RNA815_19239} Mlig455_066933 {REF} {Length: 3550} {TRANSSPLICED} {Pfam: zinc finger of C3HC4-type, RING [PF15227.8, score=38.6]; RING-type zinc-finger [PF13445.8, score=36.5]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=33.1]; Prokaryotic RING finger family 4 [PF14447.8, score=32.8]; Ring finger domain [PF13639.8, score=29.1]; Zinc finger, C3HC4 type (RING finger) [PF00097.27, score=28.1]; zinc-RING finger domain [PF14634.8, score=27.8]; Zinc finger, C3HC4 type (RING finger) [PF13923.8, score=22.8]} {Human: ENSG00000233573, TRIM31, tripartite motif containing 31, [RH, Score=63.5, Expect=3e-10]; ENSG00000226402, TRIM31, tripartite motif containing 31, [RH, Score=63.5, Expect=3e-10]; ENSG00000224168, TRIM31, tripartite motif containing 31, [RH, Score=63.2, Expect=3e-10]; ENSG00000223531, TRIM31, tripartite motif containing 31, [RH, Score=63.2, Expect=3e-10]; ENSG00000204616, TRIM31, tripartite motif containing 31, [RH, Score=63.2, Expect=3e-10]; ENSG00000225130, TRIM31, tripartite motif containing 31, [RH, Score=63.2, Expect=3e-10]; ENSG00000137397, TRIM31, tripartite motif containing 31, [RH, Score=62.8, Expect=5e-10]; ENSG00000224542, TRIM31, tripartite motif containing 31, [RH, Score=61.2, Expect=5e-10]} {Mouse: ENSMUSG00000058063, Trim31, tripartite motif-containing 31, [RH, Score=53.5, Expect=3e-07]} {Dmel: FBgn0036897, CG8786, [Score=53.5, Expect=2e-07]} {Smed: dd_Smed_v6_6290_0_1, dd_Smed_v6_6290_0_1, [Score=50.4, Expect=1e-06]} {RNA1509_47313, RNA1509_48965} {RNA1310_43552, RNA1509_47313, RNA1509_48965} {RNA1509_47313, RNA1509_48965, RNA815_19239} |
10. | MligTC455_35412 | 78 | 1.63 | Mlig455_064234 | Neo: - Age: logFC(26M/2M)=-0.522 Region-enriched R4: 5.694/0.00671 |
PPP3CA | 0.958 | - | - | - | - | 0.958 | - | Mlig455_064234 {REF} {Length: 1945} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=130.1]} {Human: ENSG00000138814, PPP3CA, protein phosphatase 3 catalytic subunit alpha, [Score=684, Expect=0.0]; ENSG00000107758, PPP3CB, protein phosphatase 3 catalytic subunit beta, [Score=672, Expect=0.0]; ENSG00000120910, PPP3CC, protein phosphatase 3 catalytic subunit gamma, [Score=663, Expect=0.0]} {Mouse: ENSMUSG00000028161, Ppp3ca, protein phosphatase 3, catalytic subunit, alpha isoform, [Score=686, Expect=0.0]; ENSMUSG00000021816, Ppp3cb, protein phosphatase 3, catalytic subunit, beta isoform, [Score=673, Expect=0.0]; ENSMUSG00000022092, Ppp3cc, protein phosphatase 3, catalytic subunit, gamma isoform, [Score=653, Expect=0.0]} {Dmel: FBgn0267912, CanA-14F, Calcineurin A at 14F, [Score=681, Expect=0.0]} {Celegans: WBGene00006527, tax-6, Serine/threonine-protein phosphatase 2B catalytic subunit, [RH, Score=650, Expect=0.0]} {Smed: dd_Smed_v6_9037_0_1, dd_Smed_v6_9037_0_1, [RH, Score=596, Expect=0.0]} {RNA1509_53749} {RNA1310_17931} {RNA815_6996} |
11. | MligTC455_30110 | 326 | 6.78 | Mlig455_048850 | Neo: - Age: - |
0.956 | - | - | - | - | - | 0.956 | Mlig455_048850 {REF} {Length: 3264} {TRANSSPLICED} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=63.1]} {Smed: dd_Smed_v6_26484_0_6, dd_Smed_v6_26484_0_6, [Score=46.6, Expect=1e-06]} {RNA1509_9107} {RNA1310_13804} {RNA815_857.1} | |
12. | MligTC455_46787 | 272 | 5.66 | Mlig455_000093 | Neo: - Age: - |
AMD1 | 0.956 | - | - | - | - | - | 0.956 | Mlig455_000093 {REF} {Length: 3250} {Pfam: Adenosylmethionine decarboxylase [PF01536.18, score=306.3]} {Human: ENSG00000123505, AMD1, adenosylmethionine decarboxylase 1, [RH, Score=197, Expect=3e-59]} {Mouse: ENSMUSG00000075232, Amd1, S-adenosylmethionine decarboxylase 1, [RH, Score=199, Expect=3e-60]; ENSMUSG00000063953, Amd2, S-adenosylmethionine decarboxylase 2, [RH, Score=199, Expect=3e-60]} {Dmel: FBgn0019932, SamDC, S-adenosylmethionine decarboxylase, [RH, Score=199, Expect=5e-60]} {Celegans: WBGene00004875, smd-1, S-adenosylmethionine decarboxylase proenzyme S-adenosylmethionine decarboxylase alpha chain S-adenosylmethionine decarboxylase beta chain, [RH, Score=185, Expect=9e-55]} {Smed: dd_Smed_v6_1099_0_1, dd_Smed_v6_1099_0_1, [RH, Score=223, Expect=6e-70]} {RNA1509_15722, RNA1509_27028, RNA1509_34880, RNA1509_37988, RNA1509_48779} {RNA1310_23720, RNA1509_15722, RNA1509_27028, RNA1509_34880, RNA1509_37988, RNA1509_48779} {RNA1509_15722, RNA1509_27028, RNA1509_34880, RNA1509_37988, RNA1509_48779, RNA815_9640} |
13. | MligTC455_22877 | 121 | 2.53 | Mlig455_052516 | Neo: - |
RAB6A | 0.955 | - | 0.955 | - | - | - | - | Mlig455_052516 {REF} {Length: 1141} {TRANSSPLICED} {Pfam: Ras family [PF00071.24, score=195.9]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=122.5]; ADP-ribosylation factor family [PF00025.23, score=50.5]; Signal recognition particle receptor beta subunit [PF09439.12, score=26.7]; 50S ribosome-binding GTPase [PF01926.25, score=24.7]; Elongation factor Tu GTP binding domain [PF00009.29, score=23.9]; RsgA GTPase [PF03193.18, score=21.9]; Ferrous iron transport protein B [PF02421.20, score=21.7]} {Human: ENSG00000175582, RAB6A, RAB6A, member RAS oncogene family, [Score=324, Expect=1e-113]; ENSG00000154917, RAB6B, RAB6B, member RAS oncogene family, [Score=322, Expect=4e-113]} {Mouse: ENSMUSG00000030704, Rab6a, RAB6A, member RAS oncogene family, [Score=324, Expect=7e-114]; ENSMUSG00000032549, Rab6b, RAB6B, member RAS oncogene family, [Score=322, Expect=3e-113]} {Dmel: FBgn0015797, Rab6, [Score=328, Expect=1e-115]} {Celegans: WBGene00004269, rab-6.1, Ras-related protein Rab-6.1, [RH, Score=311, Expect=3e-109]} {Smed: dd_Smed_v6_4465_0_1, dd_Smed_v6_4465_0_1, [Score=330, Expect=7e-117]} {RNA1509_20446} {RNA1310_4872.1} {RNA815_3219.2} |
14. | MligTC455_49283 | 671 | 13.99 | Mlig455_001528, Mlig455_046576 | Neo: Int S/G2/M Age: - Region-enriched R2: 1.859/0.02944 |
MMACHC | 0.953 | - | 0.953 | - | - | - | - | Mlig455_001528 {REF} {Length: 1838} {TRANSSPLICED} {Pfam: Methylmalonic aciduria and homocystinuria type C family [PF16690.7, score=156.7]} {Human: ENSG00000132763, MMACHC, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria, [RH, Score=130, Expect=1e-35]} {Mouse: ENSMUSG00000028690, Mmachc, methylmalonic aciduria cblC type, with homocystinuria, [RH, Score=130, Expect=4e-36]} {Smed: dd_Smed_v6_8584_0_1, dd_Smed_v6_8584_0_1, [RH, Score=114, Expect=3e-30]} {RNA1509_29990, RNA1509_42294} {RNA1310_36622, RNA1509_29990, RNA1509_42294} {RNA1509_29990, RNA1509_42294, RNA815_18456} Mlig455_046576 {REF} {Length: 1840} {TRANSSPLICED} {Pfam: Methylmalonic aciduria and homocystinuria type C family [PF16690.7, score=157.4]} {Human: ENSG00000132763, MMACHC, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria, [RH, Score=132, Expect=2e-36]} {Mouse: ENSMUSG00000028690, Mmachc, methylmalonic aciduria cblC type, with homocystinuria, [RH, Score=132, Expect=6e-37]} {Smed: dd_Smed_v6_8584_0_1, dd_Smed_v6_8584_0_1, [RH, Score=114, Expect=6e-30]} {RNA1509_29990, RNA1509_35509, RNA1509_39634} {RNA1310_36622, RNA1509_35509, RNA1509_39634} {RNA1509_35509, RNA1509_39634, RNA815_18456} |