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Results for MligTC455_53231

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_53231 3817 79.52 Mlig455_029524

Neo: -

Age: -

Region-enriched R8: 1.875/0.00000
Region-enriched R7: 1.263/0.00050

Regeneration-depleted BL: -2.126
Regeneration-depleted TP: -1.952

PKD2 Mlig455_029524 {REF} {Length: 3383} {Pfam: Polycystin cation channel [PF08016.14, score=469.8]; Ion transport protein [PF00520.33, score=89.9]; EF hand [PF00036.34, score=29.0]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=19.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=731, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=732, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=310, Expect=5e-92]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=363, Expect=5e-114]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=748, Expect=0.0]} {RNA1509_54167} {RNA1310_10884} {RNA815_4012.1}

Cumulative graph for MligTC455_53231

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -0.032 6.309 0.95605 1.00000
RegionR2 0.797 6.309 0.01242 0.11543
RegionR3 -0.924 6.309 0.00258 0.06012
RegionR4 -0.84 6.309 0.01822 0.09535
RegionR5 -1.395 6.309 0.00001 0.00017
RegionR6 -0.743 6.309 0.01354 0.20229
RegionR7 1.263 6.309 0.00001 0.00050
RegionR8 1.875 6.309 0.00000 0.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.12 6.309 0.87734 1.00000
RegenerationR2 0.06 6.309 0.86195 1.00000
RegenerationR3 -0.372 6.309 0.31613 0.74569
RegenerationR4 -0.828 6.309 0.03013 0.28041
RegenerationR5 -0.268 6.309 0.47142 0.84245
RegenerationR6 -0.711 6.309 0.06505 0.32045
RegenerationBL -2.126 6.309 0.00000 0.00001
RegenerationTP -1.952 6.309 0.00000 0.00017


Genes with expression patterns similar to MligTC455_53231

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_53231 3817 79.52 Mlig455_029524

Neo: -

Age: -

Region-enriched R8: 1.875/0.00000
Region-enriched R7: 1.263/0.00050

Regeneration-depleted BL: -2.126
Regeneration-depleted TP: -1.952

PKD2 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_029524 {REF} {Length: 3383} {Pfam: Polycystin cation channel [PF08016.14, score=469.8]; Ion transport protein [PF00520.33, score=89.9]; EF hand [PF00036.34, score=29.0]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=19.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=731, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=732, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=310, Expect=5e-92]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=363, Expect=5e-114]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=748, Expect=0.0]} {RNA1509_54167} {RNA1310_10884} {RNA815_4012.1}
2. MligTC455_53232 3932 81.91 Mlig455_043077

Neo: -

Age: -

Region-enriched R8: 1.891/0.00000
Region-enriched R7: 1.329/0.00017

Regeneration-depleted BL: -2.128
Regeneration-depleted TP: -2.052

PKD2 5.987 0.997 0.993 0.998 1.000 0.999 1.000 Mlig455_043077 {REF} {Length: 3380} {Pfam: Polycystin cation channel [PF08016.14, score=472.5]; Ion transport protein [PF00520.33, score=89.3]; EF hand [PF00036.34, score=29.1]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=19.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [Score=733, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=733, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=310, Expect=8e-92]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=363, Expect=4e-114]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [RH, Score=744, Expect=0.0]} {RNA1509_54167} {RNA1310_10884, RNA1509_54167} {RNA1509_54167, RNA815_4012.1}
3. MligTC455_53721 868 18.09 Mlig455_025205

Neo: -

Age: Down-Up-Up

Region-enriched R2: 1.531/0.01572

5.25 0.843 0.831 0.869 0.955 0.885 0.867 Mlig455_025205 {REF} {Length: 1174} {Pfam: Sel1 repeat [PF08238.14, score=31.9]} {Smed: dd_Smed_v6_9387_0_1, dd_Smed_v6_9387_0_1, [RH, Score=194, Expect=2e-62]} {RNA1509_19616} {RNA1310_29567} {RNA815_13742}
4. MligTC455_42994 1521 31.7 Mlig455_035840

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=0.356

Region-enriched R2: 1.854/0.00052

4.488 - 0.830 0.897 0.889 0.959 0.913 Mlig455_035840 {REF} {Length: 1436} {RNA1509_29485, RNA1509_42231} {RNA1310_26640, RNA1509_29485, RNA1509_42231} {RNA1509_29485, RNA1509_42231, RNA815_37260}
5. MligTC455_26766 638 13.3 Mlig455_017977

Neo: -

Age: Up-Down-Down

Region-specific R2: 4.360

Region-enriched R2: 3.395/0.00052

4.46 - 0.723 0.879 0.958 0.987 0.913 Mlig455_017977 {REF} {Length: 2516} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [Score=249, Expect=3e-71]} {RNA1509_19813} {RNA1310_621} {RNA815_183.1}
6. MligTC455_26765 686 14.29 Mlig455_006971

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.201/0.00046

4.448 - 0.718 0.878 0.954 0.986 0.912 Mlig455_006971 {REF} {Length: 6360} {Pfam: Cadherin domain [PF00028.19, score=29.2]} {Smed: dd_Smed_v6_10627_0_1, dd_Smed_v6_10627_0_1, [RH, Score=328, Expect=1e-93]} {RNA1509_19813, RNA1509_5311} {RNA1310_621, RNA1509_19813, RNA1509_5311} {RNA1509_19813, RNA1509_5311, RNA815_183.1}
7. MligTC455_14904 4225 88.01 Mlig455_037596

Neo: -

Age: logFC(26M/2M)=0.385

Region-enriched R8: 1.541/0.00053

4.422 0.813 0.932 0.951 - 0.826 0.900 Mlig455_037596 {REF} {Length: 2914} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=59.3, Expect=3e-09]} {RNA1509_17730, RNA1509_4337} {RNA1310_7259, RNA1509_17730} {RNA1509_17730, RNA815_206}
8. MligTC455_14903 1751 36.49 Mlig455_037514

Neo: -

Age: -

Region-enriched R8: 1.893/0.00470

4.418 0.895 0.786 0.954 - 0.902 0.881 Mlig455_037514 {REF} {Length: 2886} {Dmel: FBgn0034294, Muc55B, Mucin 55B, [Score=58.5, Expect=6e-09]} {Celegans: WBGene00008194, C49C3.4, [Score=51.2, Expect=1e-06]} {RNA1509_4337} {RNA1310_7259} {RNA815_206}
9. MligTC455_42037 1931 40.23 Mlig455_063391

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.444

Region-specific R2: 2.479

Region-enriched R2: 1.442/0.00136

4.409 0.861 0.789 0.906 - 0.984 0.869 Mlig455_063391 {REF} {Length: 1482} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1310_24553, RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236} {RNA1509_22218, RNA1509_26529, RNA1509_28020, RNA1509_35236, RNA815_11766}
10. MligTC455_33039 312 6.51 Mlig455_032494

Neo: -

Age: Up-Down-Down

Region-enriched R2: 3.545/0.00267

PKDREJ 4.339 - 0.835 0.887 0.757 0.969 0.891 Mlig455_032494 {REF} {Length: 11952} {Pfam: Polycystin cation channel [PF08016.14, score=289.9]; REJ domain [PF02010.17, score=90.4]; PLAT/LH2 domain [PF01477.25, score=68.4]; PKD domain [PF00801.22, score=57.9]; PKD domain [PF18911.2, score=36.7]; Ion transport protein [PF00520.33, score=36.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=30.0]; WSC domain [PF01822.21, score=23.3]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=267, Expect=1e-70]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=292, Expect=3e-78]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=136, Expect=2e-31]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=297, Expect=4e-80]} {Smed: dd_Smed_v6_15525_0_1, dd_Smed_v6_15525_0_1, [Score=1504, Expect=0.0]} {RNA1509_3444} {RNA1310_89} {RNA815_1814}
11. MligTC455_48022 1337 27.86 Mlig455_045267, Mlig455_069186

Neo: -

Age: -

Region-enriched R2: 2.130/0.00146

4.323 - 0.745 0.880 0.742 0.966 0.990

Mlig455_045267 {REF} {Length: 3628} {Pfam: Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeats (many copies) [PF13637.8, score=28.4]; Ankyrin repeats (3 copies) [PF12796.9, score=28.3]; Ankyrin repeat [PF13606.8, score=23.5]} {Celegans: WBGene00009375, F34D10.6, [Score=57.0, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_3, dd_Smed_v6_5594_0_3, [Score=58.5, Expect=1e-08]} {RNA1509_17412, RNA1509_32079} {RNA1310_5952, RNA1509_17412, RNA1509_32079} {RNA1509_17412, RNA1509_32079, RNA815_2323}

Mlig455_069186 {REF} {Length: 3598} {Pfam: Ankyrin repeats (many copies) [PF13637.8, score=30.4]; Ankyrin repeats (3 copies) [PF12796.9, score=30.1]; Ankyrin repeats (many copies) [PF13857.8, score=29.5]; Ankyrin repeat [PF13606.8, score=24.1]} {Celegans: WBGene00009375, F34D10.6, [Score=56.6, Expect=6e-08]} {Smed: dd_Smed_v6_5594_0_4, dd_Smed_v6_5594_0_4, [Score=59.3, Expect=7e-09]} {RNA1509_52963} {RNA1310_5952, RNA1509_52963} {RNA1509_52963, RNA815_2323}
12. MligTC455_47190 3794 79.04 Mlig455_044419, Mlig455_044420, Mlig455_044455

Neo: -

Age: -

Region-enriched R8: 3.373/0.00004
Region-enriched R7: 2.224/0.04308

4.293 0.859 0.816 0.801 - 0.970 0.847

Mlig455_044419 {REF} {Length: 1036} {RNA1509_30179} {RNA1310_60147} {RNA815_30734}

Mlig455_044420 {REF} {Length: 1088} {RNA1509_30179} {RNA1310_60147} {RNA815_30734}

Mlig455_044455 {REF} {Length: 1883} {Smed: dd_Smed_v6_1588_0_1, dd_Smed_v6_1588_0_1, [Score=41.2, Expect=6e-06]} {RNA1509_30179} {RNA1310_60147, RNA1509_30179} {RNA1509_30179, RNA815_30734}
13. MligTC455_31164 572 11.91 Mlig455_029609, Mlig455_045673

Neo: -

Age: -

4.235 - 0.754 0.880 0.722 0.972 0.907

Mlig455_029609 {REF} {Length: 746} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=39.4]} {Smed: dd_Smed_v6_22533_0_1, dd_Smed_v6_22533_0_1, [Score=48.5, Expect=1e-06]} {RNA1310_96354} {RNA815_44390}

Mlig455_045673 {REF} {Length: 2025} {RNA1509_21720} {RNA1310_14760} {RNA815_24583}
14. MligTC455_42376 61 1.27 Mlig455_069890

Neo: -

Age: -

4.224 - 0.751 0.864 0.781 0.953 0.875 Mlig455_069890 {REF} {Length: 630} {TRANSSPLICED} {Pfam: PAN domain [PF00024.28, score=26.1]} {RNA1509_53783} {RNA1310_37190} {RNA815_24434}
15. MligTC455_34369 112 2.34 Mlig455_015308, Mlig455_015354, Mlig455_036248, Mlig455_068737, Mlig455_070110

Neo: -

Age: Up-Down-Up

Region-enriched R2: 5.462/0.00546

4.22 - 0.753 0.892 0.743 0.961 0.871

Mlig455_015308 {REF} {Length: 1459} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=63.9]} {RNA1310_34740} {RNA815_15663}

Mlig455_015354 {REF} {Length: 1446} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=66.3]; Sialidase, N-terminal domain [PF02973.18, score=18.5]} {RNA1310_34740} {RNA815_15663}

Mlig455_036248 {REF} {Length: 2111} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=120.9]; Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=28.5]; PAN domain [PF00024.28, score=19.9]} {RNA1509_45496} {RNA1310_2539.1} {RNA815_252.1}

Mlig455_068737 {REF} {Length: 1096} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=68.3]; Sialidase, N-terminal domain [PF02973.18, score=19.9]} {RNA1310_34740} {RNA815_37905}

Mlig455_070110 {REF} {Length: 1340} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=109.6]} {RNA1509_32599} {RNA1310_1659} {RNA815_252.1}
16. MligTC455_38682 102 2.12 Mlig455_039641

Neo: -

Age: -

Region-enriched R2: 6.138/0.02363

SLC18A3 4.215 - 0.720 0.871 0.780 0.958 0.886 Mlig455_039641 {REF} {Length: 3925} {Pfam: Major Facilitator Superfamily [PF07690.18, score=147.1]; Sugar (and other) transporter [PF00083.26, score=29.0]; LacY proton/sugar symporter [PF01306.21, score=20.2]} {Human: ENSG00000187714, SLC18A3, solute carrier family 18 member A3, [RH, Score=469, Expect=9e-161]} {Mouse: ENSMUSG00000100241, Slc18a3, solute carrier family 18 (vesicular monoamine), member 3, [RH, Score=469, Expect=1e-160]} {Dmel: FBgn0270928, VAChT, Vesicular acetylcholine transporter, [RH, Score=513, Expect=2e-177]} {Celegans: WBGene00006756, unc-17, Vesicular acetylcholine transporter unc-17, [RH, Score=486, Expect=2e-167]} {Smed: dd_Smed_v6_11630_0_1, dd_Smed_v6_11630_0_1, [RH, Score=563, Expect=0.0]} {RNA1310_28397} {RNA815_32284.1}
17. MligTC455_47080 362 7.54 Mlig455_037356

Neo: -

Age: -

Region-enriched R2: 2.691/0.00566

SSUH2 4.192 - 0.801 0.782 0.741 0.957 0.911 Mlig455_037356 {REF} {Length: 1984} {Pfam: DnaJ central domain [PF00684.21, score=20.9]} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=189, Expect=3e-56]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=156, Expect=5e-44]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=90.9, Expect=7e-20]} {RNA1509_29510} {RNA1310_15488, RNA1509_29510} {RNA1509_29510, RNA815_5650}
18. MligTC455_19276 1694 35.28 Mlig455_057303

Neo: -

Age: Down-Down-Up

Region-specific R2: 5.711

Region-enriched R2: 6.117/0.00000
Region-enriched R3: 2.663/0.00058

4.171 - 0.751 0.756 0.796 0.969 0.899 Mlig455_057303 {REF} {Length: 1196} {Pfam: TATA-binding related factor (TRF) of subunit 20 of Mediator complex [PF08612.13, score=80.6]} {Smed: dd_Smed_v6_9879_0_1, dd_Smed_v6_9879_0_1, [RH, Score=73.9, Expect=1e-15]} {RNA1509_58478} {RNA1310_35292} {RNA815_20171}
19. MligTC455_51710 3251 67.72 Mlig455_024427

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.451

Region-enriched R8: 1.126/0.01211

4.134 - 0.910 0.745 0.719 0.990 0.770 Mlig455_024427 {REF} {Length: 2323} {RNA1509_28514} {RNA1310_24129} {RNA815_10418.2}
20. MligTC455_19278 4335 90.31 Mlig455_057304, Mlig455_070944

Neo: -

Age: logFC(26M/2M)=0.686

Region-specific R2: 5.590

Region-enriched R2: 5.465/0.00000
Region-enriched R3: 2.308/0.00629

CHRNA10 4.119 - 0.755 0.719 0.780 0.968 0.897

Mlig455_057304 {REF} {Length: 1001} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=71.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=77.0, Expect=2e-16]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=75.9, Expect=4e-16]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=75.5, Expect=6e-16]; ENSMUSG00000031491, Chrna6, cholinergic receptor, nicotinic, alpha polypeptide 6, [Score=73.9, Expect=2e-15]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=93.6, Expect=2e-22]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=100, Expect=5e-25]} {Smed: dd_Smed_v6_11955_0_1, dd_Smed_v6_11955_0_1, [Score=82.8, Expect=8e-19]} {RNA1509_23115} {RNA1310_34970} {RNA815_15305.1}

Mlig455_070944 {REF} {Length: 1060} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=88.2]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=95.9, Expect=6e-22]} {Mouse: ENSMUSG00000066279, Chrna10, cholinergic receptor, nicotinic, alpha polypeptide 10, [Score=96.3, Expect=3e-22]; ENSMUSG00000022041, Chrna2, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal), [Score=94.7, Expect=1e-21]} {Dmel: FBgn0086778, nAChRalpha7, nicotinic Acetylcholine Receptor alpha7, [Score=112, Expect=7e-28]} {Celegans: WBGene00000058, acr-19, AcetylCholine Receptor; Acetylcholine receptor (63.2 kD) (Acr-19), [Score=118, Expect=4e-30]} {Smed: dd_Smed_v6_18184_0_1, dd_Smed_v6_18184_0_1, [Score=98.6, Expect=2e-23]} {RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1310_34970, RNA1509_23115, RNA1509_43907, RNA1509_9432} {RNA1509_23115, RNA1509_43907, RNA1509_9432, RNA815_15305.1}
21. MligTC455_42840 147 3.06 Mlig455_003645

Neo: -

Age: -

4.103 - 0.742 0.848 0.773 0.959 0.781 Mlig455_003645 {REF} {Length: 1270} {RNA1509_48973} {RNA1310_36721} {RNA815_36286}
22. MligTC455_46667 769 16.02 Mlig455_007827

Neo: -

Age: -

Region-enriched R2: 2.396/0.00004

PLSCR3 4.077 - 0.737 0.716 0.857 0.985 0.782 Mlig455_007827 {REF} {Length: 946} {Pfam: Scramblase [PF03803.17, score=174.8]} {Human: ENSG00000187838, PLSCR3, phospholipid scramblase 3, [Score=155, Expect=1e-46]; ENSG00000284009, PLSCR3, phospholipid scramblase 3, [Score=155, Expect=1e-46]; ENSG00000188313, PLSCR1, phospholipid scramblase 1, [Score=153, Expect=2e-46]} {Mouse: ENSMUSG00000032369, Plscr1, phospholipid scramblase 1, [Score=162, Expect=4e-49]; ENSMUSG00000019461, Plscr3, phospholipid scramblase 3, [Score=158, Expect=9e-48]} {Dmel: FBgn0052056, scramb1, scramblase 1, [Score=151, Expect=7e-46]} {Celegans: WBGene00014200, scrm-2, Phospholipid scramblase, [Score=124, Expect=4e-35]} {Smed: dd_Smed_v6_16813_0_1, dd_Smed_v6_16813_0_1, [Score=206, Expect=3e-66]} {RNA1509_32731, RNA1509_35060, RNA1509_60038} {RNA1310_24943, RNA1509_32731, RNA1509_35060, RNA1509_60038} {RNA1509_32731, RNA1509_35060, RNA1509_60038, RNA815_10647}
23. MligTC455_34115 6573 136.93 Mlig455_017846, Mlig455_047865

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.581

Region-enriched R2: 4.896/0.00130

4.072 - 0.715 0.768 0.759 0.965 0.865

Mlig455_017846 {REF} {Length: 1260} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1310_63880, RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701} {RNA1509_3560, RNA1509_36840, RNA1509_42552, RNA1509_4845, RNA1509_7701, RNA815_12890.1}

Mlig455_047865 {REF} {Length: 1135} {RNA1509_4845} {RNA1310_63880} {RNA815_12890.1}
24. MligTC455_53579 15576 324.49 Mlig455_010515

Neo: -

Age: -

Region-enriched R2: 1.446/0.00265

Regeneration-downregulated BL: -1.566

Regeneration-depleted BL: -1.566

4.061 - 0.846 0.729 0.759 0.951 0.776 Mlig455_010515 {REF} {Length: 1448} {Pfam: Neuroendocrine protein 7B2 precursor (Secretogranin V) [PF05281.13, score=80.3]} {Dmel: FBgn0041707, 7B2, [RH, Score=70.1, Expect=2e-13]} {Celegans: WBGene00011392, sbt-1, Seven B Two (Mammalian 7BT prohormone convertase chaperone) homolog, [RH, Score=67.4, Expect=5e-13]} {Smed: dd_Smed_v6_3862_0_1, dd_Smed_v6_3862_0_1, [RH, Score=119, Expect=7e-32]} {RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1310_24594, RNA1509_1202, RNA1509_1348, RNA1509_17830} {RNA1509_1202, RNA1509_1348, RNA1509_17830, RNA815_8289}
25. MligTC455_44050 2086 43.46 Mlig455_028045, Mlig455_028051

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.242

Region-specific R2: 6.161

Region-enriched R2: 7.072/0.00000
Region-enriched R3: 3.149/0.00025

3.974 - 0.767 0.743 0.795 0.960 0.709

Mlig455_028045 {REF} {Length: 1156} {RNA1509_31459, RNA1509_3903} {RNA1310_2730.2, RNA1509_31459, RNA1509_3903} {RNA1509_31459, RNA1509_3903, RNA815_7682}

Mlig455_028051 {REF} {Length: 871} {NoTransDecoderORF} {RNA1509_3903} {RNA1310_15260} {RNA815_7682}
26. MligTC455_27692 1230 25.62 Mlig455_041598

Neo: -

Age: logFC(26M/2M)=-0.459

Region-enriched R7: 1.679/0.00325
Region-enriched R8: 1.607/0.03580
Region-enriched R2: 1.508/0.02284

TUBA1A 3.741 - 0.922 0.918 - 0.973 0.928 Mlig455_041598 {REF} {Length: 2325} {Pfam: Tubulin/FtsZ family, GTPase domain [PF00091.27, score=229.7]; Tubulin C-terminal domain [PF03953.19, score=175.5]; Tubulin domain [PF14881.8, score=18.9]} {Human: ENSG00000167552, TUBA1A, tubulin alpha 1a, [RH, Score=926, Expect=0.0]; ENSG00000123416, TUBA1B, tubulin alpha 1b, [RH, Score=923, Expect=0.0]; ENSG00000167553, TUBA1C, tubulin alpha 1c, [RH, Score=887, Expect=0.0]} {Mouse: ENSMUSG00000072235, Tuba1a, tubulin, alpha 1A, [RH, Score=926, Expect=0.0]; ENSMUSG00000023004, Tuba1b, tubulin, alpha 1B, [RH, Score=923, Expect=0.0]} {Dmel: FBgn0003884, alphaTub84B, alpha-Tubulin at 84B, [RH, Score=917, Expect=0.0]} {Celegans: WBGene00003175, mec-12, Tubulin alpha-3 chain Detyrosinated tubulin alpha-3 chain, [RH, Score=850, Expect=0.0]} {Smed: dd_Smed_v6_38_0_1, dd_Smed_v6_38_0_1, [RH, Score=924, Expect=0.0]} {RNA1509_21352, RNA1509_42319, RNA1509_9718} {RNA1310_10339.1, RNA1509_21352, RNA1509_42319} {RNA1509_21352, RNA1509_42319, RNA815_1715.1}
27. MligTC455_19030 628 13.08 Mlig455_046052

Neo: -

Age: -

Region-enriched R2: 3.353/0.00000

ADGRL3 3.664 - - 0.804 0.993 0.971 0.896 Mlig455_046052 {REF} {Length: 7405} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=104.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=61.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=54.3]; GPCR-Autoproteolysis INducing (GAIN) domain [PF16489.7, score=28.0]} {Human: ENSG00000150471, ADGRL3, adhesion G protein-coupled receptor L3, [Score=157, Expect=8e-38]} {Mouse: ENSMUSG00000037605, Adgrl3, adhesion G protein-coupled receptor L3, [Score=158, Expect=5e-38]} {Dmel: FBgn0033313, Cirl, Calcium-independent receptor for alpha-latrotoxin, [RH, Score=72.4, Expect=5e-12]} {Celegans: WBGene00002251, lat-1, Latrophilin-like protein 1, [Score=107, Expect=5e-23]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=587, Expect=1e-173]} {RNA1509_17130, RNA1509_4023, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1310_254.2, RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867} {RNA1509_17130, RNA1509_47993, RNA1509_50945, RNA1509_52292, RNA1509_52867, RNA815_85.1}
28. MligTC455_35258 2779 57.89 Mlig455_040964

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.469

Region-enriched R2: 1.501/0.00133

3.545 - - 0.876 0.785 0.983 0.901 Mlig455_040964 {REF} {Length: 8259} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [Score=543, Expect=9e-160]} {RNA1509_16633, RNA1509_52679} {RNA1310_236.2, RNA1509_16633} {RNA1509_16633, RNA815_77.1}
29. MligTC455_46394 8810 183.54 Mlig455_054818, Mlig455_054826

Neo: -

Age: -

Region-specific R2: 1.771

Region-enriched R2: 1.255/0.00038

PKD2 3.521 - - 0.857 0.806 0.975 0.883

Mlig455_054818 {REF} {Length: 2992} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=750, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=747, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=380, Expect=6e-120]} {Smed: dd_Smed_v6_17348_0_3, dd_Smed_v6_17348_0_3, [Score=733, Expect=0.0]} {RNA1509_1615} {RNA1310_21296.2, RNA1509_1615} {RNA1509_1615, RNA815_3158.1}

Mlig455_054826 {REF} {Length: 3118} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.7]; Ion transport protein [PF00520.33, score=93.4]; EF hand [PF00036.34, score=32.6]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.2]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=754, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=751, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=2e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=1e-122]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
30. MligTC455_48651 1312 27.33 Mlig455_038678

Neo: -

Age: -

Region-specific R2: 3.201

Region-enriched R2: 2.599/0.00005

PTPRN 3.512 - 0.803 - 0.939 0.960 0.810 Mlig455_038678 {REF} {Length: 3539} {Pfam: Protein-tyrosine phosphatase [PF00102.29, score=232.2]} {Human: ENSG00000054356, PTPRN, protein tyrosine phosphatase, receptor type N, [RH, Score=424, Expect=2e-134]; ENSG00000155093, PTPRN2, protein tyrosine phosphatase, receptor type N2, [RH, Score=417, Expect=1e-130]} {Mouse: ENSMUSG00000026204, Ptprn, protein tyrosine phosphatase, receptor type, N, [RH, Score=428, Expect=3e-135]; ENSMUSG00000056553, Ptprn2, protein tyrosine phosphatase, receptor type, N polypeptide 2, [RH, Score=413, Expect=3e-129]} {Dmel: FBgn0031294, IA-2, IA-2 protein tyrosine phosphatase, [RH, Score=390, Expect=2e-118]} {Celegans: WBGene00002048, ida-1, IA2; IDA-1 protein; Related to Islet cell Diabetes Autoantigen, [Score=287, Expect=8e-85]} {Smed: dd_Smed_v6_6990_0_1, dd_Smed_v6_6990_0_1, [RH, Score=397, Expect=2e-126]} {RNA1509_1051, RNA1509_26823, RNA1509_32982, RNA1509_35716} {RNA1310_3791, RNA1509_1051, RNA1509_26823, RNA1509_32982, RNA1509_35716} {RNA1509_1051, RNA1509_26823, RNA1509_32982, RNA1509_35716, RNA815_1009}
31. MligTC455_46395 870 18.13 Mlig455_069471

Neo: -

Age: logFC(26M/2M)=0.458

PKD2 3.494 - - 0.876 0.705 0.972 0.941 Mlig455_069471 {REF} {Length: 3122} {TRANSSPLICED} {Pfam: Polycystin cation channel [PF08016.14, score=487.8]; Ion transport protein [PF00520.33, score=93.3]; EF hand [PF00036.34, score=32.7]; Ferredoxin I 4Fe-4S cluster domain [PF18109.3, score=21.3]} {Human: ENSG00000118762, PKD2, polycystin 2, transient receptor potential cation channel, [RH, Score=753, Expect=0.0]} {Mouse: ENSMUSG00000034462, Pkd2, polycystic kidney disease 2, [RH, Score=750, Expect=0.0]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=323, Expect=1e-96]} {Celegans: WBGene00004035, pkd-2, Polycystin-2, [Score=387, Expect=8e-123]} {Smed: dd_Smed_v6_13327_0_1, dd_Smed_v6_13327_0_1, [RH, Score=769, Expect=0.0]} {RNA1509_13522} {RNA1310_21296.2} {RNA815_3158.1}
32. MligTC455_14716 29 0.61 Mlig455_043633

Neo: -

Age: -

ANGPTL2 3.479 - 0.709 0.892 - 0.973 0.905 Mlig455_043633 {REF} {Length: 1106} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=157.6]} {Human: ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=134, Expect=2e-35]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=133, Expect=4e-35]; ENSG00000085265, FCN1, ficolin 1, [Score=132, Expect=8e-36]; ENSG00000160339, FCN2, ficolin 2, [Score=128, Expect=4e-35]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=137, Expect=1e-36]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=131, Expect=1e-34]} {Dmel: FBgn0034160, CG5550, [Score=119, Expect=6e-32]} {Celegans: WBGene00017013, ensh-1, [Score=57.8, Expect=2e-09]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=114, Expect=1e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
33. MligTC455_24753 11 0.23 Mlig455_016700

Neo: -

Age: -

3.478 - - 0.873 0.768 0.974 0.863 Mlig455_016700 {REF} {Length: 1032} {Pfam: PAN domain [PF00024.28, score=20.1]} {RNA1310_36328.1} {RNA815_39270}
34. MligTC455_34524 155 3.22 Mlig455_021291

Neo: -

Age: Down-Up-Down

Region-specific R2: 4.905

Region-enriched R2: 4.200/0.01842

3.474 - 0.771 0.839 - 0.951 0.913 Mlig455_021291 {REF} {Length: 1478} {NoTransDecoderORF} {RNA1509_56543} {RNA1310_26920, RNA1509_56543} {RNA1509_56543, RNA815_11718}
35. MligTC455_14715 31 0.65 Mlig455_043609

Neo: -

Age: -

ANGPTL1 3.464 - 0.709 0.884 - 0.966 0.905 Mlig455_043609 {REF} {Length: 1252} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=154.2]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=131, Expect=2e-34]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=128, Expect=2e-33]; ENSG00000085265, FCN1, ficolin 1, [Score=128, Expect=2e-34]; ENSG00000160339, FCN2, ficolin 2, [Score=125, Expect=5e-34]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=134, Expect=1e-35]; ENSMUSG00000038742, Angptl6, angiopoietin-like 6, [Score=129, Expect=7e-34]; ENSMUSG00000004105, Angptl2, angiopoietin-like 2, [Score=128, Expect=2e-33]} {Dmel: FBgn0033312, CG8642, [RH, Score=122, Expect=1e-31]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=112, Expect=7e-28]} {RNA1509_26827} {RNA1310_31596.2} {RNA815_17173.3}
36. MligTC455_17464 409 8.52 Mlig455_048989, Mlig455_049006, Mlig455_067762

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.512

Regeneration-downregulated BL: -7.800

Regeneration-depleted BL: -7.800

3.458 - 0.711 0.877 - 0.952 0.918

Mlig455_048989 {REF} {Length: 1272} {RNA1310_37715} {RNA815_39767}

Mlig455_049006 {REF} {Length: 1028} {RNA1310_37715} {RNA815_39767}

Mlig455_067762 {REF} {Length: 1353} {RNA1310_37715} {RNA815_39767}
37. MligTC455_19908 490 10.21 Mlig455_047266, Mlig455_047318, Mlig455_069346

Neo: -

Age: logFC(26M/2M)=0.566

3.457 - - 0.858 0.728 0.977 0.894

Mlig455_047266 {REF} {Length: 1728} {Pfam: Glycine rich protein [PF12810.9, score=49.4]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}

Mlig455_047318 {REF} {Length: 2268} {Pfam: Glycine rich protein [PF12810.9, score=36.7]} {RNA1509_28009} {RNA1310_17226, RNA1509_28009} {RNA1509_28009, RNA815_32720}

Mlig455_069346 {REF} {Length: 1953} {Pfam: Glycine rich protein [PF12810.9, score=31.6]} {RNA1509_28009} {RNA1310_17226} {RNA815_32720}
38. MligTC455_52128 26 0.54 Mlig455_056382

Neo: -

Age: -

3.449 - - 0.823 0.746 0.980 0.900 Mlig455_056382 {REF} {Length: 892} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=20.5]; Ankyrin repeat [PF00023.32, score=19.7]} {RNA1310_149618}
39. MligTC455_25589 1419 29.55 Mlig455_029945

Neo: -

Age: -

Region-enriched R2: 2.293/0.00000

Regeneration-downregulated BL: -3.516

Regeneration-depleted BL: -3.516

3.441 - 0.832 0.826 0.794 0.989 - Mlig455_029945 {REF} {Length: 1261} {Pfam: Helix-turn-helix domain [PF12645.9, score=19.8]; Domain of unknown function (DUF1848) [PF08902.13, score=19.3]} {RNA1509_17753} {RNA1310_70608, RNA1509_17753} {RNA1509_17753, RNA815_1498.1}
40. MligTC455_16415 197 4.1 Mlig455_000401

Neo: -

Age: -

Region-enriched R2: 4.276/0.00982

ROR1 3.434 - - 0.800 0.738 0.992 0.904 Mlig455_000401 {REF} {Length: 3780} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=233.3]; Protein kinase domain [PF00069.27, score=85.9]; Immunoglobulin I-set domain [PF07679.18, score=49.4]; Immunoglobulin domain [PF13927.8, score=46.6]; Immunoglobulin domain [PF00047.27, score=31.9]; Immunoglobulin domain [PF13895.8, score=30.0]; Fz domain [PF01392.24, score=27.6]; Kringle domain [PF00051.20, score=22.3]; Immunoglobulin V-set domain [PF07686.19, score=19.5]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [RH, Score=390, Expect=1e-119]; ENSG00000169071, ROR2, receptor tyrosine kinase like orphan receptor 2, [RH, Score=379, Expect=1e-115]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [RH, Score=386, Expect=1e-118]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [RH, Score=377, Expect=4e-115]} {Dmel: FBgn0010407, Ror, [Score=286, Expect=3e-84]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=285, Expect=4e-82]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [RH, Score=439, Expect=2e-139]} {RNA1509_35395} {RNA1310_13558, RNA1509_35395} {RNA1509_35395, RNA815_27446}
41. MligTC455_53843 1448 30.17 Mlig455_048664

Neo: -

Age: logFC(26M/2M)=0.488

3.425 - 0.743 0.865 - 0.966 0.851 Mlig455_048664 {REF} {Length: 1660} {RNA1509_15580} {RNA1310_24090, RNA1509_15580} {RNA1509_15580, RNA815_10676.2}
42. MligTC455_38368 107 2.24 Mlig455_026435, Mlig455_044757

Neo: -

Age: Up-Down-Down

SSUH2 3.418 - 0.716 0.818 - 0.990 0.894

Mlig455_026435 {REF} {Length: 1789} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [RH, Score=233, Expect=1e-72]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [RH, Score=195, Expect=1e-58]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=117, Expect=3e-29]} {RNA1509_6425} {RNA1310_32434} {RNA815_16161}

Mlig455_044757 {REF} {Length: 883} {TRANSSPLICED} {RNA1509_28356} {RNA1310_61125} {RNA815_53103}
43. MligTC455_27025 706 14.7 Mlig455_054786, Mlig455_054878

Neo: -

Age: -

Region-enriched R2: 3.519/0.00005

CD82 3.414 - - 0.881 0.713 0.970 0.850

Mlig455_054786 {REF} {Length: 2796} {Pfam: Tetraspanin family [PF00335.22, score=142.8]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=86.3, Expect=4e-19]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=94.0, Expect=3e-22]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=98.6, Expect=6e-24]} {Celegans: WBGene00006632, tsp-6, Tetraspanin, [Score=74.7, Expect=1e-15]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1310_8032.1, RNA1509_20389, RNA1509_43644, RNA1509_56428} {RNA1509_20389, RNA1509_43644, RNA1509_56428, RNA815_3380.1}

Mlig455_054878 {REF} {Length: 4398} {Pfam: Tetraspanin family [PF00335.22, score=143.7]} {Human: ENSG00000085117, CD82, CD82 molecule, [RH, Score=84.7, Expect=2e-18]} {Mouse: ENSMUSG00000027215, Cd82, CD82 antigen, [RH, Score=92.4, Expect=2e-21]} {Dmel: FBgn0035936, Tsp66E, Tetraspanin 66E, [Score=99.8, Expect=4e-24]} {Celegans: WBGene00006643, tsp-17, TetraSPanin family, [RH, Score=73.2, Expect=1e-14]} {Smed: dd_Smed_v6_13639_0_1, dd_Smed_v6_13639_0_1, [RH, Score=160, Expect=2e-47]} {RNA1509_56428} {RNA1310_8032.2} {RNA815_3380.1}
44. MligTC455_39481 461 9.6 Mlig455_056703, Mlig455_060318

Neo: -

Age: Down-Up-Up

Region-specific R2: 4.222

ANGPTL1 3.411 - - 0.795 0.760 0.956 0.900

Mlig455_056703 {REF} {Length: 1114} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=79.0]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=89.4, Expect=1e-19]; ENSG00000136859, ANGPTL2, angiopoietin like 2, [Score=85.1, Expect=3e-18]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=91.3, Expect=2e-20]} {Dmel: FBgn0033312, CG8642, [Score=82.4, Expect=1e-17]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=76.3, Expect=1e-15]} {RNA1310_31288} {RNA815_20497.1}

Mlig455_060318 {REF} {Length: 1175} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=112.7]} {Human: ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=106, Expect=2e-25]; ENSG00000171819, ANGPTL7, angiopoietin like 7, [Score=105, Expect=6e-26]} {Mouse: ENSMUSG00000033544, Angptl1, angiopoietin-like 1, [Score=109, Expect=1e-26]} {Dmel: FBgn0034160, CG5550, [Score=96.3, Expect=2e-23]} {Celegans: WBGene00016769, C49C8.5, [Score=47.0, Expect=9e-06]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=88.2, Expect=2e-19]} {RNA1310_31288} {RNA815_20497.1}
45. MligTC455_29049 441 9.18 Mlig455_042244

Neo: -

Age: -

Region-enriched R2: 4.677/0.00000
Region-enriched R3: 2.595/0.01002

RASGRF1 3.408 - - 0.756 0.900 0.964 0.788 Mlig455_042244 {REF} {Length: 6465} {Pfam: RasGEF domain [PF00617.21, score=193.2]; RhoGEF domain [PF00621.22, score=119.3]; PH domain [PF00169.31, score=86.7]; RasGEF N-terminal motif [PF00618.22, score=68.4]; Pleckstrin homology domain [PF15413.8, score=22.6]} {Human: ENSG00000058335, RASGRF1, Ras protein specific guanine nucleotide releasing factor 1, [RH, Score=763, Expect=0.0]; ENSG00000113319, RASGRF2, Ras protein specific guanine nucleotide releasing factor 2, [RH, Score=739, Expect=0.0]} {Mouse: ENSMUSG00000032356, Rasgrf1, RAS protein-specific guanine nucleotide-releasing factor 1, [RH, Score=763, Expect=0.0]} {Dmel: FBgn0001965, Sos, Son of sevenless, [Score=164, Expect=3e-40]} {Celegans: WBGene00004947, sos-1, Son of sevenless homolog, [Score=118, Expect=3e-26]} {Smed: dd_Smed_v6_18313_0_2, dd_Smed_v6_18313_0_2, [RH, Score=1137, Expect=0.0]} {RNA1509_15697} {RNA1310_2543.1} {RNA815_8228.1}
46. MligTC455_50349 31 0.65 Mlig455_043966

Neo: -

Age: -

3.398 - - 0.829 0.750 0.954 0.865 Mlig455_043966 {REF} {Length: 615} {NoTransDecoderORF} {RNA1509_42587} {RNA1310_27550.1} {RNA815_55700}
47. MligTC455_03841 920 19.16 Mlig455_018790, Mlig455_048140

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.474

Region-enriched R2: 5.915/0.00081

NKX2-1, NKX2-4 3.386 - 0.793 - 0.775 0.994 0.824

Mlig455_018790 {REF} {Length: 2203} {Pfam: Homeodomain [PF00046.31, score=72.7]} {Human: ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]; ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=2e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=145, Expect=2e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=8e-47]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=134, Expect=2e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=191, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401} {RNA815_21584}

Mlig455_048140 {REF} {Length: 2218} {Pfam: Homeodomain [PF00046.31, score=72.5]} {Human: ENSG00000125816, NKX2-4, NK2 homeobox 4, [RH, Score=145, Expect=3e-39]; ENSG00000136352, NKX2-1, NK2 homeobox 1, [RH, Score=145, Expect=7e-39]} {Mouse: ENSMUSG00000001496, Nkx2-1, NK2 homeobox 1, [RH, Score=144, Expect=6e-39]} {Dmel: FBgn0028993, scro, scarecrow, [RH, Score=166, Expect=2e-46]} {Celegans: WBGene00000447, ceh-24, Homeobox protein ceh-24, [RH, Score=136, Expect=1e-36]} {Smed: dd_Smed_v6_6729_0_1, dd_Smed_v6_6729_0_1, [RH, Score=193, Expect=1e-57]} {RNA1509_12761} {RNA1310_13401, RNA1509_12761} {RNA1509_12761, RNA815_21584}
48. MligTC455_32359 194 4.04 Mlig455_054395, Mlig455_054418, Mlig455_070496

Neo: -

Age: -

Region-enriched R2: 3.120/0.02401

STON2 3.372 - 0.728 0.833 - 0.965 0.846

Mlig455_054395 {REF} {Length: 3807} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=152.1]} {Human: ENSG00000140022, STON2, stonin 2, [RH, Score=281, Expect=5e-80]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [RH, Score=285, Expect=3e-82]} {Dmel: FBgn0016975, stnB, stoned B, [RH, Score=374, Expect=3e-112]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [RH, Score=356, Expect=3e-104]} {Smed: dd_Smed_v6_6859_0_1, dd_Smed_v6_6859_0_1, [RH, Score=684, Expect=0.0]} {RNA1509_39423} {RNA1310_6760} {RNA815_11749}

Mlig455_054418 {REF} {Length: 3915} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=153.1]} {Human: ENSG00000140022, STON2, stonin 2, [RH, Score=281, Expect=3e-80]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [RH, Score=284, Expect=5e-82]} {Dmel: FBgn0016975, stnB, stoned B, [RH, Score=374, Expect=4e-112]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [RH, Score=355, Expect=4e-104]} {Smed: dd_Smed_v6_6859_0_1, dd_Smed_v6_6859_0_1, [RH, Score=686, Expect=0.0]} {RNA1509_39423} {RNA1310_6760, RNA1509_39423} {RNA1509_39423, RNA815_11749}

Mlig455_070496 {REF} {Length: 3566} {Pfam: Adaptor complexes medium subunit family [PF00928.23, score=76.5]} {Human: ENSG00000140022, STON2, stonin 2, [Score=178, Expect=9e-46]} {Mouse: ENSMUSG00000020961, Ston2, stonin 2, [Score=182, Expect=2e-47]} {Dmel: FBgn0016975, stnB, stoned B, [Score=250, Expect=7e-70]} {Celegans: WBGene00006777, unc-41, Putative stoned B-like protein, [Score=235, Expect=1e-64]} {Smed: dd_Smed_v6_6859_0_2, dd_Smed_v6_6859_0_2, [Score=467, Expect=5e-152]} {RNA1509_39423} {RNA1310_6760} {RNA815_11749}
49. MligTC455_53844 1403 29.24 Mlig455_051626

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.540

3.34 - 0.744 0.772 - 0.974 0.850 Mlig455_051626 {REF} {Length: 1671} {RNA1509_15580} {RNA1310_24090} {RNA815_10676.2}
50. MligTC455_25588 1046 21.8 Mlig455_029794

Neo: -

Age: -

Region-enriched R2: 2.896/0.00002

3.316 - 0.812 - 0.807 0.994 0.703 Mlig455_029794 {REF} {Length: 1354} {Pfam: Domain of unknown function (DUF4573) [PF15140.8, score=40.1]; Domain of unknown function (DUF1848) [PF08902.13, score=20.8]} {RNA1509_17753} {RNA1310_70608} {RNA815_1498.1}
51. MligTC455_53190 105 2.18 Mlig455_013516

Neo: -

Age: -

SCNN1B 3.31 - - 0.723 0.744 0.957 0.886 Mlig455_013516 {REF} {Length: 2819} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=290.8]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=158, Expect=8e-41]} {Mouse: ENSMUSG00000000216, Scnn1g, sodium channel, nonvoltage-gated 1 gamma, [Score=149, Expect=1e-37]} {Dmel: FBgn0051105, ppk22, pickpocket 22, [RH, Score=60.1, Expect=3e-09]} {Celegans: WBGene00006748, unc-8, Degenerin unc-8, [RH, Score=166, Expect=2e-43]} {Smed: dd_Smed_v6_17021_0_1, dd_Smed_v6_17021_0_1, [RH, Score=186, Expect=1e-51]} {RNA1509_18670} {RNA1310_20526} {RNA815_9932}
52. MligTC455_16416 290 6.04 Mlig455_000468

Neo: -

Age: -

Region-enriched R2: 2.225/0.04782

ROR1 3.294 - - 0.726 0.702 0.992 0.874 Mlig455_000468 {REF} {Length: 2686} {Pfam: Protein tyrosine and serine/threonine kinase [PF07714.19, score=208.1]; Protein kinase domain [PF00069.27, score=77.3]; Kringle domain [PF00051.20, score=19.4]} {Human: ENSG00000185483, ROR1, receptor tyrosine kinase like orphan receptor 1, [Score=300, Expect=1e-89]} {Mouse: ENSMUSG00000035305, Ror1, receptor tyrosine kinase-like orphan receptor 1, [Score=295, Expect=2e-87]; ENSMUSG00000021464, Ror2, receptor tyrosine kinase-like orphan receptor 2, [Score=281, Expect=2e-82]} {Dmel: FBgn0010407, Ror, [Score=259, Expect=2e-76]} {Celegans: WBGene00000289, cam-1, Tyrosine-protein kinase receptor cam-1, [Score=217, Expect=2e-60]} {Smed: dd_Smed_v6_7911_0_1, dd_Smed_v6_7911_0_1, [Score=328, Expect=1e-100]} {RNA1509_35395} {RNA1310_13558} {RNA815_27446}
53. MligTC455_49307 122 2.55 Mlig455_055230

Neo: -

Age: -

Region-enriched R2: 4.447/0.04819

ZAN 3.268 - - 0.729 0.744 0.981 0.814 Mlig455_055230 {REF} {Length: 2947} {Pfam: Glycine rich protein [PF12810.9, score=28.6]} {Human: ENSG00000146839, ZAN, zonadhesin (gene/pseudogene), [Score=79.7, Expect=1e-14]} {Mouse: ENSMUSG00000079173, Zan, zonadhesin, [Score=80.1, Expect=7e-15]} {RNA1310_18897} {RNA815_40026}
54. MligTC455_38657 292 6.08 Mlig455_021581

Neo: -

Age: -

CPLX1 3.257 - 0.746 0.805 - 0.968 0.738 Mlig455_021581 {REF} {Length: 2085} {Pfam: Synaphin protein [PF05835.14, score=132.9]} {Human: ENSG00000168993, CPLX1, complexin 1, [Score=52.4, Expect=8e-09]; ENSG00000145920, CPLX2, complexin 2, [Score=50.8, Expect=1e-08]} {Mouse: ENSMUSG00000033615, Cplx1, complexin 1, [Score=53.5, Expect=2e-09]} {Dmel: FBgn0041605, cpx, complexin, [RH, Score=90.1, Expect=1e-23]} {Celegans: WBGene00022271, cpx-1, Putative complexin-1, [RH, Score=99.4, Expect=2e-27]} {Smed: dd_Smed_v6_9918_0_1, dd_Smed_v6_9918_0_1, [Score=94.4, Expect=2e-25]} {RNA1509_37151, RNA1509_38047} {RNA1310_51275, RNA1509_38047} {RNA1509_38047, RNA815_22799}
55. MligTC455_39467 6156 128.24 Mlig455_066728, Mlig455_066742

Neo: -

Age: logFC(26M/2M)=-0.137

Region-specific R2: 2.002

Region-enriched R2: 1.402/0.00004

PC 3.255 - 0.734 - 0.722 0.991 0.808

Mlig455_066728 {REF} {Length: 4310} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=220.4]; Conserved carboxylase domain [PF02436.20, score=216.0]; Biotin carboxylase, N-terminal domain [PF00289.24, score=144.7]; Biotin carboxylase C-terminal domain [PF02785.21, score=102.8]; HMGL-like [PF00682.21, score=93.0]; Biotin-requiring enzyme [PF00364.24, score=57.9]; Biotin-lipoyl like [PF13533.8, score=28.3]; D-ala D-ala ligase C-terminus [PF07478.15, score=25.5]; ATP-grasp domain [PF02222.24, score=24.6]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=1375, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=1365, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=1419, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=1371, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=1440, Expect=0.0]} {RNA1509_292} {RNA1310_1178} {RNA815_516.1}

Mlig455_066742 {REF} {Length: 4334} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=265.4]; Biotin carboxylase, N-terminal domain [PF00289.24, score=117.2]; Biotin carboxylase C-terminal domain [PF02785.21, score=104.0]; ATP-grasp domain [PF02222.24, score=37.0]; D-ala D-ala ligase C-terminus [PF07478.15, score=34.3]; ATP-grasp domain [PF02655.16, score=18.8]; HMGL-like [PF00682.21, score=18.3]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [Score=837, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [Score=826, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [Score=839, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [Score=808, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [Score=851, Expect=0.0]} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1310_1642, RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579} {RNA1509_10828, RNA1509_18927, RNA1509_292, RNA1509_34195, RNA1509_44579, RNA815_516.1}
56. MligTC455_33832 112 2.34 Mlig455_029411

Neo: -

Age: Up-Down-Down

Region-enriched R2: 5.300/0.00016
Region-enriched R8: 4.136/0.03070

GLRA3 3.232 - - 0.753 0.703 0.965 0.811 Mlig455_029411 {REF} {Length: 3686} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=3e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=5e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=2e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=7e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=1e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_35433}
57. MligTC455_17701 1279 26.65 Mlig455_051483

Neo: -

Age: Down-Up-Up

Region-specific R2: 5.592

Region-enriched R2: 6.602/0.00000
Region-enriched R3: 2.598/0.04295

3.223 - 0.760 0.780 0.714 0.969 - Mlig455_051483 {REF} {Length: 1833} {RNA1509_14131} {RNA1310_69964.2, RNA1509_14131} {RNA1509_14131, RNA815_35453.1}
58. MligTC455_45051 307 6.41 Mlig455_043687, Mlig455_043755

Neo: -

Age: -

3.19 - 0.729 0.790 - 0.959 0.712

Mlig455_043687 {REF} {Length: 1460} {RNA1310_17293.1}

Mlig455_043755 {REF} {Length: 1366} {TRANSSPLICED} {RNA1310_17293.1}
59. MligTC455_33831 198 4.13 Mlig455_029369

Neo: -

Age: -

Region-enriched R2: 3.223/0.02852

Regeneration-downregulated TP: -7.340

Regeneration-depleted TP: -7.340

GLRA3 3.173 0.704 - 0.802 - 0.957 0.710 Mlig455_029369 {REF} {Length: 3665} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=149.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=84.5]} {Human: ENSG00000145451, GLRA3, glycine receptor alpha 3, [Score=257, Expect=5e-80]; ENSG00000145888, GLRA1, glycine receptor alpha 1, [Score=253, Expect=2e-78]; ENSG00000101958, GLRA2, glycine receptor alpha 2, [Score=250, Expect=4e-77]} {Mouse: ENSMUSG00000038257, Glra3, glycine receptor, alpha 3 subunit, [Score=251, Expect=2e-77]; ENSMUSG00000018589, Glra2, glycine receptor, alpha 2 subunit, [Score=249, Expect=3e-77]; ENSMUSG00000000263, Glra1, glycine receptor, alpha 1 subunit, [Score=248, Expect=1e-76]; ENSMUSG00000018595, Glra4, glycine receptor, alpha 4 subunit, [Score=243, Expect=1e-74]} {Dmel: FBgn0024963, GluClalpha, [Score=253, Expect=2e-78]} {Celegans: WBGene00000233, avr-15, GluClalpha2B protein, [Score=259, Expect=5e-81]} {Smed: dd_Smed_v6_11342_0_1, dd_Smed_v6_11342_0_1, [RH, Score=480, Expect=2e-167]} {RNA1509_35986} {RNA1310_35528} {RNA815_11925.1}
60. MligTC455_41328 417 8.68 Mlig455_057091

Neo: -

Age: Down-Up-Down

Region-enriched R2: 6.162/0.00002

2.774 - - - 0.917 0.955 0.902 Mlig455_057091 {REF} {Length: 854} {RNA1310_89414} {RNA815_40489.2}
61. MligTC455_18579 143 2.97 Mlig455_047208, Mlig455_048469

Neo: -

Age: -

GRIK2, GRIK3 2.771 - - 0.855 - 0.993 0.923

Mlig455_047208 {REF} {Length: 5413} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=92.5]; Ligand-gated ion channel [PF00060.28, score=84.4]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=49.2]} {Human: ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=194, Expect=2e-50]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=193, Expect=5e-50]; ENSG00000105737, GRIK5, glutamate ionotropic receptor kainate type subunit 5, [Score=192, Expect=2e-49]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=192, Expect=2e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=191, Expect=3e-49]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=194, Expect=1e-50]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=194, Expect=3e-50]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=191, Expect=2e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=191, Expect=2e-49]; ENSMUSG00000003378, Grik5, glutamate receptor, ionotropic, kainate 5 (gamma 2), [Score=188, Expect=2e-48]} {Dmel: FBgn0038837, CG3822, [Score=185, Expect=9e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=200, Expect=7e-53]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=341, Expect=5e-106]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}

Mlig455_048469 {REF} {Length: 3740} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=95.9]; Ligand-gated ion channel [PF00060.28, score=82.2]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=51.5]} {Human: ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=190, Expect=6e-50]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=187, Expect=5e-49]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=185, Expect=3e-48]; ENSG00000149403, GRIK4, glutamate ionotropic receptor kainate type subunit 4, [Score=184, Expect=1e-47]} {Mouse: ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=189, Expect=7e-50]; ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=187, Expect=6e-49]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=185, Expect=2e-48]; ENSMUSG00000032017, Grik4, glutamate receptor, ionotropic, kainate 4, [Score=183, Expect=9e-48]} {Dmel: FBgn0038837, CG3822, [Score=183, Expect=4e-48]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=183, Expect=3e-48]} {Smed: dd_Smed_v6_17503_0_1, dd_Smed_v6_17503_0_1, [Score=338, Expect=6e-108]} {RNA1509_47157} {RNA1310_18671} {RNA815_30308}
62. MligTC455_54338 49 1.02 Mlig455_056485

Neo: -

Age: Up-Down-Down

PKDREJ 2.764 - - 0.858 - 0.980 0.926 Mlig455_056485 {REF} {Length: 11174} {Pfam: Polycystin cation channel [PF08016.14, score=290.0]; REJ domain [PF02010.17, score=90.7]; PLAT/LH2 domain [PF01477.25, score=67.3]; PKD domain [PF00801.22, score=47.7]; Ion transport protein [PF00520.33, score=40.1]; PKD domain [PF18911.2, score=29.8]; GPCR proteolysis site, GPS, motif [PF01825.23, score=27.4]; WSC domain [PF01822.21, score=27.0]} {Human: ENSG00000130943, PKDREJ, polycystin family receptor for egg jelly, [Score=280, Expect=1e-74]} {Mouse: ENSMUSG00000034416, Pkd1l2, polycystic kidney disease 1 like 2, [Score=307, Expect=8e-83]} {Dmel: FBgn0041195, Pkd2, Polycystic kidney disease 2, [Score=151, Expect=3e-36]} {Celegans: WBGene00003058, lov-1, Location of vulva defective 1, [RH, Score=302, Expect=1e-81]} {Smed: dd_Smed_v6_15525_0_2, dd_Smed_v6_15525_0_2, [RH, Score=1844, Expect=0.0]} {RNA1509_16432} {RNA1310_1236} {RNA815_2411}
63. MligTC455_41396 187 3.9 Mlig455_012937, Mlig455_031470

Neo: -

Age: -

Region-enriched R2: 4.167/0.01146

2.747 - - 0.871 - 0.964 0.912

Mlig455_012937 {REF} {Length: 1911} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [Score=46.6, Expect=1e-06]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}

Mlig455_031470 {REF} {Length: 1745} {Dmel: FBgn0083971, CG34135, [RH, Score=60.1, Expect=1e-10]} {Smed: dd_Smed_v6_11196_0_1, dd_Smed_v6_11196_0_1, [RH, Score=96.3, Expect=3e-23]} {RNA1509_16138} {RNA1310_24329} {RNA815_11818}
64. MligTC455_32028 19 0.39 Mlig455_019343, Mlig455_019346

Neo: -

Age: -

GRIA2 2.745 - - 0.877 - 0.966 0.902

Mlig455_019343 {REF} {Length: 3241} {Pfam: Ligand-gated ion channel [PF00060.28, score=96.6]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=57.9]; Receptor family ligand binding region [PF01094.30, score=49.1]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=19.0]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=150, Expect=1e-36]; ENSG00000164418, GRIK2, glutamate ionotropic receptor kainate type subunit 2, [Score=149, Expect=2e-36]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=146, Expect=2e-35]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=144, Expect=9e-35]; ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=144, Expect=1e-34]} {Mouse: ENSMUSG00000056073, Grik2, glutamate receptor, ionotropic, kainate 2 (beta 2), [Score=150, Expect=5e-37]; ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=150, Expect=8e-37]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=145, Expect=3e-35]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=145, Expect=3e-35]; ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=144, Expect=5e-35]} {Dmel: FBgn0039927, CG11155, [Score=158, Expect=1e-39]} {Celegans: WBGene00001614, glr-3, GLutamate Receptor family (AMPA), [Score=125, Expect=3e-29]} {Smed: dd_Smed_v6_31078_0_1, dd_Smed_v6_31078_0_1, [Score=250, Expect=2e-75]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.1}

Mlig455_019346 {REF} {Length: 519} {Pfam: Receptor family ligand binding region [PF01094.30, score=21.5]} {RNA1509_10728} {RNA1310_4026} {RNA815_8415.2}
65. MligTC455_16233 307 6.4 Mlig455_011368

Neo: -

Age: logFC(26M/2M)=-1.958

2.726 - - 0.847 - 0.962 0.917 Mlig455_011368 {REF} {Length: 1236} {RNA1509_44264} {RNA1310_62516} {RNA815_23574}
66. MligTC455_52120 179 3.73 Mlig455_024423, Mlig455_024577

Neo: -

Age: Down-Up-Down

Region-enriched R2: 4.068/0.01755

POU4F3 2.723 - - 0.863 - 0.959 0.901

Mlig455_024423 {REF} {Length: 1288} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}

Mlig455_024577 {REF} {Length: 1325} {TRANSSPLICED} {Pfam: Pou domain - N-terminal to homeobox domain [PF00157.19, score=104.8]; Homeodomain [PF00046.31, score=60.9]} {Human: ENSG00000091010, POU4F3, POU class 4 homeobox 3, [Score=212, Expect=1e-65]; ENSG00000152192, POU4F1, POU class 4 homeobox 1, [Score=211, Expect=2e-64]} {Mouse: ENSMUSG00000024497, Pou4f3, POU domain, class 4, transcription factor 3, [Score=212, Expect=7e-66]; ENSMUSG00000048349, Pou4f1, POU domain, class 4, transcription factor 1, [Score=211, Expect=2e-64]} {Dmel: FBgn0000028, acj6, abnormal chemosensory jump 6, [Score=209, Expect=2e-64]} {Celegans: WBGene00006818, unc-86, Transcription factor unc-86, [Score=188, Expect=4e-57]} {Smed: dd_Smed_v6_30562_0_1, dd_Smed_v6_30562_0_1, [Score=208, Expect=2e-64]} {RNA1509_57422} {RNA1310_23131} {RNA815_34447}
67. MligTC455_42513 70 1.45 Mlig455_023063, Mlig455_023065

Neo: -

Age: -

KCNC2 2.716 - - 0.829 - 0.981 0.906

Mlig455_023063 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}

Mlig455_023065 {REF} {Length: 2276} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.7]; Ion channel [PF07885.18, score=37.0]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=7e-87]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=280, Expect=4e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=271, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=4e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=271, Expect=3e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=285, Expect=3e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=4e-94]} {Smed: dd_Smed_v6_13250_0_2, dd_Smed_v6_13250_0_2, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}
68. MligTC455_06015 22 0.45 Mlig455_025599

Neo: -

Age: -

2.712 - - 0.841 - 0.954 0.917 Mlig455_025599 {REF} {Length: 4401} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=101.9]; WSC domain [PF01822.21, score=18.9]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=50.8, Expect=3e-06]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=59.7, Expect=4e-09]}
69. MligTC455_17806 20 0.42 Mlig455_044877

Neo: -

Age: -

2.701 - - 0.831 - 0.979 0.891 Mlig455_044877 {REF} {Length: 1723} {Pfam: F5/8 type C domain [PF00754.27, score=29.9]} {Smed: dd_Smed_v6_83746_0_1, dd_Smed_v6_83746_0_1, [RH, Score=67.8, Expect=2e-14]} {RNA1310_72359} {RNA815_40265}
70. MligTC455_19660 1113 23.18 Mlig455_042835, Mlig455_045853, Mlig455_045869

Neo: -

Age: -

Region-enriched R2: 7.811/0.00000
Region-enriched R3: 5.032/0.00323
Region-enriched R5: 3.512/0.04347

CEP164 2.683 - - - 0.872 0.983 0.828

Mlig455_042835 {REF} {Length: 1693} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=69.3, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=5e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045853 {REF} {Length: 1697} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}

Mlig455_045869 {REF} {Length: 1704} {Pfam: WW domain [PF00397.28, score=23.4]} {Human: ENSG00000110274, CEP164, centrosomal protein 164, [Score=68.9, Expect=5e-12]} {Mouse: ENSMUSG00000043987, Cep164, centrosomal protein 164, [Score=71.2, Expect=7e-13]} {Smed: dd_Smed_v6_12228_0_1, dd_Smed_v6_12228_0_1, [Score=73.6, Expect=6e-14]} {RNA1310_28636} {RNA815_10722}
71. MligTC455_35259 2265 47.19 Mlig455_040978

Neo: -

Age: Up-Down-Down

Region-specific R2: 2.606

Region-enriched R2: 1.588/0.00387

ADGRL2 2.682 - - 0.807 - 0.972 0.903 Mlig455_040978 {REF} {Length: 10808} {TRANSSPLICED} {Pfam: PDZ domain [PF00595.26, score=86.9]; 7 transmembrane receptor (Secretin family) [PF00002.26, score=76.2]; PDZ domain [PF17820.3, score=67.3]; GPCR proteolysis site, GPS, motif [PF01825.23, score=52.3]; PDZ domain [PF13180.8, score=36.4]; ZU5 domain [PF00791.22, score=30.8]; Guanylate kinase [PF00625.23, score=22.4]} {Human: ENSG00000117114, ADGRL2, adhesion G protein-coupled receptor L2, [RH, Score=174, Expect=1e-42]} {Mouse: ENSMUSG00000034917, Tjp3, tight junction protein 3, [RH, Score=172, Expect=9e-43]} {Dmel: FBgn0262614, pyd, polychaetoid, [RH, Score=232, Expect=8e-61]} {Celegans: WBGene00013683, zoo-1, ZO-1 (Zonula Occludens tight junctional protein) Ortholog, [Score=174, Expect=4e-43]} {Smed: dd_Smed_v6_8425_0_1, dd_Smed_v6_8425_0_1, [RH, Score=833, Expect=0.0]} {RNA1509_17602, RNA1509_52679, RNA1509_58629} {RNA1310_236.2, RNA1509_17602, RNA1509_58629} {RNA1509_17602, RNA1509_58629, RNA815_77.1}
72. MligTC455_41012 3127 65.15 Mlig455_040493

Neo: -

Age: -

CCDC173 2.68 - - - 0.880 0.952 0.848 Mlig455_040493 {REF} {Length: 2075} {TRANSSPLICED} {Pfam: Trichohyalin-plectin-homology domain [PF13868.8, score=74.4]} {Human: ENSG00000154479, CCDC173, coiled-coil domain containing 173, [RH, Score=196, Expect=4e-55]} {Mouse: ENSMUSG00000070883, Ccdc173, coiled-coil domain containing 173, [RH, Score=176, Expect=6e-48]} {Smed: dd_Smed_v6_8917_0_1, dd_Smed_v6_8917_0_1, [RH, Score=391, Expect=2e-130]} {RNA1509_8104, RNA1509_8434} {RNA1310_8545.2, RNA1509_8434} {RNA1509_8434, RNA815_4498}
73. MligTC455_19708 304 6.32 Mlig455_009784

Neo: -

Age: -

Region-enriched R2: 6.355/0.00039

2.678 - - 0.809 - 0.963 0.906 Mlig455_009784 {REF} {Length: 826} {Pfam: Pancreatic hormone peptide [PF00159.20, score=43.3]} {RNA1509_54211} {RNA1310_54505.1, RNA1509_54211} {RNA1509_54211, RNA815_29389}
74. MligTC455_43072 81 1.68 Mlig455_042521

Neo: -

Age: Down-Up-Down

Region-enriched R2: 5.590/0.02161

2.675 - - 0.796 - 0.957 0.922 Mlig455_042521 {REF} {Length: 1049} {RNA1509_46101} {RNA1310_32444} {RNA815_30668}
75. MligTC455_48050 2232 46.51 Mlig455_010555

Neo: -

Age: logFC(26M/2M)=-0.254

Region-specific R2: 1.866

Region-enriched R2: 1.359/0.00112

2.674 - - - 0.764 0.939 0.971 Mlig455_010555 {REF} {Length: 1509} {RNA1509_46129, RNA1509_6507} {RNA1310_26163, RNA1509_46129, RNA1509_6507} {RNA1509_46129, RNA1509_6507, RNA815_24113}
76. MligTC455_14130 101 2.11 Mlig455_028802

Neo: -

Age: -

Region-enriched R7: 4.171/0.00325

2.672 - - - 0.761 0.979 0.932 Mlig455_028802 {REF} {Length: 1282} {Pfam: Lectin C-type domain [PF00059.23, score=21.4]} {RNA1509_20946} {RNA1310_33562} {RNA815_30982}
77. MligTC455_24270 71 1.47 Mlig455_005120

Neo: -

Age: -

CHRNA7 2.667 - - 0.815 - 0.960 0.892 Mlig455_005120 {REF} {Length: 1530} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=115.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=66.6]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=148, Expect=4e-39]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=147, Expect=5e-39]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=145, Expect=4e-38]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=146, Expect=2e-38]; ENSMUSG00000032269, Htr3a, 5-hydroxytryptamine (serotonin) receptor 3A, [Score=140, Expect=1e-36]} {Dmel: FBgn0028875, nAChRalpha5, nicotinic Acetylcholine Receptor alpha5, [Score=135, Expect=5e-34]} {Celegans: WBGene00000060, acr-21, AcetylCholine Receptor, [Score=134, Expect=9e-35]} {Smed: dd_Smed_v6_8058_0_1, dd_Smed_v6_8058_0_1, [Score=133, Expect=4e-34]} {RNA1509_43533} {RNA1310_20839.2} {RNA815_22406}
78. MligTC455_29914 44 0.91 Mlig455_027923

Neo: -

Age: Down-Up-Down

Region-enriched R2: 8.096/0.00455

ANGPTL3 2.665 - - 0.838 - 0.961 0.866 Mlig455_027923 {REF} {Length: 1663} {Pfam: Fibrinogen beta and gamma chains, C-terminal globular domain [PF00147.20, score=70.5]} {Human: ENSG00000132855, ANGPTL3, angiopoietin like 3, [Score=60.5, Expect=9e-10]; ENSG00000116194, ANGPTL1, angiopoietin like 1, [Score=59.3, Expect=2e-09]; ENSG00000120332, TNN, tenascin N, [Score=58.9, Expect=3e-09]} {Mouse: ENSMUSG00000015829, Tnr, tenascin R, [Score=62.4, Expect=2e-10]} {Dmel: FBgn0031804, CG9500, [Score=76.3, Expect=6e-16]} {Smed: dd_Smed_v6_18326_0_1, dd_Smed_v6_18326_0_1, [Score=51.2, Expect=3e-07]} {RNA1509_53291} {RNA1310_58974} {RNA815_43288.3}
79. MligTC455_20390 87 1.82 Mlig455_051716

Neo: -

Age: -

SLC1A2 2.663 - - 0.807 - 0.950 0.906 Mlig455_051716 {REF} {Length: 4683} {Pfam: Sodium:dicarboxylate symporter family [PF00375.20, score=432.6]} {Human: ENSG00000110436, SLC1A2, solute carrier family 1 member 2, [RH, Score=530, Expect=0.0]} {Mouse: ENSMUSG00000005089, Slc1a2, solute carrier family 1 (glial high affinity glutamate transporter), member 2, [RH, Score=545, Expect=0.0]} {Dmel: FBgn0026439, Eaat1, Excitatory amino acid transporter 1, [RH, Score=375, Expect=4e-124]} {Celegans: WBGene00001620, glt-1, Excitatory amino acid transporter, [RH, Score=517, Expect=1e-179]} {Smed: dd_Smed_v6_7570_0_1, dd_Smed_v6_7570_0_1, [RH, Score=611, Expect=0.0]} {RNA1509_31315} {RNA1310_5180} {RNA815_8754}
80. MligTC455_24761 13620 283.74 Mlig455_039154

Neo: -

Age: -

Region-enriched R7: 1.855/0.00000
Region-enriched R8: 1.742/0.00000

Regeneration-depleted BL: -2.239
Regeneration-depleted R6: -2.039

2.654 0.854 0.953 0.847 - - - Mlig455_039154 {REF} {Length: 1176} {TRANSSPLICED} {RNA1509_1669, RNA1509_32817, RNA1509_47614, RNA1509_4767, RNA1509_50169} {RNA1310_33888, RNA1509_1669, RNA1509_32817, RNA1509_47614, RNA1509_4767, RNA1509_50169} {RNA1509_1669, RNA1509_32817, RNA1509_47614, RNA1509_4767, RNA1509_50169, RNA815_17199}
81. MligTC455_05098 127 2.65 Mlig455_009525, Mlig455_009531

Neo: -

Age: Up-Down-Down

Region-enriched R4: 4.095/0.01821

KCNH7 2.648 - - 0.834 - 0.974 0.840

Mlig455_009525 {REF} {Length: 2109} {Pfam: Ion transport protein [PF00520.33, score=111.8]; Ion channel [PF07885.18, score=46.1]; Cyclic nucleotide-binding domain [PF00027.31, score=36.3]; Transcription factor IIA, alpha/beta subunit [PF03153.15, score=29.8]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=528, Expect=4e-176]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=509, Expect=2e-170]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=505, Expect=9e-167]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=527, Expect=4e-175]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=510, Expect=3e-171]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=504, Expect=9e-167]} {Dmel: FBgn0003353, sei, seizure, [Score=507, Expect=2e-171]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=496, Expect=1e-169]} {Smed: dd_Smed_v6_12978_0_1, dd_Smed_v6_12978_0_1, [Score=608, Expect=0.0]} {RNA1509_56964} {RNA1310_41939} {RNA815_5858.1}

Mlig455_009531 {REF} {Length: 3631} {Pfam: Ion transport protein [PF00520.33, score=110.4]; Ion channel [PF07885.18, score=45.2]; Cyclic nucleotide-binding domain [PF00027.31, score=43.3]} {Human: ENSG00000184611, KCNH7, potassium voltage-gated channel subfamily H member 7, [Score=619, Expect=0.0]; ENSG00000173826, KCNH6, potassium voltage-gated channel subfamily H member 6, [Score=597, Expect=0.0]; ENSG00000055118, KCNH2, potassium voltage-gated channel subfamily H member 2, [Score=596, Expect=0.0]} {Mouse: ENSMUSG00000059742, Kcnh7, potassium voltage-gated channel, subfamily H (eag-related), member 7, [Score=617, Expect=0.0]; ENSMUSG00000001901, Kcnh6, potassium voltage-gated channel, subfamily H (eag-related), member 6, [Score=602, Expect=0.0]; ENSMUSG00000038319, Kcnh2, potassium voltage-gated channel, subfamily H (eag-related), member 2, [Score=596, Expect=0.0]} {Dmel: FBgn0003353, sei, seizure, [Score=591, Expect=0.0]} {Celegans: WBGene00006830, unc-103, Potassium voltage-gated channel unc-103, [Score=579, Expect=0.0]} {Smed: dd_Smed_v6_12978_0_4, dd_Smed_v6_12978_0_4, [RH, Score=716, Expect=0.0]} {RNA1509_56964} {RNA1310_23186, RNA1509_56964} {RNA1509_56964, RNA815_5858.2}
82. MligTC455_11452 34 0.7 Mlig455_059243

Neo: -

Age: -

2.646 - - - 0.768 0.965 0.913 Mlig455_059243 {REF} {Length: 1221} {Pfam: Concanavalin A-like lectin/glucanases superfamily [PF13385.8, score=20.8]} {RNA1509_24218} {RNA1310_25312.1} {RNA815_12390}
83. MligTC455_40325 103 2.15 Mlig455_013035

Neo: -

Age: -

2.642 - - - 0.765 0.964 0.913 Mlig455_013035 {REF} {Length: 653} {RNA1509_20946} {RNA1310_44606} {RNA815_35640}
84. MligTC455_32445 285 5.93 Mlig455_041727, Mlig455_042282

Neo: -

Age: -

ANK2 2.633 - 0.767 - - 0.965 0.901

Mlig455_041727 {REF} {Length: 4931} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.7]; Ankyrin repeats (many copies) [PF13637.8, score=238.3]; Ankyrin repeat [PF00023.32, score=223.0]; Ankyrin repeats (many copies) [PF13857.8, score=214.9]; Ankyrin repeat [PF13606.8, score=201.4]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=211, Expect=1e-54]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=290, Expect=2e-80]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=210, Expect=2e-54]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=489, Expect=7e-151]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=745, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1, RNA1509_18945} {RNA1509_18945, RNA815_450.1}

Mlig455_042282 {REF} {Length: 4940} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=273.8]; Ankyrin repeats (many copies) [PF13637.8, score=232.4]; Ankyrin repeat [PF00023.32, score=218.4]; Ankyrin repeats (many copies) [PF13857.8, score=210.6]; Ankyrin repeat [PF13606.8, score=197.5]; Ion transport protein [PF00520.33, score=46.6]} {Human: ENSG00000145362, ANK2, ankyrin 2, [Score=214, Expect=2e-55]} {Mouse: ENSMUSG00000032826, Ank2, ankyrin 2, brain, [Score=204, Expect=1e-52]; ENSMUSG00000069601, Ank3, ankyrin 3, epithelial, [Score=201, Expect=2e-51]} {Dmel: FBgn0011747, Ank, Ankyrin, [Score=205, Expect=6e-53]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=487, Expect=5e-150]} {Smed: dd_Smed_v6_6201_0_2, dd_Smed_v6_6201_0_2, [RH, Score=736, Expect=0.0]} {RNA1509_18945} {RNA1310_1506.1} {RNA815_8298}
85. MligTC455_41595 483 10.07 Mlig455_065096

Neo: -

Age: -

2.632 - - 0.783 - 0.954 0.895 Mlig455_065096 {REF} {Length: 1103} {RNA1310_35732} {RNA815_16408}
86. MligTC455_18564 196 4.08 Mlig455_063527

Neo: -

Age: -

Region-enriched R2: 2.416/0.01839

PRKG2 2.631 - 0.757 - - 0.952 0.922 Mlig455_063527 {REF} {Length: 2971} {Pfam: Protein kinase domain [PF00069.27, score=212.4]; Cyclic nucleotide-binding domain [PF00027.31, score=135.9]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=103.7]; Kinase-like [PF14531.8, score=24.8]} {Human: ENSG00000138669, PRKG2, protein kinase cGMP-dependent 2, [RH, Score=653, Expect=0.0]} {Mouse: ENSMUSG00000029334, Prkg2, protein kinase, cGMP-dependent, type II, [RH, Score=651, Expect=0.0]} {Dmel: FBgn0000442, Pkg21D, Protein kinase, cGMP-dependent at 21D, [RH, Score=662, Expect=0.0]} {Celegans: WBGene00001173, egl-4, cGMP-dependent protein kinase egl-4, [Score=655, Expect=0.0]} {Smed: dd_Smed_v6_6967_0_1, dd_Smed_v6_6967_0_1, [RH, Score=645, Expect=0.0]} {RNA1509_38353} {RNA1310_8466, RNA1509_38353} {RNA1509_38353, RNA815_6313}
87. MligTC455_24302 149 3.11 Mlig455_035632

Neo: -

Age: Up-Down-Up

KCNQ5 2.628 - - 0.759 - 0.968 0.901 Mlig455_035632 {REF} {Length: 2263} {Pfam: KCNQ voltage-gated potassium channel [PF03520.16, score=124.6]} {Human: ENSG00000185760, KCNQ5, potassium voltage-gated channel subfamily Q member 5, [Score=122, Expect=1e-28]; ENSG00000117013, KCNQ4, potassium voltage-gated channel subfamily Q member 4, [Score=121, Expect=2e-28]} {Mouse: ENSMUSG00000028033, Kcnq5, potassium voltage-gated channel, subfamily Q, member 5, [Score=121, Expect=1e-28]; ENSMUSG00000028631, Kcnq4, potassium voltage-gated channel, subfamily Q, member 4, [Score=119, Expect=4e-28]} {Dmel: FBgn0033494, KCNQ, KCNQ potassium channel, [Score=175, Expect=1e-46]} {Celegans: WBGene00002235, kqt-3, KQT-3 potassium channel; Potassium channel, KvQLT family, [Score=110, Expect=1e-25]} {Smed: dd_Smed_v6_17359_0_2, dd_Smed_v6_17359_0_2, [Score=186, Expect=2e-52]} {RNA1509_34272} {RNA1310_3730.1} {RNA815_2787}
88. MligTC455_40118 72 1.5 Mlig455_001236

Neo: -

Age: -

KCNIP4 2.628 - - 0.740 - 0.960 0.928 Mlig455_001236 {REF} {Length: 1284} {Pfam: EF-hand domain pair [PF13499.8, score=42.4]; EF hand [PF00036.34, score=38.6]; EF-hand domain [PF13405.8, score=33.5]; EF hand [PF13202.8, score=31.2]; EF-hand domain pair [PF13833.8, score=28.7]} {Human: ENSG00000185774, KCNIP4, potassium voltage-gated channel interacting protein 4, [Score=122, Expect=2e-32]; ENSG00000182132, KCNIP1, potassium voltage-gated channel interacting protein 1, [Score=122, Expect=2e-32]; ENSG00000115041, KCNIP3, potassium voltage-gated channel interacting protein 3, [Score=119, Expect=1e-30]} {Mouse: ENSMUSG00000053519, Kcnip1, Kv channel-interacting protein 1, [Score=124, Expect=5e-33]; ENSMUSG00000029088, Kcnip4, Kv channel interacting protein 4, [Score=122, Expect=1e-32]} {Dmel: FBgn0013303, Nca, Neurocalcin, [Score=100, Expect=6e-25]} {Celegans: WBGene00003563, ncs-1, Neuronal calcium sensor 1, [Score=103, Expect=5e-26]} {Smed: dd_Smed_v6_9727_0_1, dd_Smed_v6_9727_0_1, [Score=122, Expect=8e-33]} {RNA1310_43225} {RNA815_33406}
89. MligTC455_40654 676 14.08 Mlig455_056785

Neo: -

Age: logFC(26M/2M)=-0.402

CCDC63 2.627 - - 0.808 - 0.962 0.857 Mlig455_056785 {REF} {Length: 2093} {TRANSSPLICED} {Pfam: Initiation control protein YabA [PF06156.15, score=20.5]} {Human: ENSG00000173093, CCDC63, coiled-coil domain containing 63, [RH, Score=190, Expect=9e-53]} {Mouse: ENSMUSG00000043036, Ccdc63, coiled-coil domain containing 63, [RH, Score=179, Expect=7e-49]} {Dmel: FBgn0038452, CG14905, [RH, Score=168, Expect=6e-46]} {Smed: dd_Smed_v6_4191_0_1, dd_Smed_v6_4191_0_1, [RH, Score=442, Expect=7e-150]} {RNA1509_17628} {RNA1310_12386, RNA1509_17628} {RNA1509_17628, RNA815_7054}
90. MligTC455_13975 63 1.31 Mlig455_070810

Neo: -

Age: -

Region-enriched R2: 7.513/0.00519

2.614 - - 0.808 - 0.961 0.845 Mlig455_070810 {REF} {Length: 1542} {Pfam: Otopetrin [PF03189.15, score=108.9]} {Dmel: FBgn0031514, CG3332, [Score=74.3, Expect=3e-14]} {Celegans: WBGene00015035, otpl-1, OToPetrin-Like, [Score=47.8, Expect=9e-06]} {Smed: dd_Smed_v6_13612_0_3, dd_Smed_v6_13612_0_3, [Score=119, Expect=2e-29]} {RNA1310_93602} {RNA815_48323}
91. MligTC455_51051 233 4.85 Mlig455_046293

Neo: -

Age: -

2.609 - - - 0.728 0.962 0.919 Mlig455_046293 {REF} {Length: 1585} {RNA1310_32253}
92. MligTC455_49898 4613 96.09 Mlig455_029036

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.488

2.602 - - - 0.912 0.956 0.734 Mlig455_029036 {REF} {Length: 1396} {TRANSSPLICED} {RNA1509_13089, RNA1509_3685, RNA1509_42126, RNA1509_8262} {RNA1310_21028, RNA1509_13089, RNA1509_3685, RNA1509_42126, RNA1509_8262} {RNA1509_13089, RNA1509_3685, RNA1509_42126, RNA1509_8262, RNA815_9990.2}
93. MligTC455_15330 373 7.77 Mlig455_020220

Neo: -

Age: Down-Up-Up, logFC(26M/2M)=0.289

2.599 - 0.719 - - 0.967 0.913 Mlig455_020220 {REF} {Length: 2115} {Pfam: Fas apoptotic inhibitory molecule (FAIM1) [PF06905.15, score=41.4]} {Smed: dd_Smed_v6_4798_0_1, dd_Smed_v6_4798_0_1, [RH, Score=82.0, Expect=3e-20]} {RNA1509_28885, RNA1509_54654} {RNA1310_42962.2, RNA1509_28885, RNA1509_54654} {RNA1509_28885, RNA1509_54654, RNA815_23071}
94. MligTC455_24523 144 2.99 Mlig455_010636, Mlig455_010724

Neo: -

Age: -

Region-enriched R2: 9.355/0.00000

RGS6 2.593 - - 0.873 - 0.982 0.738

Mlig455_010636 {REF} {Length: 2512} {Pfam: Regulator of G-protein signalling DHEX domain [PF18148.3, score=118.4]; Regulator of G protein signaling domain [PF00615.21, score=116.4]; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) [PF00610.23, score=31.3]} {Human: ENSG00000182732, RGS6, regulator of G protein signaling 6, [Score=301, Expect=3e-95]} {Mouse: ENSMUSG00000021219, Rgs6, regulator of G-protein signaling 6, [Score=299, Expect=2e-94]; ENSMUSG00000026527, Rgs7, regulator of G protein signaling 7, [Score=290, Expect=6e-91]} {Dmel: FBgn0259927, CG42450, [RH, Score=327, Expect=2e-98]} {Celegans: WBGene00001145, eat-16, [Score=217, Expect=1e-63]} {Smed: dd_Smed_v6_5311_0_1, dd_Smed_v6_5311_0_1, [RH, Score=384, Expect=1e-127]} {RNA1509_59108} {RNA1310_13711, RNA1509_59108} {RNA1509_59108, RNA815_9935}

Mlig455_010724 {REF} {Length: 2512} {Pfam: Regulator of G-protein signalling DHEX domain [PF18148.3, score=118.4]; Regulator of G protein signaling domain [PF00615.21, score=113.1]; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) [PF00610.23, score=31.3]} {Human: ENSG00000182732, RGS6, regulator of G protein signaling 6, [Score=299, Expect=2e-94]} {Mouse: ENSMUSG00000021219, Rgs6, regulator of G-protein signaling 6, [Score=297, Expect=2e-93]; ENSMUSG00000026527, Rgs7, regulator of G protein signaling 7, [Score=287, Expect=4e-90]} {Dmel: FBgn0259927, CG42450, [RH, Score=324, Expect=1e-97]} {Celegans: WBGene00001145, eat-16, [Score=214, Expect=8e-63]} {Smed: dd_Smed_v6_5311_0_1, dd_Smed_v6_5311_0_1, [RH, Score=382, Expect=8e-127]} {RNA1509_59108} {RNA1310_13711} {RNA815_9935}
95. MligTC455_18787 963 20.06 Mlig455_014022

Neo: -

Age: -

Region-enriched R2: 1.334/0.03482

STRC 2.585 - - - 0.722 0.981 0.882 Mlig455_014022 {REF} {Length: 5754} {Human: ENSG00000242866, STRC, stereocilin, [RH, Score=76.3, Expect=4e-13]} {Mouse: ENSMUSG00000033498, Strc, stereocilin, [RH, Score=80.9, Expect=1e-14]} {RNA1509_4378} {RNA1310_1493.1, RNA1509_4378} {RNA1509_4378, RNA815_804}
96. MligTC455_52656 121 2.51 Mlig455_062381, Mlig455_062408

Neo: -

Age: Down-Up-Down

2.585 - 0.749 - - 0.979 0.857

Mlig455_062381 {REF} {Length: 2245} {RNA1310_26272} {RNA815_22826}

Mlig455_062408 {REF} {Length: 2277} {RNA1310_26272} {RNA815_37592}
97. MligTC455_24536 120 2.5 Mlig455_028895

Neo: -

Age: Up-Down-Down

TRPA1 2.573 - - 0.708 - 0.979 0.886 Mlig455_028895 {REF} {Length: 4399} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=276.9]; Ankyrin repeats (many copies) [PF13637.8, score=235.5]; Ankyrin repeats (many copies) [PF13857.8, score=187.3]; Ankyrin repeat [PF00023.32, score=185.3]; Ankyrin repeat [PF13606.8, score=184.2]; Ion transport protein [PF00520.33, score=31.3]} {Human: ENSG00000104321, TRPA1, transient receptor potential cation channel subfamily A member 1, [Score=295, Expect=6e-83]} {Mouse: ENSMUSG00000032769, Trpa1, transient receptor potential cation channel, subfamily A, member 1, [Score=277, Expect=4e-77]} {Dmel: FBgn0035934, TrpA1, Transient receptor potential cation channel A1, [Score=305, Expect=2e-86]} {Celegans: WBGene00007801, trpa-1, Transient receptor potential cation channel subfamily A member 1 homolog, [Score=276, Expect=1e-76]} {Smed: dd_Smed_v6_20683_0_1, dd_Smed_v6_20683_0_1, [RH, Score=551, Expect=2e-178]} {RNA1509_56559} {RNA1310_3837.1} {RNA815_4441}
98. MligTC455_24061 1104 23.01 Mlig455_017234

Neo: -

Age: -

SNAP25 2.565 - 0.720 - - 0.974 0.871 Mlig455_017234 {REF} {Length: 1658} {Pfam: SNAP-25 family [PF00835.21, score=41.5]} {Human: ENSG00000132639, SNAP25, synaptosome associated protein 25, [Score=219, Expect=7e-72]} {Mouse: ENSMUSG00000027273, Snap25, synaptosomal-associated protein 25, [Score=219, Expect=5e-72]} {Dmel: FBgn0266720, Snap24, Synaptosomal-associated protein 24kDa, [RH, Score=228, Expect=1e-75]} {Celegans: WBGene00004364, ric-4, Synaptosomal-associated protein, [RH, Score=257, Expect=2e-87]} {Smed: dd_Smed_v6_3977_0_1, dd_Smed_v6_3977_0_1, [RH, Score=282, Expect=2e-97]} {RNA1509_25321, RNA1509_8624} {RNA1310_24253, RNA1509_25321, RNA1509_8624} {RNA1509_25321, RNA1509_8624, RNA815_10439}
99. MligTC455_44264 1135 23.65 Mlig455_048455, Mlig455_062720

Neo: -

Age: -

Region-specific R2: 2.470

Region-enriched R2: 1.517/0.00960

2.561 - - 0.823 - 0.967 0.771

Mlig455_048455 {REF} {Length: 2873} {Pfam: Borrelia P83/100 protein [PF05262.13, score=18.8]} {Smed: dd_Smed_v6_19428_0_1, dd_Smed_v6_19428_0_1, [RH, Score=76.6, Expect=5e-15]} {RNA1509_14284} {RNA1310_10721, RNA1509_14284} {RNA1509_14284, RNA815_3648}

Mlig455_062720 {REF} {Length: 2364} {Pfam: Borrelia P83/100 protein [PF05262.13, score=19.7]} {Smed: dd_Smed_v6_19428_0_1, dd_Smed_v6_19428_0_1, [RH, Score=78.2, Expect=2e-15]} {RNA1509_14284, RNA1509_52018} {RNA1310_10721, RNA1509_52018} {RNA1509_52018, RNA815_3648}
100. MligTC455_39957 170 3.54 Mlig455_039809

Neo: -

Age: -

Region-specific R2: 4.733

Region-enriched R2: 5.232/0.00000

ADGB 2.548 - - 0.715 - 0.956 0.877 Mlig455_039809 {REF} {Length: 7010} {tRNA: Ile(TAT),pseudo, score=33.4} {Pfam: Calpain family cysteine protease [PF00648.23, score=34.1]} {Human: ENSG00000118492, ADGB, androglobin, [Score=403, Expect=6e-115]} {Mouse: ENSMUSG00000050994, Adgb, androglobin, [Score=252, Expect=4e-67]} {Celegans: WBGene00000543, clp-2, CaLPain family, [Score=73.2, Expect=1e-12]} {Smed: dd_Smed_v6_10677_0_1, dd_Smed_v6_10677_0_1, [Score=253, Expect=8e-68]} {RNA1509_15950, RNA1509_59203} {RNA1310_4821, RNA1509_59203} {RNA1509_59203, RNA815_12506}

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