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Results for MligTC455_11294

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_11294 430 8.95 Mlig455_068327

Neo: -

Age: -

Mlig455_068327 {REF} {Length: 1267} {Pfam: Gp5 C-terminal repeat (3 copies) [PF06715.14, score=21.5]} {RNA1509_10965} {RNA1310_87215.1} {RNA815_44952}

Cumulative graph for MligTC455_11294

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.697 3.624 0.47528 1.00000
RegionR2 -0.269 3.624 0.80354 1.00000
RegionR3 2.005 3.624 0.00650 0.11348
RegionR4 0.991 3.624 0.27277 0.57904
RegionR5 1.241 3.624 0.07371 0.24703
RegionR6 1.773 3.624 0.02856 0.31089
RegionR7 -2.517 3.624 0.06197 0.47806
RegionR8 -1.526 3.624 0.30710 0.93935

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 2.487 3.624 0.37122 1.00000
RegenerationR2 -0.141 3.624 0.88648 1.00000
RegenerationR3 -0.53 3.624 0.55818 0.88766
RegenerationR4 0.719 3.624 0.42695 0.82913
RegenerationR5 0.967 3.624 0.25290 0.68581
RegenerationR6 -0.32 3.624 0.72355 0.93781
RegenerationBL -0.148 3.624 0.92121 1.00000
RegenerationTP 0.215 3.624 0.90194 1.00000


Genes with expression patterns similar to MligTC455_11294

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_11294 430 8.95 Mlig455_068327

Neo: -

Age: -

6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_068327 {REF} {Length: 1267} {Pfam: Gp5 C-terminal repeat (3 copies) [PF06715.14, score=21.5]} {RNA1509_10965} {RNA1310_87215.1} {RNA815_44952}
2. MligTC455_11295 996 20.74 Mlig455_007322, Mlig455_068328

Neo: -

Age: Down-Up-Down

MTHFR 5.9 0.992 0.982 0.993 0.984 0.951 0.998

Mlig455_007322 {REF} {Length: 3390} {Pfam: Methylenetetrahydrofolate reductase [PF02219.19, score=342.2]} {Human: ENSG00000177000, MTHFR, methylenetetrahydrofolate reductase, [Score=642, Expect=0.0]} {Mouse: ENSMUSG00000029009, Mthfr, methylenetetrahydrofolate reductase, [Score=643, Expect=0.0]} {Dmel: FBgn0036157, CG7560, [Score=85.5, Expect=1e-17]} {Celegans: WBGene00015512, mthf-1, Probable methylenetetrahydrofolate reductase, [Score=538, Expect=0.0]} {Smed: dd_Smed_v6_8918_0_1, dd_Smed_v6_8918_0_1, [Score=650, Expect=0.0]} {RNA1509_10965, RNA1509_9760} {RNA1310_13357, RNA1509_10965} {RNA1509_10965, RNA815_21219}

Mlig455_068328 {REF} {Length: 5336} {Pfam: Methylenetetrahydrofolate reductase [PF02219.19, score=343.2]} {Human: ENSG00000177000, MTHFR, methylenetetrahydrofolate reductase, [Score=640, Expect=0.0]} {Mouse: ENSMUSG00000029009, Mthfr, methylenetetrahydrofolate reductase, [Score=642, Expect=0.0]} {Dmel: FBgn0036157, CG7560, [Score=85.5, Expect=1e-17]} {Celegans: WBGene00015512, mthf-1, Probable methylenetetrahydrofolate reductase, [Score=537, Expect=0.0]} {Smed: dd_Smed_v6_8918_0_1, dd_Smed_v6_8918_0_1, [Score=653, Expect=0.0]} {RNA1509_27425, RNA1509_9760} {RNA1310_13357, RNA1509_27425, RNA1509_9760} {RNA1509_27425, RNA1509_9760, RNA815_21219}
3. MligTC455_24146 2470 51.46 Mlig455_060904, Mlig455_069370, Mlig455_069388

Neo: -

Age: logFC(26M/2M)=-0.509

Region-enriched R4: 1.799/0.00434
Region-enriched R3: 1.761/0.00220
Region-enriched R5: 1.603/0.00247

2.708 0.872 - - 0.958 - 0.878

Mlig455_060904 {REF} {Length: 1171} {Pfam: WW domain-binding protein 1 [PF11669.10, score=23.0]} {RNA1509_12053, RNA1509_23482} {RNA1310_48182, RNA1509_23482} {RNA1509_23482, RNA815_22213}

Mlig455_069370 {REF} {Length: 1132} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}

Mlig455_069388 {REF} {Length: 1155} {Pfam: WW domain-binding protein 1 [PF11669.10, score=23.6]} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}
4. MligTC455_12709 342 7.13 Mlig455_000494

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=0.963

Region-enriched R3: 4.960/0.00124
Region-enriched R5: 4.179/0.00235

Regeneration-upregulated TP: 7.755

Regeneration-enriched TP: 7.755

2.698 - - 0.845 0.962 - 0.891 Mlig455_000494 {REF} {Length: 1364} {RNA1509_6476} {RNA1310_70627.1} {RNA815_15963}
5. MligTC455_16290 424 8.83 Mlig455_012500, Mlig455_012589

Neo: -

Age: logFC(26M/2M)=-0.374

Region-enriched R5: 3.298/0.00068
Region-enriched R4: 3.099/0.03444

SLC29A1 2.679 - - - 0.937 0.772 0.970

Mlig455_012500 {REF} {Length: 3324} {Pfam: Nucleoside transporter [PF01733.20, score=230.1]} {Human: ENSG00000112759, SLC29A1, solute carrier family 29 member 1 (Augustine blood group), [Score=153, Expect=1e-40]; ENSG00000198246, SLC29A3, solute carrier family 29 member 3, [Score=148, Expect=1e-38]} {Mouse: ENSMUSG00000023942, Slc29a1, solute carrier family 29 (nucleoside transporters), member 1, [Score=150, Expect=6e-40]; ENSMUSG00000024891, Slc29a2, solute carrier family 29 (nucleoside transporters), member 2, [Score=143, Expect=4e-37]} {Dmel: FBgn0263916, Ent2, Equilibrative nucleoside transporter 2, [RH, Score=264, Expect=1e-82]} {Celegans: WBGene00001320, ent-1, Equilibrative Nucleoside Transporter; Equilibrative nucleoside transporter 1, [RH, Score=240, Expect=6e-74]} {Smed: dd_Smed_v6_6848_0_1, dd_Smed_v6_6848_0_1, [Score=153, Expect=2e-41]} {RNA1509_15022, RNA1509_52896} {RNA1310_8593.2, RNA1509_15022, RNA1509_52896} {RNA1509_15022, RNA1509_52896, RNA815_5676.1}

Mlig455_012589 {REF} {Length: 3121} {Pfam: Nucleoside transporter [PF01733.20, score=230.1]} {Human: ENSG00000112759, SLC29A1, solute carrier family 29 member 1 (Augustine blood group), [Score=153, Expect=1e-40]; ENSG00000198246, SLC29A3, solute carrier family 29 member 3, [Score=148, Expect=1e-38]} {Mouse: ENSMUSG00000023942, Slc29a1, solute carrier family 29 (nucleoside transporters), member 1, [Score=150, Expect=6e-40]; ENSMUSG00000024891, Slc29a2, solute carrier family 29 (nucleoside transporters), member 2, [Score=143, Expect=4e-37]} {Dmel: FBgn0263916, Ent2, Equilibrative nucleoside transporter 2, [RH, Score=264, Expect=1e-82]} {Celegans: WBGene00001320, ent-1, Equilibrative Nucleoside Transporter; Equilibrative nucleoside transporter 1, [RH, Score=240, Expect=6e-74]} {Smed: dd_Smed_v6_6848_0_1, dd_Smed_v6_6848_0_1, [Score=153, Expect=2e-41]} {RNA1509_15022} {RNA1310_8593.2} {RNA815_5676.1}
6. MligTC455_34688 756 15.75 Mlig455_049905

Neo: -

Age: logFC(26M/2M)=0.524

Region-enriched R3: 2.234/0.00031
Region-enriched R4: 1.743/0.02090
Region-enriched R5: 1.276/0.04216

MGAM2 2.559 - - 0.960 - 0.761 0.838 Mlig455_049905 {REF} {Length: 4307} {Pfam: Glycosyl hydrolases family 31 [PF01055.28, score=486.1]; N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase [PF16863.7, score=39.1]; Galactose mutarotase-like [PF13802.8, score=25.5]} {Human: ENSG00000257743, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000278563, MGAM2, maltase-glucoamylase 2 (putative), [Score=632, Expect=0.0]; ENSG00000257335, MGAM, maltase-glucoamylase, [Score=626, Expect=0.0]; ENSG00000282607, MGAM, maltase-glucoamylase, [Score=617, Expect=0.0]; ENSG00000090402, SI, sucrase-isomaltase, [Score=605, Expect=0.0]} {Mouse: ENSMUSG00000068587, Mgam, maltase-glucoamylase, [Score=644, Expect=0.0]; ENSMUSG00000027790, Sis, sucrase isomaltase (alpha-glucosidase), [Score=631, Expect=0.0]} {Dmel: FBgn0027588, GCS2alpha, Glucosidase 2 alpha subunit, [Score=226, Expect=1e-61]} {Celegans: WBGene00017071, aagr-1, Acid Alpha Glucosidase Relate, [RH, Score=476, Expect=5e-153]} {Smed: dd_Smed_v6_1062_0_1, dd_Smed_v6_1062_0_1, [Score=530, Expect=2e-174]} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1310_4558.1, RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412} {RNA1509_22266, RNA1509_2280, RNA1509_24970, RNA1509_29248, RNA1509_32202, RNA1509_33412, RNA815_1348}
7. MligTC455_24191 167 3.47 Mlig455_036990

Neo: -

Age: logFC(26M/2M)=0.434

Region-enriched R5: 2.098/0.03929

GCKR 2.554 - - 0.825 - 0.760 0.969 Mlig455_036990 {REF} {Length: 3658} {TRANSSPLICED} {Pfam: Zinc finger, C2H2 type [PF00096.28, score=29.6]} {Human: ENSG00000084734, GCKR, glucokinase regulator, [RH, Score=150, Expect=6e-37]} {Mouse: ENSMUSG00000059434, Gckr, glucokinase regulatory protein, [RH, Score=146, Expect=7e-36]} {Dmel: FBgn0259789, zld, zelda, [Score=54.7, Expect=6e-07]} {Celegans: WBGene00003847, blmp-1, B lymphocyte-induced maturation protein 1 homolog, [Score=65.1, Expect=2e-10]} {Smed: dd_Smed_v6_5558_0_1, dd_Smed_v6_5558_0_1, [RH, Score=75.5, Expect=3e-14]} {RNA1509_51386} {RNA1310_15402} {RNA815_4323.1}
8. MligTC455_49086 274 5.71 Mlig455_011515

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.627

Region-enriched R3: 2.565/0.00416
Region-enriched R5: 2.441/0.00091
Region-enriched R6: 2.339/0.03988

RAC1 2.44 - - - 0.957 0.722 0.761 Mlig455_011515 {REF} {Length: 1740} {Pfam: Ras family [PF00071.24, score=159.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=69.7]; ADP-ribosylation factor family [PF00025.23, score=26.0]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=221, Expect=2e-73]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=218, Expect=1e-72]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=217, Expect=4e-72]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=221, Expect=1e-73]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=217, Expect=3e-72]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=217, Expect=3e-72]} {Dmel: FBgn0010333, Rac1, [Score=221, Expect=3e-74]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=226, Expect=5e-76]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=223, Expect=6e-75]} {RNA1509_17203} {RNA1310_15755.1} {RNA815_8276}
9. MligTC455_40877 940 19.59 Mlig455_028254

Neo: -

Age: -

Region-enriched R4: 1.189/0.01108
Region-enriched R3: 1.015/0.01751

ETHE1 1.908 - - - 0.979 - 0.929 Mlig455_028254 {REF} {Length: 1819} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=325, Expect=1e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=322, Expect=1e-111]} {Dmel: FBgn0050022, CG30022, [Score=290, Expect=1e-98]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=285, Expect=3e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=317, Expect=9e-110]} {RNA1509_7310} {RNA1310_16001.1, RNA1509_7310} {RNA1509_7310, RNA815_19195}
10. MligTC455_19520 711 14.82 Mlig455_018524

Neo: -

Age: logFC(26M/2M)=-0.243

PTDSS2 1.906 - - - 0.975 - 0.931 Mlig455_018524 {REF} {Length: 3134} {TRANSSPLICED} {Pfam: Phosphatidyl serine synthase [PF03034.17, score=388.0]} {Human: ENSG00000174915, PTDSS2, phosphatidylserine synthase 2, [Score=480, Expect=7e-167]} {Mouse: ENSMUSG00000025495, Ptdss2, phosphatidylserine synthase 2, [Score=483, Expect=3e-168]} {Dmel: FBgn0037010, CG4825, [Score=269, Expect=1e-84]} {Celegans: WBGene00012095, pssy-2, PhosphatidylSerine SYnthase, [Score=275, Expect=3e-86]} {Smed: dd_Smed_v6_7678_0_1, dd_Smed_v6_7678_0_1, [RH, Score=577, Expect=0.0]} {RNA1509_10186, RNA1509_15443, RNA1509_19161, RNA1509_25562, RNA1509_26982} {RNA1310_5581, RNA1509_10186, RNA1509_15443, RNA1509_19161, RNA1509_25562, RNA1509_26982} {RNA1509_10186, RNA1509_15443, RNA1509_19161, RNA1509_25562, RNA1509_26982, RNA815_3642.1}
11. MligTC455_24869 3528 73.49 Mlig455_039885, Mlig455_039903, Mlig455_039939

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.614/0.00079

MRC1 1.824 - - - 0.970 - 0.854

Mlig455_039885 {REF} {Length: 6516} {Pfam: Lectin C-type domain [PF00059.23, score=685.5]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=75.5]; Extracellular link domain [PF00193.19, score=22.7]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=492, Expect=6e-146]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=494, Expect=1e-146]} {Dmel: FBgn0040102, lectin-24Db, [RH, Score=72.0, Expect=1e-12]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [RH, Score=95.1, Expect=1e-20]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [RH, Score=228, Expect=4e-60]} {RNA1509_240} {RNA1310_205.1} {RNA815_95}

Mlig455_039903 {REF} {Length: 6532} {Pfam: Lectin C-type domain [PF00059.23, score=559.4]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=65.7]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=365, Expect=9e-104]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=348, Expect=5e-98]} {Dmel: FBgn0040102, lectin-24Db, [RH, Score=71.6, Expect=1e-12]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [RH, Score=94.0, Expect=2e-20]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=202, Expect=2e-52]} {RNA1509_23542, RNA1509_240, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472} {RNA1310_205.1, RNA1509_23542, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472} {RNA1509_23542, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472, RNA815_95}

Mlig455_039939 {REF} {Length: 6496} {Pfam: Lectin C-type domain [PF00059.23, score=267.5]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=42.5]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=180, Expect=2e-46]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=172, Expect=6e-44]} {Dmel: FBgn0035199, tfc, triforce, [Score=60.8, Expect=2e-10]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [Score=89.0, Expect=4e-19]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=99.0, Expect=4e-21]} {RNA1509_240} {RNA1310_205.1} {RNA815_95}
12. MligTC455_48968 2833 59.01 Mlig455_068344

Neo: -

Age: -

1.738 - - - 0.966 - 0.772 Mlig455_068344 {REF} {Length: 680} {TRANSSPLICED} {Pfam: Type III secretion system lipoprotein chaperone (YscW) [PF09619.12, score=24.2]} {RNA1509_52356} {RNA1310_19739.1} {RNA815_20380}
13. MligTC455_23197 112 2.33 Mlig455_007758

Neo: -

Age: -

Region-enriched R5: 2.659/0.03486

Regeneration-upregulated R2: 4.954

Regeneration-enriched R2: 4.954

LRRK2 1.733 - - - - 0.778 0.955 Mlig455_007758 {REF} {Length: 11346} {Pfam: Protein kinase domain [PF00069.27, score=143.6]; Leucine rich repeat [PF13855.8, score=113.0]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=112.4]; C-terminal of Roc, COR, domain [PF16095.7, score=87.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=84.7]; Leucine Rich repeats (2 copies) [PF12799.9, score=66.1]; Ras family [PF00071.24, score=41.9]; Leucine-rich repeat [PF14580.8, score=22.1]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [RH, Score=787, Expect=0.0]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [RH, Score=780, Expect=0.0]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=248, Expect=4e-65]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=179, Expect=2e-44]} {Smed: dd_Smed_v6_7343_0_1, dd_Smed_v6_7343_0_1, [RH, Score=670, Expect=0.0]} {RNA1509_6991} {RNA1310_771.1} {RNA815_2219.1}
14. MligTC455_40148 859 17.9 Mlig455_017851, Mlig455_047871

Neo: -

Age: -

Region-enriched R4: 2.301/0.00625

1.727 - - - 0.966 - 0.761

Mlig455_017851 {REF} {Length: 2678} {RNA1509_11917, RNA1509_28007, RNA1509_35856} {RNA1310_13722, RNA1509_11917, RNA1509_28007, RNA1509_35856} {RNA1509_11917, RNA1509_28007, RNA1509_35856, RNA815_5229}

Mlig455_047871 {REF} {Length: 1990} {RNA1509_11917} {RNA1310_13722} {RNA815_5229}
15. MligTC455_27415 405 8.43 Mlig455_000570, Mlig455_030368, Mlig455_030416

Neo: -

Age: -

Region-enriched R4: 3.950/0.00080
Region-enriched R5: 2.365/0.01333

NADK 1.718 - 0.762 - - - 0.956

Mlig455_000570 {REF} {Length: 2353} {Pfam: ATP-NAD kinase C-terminal domain [PF20143.1, score=116.1]; ATP-NAD kinase N-terminal domain [PF01513.23, score=36.3]} {Human: ENSG00000008130, NADK, NAD kinase, [RH, Score=264, Expect=2e-82]} {Mouse: ENSMUSG00000029063, Nadk, NAD kinase, [Score=265, Expect=2e-85]} {Dmel: FBgn0053156, CG33156, [Score=263, Expect=1e-84]} {Smed: dd_Smed_v6_8020_0_1, dd_Smed_v6_8020_0_1, [Score=179, Expect=2e-52]} {RNA1509_52179} {RNA1310_11933} {RNA815_29661}

Mlig455_030368 {REF} {Length: 2306} {Pfam: ATP-NAD kinase C-terminal domain [PF20143.1, score=116.3]; ATP-NAD kinase N-terminal domain [PF01513.23, score=36.5]} {Human: ENSG00000008130, NADK, NAD kinase, [RH, Score=281, Expect=7e-91]} {Mouse: ENSMUSG00000029063, Nadk, NAD kinase, [RH, Score=276, Expect=4e-89]} {Dmel: FBgn0053156, CG33156, [Score=269, Expect=2e-87]} {Smed: dd_Smed_v6_8020_0_1, dd_Smed_v6_8020_0_1, [Score=186, Expect=3e-55]} {RNA1509_52179, RNA1509_54734} {RNA1310_11933, RNA1509_52179, RNA1509_54734} {RNA1509_52179, RNA1509_54734, RNA815_21893}

Mlig455_030416 {REF} {Length: 2414} {Pfam: ATP-NAD kinase C-terminal domain [PF20143.1, score=116.3]; ATP-NAD kinase N-terminal domain [PF01513.23, score=36.3]} {Human: ENSG00000008130, NADK, NAD kinase, [RH, Score=282, Expect=3e-91]} {Mouse: ENSMUSG00000029063, Nadk, NAD kinase, [RH, Score=276, Expect=5e-90]} {Dmel: FBgn0053156, CG33156, [Score=271, Expect=3e-88]} {Smed: dd_Smed_v6_8020_0_1, dd_Smed_v6_8020_0_1, [Score=186, Expect=2e-55]} {RNA1509_54734} {RNA1310_11933} {RNA815_21893}
16. MligTC455_25937 1835 38.22 Mlig455_009272, Mlig455_016411

Neo: -

Age: -

1.697 0.730 - - 0.967 - -

Mlig455_009272 {REF} {Length: 7436} {TRANSSPLICED} {RNA1509_5983} {RNA1310_1641.1} {RNA815_12846.1}

Mlig455_016411 {REF} {Length: 502} {NoTransDecoderORF} {RNA1310_8260.1} {RNA815_37065}
17. MligTC455_53732 1576 32.83 Mlig455_042222

Neo: -

Age: -

PPP2CA 1.685 - - - - 0.969 0.716 Mlig455_042222 {REF} {Length: 1960} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=119.5]} {Human: ENSG00000113575, PPP2CA, protein phosphatase 2 catalytic subunit alpha, [RH, Score=590, Expect=0.0]; ENSG00000104695, PPP2CB, protein phosphatase 2 catalytic subunit beta, [RH, Score=588, Expect=0.0]} {Mouse: ENSMUSG00000020349, Ppp2ca, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform, [RH, Score=589, Expect=0.0]; ENSMUSG00000009630, Ppp2cb, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform, [RH, Score=588, Expect=0.0]} {Dmel: FBgn0004177, mts, microtubule star, [RH, Score=583, Expect=0.0]} {Celegans: WBGene00002363, let-92, Serine/threonine-protein phosphatase 2A catalytic subunit, [RH, Score=565, Expect=0.0]} {Smed: dd_Smed_v6_1280_0_1, dd_Smed_v6_1280_0_1, [RH, Score=580, Expect=0.0]} {RNA1509_12359, RNA1509_24968, RNA1509_4825} {RNA1310_28799, RNA1509_24968, RNA1509_4825} {RNA1509_24968, RNA1509_4825, RNA815_5316.1}
18. MligTC455_25935 8899 185.4 Mlig455_005516, Mlig455_016410, Mlig455_021701, Mlig455_023346, Mlig455_023821

Neo: -

Age: -

1.675 0.722 - - 0.953 - -

Mlig455_005516 {REF} {Length: 936} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1} {RNA815_12846.1}

Mlig455_016410 {REF} {Length: 1923} {Pfam: FG-GAP repeat [PF01839.25, score=24.8]} {RNA1509_18402, RNA1509_29519} {RNA1310_1040, RNA1509_18402, RNA1509_29519} {RNA1509_18402, RNA1509_29519, RNA815_12503}

Mlig455_021701 {REF} {Length: 932} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1} {RNA815_12846.1}

Mlig455_023346 {REF} {Length: 926} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1} {RNA815_12846.1}

Mlig455_023821 {REF} {Length: 928} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_31799, RNA1509_5983} {RNA1310_12651.1, RNA1509_31799} {RNA1509_31799, RNA815_12846.1}
19. MligTC455_40876 1006 20.96 Mlig455_028183

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.153/0.01519
Region-enriched R3: 1.090/0.00901

ETHE1 0.983 - - - 0.983 - - Mlig455_028183 {REF} {Length: 1716} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=323, Expect=6e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=321, Expect=4e-111]} {Dmel: FBgn0050022, CG30022, [RH, Score=292, Expect=2e-99]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=286, Expect=1e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=318, Expect=2e-110]} {RNA1509_7310} {RNA1310_16001.1} {RNA815_19195}
20. MligTC455_31182 1394 29.04 Mlig455_053151

Neo: -

Age: -

Region-enriched R6: 3.486/0.00001
Region-enriched R5: 3.334/0.00000
Region-enriched R4: 3.071/0.00047
Region-enriched R3: 2.674/0.00253

ANPEP 0.98 - - - 0.980 - - Mlig455_053151 {REF} {Length: 4509} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=262.3]; Peptidase family M1 domain [PF01433.22, score=247.1]; Peptidase M1 N-terminal domain [PF17900.3, score=145.8]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [RH, Score=581, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0039640, CG14516, [RH, Score=538, Expect=9e-176]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [RH, Score=436, Expect=8e-137]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [RH, Score=639, Expect=0.0]} {RNA1509_13872, RNA1509_1573, RNA1509_32492} {RNA1310_1662.1, RNA1509_13872, RNA1509_32492} {RNA1509_13872, RNA1509_32492, RNA815_486.1}
21. MligTC455_46673 2511 52.31 Mlig455_001920

Neo: -

Age: -

WAS 0.966 - - - 0.966 - - Mlig455_001920 {REF} {Length: 3207} {Pfam: WH1 domain [PF00568.25, score=84.7]; P21-Rho-binding domain [PF00786.30, score=27.1]; WH2 motif [PF02205.22, score=19.9]} {Human: ENSG00000015285, WAS, Wiskott-Aldrich syndrome, [RH, Score=138, Expect=7e-35]} {Mouse: ENSMUSG00000029684, Wasl, Wiskott-Aldrich syndrome-like (human), [RH, Score=98.6, Expect=2e-23]} {Dmel: FBgn0024273, WASp, [Score=93.2, Expect=8e-20]} {Smed: dd_Smed_v6_1987_0_1, dd_Smed_v6_1987_0_1, [RH, Score=79.7, Expect=8e-16]} {RNA1509_15317, RNA1509_16868, RNA1509_3515} {RNA1310_20700, RNA1509_15317, RNA1509_16868, RNA1509_3515} {RNA1509_15317, RNA1509_16868, RNA1509_3515, RNA815_12150.1}
22. MligTC455_25934 2552 53.17 Mlig455_009417

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.153/0.02214

0.964 - - - 0.964 - - Mlig455_009417 {REF} {Length: 2629} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_5983} {RNA1310_12651.1, RNA1509_5983} {RNA1509_5983, RNA815_12846.1}
23. MligTC455_49382 1312 27.33 Mlig455_026334

Neo: -

Age: -

Region-enriched R5: 1.174/0.00000

IMMT 0.961 - - - 0.961 - - Mlig455_026334 {REF} {Length: 4063} {Pfam: Mitochondrial inner membrane protein [PF09731.11, score=238.4]} {Human: ENSG00000132305, IMMT, inner membrane mitochondrial protein, [RH, Score=187, Expect=6e-50]} {Mouse: ENSMUSG00000052337, Immt, inner membrane protein, mitochondrial, [RH, Score=188, Expect=2e-50]} {Dmel: FBgn0019960, Mitofilin, [RH, Score=126, Expect=6e-30]} {Celegans: WBGene00020511, immt-1, MICOS complex subunit MIC60-1, [RH, Score=157, Expect=4e-40]} {Smed: dd_Smed_v6_1605_0_1, dd_Smed_v6_1605_0_1, [RH, Score=198, Expect=2e-54]} {RNA1509_29377, RNA1509_40319, RNA1509_49981, RNA1509_6193} {RNA1310_8095, RNA1509_29377, RNA1509_40319, RNA1509_49981, RNA1509_6193} {RNA1509_29377, RNA1509_40319, RNA1509_49981, RNA1509_6193, RNA815_1050.1}
24. MligTC455_19697 1053 21.93 Mlig455_057993

Neo: -

Age: -

ALDH5A1 0.96 - - - 0.960 - - Mlig455_057993 {REF} {Length: 2552} {TRANSSPLICED} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=540.1]} {Human: ENSG00000112294, ALDH5A1, aldehyde dehydrogenase 5 family member A1, [RH, Score=479, Expect=3e-165]} {Mouse: ENSMUSG00000035936, Aldh5a1, aldhehyde dehydrogenase family 5, subfamily A1, [RH, Score=510, Expect=1e-177]} {Dmel: FBgn0039349, Ssadh, Succinic semialdehyde dehydrogenase, [RH, Score=491, Expect=2e-170]} {Celegans: WBGene00000113, alh-7, ALdehyde deHydrogenase, [RH, Score=395, Expect=2e-133]} {Smed: dd_Smed_v6_8292_0_1, dd_Smed_v6_8292_0_1, [RH, Score=441, Expect=5e-151]} {RNA1509_33545, RNA1509_37104, RNA1509_51041, RNA1509_57730} {RNA1310_16721.1, RNA1509_33545, RNA1509_37104, RNA1509_51041} {RNA1509_33545, RNA1509_37104, RNA1509_51041, RNA815_12649.1}
25. MligTC455_11804 40 0.84 Mlig455_049994, Mlig455_050022

Neo: -

Age: Up-Down-Up

0.958 - - - - - 0.958

Mlig455_049994 {REF} {Length: 2541} {TRANSSPLICED} {RNA1310_33428} {RNA815_20155}

Mlig455_050022 {REF} {Length: 1815} {TRANSSPLICED} {RNA1310_33428} {RNA815_20155}
26. MligTC455_23205 87 1.82 Mlig455_056603

Neo: -

Age: Up-Down-Up

LRRK2 0.958 - - - - - 0.958 Mlig455_056603 {REF} {Length: 10346} {Pfam: Protein kinase domain [PF00069.27, score=143.6]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=112.4]; Leucine rich repeat [PF13855.8, score=107.8]; C-terminal of Roc, COR, domain [PF16095.7, score=87.3]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=85.2]; Leucine Rich repeats (2 copies) [PF12799.9, score=66.9]; Ras family [PF00071.24, score=43.4]; Leucine-rich repeat [PF14580.8, score=23.2]} {Human: ENSG00000188906, LRRK2, leucine rich repeat kinase 2, [RH, Score=791, Expect=0.0]} {Mouse: ENSMUSG00000036273, Lrrk2, leucine-rich repeat kinase 2, [RH, Score=785, Expect=0.0]} {Dmel: FBgn0038816, Lrrk, Leucine-rich repeat kinase, [Score=243, Expect=1e-63]} {Celegans: WBGene00003068, lrk-1, Leucine-rich repeat serine/threonine-protein kinase 1, [Score=179, Expect=2e-44]} {Smed: dd_Smed_v6_7343_0_1, dd_Smed_v6_7343_0_1, [RH, Score=669, Expect=0.0]} {RNA1509_6991} {RNA1310_771.1, RNA1509_6991} {RNA1509_6991, RNA815_2219.1}
27. MligTC455_33018 540 11.25 Mlig455_065016

Neo: Int S/G2/M

Age: -

SLX4 0.958 - - - - 0.958 - Mlig455_065016 {REF} {Length: 3818} {TRANSSPLICED} {Human: ENSG00000188827, SLX4, SLX4 structure-specific endonuclease subunit, [RH, Score=53.5, Expect=1e-06]} {Mouse: ENSMUSG00000039738, Slx4, SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae), [Score=50.1, Expect=1e-05]} {RNA1509_23641, RNA1509_23757} {RNA1310_6766, RNA1509_23641, RNA1509_23757} {RNA1509_23641, RNA1509_23757, RNA815_4724}
28. MligTC455_47903 1838 38.28 Mlig455_014075

Neo: Neoblast

Age: -

Region-enriched R5: 1.463/0.00044

0.958 - - - 0.958 - - Mlig455_014075 {REF} {Length: 4449} {RNA1509_13784, RNA1509_17452, RNA1509_23159} {RNA1310_3981.1, RNA1509_13784, RNA1509_17452} {RNA1509_13784, RNA1509_17452, RNA815_7553}
29. MligTC455_29387 709 14.78 Mlig455_005276, Mlig455_008880, Mlig455_024381, Mlig455_027281, Mlig455_028577, Mlig455_033454, Mlig455_035120, Mlig455_037015, Mlig455_044976, Mlig455_061434, Mlig455_066941

Neo: -

Age: -

GRIK1 0.957 - - - 0.957 - -

Mlig455_005276 {REF} {Length: 7197} {Pfam: Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=83.5]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=45.9]} {Human: ENSG00000171189, GRIK1, glutamate ionotropic receptor kainate type subunit 1, [Score=92.4, Expect=5e-20]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=89.7, Expect=4e-19]; ENSG00000163873, GRIK3, glutamate ionotropic receptor kainate type subunit 3, [Score=89.4, Expect=6e-19]} {Mouse: ENSMUSG00000022935, Grik1, glutamate receptor, ionotropic, kainate 1, [Score=92.8, Expect=3e-20]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=89.7, Expect=3e-19]; ENSMUSG00000001985, Grik3, glutamate receptor, ionotropic, kainate 3, [Score=89.4, Expect=4e-19]} {Dmel: FBgn0038837, CG3822, [Score=94.7, Expect=5e-21]} {Celegans: WBGene00001616, glr-5, GLutamate Receptor family (AMPA), [Score=82.0, Expect=6e-17]} {Smed: dd_Smed_v6_20242_0_1, dd_Smed_v6_20242_0_1, [Score=96.7, Expect=6e-22]} {RNA1509_34218} {RNA1310_18727} {RNA815_16176.1}

Mlig455_008880 {REF} {Length: 459} {RNA1509_42537} {RNA1310_72988.1} {RNA815_18625}

Mlig455_024381 {REF} {Length: 729} {NoTransDecoderORF} {RNA1509_42537} {RNA1310_11878, RNA1509_42537} {RNA1509_42537, RNA815_10254}

Mlig455_027281 {REF} {Length: 1410} {RNA1509_21350} {RNA1310_16376} {RNA815_10254}

Mlig455_028577 {REF} {Length: 1281} {RNA1509_21350} {RNA1310_50696} {RNA815_10254}

Mlig455_033454 {REF} {Length: 1450} {RNA1509_21350} {RNA1310_50696} {RNA815_10254}

Mlig455_035120 {REF} {Length: 3087} {NoTransDecoderORF} {RNA1509_38155} {RNA1310_23095} {RNA815_12881}

Mlig455_037015 {REF} {Length: 769} {RNA1509_42537} {RNA1310_16376} {RNA815_10254}

Mlig455_044976 {REF} {Length: 1768} {RNA1509_20190} {RNA1310_11878} {RNA815_10254}

Mlig455_061434 {REF} {Length: 2273} {RNA1509_27760} {RNA1310_23095} {RNA815_16176.1}

Mlig455_066941 {REF} {Length: 401} {NoTransDecoderORF} {RNA1509_44925} {RNA1310_99547, RNA1509_44925} {RNA1509_44925, RNA815_18625}
30. MligTC455_24177 1390 28.95 Mlig455_034202

Neo: -

Age: logFC(26M/2M)=0.443

Region-enriched R5: 1.223/0.01600

PC 0.956 - - - 0.956 - - Mlig455_034202 {REF} {Length: 4942} {TRANSSPLICED} {Pfam: Carbamoyl-phosphate synthase L chain, ATP binding domain [PF02786.19, score=260.2]; Conserved carboxylase domain [PF02436.20, score=226.3]; Biotin carboxylase, N-terminal domain [PF00289.24, score=143.0]; Biotin carboxylase C-terminal domain [PF02785.21, score=107.6]; HMGL-like [PF00682.21, score=90.0]; Biotin-requiring enzyme [PF00364.24, score=55.9]; D-ala D-ala ligase C-terminus [PF07478.15, score=30.6]; Biotin-lipoyl like [PF13533.8, score=23.7]; ATP-grasp domain [PF02222.24, score=23.4]; Na(+)-translocating NADH-quinone reductase subunit A (NQRA) [PF05896.13, score=21.3]; HlyD family secretion protein [PF13437.8, score=20.8]} {Human: ENSG00000173599, PC, pyruvate carboxylase, [RH, Score=1476, Expect=0.0]} {Mouse: ENSMUSG00000024892, Pcx, pyruvate carboxylase, [RH, Score=1466, Expect=0.0]} {Dmel: FBgn0027580, PCB, Pyruvate carboxylase, [RH, Score=1524, Expect=0.0]} {Celegans: WBGene00004258, pyc-1, Pyruvate carboxylase 1, [RH, Score=1470, Expect=0.0]} {Smed: dd_Smed_v6_2393_0_1, dd_Smed_v6_2393_0_1, [RH, Score=1536, Expect=0.0]} {RNA1509_30437, RNA1509_35913, RNA1509_57702, RNA1509_886} {RNA1310_1164.1, RNA1509_30437, RNA1509_35913, RNA1509_57702, RNA1509_886} {RNA1509_30437, RNA1509_35913, RNA1509_57702, RNA1509_886, RNA815_728}
31. MligTC455_43536 47 0.98 Mlig455_066037

Neo: -

Age: Down-Up-Down, logFC(26M/2M)=-0.699

Region-enriched R4: 4.380/0.03075

PAPSS2 0.952 - - - - - 0.952 Mlig455_066037 {REF} {Length: 2522} {TRANSSPLICED} {Pfam: ATP-sulfurylase [PF01747.19, score=146.0]; PUA-like domain [PF14306.8, score=85.1]} {Human: ENSG00000198682, PAPSS2, 3'-phosphoadenosine 5'-phosphosulfate synthase 2, [Score=317, Expect=2e-104]; ENSG00000138801, PAPSS1, 3'-phosphoadenosine 5'-phosphosulfate synthase 1, [Score=314, Expect=5e-103]} {Mouse: ENSMUSG00000024899, Papss2, 3'-phosphoadenosine 5'-phosphosulfate synthase 2, [Score=316, Expect=6e-104]; ENSMUSG00000028032, Papss1, 3'-phosphoadenosine 5'-phosphosulfate synthase 1, [Score=313, Expect=2e-103]} {Dmel: FBgn0020389, Papss, PAPS synthetase, [Score=305, Expect=6e-100]} {Celegans: WBGene00004091, pps-1, 3'-Phosphoadenosine 5'-Phosphosulfate Synthetase, [Score=290, Expect=8e-94]} {Smed: dd_Smed_v6_2536_0_1, dd_Smed_v6_2536_0_1, [Score=308, Expect=2e-101]} {RNA1509_2391} {RNA1310_5399} {RNA815_4222.1}

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