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Results for MligTC455_49086

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_49086 274 5.71 Mlig455_011515

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.627

Region-enriched R3: 2.565/0.00416
Region-enriched R5: 2.441/0.00091
Region-enriched R6: 2.339/0.03988

RAC1 Mlig455_011515 {REF} {Length: 1740} {Pfam: Ras family [PF00071.24, score=159.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=69.7]; ADP-ribosylation factor family [PF00025.23, score=26.0]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=221, Expect=2e-73]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=218, Expect=1e-72]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=217, Expect=4e-72]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=221, Expect=1e-73]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=217, Expect=3e-72]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=217, Expect=3e-72]} {Dmel: FBgn0010333, Rac1, [Score=221, Expect=3e-74]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=226, Expect=5e-76]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=223, Expect=6e-75]} {RNA1509_17203} {RNA1310_15755.1} {RNA815_8276}

Cumulative graph for MligTC455_49086

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -1.953 3.077 0.99844 1.00000
RegionR2 -0.018 3.077 0.81120 1.00000
RegionR3 2.565 3.077 0.00009 0.00416
RegionR4 1.721 3.077 0.01398 0.07836
RegionR5 2.441 3.077 0.00005 0.00091
RegionR6 2.339 3.077 0.00105 0.03988
RegionR7 -0.792 3.077 0.96866 1.00000
RegionR8 -6.305 3.077 0.01514 0.24002

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 -0.002 3.077 0.99601 1.00000
RegenerationR2 -0.134 3.077 0.85239 1.00000
RegenerationR3 0.168 3.077 0.73865 0.96048
RegenerationR4 0.468 3.077 0.39489 0.81013
RegenerationR5 -0.11 3.077 0.81895 0.99404
RegenerationR6 0.015 3.077 0.97595 1.00000
RegenerationBL 1.21 3.077 0.45023 0.81716
RegenerationTP 2.848 3.077 0.17518 0.60881


Genes with expression patterns similar to MligTC455_49086

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_49086 274 5.71 Mlig455_011515

Neo: -

Age: Down-Down-Down, logFC(26M/2M)=-0.627

Region-enriched R3: 2.565/0.00416
Region-enriched R5: 2.441/0.00091
Region-enriched R6: 2.339/0.03988

RAC1 6 1.000 1.000 1.000 1.000 1.000 1.000 Mlig455_011515 {REF} {Length: 1740} {Pfam: Ras family [PF00071.24, score=159.7]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=69.7]; ADP-ribosylation factor family [PF00025.23, score=26.0]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=221, Expect=2e-73]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=218, Expect=1e-72]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=217, Expect=4e-72]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=221, Expect=1e-73]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=217, Expect=3e-72]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=217, Expect=3e-72]} {Dmel: FBgn0010333, Rac1, [Score=221, Expect=3e-74]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=226, Expect=5e-76]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=223, Expect=6e-75]} {RNA1509_17203} {RNA1310_15755.1} {RNA815_8276}
2. MligTC455_49087 353 7.35 Mlig455_049999

Neo: -

Age: logFC(26M/2M)=0.321

Region-enriched R3: 2.015/0.00143
Region-enriched R5: 1.536/0.00732

RAC1 5.534 0.869 0.957 0.979 0.949 0.837 0.943 Mlig455_049999 {REF} {Length: 1762} {Pfam: Ras family [PF00071.24, score=153.1]; Ras of Complex, Roc, domain of DAPkinase [PF08477.15, score=64.3]; ADP-ribosylation factor family [PF00025.23, score=21.0]} {Human: ENSG00000136238, RAC1, Rac family small GTPase 1, [Score=218, Expect=3e-72]; ENSG00000128340, RAC2, Rac family small GTPase 2, [Score=215, Expect=2e-71]; ENSG00000169750, RAC3, Rac family small GTPase 3, [Score=213, Expect=2e-70]} {Mouse: ENSMUSG00000001847, Rac1, Rac family small GTPase 1, [Score=218, Expect=2e-72]; ENSMUSG00000033220, Rac2, Rac family small GTPase 2, [Score=214, Expect=5e-71]; ENSMUSG00000018012, Rac3, Rac family small GTPase 3, [Score=213, Expect=1e-70]} {Dmel: FBgn0010333, Rac1, [Score=218, Expect=6e-73]} {Celegans: WBGene00000424, ced-10, Ras-related protein ced-10, [Score=223, Expect=6e-75]} {Smed: dd_Smed_v6_610_0_1, dd_Smed_v6_610_0_1, [Score=219, Expect=2e-73]} {RNA1509_17203} {RNA1310_15755.1} {RNA815_8276}
3. MligTC455_24145 2194 45.7 Mlig455_041404, Mlig455_041441

Neo: -

Age: -

Region-enriched R4: 1.675/0.00804
Region-enriched R3: 1.664/0.00545
Region-enriched R5: 1.592/0.00276

4.822 0.801 0.749 0.748 0.970 0.708 0.846

Mlig455_041404 {REF} {Length: 1116} {Pfam: WW domain-binding protein 1 [PF11669.10, score=24.2]; SHP2-interacting transmembrane adaptor protein, SIT [PF15330.8, score=19.4]} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}

Mlig455_041441 {REF} {Length: 1161} {Pfam: WW domain-binding protein 1 [PF11669.10, score=25.2]; Transmembrane 52 [PF14979.8, score=19.3]; Proline-rich submaxillary gland androgen-regulated family [PF15621.8, score=19.1]} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}
4. MligTC455_24146 2470 51.46 Mlig455_060904, Mlig455_069370, Mlig455_069388

Neo: -

Age: logFC(26M/2M)=-0.509

Region-enriched R4: 1.799/0.00434
Region-enriched R3: 1.761/0.00220
Region-enriched R5: 1.603/0.00247

3.396 - - 0.779 0.976 0.783 0.858

Mlig455_060904 {REF} {Length: 1171} {Pfam: WW domain-binding protein 1 [PF11669.10, score=23.0]} {RNA1509_12053, RNA1509_23482} {RNA1310_48182, RNA1509_23482} {RNA1509_23482, RNA815_22213}

Mlig455_069370 {REF} {Length: 1132} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}

Mlig455_069388 {REF} {Length: 1155} {Pfam: WW domain-binding protein 1 [PF11669.10, score=23.6]} {RNA1509_12053} {RNA1310_48182} {RNA815_22213}
5. MligTC455_18366 547 11.39 Mlig455_026325

Neo: -

Age: Down-Down-Up

Region-enriched R4: 3.044/0.02719
Region-enriched R3: 2.953/0.02551

IFI30 2.58 - - - 0.843 0.967 0.770 Mlig455_026325 {REF} {Length: 1133} {Pfam: Gamma interferon inducible lysosomal thiol reductase (GILT) [PF03227.18, score=101.0]} {Human: ENSG00000216490, IFI30, IFI30, lysosomal thiol reductase, [RH, Score=143, Expect=1e-41]} {Mouse: ENSMUSG00000110777, Ifi30, interferon gamma inducible protein 30, [RH, Score=118, Expect=4e-32]} {Dmel: FBgn0038149, GILT1, Gamma-interferon-inducible lysosomal thiol reductase 1, [Score=95.5, Expect=1e-23]} {Celegans: WBGene00009514, F37H8.5, GILT-like protein F37H8.5, [Score=100, Expect=3e-25]} {Smed: dd_Smed_v6_2024_0_1, dd_Smed_v6_2024_0_1, [Score=104, Expect=8e-28]} {RNA1509_51694} {RNA1310_32351.1} {RNA815_17592}
6. MligTC455_34207 12055 251.14 Mlig455_035831

Neo: -

Age: logFC(26M/2M)=0.753

Region-enriched R3: 1.887/0.00004

Regeneration-upregulated TP: 2.075

Regeneration-enriched TP: 2.075

AC099489.1 2.577 - 0.767 - 0.967 0.843 - Mlig455_035831 {REF} {Length: 10908} {Pfam: Lipoprotein amino terminal region [PF01347.24, score=126.2]; Domain of unknown function (DUF1943) [PF09172.13, score=95.1]; von Willebrand factor type D domain [PF00094.27, score=31.2]} {Human: ENSG00000188897, AC099489.1, vitellogenin, [Score=65.5, Expect=2e-09]} {Mouse: ENSMUSG00000020609, Apob, apolipoprotein B, [Score=57.8, Expect=3e-07]} {Dmel: FBgn0087002, apolpp, apolipophorin, [Score=77.0, Expect=4e-13]} {Smed: dd_Smed_v6_636_0_1, dd_Smed_v6_636_0_1, [Score=145, Expect=4e-34]} {RNA1509_19, RNA1509_35407} {RNA1310_78, RNA1509_35407} {RNA1509_35407, RNA815_36.1}
7. MligTC455_40877 940 19.59 Mlig455_028254

Neo: -

Age: -

Region-enriched R4: 1.189/0.01108
Region-enriched R3: 1.015/0.01751

ETHE1 2.55 0.741 - - 0.972 - 0.837 Mlig455_028254 {REF} {Length: 1819} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=325, Expect=1e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=322, Expect=1e-111]} {Dmel: FBgn0050022, CG30022, [Score=290, Expect=1e-98]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=285, Expect=3e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=317, Expect=9e-110]} {RNA1509_7310} {RNA1310_16001.1, RNA1509_7310} {RNA1509_7310, RNA815_19195}
8. MligTC455_45385 1307 27.23 Mlig455_045374

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-0.488

Region-enriched R3: 1.834/0.00162
Region-enriched R5: 1.310/0.01840

PPP1R3C 2.542 - 0.751 - - 0.836 0.955 Mlig455_045374 {REF} {Length: 1627} {Pfam: Carbohydrate/starch-binding module (family 21) [PF03370.15, score=36.6]; Starch/carbohydrate-binding module (family 53) [PF16760.7, score=33.7]} {Human: ENSG00000119938, PPP1R3C, protein phosphatase 1 regulatory subunit 3C, [Score=53.1, Expect=2e-07]} {RNA1509_11258, RNA1509_19500, RNA1509_40029} {RNA1310_23008, RNA1509_11258, RNA1509_19500, RNA1509_40029} {RNA1509_11258, RNA1509_19500, RNA1509_40029, RNA815_7814}
9. MligTC455_24869 3528 73.49 Mlig455_039885, Mlig455_039903, Mlig455_039939

Neo: -

Age: Up-Down-Down

Region-enriched R3: 2.614/0.00079

MRC1 2.538 - - 0.779 0.957 - 0.802

Mlig455_039885 {REF} {Length: 6516} {Pfam: Lectin C-type domain [PF00059.23, score=685.5]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=75.5]; Extracellular link domain [PF00193.19, score=22.7]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [RH, Score=492, Expect=6e-146]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [RH, Score=494, Expect=1e-146]} {Dmel: FBgn0040102, lectin-24Db, [RH, Score=72.0, Expect=1e-12]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [RH, Score=95.1, Expect=1e-20]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [RH, Score=228, Expect=4e-60]} {RNA1509_240} {RNA1310_205.1} {RNA815_95}

Mlig455_039903 {REF} {Length: 6532} {Pfam: Lectin C-type domain [PF00059.23, score=559.4]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=65.7]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=365, Expect=9e-104]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=348, Expect=5e-98]} {Dmel: FBgn0040102, lectin-24Db, [RH, Score=71.6, Expect=1e-12]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [RH, Score=94.0, Expect=2e-20]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=202, Expect=2e-52]} {RNA1509_23542, RNA1509_240, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472} {RNA1310_205.1, RNA1509_23542, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472} {RNA1509_23542, RNA1509_26945, RNA1509_4040, RNA1509_58519, RNA1509_59472, RNA815_95}

Mlig455_039939 {REF} {Length: 6496} {Pfam: Lectin C-type domain [PF00059.23, score=267.5]; UL45 protein, carbohydrate-binding C-type lectin-like [PF05473.14, score=42.5]} {Human: ENSG00000260314, MRC1, mannose receptor C-type 1, [Score=180, Expect=2e-46]} {Mouse: ENSMUSG00000026712, Mrc1, mannose receptor, C type 1, [Score=172, Expect=6e-44]} {Dmel: FBgn0035199, tfc, triforce, [Score=60.8, Expect=2e-10]} {Celegans: WBGene00015050, clec-51, C-type LECtin, [Score=89.0, Expect=4e-19]} {Smed: dd_Smed_v6_3193_0_2, dd_Smed_v6_3193_0_2, [Score=99.0, Expect=4e-21]} {RNA1509_240} {RNA1310_205.1} {RNA815_95}
10. MligTC455_27982 2224 46.32 Mlig455_014695, Mlig455_014738

Neo: -

Age: -

Region-enriched R3: 1.878/0.03979

SLC9A3R2 2.497 - 0.722 - 0.954 - 0.821

Mlig455_014695 {REF} {Length: 1932} {Pfam: PDZ domain [PF00595.26, score=39.6]; PDZ domain [PF17820.3, score=26.5]; PDZ domain [PF13180.8, score=25.5]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=94.7, Expect=8e-22]} {Mouse: ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=96.7, Expect=2e-22]; ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=93.6, Expect=1e-21]} {Dmel: FBgn0010620, CG10939, [Score=87.0, Expect=1e-19]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=89.7, Expect=5e-20]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=107, Expect=2e-28]} {RNA1509_5277, RNA1509_8845} {RNA1310_17362, RNA1509_5277, RNA1509_8845} {RNA1509_5277, RNA1509_8845, RNA815_22754.1}

Mlig455_014738 {REF} {Length: 1929} {Pfam: PDZ domain [PF00595.26, score=41.4]; PDZ domain [PF17820.3, score=26.4]; PDZ domain [PF13180.8, score=23.8]} {Human: ENSG00000065054, SLC9A3R2, SLC9A3 regulator 2, [RH, Score=97.4, Expect=7e-23]} {Mouse: ENSMUSG00000002504, Slc9a3r2, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2, [RH, Score=96.7, Expect=1e-22]; ENSMUSG00000020733, Slc9a3r1, solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1, [RH, Score=95.9, Expect=3e-22]} {Dmel: FBgn0010620, CG10939, [Score=89.7, Expect=2e-20]} {Celegans: WBGene00006438, nrfl-1, NHERF (Mammalian Na/H Exchange Regulatory Factor) Like, [Score=92.4, Expect=5e-21]} {Smed: dd_Smed_v6_3039_0_1, dd_Smed_v6_3039_0_1, [Score=110, Expect=3e-29]} {RNA1509_39084} {RNA1310_17362, RNA1509_39084} {RNA1509_39084, RNA815_22754.1}
11. MligTC455_43369 2802 58.37 Mlig455_067767

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.465

ACHE 2.48 - 0.728 - 0.952 - 0.800 Mlig455_067767 {REF} {Length: 11472} {Pfam: Carboxylesterase family [PF00135.30, score=972.4]; alpha/beta hydrolase fold [PF07859.15, score=53.6]} {Human: ENSG00000087085, ACHE, acetylcholinesterase (Cartwright blood group), [Score=222, Expect=1e-60]} {Mouse: ENSMUSG00000023328, Ache, acetylcholinesterase, [Score=215, Expect=1e-58]} {Dmel: FBgn0027584, CG4757, [RH, Score=181, Expect=7e-48]} {Celegans: WBGene00000035, ace-1, Acetylcholinesterase 1, [Score=189, Expect=5e-50]} {Smed: dd_Smed_v6_10334_0_1, dd_Smed_v6_10334_0_1, [Score=191, Expect=7e-51]} {RNA1509_27104, RNA1509_6008, RNA1509_82} {RNA1310_83.1, RNA1509_27104, RNA1509_6008, RNA1509_82} {RNA1509_27104, RNA1509_6008, RNA1509_82, RNA815_40.1}
12. MligTC455_11294 430 8.95 Mlig455_068327

Neo: -

Age: -

2.44 - - - 0.957 0.722 0.761 Mlig455_068327 {REF} {Length: 1267} {Pfam: Gp5 C-terminal repeat (3 copies) [PF06715.14, score=21.5]} {RNA1509_10965} {RNA1310_87215.1} {RNA815_44952}
13. MligTC455_40148 859 17.9 Mlig455_017851, Mlig455_047871

Neo: -

Age: -

Region-enriched R4: 2.301/0.00625

1.833 - - - 0.951 - 0.882

Mlig455_017851 {REF} {Length: 2678} {RNA1509_11917, RNA1509_28007, RNA1509_35856} {RNA1310_13722, RNA1509_11917, RNA1509_28007, RNA1509_35856} {RNA1509_11917, RNA1509_28007, RNA1509_35856, RNA815_5229}

Mlig455_047871 {REF} {Length: 1990} {RNA1509_11917} {RNA1310_13722} {RNA815_5229}
14. MligTC455_48968 2833 59.01 Mlig455_068344

Neo: -

Age: -

1.828 - - - 0.952 - 0.876 Mlig455_068344 {REF} {Length: 680} {TRANSSPLICED} {Pfam: Type III secretion system lipoprotein chaperone (YscW) [PF09619.12, score=24.2]} {RNA1509_52356} {RNA1310_19739.1} {RNA815_20380}
15. MligTC455_34295 1251 26.06 Mlig455_039417

Neo: -

Age: Down-Down-Up, logFC(26M/2M)=-1.176

Region-enriched R3: 2.357/0.00048
Region-enriched R4: 1.872/0.01857

1.818 - - - - 0.955 0.863 Mlig455_039417 {REF} {Length: 666} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1310_54443, RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827} {RNA1509_26409, RNA1509_26731, RNA1509_44065, RNA1509_51827, RNA815_29054}
16. MligTC455_43763 1548 32.26 Mlig455_009134

Neo: -

Age: -

ETFDH 1.801 - - - 0.970 - 0.831 Mlig455_009134 {REF} {Length: 3198} {TRANSSPLICED} {Pfam: Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S [PF05187.15, score=158.2]; FAD dependent oxidoreductase [PF01266.26, score=34.3]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=32.5]; FAD binding domain [PF00890.26, score=32.1]; Thi4 family [PF01946.19, score=31.3]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=27.3]; FAD-NAD(P)-binding [PF13454.8, score=23.5]; FAD binding domain [PF01494.21, score=19.2]; Alanine dehydrogenase/PNT, C-terminal domain [PF01262.23, score=18.7]; HI0933-like protein [PF03486.16, score=18.2]} {Human: ENSG00000171503, ETFDH, electron transfer flavoprotein dehydrogenase, [RH, Score=814, Expect=0.0]} {Mouse: ENSMUSG00000027809, Etfdh, electron transferring flavoprotein, dehydrogenase, [RH, Score=829, Expect=0.0]} {Dmel: FBgn0033465, Etf-QO, Electron transfer flavoprotein-ubiquinone oxidoreductase, [RH, Score=753, Expect=0.0]} {Celegans: WBGene00002855, let-721, Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, [RH, Score=745, Expect=0.0]} {Smed: dd_Smed_v6_3785_0_1, dd_Smed_v6_3785_0_1, [RH, Score=872, Expect=0.0]} {RNA1509_2025, RNA1509_6739} {RNA1310_8787, RNA1509_2025, RNA1509_6739} {RNA1509_2025, RNA1509_6739, RNA815_3614}
17. MligTC455_33006 2208 45.99 Mlig455_063158

Neo: -

Age: Down-Up-Up

Region-enriched R4: 2.219/0.00001
Region-enriched R3: 1.514/0.00240

1.761 - - - - 0.965 0.796 Mlig455_063158 {REF} {Length: 2059} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=27.0]} {RNA1509_4524} {RNA1310_31808} {RNA815_13487}
18. MligTC455_35286 429 8.95 Mlig455_025517

Neo: -

Age: -

PDE5A 1.754 - - - - 0.950 0.804 Mlig455_025517 {REF} {Length: 3725} {Pfam: 3'5'-cyclic nucleotide phosphodiesterase [PF00233.21, score=232.7]; GAF domain [PF01590.28, score=104.2]; GAF domain [PF13185.8, score=56.8]; GAF domain [PF13492.8, score=27.7]} {Human: ENSG00000138735, PDE5A, phosphodiesterase 5A, [RH, Score=627, Expect=0.0]; ENSG00000128655, PDE11A, phosphodiesterase 11A, [RH, Score=610, Expect=0.0]} {Mouse: ENSMUSG00000053965, Pde5a, phosphodiesterase 5A, cGMP-specific, [RH, Score=623, Expect=0.0]; ENSMUSG00000075270, Pde11a, phosphodiesterase 11A, [RH, Score=619, Expect=0.0]} {Dmel: FBgn0085370, Pde11, Phosphodiesterase 11, [RH, Score=639, Expect=0.0]} {Celegans: WBGene00016328, pde-5, Probable 3',5'-cyclic phosphodiesterase pde-5, [Score=307, Expect=6e-92]} {Smed: dd_Smed_v6_8595_0_4, dd_Smed_v6_8595_0_4, [RH, Score=680, Expect=0.0]} {RNA1509_11890} {RNA1310_3423.1, RNA1509_11890} {RNA1509_11890, RNA815_991}
19. MligTC455_18869 1346 28.04 Mlig455_067491

Neo: -

Age: -

Region-enriched R3: 1.933/0.00397
Region-enriched R4: 1.775/0.01938
Region-enriched R5: 1.440/0.02287

1.742 - - - - 0.956 0.786 Mlig455_067491 {REF} {Length: 2320} {Pfam: NAD dependent epimerase/dehydratase family [PF01370.23, score=72.5]; GDP-mannose 4,6 dehydratase [PF16363.7, score=51.3]; 3-beta hydroxysteroid dehydrogenase/isomerase family [PF01073.21, score=46.4]; Male sterility protein [PF07993.14, score=42.2]; NAD(P)H-binding [PF13460.8, score=39.3]; Polysaccharide biosynthesis protein [PF02719.17, score=30.0]; KR domain [PF08659.12, score=29.5]; NmrA-like family [PF05368.15, score=28.0]; short chain dehydrogenase [PF00106.27, score=19.3]} {Celegans: WBGene00017429, F13D11.4, [RH, Score=213, Expect=4e-66]} {RNA1509_20033, RNA1509_5037} {RNA1310_19379, RNA1509_20033, RNA1509_5037} {RNA1509_20033, RNA1509_5037, RNA815_6182.1}
20. MligTC455_18598 756 15.74 Mlig455_063584

Neo: -

Age: -

Region-enriched R4: 1.920/0.00186
Region-enriched R5: 1.402/0.00352

AGPS 1.732 - - - 0.955 - 0.777 Mlig455_063584 {REF} {Length: 3203} {TRANSSPLICED} {Pfam: FAD binding domain [PF01565.25, score=117.2]; FAD linked oxidases, C-terminal domain [PF02913.21, score=113.7]} {Human: ENSG00000018510, AGPS, alkylglycerone phosphate synthase, [RH, Score=692, Expect=0.0]} {Mouse: ENSMUSG00000042410, Agps, alkylglycerone phosphate synthase, [Score=701, Expect=0.0]} {Dmel: FBgn0033983, ADPS, Alkyldihydroxyacetonephosphate synthase, [Score=586, Expect=0.0]} {Celegans: WBGene00000081, ads-1, Alkyldihydroxyacetonephosphate synthase, [Score=594, Expect=0.0]} {Smed: dd_Smed_v6_2115_0_1, dd_Smed_v6_2115_0_1, [Score=632, Expect=0.0]} {RNA1509_6531} {RNA1310_6470.2} {RNA815_2634}
21. MligTC455_18868 1328 27.67 Mlig455_067483

Neo: -

Age: -

Region-enriched R3: 1.928/0.00492
Region-enriched R4: 1.837/0.01691
Region-enriched R5: 1.462/0.02245

1.728 - - - - 0.953 0.775 Mlig455_067483 {REF} {Length: 405} {RNA1509_5037} {RNA1310_19379} {RNA815_6182.1}
22. MligTC455_43059 434 9.03 Mlig455_008726, Mlig455_063596

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=1.270

Region-enriched R4: 2.302/0.00117
Region-enriched R3: 1.385/0.03871
Region-enriched R5: 1.313/0.01489

GGT1 1.727 - 0.752 - - - 0.975

Mlig455_008726 {REF} {Length: 3111} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=536.2]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=414, Expect=2e-137]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [RH, Score=405, Expect=3e-134]} {Dmel: FBgn0025837, CG17636, [RH, Score=344, Expect=8e-111]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=387, Expect=2e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=436, Expect=4e-146]} {RNA1509_59755} {RNA1310_21899} {RNA815_2837}

Mlig455_063596 {REF} {Length: 2850} {Pfam: Gamma-glutamyltranspeptidase [PF01019.23, score=536.2]} {Human: ENSG00000100031, GGT1, gamma-glutamyltransferase 1, [RH, Score=414, Expect=2e-137]} {Mouse: ENSMUSG00000006345, Ggt1, gamma-glutamyltransferase 1, [RH, Score=405, Expect=3e-134]} {Dmel: FBgn0025837, CG17636, [RH, Score=344, Expect=8e-111]} {Celegans: WBGene00016906, C53D5.5, [RH, Score=387, Expect=2e-126]} {Smed: dd_Smed_v6_4591_0_1, dd_Smed_v6_4591_0_1, [RH, Score=436, Expect=4e-146]} {RNA1509_10553, RNA1509_41651} {RNA1310_21899, RNA1509_41651} {RNA1509_41651, RNA815_24200}
23. MligTC455_15188 521 10.85 Mlig455_063143

Neo: -

Age: logFC(26M/2M)=-0.240

Region-enriched R7: 2.723/0.00019

FOXRED2 1.716 - - - - 0.960 0.756 Mlig455_063143 {REF} {Length: 2952} {Pfam: Pyridine nucleotide-disulphide oxidoreductase [PF13738.8, score=163.4]; Pyridine nucleotide-disulphide oxidoreductase [PF07992.16, score=54.9]; L-lysine 6-monooxygenase (NADPH-requiring) [PF13434.8, score=34.6]; NAD(P)-binding Rossmann-like domain [PF13450.8, score=27.3]; FAD dependent oxidoreductase [PF01266.26, score=25.9]; HI0933-like protein [PF03486.16, score=24.8]; Pyridine nucleotide-disulphide oxidoreductase [PF00070.29, score=22.9]; FAD binding domain [PF01494.21, score=20.3]; Flavin-binding monooxygenase-like [PF00743.21, score=19.2]} {Human: ENSG00000100350, FOXRED2, FAD dependent oxidoreductase domain containing 2, [RH, Score=497, Expect=8e-168]} {Mouse: ENSMUSG00000016552, Foxred2, FAD-dependent oxidoreductase domain containing 2, [RH, Score=481, Expect=6e-162]} {Smed: dd_Smed_v6_12138_0_1, dd_Smed_v6_12138_0_1, [RH, Score=468, Expect=5e-158]} {RNA1509_11180, RNA1509_38655, RNA1509_53383} {RNA1310_8010, RNA1509_11180, RNA1509_38655, RNA1509_53383} {RNA1509_11180, RNA1509_38655, RNA1509_53383, RNA815_3364.1}
24. MligTC455_40876 1006 20.96 Mlig455_028183

Neo: -

Age: Down-Up-Down

Region-enriched R4: 1.153/0.01519
Region-enriched R3: 1.090/0.00901

ETHE1 1.697 0.729 - - 0.968 - - Mlig455_028183 {REF} {Length: 1716} {TRANSSPLICED} {Pfam: Metallo-beta-lactamase superfamily [PF00753.29, score=45.0]} {Human: ENSG00000105755, ETHE1, ETHE1, persulfide dioxygenase, [RH, Score=323, Expect=6e-112]} {Mouse: ENSMUSG00000064254, Ethe1, ethylmalonic encephalopathy 1, [RH, Score=321, Expect=4e-111]} {Dmel: FBgn0050022, CG30022, [RH, Score=292, Expect=2e-99]} {Celegans: WBGene00007886, ethe-1, ETHE1 (Human ETHylmalonic Encephalopathy) homolog, [RH, Score=286, Expect=1e-97]} {Smed: dd_Smed_v6_944_0_1, dd_Smed_v6_944_0_1, [RH, Score=318, Expect=2e-110]} {RNA1509_7310} {RNA1310_16001.1} {RNA815_19195}
25. MligTC455_04268 205 4.26 Mlig455_020034

Neo: -

Age: -

Region-enriched R5: 2.401/0.04505

1.686 - - - - 0.733 0.953 Mlig455_020034 {REF} {Length: 2636} {Pfam: Tetraspanin family [PF00335.22, score=70.2]; Zinc finger, C3HC4 type (RING finger) [PF13920.8, score=28.8]; Inhibitor of Apoptosis domain [PF00653.23, score=20.2]} {Smed: dd_Smed_v6_546_0_1, dd_Smed_v6_546_0_1, [Score=47.4, Expect=9e-06]} {RNA1509_7464} {RNA1310_34864} {RNA815_16518}
26. MligTC455_29311 38 0.79 Mlig455_036659

Neo: -

Age: -

Region-enriched R4: 5.181/0.01948
Region-enriched R5: 4.507/0.01647

1.686 - - 0.972 - - 0.714 Mlig455_036659 {REF} {Length: 559} {TRANSSPLICED} {RNA1310_66594.1} {RNA815_40011}
27. MligTC455_22353 204 4.24 Mlig455_031527

Neo: -

Age: Down-Up-Down

EIF2B3 1.662 - - 0.952 - - 0.710 Mlig455_031527 {REF} {Length: 2418} {TRANSSPLICED} {Pfam: MobA-like NTP transferase domain [PF12804.9, score=34.7]; Nucleotidyl transferase [PF00483.25, score=31.8]; Domain of unknown function (DUF4954) [PF16314.7, score=22.9]; Bacterial transferase hexapeptide (six repeats) [PF00132.26, score=21.0]} {Human: ENSG00000070785, EIF2B3, eukaryotic translation initiation factor 2B subunit gamma, [RH, Score=125, Expect=1e-30]} {Mouse: ENSMUSG00000028683, Eif2b3, eukaryotic translation initiation factor 2B, subunit 3, [RH, Score=136, Expect=6e-35]} {Dmel: FBgn0034029, eIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma, [RH, Score=143, Expect=2e-37]} {Celegans: WBGene00004090, eif-2Bgamma, Probable translation initiation factor eIF-2B subunit gamma, [RH, Score=71.6, Expect=3e-13]} {RNA1509_30817, RNA1509_53347, RNA1509_58887} {RNA1310_17674, RNA1509_53347, RNA1509_58887} {RNA1509_53347, RNA1509_58887, RNA815_11116}
28. MligTC455_39806 2410 50.2 Mlig455_035356, Mlig455_035396

Neo: -

Age: logFC(26M/2M)=0.475

0.971 - - - 0.971 - -

Mlig455_035356 {REF} {Length: 720} {RNA1509_11746, RNA1509_20417, RNA1509_28901, RNA1509_41712} {RNA1310_32492.1, RNA1509_11746, RNA1509_20417, RNA1509_28901, RNA1509_41712} {RNA1509_11746, RNA1509_20417, RNA1509_28901, RNA1509_41712, RNA815_24107.1}

Mlig455_035396 {REF} {Length: 1846} {RNA1509_41712} {RNA1310_32492.2} {RNA815_24107.1}
29. MligTC455_19571 263 5.49 Mlig455_003635

Neo: -

Age: -

CRYZ 0.965 - - - - - 0.965 Mlig455_003635 {REF} {Length: 1497} {TRANSSPLICED} {Pfam: Zinc-binding dehydrogenase [PF00107.28, score=65.2]; Zinc-binding dehydrogenase [PF13602.8, score=47.1]; Alcohol dehydrogenase GroES-like domain [PF08240.14, score=35.1]} {Human: ENSG00000116791, CRYZ, crystallin zeta, [RH, Score=281, Expect=4e-93]} {Mouse: ENSMUSG00000028199, Cryz, crystallin, zeta, [RH, Score=286, Expect=4e-95]} {Dmel: FBgn0033883, CG16935, [RH, Score=70.9, Expect=2e-13]} {Celegans: WBGene00009554, F39B2.3, [RH, Score=223, Expect=1e-70]} {Smed: dd_Smed_v6_2717_0_1, dd_Smed_v6_2717_0_1, [RH, Score=254, Expect=5e-83]} {RNA1509_24531} {RNA1310_28792.1} {RNA815_12373.1}
30. MligTC455_53411 310 6.47 Mlig455_011608

Neo: -

Age: logFC(26M/2M)=-0.670

Region-enriched R4: 3.076/0.01313
Region-enriched R5: 2.796/0.00625

0.965 - - - - - 0.965 Mlig455_011608 {REF} {Length: 2954} {Smed: dd_Smed_v6_862_0_1, dd_Smed_v6_862_0_1, [RH, Score=48.9, Expect=2e-07]} {RNA1310_28494.1} {RNA815_17411}
31. MligTC455_42665 67 1.39 Mlig455_043259

Neo: -

Age: -

0.962 - - 0.962 - - - Mlig455_043259 {REF} {Length: 3666} {TRANSSPLICED} {RNA1509_19907} {RNA1310_11028} {RNA815_16751}
32. MligTC455_49351 493 10.28 Mlig455_025393

Neo: Int S/G2/M

Age: Down-Up-Up

GGCT 0.96 - - 0.960 - - - Mlig455_025393 {REF} {Length: 1363} {TRANSSPLICED} {Pfam: AIG2-like family [PF13772.8, score=86.6]; Gamma-glutamyl cyclotransferase, AIG2-like [PF06094.14, score=26.7]} {Human: ENSG00000006625, GGCT, gamma-glutamylcyclotransferase, [RH, Score=133, Expect=7e-39]} {Mouse: ENSMUSG00000002797, Ggct, gamma-glutamyl cyclotransferase, [RH, Score=125, Expect=5e-36]} {Dmel: FBgn0052196, CG32196, [RH, Score=109, Expect=9e-30]} {Celegans: WBGene00016629, C44B7.7, [RH, Score=118, Expect=2e-33]} {Smed: dd_Smed_v6_6495_0_2, dd_Smed_v6_6495_0_2, [RH, Score=149, Expect=3e-45]} {RNA1509_26975, RNA1509_42530} {RNA1310_25089, RNA1509_26975, RNA1509_42530} {RNA1509_26975, RNA1509_42530, RNA815_20035}
33. MligTC455_23055 2998 62.46 Mlig455_004780, Mlig455_004864

Neo: -

Age: Down-Up-Up

MRPS33 0.958 - - - 0.958 - -

Mlig455_004780 {REF} {Length: 461} {TRANSSPLICED} {Pfam: Mitochondrial ribosomal subunit S27 [PF08293.13, score=46.7]} {Human: ENSG00000090263, MRPS33, mitochondrial ribosomal protein S33, [RH, Score=67.4, Expect=2e-15]} {Mouse: ENSMUSG00000029918, Mrps33, mitochondrial ribosomal protein S33, [RH, Score=67.8, Expect=9e-16]} {Dmel: FBgn0038426, mRpS33, mitochondrial ribosomal protein S33, [RH, Score=75.9, Expect=6e-19]} {Celegans: WBGene00009013, mrps-33, Mitochondrial Ribosomal Protein, Small, [RH, Score=48.9, Expect=2e-08]} {Smed: dd_Smed_v6_3607_0_1, dd_Smed_v6_3607_0_1, [RH, Score=79.7, Expect=1e-20]} {RNA1509_50368, RNA1509_8255} {RNA1310_76540, RNA1509_50368, RNA1509_8255} {RNA1509_50368, RNA1509_8255, RNA815_39196}

Mlig455_004864 {REF} {Length: 461} {TRANSSPLICED} {Pfam: Mitochondrial ribosomal subunit S27 [PF08293.13, score=46.7]} {Human: ENSG00000090263, MRPS33, mitochondrial ribosomal protein S33, [RH, Score=67.4, Expect=2e-15]} {Mouse: ENSMUSG00000029918, Mrps33, mitochondrial ribosomal protein S33, [RH, Score=67.8, Expect=9e-16]} {Dmel: FBgn0038426, mRpS33, mitochondrial ribosomal protein S33, [RH, Score=75.9, Expect=6e-19]} {Celegans: WBGene00009013, mrps-33, Mitochondrial Ribosomal Protein, Small, [RH, Score=48.9, Expect=2e-08]} {Smed: dd_Smed_v6_3607_0_1, dd_Smed_v6_3607_0_1, [RH, Score=79.7, Expect=1e-20]} {RNA1509_50368} {RNA1310_76540} {RNA815_39196}
34. MligTC455_31182 1394 29.04 Mlig455_053151

Neo: -

Age: -

Region-enriched R6: 3.486/0.00001
Region-enriched R5: 3.334/0.00000
Region-enriched R4: 3.071/0.00047
Region-enriched R3: 2.674/0.00253

ANPEP 0.955 - - - 0.955 - - Mlig455_053151 {REF} {Length: 4509} {Pfam: ERAP1-like C-terminal domain [PF11838.10, score=262.3]; Peptidase family M1 domain [PF01433.22, score=247.1]; Peptidase M1 N-terminal domain [PF17900.3, score=145.8]} {Human: ENSG00000166825, ANPEP, alanyl aminopeptidase, membrane, [RH, Score=581, Expect=0.0]} {Mouse: ENSMUSG00000039062, Anpep, alanyl (membrane) aminopeptidase, [RH, Score=574, Expect=0.0]} {Dmel: FBgn0039640, CG14516, [RH, Score=538, Expect=9e-176]} {Celegans: WBGene00011587, T07F10.1, Aminopeptidase, [RH, Score=436, Expect=8e-137]} {Smed: dd_Smed_v6_6470_0_1, dd_Smed_v6_6470_0_1, [RH, Score=639, Expect=0.0]} {RNA1509_13872, RNA1509_1573, RNA1509_32492} {RNA1310_1662.1, RNA1509_13872, RNA1509_32492} {RNA1509_13872, RNA1509_32492, RNA815_486.1}
35. MligTC455_44082 1524 31.75 Mlig455_000547

Neo: -

Age: logFC(26M/2M)=-0.310

Region-enriched R4: 1.014/0.01171

SLC30A1 0.955 - - - 0.955 - - Mlig455_000547 {REF} {Length: 4129} {TRANSSPLICED} {Pfam: Cation efflux family [PF01545.23, score=161.1]} {Human: ENSG00000170385, SLC30A1, solute carrier family 30 member 1, [Score=235, Expect=2e-70]} {Mouse: ENSMUSG00000037434, Slc30a1, solute carrier family 30 (zinc transporter), member 1, [RH, Score=235, Expect=1e-70]; ENSMUSG00000110850, Slc30a1, solute carrier family 30 (zinc transporter), member 1, [RH, Score=235, Expect=1e-70]} {Dmel: FBgn0035432, ZnT63C, Zinc transporter 63C, [Score=146, Expect=3e-38]} {Celegans: WBGene00000393, cdf-1, Cation diffusion facilitator family protein 1, [Score=92.0, Expect=1e-19]} {Smed: dd_Smed_v6_3042_0_1, dd_Smed_v6_3042_0_1, [Score=301, Expect=4e-97]} {RNA1509_16572, RNA1509_18374, RNA1509_32458, RNA1509_43388, RNA1509_48373, RNA1509_48567, RNA1509_48958, RNA1509_51367} {RNA1310_16932, RNA1509_16572, RNA1509_18374, RNA1509_32458, RNA1509_43388, RNA1509_48373, RNA1509_48567, RNA1509_48958, RNA1509_51367} {RNA1509_16572, RNA1509_18374, RNA1509_32458, RNA1509_43388, RNA1509_48373, RNA1509_48567, RNA1509_48958, RNA1509_51367, RNA815_13815}
36. MligTC455_42764 351 7.31 Mlig455_031291, Mlig455_031338

Neo: -

Age: -

Region-enriched R4: 2.254/0.02916
Region-enriched R5: 2.042/0.00169

ALDH16A1 0.954 - - 0.954 - - -

Mlig455_031291 {REF} {Length: 2722} {TRANSSPLICED} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=65.1]} {Human: ENSG00000161618, ALDH16A1, aldehyde dehydrogenase 16 family member A1, [Score=54.3, Expect=6e-07]} {RNA1509_14483} {RNA1310_10423.1} {RNA815_28466}

Mlig455_031338 {REF} {Length: 2766} {Pfam: Aldehyde dehydrogenase family [PF00171.24, score=66.0]} {RNA1509_14483, RNA1509_19770} {RNA1310_10423.1, RNA1509_19770} {RNA1509_19770, RNA815_28466}
37. MligTC455_50832 2941 61.27 Mlig455_019665, Mlig455_048084

Neo: -

Age: -

HMBS 0.952 - - - 0.952 - -

Mlig455_019665 {REF} {Length: 2165} {TRANSSPLICED} {Pfam: Porphobilinogen deaminase, dipyromethane cofactor binding domain [PF01379.22, score=239.2]; Porphobilinogen deaminase, C-terminal domain [PF03900.17, score=51.1]} {Human: ENSG00000256269, HMBS, hydroxymethylbilane synthase, [RH, Score=246, Expect=9e-78]; ENSG00000281702, HMBS, hydroxymethylbilane synthase, [RH, Score=246, Expect=9e-78]} {Mouse: ENSMUSG00000032126, Hmbs, hydroxymethylbilane synthase, [RH, Score=243, Expect=2e-76]} {Dmel: FBgn0010786, l(3)02640, lethal (3) 02640, [RH, Score=231, Expect=6e-69]} {Smed: dd_Smed_v6_1346_0_1, dd_Smed_v6_1346_0_1, [RH, Score=252, Expect=1e-79]} {RNA1509_54384} {RNA1310_2114.1, RNA1509_54384} {RNA1509_54384, RNA815_12586}

Mlig455_048084 {REF} {Length: 2176} {TRANSSPLICED} {Pfam: Porphobilinogen deaminase, dipyromethane cofactor binding domain [PF01379.22, score=235.5]} {Human: ENSG00000256269, HMBS, hydroxymethylbilane synthase, [RH, Score=201, Expect=1e-63]; ENSG00000281702, HMBS, hydroxymethylbilane synthase, [RH, Score=201, Expect=1e-63]} {Mouse: ENSMUSG00000032126, Hmbs, hydroxymethylbilane synthase, [Score=199, Expect=2e-61]} {Dmel: FBgn0010786, l(3)02640, lethal (3) 02640, [Score=194, Expect=5e-57]} {Smed: dd_Smed_v6_1346_0_1, dd_Smed_v6_1346_0_1, [Score=192, Expect=2e-58]} {RNA1509_29548} {RNA1310_2114.1, RNA1509_29548} {RNA1509_29548, RNA815_12586}

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