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Results for MligTC455_43212

Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Annotation
MligTC455_43212 25 0.51 Mlig455_030578

Neo: -

Age: -

ZNF16 Mlig455_030578 {REF} {Length: 1942} {TRANSSPLICED} {Pfam: C2H2-type zinc finger [PF13894.8, score=55.4]; Zinc finger, C2H2 type [PF00096.28, score=51.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=38.5]; Zinc-finger of C2H2 type [PF12874.9, score=34.0]; C2H2 type zinc-finger (2 copies) [PF12756.9, score=25.9]; Zinc-fingers and homeoboxes C2H2 finger domain [PF18387.3, score=20.8]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=19.4]} {Human: ENSG00000170631, ZNF16, zinc finger protein 16, [Score=84.7, Expect=6e-17]; ENSG00000178175, ZNF366, zinc finger protein 366, [Score=82.0, Expect=4e-16]; ENSG00000213973, ZNF99, zinc finger protein 99, [Score=81.6, Expect=7e-16]; ENSG00000196350, ZNF729, zinc finger protein 729, [Score=80.5, Expect=2e-15]; ENSG00000180787, ZFP3, ZFP3 zinc finger protein, [Score=80.5, Expect=9e-16]} {Mouse: ENSMUSG00000059897, Zfp930, zinc finger protein 930, [Score=83.2, Expect=7e-17]; ENSMUSG00000050919, Zfp366, zinc finger protein 366, [Score=80.1, Expect=1e-15]} {Dmel: FBgn0038550, CG17801, [Score=68.9, Expect=2e-12]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [Score=52.4, Expect=1e-07]} {Smed: dd_Smed_v6_11840_0_1, dd_Smed_v6_11840_0_1, [Score=57.8, Expect=4e-09]} {RNA1509_14767, RNA1509_19735} {RNA1310_5349, RNA1509_19735} {RNA1509_19735, RNA815_28876}

Cumulative graph for MligTC455_43212

Region-enriched expression

Region logFC logCPM Pvalue FDR Specificity
RegionR1 -4.862 0.872 1.00000 1.00000
RegionR2 4.864 0.872 0.10254 0.39447
RegionR3 2.576 0.872 0.20809 0.74836
RegionR4 -1.395 0.872 0.88795 1.00000
RegionR5 0.637 0.872 0.48896 0.85217
RegionR6 -0.824 0.872 1.00000 1.00000
RegionR7 -0.448 0.872 1.00000 1.00000
RegionR8 -0.548 0.872 0.99978 1.00000

Regeneration-enriched expression

Region logFC logCPM PValue FDR Specificity
RegenerationR1 3.33 0.872 1.00000 1.00000
RegenerationR2 0.46 0.872 0.99472 1.00000
RegenerationR3 1.313 0.872 0.45237 0.83282
RegenerationR4 0.224 0.872 0.91277 1.00000
RegenerationR5 1.86 0.872 0.38222 0.78818
RegenerationR6 2.73 0.872 0.27319 0.62291
RegenerationBL 5.22 0.872 0.04774 0.25023
RegenerationTP 2.143 0.872 0.47889 0.88738


Genes with expression patterns similar to MligTC455_43212

Nr. Cluster Total UMI counts Global CPM Transcripts Categories Human homolog Σ Spearman correlations Int1 Int2 Int3 Reg1 Reg2 Reg3 Annotation
1. MligTC455_43212 25 0.51 Mlig455_030578

Neo: -

Age: -

ZNF16 2 - - 1.000 - 1.000 - Mlig455_030578 {REF} {Length: 1942} {TRANSSPLICED} {Pfam: C2H2-type zinc finger [PF13894.8, score=55.4]; Zinc finger, C2H2 type [PF00096.28, score=51.0]; Zinc-finger double-stranded RNA-binding [PF12171.10, score=38.5]; Zinc-finger of C2H2 type [PF12874.9, score=34.0]; C2H2 type zinc-finger (2 copies) [PF12756.9, score=25.9]; Zinc-fingers and homeoboxes C2H2 finger domain [PF18387.3, score=20.8]; Zinc finger C2H2-type, 3 repeats [PF18868.3, score=19.4]} {Human: ENSG00000170631, ZNF16, zinc finger protein 16, [Score=84.7, Expect=6e-17]; ENSG00000178175, ZNF366, zinc finger protein 366, [Score=82.0, Expect=4e-16]; ENSG00000213973, ZNF99, zinc finger protein 99, [Score=81.6, Expect=7e-16]; ENSG00000196350, ZNF729, zinc finger protein 729, [Score=80.5, Expect=2e-15]; ENSG00000180787, ZFP3, ZFP3 zinc finger protein, [Score=80.5, Expect=9e-16]} {Mouse: ENSMUSG00000059897, Zfp930, zinc finger protein 930, [Score=83.2, Expect=7e-17]; ENSMUSG00000050919, Zfp366, zinc finger protein 366, [Score=80.1, Expect=1e-15]} {Dmel: FBgn0038550, CG17801, [Score=68.9, Expect=2e-12]} {Celegans: WBGene00012639, fezf-1, FEZ Family zinc finger protein, [Score=52.4, Expect=1e-07]} {Smed: dd_Smed_v6_11840_0_1, dd_Smed_v6_11840_0_1, [Score=57.8, Expect=4e-09]} {RNA1509_14767, RNA1509_19735} {RNA1310_5349, RNA1509_19735} {RNA1509_19735, RNA815_28876}
2. MligTC455_42514 28 0.59 Mlig455_027746

Neo: -

Age: Up-Down-Down

KCNC2 1.905 - - 0.950 - 0.955 - Mlig455_027746 {REF} {Length: 2596} {Pfam: Ion transport protein [PF00520.33, score=123.8]; BTB/POZ domain [PF02214.24, score=86.8]; Ion channel [PF07885.18, score=37.1]} {Human: ENSG00000166006, KCNC2, potassium voltage-gated channel subfamily C member 2, [Score=284, Expect=2e-86]; ENSG00000129159, KCNC1, potassium voltage-gated channel subfamily C member 1, [Score=279, Expect=3e-85]; ENSG00000116396, KCNC4, potassium voltage-gated channel subfamily C member 4, [Score=270, Expect=2e-81]} {Mouse: ENSMUSG00000058975, Kcnc1, potassium voltage gated channel, Shaw-related subfamily, member 1, [Score=279, Expect=3e-85]; ENSMUSG00000035681, Kcnc2, potassium voltage gated channel, Shaw-related subfamily, member 2, [Score=270, Expect=2e-81]} {Dmel: FBgn0003386, Shaw, Shaker cognate w, [Score=280, Expect=7e-87]} {Celegans: WBGene00008819, shw-1, SHaW family of potassium channels, [Score=303, Expect=3e-94]} {Smed: dd_Smed_v6_13250_0_1, dd_Smed_v6_13250_0_1, [Score=286, Expect=3e-88]} {RNA1509_33421} {RNA1310_15684} {RNA815_16308}
3. MligTC455_54434 61 1.28 Mlig455_042860

Neo: -

Age: -

1.854 - - 0.958 - 0.896 - Mlig455_042860 {REF} {Length: 318} {Pfam: Integrase core domain [PF00665.28, score=28.8]} {Smed: dd_Smed_v6_11155_0_6, dd_Smed_v6_11155_0_6, [Score=47.0, Expect=1e-06]} {RNA1509_21400} {RNA1310_21556.1} {RNA815_2733.1}
4. MligTC455_36703 21 0.43 Mlig455_032688

Neo: -

Age: -

1.835 - - 0.981 - 0.854 - Mlig455_032688 {REF} {Length: 7822} {RNA1509_59817} {RNA1310_14959.1} {RNA815_22311}
5. MligTC455_19758 53 1.1 Mlig455_002464

Neo: -

Age: -

Region-enriched R2: 6.578/0.02863

1.822 - - 0.978 - 0.844 - Mlig455_002464 {REF} {Length: 2549} {RNA1310_38437} {RNA815_40458}
6. MligTC455_31098 35 0.73 Mlig455_025511, Mlig455_037030

Neo: -

Age: Down-Up-Down

1.779 - - 0.956 - 0.823 -

Mlig455_025511 {REF} {Length: 1662} {Smed: dd_Smed_v6_129_2_1, dd_Smed_v6_129_2_1, [Score=63.5, Expect=8e-11]} {RNA1509_32396} {RNA1310_22534} {RNA815_1171.1}

Mlig455_037030 {REF} {Length: 3378} {Pfam: Terpene synthase family 2, C-terminal metal binding [PF19086.2, score=18.7]} {Smed: dd_Smed_v6_129_2_1, dd_Smed_v6_129_2_1, [Score=85.5, Expect=7e-17]} {RNA1509_32396} {RNA1310_22534} {RNA815_1171.1}
7. MligTC455_25820 32 0.67 Mlig455_061208

Neo: -

Age: -

1.727 - - 0.975 - 0.752 - Mlig455_061208 {REF} {Length: 1262} {Celegans: WBGene00018026, F35A5.4, [Score=48.1, Expect=1e-06]} {RNA1310_123558}
8. MligTC455_50602 84 1.74 Mlig455_065088

Neo: -

Age: -

1.703 - - 0.951 - 0.752 - Mlig455_065088 {REF} {Length: 2765} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=129.5]} {Smed: dd_Smed_v6_37545_0_1, dd_Smed_v6_37545_0_1, [Score=67.8, Expect=6e-12]} {RNA1310_8235} {RNA815_10456.1}
9. MligTC455_29454 50 1.05 Mlig455_065107

Neo: -

Age: -

CHRNA10 1.694 - - 0.956 - 0.738 - Mlig455_065107 {REF} {Length: 3864} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=79.6]} {Human: ENSG00000129749, CHRNA10, cholinergic receptor nicotinic alpha 10 subunit, [Score=64.7, Expect=5e-11]; ENSG00000160716, CHRNB2, cholinergic receptor nicotinic beta 2 subunit, [Score=61.6, Expect=5e-10]} {Mouse: ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=71.6, Expect=2e-13]} {Celegans: WBGene00000051, acr-12, AcetylCholine Receptor; Nicotinic acetylcholine receptor-like subunit ACR-12, [Score=56.2, Expect=1e-08]} {Smed: dd_Smed_v6_12146_0_1, dd_Smed_v6_12146_0_1, [Score=74.7, Expect=6e-15]} {RNA1509_57562} {RNA1310_27363} {RNA815_5685.1}
10. MligTC455_36937 44 0.91 Mlig455_066629

Neo: -

Age: -

1.682 - - 0.957 - 0.725 - Mlig455_066629 {REF} {Length: 1530} {NoTransDecoderORF} {RNA1509_44223} {RNA1310_54802} {RNA815_64986}
11. MligTC455_50410 31 0.64 Mlig455_020239

Neo: -

Age: -

GRIA2 0.999 - - 0.999 - - - Mlig455_020239 {REF} {Length: 2096} {Pfam: Ligand-gated ion channel [PF00060.28, score=192.2]; Ligated ion channel L-glutamate- and glycine-binding site [PF10613.11, score=127.8]; Bacterial extracellular solute-binding proteins, family 3 [PF00497.22, score=91.1]} {Human: ENSG00000120251, GRIA2, glutamate ionotropic receptor AMPA type subunit 2, [Score=513, Expect=7e-173]; ENSG00000152578, GRIA4, glutamate ionotropic receptor AMPA type subunit 4, [Score=496, Expect=3e-166]; ENSG00000155511, GRIA1, glutamate ionotropic receptor AMPA type subunit 1, [Score=494, Expect=8e-167]; ENSG00000125675, GRIA3, glutamate ionotropic receptor AMPA type subunit 3, [Score=491, Expect=1e-164]} {Mouse: ENSMUSG00000033981, Gria2, glutamate receptor, ionotropic, AMPA2 (alpha 2), [Score=507, Expect=4e-171]; ENSMUSG00000025892, Gria4, glutamate receptor, ionotropic, AMPA4 (alpha 4), [Score=497, Expect=4e-167]; ENSMUSG00000020524, Gria1, glutamate receptor, ionotropic, AMPA1 (alpha 1), [Score=494, Expect=1e-165]; ENSMUSG00000001986, Gria3, glutamate receptor, ionotropic, AMPA3 (alpha 3), [Score=491, Expect=1e-164]} {Dmel: FBgn0038837, CG3822, [Score=432, Expect=1e-142]} {Celegans: WBGene00001612, glr-1, Glutamate receptor 1, [Score=459, Expect=5e-152]} {Smed: dd_Smed_v6_7562_0_1, dd_Smed_v6_7562_0_1, [Score=528, Expect=2e-179]} {RNA1509_56139} {RNA1310_38868} {RNA815_32684}
12. MligTC455_27066 95 1.99 Mlig455_008802

Neo: -

Age: -

0.997 - - 0.997 - - - Mlig455_008802 {REF} {Length: 1551} {NoTransDecoderORF} {RNA1509_44223} {RNA1310_54802} {RNA815_64986}
13. MligTC455_39455 42 0.87 Mlig455_036460

Neo: -

Age: -

0.995 - - 0.995 - - - Mlig455_036460 {REF} {Length: 1044} {NoTransDecoderORF} {RNA1509_44223} {RNA1310_54802} {RNA815_64986}
14. MligTC455_25445 12 0.24 Mlig455_021534

Neo: -

Age: Up-Down-Up

CACNA1D 0.994 - - 0.994 - - - Mlig455_021534 {REF} {Length: 4880} {Pfam: Ion transport protein [PF00520.33, score=359.2]; Voltage gated calcium channel IQ domain [PF08763.13, score=102.5]; Voltage-dependent L-type calcium channel, IQ-associated [PF16905.7, score=91.9]} {Human: ENSG00000157388, CACNA1D, calcium voltage-gated channel subunit alpha1 D, [Score=971, Expect=0.0]; ENSG00000081248, CACNA1S, calcium voltage-gated channel subunit alpha1 S, [Score=957, Expect=0.0]; ENSG00000151067, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=944, Expect=0.0]; ENSG00000285479, CACNA1C, calcium voltage-gated channel subunit alpha1 C, [Score=944, Expect=0.0]} {Mouse: ENSMUSG00000015968, Cacna1d, calcium channel, voltage-dependent, L type, alpha 1D subunit, [Score=971, Expect=0.0]; ENSMUSG00000051331, Cacna1c, calcium channel, voltage-dependent, L type, alpha 1C subunit, [Score=959, Expect=0.0]; ENSMUSG00000026407, Cacna1s, calcium channel, voltage-dependent, L type, alpha 1S subunit, [Score=958, Expect=0.0]} {Dmel: FBgn0001991, Ca-alpha1D, Ca[2+]-channel protein alpha[[1]] subunit D, [Score=989, Expect=0.0]} {Celegans: WBGene00001187, egl-19, Voltage-dependent L-type calcium channel subunit alpha, [Score=1053, Expect=0.0]} {Smed: dd_Smed_v6_8899_0_17, dd_Smed_v6_8899_0_17, [Score=1104, Expect=0.0]} {RNA1509_48072} {RNA1310_376.1} {RNA815_1126.1}
15. MligTC455_01014 50 1.04 Mlig455_061332

Neo: -

Age: -

0.993 - - 0.993 - - - Mlig455_061332 {REF} {Length: 923} {RNA1310_87489}
16. MligTC455_49922 36 0.76 Mlig455_049338

Neo: -

Age: Down-Down-Up

Region-enriched R2: 7.622/0.00496

0.993 - - 0.993 - - - Mlig455_049338 {REF} {Length: 971} {RNA1310_37449} {RNA815_3585}
17. MligTC455_12958 55 1.15 Mlig455_055683

Neo: -

Age: -

0.99 - - 0.990 - - - Mlig455_055683 {REF} {Length: 1376}
18. MligTC455_40199 64 1.33 Mlig455_026444, Mlig455_026477

Neo: -

Age: -

ASIC4 0.99 - - 0.990 - - -

Mlig455_026444 {REF} {Length: 2570} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=204.0]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=57.4, Expect=7e-08]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=53.9, Expect=5e-07]; ENSMUSG00000038276, Asic3, acid-sensing (proton-gated) ion channel 3, [Score=52.4, Expect=1e-06]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=69.7, Expect=5e-12]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=119, Expect=6e-28]} {RNA1310_21223} {RNA815_27174}

Mlig455_026477 {REF} {Length: 2402} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=160.5]} {Human: ENSG00000072182, ASIC4, acid sensing ion channel subunit family member 4, [Score=57.0, Expect=8e-08]} {Mouse: ENSMUSG00000033007, Asic4, acid-sensing (proton-gated) ion channel family member 4, [Score=53.9, Expect=5e-07]} {Celegans: WBGene00003174, mec-10, Degenerin mec-10, [Score=69.3, Expect=5e-12]} {Smed: dd_Smed_v6_12878_0_1, dd_Smed_v6_12878_0_1, [Score=93.6, Expect=9e-20]} {RNA1310_21223} {RNA815_27174}
19. MligTC455_03555 28 0.59 Mlig455_009266

Neo: -

Age: Up-Up-Down

0.989 - - 0.989 - - - Mlig455_009266 {REF} {Length: 1235} {NoTransDecoderORF} {RNA1509_42100} {RNA1310_56786} {RNA815_61979}
20. MligTC455_33449 53 1.11 Mlig455_048658, Mlig455_063410

Neo: -

Age: -

0.988 - - 0.988 - - -

Mlig455_048658 {REF} {Length: 1769} {Mouse: ENSMUSG00000020396, Nefh, neurofilament, heavy polypeptide, [Score=86.3, Expect=5e-17]} {RNA1509_51537} {RNA1310_24973} {RNA815_7432}

Mlig455_063410 {REF} {Length: 2520} {Pfam: Sporozoite P67 surface antigen [PF05642.13, score=19.6]} {RNA1509_51537} {RNA1310_24973} {RNA815_7432}
21. MligTC455_53813 46 0.96 Mlig455_038036

Neo: -

Age: Down-Down-Up

0.987 - - 0.987 - - - Mlig455_038036 {REF} {Length: 1511} {Smed: dd_Smed_v6_12148_0_3, dd_Smed_v6_12148_0_3, [Score=70.5, Expect=9e-14]} {RNA1310_21968} {RNA815_20437}
22. MligTC455_51807 28 0.59 Mlig455_046394

Neo: -

Age: -

GPSM2 0.986 - - 0.986 - - - Mlig455_046394 {REF} {Length: 3388} {Pfam: Tetratricopeptide repeat [PF13424.8, score=114.4]; Tetratricopeptide repeat [PF13176.8, score=96.0]; Tetratricopeptide repeat [PF00515.30, score=94.3]; GoLoco motif [PF02188.19, score=85.6]; Tetratricopeptide repeat [PF07719.19, score=55.0]; Tetratricopeptide repeat [PF13181.8, score=42.2]; Tetratricopeptide repeat [PF13374.8, score=32.8]; Rapsyn N-terminal myristoylation and linker region [PF10579.11, score=20.1]} {Human: ENSG00000121957, GPSM2, G protein signaling modulator 2, [RH, Score=542, Expect=0.0]} {Mouse: ENSMUSG00000027883, Gpsm2, G-protein signalling modulator 2 (AGS3-like, C. elegans), [RH, Score=532, Expect=1e-180]; ENSMUSG00000026930, Gpsm1, G-protein signalling modulator 1 (AGS3-like, C. elegans), [RH, Score=511, Expect=1e-172]} {Dmel: FBgn0040080, pins, partner of inscuteable, [RH, Score=530, Expect=2e-180]} {Celegans: WBGene00000092, ags-3, Activator of G protein Signalling, [RH, Score=266, Expect=7e-80]} {Smed: dd_Smed_v6_6548_1_1, dd_Smed_v6_6548_1_1, [RH, Score=477, Expect=1e-159]} {RNA1310_18538} {RNA815_41322}
23. MligTC455_37195 68 1.41 Mlig455_033638, Mlig455_033665

Neo: -

Age: Up-Down-Down

ASIC1 0.983 - - 0.983 - - -

Mlig455_033638 {REF} {Length: 3007} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=199.6]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=60.8, Expect=4e-09]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=55.8, Expect=1e-07]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=67.8, Expect=1e-11]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [RH, Score=483, Expect=5e-165]} {RNA1509_46829} {RNA1310_13649} {RNA815_15065}

Mlig455_033665 {REF} {Length: 4082} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=199.8]} {Human: ENSG00000110881, ASIC1, acid sensing ion channel subunit 1, [Score=62.0, Expect=2e-09]} {Mouse: ENSMUSG00000023017, Asic1, acid-sensing (proton-gated) ion channel 1, [Score=56.6, Expect=6e-08]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=68.6, Expect=9e-12]} {Smed: dd_Smed_v6_19599_0_1, dd_Smed_v6_19599_0_1, [RH, Score=483, Expect=8e-165]} {RNA1509_46829} {RNA1310_13649, RNA1509_46829} {RNA1509_46829, RNA815_15065}
24. MligTC455_40649 24 0.49 Mlig455_066232

Neo: -

Age: -

0.982 - - 0.982 - - - Mlig455_066232 {REF} {Length: 2453} {RNA1310_42980.1} {RNA815_47590}
25. MligTC455_10729 44 0.93 Mlig455_011434

Neo: -

Age: -

0.98 - - 0.980 - - - Mlig455_011434 {REF} {Length: 429} {NoTransDecoderORF} {RNA1509_36541} {RNA1310_37624} {RNA815_20457.1}
26. MligTC455_11804 40 0.84 Mlig455_049994, Mlig455_050022

Neo: -

Age: Up-Down-Up

0.98 - - 0.980 - - -

Mlig455_049994 {REF} {Length: 2541} {TRANSSPLICED} {RNA1310_33428} {RNA815_20155}

Mlig455_050022 {REF} {Length: 1815} {TRANSSPLICED} {RNA1310_33428} {RNA815_20155}
27. MligTC455_20200 47 0.97 Mlig455_021962

Neo: -

Age: -

KCNMA1 0.98 - - 0.980 - - - Mlig455_021962 {REF} {Length: 3749} {Pfam: Calcium-activated BK potassium channel alpha subunit [PF03493.20, score=76.1]; Ion channel [PF07885.18, score=61.3]; Ion transport protein [PF00520.33, score=34.6]; Ligand-gated ion channel [PF00060.28, score=23.9]} {Human: ENSG00000156113, KCNMA1, potassium calcium-activated channel subfamily M alpha 1, [Score=634, Expect=0.0]} {Mouse: ENSMUSG00000063142, Kcnma1, potassium large conductance calcium-activated channel, subfamily M, alpha member 1, [Score=628, Expect=0.0]} {Dmel: FBgn0003429, slo, slowpoke, [Score=449, Expect=8e-139]} {Celegans: WBGene00004830, slo-1, Calcium-activated potassium channel slo-1, [Score=444, Expect=2e-137]} {Smed: dd_Smed_v6_5509_0_1, dd_Smed_v6_5509_0_1, [Score=610, Expect=0.0]} {RNA1310_43306.1} {RNA815_38585}
28. MligTC455_39719 44 0.92 Mlig455_063602

Neo: -

Age: -

MPDZ 0.979 - - 0.979 - - - Mlig455_063602 {REF} {Length: 2307} {Pfam: PDZ domain [PF00595.26, score=187.6]; PDZ domain [PF17820.3, score=85.4]; PDZ domain [PF13180.8, score=85.1]} {Human: ENSG00000107186, MPDZ, multiple PDZ domain crumbs cell polarity complex component, [Score=244, Expect=9e-70]} {Mouse: ENSMUSG00000028402, Mpdz, multiple PDZ domain protein, [Score=237, Expect=7e-67]} {Dmel: FBgn0263289, scrib, scribbled, [Score=88.6, Expect=6e-18]} {Celegans: WBGene00003404, mpz-1, Multiple PDZ domain protein, [Score=137, Expect=7e-35]} {Smed: dd_Smed_v6_4520_0_1, dd_Smed_v6_4520_0_1, [Score=147, Expect=2e-37]} {RNA1310_8275.3} {RNA815_16615}
29. MligTC455_11168 10 0.21 Mlig455_015184

Neo: -

Age: -

0.978 - - 0.978 - - - Mlig455_015184 {REF} {Length: 1552} {NoTransDecoderORF} {RNA1509_44393} {RNA1310_60529.2} {RNA815_62333}
30. MligTC455_50219 35 0.73 Mlig455_006785

Neo: -

Age: -

0.976 - - 0.976 - - - Mlig455_006785 {REF} {Length: 787} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=67.2]} {Smed: dd_Smed_v6_17245_0_1, dd_Smed_v6_17245_0_1, [Score=55.5, Expect=9e-10]} {RNA1509_47645} {RNA1310_28371} {RNA815_4577.1}
31. MligTC455_33046 67 1.4 Mlig455_013269, Mlig455_032133, Mlig455_032300, Mlig455_054137, Mlig455_056421, Mlig455_065759

Neo: -

Age: Up-Down-Down

0.975 - - 0.975 - - -

Mlig455_013269 {REF} {Length: 847} {Pfam: Recombination endonuclease VII [PF02945.17, score=31.7]} {Celegans: WBGene00016348, C33E10.6, [Score=80.9, Expect=4e-17]} {Smed: dd_Smed_v6_9974_1_5, dd_Smed_v6_9974_1_5, [Score=93.6, Expect=1e-21]} {RNA1509_39151} {RNA1310_2387} {RNA815_59939}

Mlig455_032133 {REF} {Length: 905} {Pfam: Recombination endonuclease VII [PF02945.17, score=32.0]; Borrelia P83/100 protein [PF05262.13, score=18.2]} {Celegans: WBGene00016348, C33E10.6, [Score=82.0, Expect=4e-17]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=95.9, Expect=6e-22]} {RNA1509_39151} {RNA1310_2387} {RNA815_59939}

Mlig455_032300 {REF} {Length: 1525} {Pfam: Borrelia P83/100 protein [PF05262.13, score=21.0]; Phosphatidylinositol-4-phosphate 5-Kinase [PF01504.20, score=19.4]; Contractile injection system tape measure protein [PF19268.1, score=18.6]} {RNA1509_13774} {RNA1310_41660} {RNA815_55778}

Mlig455_054137 {REF} {Length: 899} {Pfam: Recombination endonuclease VII [PF02945.17, score=31.1]} {Celegans: WBGene00016348, C33E10.6, [Score=80.1, Expect=1e-16]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=111, Expect=3e-27]} {RNA1509_39151} {RNA1310_2387} {RNA815_19338}

Mlig455_056421 {REF} {Length: 1944} {Pfam: Transcription factor IIA, alpha/beta subunit [PF03153.15, score=21.4]} {Smed: dd_Smed_v6_14361_0_10, dd_Smed_v6_14361_0_10, [Score=51.2, Expect=7e-09]} {RNA1509_21624} {RNA1310_2387} {RNA815_19338}

Mlig455_065759 {REF} {Length: 1453} {Pfam: Recombination endonuclease VII [PF02945.17, score=30.3]} {Celegans: WBGene00016348, C33E10.6, [Score=101, Expect=9e-23]} {Smed: dd_Smed_v6_9974_1_2, dd_Smed_v6_9974_1_2, [Score=142, Expect=2e-36]} {RNA1509_39151} {RNA1310_2387} {RNA815_19338}
32. MligTC455_41541 30 0.62 Mlig455_064895

Neo: -

Age: -

GLUL 0.975 - - - - 0.975 - Mlig455_064895 {REF} {Length: 1633} {Pfam: Glutamine synthetase, catalytic domain [PF00120.26, score=57.2]; Glutamine synthetase, beta-Grasp domain [PF03951.21, score=45.1]} {Human: ENSG00000135821, GLUL, glutamate-ammonia ligase, [RH, Score=503, Expect=4e-177]} {Mouse: ENSMUSG00000026473, Glul, glutamate-ammonia ligase (glutamine synthetase), [RH, Score=503, Expect=2e-179]} {Dmel: FBgn0001145, Gs2, Glutamine synthetase 2, [RH, Score=510, Expect=0.0]} {Celegans: WBGene00001604, gln-3, Glutamine synthetase, [RH, Score=511, Expect=0.0]} {Smed: dd_Smed_v6_896_0_1, dd_Smed_v6_896_0_1, [RH, Score=546, Expect=0.0]} {RNA1509_47000} {RNA1310_22329.1, RNA1509_47000} {RNA1509_47000, RNA815_4116.6}
33. MligTC455_26259 76 1.59 Mlig455_026466

Neo: -

Age: -

SSUH2 0.973 - - - - 0.973 - Mlig455_026466 {REF} {Length: 2558} {Human: ENSG00000125046, SSUH2, ssu-2 homolog (C. elegans), [Score=211, Expect=9e-64]} {Mouse: ENSMUSG00000034387, Ssu2, ssu-2 homolog (C. elegans), [Score=168, Expect=6e-48]} {Celegans: WBGene00013455, ssu-2, Suppressor of Stomatin mutant Uncoordination, [Score=67.8, Expect=3e-12]} {RNA1509_35931} {RNA1310_33249} {RNA815_15534}
34. MligTC455_50304 17 0.35 Mlig455_067422

Neo: -

Age: -

0.973 - - 0.973 - - - Mlig455_067422 {REF} {Length: 751} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_51606} {RNA1310_82384} {RNA815_44872}
35. MligTC455_39013 53 1.1 Mlig455_030082

Neo: -

Age: Up-Down-Down

PLCB1 0.971 - - 0.971 - - - Mlig455_030082 {REF} {Length: 5740} {Pfam: Phosphatidylinositol-specific phospholipase C, X domain [PF00388.21, score=199.2]; Phosphatidylinositol-specific phospholipase C, Y domain [PF00387.21, score=124.4]; PH domain [PF17787.3, score=120.6]; Phosphoinositide-specific phospholipase C, efhand-like [PF09279.13, score=33.9]} {Human: ENSG00000182621, PLCB1, phospholipase C beta 1, [RH, Score=826, Expect=0.0]; ENSG00000149782, PLCB3, phospholipase C beta 3, [RH, Score=824, Expect=0.0]} {Mouse: ENSMUSG00000051177, Plcb1, phospholipase C, beta 1, [RH, Score=826, Expect=0.0]; ENSMUSG00000024960, Plcb3, phospholipase C, beta 3, [RH, Score=813, Expect=0.0]} {Dmel: FBgn0262738, norpA, no receptor potential A, [Score=670, Expect=0.0]} {Celegans: WBGene00001177, egl-8, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8, [Score=680, Expect=0.0]} {Smed: dd_Smed_v6_3221_0_1, dd_Smed_v6_3221_0_1, [Score=724, Expect=0.0]} {RNA1509_47106} {RNA1310_7555, RNA1509_47106} {RNA1509_47106, RNA815_2033}
36. MligTC455_29096 98 2.03 Mlig455_065347

Neo: -

Age: logFC(26M/2M)=2.647

0.97 - - 0.970 - - - Mlig455_065347 {REF} {Length: 4150} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=61.9]} {Smed: dd_Smed_v6_13734_0_20, dd_Smed_v6_13734_0_20, [Score=49.3, Expect=2e-06]} {RNA1509_13072} {RNA1310_4523} {RNA815_1327.1}
37. MligTC455_34656 48 1 Mlig455_058210

Neo: Irradiation

Age: Up-Down-Down, logFC(26M/2M)=-0.537

Region-enriched R2: 5.874/0.03747

PPEF1 0.97 - - 0.970 - - - Mlig455_058210 {REF} {Length: 2937} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=90.9]; EF-hand domain pair [PF13499.8, score=63.3]; EF hand [PF00036.34, score=53.9]; PPP5 TPR repeat region [PF08321.14, score=45.9]; EF-hand domain pair [PF13833.8, score=45.7]; EF-hand domain [PF13405.8, score=43.1]; EF hand [PF13202.8, score=41.7]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.2]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [Score=533, Expect=0.0]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [Score=512, Expect=1e-174]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [Score=489, Expect=6e-166]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [Score=563, Expect=0.0]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [Score=642, Expect=0.0]} {RNA1509_3508} {RNA1310_11714.1} {RNA815_4130}
38. MligTC455_51760 18 0.38 Mlig455_051796

Neo: -

Age: -

CNBD2 0.97 - - 0.970 - - - Mlig455_051796 {REF} {Length: 2614} {Pfam: Cyclic nucleotide-binding domain [PF00027.31, score=74.7]} {Human: ENSG00000149646, CNBD2, cyclic nucleotide binding domain containing 2, [Score=67.4, Expect=2e-11]; ENSG00000185532, PRKG1, protein kinase cGMP-dependent 1, [Score=64.3, Expect=4e-10]} {Mouse: ENSMUSG00000052920, Prkg1, protein kinase, cGMP-dependent, type I, [Score=64.7, Expect=2e-10]; ENSMUSG00000038085, Cnbd2, cyclic nucleotide binding domain containing 2, [Score=63.9, Expect=2e-10]} {Dmel: FBgn0259243, Pka-R1, Protein kinase, cAMP-dependent, regulatory subunit type 1, [Score=57.4, Expect=1e-08]} {Celegans: WBGene00015650, pkg-2, Protein Kinase, cGMP-dependent, [Score=61.2, Expect=1e-09]} {Smed: dd_Smed_v6_17565_0_1, dd_Smed_v6_17565_0_1, [Score=174, Expect=1e-46]} {RNA1310_33768} {RNA815_47620}
39. MligTC455_26896 68 1.41 Mlig455_044263

Neo: -

Age: logFC(26M/2M)=1.950

0.969 - - 0.969 - - - Mlig455_044263 {REF} {Length: 2369} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_6921} {RNA1310_72140} {RNA815_9260.1}
40. MligTC455_34655 89 1.86 Mlig455_058020, Mlig455_058176

Neo: -

Age: -

Region-enriched R2: 5.798/0.00826

PPEF1 0.969 - - 0.969 - - -

Mlig455_058020 {REF} {Length: 3007} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=84.9]; EF-hand domain pair [PF13499.8, score=77.8]; EF hand [PF00036.34, score=66.0]; EF-hand domain pair [PF13833.8, score=52.1]; EF-hand domain [PF13405.8, score=48.4]; EF hand [PF13202.8, score=38.2]; PPP5 TPR repeat region [PF08321.14, score=37.0]; EF-hand domain [PF14658.8, score=23.0]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=20.4]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [Score=416, Expect=2e-138]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [Score=413, Expect=9e-138]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [Score=404, Expect=3e-134]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [Score=455, Expect=2e-155]} {Smed: dd_Smed_v6_11874_0_2, dd_Smed_v6_11874_0_2, [Score=516, Expect=2e-178]} {RNA1509_3508} {RNA1310_10928.2} {RNA815_11707}

Mlig455_058176 {REF} {Length: 3371} {Pfam: Calcineurin-like phosphoesterase [PF00149.30, score=102.6]; EF-hand domain pair [PF13499.8, score=72.6]; EF hand [PF00036.34, score=64.2]; EF-hand domain pair [PF13833.8, score=51.3]; EF-hand domain [PF13405.8, score=46.1]; EF hand [PF13202.8, score=36.7]; PPP5 TPR repeat region [PF08321.14, score=36.6]; EF-hand domain [PF14658.8, score=26.5]; IQ calmodulin-binding motif [PF00612.29, score=21.3]; Cytoskeletal-regulatory complex EF hand [PF12763.9, score=19.8]} {Human: ENSG00000086717, PPEF1, protein phosphatase with EF-hand domain 1, [RH, Score=546, Expect=0.0]} {Mouse: ENSMUSG00000062168, Ppef1, protein phosphatase with EF hand calcium-binding domain 1, [Score=520, Expect=3e-177]} {Dmel: FBgn0265959, rdgC, retinal degeneration C, [Score=529, Expect=2e-180]} {Celegans: WBGene00003969, pef-1, Serine/threonine-protein phosphatase with EF-hands pef-1, [Score=598, Expect=0.0]} {Smed: dd_Smed_v6_11874_0_1, dd_Smed_v6_11874_0_1, [Score=671, Expect=0.0]} {RNA1509_3508} {RNA1310_10928.2} {RNA815_11707}
41. MligTC455_35552 32 0.67 Mlig455_035296

Neo: -

Age: -

SCNN1B 0.968 - - 0.968 - - - Mlig455_035296 {REF} {Length: 3475} {Pfam: Amiloride-sensitive sodium channel [PF00858.26, score=192.5]} {Human: ENSG00000168447, SCNN1B, sodium channel epithelial 1 beta subunit, [Score=64.7, Expect=5e-10]} {Mouse: ENSMUSG00000030873, Scnn1b, sodium channel, nonvoltage-gated 1 beta, [Score=57.8, Expect=4e-08]} {Celegans: WBGene00006832, unc-105, Degenerin-like protein unc-105, [Score=77.0, Expect=2e-14]} {Smed: dd_Smed_v6_22997_0_1, dd_Smed_v6_22997_0_1, [Score=357, Expect=9e-114]} {RNA1509_53211} {RNA1310_6642.3, RNA1509_53211} {RNA1509_53211, RNA815_12322}
42. MligTC455_14499 35 0.73 Mlig455_052131

Neo: -

Age: -

0.967 - - - - 0.967 - Mlig455_052131 {REF} {Length: 203} {NoTransDecoderORF} {RNA1310_10102} {RNA815_11180}
43. MligTC455_21847 88 1.83 Mlig455_002908, Mlig455_032608

Neo: -

Age: -

0.967 - - - - 0.967 -

Mlig455_002908 {REF} {Length: 4389} {NoTransDecoderORF} {RNA1509_40232} {RNA1310_33581} {RNA815_1090.1}

Mlig455_032608 {REF} {Length: 3828} {NoTransDecoderORF} {RNA1509_35989} {RNA1310_3490.1, RNA1509_35989} {RNA1509_35989, RNA815_52019}
44. MligTC455_29095 291 6.07 Mlig455_008520, Mlig455_062905, Mlig455_064803

Neo: -

Age: -

0.967 - - 0.967 - - -

Mlig455_008520 {REF} {Length: 5586} {RNA1509_55508} {RNA1310_19597} {RNA815_1327.1}

Mlig455_062905 {REF} {Length: 2632} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=121.7]; Endonuclease-reverse transcriptase [PF14529.8, score=48.8]} {Smed: dd_Smed_v6_16441_0_5, dd_Smed_v6_16441_0_5, [Score=105, Expect=8e-24]} {RNA1509_13072, RNA1509_29940} {RNA1310_4523, RNA1509_29940} {RNA1509_29940, RNA815_17419}

Mlig455_064803 {REF} {Length: 1273} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=121.7]; Endonuclease-reverse transcriptase [PF14529.8, score=48.8]} {Smed: dd_Smed_v6_16441_0_5, dd_Smed_v6_16441_0_5, [Score=105, Expect=8e-24]} {RNA1509_13072} {RNA1310_989.1} {RNA815_1327.1}
45. MligTC455_44159 80 1.67 Mlig455_019040, Mlig455_055663

Neo: -

Age: Down-Up-Up

ADRB1, GALR3 0.967 - - 0.967 - - -

Mlig455_019040 {REF} {Length: 1804} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=78.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=31.3]} {Human: ENSG00000043591, ADRB1, adrenoceptor beta 1, [Score=52.8, Expect=5e-07]} {Mouse: ENSMUSG00000034987, Hrh2, histamine receptor H2, [Score=47.8, Expect=1e-05]} {Dmel: FBgn0038874, ETHR, [Score=49.3, Expect=3e-06]} {Celegans: WBGene00017661, frpr-6, FMRFamide Peptide Receptor family, [Score=54.3, Expect=5e-08]} {Smed: dd_Smed_v6_19933_0_1, dd_Smed_v6_19933_0_1, [RH, Score=124, Expect=9e-33]} {RNA1310_47955} {RNA815_45615}

Mlig455_055663 {REF} {Length: 1667} {Pfam: 7 transmembrane receptor (rhodopsin family) [PF00001.23, score=47.3]; Serpentine type 7TM GPCR chemoreceptor Srsx [PF10320.11, score=27.2]} {Human: ENSG00000128310, GALR3, galanin receptor 3, [Score=50.1, Expect=2e-06]} {Smed: dd_Smed_v6_14726_0_1, dd_Smed_v6_14726_0_1, [Score=103, Expect=6e-25]} {RNA1310_86586} {RNA815_45615}
46. MligTC455_21785 107 2.24 Mlig455_005064

Neo: -

Age: Up-Down-Up, logFC(26M/2M)=-0.389

KRIT1 0.966 - - - - 0.966 - Mlig455_005064 {REF} {Length: 4037} {TRANSSPLICED} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=53.0]; Ankyrin repeats (many copies) [PF13857.8, score=50.3]; Ankyrin repeats (many copies) [PF13637.8, score=40.3]; Ankyrin repeat [PF00023.32, score=35.8]; Ankyrin repeat [PF13606.8, score=32.7]; FERM central domain [PF00373.20, score=26.3]} {Human: ENSG00000001631, KRIT1, KRIT1, ankyrin repeat containing, [RH, Score=218, Expect=2e-60]; ENSG00000285953, AC000120.3, novel protein, [RH, Score=209, Expect=2e-57]} {Mouse: ENSMUSG00000000600, Krit1, KRIT1, ankyrin repeat containing, [RH, Score=207, Expect=1e-56]} {Dmel: FBgn0029137, Patsas, [Score=51.6, Expect=2e-06]} {Celegans: WBGene00013955, kri-1, KRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homolog; Krev interaction trapped/cerebral cavernous malformation 1 isoform a, [RH, Score=85.9, Expect=5e-17]} {Smed: dd_Smed_v6_10935_0_1, dd_Smed_v6_10935_0_1, [RH, Score=137, Expect=3e-33]} {RNA1509_17918} {RNA1310_6799, RNA1509_17918} {RNA1509_17918, RNA815_1724}
47. MligTC455_19187 156 3.26 Mlig455_018418

Neo: -

Age: -

Region-enriched R2: 2.105/0.03594

NRXN1 0.965 - - 0.965 - - - Mlig455_018418 {REF} {Length: 6075} {Pfam: Laminin G domain [PF02210.26, score=290.6]; Laminin G domain [PF00054.25, score=213.6]; Syndecan domain [PF01034.22, score=25.6]; EGF-like domain [PF00008.29, score=22.7]} {Human: ENSG00000179915, NRXN1, neurexin 1, [RH, Score=396, Expect=2e-114]} {Mouse: ENSMUSG00000024109, Nrxn1, neurexin I, [Score=408, Expect=3e-119]} {Dmel: FBgn0038975, Nrx-1, Neurexin 1, [Score=315, Expect=2e-87]} {Celegans: WBGene00007799, nrx-1, NRX-1 beta isoform; NeuReXin related, [Score=119, Expect=9e-27]} {Smed: dd_Smed_v6_13697_0_1, dd_Smed_v6_13697_0_1, [RH, Score=429, Expect=2e-128]} {RNA1509_34878} {RNA1310_1222.1} {RNA815_16735}
48. MligTC455_30572 88 1.82 Mlig455_009374, Mlig455_026650

Neo: -

Age: Down-Down-Down

NYNRIN 0.965 - - 0.965 - - -

Mlig455_009374 {REF} {Length: 592} {Pfam: RNase H-like domain found in reverse transcriptase [PF17917.3, score=104.1]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=103.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=57.8]; Integrase zinc binding domain [PF17921.3, score=56.9]; Integrase core domain [PF00665.28, score=46.3]; gag-polyprotein putative aspartyl protease [PF13975.8, score=22.7]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=71.2, Expect=8e-12]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=72.0, Expect=3e-12]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=262, Expect=3e-73]} {RNA1509_8906} {RNA1310_1712.2} {RNA815_474.1}

Mlig455_026650 {REF} {Length: 3906} {Pfam: RNase H-like domain found in reverse transcriptase [PF17917.3, score=104.1]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=103.6]; Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=57.8]; Integrase zinc binding domain [PF17921.3, score=56.9]; Integrase core domain [PF00665.28, score=46.3]; gag-polyprotein putative aspartyl protease [PF13975.8, score=22.7]} {Human: ENSG00000205978, NYNRIN, NYN domain and retroviral integrase containing, [Score=71.2, Expect=8e-12]} {Mouse: ENSMUSG00000075592, Nynrin, NYN domain and retroviral integrase containing, [Score=72.0, Expect=3e-12]} {Smed: dd_Smed_v6_3718_0_2, dd_Smed_v6_3718_0_2, [Score=262, Expect=3e-73]} {RNA1509_8906} {RNA1310_1712.3} {RNA815_474.1}
49. MligTC455_39725 21 0.43 Mlig455_054561, Mlig455_063924

Neo: -

Age: -

0.965 - - 0.965 - - -

Mlig455_054561 {REF} {Length: 1204} {NoTransDecoderORF} {RNA1509_40399} {RNA1310_55528} {RNA815_53136}

Mlig455_063924 {REF} {Length: 985} {RNA1509_21181} {RNA1310_49997} {RNA815_32302}
50. MligTC455_40779 191 3.98 Mlig455_000277, Mlig455_035731, Mlig455_058356

Neo: -

Age: -

Region-enriched R4: 3.665/0.04268

0.965 - - 0.965 - - -

Mlig455_000277 {REF} {Length: 1048} {RNA1509_16458} {RNA1310_43664.1} {RNA815_23166}

Mlig455_035731 {REF} {Length: 1048} {RNA1509_16458} {RNA1310_43664.1} {RNA815_23166}

Mlig455_058356 {REF} {Length: 1050} {RNA1509_16458} {RNA1310_43664.1} {RNA815_23166}
51. MligTC455_32521 203 4.23 Mlig455_040932

Neo: -

Age: Down-Down-Up

Region-enriched R8: 3.877/0.00012
Region-enriched R2: 3.007/0.00212

0.963 - - 0.963 - - - Mlig455_040932 {REF} {Length: 1862} {RNA1310_21335.1} {RNA815_57481}
52. MligTC455_44725 67 1.4 Mlig455_024194

Neo: -

Age: -

0.963 - - 0.963 - - - Mlig455_024194 {REF} {Length: 956} {RNA1310_84543} {RNA815_47586}
53. MligTC455_12961 32 0.66 Mlig455_042954

Neo: Germline

Age: -

0.96 - - - - 0.960 - Mlig455_042954 {REF} {Length: 9103} {Pfam: Retrotransposon gag protein [PF03732.19, score=25.9]; Zinc knuckle [PF00098.25, score=23.7]} {RNA1509_48613} {RNA1310_992.1, RNA1509_48613} {RNA1509_48613, RNA815_7963}
54. MligTC455_29264 78 1.62 Mlig455_061707

Neo: -

Age: logFC(26M/2M)=1.238

0.96 - - 0.960 - - - Mlig455_061707 {REF} {Length: 5671} {Pfam: Zinc knuckle [PF00098.25, score=33.9]} {Celegans: WBGene00017210, F07E5.5, [Score=53.5, Expect=3e-07]} {RNA1509_12781} {RNA1310_541.1} {RNA815_23.1}
55. MligTC455_27678 355 7.4 Mlig455_070610

Neo: -

Age: -

Region-specific R2: 4.724

Region-enriched R2: 3.766/0.00062

0.958 - - 0.958 - - - Mlig455_070610 {REF} {Length: 725} {RNA1509_17468, RNA1509_34237} {RNA1310_59474, RNA1509_17468, RNA1509_34237} {RNA1509_17468, RNA1509_34237, RNA815_28024}
56. MligTC455_36910 84 1.75 Mlig455_031683

Neo: -

Age: -

0.958 - - - - 0.958 - Mlig455_031683 {REF} {Length: 4716} {RNA1509_36080} {RNA1310_44068, RNA1509_36080} {RNA1509_36080, RNA815_39601}
57. MligTC455_40781 153 3.2 Mlig455_024109, Mlig455_063982

Neo: -

Age: -

0.958 - - 0.958 - - -

Mlig455_024109 {REF} {Length: 1081} {RNA1509_16458} {RNA1310_43664.1, RNA1509_16458} {RNA1509_16458, RNA815_23166}

Mlig455_063982 {REF} {Length: 3562} {RNA1509_16458} {RNA1310_30070} {RNA815_23166}
58. MligTC455_25058 7 0.15 Mlig455_029944

Neo: -

Age: Up-Down-Down

HERC2 0.957 - - - - 0.957 - Mlig455_029944 {REF} {Length: 9352} {Pfam: Regulator of chromosome condensation (RCC1) repeat [PF00415.20, score=324.8]; HECT-domain (ubiquitin-transferase) [PF00632.27, score=182.7]; Regulator of chromosome condensation (RCC1) repeat [PF13540.8, score=136.1]} {Human: ENSG00000128731, HERC2, HECT and RLD domain containing E3 ubiquitin protein ligase 2, [RH, Score=1546, Expect=0.0]; ENSG00000276802, HERC2, HECT and RLD domain containing E3 ubiquitin protein ligase 2, [RH, Score=1545, Expect=0.0]} {Mouse: ENSMUSG00000030451, Herc2, HECT and RLD domain containing E3 ubiquitin protein ligase 2, [RH, Score=1470, Expect=0.0]} {Dmel: FBgn0031107, HERC2, HECT and RLD domain containing protein 2, [RH, Score=1266, Expect=0.0]} {Celegans: WBGene00022358, Y92H12A.2, E3 ubiquitin-protein ligase, [Score=116, Expect=8e-27]} {Smed: dd_Smed_v6_3885_0_1, dd_Smed_v6_3885_0_1, [RH, Score=1101, Expect=0.0]} {RNA1509_2217, RNA1509_56877} {RNA1310_95.1, RNA1509_56877} {RNA1509_56877, RNA815_620}
59. MligTC455_28723 57 1.19 Mlig455_038771

Neo: -

Age: -

0.957 - - 0.957 - - - Mlig455_038771 {REF} {Length: 3385} {NoTransDecoderORF} {RNA1509_2485} {RNA1310_64926} {RNA815_131.1}
60. MligTC455_36204 94 1.96 Mlig455_035702, Mlig455_050258, Mlig455_053594

Neo: -

Age: -

RTL1 0.957 - - 0.957 - - -

Mlig455_035702 {REF} {Length: 1760} {Pfam: RNase H [PF00075.26, score=29.7]; gag-polyprotein putative aspartyl protease [PF13975.8, score=21.8]} {RNA1509_47233} {RNA1310_58380} {RNA815_3478.1}

Mlig455_050258 {REF} {Length: 1380} {Smed: dd_Smed_v6_94688_0_1, dd_Smed_v6_94688_0_1, [Score=79.0, Expect=1e-18]} {RNA1509_41237} {RNA1310_70866} {RNA815_30267}

Mlig455_053594 {REF} {Length: 5265} {Pfam: Reverse transcriptase (RNA-dependent DNA polymerase) [PF00078.29, score=93.8]; RNase H-like domain found in reverse transcriptase [PF17919.3, score=88.4]; RNase H-like domain found in reverse transcriptase [PF17917.3, score=84.6]; Integrase zinc binding domain [PF17921.3, score=69.8]; H2C2 zinc finger [PF09337.12, score=23.5]} {Human: ENSG00000254656, RTL1, retrotransposon Gag like 1, [Score=107, Expect=2e-23]} {Mouse: ENSMUSG00000085925, Rtl1, retrotransposon Gaglike 1, [RH, Score=104, Expect=8e-23]; ENSMUSG00000098639, Rtl1, retrotransposon Gaglike 1, [RH, Score=104, Expect=8e-23]} {Smed: dd_Smed_v6_1574_6_44, dd_Smed_v6_1574_6_44, [Score=241, Expect=1e-72]} {RNA1509_41237} {RNA1310_4795.1} {RNA815_37092}
61. MligTC455_29632 21 0.44 Mlig455_054227

Neo: -

Age: Down-Up-Down

ANKRD50 0.956 - - 0.956 - - - Mlig455_054227 {REF} {Length: 5889} {Pfam: Ankyrin repeats (3 copies) [PF12796.9, score=128.1]; Ankyrin repeats (many copies) [PF13637.8, score=114.1]; Ankyrin repeat [PF13606.8, score=90.5]; Ankyrin repeats (many copies) [PF13857.8, score=86.8]; Ankyrin repeat [PF00023.32, score=45.5]; Mab-21 protein [PF03281.16, score=31.7]} {Human: ENSG00000151458, ANKRD50, ankyrin repeat domain 50, [Score=94.7, Expect=9e-19]} {Mouse: ENSMUSG00000044864, Ankrd50, ankyrin repeat domain 50, [Score=95.9, Expect=2e-19]} {Dmel: FBgn0041096, rols, rolling pebbles, [Score=82.0, Expect=3e-15]} {Celegans: WBGene00006616, trp-4, TRP (Transient receptor potential) channel family, [Score=69.7, Expect=2e-11]} {Smed: dd_Smed_v6_6779_0_1, dd_Smed_v6_6779_0_1, [Score=83.2, Expect=9e-16]} {RNA1509_24245, RNA1509_27730, RNA1509_49510, RNA1509_49520} {RNA1310_4721, RNA1509_24245, RNA1509_49510, RNA1509_49520} {RNA1509_24245, RNA1509_49510, RNA1509_49520, RNA815_2426.1}
62. MligTC455_07428 12 0.25 Mlig455_055209

Neo: -

Age: -

0.955 - - 0.955 - - - Mlig455_055209 {REF} {Length: 759} {RNA1310_50531} {RNA815_29422}
63. MligTC455_10602 7 0.14 Mlig455_069165

Neo: -

Age: -

0.955 - - 0.955 - - - Mlig455_069165 {REF} {Length: 609}
64. MligTC455_20769 86 1.8 Mlig455_058483

Neo: -

Age: Up-Down-Down

CALCR 0.955 - - 0.955 - - - Mlig455_058483 {REF} {Length: 1844} {Pfam: 7 transmembrane receptor (Secretin family) [PF00002.26, score=149.2]; Hormone receptor domain [PF02793.24, score=37.6]} {Human: ENSG00000004948, CALCR, calcitonin receptor, [Score=140, Expect=3e-36]} {Mouse: ENSMUSG00000023964, Calcr, calcitonin receptor, [Score=147, Expect=1e-38]} {Dmel: FBgn0260753, Pdfr, Pigment-dispersing factor receptor, [Score=213, Expect=5e-62]} {Celegans: WBGene00015735, pdfr-1, Calcitonin receptor-like protein 1, [Score=178, Expect=4e-50]} {Smed: dd_Smed_v6_22246_0_1, dd_Smed_v6_22246_0_1, [RH, Score=199, Expect=4e-59]} {RNA1310_16931.2} {RNA815_17279}
65. MligTC455_21942 54 1.12 Mlig455_040670

Neo: -

Age: -

0.955 - - - - 0.955 - Mlig455_040670 {REF} {Length: 1501} {RNA1509_21400} {RNA1310_43853} {RNA815_2733.1}
66. MligTC455_34815 30 0.63 Mlig455_020979

Neo: -

Age: -

0.955 - - 0.955 - - - Mlig455_020979 {REF} {Length: 1394} {RNA1310_37266}
67. MligTC455_39736 474 9.86 Mlig455_014716

Neo: -

Age: Up-Down-Up

0.954 - - - - 0.954 - Mlig455_014716 {REF} {Length: 3097} {TRANSSPLICED} {Pfam: Domain of unknown function (DUF4537) [PF15057.8, score=61.8]; von Willebrand factor type A domain [PF13768.8, score=19.6]} {Smed: dd_Smed_v6_10837_0_1, dd_Smed_v6_10837_0_1, [RH, Score=97.4, Expect=1e-20]} {RNA1509_28750} {RNA1310_4730} {RNA815_8808}
68. MligTC455_08961 17 0.36 Mlig455_062229

Neo: -

Age: -

0.953 - - - - 0.953 - Mlig455_062229 {REF} {Length: 871} {NoTransDecoderORF} {RNA1310_57807.1}
69. MligTC455_10413 12 0.24 Mlig455_053242, Mlig455_066367

Neo: -

Age: -

LHFPL6 0.953 - - 0.953 - - -

Mlig455_053242 {REF} {Length: 1343} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=114.6]; PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=21.4]; Lipid II flippase MurJ [PF03023.16, score=20.7]} {Human: ENSG00000183722, LHFPL6, LHFPL tetraspan subfamily member 6, [RH, Score=81.6, Expect=2e-17]} {Mouse: ENSMUSG00000048332, Lhfp, lipoma HMGIC fusion partner, [RH, Score=79.7, Expect=8e-17]} {Smed: dd_Smed_v6_9373_0_1, dd_Smed_v6_9373_0_1, [RH, Score=181, Expect=4e-53]} {RNA1310_36894} {RNA815_56428}

Mlig455_066367 {REF} {Length: 1706} {Pfam: Lipoma HMGIC fusion partner-like protein [PF10242.11, score=114.6]; PMP-22/EMP/MP20/Claudin tight junction [PF13903.8, score=21.4]; Lipid II flippase MurJ [PF03023.16, score=20.7]} {Human: ENSG00000183722, LHFPL6, LHFPL tetraspan subfamily member 6, [RH, Score=81.6, Expect=2e-17]} {Mouse: ENSMUSG00000048332, Lhfp, lipoma HMGIC fusion partner, [RH, Score=79.7, Expect=8e-17]} {Smed: dd_Smed_v6_9373_0_1, dd_Smed_v6_9373_0_1, [RH, Score=181, Expect=4e-53]} {RNA1509_28410} {RNA1310_83173.1} {RNA815_56428}
70. MligTC455_17269 486 10.13 Mlig455_025715, Mlig455_025767

Neo: -

Age: Up-Down-Down

MAP3K3 0.953 - - - - 0.953 -

Mlig455_025715 {REF} {Length: 8424} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=230.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=149.4]; PB1 domain [PF00564.26, score=24.9]; Fungal protein kinase [PF17667.3, score=22.9]; Kinase-like [PF14531.8, score=20.6]; ABC1 atypical kinase-like domain [PF03109.18, score=18.1]} {Human: ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [RH, Score=344, Expect=6e-105]; ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [RH, Score=341, Expect=1e-103]} {Mouse: ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [RH, Score=338, Expect=6e-103]; ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [RH, Score=336, Expect=5e-102]} {Dmel: FBgn0024329, Mekk1, [Score=163, Expect=3e-40]} {Celegans: WBGene00003822, nsy-1, Mitogen-activated protein kinase kinase kinase nsy-1, [Score=166, Expect=3e-41]} {Smed: dd_Smed_v6_9266_0_1, dd_Smed_v6_9266_0_1, [RH, Score=281, Expect=1e-82]} {RNA1509_28700} {RNA1310_9149} {RNA815_5510}

Mlig455_025767 {REF} {Length: 6531} {TRANSSPLICED} {Pfam: Protein kinase domain [PF00069.27, score=232.7]; Protein tyrosine and serine/threonine kinase [PF07714.19, score=151.4]; PB1 domain [PF00564.26, score=27.0]; Fungal protein kinase [PF17667.3, score=24.7]; Kinase-like [PF14531.8, score=23.5]; ABC1 atypical kinase-like domain [PF03109.18, score=20.0]} {Human: ENSG00000198909, MAP3K3, mitogen-activated protein kinase kinase kinase 3, [RH, Score=348, Expect=1e-112]; ENSG00000169967, MAP3K2, mitogen-activated protein kinase kinase kinase 2, [RH, Score=345, Expect=3e-111]} {Mouse: ENSMUSG00000020700, Map3k3, mitogen-activated protein kinase kinase kinase 3, [RH, Score=344, Expect=4e-111]; ENSMUSG00000024383, Map3k2, mitogen-activated protein kinase kinase kinase 2, [RH, Score=340, Expect=9e-110]} {Dmel: FBgn0024329, Mekk1, [Score=166, Expect=2e-43]} {Celegans: WBGene00001526, gck-1, Germinal center kinase 1, [Score=167, Expect=8e-45]} {Smed: dd_Smed_v6_9266_0_1, dd_Smed_v6_9266_0_1, [RH, Score=286, Expect=1e-89]} {RNA1509_34435, RNA1509_39187} {RNA1310_8418.1, RNA1509_34435, RNA1509_39187} {RNA1509_34435, RNA1509_39187, RNA815_5510}
71. MligTC455_25056 93 1.94 Mlig455_049698, Mlig455_049704

Neo: -

Age: -

Region-enriched R2: 5.783/0.00015

0.953 - - 0.953 - - -

Mlig455_049698 {REF} {Length: 2094} {Smed: dd_Smed_v6_10049_0_1, dd_Smed_v6_10049_0_1, [Score=104, Expect=1e-23]} {RNA1310_40293} {RNA815_29568}

Mlig455_049704 {REF} {Length: 2512} {RNA1509_20101} {RNA1310_40293} {RNA815_29568}
72. MligTC455_51312 38 0.8 Mlig455_015513

Neo: -

Age: -

0.952 - - 0.952 - - - Mlig455_015513 {REF} {Length: 670} {RNA1509_39535} {RNA1310_86982} {RNA815_28901}
73. MligTC455_12897 73 1.52 Mlig455_034188

Neo: -

Age: -

WSCD1 0.951 - - - - 0.951 - Mlig455_034188 {REF} {Length: 929} {Pfam: WSC domain [PF01822.21, score=51.5]; PAN domain [PF00024.28, score=21.2]} {Human: ENSG00000179314, WSCD1, WSC domain containing 1, [Score=65.5, Expect=9e-12]} {Mouse: ENSMUSG00000020811, Wscd1, WSC domain containing 1, [Score=60.1, Expect=4e-10]; ENSMUSG00000040680, Kremen2, kringle containing transmembrane protein 2, [Score=59.7, Expect=5e-10]; ENSMUSG00000020393, Kremen1, kringle containing transmembrane protein 1, [Score=58.2, Expect=2e-09]} {Dmel: FBgn0015360, oxt, peptide O-xylosyltransferase, [Score=52.8, Expect=9e-08]} {RNA1310_39474.1} {RNA815_33128}
74. MligTC455_04675 3 0.07 Mlig455_041371

Neo: -

Age: Up-Down-Down

0.95 - - 0.950 - - - Mlig455_041371 {REF} {Length: 2057} {RNA1509_29127} {RNA1310_6200} {RNA815_31134}
75. MligTC455_07516 112 2.34 Mlig455_060804

Neo: -

Age: -

0.95 - - 0.950 - - - Mlig455_060804 {REF} {Length: 844} {Pfam: Presenilin [PF01080.19, score=19.5]} {RNA1509_21195} {RNA1310_23162} {RNA815_26275}
76. MligTC455_13060 99 2.06 Mlig455_022766

Neo: -

Age: -

0.95 - - 0.950 - - - Mlig455_022766 {REF} {Length: 787} {NoTransDecoderORF} {RNA1310_132565}
77. MligTC455_27648 19 0.39 Mlig455_044670

Neo: -

Age: Up-Up-Down, logFC(26M/2M)=0.920

SZT2 0.95 - - 0.950 - - - Mlig455_044670 {REF} {Length: 12113} {Human: ENSG00000198198, SZT2, SZT2, KICSTOR complex subunit, [Score=82.4, Expect=2e-14]} {Mouse: ENSMUSG00000033253, Szt2, seizure threshold 2, [Score=74.3, Expect=4e-12]} {Smed: dd_Smed_v6_8946_0_1, dd_Smed_v6_8946_0_1, [Score=108, Expect=9e-23]} {RNA1509_25909} {RNA1310_92.1} {RNA815_13061}
78. MligTC455_28142 254 5.3 Mlig455_011323, Mlig455_026058

Neo: -

Age: -

0.95 - - 0.950 - - -

Mlig455_011323 {REF} {Length: 2835} {NoTransDecoderORF} {RNA1509_13222} {RNA1310_24716.1} {RNA815_11419.1}

Mlig455_026058 {REF} {Length: 2664} {TRANSSPLICED} {NoTransDecoderORF} {RNA1509_13222} {RNA1310_24716.1} {RNA815_11419.1}
79. MligTC455_53333 44 0.91 Mlig455_019019, Mlig455_055684

Neo: -

Age: Up-Down-Up

Region-enriched R4: 4.725/0.03950

CHRNA7 0.95 - - 0.950 - - -

Mlig455_019019 {REF} {Length: 2615} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=154.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=93.9]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=210, Expect=2e-59]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=208, Expect=5e-59]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=207, Expect=8e-59]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=206, Expect=3e-58]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=209, Expect=1e-59]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=205, Expect=3e-58]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=221, Expect=3e-63]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=190, Expect=7e-53]} {Smed: dd_Smed_v6_9503_0_1, dd_Smed_v6_9503_0_1, [Score=426, Expect=5e-142]} {RNA1509_56207} {RNA1310_26355} {RNA815_26644}

Mlig455_055684 {REF} {Length: 2604} {Pfam: Neurotransmitter-gated ion-channel ligand binding domain [PF02931.25, score=154.0]; Neurotransmitter-gated ion-channel transmembrane region [PF02932.18, score=94.7]} {Human: ENSG00000175344, CHRNA7, cholinergic receptor nicotinic alpha 7 subunit, [Score=211, Expect=9e-60]; ENSG00000274542, AC243734.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=209, Expect=3e-59]; ENSG00000282088, AC254952.1, cholinergic receptor nicotinic alpha 7 subunit, [Score=208, Expect=5e-59]; ENSG00000120903, CHRNA2, cholinergic receptor nicotinic alpha 2 subunit, [Score=207, Expect=7e-59]} {Mouse: ENSMUSG00000030525, Chrna7, cholinergic receptor, nicotinic, alpha polypeptide 7, [Score=209, Expect=9e-60]; ENSMUSG00000032303, Chrna3, cholinergic receptor, nicotinic, alpha polypeptide 3, [Score=204, Expect=1e-57]} {Dmel: FBgn0000039, nAChRalpha2, nicotinic Acetylcholine Receptor alpha2, [Score=222, Expect=1e-63]} {Celegans: WBGene00006774, unc-38, Acetylcholine receptor subunit alpha-type unc-38, [Score=190, Expect=6e-53]} {Smed: dd_Smed_v6_9503_0_1, dd_Smed_v6_9503_0_1, [Score=427, Expect=3e-142]} {RNA1509_56207} {RNA1310_26355} {RNA815_26644}

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